About

Science

Information

Home

Publications
    Sort by:
Kaufman DS, McDougal WS, Harisinghani MG, Wu CL
Case records of the Massachusetts General Hospital. Case 30-2009. A 77-year-old man with recurrent transitional-cell carcinoma of the ureter.
New Engl J Med. 2009;361(13):1292-9 - PMID: 19776411
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH
HDAC2 negatively regulates memory formation and synaptic plasticity.
Nature. 2009;459(7243):55-60 - PMID: 19424149 - PMCID: PMC3498958
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, Bernstein BE, Kellis M, Regev A, Rinn JL, Lander ES
Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals.
Nature. 2009;458(7235):223-7 - PMID: 19182780 - PMCID: PMC2754849
Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
Nature. 2009;459(7243):103-7 - PMID: 19322176 - PMCID: PMC2761017
Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, C
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276
Andriopoulos Jr B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Nat Genet. 2009;41(4):482-7 - PMID: 19252486 - PMCID: PMC2810136
Chi A, Bernstein B
Developmental biology. Pluripotent chromatin state.
Science. 2009;323(5911):220-1 - PMID: 19131621 - PMCID: PMC4126799
Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A
Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response.
Science. 2009;324(5932):1334-1338 - PMID: 19498172 - PMCID: PMC2803727
Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, Stamatoyannopoulos J, Mirny LA, Lander ES, Dekker J
Comprehensive mapping of long-range interactions reveals folding principles of the human genome.
Science. 2009;326(5950):289-93 - PMID: 19815776 - PMCID: PMC2858594
Swirski* FK, Nahrendorf* M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
Science. 2009;325 (5940):612-6 - PMID: 19644120 - PMCID: PMC2803111
Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A
Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses.
Science. 2009;326(5950):257-63 - PMID: 19729616 - PMCID: PMC2879337
Razansky D, Distel M, Vinegoni C, Ma R, Perrimon N, Koster RW, Ntziachristos V
Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo
Nat Photonics. 2009;3:412 - 417
Khosroshahi A, Stone JR, Pratt DS, Deshpande V, Stone JH
Painless jaundice with serial multi-organ dysfunction.
Lancet Oncol. 2009;373(9673):1494 - PMID: 19394539
Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE
Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA.
Nat Methods. 2009;7(1):47-9 - PMID: 19946276 - PMCID: PMC2862482
Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB
Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis.
Mol Cell. 2009;36(4):682-95 - PMID: 19941827 - PMCID: PMC2800995
Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Handschumacher MD, Sullivan S, Johnson B, Titus JS, Iwamoto Y, Wylie-Sears J, Levine RA, Carpentier A
Active Adaptation of the Tethered Mitral Valve. Insights Into a Compensatory Mechanism for Functional Mitral Regurgitation.
Circulation. 2009;120(4):334-42 - PMID: 19597052 - PMCID: PMC2752046
Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R
Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease.
Circulation. 2009;119(13):1785-94 - PMID: 19307473 - PMCID: PMC2717745
Christen T*, Nahrendorf M*, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P
Molecular Imaging of Innate Immune Cell Function in Transplant Rejection.
Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889
Ronald JA*, Chen JW*, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK
Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques.
Circulation. 2009;120(7):592-9 - PMID: 19652086 - PMCID: PMC2736635
Matter CM, Stuber M, Nahrendorf M
Imaging of the unstable plaque: how far have we got?
Eur Heart J. 2009;30(21):2566-74 - PMID: 19833636 - PMCID: PMC2771148
Jaffer FA
Assessing niacin as an atherosclerosis therapeutic agent valuable insights provided by high-resolution vascular magnetic resonance imaging.
J Am Coll Cardiol. 2009;54(19):1795-6 - PMID: 19874993
Lee H*, Yoon TJ*, Weissleder R
Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System.
Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069
Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R
Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition.
Angew Chem Int Ed Engl. 2009;48(38):7013-6 - PMID: 19697389 - PMCID: PMC2790075
Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis.
Nat Chem Biol. 2009;5(10):734-42 - PMID: 19701185 - PMCID: PMC3032084
Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B, Lin HY, Pietrangelo A, Babitt JL
Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis.
Gastroenterology. 2009;137(4):1489-97 - PMID: 19591830 - PMCID: PMC2757523
Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ
Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.
J Clin Invest. 2009;119(11):3322-8 - PMID: 19809161 - PMCID: PMC2769199
Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA
Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation.
J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134
Shaw SY
Molecular imaging in cardiovascular disease: targets and opportunities.
Nat Rev Cardiol. 2009;6(9):569-79 - PMID: 19621013
Taboada E, Solanas R, Rodriguez E, Weissleder R, Roig A
Supercritical-Fluid-Assisted One-Pot Synthesis of Biocompatible Core (γ-Fe2O3)/Shell(SiO2) Nanoparticles as High Relaxivity T2-Contrast Agents for Magnetic Resonance Imaging
Adv Funct Mater. 2009;19 :2319-2324
Yoo B, Gredler R, Vozhilla N, Su Z, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher P, Sarkar D
Identification of genes conferring resistance to 5-fluorouracil.
Proc Natl Acad Sci U S A. 2009;106(31):12938-43 - PMID: 19622726 - PMCID: PMC2722317
Lee H*, Yoon TJ*, Figueiredo JL, Swirski FK, Weissleder R
Rapid detection and profiling of cancer cells in fine-needle aspirates.
Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371
Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy.
Proc Natl Acad Sci U S A. 2009;106(12):4822-7 - PMID: 19264968 - PMCID: PMC2660771
Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA
Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects.
Proc Natl Acad Sci U S A. 2009;106(35):14932-6 - PMID: 19706423 - PMCID: PMC2736449
Kroh H, Panizzi P, Bock P
Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin.
Proc Natl Acad Sci U S A. 2009;106(19):7786-91 - PMID: 19416890 - PMCID: PMC2683071
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A
Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis.
Proc Natl Acad Sci U S A. 2009;106(8):2712-6 - PMID: 19196966 - PMCID: PMC2650331
Butcher R, Ragains J, Li W, Ruvkun G, Clardy J, Mak H
Biosynthesis of the Caenorhabditis elegans dauer pheromone.
Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283
Hilderbrand SA, Weissleder R
Near-infrared fluorescence: application to in vivo molecular imaging.
Curr Opin Chem Bio. 2009;14:1-9 - PMID: 19879798
Azab A, Runnels J, Pitsillides C, Moreau A, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson A, Alt C, Burwick N, Roccaro A, Ngo H, Farag M, Melhem M, Sacco A, Munshi N, Hideshima T, Rollins B, Anderson K, Kung A, Lin CP, Ghobrial I
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Blood. 2009;113:4341-51 - PMID: 19139079 - PMCID: PMC2676090
Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM
microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma.
Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922
Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM
Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma.
Blood. 2009;114(3):619-29 - PMID: 19443661 - PMCID: PMC2713475
Ueno T, Tanaka K, Jurewicz M, Murayama T, Guleria I, Fiorina P, Paez JC, Augello A, Vergani A, Wong M, Smith RN, Abdi R
Divergent role of donor dendritic cells in rejection versus tolerance of allografts.
J Am Soc Nephrol. 2009;20(3):535-44 - PMID: 19129312 - PMCID: PMC2653678
Corradini E, Babitt JL, Lin HY
The RGM/DRAGON family of BMP co-receptors.
Cytokine Growth Factor Rev. 2009;20(5-6):389-98 - PMID: 19897400 - PMCID: PMC3715994
Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD
Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors.
Cancer Res. 2009;69(8):3472-81 - PMID: 19351838 - PMCID: PMC2785462
McCarthy JR
The future of theranostic nanoagents.
Nanomedicine. 2009;4(7):693-5 - PMID: 19839803
Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS
The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells.
Biomaterials . 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971
Stone JH, Khosroshahi A, Hilgenberg A, Spooner A, Isselbacher EM, Stone JR
IgG4-related systemic disease and lymphoplasmacytic aortitis.
Arthritis Rheum. 2009;60(10):3139-3145 - PMID: 19790067
Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U
Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function.
Arthritis Rheum. 2009;60:2314-2324 - PMID: 19644878 - PMCID: PMC3080016
Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R
MRI of a Novel Murine Working Heart Transplant Model
Circ Heart Fail. 2009;2:272-274 - PMID: 19718275 - PMCID: PMC2733535
Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R
Upconverting luminescent nanomaterials: application to in vivo bioimaging.
Chem Commun. 2009;28:4188-90 - PMID: 19585016 - PMCID: PMC2748243
Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L
A DNA-binding Gd chelate for the detection of cell death by MRI.
Chem Commun. 2009;(29):4444-6 - PMID: 19597620 - PMCID: PMC2754278
Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U
Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation.
Radiology. 2009;251(3):813-21 - PMID: 19474377 - PMCID: PMC2687531
Sosnovik DE
Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques?
Radiology. 2009;251:309-10 - PMID: 19401565
Deguchi JO, Yamazaki H, Aikawa E, Aikawa M
Chronic Hypoxia Activates the Akt and {beta}-Catenin Pathways in Human Macrophages.
Arterioscler Thromb Vasc Biol. 2009;29(10):1664-70 - PMID: 19644051
Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R
Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors.
Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251
Swirski FK, Weissleder R, Pittet MJ
Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(10):1424-32 - PMID: 19372462 - PMCID: PMC2746262 - Cover
Jaffer FA, Libby P, Weissleder R
Optical and Multimodality Molecular Imaging. Insights Into Atherosclerosis.
Arterioscler Thromb Vasc Biol. 2009;29(7):1017-24 - PMID: 19359659 - PMCID: PMC2733228
Hyde D, de Kleine R, MacLaurin S, Miller E, Brooks D, Krucker T, Ntziachristos V
Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model.
Neuroimage. 2009;44(4):1304-11 - PMID: 19041402
McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW
Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy.
Neuroimage. 2009;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831
Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O
Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology
Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476
Zilberman Y, Ballestrem C, Carramusa L, Mazitschek R, Khochbin S, Bershadsky A
Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6.
J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819
Nahrendorf M, Sosnovik D, French B, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ
Multimodality Cardiovascular Molecular Imaging, Part II
Circ Cardiovasc Imaging. 2009;2:56-70 - PMID: 19808565 - PMCID: PMC2760054
Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L
Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia.
Circ Cardiovasc Imaging. 2009;2(6):460-467 - PMID: 19920044 - PMCID: PMC2780438
Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ and Wedeen VJ
Diffusion Spectrum MRI Tractography Reveals the Presence of a Complex Network of Residual Myofibers in Infarcted Myocardium
Circ Cardiovasc Imaging. 2009;2:206-212 - PMID: 19808594 - PMCID: PMC2760045
Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A
Molecular MRI Detects Low Levels of Cardiomyocyte Apoptosis in a Transgenic Model of Chronic Heart Failure.
Circ Cardiovasc Imaging. 2009;2(6):468-475 - PMID: 19920045 - PMCID: PMC2782621
Sosnovik DE, Caravan P
Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents
J Cardiovasc Magn Reson. 2009;2:87-94
Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ
Diffusion MR tractography of the heart.
J Cardiovasc Magn Reson. 2009;11(1):47 - PMID: 19912654 - PMCID: PMC2781805
Im H, Lesuffleur A, Lindquist NC, Oh SH
Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing.
Anal Chem. 2009;81(8):2854-9 - PMID: 19284776 - PMCID: PMC2720634
Koh I, Hong R, Weissleder R, Josephson L
Nanoparticle-Target Interactions Parallel Antibody-Protein Interactions.
Anal Chem. 2009;81(9):3618-22 - PMID: 19323458 - PMCID: PMC2690647
Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J
Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum.
J Med Chem. 2009;52(8):2185-7 - PMID: 19317450 - PMCID: PMC2669731
Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L
The antiproliferative cytostatic effects of a self-activating viridin prodrug.
Mol Cancer Ther. 2009;8(6):1666-1675 - PMID: 19509266 - PMCID: PMC2740925
Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, Garcia-Anoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO
Mutant Sodium Channel for Tumor Therapy.
Mol Cancer Ther. 2009;17(5):810-9 - PMID: 19259066 - PMCID: PMC2751883
Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B
Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1.
Mol Cancer Ther. 2009;18(2):285-94 - PMID: 19844198 - PMCID: PMC2818668
Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton A, Waterman P, Figueiredo JL, Kohler R, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ
Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle
Neoplasia. 2009;11(5):459-468 - PMID: 19412430 - PMCID: PMC2672160 - Cover
Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM
High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model.
ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594
Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ
Implantable diagnostic device for cancer monitoring.
Biosens Bioelectron. 2009;24(11):3252-7 - PMID: 19442510 - PMCID: PMC2738970
Garanger E, Blois J, Hilderbrand SA, Shao F, Josephson L
Divergent Oriented Synthesis For the Design of Reagents for Protein Conjugation.
J Comb Chem. 2009;12(1):57-64 - PMID: 19928910 - PMCID: PMC2877490
Higgins JM, Eddington DT, Bhatia SN, Mahadevan L
Statistical dynamics of flowing red blood cells by morphological image processing.
PLoS Comput Biol. 2009;5(2):e1000288 - PMID: 19214200 - PMCID: PMC2631282
Piccirillo G M, Binda E, Fiocco R, Vescovi L, Shah K
Brain cancer stem cells.
J Mol Med. 2009;87(11):1087-95 - PMID: 19784875
Brown D, Breton S, Ausiello DA, Marshansky V
Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology.
Traffic. 2009;10(3):275-84 - PMID: 19170982 - PMCID: PMC2896909
Tharp A, Laha M, Panizzi P, Thompson M, Fuentes-Prior P, Bock P
Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and Kringle 5 of the substrate.
J Biol Chem. 2009;284(29):19511-21 - PMID: 19473980 - PMCID: PMC2740577
Kawada J, Zou P, Mazitschek R, Bradner JE, Cohen JI
Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis.
J Biol Chem. 2009;284(25):17102-9 - PMID: 19386607 - PMCID: PMC2719348
Chen S, Reynolds F, Yu L, Weissleder R, Josephson L
A screening paradigm for the design of improved polymer-coated superparamagnetic iron oxide nanoparticles
J Mater Chem. 2009;19:6387-6392
Devaraj NK*, Keliher EJ*, Thurber GM, Nahrendorf M, Weissleder R
(18)F Labeled Nanoparticles for in Vivo PET-CT Imaging.
Bioconjug Chem. 2009;20(2):397-401 - PMID: 19138113 - PMCID: PMC2644737
Garanger E, Weissleder R, Josephson L
A Multifunctional Single-Attachment-Point Reagent for Controlled Protein Biotinylation.
Bioconjug Chem. 2009;20(1):170-173 - PMID: 19072220 - PMCID: PMC2692913
Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L
A Wortmannin-Cetuximab as a Double Drug.
Bioconjug Chem. 2009;20 :2185-2189 - PMID: 19883074 - PMCID: PMC3386608
McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA
Multimodal Nanoagents for the Detection of Intravascular Thrombi.
Bioconjug Chem. 2009;20(6):1251-5 - PMID: 19456115 - PMCID: PMC2733224
Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF
A colorimetric high throughput screen for the detection of heme crystallization inhibitors.
Antimicrob Agents Chemother. 2009;53(6):2564-8 - PMID: 19307367 - PMCID: PMC2687197
Bhaumik J, Weissleder R, McCarthy JR
Synthesis and Photophysical Properties of Sulfonamidophenyl Porphyrins as Models for Activatable Photosensitizers.
J Org Chem. 2009;74(16):5894-901 - PMID: 19610602 - PMCID: PMC2888918
Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG
Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.
Int J Radiat Oncol Biol Phys. 2009;74(4):1207-16 - PMID: 19545786 - PMCID: PMC2733223
Macdonald SM, Harisinghani MG, Katkar A, Napolitano B, Wolfgang J, Taghian AG
Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer.
Int J Radiat Oncol Biol Phys. 2009;77(4):1098-104 - PMID: 19836160
Kelly K*, Shaw SY*, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R.
Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries.
Integr Biol (Camb). 2009;1(4):311-317 - PMID: 20023731 - PMCID: PMC2748356 - Cover
Sales VL, Mettler BA, Engelmayr GC, Aikawa E, Bischoff J, Martin DP, Exarhopoulos A, Moses M, Schoen FJ, Sacks M, Mayer J
Endothelial Progenitor Cells as a Sole Source for Ex vivo Seeding of Tissue-engineered Heart Valves.
Tissue Eng. 2009;16(1):257-67 - PMID: 19698056 - PMCID: PMC2811057
Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer J, Aikawa E
Intravital Molecular Imaging of Small-Diameter Tissue-Engineered Vascular Grafts: A Feasibility Study.
Tissue Eng. 2009;16(4):597-607 - PMID: 19751103
Belleannee C, Da Silva N, Shum WW, Marsolais M, Laprade R, Brown D, Breton S
Segmental Expression of the Bradykinin Type 2 Receptor in Rat Efferent Ducts and Epididymis and Its Role in the Regulation of Aquaporin 9.
Biol Reprod. 2009;80(1):134-43 - PMID: 18829705 - PMCID: PMC2804812 - Cover
Pittet MJ
Behavior of immune players in the tumor microenvironment.
Curr Opin Oncol. 2009;21(1):53-9 - PMID: 19125019 - PMCID: PMC2901856
Comper WD, Russo LM
The glomerular filter: an imperfect barrier is required for perfect renal function.
Curr Opin Nephrol Hy. 2009;18(4):336-42 - PMID: 19474730
Deguchi JO, Huang H, Libby P, Aikawa E, Whittaker P, Sylvan J, Lee RT, Aikawa M
Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II.
Lab Invest. 2009;89(3):315-26 - PMID: 19153555 - PMCID: PMC2932654 - Cover
Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U
Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model.
Gynecol Oncol. 2009;112(3):616-22 - PMID: 19135233 - PMCID: PMC2664404
Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U
Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.
Bone. 2009;44:190-198 - PMID: 19007918 - PMCID: PMC2656637
Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S
The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis.
PLoS ONE. 2009;4(2):e4471 - PMID: 19214237 - PMCID: PMC2637605
Wildgruber M, Lee H, Chudnovskiy A, Yoon T, Etzrodt M, Pittet M, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski F
Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors.
PLoS ONE. 2009;4(5):e5663 - PMID: 19461894 - PMCID: PMC2680949
Thurber GM, Figueiredo JL, Weissleder R
Multicolor Fluorescent Intravital Live Microscopy (FILM) for Surgical Tumor Resection in a Mouse Xenograft Model.
PLoS ONE. 2009;4(11):e8053 - PMID: 19956597 - PMCID: PMC2779447
Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S
Systems-level modeling of cancer-fibroblast interaction.
PLoS ONE. 2009;4(9):e6888 - PMID: 19727395 - PMCID: PMC2731225
Bian Y, Sun M, Silver M, Ho KK, Marchionni MA, Caggiano AO, Stone JR, Amende I, Hampton TG, Morgan JP, Yan X
Neuregulin-1 Attenuated Doxorubicin-Induced Decrease in Cardiac Troponins.
Am J Physiol-Heart C. 2009;297(6):H1974-83 - PMID: 19801490 - PMCID: PMC2793128
Bouley R, Palomino Z, Tang SS, Nunes P, Kobori H, Lu HA, Shum WW, Sabolic I, Brown D, Ingelfinger JR, Jung FF
Angiotensin II and Hypertonicity Modulate Proximal Tubular Aquaporin 1 (AQP1) Expression.
Am J Physiol Renal Physiol. 2009;297(6):F1575-86 - PMID: 19776169 - PMCID: PMC2801332
Van Hoek AN, Bouley R, Lu YX, Silberstein CM, Brown D, Wax MB, Patil RV
Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays.
Am J Physiol Renal Physiol. 2009;296(6):F1396-404 - PMID: 19297454 - PMCID: PMC2692439
McCarthy JR, Bhaumik J, Merbouh N, Weissleder R
High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins.
Org Biomol Chem. 2009;7(17):3430-6 - PMID: 19675897 - PMCID: PMC2749955
Ueno T, Kaneko K, Katano H, Sato Y, Mazitschek R, Tanaka K, Hattori S, Irie S, Sata T, Ogawa-Goto K
Expansion of the trans-Golgi network following activated collagen secretion is supported by a coiled-coil microtubule-bundling protein, p180, on the ER.
Exp Cell Res. 2009;316(3):329-40 - PMID: 19932094
Pastor-Soler NM, Fisher JS, Sharpe R, Hill E, Van Hoek A, Brown D, Breton S
Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones.
Reproduction. 2009;139(3):613-21 - PMID: 19948840 - PMCID: PMC3773695
Vinegoni C, Fexon L, Fumene Feruglio P, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R
High throughput transmission optical projection tomography using low cost graphics processing unit
Opt Express. 2009;17(25):22320-22332 - PMID: 20052155 - PMCID: PMC2805020 - Cover
Tsai CC, Vinegoni C, Weissleder R
Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide.
Opt Express. 2009;17(24):21723-31 - PMID: 19997414 - PMCID: PMC2805120
Mansuripur M, Zakharian AR, Lesuffleur A, Oh SH, Jones RJ, Lindquist NC, Im H, Kobyakov A, Moloney JV
Plasmonic nano-structures for optical data storage.
Opt Express. 2009;17(16):14001-14 - PMID: 19654809
Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U
Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects.
Sens Actuat B-Chem. 2009;138(2):591-597 - PMID: 20161242 - PMCID: PMC2706141
Henry F, Cote D, Randolph M, Rust E, Redmond R, Kochevar I, Lin CP, Winograd J
Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy.
Plast Reconstr Surg. 2009;123:123S-30S - PMID: 19182671
Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R
Normalized Born ratio for fluorescence optical projection tomography.
Opt Lett. 2009;34(3):319-21 - PMID: 19183644 - PMCID: PMC2771918
Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R
Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles
Opt Lett. 2009;34(17):2566-8 - PMID: 19724491 - PMCID: PMC2749971
Kumar A, Chung E, Raymond S, van de Water J, Shah K, Fukumura D, Jain R, Bacskai B, Boas D
Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast.
Opt Lett. 2009;34(13):2066-8 - PMID: 19572001 - PMCID: PMC2872111
Vonken EJ, Korosoglou G, Yu J, Schar M, Weissleder R, Stuber M
On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA).
Magn Reson Med. 2009;62(2):314-24 - PMID: 19526511 - PMCID: PMC2742771
Brown D, Paunescu TG, Breton S, Marshansky V
Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking.
J Exp Biol. 2009;212(Pt 11):1762-72 - PMID: 19448085 - PMCID: PMC2683016 - Cover
Shum WW, Da Silva N, Brown D, Breton S
Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk.
J Exp Biol. 2009;212(Pt 11):1753-61 - PMID: 19448084 - PMCID: PMC2683015 - Cover
Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS
Genetically engineered T cells to target EGFRvIII expressing glioblastoma.
J Neuro-Oncol. 2009;94(3):373-82 - PMID: 19387557 - PMCID: PMC2730985
Celso CL, Wu JW, Lin CP
In vivo imaging of hematopoietic stem cells and their microenvironment.
J Biophotonics. 2009;2(11):619-631 - PMID: 19847800
Hilderbrand SA
Labels and probes for live cell imaging: overview and selection guide.
Methods Mol Biol. 2009;591:17-45 - PMID: 19957122
Sun N, Liu Y, Lee H, Weissleder R, Ham D
CMOS RF Biosensor Utilizing Nuclear Magnetic Resonance
IEEE J Solid-ST Circ. 2009;44:1629-1643
Pandharipande PV, Mora JT, Uppot RN, Goehler A, Braschi M, Halpern EF, Gazelle GS, Harisinghani MG
Lymphotropic nanoparticle-enhanced MRI for independent prediction of lymph node malignancy: a logistic regression model.
AJR Am J Roentgenol. 2009;193(3):W230-7 - PMID: 19696264
Baier ND, Hahn PF, Gervais DA, Samir A, Halpern EF, Mueller PR, Harisinghani MG
Fine-needle aspiration biopsy of thyroid nodules: experience in a cohort of 944 patients.
AJR Am J Roentgenol. 2009;193(4):1175-9 - PMID: 19770344
Deliolanis N, Dunham J, Wurdinger T, Figueiredo J, Bakhos T, Ntziachristos V
In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography.
J Biomed Opt. 2009;14(3):030509 - PMID: 19566290 - PMCID: PMC2881930
Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W
Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations.
Arch Pathol Lab Med. 2009;133(12):1949-53 - PMID: 19961250 - PMCID: PMC3694269
Razansky D, Vinegoni C, Ntziachristos V
Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography.
Phys Med Biol. 2009;54:2769-2777 - PMID: 19369709
Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R
Enhancing navigation in biomedical databases by community voting and database-driven text classification.
BMC Bioinformatics. 2009;10(1):317 - PMID: 19799796 - PMCID: PMC2768718
Boland GW, Guimaraes AS, Mueller PR
The evolving radiology landscape: the importance of effective leadership.
Eur J Radiol. 2009;19(10):2321-5 - PMID: 19471944
Rajendran R*, Ronald JA*, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F
Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections.
Microsc Micoranal. 2009;15:338-44 - PMID: 19575834 - PMCID: PMC2802450
Martyn DC, Cortese JF, Tyndall E, Dick J, Mazitschek R, Munoz B, Clardy J
Antiplasmodial activity of piperazine sulfonamides.
Bioorg Med Chem Lett. 2009;20(1):218-21 - PMID: 19914069
Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L
A stabilized demethoxyviridin derivative inhibits PI3 kinase.
Bioorg Med Chem Lett. 2009;19(15):4223-7 - PMID: 19523825 - PMCID: PMC2877487
Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J
Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.
Bioorg Med Chem Lett. 2009;20(1):228-31 - PMID: 19914064
Ueno T, Ikeda T, Ikeda K, Taniuchi H, Suda S, Yeung MY, Matsuno N
HMGB-1 as a Useful Prognostic Biomarker in Sepsis-Induced Organ Failure in Patients Undergoing PMX-DHP.
J Surg Res. 2009;171(1):183-90 - PMID: 20338589
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845
Horner B, Ferguson K, Randolph M, Spencer J, Carlson A, Hirsh E, Lin CP, Butler P
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845
Gee MS, Harisinghani MG, Tabatabaei S
Molecular imaging in urologic surgery.
Urol Clin N Am. 2009;36(2):125-32 - PMID: 19406314
Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R
Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging
J Vis Exp. 2009;28:1389 - PMID: 19578329 - PMCID: PMC2794886
Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R
Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila.
J Vis Exp. 2009;(30):pii:1510 - PMID: 19696720 - PMCID: PMC2736679
Islam T, Harisinghani MG
Overview of nanoparticle use in cancer imaging.
Cancer Biomark. 2009;5:61-7 - PMID: 19414922
Islam T, Wolf G
The pharmacokinetics of the lymphotropic nanoparticle MRI contrast agent ferumoxtran-10.
Cancer Biomark. 2009;5(2):69-73 - PMID: 19414923
Islam T, Josephson L
Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles.
Cancer Biomark. 2009;5(2):99-107 - PMID: 19414927
Harisinghani MG
Nanoparticle enhanced imaging.
Cancer Biomark. 2009;5(2):59 - PMID: 19414921 - Cover
Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M
Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy.
Clin Imaging. 2009;33(4):301-5 - PMID: 19559353
Sosnovik DE
Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach.
Curr Cardiovasc Imaging Rep. 2009;2(1):33-39 - PMID: 20090858 - PMCID: PMC2808047
Sosnovik DE, Caravan P
Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents.
Curr Cardiovasc Imaging Rep. 2009;2(2):87-94 - PMID: 20019886 - PMCID: PMC2794433
Sosnovik DE
Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach
Curr Cardiovasc Imaging Rep. 2009;2:33-39
Miller M, Feng X, Li G, Rabitz H
Nonlinear bionetwork structure inference using the random sampling-high dimensional model representation (RS-HDMR) algorithm.
Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6412-5 - PMID: 19964421
Shah K
Imaging neural stem cell fate in mouse model of glioma.
Curr Protoc Stem Cell Biol. 2009;Chapter 5:Unit5A.1 - PMID: 19306259
Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, Weissleder R
18F-4V for PET-CT Imaging of VCAM-1 Expression in Atherosclerosis
J Am Coll Cardiol Img. 2009;2:1213-1222 - PMID: 19833312 - PMCID: PMC2773129 - Cover
Razansky D, Vinegoni C, Ntziachristos V
Unprecedented in vivo views at the mesoscopic scale
Biooptics World. 2009;2 (4):22-25
Osborn EA, Jaffer FA
The year in molecular imaging.
J Am Coll Cardiol Img. 2009;2:97-113 - PMID: 19356541 - PMCID: PMC4802868
Lesuffleur A, Lim KS, Lindquist NC, Im H, Warrington AE, Rodriguez M, Oh SH
Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment.
Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1481-4 - PMID: 19963504
156 CSV