Silencing of CCR2 in myocarditis.
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Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction
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Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo.
Eur Heart J. 2015;38(6):447-455 - PMID: 26685129 - PMCID: PMC5837565 - DOI: 10.1093/eurheartj/ehv677
Neutrophil-macrophage cross-talk in acute myocardial infarction.
Eur Heart J. 2016;:ePub - PMID: 26984866
Increased haematopoietic activity in patients with atherosclerosis.
Eur Heart J. 2017;38(6):425-432 - PMID: 27357356 - DOI: 10.1093/eurheartj/ehw246
Neutrophil-macrophage cross-talk in acute myocardial infarction.
Eur Heart J. 2017;38(3):198-200 - PMID: 28158564 - PMCID: PMC5837392 - DOI: 10.1093/eurheartj/ehw085
Cholesterol, CCR2, and monocyte phenotypes in atherosclerosis.
Eur Heart J. 2017;38(20):1594-1596 - PMID: 28329093 - DOI: 10.1093/eurheartj/ehx098
Neutrophil contributions to ischaemic heart disease.
Eur Heart J. 2017;38(7):465-472 - PMID: 28363210 - DOI: 10.1093/eurheartj/ehx017
Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases.
Eur Heart J. 2018;39(38):3521-3527 - PMID: 29069365 - PMCID: PMC6174026 - DOI: 10.1093/eurheartj/ehx581
Is defective cholesterol efflux an integral inflammatory component in myelopoiesis-driven cardiovascular diseases?
Eur Heart J. 2018;39(23):2168-2171 - PMID: 29771312 - DOI: 10.1093/eurheartj/ehy269
Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis.
Eur Heart J. 2019;40(30):2482-2491 - PMID: 30698710 - PMCID: PMC6685323 - DOI: 10.1093/eurheartj/ehz008
Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction.
Eur Heart J. 2020;41(9):989-994 - PMID: 30945736 - PMCID: PMC7778432 - DOI: 10.1093/eurheartj/ehz159
Clonal and diverse: revisiting cardiac endothelial cells after myocardial infarction.
Eur Heart J. 2019;40(30):2521-2522 - PMID: 31162523 - PMCID: PMC6685322 - DOI: 10.1093/eurheartj/ehz375
ESC William Harvey Lecture on Basic Science 2020.
Eur Heart J. 2020;41(46):4373-4374 - PMID: 33349865 - DOI: 10.1093/eurheartj/ehaa766
Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis.
Eur Heart J. 2021;42(39):4077-4088 - PMID: 34279021 - PMCID: PMC8516477 - DOI: 10.1093/eurheartj/ehab371
Impact of cholesterol on proinflammatory monocyte production by the bone marrow.
Eur Heart J. 2021;42(42):4309-4320 - PMID: 34343254 - PMCID: PMC8572558 - DOI: 10.1093/eurheartj/ehab465
Immune cells in cardiac homeostasis and disease: emerging insights from novel technologies.
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Mischief in the marrow: a root of cardiovascular evil.
Eur Heart J. 2022;43(19):1829-1831 - PMID: 35567561 - DOI: 10.1093/eurheartj/ehac149
Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci.
Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration
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Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains.
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Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models.
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Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis.
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Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury.
Nat Neurosci. 2023;26(7):1229-1244 - PMID: 37291337 - DOI: 10.1038/s41593-023-01350-3
Shedding light onto live molecular targets
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Fluorescence molecular tomography resolves protease activity in vivo
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In vivo molecular target assessment of matrix metalloproteinase inhibition
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In vivo magnetic resonance imaging of transgene expression
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A spatially and temporally restricted mouse model of soft tissue sarcoma.
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Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone.
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Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo.
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Acidification of the male reproductive tract by a proton pumping (H+)-ATPase.
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In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation
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Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy
Local proliferation dominates lesional macrophage accumulation in atherosclerosis
Therapeutically reeducating macrophages to treat GBM.
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Differential regulation of myeloid leukemias by the bone marrow microenvironment.
Chronic variable stress activates hematopoietic stem cells
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver
IRF3 and type I interferons fuel a fatal response to myocardial infarction
Understanding the tumor immune microenvironment (TIME) for effective therapy.
Nature Med. 2018;24(5):541-550 - PMID: 29686425 - PMCID: PMC5998822 - DOI: 10.1038/s41591-018-0014-x
Myeloid cell contributions to cardiovascular health and disease
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The human heart contains distinct macrophage subsets with divergent origins and functions.
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Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells
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