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Mazitschek R, Mülbaier M, Giannis A
IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids.
Angew Chem Int Ed Engl. 2002;41(21):4059-61 - PMID: 12412081 - DOI: 10.1002/1521-3773(20021104)41:21<4059::AID-ANIE4059>3.0.CO;2-R
Baumhof P, Mazitschek R, Giannis A
A Mild and Effective Method for the Transesterification of Carboxylic Acid Esters P.B. and R.M. are grateful to the Land Baden-Württemberg for a scholarship from the Landesgraduiertenförderung.
Angew Chem Int Ed Engl. 2001;40(19):3672-3674 - PMID: 11592218 - DOI: 10.1002/1521-3773(20011001)40:19<3672::aid-anie3672>3.0.co;2-y
Wernert N, Stanjek A, Kiriakidis S, Hügel A, Jha HC, Mazitschek R, Giannis A
Inhibition of Angiogenesis In Vivo by ets-1 Antisense Oligonucleotides-Inhibition of Ets-1 Transcription Factor Expression by the Antibiotic Fumagillin.
Angew Chem Int Ed Engl. 1999;38(21):3228-3231 - PMID: 10556911 - DOI: 10.1002/(sici)1521-3773(19991102)38:21<3228::aid-anie3228>3.0.co;2-8
Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R
Synthesis of [(18) F]BODIPY: Bifunctional Reporter for Hybrid Optical/Positron Emission Tomography Imaging.
Angew Chem Int Ed Engl. 2012;51(19):4603-6 - PMID: 22473535 - PMCID: PMC3343182 - DOI: 10.1002/anie.201107957
Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R
Bioorthogonal Imaging of Aurora Kinase A in Live Cells.
Angew Chem Int Ed Engl. 2012;51(27):6598-603 - PMID: 22644700 - PMCID: PMC3523717 - DOI: 10.1002/anie.201200994
Budin G*, Chung HJ*, Lee H, Weissleder R
A Magnetic Gram Stain for Bacterial Detection.
Angew Chem Int Ed Engl. 2012;51(31):7752-5 - PMID: 22744868 - PMCID: PMC3496380 - DOI: 10.1002/anie.201202982
Carlson JC, Meimetis LG, Hilderbrand SA, Weissleder R
BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes.
Angew Chem Int Ed Engl. 2013;52(27):6917-6920 - PMID: 23712730 - PMCID: PMC3875324 - DOI: 10.1002/anie.201301100
Yang* KS, Budin* G, Tassa C, Kister O, Weissleder R
Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells
Angew Chem Int Ed Engl. 2013;52(40):10593-7 - PMID: 23960025 - PMCID: PMC3856564 - DOI: 10.1002/anie.201304096
Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R
Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging.
Angew Chem Int Ed Engl. 2014;53(29):7531-4 - PMID: 24915832 - PMCID: PMC4122131 - DOI: 10.1002/anie.201403890
Josephson L, Perez JM, Weissleder R
Magnetic Nanosensors for the Detection of Oligonucleotide Sequences.
Angew Chem Int Ed Engl. 2001;40(17):3204-3206 - PMID: 29712059 - DOI: 10.1002/1521-3773(20010903)40:17<3204::AID-ANIE3204>3.0.CO;2-H
Choudhary A, Manna D, Maji B, Gangopadhyay SA, Cox KJ, Zhou Q, Law B, Mazitschek R
A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9.
Angew Chem Int Ed Engl. 2019;58(19):6285-6289 - PMID: 30834641 - PMCID: PMC7067309 - DOI: 10.1002/anie.201900788
Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R
Ultra-fast cycling for multiplexed cellular fluorescence imaging.
Angew Chem Int Ed Engl. 2020;59(17):6839-6846 - PMID: 32004403 - DOI: 10.1002/anie.201915153
Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB
Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis.
Mol Cell. 2009;36(4):682-95 - PMID: 19941827 - PMCID: PMC2800995 - DOI: 10.1016/j.molcel.2009.11.002
Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, Robinson J, Minie B, Chevrier N, Itzhaki Z, Blecher-Gonen R, Bornstein C, Amann-Zalcenstein D, Weiner A, Friedrich D, Meldrim J, Ram O, Cheng C, Gnirke A, Fisher S, Friedman N, Wong B, Bernstein BE, Nusbaum C, Hacohen N, Regev A, Amit I
A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals.
Mol Cell. 2012;47(5):810-22 - PMID: 22940246 - PMCID: PMC3873101 - DOI: 10.1016/j.molcel.2012.07.030
van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE
A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.
Mol Cell. 2015;61(1):170-80 - PMID: 26687680 - PMCID: PMC4707994 - DOI: 10.1016/j.molcel.2015.11.003
Harisinghani MG, Weissleder R
Sensitive, noninvasive detection of lymph node metastases.
PLoS Med. 2004;1(3):e66 - PMID: 15630471 - PMCID: PMC539052 - DOI: 10.1371/journal.pmed.0010066
Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R
Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma.
PLoS Med. 2008;5(4):e85 - PMID: 18416599 - PMCID: PMC2292750 - DOI: 10.1371/journal.pmed.0050085
Condeelis J, Weissleder R
In Vivo Imaging in Cancer.
Cold Spring Harb Perspect Biol. 2010;2(12):a003848 - PMID: 20861158 - PMCID: PMC2982169 - DOI: 10.1101/cshperspect.a003848
Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg F, Weissleder R, Carson W, Chiocca A, Kaur B.
Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy
J Natl Cancer I. 2007;(99) 23:1768-1781 - PMID: 18042934 - DOI: 10.1093/jnci/djm229
Rashidian M, Keliher E, Dougan M, Juras PK, Cavallari M, Wojtkiewicz GR, Jacobsen J, Edens JG, Tas JM, Victora G, Weissleder R, Ploegh H
The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer.
ACS Cent Sci. 2015;1(3):142-147 - PMID: 26955657 - PMCID: PMC4778250 - DOI: 10.1021/acscentsci.5b00121
Kilic T, Cho YK, Jeong N, Shin IS, Carter BS, Balaj L, Weissleder R, Lee H
Multielectrode Spectroscopy Enables Rapid and Sensitive Molecular Profiling of Extracellular Vesicles.
ACS Cent Sci. 2022;8(1):110-117 - PMID: 35111901 - PMCID: PMC8802188 - DOI: 10.1021/acscentsci.1c01193
Ozsolak F, Goren A, Gymrek MA, Guttman M, Regev A, Bernstein BE, Milos PM
Digital transcriptome profiling from attomole-level RNA samples.
Genome Res. 2010;20(4):519-25 - PMID: 20133332 - PMCID: PMC2847755 - DOI: 10.1101/gr.102129.109
Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, Desalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M
ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia.
Genome Res. 2012;22(9):1813-31 - PMID: 22955991 - PMCID: PMC3431496 - DOI: 10.1101/gr.136184.111
Attanasio C, Nord AS, Zhu Y, Blow MJ, Biddie SC, Mendenhall EM, Dixon J, Wright CA, Hosseini R, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Afzal V, Ren B, Bernstein B, Rubin E, Visel A, Pennacchio L
Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.
Genome Res. 2014;24(6):920-9 - PMID: 24752179 - PMCID: PMC4032856 - DOI: 10.1101/gr.168930.113
Perez JM, Simeone FJ, Saeki Y, Josephson L, Weissleder R
Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media
J Am Chem Soc. 2003;125:10192-3 - PMID: 12926940 - DOI: 10.1021/ja036409g
Perez JM, O'Loughin T, Simeone F J, Weissleder R, Josephson L
DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents
J Am Chem Soc. 2002;124:2856-7 - PMID: 11902860 - DOI: 10.1021/ja017773n
E.C. Wiener, F.P. Auteri, J.W. Chen, M.W. Brechbiel, O.A. Gansow, D.J. Schneider, R.L. Belford, R.B. Clarkson, P.C. Lauterbur
Molecular Dynamics of Ion-Chelate Complexes Attached to Starburst(TM) Dendrimers
J Am Chem Soc. 1996;118:7774-7782
Hilderbrand S, Lim M, Lippard S
Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors.
J Am Chem Soc. 2004;126:4972-8 - PMID: 15080703 - DOI: 10.1021/ja038471j
Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA
Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation.
J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134 - DOI: 10.1021/ja903922u
Rodriguez E, Nilges M, Weissleder R, Chen JW
Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity.
J Am Chem Soc. 2010;132(1):168-77 - PMID: 19968300 - PMCID: PMC2802665 - DOI: 10.1021/ja905274f
Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG
Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots Using Tetrazine-Norbornene Cycloaddition.
J Am Chem Soc. 2010;132(23):7838-9 - PMID: 20481508 - PMCID: PMC2892974 - DOI: 10.1021/ja101677r
Brueckner C, Gotz DC, Fox SP, Ryppa C, McCarthy JR, Bruhn T, Akhigbe J, Banerjee S, Daddario P, Daniell HW, Zeller M, Boyle R, Bringmann G
Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins.
J Am Chem Soc. 2011;133(22):8740-8752 - PMID: 21534626 - DOI: 10.1021/ja202451t
Stahl P, Kissau L, Mazitschek R, Huwe A, Furet P, Giannis A, Waldmann H
Total synthesis and biological evaluation of the nakijiquinones.
J Am Chem Soc. 2001;123(47):11586-93 - PMID: 11716712 - DOI: 10.1021/ja011413i
Niers JM*, Chen JW*, Lewandrowski G, Kerami M, Garanger E, Wojtkiewicz G, Waterman P, Keliher E, Weissleder R, Tannous BA
Single Reporter for Targeted Multimodal in Vivo Imaging.
J Am Chem Soc. 2012;134(11):5149-56 - PMID: 22397453 - PMCID: PMC3310895 - DOI: 10.1021/ja209868g
Agasti SS, Liong M, Peterson VM, Lee H, Weissleder R
Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cell.
J Am Chem Soc. 2012;134(45):18499-18502 - PMID: 23092113 - PMCID: PMC3498844 - DOI: 10.1021/ja307689w
Chen YC, Backus KM, Merkulova M, Yang C, Brown D, Cravatt BF, Zhang C
Covalent Modulators of the Vacuolar ATPase.
J Am Chem Soc. 2016;139(2):639-642 - PMID: 28010062 - PMCID: PMC5274637 - DOI: 10.1021/jacs.6b12511
Chen CH, Sarkar A, Song YA, Miller MA, Kim SJ, Griffith LG, Lauffenburger DA, Han J
Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator.
J Am Chem Soc. 2011;133(27):10368-71 - PMID: 21671557 - PMCID: PMC3165005 - DOI: 10.1021/ja2036628
Chen CH, Miller MA, Sarkar A, Beste MT, Isaacson KB, Lauffenburger DA, Griffith LG, Han J
Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis.
J Am Chem Soc. 2012;135(5):1645-8 - PMID: 23157326 - PMCID: PMC3566300 - DOI: 10.1021/ja307866z
Carlson J, Mikula H, Weissleder R
Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage.
J Am Chem Soc. 2018;140(10):3603-3612 - PMID: 29384666 - PMCID: PMC5857921 - DOI: 10.1021/jacs.7b11217
Wilkovitsch M, Haider M, Sohr B, Herrmann B, Klubnick J, Weissleder R, Carlson JCT*, Mikula H*
A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes.
J Am Chem Soc. 2020;142(45):19132-19141 - PMID: 33119297 - PMCID: PMC7662912 - DOI: 10.1021/jacs.0c07922
Syeda R, Holden MA, Hwang WL, Bayley H
Screening blockers against a potassium channel with a droplet interface bilayer array.
J Am Chem Soc. 2008;130(46):15543-8 - PMID: 18950170 - DOI: 10.1021/ja804968g
Hwang WL, Chen M, Cronin B, Holden MA, Bayley H
Asymmetric droplet interface bilayers.
J Am Chem Soc. 2008;130(18):5878-9 - PMID: 18407631 - DOI: 10.1021/ja802089s
Hwang WL, Holden MA, White S, Bayley H
Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling.
J Am Chem Soc. 2007;129(38):11854-64 - PMID: 17764183 - DOI: 10.1021/ja074071a
Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC
Identification of the target self-antigens in reperfusion injury.
J Exp Med. 2006;203(1):141-152 - PMID: 16390934 - PMCID: PMC2118091 - DOI: 10.1084/jem.20050390
Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D.
Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk
J Exp Med. 2007;204:1911-1922 - PMID: 17646407 - PMCID: PMC2118664 - DOI: 10.1084/jem.20070285
Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions.
J Exp Med. 2007;204(12):3037-47 - PMID: 18025128 - PMCID: PMC2118517 - DOI: 10.1084/jem.20070885
Zippelius A, Pittet M, Batard P, Rufer N, de Smedt M, Guillaume P, Ellefsen K, Valmori D, Lienard D, Plum J, MacDonald H, Speiser D, Cerottini J, Romero P
Thymic selection generates a large T cell pool recognizing a self-peptide in humans.
J Exp Med. 2002;195:485-94 - PMID: 11854361 - PMCID: PMC2193620 - DOI: 10.1084/jem.20011658
Dutoit V, Rubio-Godoy V, Pittet M, Zippelius A, Dietrich P, Legal F, Guillaume P, Romero P, Cerottini J, Houghten R, Pinilla C, Valmori D
Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans.
J Exp Med. 2002;196:207-16 - PMID: 12119345 - PMCID: PMC2193921 - DOI: 10.1084/jem.20020242
Romero P, Dunbar P, Valmori D, Pittet M, Ogg G, Rimoldi D, Chen J, Lienard D, Cerottini J, Cerundolo V
Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes.
J Exp Med. 1998;188:1641-50 - PMID: 9802976 - PMCID: PMC2212507 - DOI: 10.1084/jem.188.9.1641
Speiser D, Pittet M, Valmori D, Dunbar R, Rimoldi D, Lienard D, MacDonald H, Cerottini J, Cerundolo V, Romero P
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes.
J Exp Med. 1999;190:775-82 - PMID: 10499916 - PMCID: PMC2195637 - DOI: 10.1084/jem.190.6.775
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