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Senders ML, Calcagno C, Tawakol A, Nahrendorf M, Mulder WJM, Fayad ZA PET/MR imaging of inflammation in atherosclerosis. Nat Biomed Eng. 2022;7(3):202-220 - PMID: 36522465 - DOI: 10.1038/s41551-022-00970-7
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Foy BH, Sundt TM, Carlson JCT, Aguirre AD, Higgins JM Human acute inflammatory recovery is defined by co-regulatory dynamics of white blood cell and platelet populations. Nat Commun. 2022;13(1):4705 - PMID: 35995789 - PMCID: PMC9395541 - DOI: 10.1038/s41467-022-32222-2
Tye MA, Payne NC, Johansson C, Singh K, Santos SA, Fagbami L, Pant A, Sylvester K, Luth MR, Marques S, Whitman M, Mota MM, Winzeler EA, Lukens AK, Derbyshire ER, Oppermann U, Wirth DF, Mazitschek R Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance. Nat Commun. 2022;13(1):4976 - PMID: 36008486 - PMCID: PMC9403976 - DOI: 10.1038/s41467-022-32630-4
Momin N, Palmeri JR, Lutz EA, Jailkhani N, Mak H, Tabet A, Chinn MM, Kang BH, Spanoudaki V, Hynes RO, Wittrup KD Maximizing response to intratumoral immunotherapy in mice by tuning local retention. Nat Commun. 2022;13(1):109 - PMID: 35013154 - PMCID: PMC8748612 - DOI: 10.1038/s41467-021-27390-6
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Tian T, Liang R, Erel-Akbaba G, Saad L, Obeid PJ, Gao J, Chiocca EA, Weissleder R, Tannous BA Immune Checkpoint Inhibition in GBM Primed with Radiation by Engineered Extracellular Vesicles. ACS Nano. 2022;16(2):1940-1953 - PMID: 35099172 - PMCID: PMC9020451 - DOI: 10.1021/acsnano.1c05505
Patel NJ, Tozzo V, Higgins JM, Stone JH The effects of daily prednisone and tocilizumab on hemoglobin A1c during the treatment of giant cell arteritis. Arthritis Rheumatol. 2022;75(4):586-594 - PMID: 36383175 - DOI: 10.1002/art.42405
Peterson HM, Chin LK, Iwamoto Y, Oh J, Carlson JCT, Lee H, Im H, Weissleder R Integrated Analytical System for Clinical Single-Cell Analysis Adv Sci (Weinh). 2022;9(20):e2200415 - PMID: 35508767 - PMCID: PMC9284190 - DOI: 10.1002/advs.202200415
Kim H, Sa JK, Kim J, Cho HJ, Oh HJ, Choi DH, Kang SH, Jeong DE, Nam DH, Lee H, Lee HW, Chung S Recapitulated Crosstalk between Cerebral Metastatic Lung Cancer Cells and Brain Perivascular Tumor Microenvironment in a Microfluidic Co-Culture Chip. Adv Sci (Weinh). 2022;9(22):e2201785 - PMID: 35657027 - PMCID: PMC9353479 - DOI: 10.1002/advs.202201785
Ko J, Lucas K, Kohler RH, Halabi EA, Wilkovitsch M, Carlson JCT, Weissleder R In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy Adv Sci (Weinh). 2022;9(24):e2200064 - PMID: 35750648 - PMCID: PMC9405492 - DOI: 10.1002/advs.202200064
Kilic T, Cho YK, Jeong N, Shin IS, Carter BS, Balaj L, Weissleder R, Lee H Multielectrode Spectroscopy Enables Rapid and Sensitive Molecular Profiling of Extracellular Vesicles. ACS Cent Sci. 2022;8(1):110-117 - PMID: 35111901 - PMCID: PMC8802188 - DOI: 10.1021/acscentsci.1c01193
McAlpine CS, Kiss MG, Zuraikat FM, Cheek D, Schiroli G, Amatullah H, Huynh P, Bhatti MZ, Wong LP, Yates AG, Poller WC, Mindur JE, Chan CT, Janssen H, Downey J, Singh S, Sadreyev RI, Nahrendorf M, Jeffrey KL, Scadden DT, Naxerova K, St-Onge MP, Swirski FK Sleep exerts lasting effects on hematopoietic stem cell function and diversity. J Exp Med. 2022;219(11):ePub - PMID: 36129517 - PMCID: PMC9499822 - DOI: 10.1084/jem.20220081
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Ferguson S, Yang KS, Zelga P, Liss AS, Carlson JCT, Del Castillo CF, Weissleder R Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer. Sci Adv. 2022;8(16):eabm3453 - PMID: 35452280 - PMCID: PMC9032977 - DOI: 10.1126/sciadv.abm3453
Ng TSC, Hu H, Kronister S, Lee C, Li R, Gerosa L, Stopka SA, Burgenske DM, Khurana I, Regan MS, Vallabhaneni S, Putta N, Scott E, Matvey D, Giobbie-Hurder A, Kohler RH, Sarkaria JN, Parangi S, Sorger PK, Agar NYR, Jacene HA, Sullivan RJ, Buchbinder E, Mikula H, Weissleder R, Miller MA Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy. Sci Adv. 2022;8(17):eabl6339 - PMID: 35486732 - PMCID: PMC9054019 - DOI: 10.1126/sciadv.abl6339
Cho YK, Kim H, Bénard A, Woo HK, Czubayko F, David P, Hansen FJ, Lee JI, Park JH, Schneck E, Weber GF, Shin IK, Lee H Electrochemiluminescence in paired signal electrode (ECLipse) enables modular and scalable biosensing Sci Adv. 2022;8:eabq4022 - PMID: 36129990 - PMCID: PMC9491722 - DOI: 10.1126/sciadv.abq4022
Hu H, Quintana J, Weissleder R, Parangi S, Miller M Deciphering albumin-directed drug delivery by imaging. Adv Drug Deliv Rev. 2022;185:114237 - PMID: 35364124 - PMCID: PMC9117484 - DOI: 10.1016/j.addr.2022.114237
Ozturk H, Cingoz H, Tufan T, Yang J, Adair SJ, Tummala KS, Kuscu C, Kinali M, Comertpay G, Nagdas S, Goudreau BJ, Luleyap HU, Bingul Y, Ware TB, Hwang WL, Hsu KL, Kashatus DF, Ting DT, Chandel NS, Bardeesy N, Bauer TW, Adli M ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer. Dev Cell. 2022;57(11):1331-1346.e9 - PMID: 35508175 - DOI: 10.1016/j.devcel.2022.04.014
Lutz EA, Agarwal Y, Momin N, Cowles SC, Palmeri JR, Duong E, Hornet V, Sheen A, Lax BM, Rothschilds AM, Irvine DJ, Spranger S, Wittrup KD Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies. Proc Natl Acad Sci U S A. 2022;119(36):e2205983119 - PMID: 36037341 - PMCID: PMC9457244 - DOI: 10.1073/pnas.2205983119
Oh HK, Kim K, Park J, Im H, Maher S, Kim MG Plasmon color-preserved gold nanoparticle clusters for high sensitivity detection of SARS-CoV-2 based on lateral flow immunoassay. Biosens Bioelectron. 2022;205:114094 - PMID: 35202985 - PMCID: PMC8851749 - DOI: 10.1016/j.bios.2022.114094
Ferguson S, Yang KS, Weissleder R Single extracellular vesicle analysis for early cancer detection Trends in Molecular Medicine. 2022;28(8):681-692 - PMID: 35624008 - PMCID: PMC9339504 - DOI: 10.1016/j.molmed.2022.05.003
Woo HK, Cho YK, Lee CY, Lee H, Castro CM, Lee H Characterization and modulation of surface charges to enhance extracellular vesicle isolation in plasma. Theranostics. 2022;12(5):1988-1998 - PMID: 35265194 - PMCID: PMC8899565 - DOI: 10.7150/thno.69094 - Cover
Hsia T, Yekula A, Batool SM, Rosenfeld YB, You DG, Weissleder R, Lee H, Carter BS, Balaj L Glioblastoma-derived extracellular vesicle subpopulations following 5-aminolevulinic acid treatment bear diagnostic implications. J Extracell Vesicles. 2022;11(11):e12278 - PMID: 36404434 - PMCID: PMC9676504 - DOI: 10.1002/jev2.12278
Liu T, Meng Z, Liu J, Li J, Zhang Y, Deng Z, Luo S, Wang M, Huang Q, Zhang S, Fendt P, Devouassoux J, Li D, McKenzie ANJ, Nahrendorf M, Libby P, Guo J, Shi GP Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells. Cardiovasc Res. 2022;119(4):1046-1061 - PMID: 36063432 - PMCID: PMC10153644 - DOI: 10.1093/cvr/cvac144
Bapat A, Li G, Xiao L, Yeri A, Hulsmans M, Grune J, Yamazoe M, Schloss MJ, Iwamoto Y, Tedeschi JG, Yang X, Nahrendorf M, Rosenzweig A, Ellinor PT, Das S, Milan D Genetic inhibition of serum glucocorticoid kinase 1 prevents obesity-related atrial fibrillation. JCI Insight. 2022;7(19):ePub - PMID: 35998035 - PMCID: PMC9675459 - DOI: 10.1172/jci.insight.160885
Kim K, Son T, Hong JS, Kwak TJ, Jeong MH, Weissleder R, Im H Physisorption of Affinity Ligands Facilitates Extracellular Vesicle Detection with Low Non-Specific Binding to Plasmonic Gold Substrates. ACS Appl Mater Interfaces. 2022;:ePub - PMID: 35653580 - PMCID: PMC9715849 - DOI: 10.1021/acsami.2c07317
Chin LK, Li H, Choi JH, Iwamoto Y, Oh J, Min J, Beak SK, Yoo D, Castro CM, Lee D, Im H Hydrogel Stamping for Rapid, Multiplexed, Point-of-Care Immunostaining of Cells and Tissues. ACS Appl Mater Interfaces. 2022;14(24):27613-27622 - PMID: 35671240 - DOI: 10.1021/acsami.2c05071
Ng TSC, Allen HH, Rashidian M, Miller MA Probing immune infiltration dynamics in cancer by in-vivo imaging. Curr Opin Chem Biol. 2022;67:102117 - PMID: 35219177 - PMCID: PMC9118268 - DOI: 10.1016/j.cbpa.2022.102117
Payne NC, Mazitschek R Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors. Cell Chem Biol. 2022;29(7):1140-1152.e5 - PMID: 35298895 - DOI: 10.1016/j.chembiol.2022.03.002
Payne NC, Maksoud S, Tannous BA, Mazitschek R A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader. Cell Chem Biol. 2022;29(8):1333-1340.e5 - PMID: 35649410 - PMCID: PMC9391279 - DOI: 10.1016/j.chembiol.2022.05.003
Giacomini KM, Yee SW, Koleske ML, Zou L, Matsson P, Chen E, Kroetz DL, Miller MA, Gozalpour E, Chu X New and emerging research on solute carrier (SLC) and ABC transporters in drug discovery and development: Outlook from the International Transporter Consortium. Clin Pharmacol Ther. 2022;112(3):540-561 - PMID: 35488474 - PMCID: PMC9398938 - DOI: 10.1002/cpt.2627
Szafraniec HM, Valdez JM, Iffrig E, Lam WA, Higgins JM, Pearce P, Wood DK Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood. Lab Chip. 2022;22(8):1565-1575 - PMID: 35315465 - PMCID: PMC9004467 - DOI: 10.1039/d1lc01133b
Lucas K, Oh J, Hoelzl J, Weissleder R Cellular point-of-care diagnostics using an inexpensive layer-stack microfluidic device. Lab Chip. 2022;22:2145 - 2154 - PMID: 35514273 - PMCID: PMC9214713 - DOI: 10.1039/d2lc00162d
Iyer V, Yang Z, Ko J, Weissleder R, Issadore D Advancing microfluidic diagnostic chips into clinical use: a review of current challenges and opportunities. Lab Chip. 2022;22(17):3110-3121 - PMID: 35674283 - PMCID: PMC9798730 - DOI: 10.1039/d2lc00024e
Seldon CS, Meiyappan K, Hoffman H, Guo JA, Goel N, Hwang WL, Nguyen PL, Mahal BA, Alshalalfa M Genomic alterations predictive of poor clinical outcomes in pan-cancer. Oncotarget. 2022;13:1069-1077 - PMID: 36187555 - PMCID: PMC9518688 - DOI: 10.18632/oncotarget.28276
Shiau C, Su J, Guo JA, Hong TS, Wo JY, Jagadeesh KA, Hwang WL Treatment-associated remodeling of the pancreatic cancer endothelium at single-cell resolution. Front Oncol. 2022;12:929950 - PMID: 36185212 - PMCID: PMC9524152 - DOI: 10.3389/fonc.2022.929950
Cook L, Sengelmann M, Winkler B, Nagl C, Koch S, Schlomann U, Slater EP, Miller MA, von Strandmann EP, Dorsam B, Preuber C, Bartsch JW ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9. Int J Mol Sci. 2022;23(4):ePub - PMID: 35216088 - PMCID: PMC8875419 - DOI: 10.3390/ijms23041976
Truslow JG, Goto S, Homilius M, Mow C, Higgins JM, MacRae CA, Deo RC Cardiovascular Risk Assessment Using Artificial Intelligence-Enabled Event Adjudication and Hematologic Predictors. Circ Cardiovasc Qual Outcomes. 2022;15(6):e008007 - PMID: 35477255 - PMCID: PMC9208816 - DOI: 10.1161/CIRCOUTCOMES.121.008007
Ali M, Fulci G, Grigalavicius M, Pulli B, Li A, Wojtkiewicz GR, Wang C, Hsieh KL, Linnoila JJ, Theodossiou TA, Chen JW Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy. Neoplasia. 2022;26:100779 - PMID: 35247801 - PMCID: PMC8894277 - DOI: 10.1016/j.neo.2022.100779
Li JH, Forghani R, Bure L, Wojtkiewicz GR, Wu Y, Iwamoto Y, Ali M, Li A, Wang C, Jalali Motlagh N, Papadakis AI, Pusztaszeri MP, Spatz A, Curtin H, Cheng YS, Chen JW Molecular immuno-imaging improves tumor detection in head and neck cancer. FASEB J. 2022;36(1):e22092 - PMID: 34919761 - PMCID: PMC9584652 - DOI: 10.1096/fj.202100864R
Keung EZ, Krause KJ, Maxwell J, Morris CD, Crago AM, Houdek MT, Kane J, Lewis V, Callegaro D, Miller B, Lazar AJ, Gladdy R, Raut CP, Fabbri N, Al-Refaie W, Fairweather M, Wong SL, Roland CL Sentinel Lymph Node Biopsy for Extremity and Truncal Soft Tissue Sarcomas: A Systematic Review of the Literature. Ann Surg Oncol. 2022;30(2):958-967 - PMID: 36307665 - DOI: 10.1245/s10434-022-12688-6
Park BJ, Mattox AK, Clayburgh D, Patel M, Bell RB, Yueh B, Leidner R, Xiao H, Couey M, Li S, Qin T, Sartor MA, Cairns B, MacDonough T, Halliwill K, Deschler D, Lin DT, Faquin WC, Sadow PM, Pai SI Chemoradiation therapy alters the PD-L1 score in locoregional recurrent squamous cell carcinomas of the head and neck. Oral Oncol. 2022;135:106183 - PMID: 36215771 - PMCID: PMC10283355 - DOI: 10.1016/j.oraloncology.2022.106183
Leming M, Das S, Im H Construction of a confounder-free clinical MRI dataset in the Mass General Brigham system for classification of Alzheimer's disease. Artif Intell Med. 2022;129:102309 - PMID: 35659387 - PMCID: PMC9295028 - DOI: 10.1016/j.artmed.2022.102309
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Park JH, Park EK, Cho YK, Shin IS, Lee H Normalizing the Optical Signal Enables Robust Assays with Lateral Flow Biosensors. ACS Omega. 2022;7(21):17723-17731 - PMID: 35664567 - PMCID: PMC9161384 - DOI: 10.1021/acsomega.2c00793
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Aguirre AD, Shelton KT Remote monitoring in the use of extracorporeal membrane oxygenation and acute mechanical circulatory support. Curr Opin Crit Care. 2022;28(3):308-314 - PMID: 35653252 - DOI: 10.1097/MCC.0000000000000949
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Guo JA, Alshalalfa M, Kim DY, Hoffman HI, Shiau C, Su J, Hwang WL, Mahal BA DNA repair and immune checkpoint blockade response. Cancer Genet. 2022;264-265:1-4 - PMID: 35245846 - DOI: 10.1016/j.cancergen.2022.02.007
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Lutz EA, Jailkhani N, Momin N, Huang Y, Sheen A, Kang BH, Wittrup KD, Hynes RO Intratumoral nanobody-IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice. PNAS Nexus. 2022;1(5):pgac244 - PMID: 36712341 - PMCID: PMC9802395 - DOI: 10.1093/pnasnexus/pgac244
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