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Pessoa Rodrigues C, Collins JM, Yang S, Martinez C, Kim JW, Lama C, Nam AS, Alt C, Lin C, Zon LI Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells. Science. 2024;385(6714):eadn1629 - PMID: 39264994 - DOI: 10.1126/science.adn1629

Shiau C, Cao J, Gong D, Gregory MT, Caldwell NJ, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Bae JW, Zhao R, Schurman N, Barth JL, Ganci ML, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Castillo CF, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment. Nat Genet. 2024;:ePub - PMID: 39227743 - DOI: 10.1038/s41588-024-01890-9

Guan D, Men Y, Bartlett A, Hernández MAS, Xu J, Yi X, Li HS, Kong D, Mazitschek R, Ozcan U Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss. Cell Metab. 2024;36(4):857-876.e10 - PMID: 38569472 - DOI: 10.1016/j.cmet.2024.02.007

Grune J, Bajpai G, Ocak PT, Kaufmann E, Mentkowksi K, Pabel S, Kumowski N, Pulous FE, Tran KA, Rohde D, Zhang S, Iwamoto Y, Wojtkiewicz GR, Vinegoni C, Green U, Swirski FK, Stone JR, Lennerz JK, Divangahi M, Hulsmans M, Nahrendorf M Virus-Induced Acute Respiratory Distress Syndrome Causes Cardiomyopathy Through Eliciting Inflammatory Responses in the Heart. Circulation. 2024;150(1):49-61 - PMID: 38506045 - PMCID: PMC11216864 - DOI: 10.1161/CIRCULATIONAHA.123.066433

Carrow KP, Hamilton HL, Hopps MP, Li Y, Qiao B, Payne NC, Thompson MP, Zhang X, Magassa A, Fattah M, Agarwal S, Vincent MP, Buyanova M, Bertin PA, Mazitschek R, Olvera de la Cruz M, Johnson DA, Johnson JA, Gianneschi NC Inhibiting the Keap1/Nrf2 Protein-Protein Interaction with Protein-Like Polymers. Adv Mater. 2024;36(21):e2311467 - PMID: 38241649 - PMCID: PMC11257647 - DOI: 10.1002/adma.202311467

Kang M, Quintana J, Hu H, Teixeira VC, Olberg S, Banla LI, Rodriguez V, Hwang WL, Schuemann J, Parangi S, Weissleder R, Miller MA Sustained and Localized Drug Depot Release using Radiation-Activated Scintillating Nanoparticles. Adv Mater. 2024;36(23):e2312326 - PMID: 38389502 - PMCID: PMC11161319 - DOI: 10.1002/adma.202312326

Chen ACY, Jaiswal S, Martinez D, Yerinde C, Ji K, Miranda V, Fung ME, Weiss SA, Zschummel M, Taguchi K, Garris CS, Mempel TR, Hacohen N, Sen DR The aged tumor microenvironment limits T cell control of cancer. Nat Immunol. 2024;25(6):1033-1045 - PMID: 38745085 - DOI: 10.1038/s41590-024-01828-7

Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, Ferroni L, Zhang Y, Jung Y, Sales G, Martini P, Nakamura T, Lasorsa FM, Finkel T, Lin CP, Zavan B, Pinton P, Georgakoudi I, Romualdi C, Scadden DT, Ito K A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate. Cell Stem Cell. 2024;31(3):359-377.e10 - PMID: 38458178 - PMCID: PMC10957094 - DOI: 10.1016/j.stem.2024.02.004

Barth I, Lee H Phase-driven progress in nanophotonic biosensing. Light Sci Appl. 2024;13(1):76 - PMID: 38494520 - PMCID: PMC10944832 - DOI: 10.1038/s41377-024-01415-3

Stollmann A, Garcia-Guirado J, Hong JS, Rüedi P, Im H, Lee H, Ortega Arroyo J, Quidant R Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform. Nat Commun. 2024;15(1):4109 - PMID: 38750038 - PMCID: PMC11096335 - DOI: 10.1038/s41467-024-48132-4

Diez I, Ortiz-Terán L, Ng TSC, Albers MW, Marshall G, Orwig W, Kim CM, Bueichekú E, Montal V, Olofsson J, Vannini P, El Fahkri G, Sperling R, Johnson K, Jacobs HIL, Sepulcre J Tau propagation in the brain olfactory circuits is associated with smell perception changes in aging. Nat Commun. 2024;15(1):4809 - PMID: 38844444 - PMCID: PMC11156945 - DOI: 10.1038/s41467-024-48462-3

Lee CY, Kim H, Degani I, Lee H, Sandoval A, Nam Y, Pascavis M, Park HG, Randall T, Ly A, Castro CM, Lee H Empowering the on-site detection of nucleic acids by integrating CRISPR and digital signal processing. Nat Commun. 2024;15(1):6271 - PMID: 39054353 - PMCID: PMC11272939 - DOI: 10.1038/s41467-024-50588-3

Halabi EA, Gessner I, Yang K, Kim JJ, Jana R, Peterson HM, Spitzberg J, Weissleder R Magnetic Silica-Coated Fluorescent Microspheres (MagSiGlow) for Simultaneous Detection of Tumor-Associated Proteins. Angew Chem Int Ed Engl. 2024;63(24):e202318870 - PMID: 38578432 - DOI: 10.1002/anie.202318870

Hammel FA, Payne NC, Marando VM, Mazitschek R, Walker S Identification of a Polypeptide Inhibitor of O-GlcNAc Transferase with Picomolar Affinity. J Am Chem Soc. 2024;:ePub - PMID: 39276112 - DOI: 10.1021/jacs.4c08656

Tozzo V, Genco M, Omololu SO, Mow C, Patel HR, Patel CH, Ho SN, Lam E, Abdulsater B, Patel N, Cohen RM, Nathan DM, Powe CE, Wexler DJ, Higgins JM Estimating Glycemia From HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy. Diabetes Care. 2024;47(3):460-466 - PMID: 38394636 - PMCID: PMC10909686 - DOI: 10.2337/dc23-1177

Welsh, JA Goberdhan, DCI O'Driscoll, L Buzas, EI Blenkiron, C Bussolati, B Cai, H Di Vizio, D Driedonks, TAP Erdbrügger, U Falcon-Perez, JM Fu, QL Hill, AF Lenassi, M Lim, SK Mahoney, MG Mohanty, S Möller, A Nieuwland, R Ochiya, T Sahoo, S Torrecilhas, AC Zheng, L Zijlstra, A Abuelreich, S Bagabas, R Bergese, P Bridges, EM Brucale, M Burger, D Carney, RP Cocucci, E Crescitelli, R Hanser, E Harris, AL Haughey, NJ Hendrix, A Ivanov, AR Jovanovic-Talisman, T Kruh-Garcia, NA Ku'ulei-Lyn Faustino, V Kyburz, D Lässer, C Lennon, KM Lötvall, J Maddox, AL Martens-Uzunova, ES Mizenko, RR Newman, LA Ridolfi, A Rohde, E Rojalin, T Rowland, A Saftics, A Sandau, US Saugstad, JA Shekari, F Swift, S Ter-Ovanesyan, D Tosar, JP Useckaite, Z Valle, F Varga, Z van der Pol, E van Herwijnen, MJC Wauben, MHM Wehman, AM Williams, S Zendrini, A Zimmerman, AJ MISEV, Consortium Théry, C Witwer, KW Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches J Extracell Vesicles. 2024;2:e12404 - PMID: 38326288 - PMCID: PMC10850029 - DOI: 10.1002/jev2.12404

Bae JH, Lee CH, Jung D, Yea K, Song BJ, Lee H, Baek MC Extracellular vesicle isolation and counting system (EVics) based on simultaneous tandem tangential flow filtration and large field-of-view light scattering. J Extracell Vesicles. 2024;13(7):e12479 - PMID: 38978321 - PMCID: PMC11231039 - DOI: 10.1002/jev2.12479

Reynolds DE, Sun Y, Wang X, Vallapureddy P, Lim J, Pan M, Fernandez Del Castillo A, Carlson JCT, Sellmyer MA, Nasrallah M, Binder Z, O'Rourke DM, Ming GL, Song H, Ko J Live Organoid Cyclic Imaging. Adv Sci (Weinh). 2024;11(14):e2309289 - PMID: 38326078 - PMCID: PMC11005682 - DOI: 10.1002/advs.202309289

Enbergs N*, Halabi EA*, Goubet AG, Schleyer K, Fredrich IR, Kohler RH, Garris CS, Pittet MJ, Weissleder R Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Adv Sci (Weinh). 2024;11(15):e2309026 - PMID: 38342608 - PMCID: PMC11022742 - DOI: 10.1002/advs.202309026

Quintana JM, Kang M, Hu H, Ng TSC, Wojtkiewicz GR, Scott E, Parangi S, Schuemann J, Weissleder R, Miller MA Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation. ACS Cent Sci. 2024;10(7):1371-1382 - PMID: 39071065 - PMCID: PMC11273447 - DOI: 10.1021/acscentsci.4c00354

Kim HS, Halabi EA, Enbergs N, Kohler RH, Fei F, Garris CS, Weissleder R A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation. Theranostics. 2024;14(7):2934-2945 - PMID: 38773971 - PMCID: PMC11103498 - DOI: 10.7150/thno.95267

Das R, Ge X, Fei F, Parvanian S, Weissleder R*, Garris CS* Lipid Nanoparticle-mRNA Engineered Dendritic Cell Based Adoptive Cell Therapy Enhances Cancer Immune Response. Small Methods. 2024;:e2400633 - PMID: 39039995 - DOI: 10.1002/smtd.202400633

Conedera FM, Kokona D, Zinkernagel MS, Stein JV, Lin CP, Alt C, Enzmann V Macrophages coordinate immune response to laser-induced injury via extracellular traps. J Neuroinflammation. 2024;21(1):68 - PMID: 38500151 - PMCID: PMC10949579 - DOI: 10.1186/s12974-024-03064-0

Arai MS, Kim H, Pascavis M, Cha B, Brambilla G, Cho YK, Park J, Vilela RRC, de Camargo ASS, Castro CM, Lee H Upconverting Nanoparticle-based Enhanced Luminescence Lateral-Flow Assay for Urinary Biomarker Monitoring. ACS Appl Mater Interfaces. 2024;16(29):38243-38251 - PMID: 38980927 - DOI: 10.1021/acsami.4c06117

You DG, Jung JM, Kim CH, An JY, Bui VD, Lee J, Um W, Jo DG, Cho YW, Lee DS, Balaj L, Lee H, Park JH Stem Cell-Derived Extracellular Vesicle-Bearing Injectable Hydrogel for Collagen Generation in Dermis. ACS Appl Mater Interfaces. 2024;16(29):37698-37706 - PMID: 38980897 - DOI: 10.1021/acsami.4c07434

Gopal AA, Fernandez B, Delano J, Weissleder R, Dubach JM PARP trapping is governed by the PARP inhibitor dissociation rate constant. Cell Chem Biol. 2024;31(7):1373-1382.e10 - PMID: 38262416 - PMCID: PMC11259578 - DOI: 10.1016/j.chembiol.2023.12.019

Ichikawa S, Payne NC, Xu W, Chang CF, Vallavoju N, Frome S, Flaxman HA, Mazitschek R, Woo CM The cyclimids: Degron-inspired cereblon binders for targeted protein degradation. Cell Chem Biol. 2024;31(6):1162-1175.e10 - PMID: 38320555 - DOI: 10.1016/j.chembiol.2024.01.003

Timms L, Zhou T, Qiao J, Gharagouzloo C, Mishra V, Lahoud RM, Chen JW, Harisinghani M, Sridhar S Super High Contrast USPIO-Enhanced Cerebrovascular Angiography Using Ultrashort Time-to-Echo MRI. Int J Biomed Imaging. 2024;2024:9763364 - PMID: 38644981 - PMCID: PMC11032209 - DOI: 10.1155/2024/9763364

Sarkar B, Arlauckas SP, Cuccarese MF, Garris CS, Weissleder R, Rodell CB Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype Frontiers in Immunology (molecular innate immunity section). 2024;15:1331480 - PMID: 38545103 - PMCID: PMC10965546 - DOI: 10.3389/fimmu.2024.1331480

Banla LI, Hwang WL, Willers H The R's of Radiation Therapy: Do We Need More or Do We Move On? Int J Radiat Oncol Biol Phys. 2024;119(3):734-736 - PMID: 38851274 - DOI: 10.1016/j.ijrobp.2024.02.008

Chen SY, Kung HC, Espinoza B, Washington I, Chen K, Wang J, Zlomke H, Loycano MA, Wang R, Pickup M, Burns Iii WR, Fu J, Hwang WL, Zheng L Targeting heterogeneous tumor microenvironments in pancreatic cancer mouse models of metastasis by TGFβ depletion. JCI Insight. 2024;:ePub - PMID: 39298276 - DOI: 10.1172/jci.insight.182766

Jeng-Miller KW, Miller MA, Heier JS Ocular Effects of MEK Inhibitor Therapy: Literature Review, Clinical Presentation, and Best Practices for Mitigation. Oncologist. 2024;29(5):e616-e621 - PMID: 38527005 - PMCID: PMC11067803 - DOI: 10.1093/oncolo/oyae014

van Solinge TS, Oh J, Abels E, Koch P, Breakefield XO, Weissleder R, Broekman MLD Probing the glioma micro-environment: analysis using biopsy in combination with ultra-fast cyclic immunolabeling. Neoplasia. 2024;57:101051 - PMID: 39270598 - DOI: 10.1016/j.neo.2024.101051

Quintana JM, Carlson JCT, Scott E, Ng TSC, Miller MA, Weissleder R Scission-Enhanced Molecular Imaging (SEMI). Bioconjug Chem. 2024;:ePub - PMID: 39255972 - DOI: 10.1021/acs.bioconjchem.4c00337

Richardson DL, Moore KN, Vergote I, Gilbert L, Martin LP, Mantia-Smaldone GM, Castro CM, Provencher D, Matulonis UA, Stec J, Wang Y, Method M, O'Malley DM Phase 1b study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate, in combination with carboplatin and bevacizumab in patients with platinum-sensitive ovarian cancer. Gynecol Oncol. 2024;185:186-193 - PMID: 38447347 - DOI: 10.1016/j.ygyno.2024.01.045

Rosenthal ZC, Fass DM, Payne NC, She A, Patnaik D, Hennig KM, Tesla R, Werthmann GC, Guhl C, Reis SA, Wang X, Chen Y, Placzek M, Williams NS, Hooker J, Herz J, Mazitschek R, Haggarty SJ Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia. Sci Rep. 2024;14(1):9064 - PMID: 38643236 - PMCID: PMC11032351 - DOI: 10.1038/s41598-024-59110-7

McCullar KS, Abbaspour S, Wang W, Aguirre AD, Westover MB, Klerman EB Timing of diuretic administration effects on urine volume in hospitalized patients. Front Physiol. 2024;14:1208324 - PMID: 38321985 - PMCID: PMC10844419 - DOI: 10.3389/fphys.2023.1208324

Trinh K, Chow DZ, Park H, Habib U, Offit L, Franquet E, Almeida RR, Wang Y, Borges N, Jamal F, Jacene HA, Heidari P, Ng TSC Evaluating the added value of concurrent contrast-enhanced diagnostic CT for PSMA-PET/CT Interpretation. Acad Radiol. 2024;:ePub - PMID: 39147641 - DOI: 10.1016/j.acra.2024.08.008

Schleyer K, Halabi EA, Weissleder R γ-Butyrolactone derivatives of MSA-2 are STING prodrugs ChemMedChem. 2024;:e202400416 - PMID: 38887174 - DOI: 10.1002/cmdc.202400416

Kim JJ, Hong JS, Kim H, Choi M, Winter U, Lee H, Im H CRISPR/Cas13a-assisted amplification-free miRNA biosensor via dark-field imaging and magnetic gold nanoparticles. Sens Diagn. 2024;3(8):1310-1318 - PMID: 39129860 - PMCID: PMC11308380 - DOI: 10.1039/d4sd00081a

Owokuhaisa J, Turyakira E, Ssedyabane F, Tusubira D, Kajabwangu R, Musinguzi P, Galiwango M, Randall TC, Kakongi N, Castro CM, Atukunda EC, Maling S Barriers and facilitators of retention in care after cervical cancer screening: patients' and healthcare providers' perspectives. BMC Womens Health. 2024;24(1):516 - PMID: 39272088 - PMCID: PMC11401415 - DOI: 10.1186/s12905-024-03343-1

Lee G, Kim DW, Smart AC, Horick NK, Eyler CE, Roberts HJ, Pathak P, Goyal L, Franses J, Heather JM, Hwang WL, Grassberger C, Klempner SJ, Drapek LC, Allen JN, Blaszkowsky LS, Parikh AR, Ryan DP, Clark JW, Hong TS, Wo JY Hypofractionated Radiotherapy-Related Lymphopenia Is Associated With Worse Survival in Unresectable Intrahepatic Cholangiocarcinoma. Am J Clin Oncol. 2024;47(8):373-382 - PMID: 38767086 - DOI: 10.1097/COC.0000000000001108

Ssedyabane F, Niyonzima N, Nambi Najjuma J, Birungi A, Atwine R, Tusubira D, Randall TC, Castro CM, Lee H, Ngonzi J Prevalence of cervical intraepithelial lesions and associated factors among women attending a cervical cancer clinic in Western Uganda; results based on Pap smear cytology. SAGE Open Med. 2024;12:20503121241252265 - PMID: 38764539 - PMCID: PMC11100407 - DOI: 10.1177/20503121241252265

Parsi S, Zhu C, Motlagh NJ, Kim D, Küllenberg EG, Kim HH, Gillani RL, Chen JW Basic Science of Neuroinflammation and Involvement of the Inflammatory Response in Disorders of the Nervous System. Magn Reson Imaging Clin N Am. 2024;32(2):375-384 - PMID: 38555147 - PMCID: PMC10987041 - DOI: 10.1016/j.mric.2024.01.003

Ssedyabane F, Obuku EA, Namisango E, Ngonzi J, Castro CM, Lee H, Randall TC, Ocan M, Apunyo R, Annet Kinengyere A, Kajabwangu R, Tahirah Kisawe A, Nambi Najjuma J, Tusubira D, Niyonzima N The diagnostic accuracy of serum and plasma microRNAs in detection of cervical intraepithelial neoplasia and cervical cancer: A systematic review and meta-analysis. Gynecol Oncol Rep. 2024;54:101424 - PMID: 38939506 - PMCID: PMC11208915 - DOI: 10.1016/j.gore.2024.101424

Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N Asymmetric Engagement of Dimeric CRL3 ^KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes. bioRxiv. 2024;:ePub - PMID: 38798619 - PMCID: PMC11118476 - DOI: 10.1101/2024.05.14.593897

Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. bioRxiv. 2024;:ePub - PMID: 38798357 - PMCID: PMC11118371 - DOI: 10.1101/2024.05.14.593970

Payne NC, Ichikawa S, Woo CM, Mazitschek R Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology. STAR Protoc. 2024;5(2):103129 - PMID: 38857155 - PMCID: PMC11193044 - DOI: 10.1016/j.xpro.2024.103129

Petrozziello T, Motlagh NJ, Monsanto RZB, Lei D, Murcar MG, Penney EB, Bragg DC, Fernandez-Cerado C, Legarda GP, Sy M, Muñoz E, Ang MC, Diesta CCE, Zhang C, Tanzi RE, Qureshi IA, Chen JW, Sadri-Vakili G Targeting myeloperoxidase to reduce neuroinflammation in X-linked dystonia parkinsonism. medRxiv. 2024;:ePub - PMID: 38978657 - PMCID: PMC11230314 - DOI: 10.1101/2024.06.25.24309481

Momin N, Pabel S, Rudra A, Kumowski N, Lee IH, Mentkowski K, Yamazoe M, Stengel L, Muse CG, Seung H, Paccalet A, Gonzalez-Correa C, Jacobs EB, Grune J, Schloss MJ, Sossalla S, Wojtkiewicz G, Iwamoto Y, McMullen P, Mitchell RN, Ellinor PT, Anderson DG, Naxerova K, Nahrendorf M, Hulsmans M Therapeutic Spp1 silencing in TREM2 ⁺ cardiac macrophages suppresses atrial fibrillation. bioRxiv. 2024;:ePub - PMID: 39149373 - PMCID: PMC11326243 - DOI: 10.1101/2024.08.10.607461

Quintana JM, Jiang F, Kang M, Valladolid Onecha V, Könik A, Qin L, Rodriguez VE, Hu H, Borges N, Khurana I, Banla LI, Le Fur M, Caravan P, Schuemann J, Bertolet A, Weissleder R, Miller MA, Ng TSC Localized in vivo prodrug activation using radionuclides. bioRxiv. 2024;:ePub - PMID: 39211146 - PMCID: PMC11361159 - DOI: 10.1101/2024.08.02.606075