Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med. 2014;20(11):1301-9 - PMID: 25344738 - DOI: 10.1038/nm.3708
Harisinghani MG, Barentsz J, Hahn PF, Deserno WM, Tabatabaei S, van de Kaa CH, de la Rosette J, Weissleder R Noninvasive detection of clinically occult lymph-node metastases in prostate cancer N Engl J Med. 2003;348:2491-9 - PMID: 12815134 - DOI: 10.1056/NEJMoa022749
Merkel PA, McCarty D, Sharma A, Stone JR Case records of the Massachusetts General Hospital. Case 31-2008. A 39-year-old man with chest pain, arthralgias, and a mediastinal mass. N Engl J Med. 2008;359:1603-14 - PMID: 18843125 - DOI: 10.1056/NEJMcpc0805310
Brass SD, Durand ML, Stone JH, Chen JW, Stone JR Case records of the Massachusetts General Hospital. Case 36-2008. A 59-year-old man with chronic daily headache. N Engl J Med. 2008;359(21):2267-78 - PMID: 19020329 - DOI: 10.1056/NEJMcpc0805313
Kaufman DS, McDougal WS, Harisinghani MG, Wu CL Case records of the Massachusetts General Hospital. Case 30-2009. A 77-year-old man with recurrent transitional-cell carcinoma of the ureter. N Engl J Med. 2009;361(13):1292-9 - PMID: 19776411 - DOI: 10.1056/NEJMcpc0900642
Stone JH, Papaliodis GN, Dunbar MR, Stone JR Case 4-2010 -- a 53-year-old man with arthralgias, oral ulcers, vision loss, and vocal-cord paralysis. N Engl J Med. 2010;362(6):537-46 - PMID: 20147720 - DOI: 10.1056/NEJMcpc0910090
Ng AK, Abramson JS, Digumarthy SR, Reingold JS, Stone JR Case 24-2010. N Engl J Med. 2010;363(7):664-675 - PMID: 20818858 - DOI: 10.1056/NEJMcpc1004087
Sabatine MS, Jaffer FA, Staats PN, Stone JR Case records of the Massachusetts General Hospital. Case 28-2010. A 32-year-old woman, 3 weeks post partum, with substernal chest pain. N Engl J Med. 2010;363(12):1164-73 - PMID: 20843252 - DOI: 10.1056/NEJMcpc1000966
Karchmer AW, MacGillivray TE, Healey TT, Stone JR Case records of the Massachusetts General Hospital. Case 1-2011. A 35-year-old man with fever, bacteremia, and a mass in the left atrium. N Engl J Med. 2011;364(2):158-66 - PMID: 21226582 - DOI: 10.1056/NEJMcpc1004362
Kaufman DS, Zietman AL, Dahl DM, Harisinghani MG, Wu CL Case records of the Massachusetts General Hospital. Case 5-2011. A 65-year-old man with hematuria after treatment for prostate cancer. N Engl J Med. 2011;364(7):667-75 - PMID: 21323545 - DOI: 10.1056/NEJMcpc1005310
Kaufman DS, Zietman AL, McDougal WS, Dahl DM, Harisinghani MG, Wu CL Case records of the Massachusetts General Hospital. Case 9-2012. A 67-year-old man with a persistently elevated PSA level. N Engl J Med. 2012;366(12):1143-50 - PMID: 22435374 - DOI: 10.1056/NEJMcpc1104320
Bazari H, Guimaraes AR, Kushner YB Case records of the Massachusetts General Hospital. Case 20-2012. A 77-year-old man with leg edema, hematuria, and acute renal failure. N Engl J Med. 2012;366(26):2503-15 - PMID: 22738101 - DOI: 10.1056/NEJMcpc1111577
Hunt DP, Becker AE, Guimaraes AR, Stemmer-Rachamimov A, Misdraji J Case records of the Massachusetts General Hospital. Case 21-2012. A 27-year-old man with fatigue, weakness, weight loss, and decreased libido. N Engl J Med. 2012;367(2):157-69 - PMID: 22784119 - DOI: 10.1056/NEJMcpc1110053
Zella GC, Gee MS, Badizadegan K Case records of the Massachusetts General Hospital. Case 25-2012. A 15-year-old boy with abdominal pain, hematochezia, and anemia. N Engl J Med. 2012;367(7):659-67 - PMID: 22894579 - DOI: 10.1056/NEJMcpc1111578
Stone JH, Patel VI, Oliveira GR, Stone JR Case 38-2012. N Engl J Med. 2012;367(24):2335-46 - PMID: 23234517 - DOI: 10.1056/NEJMcpc1209330
Steele DJ, Kasmar AG, Guimaraes AR, Dekker JP Case records of the Massachusetts General Hospital. Case 3-2013. A 72-year-old woman with abdominal pain and distention after peritoneal dialysis. N Engl J Med. 2013;368(4):375-85 - PMID: 23343067 - DOI: 10.1056/NEJMcpc1208142
Simmons LH, Guimaraes AR, Zukerberg LR Case 6-2013. N Engl J Med. 2013;368(8):757-65 - PMID: 23425169 - DOI: 10.1056/NEJMcpc1208149
Awad MM, Katayama R, McTigue M, Liu W, Deng YL, Brooun A, Friboulet L, Huang D, Falk MD, Timofeevski S, Wilner KD, Lockerman EL, Khan TM, Mahmood S, Gainor JF, Digumarthy SR, Stone JR, Mino-Kenudson M, Christensen JG, Iafrate AJ, Engelman JA, Shaw AT Acquired Resistance to Crizotinib from a Mutation in CD74-ROS1. N Engl J Med. 2013;368(25):2395-401 - PMID: 23724914 - PMCID: PMC3878821 - DOI: 10.1056/NEJMoa1215530
Olumi AF, Kaufman DS, Zietman A, Harisinghani MG, Wu CL Case records of the Massachusetts General Hospital. Case 25-2013. A 71-year-old man with hematuria and a mass in the bladder. N Engl J Med. 2013;369(7):660-7 - PMID: 23944304 - DOI: 10.1056/NEJMcpc1209278
Baggett MV, Turbett SE, Schwartzenberg SS, Stone JR Case records of the Massachusetts General Hospital: Case 5-2014: 2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure. N Engl J Med. 2014;370(7):651-60 - PMID: 24521112 - DOI: 10.1056/NEJMcpc1310004
Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, Kinnunen L, Koistinen HA, Ladenvall C, Getz G, Correa A, Banahan BF, Gabriel S, Kathiresan S, Stringham HM, McCarthy MI, Boehnke M, Tuomilehto J, Haiman C, Groop L, Atzmon G, Wilson JG, Neuberg D, Altshuler D, Ebert BL Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes. N Engl J Med. 2014;371(26):2488-2498 - PMID: 25426837 - PMCID: PMC4306669 - DOI: 10.1056/NEJMoa1408617
Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T Restoration of p53 function leads to tumour regression in vivo. Nature. 2007;445:661-5 - PMID: 17251932 - DOI: 10.1038/nature05541
Weissleder R, Pittet MJ Imaging in the era of molecular oncology Nature. 2008;452:580-589 - PMID: 18385732 - PMCID: PMC2708079 - DOI: 10.1038/nature06917
Celso CL, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Cote D, Rowe DW, Lin CP, Scadden DT. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276 - DOI: 10.1038/nature07434
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH HDAC2 negatively regulates memory formation and synaptic plasticity. Nature. 2009;459(7243):55-60 - PMID: 19424149 - PMCID: PMC3498958 - DOI: 10.1038/nature07925
Mikkelsen T, Ku M, Jaffe D, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim T, Koche R, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, Xie X, Meissner A, Wernig M, Jaenisch R, Nusbaum C, Lander E, Bernstein B Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 2007;448(7153):553-60 - PMID: 17603471 - PMCID: PMC2921165 - DOI: 10.1038/nature06008
Sipkins DA, Wei X, Wu JW, Runnels JM, Cote D, Means TK, Luster AD, Scadden DT, Lin CP In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment. Nature. 2005;435:969-73 - PMID: 15959517 - PMCID: PMC2570168 - DOI: 10.1038/nature03703
Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow. Nature. 2009;459(7243):103-7 - PMID: 19322176 - PMCID: PMC2761017 - DOI: 10.1038/nature07859
Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, C Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276 - DOI: 10.1038/nature07434
Sachidanandam R, Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G, Sherry S, Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning Z, Rogers J, Bentley DR, Kwok PY, Mardis ER, Yeh RT, Schultz B, Cook L, Davenport R, Dante M, Fulton L, Hillier L, Waterston RH, McPherson JD, Gilman B, Schaffner S, Van Etten WJ, Reich D, Higgins J, Daly MJ, Blumenstiel B, Baldwin J, Stange-Thomann N, Zody MC, Linton L, Lander ES, Altshuler D, A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature. 2001;409(6822):928-33 - PMID: 11237013 - DOI: 10.1038/35057149
Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, Schaffner SF, Gabriel SB, Platko JV, Patterson NJ, McDonald GJ, Ackerman HC, Campbell SJ, Altshuler D, Cooper R, Kwiatkowski D, Ward R, Lander ES Detecting recent positive selection in the human genome from haplotype structure. Nature. 2002;419(6909):832-7 - PMID: 12397357 - DOI: 10.1038/nature01140
Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ Epigenetic memory in induced pluripotent stem cells. Nature. 2010;467(7313):285-90 - PMID: 20644535 - PMCID: PMC3150836 - DOI: 10.1038/nature09342
Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G, Golub TR Initial genome sequencing and analysis of multiple myeloma. Nature. 2011;471(7339):467-72 - PMID: 21430775 - PMCID: PMC3560292 - DOI: 10.1038/nature09837
Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE Mapping and analysis of chromatin state dynamics in nine human cell types. Nature. 2011;473(7345):43-9 - PMID: 21441907 - PMCID: PMC3088773 - DOI: 10.1038/nature09906
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Celso CL, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP In vivo imaging of T(reg) cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 2011;474(7350):216-9 - PMID: 21654805 - PMCID: PMC3725645 - DOI: 10.1038/nature10160
Dutta P*, Courties G*, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AN, Niessen HWM, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M Myocardial infarction accelerates atherosclerosis Nature. 2012;487(7407):325-9 - PMID: 22763456 - PMCID: PMC3401326 - DOI: 10.1038/nature11260
Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, Estrov Z, Ebert BL, Chiosis G, Nimer SD, Bernstein BE, Verstovsek S, Levine RL Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy. Nature. 2012;489(7414):155-9 - PMID: 22820254 - PMCID: PMC3991463 - DOI: 10.1038/nature11303
ENCODE Project Consortium, Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489(7414):57-74 - PMID: 22955616 - PMCID: PMC3439153 - DOI: 10.1038/nature11247
Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013;500(7463):477-81 - PMID: 23925113 - PMCID: PMC3821869 - DOI: 10.1038/nature12433
Tata PR, Mou H, Pardo-Saganta A, Zhao R, Prabhu M, Law BM, Vinarsky V, Cho JL, Breton S, Sahay A, Medoff BD, Rajagopal J Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature. 2013;503(7475):218-23 - PMID: 24196716 - PMCID: PMC4035230 - DOI: 10.1038/nature12777
Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, Bernstein BE, Kellis M, Regev A, Rinn JL, Lander ES Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 2009;458(7235):223-7 - PMID: 19182780 - PMCID: PMC2754849 - DOI: 10.1038/nature07672
Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 2008;454(7205):766-70 - PMID: 18600261 - PMCID: PMC2896277 - DOI: 10.1038/nature07107
Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A Dissecting direct reprogramming through integrative genomic analysis. Nature. 2008;454(7200):49-55 - PMID: 18509334 - PMCID: PMC2754827 - DOI: 10.1038/nature07056
Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Côté D, Vinogradov SA, Scadden DT, Lin CP Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature. 2014;508(7495):269-73 - PMID: 24590072 - PMCID: PMC3984353 - DOI: 10.1038/nature13034
Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY ABCB5 is a limbal stem cell gene required for corneal development and repair. Nature. 2014;511(7509):353-7 - PMID: 25030174 - PMCID: PMC4246512 - DOI: 10.1038/nature13426
Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, De Jager PL, Kuchroo VK, Epstein CB, Daly MJ, Hafler DA, Bernstein BE Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature. 2014;518(7539):337-43 - PMID: 25363779 - PMCID: PMC4336207 - DOI: 10.1038/nature13835
Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cacchiarelli D, Tsankov AM, Epstein C, Rinn JL, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature. 2014;518(7539):355-9 - PMID: 25533951 - PMCID: PMC4336237 - DOI: 10.1038/nature13990
Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M Integrative analysis of 111 reference human epigenomes. Nature. 2015;518(7539):317-30 - PMID: 25693563 - PMCID: PMC4530010 - DOI: 10.1038/nature14248
Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature. 2015;529(7584):110-4 - PMID: 26700815 - PMCID: PMC4831574 - DOI: 10.1038/nature16490
Hwang WL, Deindl S, Harada BT, Zhuang X Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA. Nature. 2014;512(7513):213-7 - PMID: 25043036 - PMCID: PMC4134374 - DOI: 10.1038/nature13380
Ventura A, Young A, Winslow M, Lintault L, Meissner A, Erkeland S, Newman J, Bronson R, Crowley D, Stone J, Jaenisch R, Sharp P, Jacks T Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 2008;132(5):875-86 - PMID: 18329372 - PMCID: PMC2323338 - DOI: 10.1016/j.cell.2008.02.019
Shum WW, Da Silva N, McKee M, Smith PJ, Brown D, Breton S Transepithelial Projections from Basal Cells are Luminal Sensors in Pseudostratified Epithelia Cell. 2008;135:1108-17 - PMID: 19070580 - PMCID: PMC2646085 - DOI: 10.1016/j.cell.2008.10.020
Bernstein B, Meissner A, Lander E The mammalian epigenome. Cell. 2007;128(4):669-81 - PMID: 17320505 - DOI: 10.1016/j.cell.2007.01.033
Bernstein B, Mikkelsen T, Xie X, Kamal M, Huebert D, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber S, Lander E A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 2006;125(2):315-26 - PMID: 16630819 - DOI: 10.1016/j.cell.2006.02.041
Bernstein B, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey D, Huebert D, McMahon S, Karlsson E, Kulbokas E, Gingeras T, Schreiber S, Lander E Genomic maps and comparative analysis of histone modifications in human and mouse. Cell. 2005;120(2):169-81 - PMID: 15680324 - DOI: 10.1016/j.cell.2005.01.001
Schreiber S, Bernstein B Signaling network model of chromatin. Cell. 2002;111(6):771-8 - PMID: 12526804 - DOI: 10.1016/s0092-8674(02)01196-0
Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1alpha. Cell. 2010;140(2):280-293 - PMID: 20141841 - PMCID: PMC2821045 - DOI: 10.1016/j.cell.2009.12.041
Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains. Cell. 2011;144(4):513-25 - PMID: 21335234 - PMCID: PMC3572774 - DOI: 10.1016/j.cell.2011.01.020
Walhout AJM, Aebersold R, Meyer T, Bork P, Kirschner MW Systems Biology: What's the Next Challenge? Cell. 2011;144:6
Pittet MJ, Weissleder R Intravital imaging. Cell. 2011;147(5):983-91 - PMID: 22118457 - PMCID: PMC3824153 - DOI: 10.1016/j.cell.2011.11.004
Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells. Cell. 2011;147(7):1628-39 - PMID: 22196736 - PMCID: PMC3312319 - DOI: 10.1016/j.cell.2011.09.057
Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, Depinho RA Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism. Cell. 2012;149(3):656-70 - PMID: 22541435 - PMCID: PMC3472002 - DOI: 10.1016/j.cell.2012.01.058
Zullo JM, Demarco IA, Piqué-Regi R, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh H DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell. 2012;149(7):1474-87 - PMID: 22726435 - DOI: 10.1016/j.cell.2012.04.035
Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, Macdonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism. Cell. 2012;151(6):1185-99 - PMID: 23217706 - PMCID: PMC3526953 - DOI: 10.1016/j.cell.2012.10.047
Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues. Cell. 2013;152(3):642-54 - PMID: 23333102 - PMCID: PMC3563935 - DOI: 10.1016/j.cell.2012.12.033
Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, Guttman M, Epstein C, Park H, Kohlbacher O, Rinn J, Gnirke A, Lander ES, Bernstein BE, Meissner A Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells. Cell. 2013;153(5):1149-1163 - PMID: 23664763 - PMCID: PMC3709577 - DOI: 10.1016/j.cell.2013.04.037
Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, Kadri S, Tirosh I, Wortman I, Shalek AK, Rozenblatt-Rosen O, Regev A, Louis DN, Bernstein BE Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells. Cell. 2014;157(3):580-94 - PMID: 24726434 - PMCID: PMC4004670 - DOI: 10.1016/j.cell.2014.02.030
Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell. 2014;158(5):1110-22 - PMID: 25171411 - PMCID: PMC4149753 - DOI: 10.1016/j.cell.2014.07.013
Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis. Cell. 2015;160(6):1246-60 - PMID: 25748654 - PMCID: PMC4380877 - DOI: 10.1016/j.cell.2015.02.038
Liu J, Lee J, Salazar Hernandez MA, Mazitschek R, Ozcan U Treatment of obesity with celastrol. Cell. 2015;161(5):999-1011 - PMID: 26000480 - PMCID: PMC4768733 - DOI: 10.1016/j.cell.2015.05.011
Garris CS, Pittet MJ ER Stress in Dendritic Cells Promotes Cancer. Cell. 2015;161(7):1492-3 - PMID: 26091029 - DOI: 10.1016/j.cell.2015.06.006
Deindl S, Hwang WL, Hota SK, Blosser TR, Prasad P, Bartholomew B, Zhuang X ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps. Cell. 2013;152(3):442-52 - PMID: 23374341 - PMCID: PMC3647478 - DOI: 10.1016/j.cell.2012.12.040
Weissleder R Scaling down imaging: molecular mapping of cancer in mice Nat Rev Cancer. 2002;2:1-8 - PMID: 11902581 - DOI: 10.1038/nrc701
Weissleder R. Molecular Imaging in Cancer Science. 2006;312:1168-1171 - PMID: 16728630 - DOI: 10.1126/science.1125949
Shaw S, Wang J Knotting of a DNA chain during ring closure. Science. 1993;260(5107):533-6 - PMID: 8475384 - DOI: 10.1126/science.8475384
Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response. Science. 2009;324(5932):1334-1338 - PMID: 19498172 - PMCID: PMC2803727 - DOI: 10.1126/science.1172638
Swirski* FK, Nahrendorf* M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites Science. 2009;325 (5940):612-6 - PMID: 19644120 - PMCID: PMC2803111 - DOI: 10.1126/science.1175202
Chi A, Bernstein B Developmental biology. Pluripotent chromatin state. Science. 2009;323(5911):220-1 - PMID: 19131621 - PMCID: PMC4126799 - DOI: 10.1126/science.1166261
Huang D, Swanson E, Lin C, Schuman J, Stinson W, Chang W, Hee M, Flotte T, Gregory K, Puliafito C Optical coherence tomography. Science. 1991;254:1178-81 - PMID: 1957169 - PMCID: PMC4638169 - DOI: 10.1126/science.1957169
Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses. Science. 2009;326(5950):257-63 - PMID: 19729616 - PMCID: PMC2879337 - DOI: 10.1126/science.1179050
Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, Stamatoyannopoulos J, Mirny LA, Lander ES, Dekker J Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science. 2009;326(5950):289-93 - PMID: 19815776 - PMCID: PMC2858594 - DOI: 10.1126/science.1181369
Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D The structure of haplotype blocks in the human genome. Science. 2002;296(5576):2225-9 - PMID: 12029063 - DOI: 10.1126/science.1069424
Rauch PJ*, Chudnovskiy A*, Robbins CS*, Weber GF, Etzrodt M, Hilgendorf I, Tiglao E, Figueiredo JL, Iwamoto Y, Theurl I, Gorbatov R, Waring MT, Chicoine AT, Mouded M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK Innate Response Activator B Cells Protect Against Microbial Sepsis Science. 2012;335(6068):597-601 - PMID: 22245738 - PMCID: PMC3279743 - DOI: 10.1126/science.1215173
Ryan RJ, Bernstein BE Molecular biology. Genetic events that shape the cancer epigenome. Science. 2012;336(6088):1513-4 - PMID: 22723401 - DOI: 10.1126/science.1223730
Swirski FK, Nahrendorf M Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure. Science. 2013;339(6116):161-6 - PMID: 23307733 - PMCID: PMC3891792 - DOI: 10.1126/science.1230719
Suvà ML, Riggi N, Bernstein BE Epigenetic reprogramming in cancer. Science. 2013;339(6127):1567-70 - PMID: 23539597 - PMCID: PMC3821556 - DOI: 10.1126/science.1230184
Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, Eberl G, Bérard M, Ecobichon C, Clermont D, Bizet C, Gaboriau-Routhiau V, Cerf-Bensussan N, Opolon P, Yessaad N, Vivier E, Ryffel B, Elson CO, Doré J, Kroemer G, Lepage P, Boneca IG, Ghiringhelli F, Zitvogel L The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science. 2013;342(6161):971-6 - PMID: 24264990 - PMCID: PMC4048947 - DOI: 10.1126/science.1240537
Katsimpardi L, Litterman NK, Schein PA, Miller CM, Loffredo FS, Wojtkiewicz GR, Chen JW, Lee RT, Wagers AJ, Rubin LL Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors. Science. 2014;344(6184):630-4 - PMID: 24797482 - PMCID: PMC4123747 - DOI: 10.1126/science.1251141
Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science. 2014;344(6190):1396-401 - PMID: 24925914 - PMCID: PMC4123637 - DOI: 10.1126/science.1254257
Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, Klotzsche-von Ameln A, Chavakis T, Weitz J, Hofer S, Weigand MA, Nahrendorf M, Weissleder R, Swirski FK Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis. Science. 2015;347(6227):1260-1265 - PMID: 25766237 - PMCID: PMC4376966 - DOI: 10.1126/science.aaa4268
Nahrendorf M, Swirski FK Neutrophil-macrophage communication in inflammation and atherosclerosis. Science. 2015;349(6245):237-8 - PMID: 26185231 - DOI: 10.1126/science.aac7801
Perez JM, Josephson L, O'Loughlin T, Hogemann D, Weissleder R Magnetic relaxation switches capable of sensing molecular interactions Nat Biotechnol. 2002;20:816-20 - PMID: 12134166 - DOI: 10.1038/nbt720
Weissleder R A clearer vision for in vivo imaging Nat Biotechnol. 2001;19:316-7 - PMID: 11283581 - DOI: 10.1038/86684
Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells Nat Biotechnol. 2000;18:410-4 - PMID: 10748521 - DOI: 10.1038/74464
Weissleder R, Tung CH, Mahmood U, Bogdanov A Jr In vivo imaging of tumors with protease-activated near-infrared fluorescent probes Nat Biotechnol. 1999;17:375-8 - PMID: 10207887 - DOI: 10.1038/7933
Ntziachristos V, Ripoll J, Wang L, Weissleder R Looking and Listening to light: the evolution of whole-body photonic imaging Nat Biotechnol. 2005;23:313-320 - PMID: 15765087 - DOI: 10.1038/nbt1074
Weissleder R, Kelly K, Sun E, Shtatland T, Josephson L. Cell-specific targeting of nanoparticles by multivalent attachment of small molecules Nat Biotechnol. 2005;23:1418-1423 - PMID: 16244656 - DOI: 10.1038/nbt1159
Peterson R, Shaw S, Peterson T, Milan D, Zhong T, Schreiber S, MacRae C, Fishman M Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol. 2004;22(5):595-9 - PMID: 15097998 - DOI: 10.1038/nbt963
Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, Echipare L, O'Geen H, Lister R, Pelizzola M, Xi Y, Epstein CB, Bernstein BE, Hawkins RD, Ren B, Chung WY, Gu H, Bock C, Gnirke A, Zhang MQ, Haussler D, Ecker JR, Li W, Farnham PJ, Waterland RA, Meissner A, Marra MA, Hirst M, Milosavljevic A, Costello JF Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol. 2010;28(10):1097-105 - PMID: 20852635 - PMCID: PMC2955169 - DOI: 10.1038/nbt.1682
Bernstein BE, Stamatoyannopoulos JA, Costello JF, Ren B, Milosavljevic A, Meissner A, Kellis M, Marra MA, Beaudet AL, Ecker JR, Farnham PJ, Hirst M, Lander ES, Mikkelsen TS, Thomson JA The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol. 2010;28(10):1045-8 - PMID: 20944595 - PMCID: PMC3607281 - DOI: 10.1038/nbt1010-1045
Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M Therapeutic siRNA silencing in inflammatory monocytes in mice Nat Biotechnol. 2011;29(11):1005-10 - PMID: 21983520 - PMCID: PMC3212614 - DOI: 10.1038/nbt.1989
Mendenhall EM, Williamson KE, Reyon D, Zou JY, Ram O, Joung JK, Bernstein BE Locus-specific editing of histone modifications at endogenous enhancers. Nat Biotechnol. 2013;31(12):1133-6 - PMID: 24013198 - PMCID: PMC3858395 - DOI: 10.1038/nbt.2701
Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol. 2013;31(10):898-907 - PMID: 24013197 - PMCID: PMC4058317 - DOI: 10.1038/nbt.2682
Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nat Biotechnol. 2013;31(12):1137-42 - PMID: 24108092 - PMCID: PMC3858462 - DOI: 10.1038/nbt.2726
Im H*, Shao H*, Park YI, Peterson VM, Castro CM, Weissleder R*, Lee H* Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947 - DOI: 10.1038/nbt.2886
Rotem A, Ram O, Shoresh N, Sperling RA, Goren A, Weitz DA, Bernstein BE Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state. Nat Biotechnol. 2015;33(11):1165-72 - PMID: 26458175 - PMCID: PMC4636926 - DOI: 10.1038/nbt.3383
Lee H, Shin TH, Cheon J, Weissleder R Recent Developments in Magnetic Diagnostic Systems Chem Rev. 2015;115(19):10690-724 - PMID: 26258867 - PMCID: PMC5791529 - DOI: 10.1021/cr500698d
Tannous B*, Grimm J*, Perry K, Chen J, Weissleder R, Breakefield X. Metabolic Biotinylation of Cell Surface Receptors for in vivo Imaging Nat Methods. 2006;3(5):391-396 - PMID: 16628210 - DOI: 10.1038/nmeth875
Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nat Methods. 2007;5(1):45-7 - PMID: 18066071 - DOI: 10.1038/nmeth1149
Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods. 2008;5:171-173 - PMID: 18204457 - PMCID: PMC2699561 - DOI: 10.1038/nmeth.1177
Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA. Nat Methods. 2009;7(1):47-9 - PMID: 19946276 - PMCID: PMC2862482 - DOI: 10.1038/nmeth.1404
Adli M, Zhu J, Bernstein BE Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors. Nat Methods. 2010;7(8):615-8 - PMID: 20622861 - PMCID: PMC2924612 - DOI: 10.1038/nmeth.1478
Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R*, Danuser G*, Mitchison TJ* In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy Nat Methods. 2015;12(6):577-585 - PMID: 25867850 - PMCID: PMC4579269 - DOI: 10.1038/nmeth.3363
Glenn DR#, Lee K#, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H*, Walsworth RL*, Connolly CB* Single-cell magnetic imaging using a quantum diamond microscope. Nat Methods. 2015;12(8):736-738 - PMID: 26098019 - PMCID: PMC4521973 - DOI: 10.1038/nmeth.3449
Kong L, Tang J, Little JP, Yu Y, Lämmermann T, Lin CP, Germain RN, Cui M Continuous volumetric imaging via an optical phase-locked ultrasound lens. Nat Methods. 2015;12(8):759-762 - PMID: 26167641 - PMCID: PMC4551496 - DOI: 10.1038/nmeth.3476
Corsten MF, Shah K Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare. Lancet Oncol. 2008;9(4):376-84 - PMID: 18374291 - DOI: 10.1016/S1470-2045(08)70099-8
Harisinghani M Nanoparticle-enhanced MRI: are we there yet? Lancet Oncol. 2008;9(9):814-815 - PMID: 18760237 - DOI: 10.1016/S1470-2045(08)70215-8
Khosroshahi A, Stone JR, Pratt DS, Deshpande V, Stone JH Painless jaundice with serial multi-organ dysfunction. Lancet Oncol. 2009;373(9673):1494 - PMID: 19394539 - DOI: 10.1016/S0140-6736(09)60615-2
Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D Arthritis critically dependent on innate immune system players Immunity. 2002;16:157-68 - PMID: 11869678 - DOI: 10.1016/s1074-7613(02)00275-3
Mempel T, Pittet M, Khazaie K, Weninger W, Weissleder R, von Boehmer H, von Adrian U. Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation Immunity. 2006;25(1):129-41 - PMID: 16860762 - DOI: 10.1016/j.immuni.2006.04.015
Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, Mino-Kenudson M, Forghani R, Figueiredo JL, Chen JW, Xavier R, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ Angiotensin II Drives the Production of Tumor-Promoting Macrophages Immunity. 2013;38(2):296-308 - PMID: 23333075 - PMCID: PMC3582771 - DOI: 10.1016/j.immuni.2012.10.015
Bronte V, Pittet MJ The spleen in local and systemic regulation of immunity. Immunity. 2013;39(5):806-18 - PMID: 24238338 - PMCID: PMC3912742 - DOI: 10.1016/j.immuni.2013.10.010
Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005;37(7):739-44 - PMID: 15924139 - PMCID: PMC1360984 - DOI: 10.1038/ng1592
Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006;38(5):531-9 - PMID: 16604073 - DOI: 10.1038/ng1777
Andriopoulos Jr B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet. 2009;41(4):482-7 - PMID: 19252486 - PMCID: PMC2810136 - DOI: 10.1038/ng.335
Reich DE, Schaffner SF, Daly MJ, McVean G, Mullikin JC, Higgins JM, Richter DJ, Lander ES, Altshuler D Human genome sequence variation and the influence of gene history, mutation and recombination. Nat Genet. 2002;32(1):135-42 - PMID: 12161752 - DOI: 10.1038/ng947
Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, Gutierrez A, Stegmaier K, Kung AL, Root DE, Bradner JE, Aster JC, Kelliher MA, Bernstein BE An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia. Nat Genet. 2014;46(4):364-70 - PMID: 24584072 - PMCID: PMC4086945 - DOI: 10.1038/ng.2913
Zhou VW, Goren A, Bernstein BE Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet. 2010;12(1):7-18 - PMID: 21116306 - DOI: 10.1038/nrg2905
Stoeck A, Lejnine S, Truong A, Pan L, Wang H, Zang C, Yuan J, Ware C, MacLean J, Garrett-Engele PW, Kluk M, Laskey J, Haines BB, Moskaluk C, Zawel L, Fawell S, Gilliland G, Zhang T, Kremer B, Knoechel B, Bernstein BE, Pear WS, Liu XS, Aster JC, Sathyanarayanan S Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma. Cancer Discov. 2014;4(10):1154-67 - PMID: 25104330 - PMCID: PMC4184927 - DOI: 10.1158/2159-8290.CD-13-0830
Ryan RJ, Drier Y, Whitton H, Cotton MJ, Kaur J, Issner R, Gillespie S, Epstein CB, Nardi V, Sohani AR, Hochberg EP, Bernstein BE Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma. Cancer Discov. 2015;5(10):1058-71 - PMID: 26229090 - PMCID: PMC4592453 - DOI: 10.1158/2159-8290.CD-15-0370
Rabin O, Manuel Perez J, Grimm J, Wojtkiewicz G, Weissleder R An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nat Mater. 2006;5(2):118-22 - PMID: 16444262 - DOI: 10.1038/nmat1571
Weissleder R, Nahrendorf M, Pittet MJ Imaging macrophages with nanoparticles. Nat Mater. 2014;13(2):125-38 - PMID: 24452356 - DOI: 10.1038/nmat3780
Marten K, Bremer C, Khazaie K, Sameni M, Sloane B, Tung CH, Weissleder R Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice Gastroenterology. 2002;122:406-14 - PMID: 11832455 - DOI: 10.1053/gast.2002.30990
Mahmood U, Wallace MB Molecular imaging in gastrointestinal disease. Gastroenterology. 2007;132(1):11-4 - PMID: 17241854 - DOI: 10.1053/j.gastro.2006.12.013
Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity. Gastroenterology. 2008;134(4):1028-37 - PMID: 18395084 - DOI: 10.1053/j.gastro.2008.01.070
Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B, Lin HY, Pietrangelo A, Babitt JL Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis. Gastroenterology. 2009;137(4):1489-97 - PMID: 19591830 - PMCID: PMC2757523 - DOI: 10.1053/j.gastro.2009.06.057
Corradini E, Schmidt PJ, Meynard D, Garuti C, Montosi G, Chen S, Vukicevic S, Pietrangelo A, Lin HY, Babitt JL BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice. Gastroenterology. 2010;139(5):1721-9 - PMID: 20682319 - PMCID: PMC3295242 - DOI: 10.1053/j.gastro.2010.07.044
Parekkadan B, Upadhyay R, Dunham J, Iwamoto Y, Mizoguchi E, Mizoguchi A, Weissleder R, Yarmush ML Bone Marrow Stromal Cell Transplants Prevent Experimental Enterocolitis and Require Host CD11b+ Splenocytes. Gastroenterology. 2010;140(3):966-975.e4 - PMID: 20955701 - PMCID: PMC3033974 - DOI: 10.1053/j.gastro.2010.10.013
Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe. Gastroenterology. 2011;141(5):1907-14 - PMID: 21745449 - PMCID: PMC3634343 - DOI: 10.1053/j.gastro.2011.06.077
Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection. Gastroenterology. 2013;145(6):1347-57 - PMID: 23973919 - PMCID: PMC3840157 - DOI: 10.1053/j.gastro.2013.08.035
Rudin M, Weissleder R Molecular imaging in drug discovery and development Nat Rev Drug Discov. 2003;2:123-31 - PMID: 12563303 - DOI: 10.1038/nrd1007
Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection Nat Nanotechnol. 2010;5(9):660-5 - PMID: 20676091 - PMCID: PMC2934903 - DOI: 10.1038/nnano.2010.148
Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM Cell-surface sensors for real-time probing of cellular environments. Nat Nanotechnol. 2011;6(8):524-31 - PMID: 21765401 - PMCID: PMC3163485 - DOI: 10.1038/nnano.2011.101
Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat Nanotechnol. 2012;7(6):389-93 - PMID: 22659608 - PMCID: PMC3898745 - DOI: 10.1038/nnano.2012.73
Chung HJ, Castro CM, Im H, Lee H*, Weissleder R* A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria Nat Nanotechnol. 2013;8(5):369-75 - PMID: 23644570 - PMCID: PMC3711657 - DOI: 10.1038/nnano.2013.70
Dahlman JE, Barnes C, Khan O, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, Jiang S, Seedorf D, Dave A, Sandu KS, Webber MJ, Novobrantseva T, Ruda VM, Lytton-Jean AK, Levins CG, Kalish B, Mudge DK, Perez M, Abezgauz L, Dutta P, Smith L, Charisse K, Kieran MW, Fitzgerald K, Nahrendorf M, Danino D, Tuder RM, von Andrian UH, Akinc A, Panigrahy D, Schroeder A, Kotelianski V, Langer R, Anderson DG In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nat Nanotechnol. 2014;9(8):648-55 - PMID: 24813696 - PMCID: PMC4207430 - DOI: 10.1038/nnano.2014.84
Im H, Huang XJ, Gu B, Choi YK A dielectric-modulated field-effect transistor for biosensing. Nat Nanotechnol. 2007;2(7):430-4 - PMID: 18654328 - DOI: 10.1038/nnano.2007.180
Maglia G, Heron AJ, Hwang WL, Holden MA, Mikhailova E, Li Q, Cheley S, Bayley H Droplet networks with incorporated protein diodes show collective properties. Nat Nanotechnol. 2009;4(7):437-40 - PMID: 19581896 - DOI: 10.1038/nnano.2009.121
Jaffer F, Weissleder R Molecular Imaging in the Clinical Arena JAMA. 2005;293(7):855-62 - PMID: 15713776 - DOI: 10.1001/jama.293.7.855
Min JK, Leipsic J, Pencina MJ, Berman DS, Koo BK, van Mieghem C, Erglis A, Lin FY, Dunning AM, Apruzzese P, Budoff MJ, Cole JH, Jaffer FA, Leon MB, Malpeso J, Mancini GB, Park SJ, Schwartz RS, Shaw LJ, Mauri L Diagnostic Accuracy of Fractional Flow Reserve From Anatomic CT Angiography. JAMA. 2012;308(12):1237-45 - PMID: 22922562 - PMCID: PMC4281479 - DOI: 10.1001/2012.jama.11274
Langer R, Weissleder R Nanotechnology. JAMA. 2015;313(2):135-136 - PMID: 25585320 - DOI: 10.1001/jama.2014.16315
Xing M, Alzahrani AS, Carson KA, Viola D, Elisei R, Bendlova B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L, Czarniecka A, Jarzab B, O'Neill CJ, Sywak MS, Lam AK, Riesco-Eizaguirre G, Santisteban P, Nakayama H, Tufano RP, Pai SI, Zeiger MA, Westra WH, Clark DP, Clifton-Bligh R, Sidransky D, Ladenson PW, Sykorova V Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. JAMA. 2013;309(14):1493-501 - PMID: 23571588 - PMCID: PMC3791140 - DOI: 10.1001/jama.2013.3190
Nahrendorf M, Aikawa E, Figueiredo JL, Stangenberg L, van den Borne S, Blankesteijn M, Sosnovik D, Jaffer F, Tung CH, Weissleder R Transglutaminase activity in acute infarcts predicts healing outcome and let ventricular remodelling : implications for FXIII therapy and antithrombin use in myocardial infarction Eur Heart J. 2008;29:445-454 - PMID: 18276618 - DOI: 10.1093/eurheartj/ehm558
Matter CM, Stuber M, Nahrendorf M Imaging of the unstable plaque: how far have we got? Eur Heart J. 2009;30(21):2566-74 - PMID: 19833636 - PMCID: PMC2771148 - DOI: 10.1093/eurheartj/ehp419
Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation. Eur Heart J. 2010;31(16):1975-84 - PMID: 20601388 - PMCID: PMC2921509 - DOI: 10.1093/eurheartj/ehq237
van der Laan AM, Ter Horst EN, Delewi R, Begieneman MP, Krijnen PA, Hirsch A, Lavaei M, Nahrendorf M, Horrevoets AJ, Niessen HW, Piek JJ Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir. Eur Heart J. 2013;35(6):376-85 - PMID: 23966310 - PMCID: PMC3916776 - DOI: 10.1093/eurheartj/eht331
Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014;35(42):2972-9 - PMID: 24742886 - PMCID: PMC4223610 - DOI: 10.1093/eurheartj/ehu153
Leuschner F, Courties G, Dutta P, Mortensen LJ, Gorbatov R, Sena B, Novobrantseva TI, Borodovsky A, Fitzgerald K, Koteliansky V, Iwamoto Y, Bohlender M, Meyer S, Lasitschka F, Meder B, Katus HA, Lin C, Libby P, Swirski FK, Anderson DG, Weissleder R, Nahrendorf M Silencing of CCR2 in myocarditis. Eur Heart J. 2014;36(23):1478-88 - PMID: 24950695 - PMCID: PMC4465633 - DOI: 10.1093/eurheartj/ehu225
Nahrendorf M, Swirski FK Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction Eur Heart J. 2015;37(11):868-72 - PMID: 26351395 - PMCID: PMC4789592 - DOI: 10.1093/eurheartj/ehv453
Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo. Eur Heart J. 2015;38(6):447-455 - PMID: 26685129 - PMCID: PMC5837565 - DOI: 10.1093/eurheartj/ehv677
Weissleder R, Ntziachristos V Shedding light onto live molecular targets Nature Med. 2003;9:123-8 - PMID: 12514725 - DOI: 10.1038/nm0103-123
Ntziachristos V, Tung CH, Bremer C, Weissleder R Fluorescence molecular tomography resolves protease activity in vivo Nature Med. 2002;8:757-60 - PMID: 12091907 - DOI: 10.1038/nm729
Bremer C, Tung CH, Weissleder R In vivo molecular target assessment of matrix metalloproteinase inhibition Nature Med. 2001;7:743-8 - PMID: 11385514 - DOI: 10.1038/89126
Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP In vivo magnetic resonance imaging of transgene expression Nature Med. 2000;6:351-5 - PMID: 10700241 - DOI: 10.1038/73219
Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T A spatially and temporally restricted mouse model of soft tissue sarcoma. Nature Med. 2007;13(8):992-997 - PMID: 17676052 - DOI: 10.1038/nm1602
Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nature Med. 2008;14(2):181-7 - PMID: 18193058 - DOI: 10.1038/nm1703
Kaushal S, Amiel G, Guleserian K, Shapira O, Perry T, Sutherland F, Rabkin E, Moran A, Schoen F, Atala A, Soker S, Bischoff J, Mayer J Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nature Med. 2001;7:1035-40 - PMID: 11533707 - PMCID: PMC2818999 - DOI: 10.1038/nm0901-1035
Shimizu K, Sugiyama S, Aikawa M, Fukumoto Y, Rabkin E, Libby P, Mitchell R Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy. Nature Med. 2001;7:738-41 - PMID: 11385513 - DOI: 10.1038/89121
Lee H, Sun E, Ham D, Weissleder R Chip-NMR biosensor for detection and molecular analysis of cells. Nature Med. 2008;14(8):869-74 - PMID: 18607350 - PMCID: PMC2729055 - DOI: 10.1038/nm.1711
Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, Garcia-Echeverria C, Weissleder R, Mahmood U, Cantley LC, Wong KK Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nature Med. 2008;14(12)::1351-1356 - PMID: 19029981 - PMCID: PMC2683415 - DOI: 10.1038/nm.1890
Dagia N, Gadhoum S, Knoblauch C, Spencer J, Zamiri P, Lin CP, Sackstein R G-CSF induces E-selectin ligand expression on human myeloid cells. Nature Med. 2006;12:1185-90 - PMID: 16980970 - DOI: 10.1038/nm1470
Fan Z, Spencer JA, Lu Y, Pitsillides CM, Singh G, Kim P, Yun SH, Toxavidis V, Strom TB, Lin CP, Koulmanda M In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response. Nature Med. 2010;16(6):718-22 - PMID: 20495571 - PMCID: PMC2894571 - DOI: 10.1038/nm.2155
Breton S, Smith PJ, Lui B, Brown D Acidification of the male reproductive tract by a proton pumping (H+)-ATPase. Nature Med. 1996;2(4):470-2 - PMID: 8597961 - DOI: 10.1038/nm0496-470
Panizzi P*, Nahrendorf M*, Jose-Luiz Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, Fuentes-Prior P, Schneewind O, Bock PE, Weissleder R In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation Nature Med. 2011;17(9):1142-6 - PMID: 21857652 - PMCID: PMC3169740 - DOI: 10.1038/nm.2423
Yoo H, Kim JW, Shishkov M, Namati E, Morse T, Shubochkin R, McCarthy JR, Ntziachristos V, Bouma BE, Jaffer FA, Tearney GJ Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo. Nature Med. 2011;17(12):1680-4 - PMID: 22057345 - PMCID: PMC3233646 - DOI: 10.1038/nm.2555
Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, Hochberg FH, Breakefield XO, Weissleder R*, Lee H* Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy Nature Med. 2012;18(12):1835-1840 - PMID: 23142818 - PMCID: PMC3518564 - DOI: 10.1038/nm.2994
Robbins CS, Hilgendorf I, Weber GF, Theurl I, Iwamoto Y, Figueiredo JL, Gorbatov R, Sukhova GK, Gerhardt LM, Smyth D, Zavitz CC, Shikatani EA, Parsons M, Rooijen NV, Lin HY, Husain M, Libby P, Nahrendorf M, Weissleder R, Swirski FK Local proliferation dominates lesional macrophage accumulation in atherosclerosis Nature Med. 2013;19(9):1166-72 - PMID: 23933982 - PMCID: PMC3769444 - DOI: 10.1038/nm.3258
Garris C, Pittet MJ Therapeutically reeducating macrophages to treat GBM. Nature Med. 2013;19(10):1207-1208 - PMID: 24100977 - DOI: 10.1038/nm.3355
Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nature Med. 2013;19(11):1513-7 - PMID: 24162813 - PMCID: PMC3827980 - DOI: 10.1038/nm.3364
Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M Chronic variable stress activates hematopoietic stem cells Nature Med. 2014;20(7):754-758 - PMID: 24952646 - PMCID: PMC4087061 - DOI: 10.1038/nm.3589
Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R In vivo imaging of proteolytic activity in atherosclerosis Circulation. 2002;105:2766-71 - PMID: 12057992 - DOI: 10.1161/01.cir.0000017860.20619.23
Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R Molecular Imaging of Factor XIIIa Activity in Thrombosis Using a Novel, Near-Infrared Fluorescent Contrast Agent That Covalently Links to Thrombi. Circulation. 2004;110(2):170-6 - PMID: 15210587 - DOI: 10.1161/01.CIR.0000134484.11052.44
Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL. Near-Infrared Fluorescent Imaging of Matrix Metalloproteinase Activity After Myocardial Infarction Circulation. 2005;111:1800-1805 - PMID: 15809374 - PMCID: PMC3733536 - DOI: 10.1161/01.CIR.0000160936.91849.9F
Nahrendorf M, Hu K, Frantz S, Jaffer F, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlohner S, Novikov M, Dickneite G, Reed G, Jakob P, Rosenzweig A, Bauer W, Weissleder R, Ertl G. Factor XIII Deficiency Causes Cardiac Rupture, Impairs Wound Healing, and Aggravates Cardiac Remodeling in Mice with Myocardial Infarction Circulation. 2006;113(9):1196-1202 - PMID: 16505171 - PMCID: PMC4066325 - DOI: 10.1161/CIRCULATIONAHA.105.602094
Heller EA, Liu E, Tager AM, Yuan Q, Lin AY, Ahluwalia N, Jones K, Koehn SL, Lok VM, Aikawa E, Moore KJ, Luster AD, Gerszten RE Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells. Circulation. 2006;113(19):2301-12 - PMID: 16682613 - DOI: 10.1161/CIRCULATIONAHA.105.605121
Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P Inflammation in Atherosclerosis. Visualizing Matrix Metalloproteinase Action in Macrophages In Vivo. Circulation. 2006;114:55-62 - PMID: 16801460 - DOI: 10.1161/CIRCULATIONAHA.106.619056
Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis. Circulation. 2006;114:1504-1511 - PMID: 17000904 - DOI: 10.1161/CIRCULATIONAHA.106.646380
Aikawa E, Nahrendorf M, Sosnovik D, Lok VM, Jaffer FA, Aikawa M, Weissleder R Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease. Circulation. 2007;115:377-386 - PMID: 17224478 - DOI: 10.1161/CIRCULATIONAHA.106.654913
Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V Fluorescence Tomography and Magnetic Resonance Imaging of Myocardial Macrophage Infiltration in Infarcted Myocardium In Vivo. Circulation. 2007;115:1384-1391 - PMID: 17339546 - DOI: 10.1161/CIRCULATIONAHA.106.663351
Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, Weissleder R Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor. Circulation. 2007;115(17):2292-8 - PMID: 17420353 - DOI: 10.1161/CIRCULATIONAHA.106.660340
Sosnovik DE, Nahrendorf M, Weissleder R Molecular magnetic resonance imaging in cardiovascular medicine. Circulation. 2007;115(15):2076-86 - PMID: 17438163 - DOI: 10.1161/CIRCULATIONAHA.106.658930
Jaffer FA, Libby P, Weissleder R Molecular imaging of cardiovascular disease. Circulation. 2007;116(9):1052-61 - PMID: 17724271 - DOI: 10.1161/CIRCULATIONAHA.106.647164
Aikawa E, Nahrendorf M, Figueiredo JL, Swirski F, Shtatland T, Kohler RH, Jaffer F, Aikawa M, Weissleder R. Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation. 2007;116(24):2841-50 - PMID: 18040026 - DOI: 10.1161/CIRCULATIONAHA.107.732867
Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik D, Aikawa E, Libby P, Swirski F, Weissleder R. Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis Circulation. 2007;117:379-387 - PMID: 18158358 - PMCID: PMC2663426 - DOI: 10.1161/CIRCULATIONAHA.107.741181
Kircher M, Grimm J, Swirski FK, Libby P, Gerszten R, Allport J, Weissleder R Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions. Circulation. 2008;117:388-395 - PMID: 18172031 - PMCID: PMC2705289 - DOI: 10.1161/CIRCULATIONAHA.107.719765
Nahrendorf M*, Sosnovik D*, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R Activatable Magnetic Resonance Imaging Agent Reports Myeloperoxidase Activity in Healing Infarcts and Noninvasively Detects the Antiinflammatory Effects of Atorvastatin on Ischemia-Reperfusion Injury. Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051 - DOI: 10.1161/CIRCULATIONAHA.107.756510
Libby P, Nahrendorf M, Pittet MJ, Swirski FK Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal. Circulation. 2008;117(25):3168-70 - PMID: 18574058 - DOI: 10.1161/CIRCULATIONAHA.108.783068
Aikawa E, Whittaker P, Farber M, Mendelson K, Padera R, Aikawa M, Schoen F Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation. 2006;113:1344-52 - PMID: 16534030 - DOI: 10.1161/CIRCULATIONAHA.105.591768
Aikawa M, Sugiyama S, Hill C, Voglic S, Rabkin E, Fukumoto Y, Schoen F, Witztum J, Libby P Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma. Circulation. 2002;106:1390-6 - PMID: 12221058 - DOI: 10.1161/01.cir.0000028465.52694.9b
Deguchi J, Aikawa E, Libby P, Vachon J, Inada M, Krane S, Whittaker P, Aikawa M Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques. Circulation. 2005;112:2708-15 - PMID: 16230484 - DOI: 10.1161/CIRCULATIONAHA.105.562041
Lindsey M, Gannon J, Aikawa M, Schoen F, Rabkin E, Lopresti-Morrow L, Crawford J, Black S, Libby P, Mitchell P, Lee R Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction. Circulation. 2002;105:753-8 - PMID: 11839633 - DOI: 10.1161/hc0602.103674
Larose E, Yeghiazarians Y, Libby P, Yucel E, Aikawa M, Kacher D, Aikawa E, Kinlay S, Schoen F, Selwyn A, Ganz P Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging. Circulation. 2005;112:2324-31 - PMID: 16203910 - DOI: 10.1161/CIRCULATIONAHA.105.538942
Heller E, Liu E, Tager A, Sinha S, Roberts J, Koehn S, Libby P, Aikawa E, Chen J, Huang P, Freeman M, Moore K, Luster A, Gerszten R Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation. 2005;112:578-86 - PMID: 16043658 - DOI: 10.1161/CIRCULATIONAHA.105.545616
Sutherland F, Perry T, Yu Y, Sherwood M, Rabkin E, Masuda Y, Garcia G, McLellan D, Engelmayr G, Sacks M, Schoen F, Mayer J From stem cells to viable autologous semilunar heart valve. Circulation. 2005;111:2783-91 - PMID: 15927990 - DOI: 10.1161/CIRCULATIONAHA.104.498378
Fukumoto Y, Deguchi J, Libby P, Rabkin-Aikawa E, Sakata Y, Chin M, Hill C, Lawler P, Varo N, Schoen F, Krane S, Aikawa M Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques. Circulation. 2004;110:1953-9 - PMID: 15451791 - DOI: 10.1161/01.CIR.0000143174.41810.10
Waller C, Hiller K, Kahler E, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer W Serial magnetic resonance imaging of microvascular remodeling in the infarcted rat heart. Circulation. 2001;103(11):1564-9 - PMID: 11257086 - DOI: 10.1161/01.cir.103.11.1564
Rabkin E, Aikawa M, Stone J, Fukumoto Y, Libby P, Schoen F Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation. 2001;104:2525-32 - PMID: 11714645 - DOI: 10.1161/hc4601.099489
Aikawa M, Rabkin E, Sugiyama S, Voglic S, Fukumoto Y, Furukawa Y, Shiomi M, Schoen F, Libby P An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation. 2001;103:276-83 - PMID: 11208689 - DOI: 10.1161/01.cir.103.2.276
Fukumoto Y, Libby P, Rabkin E, Hill C, Enomoto M, Hirouchi Y, Shiomi M, Aikawa M Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. Circulation. 2001;103:993-9 - PMID: 11181475 - DOI: 10.1161/01.cir.103.7.993
Aikawa M, Voglic S, Sugiyama S, Rabkin E, Taubman M, Fallon J, Libby P Dietary lipid lowering reduces tissue factor expression in rabbit atheroma. Circulation. 1999;100:1215-22 - PMID: 10484543 - DOI: 10.1161/01.cir.100.11.1215
Aikawa M, Rabkin E, Okada Y, Voglic S, Clinton S, Brinckerhoff C, Sukhova G, Libby P Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization. Circulation. 1998;97:2433-44 - PMID: 9641696 - DOI: 10.1161/01.cir.97.24.2433
Nakagawa T, Sukhova G, Rabkin E, Winters G, Schoen F, Libby P Acute rejection accelerates graft coronary disease in transplanted rabbit hearts. Circulation. 1995;92:987-93 - PMID: 7641383 - DOI: 10.1161/01.cir.92.4.987
Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis. Circulation. 2008;118(18):1802-9 - PMID: 18852366 - PMCID: PMC2729441 - DOI: 10.1161/CIRCULATIONAHA.108.785881
Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease. Circulation. 2009;119(13):1785-94 - PMID: 19307473 - PMCID: PMC2717745 - DOI: 10.1161/CIRCULATIONAHA.108.827972
Christen T*, Nahrendorf M*, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P Molecular Imaging of Innate Immune Cell Function in Transplant Rejection. Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889 - DOI: 10.1161/CIRCULATIONAHA.108.796888
Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Handschumacher MD, Sullivan S, Johnson B, Titus JS, Iwamoto Y, Wylie-Sears J, Levine RA, Carpentier A Active Adaptation of the Tethered Mitral Valve. Insights Into a Compensatory Mechanism for Functional Mitral Regurgitation. Circulation. 2009;120(4):334-42 - PMID: 19597052 - PMCID: PMC2752046 - DOI: 10.1161/CIRCULATIONAHA.108.846782
Ronald JA*, Chen JW*, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques. Circulation. 2009;120(7):592-9 - PMID: 19652086 - PMCID: PMC2736635 - DOI: 10.1161/CIRCULATIONAHA.108.813998
Nahrendorf M, Pittet MJ, Swirski FK Monocytes: protagonists of infarct inflammation and repair after myocardial infarction. Circulation. 2010;121(22):2437-45 - PMID: 20530020 - PMCID: PMC2892474 - DOI: 10.1161/CIRCULATIONAHA.109.916346
Cheng S*, Cohen KS*, Shaw SY*, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ Association of Colony-Forming Units With Coronary Artery and Abdominal Aortic Calcification. Circulation. 2010;122(12):1176-1182 - PMID: 20823386 - PMCID: PMC3050056 - DOI: 10.1161/CIRCULATIONAHA.109.931279
Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis. Circulation. 2010;122(17):1707-15 - PMID: 20937980 - PMCID: PMC3003265 - DOI: 10.1161/CIRCULATIONAHA.109.891804
Sakhuja R, Suh WM, Jaffer FA, Jang IK Residual Thrombogenic Substrate After Rupture of a Lipid-Rich Plaque: Possible Mechanism of Acute Stent Thrombosis? Circulation. 2010;122(22):2349-2350 - PMID: 21147731 - DOI: 10.1161/CIRCULATIONAHA.110.970079
Buxton DB, Antman M, Danthi N, Dilsizian V, Fayad ZA, Garcia MJ, Jaff MR, Klimas M, Libby P, Nahrendorf M, Sinusas AJ, Wickline SA, Wu JC, Bonow RO, Weissleder R Report of the national heart, lung, and blood institute working group on the translation of cardiovascular molecular imaging. Circulation. 2011;123(19):2157-63 - PMID: 21576680 - PMCID: PMC3119488 - DOI: 10.1161/CIRCULATIONAHA.110.000943
Shaw SY, Brettman AD Phenotyping patient-derived cells for translational studies in cardiovascular disease. Circulation. 2011;124(22):2444-55 - PMID: 22125190 - PMCID: PMC3263367 - DOI: 10.1161/CIRCULATIONAHA.111.043943
Robbins CS, Chudnovskiy A, Rauch PJ, Figueiredo JL, Iwamoto Y, Gorbatov R, Etzrodt M, Weber GF, Ueno T, van Rooijen N, Mulligan-Kehoe MJ, Libby P, Nahrendorf M, Pittet MJ, Weissleder R, Swirski FK Extramedullary Hematopoiesis Generates Ly-6Chigh Monocytes that Infiltrate Atherosclerotic Lesions. Circulation. 2011;125(2):364-74 - PMID: 22144566 - PMCID: PMC3263762 - DOI: 10.1161/CIRCULATIONAHA.111.061986
Moon H, Park HE, Kang J, Lee H, Cheong C, Lim YT, Ihm SH, Seung KB, Jaffer FA, Narula J, Chang K, Hong KS Noninvasive Assessment of Myocardial Inflammation by Cardiovascular Magnetic Resonance in a Rat Model of Experimental Autoimmune Myocarditis. Circulation. 2012;125(21):2603-12 - PMID: 22550157 - DOI: 10.1161/CIRCULATIONAHA.111.075283
Degousee N, Simpson J, Fazel S, Scholich K, Angoulvant D, Angioni C, Schmidt H, Korotkova M, Stefanski E, Wang XH, Lindsay TF, Ofek E, Pierre S, Butany J, Jakobsson PJ, Keating A, Li RK, Nahrendorf M, Geisslinger G, Backx PH, Rubin BB Lack of Microsomal Prostaglandin E2 Synthase-1 in Bone Marrow Derived Myeloid Cells Impairs Left Ventricular Function and Increases Mortality after Acute Myocardial Infarction. Circulation. 2012;125(23):2904-13 - PMID: 22589381 - DOI: 10.1161/CIRCULATIONAHA.112.099754
Majmudar MD, Keliher EJ, Heidt T, Leuschner F, Truelove J, Sena BF, Gorbatov R, Iwamoto Y, Dutta P, Wojtkiewicz G, Courties G, Sebas M, Borodovsky A, Fitzgerald K, Nolte MW, Dickneite G, Chen JW, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice. Circulation. 2013;127(20):2038-2046 - PMID: 23616627 - PMCID: PMC3661714 - DOI: 10.1161/CIRCULATIONAHA.112.000116
Kumar V, Patel N, Van Houzen N, Saini N Brugada-type electrocardiographic changes induced by Fever. Circulation. 2013;127(21):2145-6 - PMID: 23716383 - DOI: 10.1161/CIRCULATIONAHA.112.000901
Kroll MW, Lakkireddy DR, Stone JR, Luceri RM TASER Electronic Control Devices and Cardiac Arrests: Coincidental or Causal? Circulation. 2014;129(1):93-100 - PMID: 24396012 - DOI: 10.1161/CIRCULATIONAHA.113.004401
Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity. Circulation. 2014;129(16):1677-87 - PMID: 24488984 - PMCID: PMC3997655 - DOI: 10.1161/CIRCULATIONAHA.113.006381
Hara T, Truelove J, Tawakol A, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA FDG-PET/CT Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus. Circulation. 2014;130(13):1044-52 - PMID: 25070665 - PMCID: PMC4174982 - DOI: 10.1161/CIRCULATIONAHA.114.008902
Tawakol A, Hara T, Truelove J, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus" Circulation. 2015;131(24):e531-2 - PMID: 26078375 - DOI: 10.1161/CIRCULATIONAHA.115.014802
Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction. Circulation. 2015;132(20):1880-90 - PMID: 26358260 - PMCID: PMC4651795 - DOI: 10.1161/CIRCULATIONAHA.115.016160
Liong M, Shao H, Haun JB, Lee H, Weissleder R Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications. Adv Mater. 2010;22(45):5168-72 - PMID: 20859943 - PMCID: PMC2993874 - DOI: 10.1002/adma.201002219
Liong M, Tassa C, Shaw SY, Lee H, Weissleder R Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization. Adv Mater. 2011;23(36):H254-7 - PMID: 21780311 - PMCID: PMC3584698 - DOI: 10.1002/adma.201101401
Yoon TJ*, Lee H*, Shao H, Hilderbrand SA, Weissleder R Multicore Assemblies Potentiate Magnetic Properties of Biomagnetic Nanoparticles. Adv Mater. 2011;23(41):4793-7 - PMID: 21953810 - PMCID: PMC3224986 - DOI: 10.1002/adma.201102948
Im H, Bantz KC, Lee SH, Johnson TW, Haynes CL, Oh SH Self-assembled plasmonic nanoring cavity arrays for SERS and LSPR biosensing. Adv Mater. 2013;25(19):2678-85 - PMID: 23436239 - DOI: 10.1002/adma.201204283
De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nat Neurosci. 2014;17(9):1156-1163 - PMID: 25129075 - PMCID: PMC4292795 - DOI: 10.1038/nn.3786
Razansky D, Distel M, Vinegoni C, Ma R, Perrimon N, Koster RW, Ntziachristos V Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo Nat Photonics. 2009;3:412 - 417
Mahmood U Near infrared optical applications in molecular imaging. Earlier, more accurate assessment of disease presence, disease course, and efficacy of disease treatment. IEEE Eng Med Biol. 2004;23(4):58-66 - PMID: 15508386 - DOI: 10.1109/memb.2004.1337950
Gounari F, Chang R, Cowan J, Guo Z, Dose M, Gounaris E, Khazaie K. Loss of adenomatous polyposis coli gene function disrupts thymic development Nat Immunol. 2005;6(8):800-9 - PMID: 16025118 - PMCID: PMC4662936 - DOI: 10.1038/ni1228
Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006;7(3):284-92 - PMID: 16444258 - DOI: 10.1038/ni1306
Fu W, Wojtkiewicz G, Weissleder R, Benoist C, Mathis D Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nat Immunol. 2012;13(4):361-8 - PMID: 22366893 - PMCID: PMC3309063 - DOI: 10.1038/ni.2233
Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth Nat Immunol. 2015;17(2):159-168 - PMID: 26642357 - DOI: 10.1038/ni.3343
Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, Moon BS, Axtell RC, Ho PP, Steinberg GK, Lewis DB, Sobel RA, Han DK, Steinman L, Snyder MP, Hla T, Han MH Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nat Immunol. 2013;14(11):1166-72 - PMID: 24076635 - PMCID: PMC4014310 - DOI: 10.1038/ni.2730
Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Cote D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood. 2007;109:2708-17 - PMID: 17119115 - PMCID: PMC1852222 - DOI: 10.1182/blood-2006-07-035857
Leleu X, Jia X, Runnels J, Ngo HT, Moreau AS, Farag M, Spencer JA, Pitsillides CM, Hatjiharissi E, Roccaro A, O'Sullivan G, McMillin DW, Moreno D, Kiziltepe T, Carrasco R, Treon SP, Hideshima T, Anderson KC, Lin CP, Ghobrial IM The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia. Blood. 2007;110:4417-26 - PMID: 17761832 - PMCID: PMC2234792 - DOI: 10.1182/blood-2007-05-092098
Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood. 2008;111(10):5195-204 - PMID: 18326817 - PMCID: PMC2384142 - DOI: 10.1182/blood-2007-09-111567
Rufer N, Zippelius A, Batard P, Pittet M, Kurth I, Corthesy P, Cerottini J, Leyvraz S, Roosnek E, Nabholz M, Romero P Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood. 2003;102:1779-87 - PMID: 12750165 - DOI: 10.1182/blood-2003-02-0420
Kerre T, De Smet G, De Smedt M, Zippelius A, Pittet M, Langerak A, De Bosscher J, Offner F, Vandekerckhove B, Plum J Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells. Blood. 2002;99:1620-6 - PMID: 11861276 - DOI: 10.1182/blood.v99.5.1620
Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922 - DOI: 10.1182/blood-2009-01-198408
Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma. Blood. 2009;114(3):619-29 - PMID: 19443661 - PMCID: PMC2713475 - DOI: 10.1182/blood-2009-01-199281
Azab A, Runnels J, Pitsillides C, Moreau A, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson A, Alt C, Burwick N, Roccaro A, Ngo H, Farag M, Melhem M, Sacco A, Munshi N, Hideshima T, Rollins B, Anderson K, Kung A, Lin CP, Ghobrial I CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood. 2009;113:4341-51 - PMID: 19139079 - PMCID: PMC2676090 - DOI: 10.1182/blood-2008-10-186668
Kunstfeld R, Hirakawa S, Hong Y-K, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin CP, Fiebiger E, Wu Y, Hicklin D, Bohlen P, Detmar M VEGF-A overexpression leads to lymphatic vessel enlargement and persistent skin inflammation Blood. 2004;104:1048-57
Higgins JM, Sloan SR Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders. Blood. 2008;112(6):2546-53 - PMID: 18535200 - DOI: 10.1182/blood-2008-03-146415
Higgins JM, Sloan SR Response: Other factors may contribute to differences between sickle cell and non-sickle cell patients. Blood. 2010;115(21):4315-6 - PMID: 20508172
Meynard D, Vaja V, Sun CC, Corradini E, Chen S, Lopez-Otin C, Grgurevic L, Hong CC, Stirnberg M, Gutschow M, Vukicevic S, Babitt JL, Lin HY Regulation of TMPRSS6 by BMP6 and iron in human cells and mice. Blood. 2011;118(3):747-56 - PMID: 21622652 - PMCID: PMC3142910 - DOI: 10.1182/blood-2011-04-348698
Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, Willenbacher W, Eller K, Wolf D, Seifert M, Sun CC, Babitt JL, Hong CC, Menhall T, Gearing P, Lin HY, Weiss G Pharmacologic inhibition of hepcidin expression reverses anemia of chronic disease in rats. Blood. 2011;118(18):4977-84 - PMID: 21730356 - PMCID: PMC3208302 - DOI: 10.1182/blood-2011-03-345066
Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood. 2011;118(10):2849-56 - PMID: 21765021 - PMCID: PMC3172801 - DOI: 10.1182/blood-2011-03-345165
Sarkar D, Spencer JA, Phillips JA, Zhao W, Schafer S, Spelke DP, Mortensen LJ, Ruiz JP, Vemula PK, Sridharan R, Kumar S, Karnik R, Lin CP, Karp JM Engineered cell homing. Blood. 2011;118(25):e184-91 - PMID: 22034631 - PMCID: PMC3242725 - DOI: 10.1182/blood-2010-10-311464
Maiso P, Liu Y, Morgan B, Azab A, Ren P, Martin MB, Zhang Y, Liu Y, Sacco A, Ngo H, Azab F, Quang P, Rodig SJ, Lin CP, Roccaro A, Rommel C, Ghobrial IM Defining the role of TORC1 and TORC2 in multiple myeloma. Blood. 2011;118(26):6860-70 - PMID: 22045983 - PMCID: PMC3245208 - DOI: 10.1182/blood-2011-03-342394
Azab AK, Quang P, Azab F, Pitsillides C, Thompson B, Chonghaile T, Patton JT, Maiso P, Monrose V, Sacco A, Ngo HT, Flores LM, Lin CP, Magnani JL, Kung AL, Letai A, Carrasco R, Roccaro AM, Ghobrial IM P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment. Blood. 2011;119(6):1468-78 - PMID: 22096244 - PMCID: PMC3286211 - DOI: 10.1182/blood-2011-07-368050
Santo L, Hideshima T, Kung AL, Tseng JC, Tamang D, Yang M, Jarpe M, van Duzer JH, Mazitschek R, Ogier WC, Cirstea D, Rodig S, Eda H, Scullen T, Canavese M, Bradner J, Anderson KC, Jones SS, Raje N Preclinical activity, pharmacodynamic and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma. Blood. 2012;119(11):2579-89 - PMID: 22262760 - PMCID: PMC3337713 - DOI: 10.1182/blood-2011-10-387365
Mosley AJ, Meekings KN, McCarthy C, Shepherd D, Cerundolo V, Mazitschek R, Tanaka Y, Taylor GP, Bangham CR Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection. Blood. 2006;108(12):3801-7 - PMID: 16912225 - DOI: 10.1182/blood-2006-03-013235
Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, Thompson B, Maiso P, Sun JD, Hart CP, Roccaro AM, Sacco A, Ngo HT, Lin CP, Kung AL, Carrasco RD, Vanderkerken K, Ghobrial IM Hypoxia promotes dissemination of multiple myeloma through acquisition of endothelial to mesenchymal transition-like features. Blood. 2012;119(24):5782-94 - PMID: 22394600 - PMCID: PMC3382938 - DOI: 10.1182/blood-2011-09-380410
Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ Circulating CD34+ progenitor cell frequency is associated with clinical and genetic factors. Blood. 2013;121(8):e50-6 - PMID: 23287867 - PMCID: PMC3578962 - DOI: 10.1182/blood-2012-05-424846
Levy O, Zhao W, Mortensen LJ, Leblanc S, Tsang K, Fu M, Phillips JA, Sagar V, Anandakumaran P, Ngai J, Cui CH, Eimon P, Angel M, Lin CP, Yanik MF, Karp JM mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation. Blood. 2013;122(14):e23-e32 - PMID: 23980067 - PMCID: PMC3790516 - DOI: 10.1182/blood-2013-04-495119
Meynard D, Babitt JL, Lin HY The liver: conductor of systemic iron regulation. Blood. 2013;123(2):168-76 - PMID: 24200681 - PMCID: PMC3888285 - DOI: 10.1182/blood-2013-06-427757
Babitt JL, Lin HY BuMPing iron with modified heparins. Blood. 2014;123(10):1440-1 - PMID: 24627550 - PMCID: PMC3945857 - DOI: 10.1182/blood-2014-01-549519
Nicolaou F, Teodoridis JM, Park H, Georgakis A, Farokhzad OC, Böttinger EP, Da Silva N, Rousselot P, Chomienne C, Ferenczi K, Arnaout MA, Shelley CS CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD. Blood. 2003;101(10):4033-41 - PMID: 12576324 - DOI: 10.1182/blood-2002-01-0324
Da Silva N, Bharti A, Shelley CS hnRNP-K and Pur(alpha) act together to repress the transcriptional activity of the CD43 gene promoter. Blood. 2002;100(10):3536-44 - PMID: 12411317 - DOI: 10.1182/blood.V100.10.3536
Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Del Toro R, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning. Blood. 2014;124(19):2937-47 - PMID: 25202142 - PMCID: PMC4224192 - DOI: 10.1182/blood-2014-08-593426
Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression. Blood. 2015;126(16):1930-9 - PMID: 26320100 - PMCID: PMC4608240 - DOI: 10.1182/blood-2015-06-649087
Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis Cancer Cell. 2002;1:269-77 - PMID: 12086863 - DOI: 10.1016/s1535-6108(02)00046-6
Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Janne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell. 2006;9(6):485-95 - PMID: 16730237 - DOI: 10.1016/j.ccr.2006.04.022
Wurdinger T, Tannous BA, Saydam O, Skog J, Grau S, Soutschek J, Weissleder R, Breakefield XO, Krichevsky AM miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells. Cancer Cell. 2008;14(5):382-393 - PMID: 18977327 - PMCID: PMC2597164 - DOI: 10.1016/j.ccr.2008.10.005
Rheinbay E, Louis DN, Bernstein BE, Suvà ML A Tell-Tail Sign of Chromatin: Histone Mutations Drive Pediatric Glioblastoma. Cancer Cell. 2012;21(3):329-331 - PMID: 22439930 - DOI: 10.1016/j.ccr.2012.03.001
Abdel-Wahab O, Adli M, Lafave LM, Gao J, Hricik T, Shih AH, Pandey S, Patel JP, Chung YR, Koche R, Perna F, Zhao X, Taylor JE, Park CY, Carroll M, Melnick A, Nimer SD, Jaffe JD, Aifantis I, Bernstein BE, Levine RL ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression. Cancer Cell. 2012;22(2):180-93 - PMID: 22897849 - PMCID: PMC3422511 - DOI: 10.1016/j.ccr.2012.06.032
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling. Cancer Cell. 2013;24(1):45-58 - PMID: 23770013 - PMCID: PMC3746037 - DOI: 10.1016/j.ccr.2013.05.004
Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma. Cancer Cell. 2014;26(5):668-81 - PMID: 25453903 - PMCID: PMC4492343 - DOI: 10.1016/j.ccell.2014.10.004
Pfirschke C, Garris C, Pittet MJ Common TLR5 Mutations Control Cancer Progression. Cancer Cell. 2015;27(1):1-3 - PMID: 25584886 - DOI: 10.1016/j.ccell.2014.12.008
Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network. Cell Stem Cell. 2010;6(6):591-602 - PMID: 20569696 - PMCID: PMC2897075 - DOI: 10.1016/j.stem.2010.03.016
Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A Reprogramming factor expression initiates widespread targeted chromatin remodeling. Cell Stem Cell. 2011;8(1):96-105 - PMID: 21211784 - PMCID: PMC3220622 - DOI: 10.1016/j.stem.2010.12.001
Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration. Cell Stem Cell. 2012;10(3):259-72 - PMID: 22385654 - PMCID: PMC3652251 - DOI: 10.1016/j.stem.2012.02.003
Silberstein LE, Lin CP A new image of the hematopoietic stem cell vascular niche. Cell Stem Cell. 2013;13(5):514-6 - PMID: 24209758 - PMCID: PMC4148778 - DOI: 10.1016/j.stem.2013.10.012
Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells Cell Stem Cell. 2015;16 (5):477-487 - PMID: 25957903 - PMCID: PMC4426344 - DOI: 10.1016/j.stem.2015.04.008
Devaraj NK, Weissleder R Biomedical Applications of Tetrazine Cycloadditions. Accounts Chem Res. 2011;44(9):816-27 - PMID: 21627112 - PMCID: PMC3166440 - DOI: 10.1021/ar200037t
Tassa C, Shaw SY, Weissleder R Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy. Accounts Chem Res. 2011;44(10):842-52 - PMID: 21661727 - PMCID: PMC3182289 - DOI: 10.1021/ar200084x
Hurtado-Lorenzo A, Skinner M, El Annan J, Futai M, Sun-Wada GH, Bourgoin S, Casanova J, Wildeman A, Bechoua S, Ausiello DA, Brown D, Marshansky V V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat Cell Biol. 2006;8(2):124-36 - PMID: 16415858 - DOI: 10.1038/ncb1348
Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA Programming human pluripotent stem cells into white and brown adipocytes. Nat Cell Biol. 2012;14(2):209-19 - PMID: 22246346 - PMCID: PMC3385947 - DOI: 10.1038/ncb2411
Jaffer F, Libby P, Weissleder R. Molecular and Cellular Imaging of Atherosclerosis, Emerging Applications J Am Coll Cardiol. 2006;47:1328-1338 - PMID: 16580517 - DOI: 10.1016/j.jacc.2006.01.029
Nahrendorf M, Hu K, Hiller K, Galuppo P, Fraccarollo D, Schweizer G, Haase A, Ertl G, Bauer W, Bauersachs J Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study. J Am Coll Cardiol. 2002;40(9):1695-700 - PMID: 12427425 - DOI: 10.1016/s0735-1097(02)02375-6
Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schar M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using positive contrast magnetic resonance imaging. J Am Coll Cardiol. 2008;52:483-91 - PMID: 18672170 - PMCID: PMC2628468 - DOI: 10.1016/j.jacc.2008.03.063
Jaffer FA Assessing niacin as an atherosclerosis therapeutic agent valuable insights provided by high-resolution vascular magnetic resonance imaging. J Am Coll Cardiol. 2009;54(19):1795-6 - PMID: 19874993 - DOI: 10.1016/j.jacc.2009.07.026
Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J Am Coll Cardiol. 2010;55(15):1629-38 - PMID: 20378083 - PMCID: PMC2852892 - DOI: 10.1016/j.jacc.2009.08.089
Jaffer FA, Calfon MA, Rosenthal A, Mallas G, Razansky RN, Mauskapf A, Weissleder R, Libby P, Ntziachristos V Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury. J Am Coll Cardiol. 2011;57(25):2516-26 - PMID: 21679853 - PMCID: PMC3123768 - DOI: 10.1016/j.jacc.2011.02.036
Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, Dutta P, Iwamoto Y, Ueno T, Begieneman MPV, Niessen HWM, Piek JJ, Vinegoni C, Pittet MJ, Swirski FK, Tawakol A, Di Carli M, Weissleder R, Nahrendorf M PET/MRI of Inflammation in Myocardial Infarction J Am Coll Cardiol. 2012;59:153-163 - PMID: 22222080 - PMCID: PMC3257823 - DOI: 10.1016/j.jacc.2011.08.066
Swirski FK, Nahrendorf M Macrophage - stem cell crosstalk after myocardial infarction. J Am Coll Cardiol. 2013;62(20):1902-4 - PMID: 23973700 - DOI: 10.1016/j.jacc.2013.07.058
Courties G, Heidt T, Sebas M, Iwamoto Y, Jeon D, Truelove J, Tricot B, Wojtkiewicz G, Dutta P, Sager HB, Borodovsky A, Novobrantseva T, Klebanov B, Fitzgerald K, Anderson DG, Libby P, Swirski FK, Weissleder R, Nahrendorf M In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing. J Am Coll Cardiol. 2013;63(15):1556-66 - PMID: 24361318 - PMCID: PMC3992176 - DOI: 10.1016/j.jacc.2013.11.023
Taqueti VR, Nahrendorf M, Di Carli MF Translational molecular imaging: repurposing an old technique to track cell migration into human atheroma. J Am Coll Cardiol. 2014;64(10):1030-2 - PMID: 25190239 - DOI: 10.1016/j.jacc.2014.07.004
Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, Ntziachristos V, Piek JJ, Stroes ES, Schwaiger M, Mann DL, Fayad ZA Imaging Systemic Inflammatory Networks in Ischemic Heart Disease. J Am Coll Cardiol. 2015;65(15):1583-1591 - PMID: 25881940 - PMCID: PMC4401833 - DOI: 10.1016/j.jacc.2015.02.034
Atri M, Zhang Z, Marques H, Gorelick J, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Gold M, Utility of preoperative ferumoxtran-10 enhanced MRI to evaluate retroperitoneal lymph node metastasis in advanced cervical cancer: Results of ACRIN 6671/GOG 0233. J Clin Oncol. 2011;29(15_suppl):5035 - PMID: 28023716
Gold M, Zhang Z, Marques H, Gorelick J, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Atri M MRI prior to systematic lymphadenectomy in patients with locally advanced cervical cancer. J Clin Oncol. 2011;29(15_suppl):5042 - PMID: 28023697
Santo L, Hideshima T, Kung AL, Yang M, Tamang D, Jarpe M, van Duzer JH, Mazitschek R, Cirstea D, Patel K, Tseng J, Rodig S, Pozzi S, Bradner J, Anderson KC, Jones SS, Raje NS The effect of selective inhibition of HDAC6 with ACY1215 on bortezomib activity in multiple myeloma (MM). J Clin Oncol. 2011;29(15_suppl):e18569 - PMID: 28023028
D'Souza G, Gross ND, Pai SI, Haddad R, Anderson KS, Rajan S, Gerber J, Gillison ML, Posner MR Oral human papillomavirus (HPV) infection in HPV-positive patients with oropharyngeal cancer and their partners. J Clin Oncol. 2014;32(23):2408-15 - PMID: 24778397 - PMCID: PMC4263818 - DOI: 10.1200/JCO.2014.55.1341
Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A IKKb regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways. Nat Commun. 2011;2:318 - PMID: 21587235 - PMCID: PMC3113230 - DOI: 10.1038/ncomms1317
Shi P, Scott MA, Ghosh B, Wan D, Wissner-Gross Z, Mazitschek R, Haggarty SJ, Yanik MF Synapse microarray identification of small molecules that enhance synaptogenesis. Nat Commun. 2011;2:510 - PMID: 22027590 - PMCID: PMC3544154 - DOI: 10.1038/ncomms1518
Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivovarov M, Sbarbati A, Nahrendorf M, Weissleder R Real-time in vivo imaging of the beating mouse heart at microscopic resolution Nat Commun. 2012;3:1054 - PMID: 22968700 - PMCID: PMC3622400 - DOI: 10.1038/ncomms2060
Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo. Nat Commun. 2013;4:1504 - PMID: 23422672 - PMCID: PMC3579506 - DOI: 10.1038/ncomms2506
Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H*, Weissleder R* Magnetic barcode assay for genetic detection of pathogens Nat Commun. 2013;4:1752 - PMID: 23612293 - PMCID: PMC3635151 - DOI: 10.1038/ncomms2745
Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun. 2013;4:2189 - PMID: 23877263 - PMCID: PMC3740589 - DOI: 10.1038/ncomms3189
Ageta-Ishihara N, Miyata T, Ohshima C, Watanabe M, Sato Y, Hamamura Y, Higashiyama T, Mazitschek R, Bito H, Kinoshita M Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation. Nat Commun. 2013;4:2532 - PMID: 24113571 - PMCID: PMC3826633 - DOI: 10.1038/ncomms3532
Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation. Nat Commun. 2014;5:3065 - PMID: 24445279 - PMCID: PMC4001802 - DOI: 10.1038/ncomms4065
Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R In vivo imaging of specific drug-target binding at subcellular resolution. Nat Commun. 2014;5:3946 - PMID: 24867710 - PMCID: PMC4362617 - DOI: 10.1038/ncomms4946
Lee SK, Mortensen LJ, Lin CP, Tung CH An authentic imaging probe to track cell fate from beginning to end. Nat Commun. 2014;5:5216 - PMID: 25323442 - PMCID: PMC4852472 - DOI: 10.1038/ncomms6216
Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nat Commun. 2014;5:5662 - PMID: 25489927 - PMCID: PMC4261930 - DOI: 10.1038/ncomms6662
Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, Hochberg FH, Breakefield XO, Lee H*, Weissleder R* Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma Nat Commun. 2015;6:6999 - PMID: 25959588 - PMCID: PMC4430127 - DOI: 10.1038/ncomms7999
Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, Breakefield XO Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters. Nat Commun. 2015;6:7029 - PMID: 25967391 - PMCID: PMC4435621 - DOI: 10.1038/ncomms8029
Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nat Commun. 2015;6:8692 - PMID: 26503691 - PMCID: PMC4711745 - DOI: 10.1038/ncomms9692
Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy. Nat Commun. 2015;6:8803 - PMID: 26541940 - PMCID: PMC4638135 - DOI: 10.1038/ncomms9803
Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW ADAM8 as a drug target in pancreatic cancer. Nat Commun. 2015;6:6175 - PMID: 25629724 - PMCID: PMC5014123 - DOI: 10.1038/ncomms7175
Chen X, Park HR, Pelton M, Piao X, Lindquist NC, Im H, Kim YJ, Ahn JS, Ahn KJ, Park N, Kim DS, Oh SH Atomic layer lithography of wafer-scale nanogap arrays for extreme confinement of electromagnetic waves. Nat Commun. 2013;4:2361 - PMID: 23999053 - DOI: 10.1038/ncomms3361
Chapman S, Dobrovolskaia M, Farahani K, Goodwin A, Joshi A, Lee H, Meade T, Pomper M, Ptak K, Rao J, Singh R, Sridhar S, Stern S, Wang A, Weaver JB, Woloschak G, Yang L Nanoparticles for cancer imaging: The good, the bad, and the promise. Nano Today. 2013;8(5):454-460 - PMID: 25419228 - PMCID: PMC4240321 - DOI: 10.1016/j.nantod.2013.06.001
Haun JB*, Castro CM*, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R. Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples Sci Transl Med. 2011;3(71):71ra16 - PMID: 21346169 - PMCID: PMC3086073 - DOI: 10.1126/scitranslmed.3002048
Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA Indocyanine Green Enables Near-Infrared Fluorescence Imaging of Lipid-Rich, Inflamed Atherosclerotic Plaques Sci Transl Med. 2011;3 (84) ra45):84ra45 - PMID: 21613624 - PMCID: PMC3112179 - DOI: 10.1126/scitranslmed.3001577
Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Transl Med. 2011;3(104):104ra101 - PMID: 21998408 - PMCID: PMC3754876 - DOI: 10.1126/scitranslmed.3002191
Wood DK, Soriano A, Mahadevan L, Higgins JM, Bhatia SN A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease. Sci Transl Med. 2012;4(123):123ra26 - PMID: 22378926 - PMCID: PMC3633235 - DOI: 10.1126/scitranslmed.3002738
Issadore D, Chung J*, Shao H*, Liong M, Ghazani AA, Castro CM, Weissleder R*, Lee H* Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector Sci Transl Med. 2012;4 (141):141ra92 - PMID: 22764208 - PMCID: PMC3603277 - DOI: 10.1126/scitranslmed.3003747
Ullal AV*, Peterson V*, Agasti SS, Tuang S, Juric D, Castro CM, Weissleder R Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates Sci Transl Med. 2014;6(219):219ra9 - PMID: 24431113 - PMCID: PMC4063286 - DOI: 10.1126/scitranslmed.3007361
Kobzik L, Swirski FK MARCOing Monocytes for Elimination. Sci Transl Med. 2014;6(219):219fs4 - PMID: 24431109 - PMCID: PMC4374341 - DOI: 10.1126/scitranslmed.3008448
Mulder WJ, Jaffer FA, Fayad ZA, Nahrendorf M Imaging and Nanomedicine in Inflammatory Atherosclerosis. Sci Transl Med. 2014;6(239):239sr1 - PMID: 24898749 - PMCID: PMC4110972 - DOI: 10.1126/scitranslmed.3005101
Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin Sci Transl Med. 2014;6 (261):261ra152 - PMID: 25378644 - PMCID: PMC4330962 - DOI: 10.1126/scitranslmed.3009318
Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015;7(288):288ra77 - PMID: 25995223 - PMCID: PMC4675670 - DOI: 10.1126/scitranslmed.aaa3575
Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamal N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R Predicting therapeutic nano-medicine efficacy using a companion MR imaging nanoparticle. Sci Transl Med. 2015;7:314 - PMID: 26582898 - PMCID: PMC5462466 - DOI: 10.1126/scitranslmed.aac6522
Swirski FK, Nahrendorf M, Libby P The ins and outs of inflammatory cells in atheromata. Cell Metab. 2012;15(2):135-6 - PMID: 22326216 - DOI: 10.1016/j.cmet.2012.01.012
Dai N, Zhao L, Wrighting D, Krämer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins. Cell Metab. 2015;21(4):609-21 - PMID: 25863250 - PMCID: PMC4663978 - DOI: 10.1016/j.cmet.2015.03.006
Perez JM, Simeone FJ, Saeki Y, Josephson L, Weissleder R Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media J Am Chem Soc. 2003;125:10192-3 - PMID: 12926940 - DOI: 10.1021/ja036409g
Perez JM, O'Loughin T, Simeone F J, Weissleder R, Josephson L DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents J Am Chem Soc. 2002;124:2856-7 - PMID: 11902860 - DOI: 10.1021/ja017773n
E.C. Wiener, F.P. Auteri, J.W. Chen, M.W. Brechbiel, O.A. Gansow, D.J. Schneider, R.L. Belford, R.B. Clarkson, P.C. Lauterbur Molecular Dynamics of Ion-Chelate Complexes Attached to Starburst(TM) Dendrimers J Am Chem Soc. 1996;118:7774-7782
Hilderbrand S, Lim M, Lippard S Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. J Am Chem Soc. 2004;126:4972-8 - PMID: 15080703 - DOI: 10.1021/ja038471j
Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation. J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134 - DOI: 10.1021/ja903922u
Rodriguez E, Nilges M, Weissleder R, Chen JW Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity. J Am Chem Soc. 2010;132(1):168-77 - PMID: 19968300 - PMCID: PMC2802665 - DOI: 10.1021/ja905274f
Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots Using Tetrazine-Norbornene Cycloaddition. J Am Chem Soc. 2010;132(23):7838-9 - PMID: 20481508 - PMCID: PMC2892974 - DOI: 10.1021/ja101677r
Brueckner C, Gotz DC, Fox SP, Ryppa C, McCarthy JR, Bruhn T, Akhigbe J, Banerjee S, Daddario P, Daniell HW, Zeller M, Boyle R, Bringmann G Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins. J Am Chem Soc. 2011;133(22):8740-8752 - PMID: 21534626 - DOI: 10.1021/ja202451t
Stahl P, Kissau L, Mazitschek R, Huwe A, Furet P, Giannis A, Waldmann H Total synthesis and biological evaluation of the nakijiquinones. J Am Chem Soc. 2001;123(47):11586-93 - PMID: 11716712 - DOI: 10.1021/ja011413i
Niers JM*, Chen JW*, Lewandrowski G, Kerami M, Garanger E, Wojtkiewicz G, Waterman P, Keliher E, Weissleder R, Tannous BA Single Reporter for Targeted Multimodal in Vivo Imaging. J Am Chem Soc. 2012;134(11):5149-56 - PMID: 22397453 - PMCID: PMC3310895 - DOI: 10.1021/ja209868g
Agasti SS, Liong M, Peterson VM, Lee H, Weissleder R Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cell. J Am Chem Soc. 2012;134(45):18499-18502 - PMID: 23092113 - PMCID: PMC3498844 - DOI: 10.1021/ja307689w
Chen CH, Sarkar A, Song YA, Miller MA, Kim SJ, Griffith LG, Lauffenburger DA, Han J Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator. J Am Chem Soc. 2011;133(27):10368-71 - PMID: 21671557 - PMCID: PMC3165005 - DOI: 10.1021/ja2036628
Chen CH, Miller MA, Sarkar A, Beste MT, Isaacson KB, Lauffenburger DA, Griffith LG, Han J Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis. J Am Chem Soc. 2012;135(5):1645-8 - PMID: 23157326 - PMCID: PMC3566300 - DOI: 10.1021/ja307866z
Syeda R, Holden MA, Hwang WL, Bayley H Screening blockers against a potassium channel with a droplet interface bilayer array. J Am Chem Soc. 2008;130(46):15543-8 - PMID: 18950170 - DOI: 10.1021/ja804968g
Hwang WL, Chen M, Cronin B, Holden MA, Bayley H Asymmetric droplet interface bilayers. J Am Chem Soc. 2008;130(18):5878-9 - PMID: 18407631 - DOI: 10.1021/ja802089s
Hwang WL, Holden MA, White S, Bayley H Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling. J Am Chem Soc. 2007;129(38):11854-64 - PMID: 17764183 - DOI: 10.1021/ja074071a
Insin N, Tracy JB, Lee H, Zimmer JP, Westervelt RM, Bawendi MG Incorporation of iron oxide nanoparticles and quantum dots into silica microspheres. ACS Nano. 2008;2(2):197-202 - PMID: 19206619 - DOI: 10.1021/nn700344x
Fourches D, Pu D, Tassa C, Weissleder R, Shaw SY, Mumper RJ, Tropsha A Quantitative Nanostructure-Activity Relationship Modeling. ACS Nano. 2010;4(10):5703-12 - PMID: 20857979 - PMCID: PMC2997621 - DOI: 10.1021/nn1013484
Haun J, Devaraj NK, Marinelli B, Lee H, Weissleder R Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry. ACS Nano. 2011;5(4):3204-13 - PMID: 21351804 - PMCID: PMC3088084 - DOI: 10.1021/nn200333m
Chung H, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles. ACS Nano. 2011;5(11):8834-41 - PMID: 21967150 - PMCID: PMC3222727 - DOI: 10.1021/nn2029692
Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R Nanoparticle Mediated Measurement of Target-Drug Binding in Cancer Cells. ACS Nano. 2011;5(11):9216-24 - PMID: 21962084 - PMCID: PMC3297118 - DOI: 10.1021/nn203450p
Peterson VM, Castro CM, Lee H, Weissleder R Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing. ACS Nano. 2012;6(4):3506-13 - PMID: 22424443 - PMCID: PMC3337350 - DOI: 10.1021/nn300536y
Min C, Shao H, Liong M, Yoon TJ, Weissleder R, Lee H Mechanism of Magnetic Relaxation Switching Sensing. ACS Nano. 2012;6(8):6821-8 - PMID: 22762250 - PMCID: PMC3429660 - DOI: 10.1021/nn301615b
Rho J, Chung J, Im H, Liong M, Shao H, Castro CM, Weissleder R, Lee H Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles. ACS Nano. 2013;7(12):11227-33 - PMID: 24295203 - PMCID: PMC3898036 - DOI: 10.1021/nn405016y
Lai CP, Mardini O, Ericsson M, Prabhakar S, Maguire C, Chen JW, Tannous BA, Breakefield XO Dynamic Biodistribution of Extracellular Vesicles In Vivo Using a Multimodal Imaging Reporter. ACS Nano. 2014;8(1):483-94 - PMID: 24383518 - PMCID: PMC3934350 - DOI: 10.1021/nn404945r
Lee K, Shao H, Weissleder R, Lee H Acoustic Purification of Extracellular Microvesicles. ACS Nano. 2015;9(3):2321-7 - PMID: 25672598 - PMCID: PMC4373978 - DOI: 10.1021/nn506538f
Nair AV, Keliher EJ, Core AB, Brown D, Weissleder R Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo. ACS Nano. 2015;9(4):3641-53 - PMID: 25790730 - PMCID: PMC4414893 - DOI: 10.1021/acsnano.5b00428
Wittenberg NJ, Im H, Johnson TW, Xu X, Warrington AE, Rodriguez M, Oh SH Facile assembly of micro- and nanoarrays for sensing with natural cell membranes. ACS Nano. 2011;5(9):7555-64 - PMID: 21842844 - PMCID: PMC3183111 - DOI: 10.1021/nn202554t
Im H, Lee SH, Wittenberg NJ, Johnson TW, Lindquist NC, Nagpal P, Norris DJ, Oh SH Template-stripped smooth Ag nanohole arrays with silica shells for surface plasmon resonance biosensing. ACS Nano. 2011;5(8):6244-53 - PMID: 21770414 - PMCID: PMC3160512 - DOI: 10.1021/nn202013v
Im H, Lindquist NC, Lesuffleur A, Oh SH Atomic layer deposition of dielectric overlayers for enhancing the optical properties and chemical stability of plasmonic nanoholes. ACS Nano. 2010;4(2):947-54 - PMID: 20131870 - DOI: 10.1021/nn901842r
Jaffer FA, Weissleder R Seeing within: molecular imaging of the cardiovascular system Circ Res. 2004;94(4):433-45 - PMID: 15001542 - DOI: 10.1161/01.RES.0000119321.18573.5A
Kelly KA, Allport JR, Tsourkas A, Shinde-Patil VR, Josephson L, Weissleder R. Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle Circ Res. 2005;96(3):327-36 - PMID: 15653572 - DOI: 10.1161/01.RES.0000155722.17881.dd
Nahrendorf M, Sosnovik D, Waterman P, Swirski F, Pande A, Aikawa E, Figueiredo JL, Pittet M, Weissleder R. Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct Circ Res. 2007;100:1218-1225 - PMID: 17379832 - DOI: 10.1161/01.RES.0000265064.46075.31
Paruchuri S, Yang J, Aikawa E, Melero-Martin J, Khan Z, Loukogeorgakis S, Schoen F, Bischoff J Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-{beta}2. Circ Res. 2006;99(8):861-9 - PMID: 16973908 - PMCID: PMC2810464 - DOI: 10.1161/01.RES.0000245188.41002.2c
Aikawa M, Rabkin E, Voglic S, Shing H, Nagai R, Schoen F, Libby P Lipid lowering promotes accumulation of mature smooth muscle cells expressing smooth muscle myosin heavy chain isoforms in rabbit atheroma. Circ Res. 1998;83:1015-26 - PMID: 9815149 - DOI: 10.1161/01.res.83.10.1015
Leuschner F, Panizzi P, Chico-Calero I, Lee WW, Ueno T, Cortez-Retamozo V, Waterman P, Gorbatov R, Marinelli B, Iwamoto Y, Chudnovskiy A, Figueiredo JL, Sosnovik DE, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction. Circ Res. 2010;107(11):1364-73 - PMID: 20930148 - PMCID: PMC2992104 - DOI: 10.1161/CIRCRESAHA.110.227454
Leuschner F, Nahrendorf M Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic. Circ Res. 2011;108(5):593-606 - PMID: 21372291 - PMCID: PMC3397211 - DOI: 10.1161/CIRCRESAHA.110.232678
Nahrendorf M, McCarthy JR, Libby P Over a hump for imaging atherosclerosis: nanobodies visualize vascular cell adhesion molecule-1 in inflamed plaque. Circ Res. 2012;110(7):902-3 - PMID: 22461358 - DOI: 10.1161/CIRCRESAHA.112.267260
Courties G, Nahrendorf M Enlightened stem cells in the heart: more efficient and safer reporter gene imaging. Circ Res. 2012;111(12):1486-7 - PMID: 23223928 - DOI: 10.1161/CIRCRESAHA.112.280982
Majmudar MD, Yoo J, Keliher E, Truelove JJ, Iwamoto Y, Sena B, Dutta P, Borodovsky A, Fitzgerald K, Di Carli MF, Libby P, Anderson D, Swirski FK, Weissleder R, Nahrendorf M Polymeric Nanoparticle PET/MR Imaging Allows Macrophage Detection in Atherosclerotic Plaques. Circ Res. 2013;112(5):755-61 - PMID: 23300273 - PMCID: PMC3586287 - DOI: 10.1161/CIRCRESAHA.111.300576
Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH Endoscopic Time-Lapse Imaging of Immune Cells in Infarcted Mouse Hearts. Circ Res. 2013;112(6):891-899 - PMID: 23392842 - PMCID: PMC3834270 - DOI: 10.1161/CIRCRESAHA.111.300484
Swirski FK, Robbins CS Neutrophils usher monocytes into sites of inflammation. Circ Res. 2013;112(5):744-5 - PMID: 23449542 - DOI: 10.1161/CIRCRESAHA.113.300867
Nahrendorf M, Swirski FK Monocyte and macrophage heterogeneity in the heart. Circ Res. 2013;112(12):1624-33 - PMID: 23743228 - PMCID: PMC3753681 - DOI: 10.1161/CIRCRESAHA.113.300890
Nahrendorf M, Swirski FK Fluorescent leukocytes enter plaque on the microscope stage. Circ Res. 2014;114(5):740-1 - PMID: 24577957 - PMCID: PMC3957183 - DOI: 10.1161/CIRCRESAHA.114.303520
Hilgendorf I, Gerhardt L, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherrer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium. Circ Res. 2014;114(10):1611-22 - PMID: 24625784 - PMCID: PMC4017349 - DOI: 10.1161/CIRCRESAHA.114.303204
Heidt T, Courties G, Dutta P, Sager H, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction. Circ Res. 2014;115(2):284-95 - PMID: 24786973 - PMCID: PMC4082439 - DOI: 10.1161/CIRCRESAHA.115.303567
Nahrendorf M, Swirski FK Regulating repair: regulatory T cells in myocardial infarction. Circ Res. 2014;115(1):7-9 - PMID: 24951758 - PMCID: PMC4094354 - DOI: 10.1161/CIRCRESAHA.114.304295
Swirski FK, Nahrendorf M Do vascular smooth muscle cells differentiate to macrophages in atherosclerotic lesions? Circ Res. 2014;115(7):605-6 - PMID: 25214571 - PMCID: PMC4166538 - DOI: 10.1161/CIRCRESAHA.114.304925
Courties G, Herisson F, Sager H, Heidt T, Ye Y, Ying W, Sun Y, Severe N, Dutta P, Scharff J, Scadden D, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells. Circ Res. 2015;116(3):407-17 - PMID: 25362208 - PMCID: PMC4312511 - DOI: 10.1161/CIRCRESAHA.116.305207
Nahrendorf M, Swirski FK Lifestyle Effects on Hematopoiesis and Atherosclerosis. Circ Res. 2015;116(5):884-894 - PMID: 25722442 - PMCID: PMC4347940 - DOI: 10.1161/CIRCRESAHA.116.303550
Konishi M, Erdem SS, Weissleder R, Lichtman AH, McCarthy J, Libby P Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis. Circ Res. 2015;117(6):502-12 - PMID: 26199323 - PMCID: PMC4553143 - DOI: 10.1161/CIRCRESAHA.115.306364
Ye YX, Calcagno C, Binderup T, Courties G, Keliher E, Wojtkiewicz GR, Iwamoto Y, Tang J, Perez-Medina C, Mani V, Ishino S, Johnbeck CB, Knigge U, Fayad ZA, Libby P, Weissleder R, Tawakol A, Dubey S, Belanger AP, Di Carli MF, Swirski FK, Kjær A, Mulder W, Nahrendorf M Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis. Circ Res. 2015;117(10):835-45 - PMID: 26394773 - PMCID: PMC4619168 - DOI: 10.1161/CIRCRESAHA.115.307024
Taboada E, Solanas R, Rodriguez E, Weissleder R, Roig A Supercritical-Fluid-Assisted One-Pot Synthesis of Biocompatible Core (γ-Fe2O3)/Shell(SiO2) Nanoparticles as High Relaxivity T2-Contrast Agents for Magnetic Resonance Imaging Adv Funct Mater. 2009;19 :2319-2324
Lee S, Johnson TW, Lindquist NC, Im H, Norris DJ, Oh SH Linewidth-Optimized Extraordinary Optical Transmission in Water with Template-Stripped Metallic Nanohole Arrays Adv Funct Mater. 2012;22(21):4439-4446
Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheumatol. 2009;60:2314-2324 - PMID: 19644878 - PMCID: PMC3080016 - DOI: 10.1002/art.24704
Stone JH, Khosroshahi A, Hilgenberg A, Spooner A, Isselbacher EM, Stone JR IgG4-related systemic disease and lymphoplasmacytic aortitis. Arthritis Rheumatol. 2009;60(10):3139-3145 - PMID: 19790067 - DOI: 10.1002/art.24798
Wang H, Smith RN, Spooner AE, Isselbacher EM, Cambria RP, Macgillivray TE, Stone JH, Stone JR Giant cell aortitis of the ascending aorta without signs or symptoms of systemic vasculitis is associated with elevated risk of distal aortic events. Arthritis Rheumatol. 2012;64(1):317-9 - PMID: 21953530 - DOI: 10.1002/art.33343
Stone JH, Khosroshahi A, Deshpande V, Chan JK, Heathcote JG, Aalberse R, Azumi A, Bloch DB, Brugge WR, Carruthers MN, Cheuk W, Cornell L, Castillo CF, Ferry JA, Forcione D, Klöppel G, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Masaki Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani D, Sato Y, Smyrk T, Stone JR, Takahira M, Umehara H, Webster G, Yamamoto M, Yi E, Yoshino T, Zamboni G, Zen Y, Chari S IgG4-Related disease: recommendations for the nomenclature of this condition and its individual organ system manifestations. Arthritis Rheumatol. 2012;64(10):3061-7 - PMID: 22736240 - PMCID: PMC5963880 - DOI: 10.1002/art.34593
Zhao M, Josephson L, Tang Y, Weissleder R Magnetic sensors for protease assays Angew Chem Int Ed Engl. 2003;42:1375-8 - PMID: 12671972 - DOI: 10.1002/anie.200390352
Pham W, Weissleder R, Tung CH An azulene dimer as a near-infrared quencher Angew Chem Int Ed Engl. 2002;41:3659-62, 3519 - PMID: 12370922 - DOI: 10.1002/1521-3773(20021004)41:19<3659::AID-ANIE3659>3.0.CO;2-Q
Tsourkas A, Hofstetter O, Hofstetter H, Weissleder R, Josephson L Magnetic Relaxation Switch Immunosensors Detect Enantiomeric Impurities Angew Chem Int Ed Engl. 2004;43(18):2395-2399 - PMID: 15114571 - DOI: 10.1002/anie.200352998
Koh I, Hong R, Weissleder R, Josephson L Sensitive NMR Sensors Detect Antibodies to Influenza. Angew Chem Int Ed Engl. 2008;47(22):4119-4121 - PMID: 18428168 - PMCID: PMC2668198 - DOI: 10.1002/anie.200800069
Lee H*, Yoon TJ*, Weissleder R Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System. Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069 - DOI: 10.1002/anie.200901791
Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition. Angew Chem Int Ed Engl. 2009;48(38):7013-6 - PMID: 19697389 - PMCID: PMC2790075 - DOI: 10.1002/anie.200903233
Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells. Angew Chem Int Ed Engl. 2010;19 (49):2869-2872 - PMID: 20306505 - PMCID: PMC3433403 - DOI: 10.1002/anie.200906120
Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R Synthesis and In Vivo Imaging of a (18) F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method. Angew Chem Int Ed Engl. 2011;50(8):1922-5 - PMID: 21328671 - PMCID: PMC3471140 - DOI: 10.1002/anie.201006579
Yoon TJ*, Lee H*, Shao H, Weissleder R Highly magnetic core-shell nanoparticles with a unique magnetization mechanism. Angew Chem Int Ed Engl. 2011;50(20):4663-6 - PMID: 21495138 - PMCID: PMC3334859 - DOI: 10.1002/anie.201100101
Budin G, Yang KS, Reiner T, Weissleder R Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification. Angew Chem Int Ed Engl. 2011;50(40):9378-81 - PMID: 21948435 - PMCID: PMC3187564 - DOI: 10.1002/anie.201103273
Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers. Angew Chem Int Ed Engl. 2011;51(2):450-4 - PMID: 22113923 - PMCID: PMC3309171 - DOI: 10.1002/anie.201105670
Karver MR, Weissleder R, Hilderbrand SA Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging. Angew Chem Int Ed Engl. 2011;51(4):920-2 - PMID: 22162316 - PMCID: PMC3304098 - DOI: 10.1002/anie.201104389
Rosenbaum C, Baumhof P, Mazitschek R, Müller O, Giannis A, Waldmann H Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors. Angew Chem Int Ed Engl. 2004;43(2):224-8 - PMID: 14695616 - DOI: 10.1002/anie.200352582
Huwe A, Mazitschek R, Giannis A Small molecules as inhibitors of cyclin-dependent kinases. Angew Chem Int Ed Engl. 2003;42(19):2122-38 - PMID: 12761741 - DOI: 10.1002/anie.200200540
Stahl P, Kissau L, Mazitschek R, Giannis A, Waldmann H Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors. Angew Chem Int Ed Engl. 2002;41(7):1174-8 - PMID: 12491250 - DOI: 10.1002/1521-3773(20020402)41:7<1174::aid-anie1174>3.0.co;2-v
Stieber F, Mazitschek R, Soric N, Giannis A, Waldmann H Traceless solid-phase synthesis of 2-aminothiazoles: receptor tyrosine kinase inhibitors with dual selectivity for Tie-2 and VEGFR-2. Angew Chem Int Ed Engl. 2002;41(24):4757-61 - PMID: 12481350 - DOI: 10.1002/anie.200290040
Mazitschek R, Mülbaier M, Giannis A IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids. Angew Chem Int Ed Engl. 2002;41(21):4059-61 - PMID: 12412081 - DOI: 10.1002/1521-3773(20021104)41:21<4059::AID-ANIE4059>3.0.CO;2-R
Baumhof P, Mazitschek R, Giannis A A Mild and Effective Method for the Transesterification of Carboxylic Acid Esters P.B. and R.M. are grateful to the Land Baden-Württemberg for a scholarship from the Landesgraduiertenförderung. Angew Chem Int Ed Engl. 2001;40(19):3672-3674 - PMID: 11592218 - DOI: 10.1002/1521-3773(20011001)40:19<3672::aid-anie3672>3.0.co;2-y
Wernert N, Stanjek A, Kiriakidis S, Hügel A, Jha HC, Mazitschek R, Giannis A Inhibition of Angiogenesis In Vivo by ets-1 Antisense Oligonucleotides-Inhibition of Ets-1 Transcription Factor Expression by the Antibiotic Fumagillin. Angew Chem Int Ed Engl. 1999;38(21):3228-3231 - PMID: 10556911 - DOI: 10.1002/(sici)1521-3773(19991102)38:21<3228::aid-anie3228>3.0.co;2-8
Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R Synthesis of [(18) F]BODIPY: Bifunctional Reporter for Hybrid Optical/Positron Emission Tomography Imaging. Angew Chem Int Ed Engl. 2012;51(19):4603-6 - PMID: 22473535 - PMCID: PMC3343182 - DOI: 10.1002/anie.201107957
Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R Bioorthogonal Imaging of Aurora Kinase A in Live Cells. Angew Chem Int Ed Engl. 2012;51(27):6598-603 - PMID: 22644700 - PMCID: PMC3523717 - DOI: 10.1002/anie.201200994
Budin G*, Chung HJ*, Lee H, Weissleder R A Magnetic Gram Stain for Bacterial Detection. Angew Chem Int Ed Engl. 2012;51(31):7752-5 - PMID: 22744868 - PMCID: PMC3496380 - DOI: 10.1002/anie.201202982
Carlson JC, Meimetis LG, Hilderbrand SA, Weissleder R BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes. Angew Chem Int Ed Engl. 2013;52(27):6917-6920 - PMID: 23712730 - PMCID: PMC3875324 - DOI: 10.1002/anie.201301100
Yang* KS, Budin* G, Tassa C, Kister O, Weissleder R Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells Angew Chem Int Ed Engl. 2013;52(40):10593-7 - PMID: 23960025 - PMCID: PMC3856564 - DOI: 10.1002/anie.201304096
Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging. Angew Chem Int Ed Engl. 2014;53(29):7531-4 - PMID: 24915832 - PMCID: PMC4122131 - DOI: 10.1002/anie.201403890
Josephson L, Perez JM, Weissleder R Magnetic Nanosensors for the Detection of Oligonucleotide Sequences. Angew Chem Int Ed Engl. 2001;40(17):3204-3206 - PMID: 29712059 - DOI: 10.1002/1521-3773(20010903)40:17<3204::AID-ANIE3204>3.0.CO;2-H
Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis. Mol Cell. 2009;36(4):682-95 - PMID: 19941827 - PMCID: PMC2800995 - DOI: 10.1016/j.molcel.2009.11.002
Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, Robinson J, Minie B, Chevrier N, Itzhaki Z, Blecher-Gonen R, Bornstein C, Amann-Zalcenstein D, Weiner A, Friedrich D, Meldrim J, Ram O, Cheng C, Gnirke A, Fisher S, Friedman N, Wong B, Bernstein BE, Nusbaum C, Hacohen N, Regev A, Amit I A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals. Mol Cell. 2012;47(5):810-22 - PMID: 22940246 - PMCID: PMC3873101 - DOI: 10.1016/j.molcel.2012.07.030
van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Mol Cell. 2015;61(1):170-80 - PMID: 26687680 - PMCID: PMC4707994 - DOI: 10.1016/j.molcel.2015.11.003
Harisinghani MG, Weissleder R Sensitive, noninvasive detection of lymph node metastases. PLoS Med. 2004;1(3):e66 - PMID: 15630471 - PMCID: PMC539052 - DOI: 10.1371/journal.pmed.0010066
Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma. PLoS Med. 2008;5(4):e85 - PMID: 18416599 - PMCID: PMC2292750 - DOI: 10.1371/journal.pmed.0050085
Condeelis J, Weissleder R In Vivo Imaging in Cancer. Cold Spring Harb Perspect Biol. 2010;2(12):a003848 - PMID: 20861158 - PMCID: PMC2982169 - DOI: 10.1101/cshperspect.a003848
Rashidian M, Keliher E, Dougan M, Juras PK, Cavallari M, Wojtkiewicz GR, Jacobsen J, Edens JG, Tas JM, Victora G, Weissleder R, Ploegh H The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer. ACS Cent Sci. 2015;1(3):142-147 - PMID: 26955657 - PMCID: PMC4778250 - DOI: 10.1021/acscentsci.5b00121
Ozsolak F, Goren A, Gymrek MA, Guttman M, Regev A, Bernstein BE, Milos PM Digital transcriptome profiling from attomole-level RNA samples. Genome Res. 2010;20(4):519-25 - PMID: 20133332 - PMCID: PMC2847755 - DOI: 10.1101/gr.102129.109
Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, Desalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res. 2012;22(9):1813-31 - PMID: 22955991 - PMCID: PMC3431496 - DOI: 10.1101/gr.136184.111
Attanasio C, Nord AS, Zhu Y, Blow MJ, Biddie SC, Mendenhall EM, Dixon J, Wright CA, Hosseini R, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Afzal V, Ren B, Bernstein B, Rubin E, Visel A, Pennacchio L Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis. Genome Res. 2014;24(6):920-9 - PMID: 24752179 - PMCID: PMC4032856 - DOI: 10.1101/gr.168930.113
Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006;203(1):141-152 - PMID: 16390934 - PMCID: PMC2118091 - DOI: 10.1084/jem.20050390
Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D. Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk J Exp Med. 2007;204:1911-1922 - PMID: 17646407 - PMCID: PMC2118664 - DOI: 10.1084/jem.20070285
Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204(12):3037-47 - PMID: 18025128 - PMCID: PMC2118517 - DOI: 10.1084/jem.20070885
Zippelius A, Pittet M, Batard P, Rufer N, de Smedt M, Guillaume P, Ellefsen K, Valmori D, Lienard D, Plum J, MacDonald H, Speiser D, Cerottini J, Romero P Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med. 2002;195:485-94 - PMID: 11854361 - PMCID: PMC2193620 - DOI: 10.1084/jem.20011658
Dutoit V, Rubio-Godoy V, Pittet M, Zippelius A, Dietrich P, Legal F, Guillaume P, Romero P, Cerottini J, Houghten R, Pinilla C, Valmori D Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans. J Exp Med. 2002;196:207-16 - PMID: 12119345 - PMCID: PMC2193921 - DOI: 10.1084/jem.20020242
Romero P, Dunbar P, Valmori D, Pittet M, Ogg G, Rimoldi D, Chen J, Lienard D, Cerottini J, Cerundolo V Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes. J Exp Med. 1998;188:1641-50 - PMID: 9802976 - PMCID: PMC2212507 - DOI: 10.1084/jem.188.9.1641
Speiser D, Pittet M, Valmori D, Dunbar R, Rimoldi D, Lienard D, MacDonald H, Cerottini J, Cerundolo V, Romero P In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes. J Exp Med. 1999;190:775-82 - PMID: 10499916 - PMCID: PMC2195637 - DOI: 10.1084/jem.190.6.775
Pittet M, Valmori D, Dunbar P, Speiser D, Lienard D, Lejeune F, Fleischhauer K, Cerundolo V, Cerottini J, Romero P High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. J Exp Med. 1999;190:705-15 - PMID: 10477554 - PMCID: PMC2195613 - DOI: 10.1084/jem.190.5.705
Chakraverty R, Cote D, Buchli J, Cotter P, Hsu R, Zhao G, Sachs T, Pitsillides C, Bronson R, Means T, Lin CP, Sykes M An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med. 2006;203:2021-31 - PMID: 16880259 - PMCID: PMC2118376 - DOI: 10.1084/jem.20060376
Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, Lee WW, Dutta P, Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J Exp Med. 2012;209(1):123-37 - PMID: 22213805 - PMCID: PMC3260875 - DOI: 10.1084/jem.20111009
Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, Pandey S, Shin JY, Telis L, Liu J, Bhatt PK, Monette S, Zhao X, Mason CE, Park CY, Bernstein BE, Aifantis I, Levine RL Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo. J Exp Med. 2013;210(12):2641-59 - PMID: 24218140 - PMCID: PMC3832937 - DOI: 10.1084/jem.20131141
Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014;211(6):1243-56 - PMID: 24821911 - PMCID: PMC4042649 - DOI: 10.1084/jem.20131471
Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M Macrophages retain hematopoietic stem cells in the spleen via VCAM-1. J Exp Med. 2015;212(4):497-512 - PMID: 25800955 - PMCID: PMC4387283 - DOI: 10.1084/jem.20141642
Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, Shalabi A, Shin T, Pardoll DM, Tsuchiya H B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med. 2001;193(7):839-46 - PMID: 11283156 - PMCID: PMC2193370 - DOI: 10.1084/jem.193.7.839
Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, Raine CS, Sobel RA, Han DK, Weissman I, Steinman L Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. J Exp Med. 2012;209(7):1325-34 - PMID: 22734047 - PMCID: PMC3405500 - DOI: 10.1084/jem.20101974
Shaw SY Molecular imaging in cardiovascular disease: targets and opportunities. Nat Rev Cardiol. 2009;6(9):569-79 - PMID: 19621013 - DOI: 10.1038/nrcardio.2009.119
Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation. Sci Adv. 2015;1(3):ePub - PMID: 26295063 - PMCID: PMC4539616 - DOI: 10.1126/sciadv.1400223
Osborn EA, Jaffer FA The year in molecular imaging. JACC Cardiovasc Imaging. 2010;3(11):1181-95 - PMID: 21071007 - PMCID: PMC3057415 - DOI: 10.1016/j.jcmg.2010.09.009
Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence. JACC Cardiovasc Imaging. 2012;5(6):607-15 - PMID: 22698530 - PMCID: PMC3376390 - DOI: 10.1016/j.jcmg.2012.01.017
Chen JW, Figueiredo JL, Wojtkiewicz GR, Siegel C, Iwamoto Y, Kim DE, Nolte MW, Dickneite G, Weissleder R, Nahrendorf M Selective Factor XIIa Inhibition Attenuates Silent Brain Ischemia: Application of Molecular Imaging Targeting Coagulation Pathway. JACC Cardiovasc Imaging. 2012;5(11):1127-38 - PMID: 23153913 - PMCID: PMC3502014 - DOI: 10.1016/j.jcmg.2012.01.025
Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans. JACC Cardiovasc Imaging. 2015;8(2):121-30 - PMID: 25577441 - PMCID: PMC6855915 - DOI: 10.1016/j.jcmg.2014.10.009
Nahrendorf M, Swirski FK PET Imaging of Leukocytes in Patients With Acute Myocardial Infarction. JACC Cardiovasc Imaging. 2015;8(12):1427-9 - PMID: 26699111 - DOI: 10.1016/j.jcmg.2015.10.004
Pai SI, Westra WH Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment. Annu Rev Pathol. 2009;4:49-70 - PMID: 18729723 - PMCID: PMC3703474 - DOI: 10.1146/annurev.pathol.4.110807.092158
Tung CH, Weissleder R Arginine containing peptides as delivery vectors Adv Drug Deliv Rev. 2003;55:281-94 - PMID: 12564981 - DOI: 10.1016/s0169-409x(02)00183-7
Bogdanov AA, Lewin M, Weissleder R Approaches and agents for imaging the vascular system Adv Drug Deliv Rev. 1999;37:279-293 - PMID: 10837740 - DOI: 10.1016/s0169-409x(98)00098-2
McCarthy JR, Weissleder R Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev. 2008;60:1241-1251 - PMID: 18508157 - PMCID: PMC2583936 - DOI: 10.1016/j.addr.2008.03.014
McCarthy JR Multifunctional agents for concurrent imaging and therapy in cardiovascular disease. Adv Drug Deliv Rev. 2010;62(11):1023-30 - PMID: 20654664 - PMCID: PMC2974776 - DOI: 10.1016/j.addr.2010.07.004
Weissleder R, Bogdanov A, Neuwelt EA, Papisov M Long-circulating iron oxides for MR imaging Adv Drug Deliv Rev. 1995;16:321-334
Bogdanov A, Weissleder R, Brady T Long-circulating blood pool imaging agents Adv Drug Deliv Rev. 1995;15:335-348
Shah K Mesenchymal stem cells engineered for cancer therapy. Adv Drug Deliv Rev. 2011;64(8):739-48 - PMID: 21740940 - PMCID: PMC3395998 - DOI: 10.1016/j.addr.2011.06.010
Vilardaga JP Switching modes for G protein-coupled receptor activation. Nat Chem Biol. 2006;2(8):395-6 - PMID: 16850011 - DOI: 10.1038/nchembio0806-395
Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, Hoyng SA, Lin HY, Bloch KD, Peterson RT Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2007;4(1):33-41 - PMID: 18026094 - PMCID: PMC2727650 - DOI: 10.1038/nchembio.2007.54
Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ Conformational cross-talk between alpha(2A)-adrenergic and mu-opioid receptors controls cell signaling. Nat Chem Biol. 2008;4:126-131 - PMID: 18193048 - DOI: 10.1038/nchembio.64
Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. Nat Chem Biol. 2009;5(10):734-42 - PMID: 19701185 - PMCID: PMC3032084 - DOI: 10.1038/nchembio.206
Bradner JE, West N, Grachan ML, Greenberg EF, Haggarty SJ, Warnow T, Mazitschek R Chemical phylogenetics of histone deacetylases. Nat Chem Biol. 2010;6(3):238-243 - PMID: 20139990 - PMCID: PMC2822059 - DOI: 10.1038/nchembio.313
Keller TL, Zocco D, Sundrud MS, Hendrick M, Edenius M, Yum J, Kim YJ, Lee HK, Cortese JF, Wirth DF, Dignam JD, Rao A, Yeo CY, Mazitschek R, Whitman M Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase Nat Chem Biol. 2012;8(3):311-7 - PMID: 22327401 - PMCID: PMC3281520 - DOI: 10.1038/nchembio.790
Isono K, Endo TA, Ku M, Yamada D, Suzuki R, Sharif J, Ishikura T, Toyoda T, Bernstein BE, Koseki H SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing. Dev Cell. 2013;26(6):565-577 - PMID: 24091011 - DOI: 10.1016/j.devcel.2013.08.016
Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R Imaging inflammation of the pancreatic islets in type 1 diabetes. Proc Natl Acad Sci U S A. 2004;101(34):12634-9 - PMID: 15304647 - PMCID: PMC515109 - DOI: 10.1073/pnas.0404307101
Ntziachristos V, Schellenberger EA, Ripoll J, Yessayan D, Graves E, Bogdanov A Jr, Josephson L, Weissleder R Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc Natl Acad Sci U S A. 2004;101(33):12294-9 - PMID: 15304657 - PMCID: PMC514472 - DOI: 10.1073/pnas.0401137101
Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K. Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-{beta} signals in vivo Proc Natl Acad Sci U S A. 2005;102(2):419-24 - PMID: 15623559 - PMCID: PMC544311 - DOI: 10.1073/pnas.0408197102
Grimm J, Kirsch DG, Windsor SD, Kim CF, Santiago PM, Ntziachristos V, Jacks T, Weissleder R. Use of gene expression profiling to direct in vivo molecular imaging of lung cancer Proc Natl Acad Sci U S A. 2005;102(40):14404-14409 - PMID: 16183744 - PMCID: PMC1242291 - DOI: 10.1073/pnas.0503920102
Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V. Volumetric tomography of fluorescent proteins through small animals in vivo Proc Natl Acad Sci U S A. 2005;102:18252-18257 - PMID: 16344470 - PMCID: PMC1317905 - DOI: 10.1073/pnas.0504628102
Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006;103:5947-5952 - PMID: 16585505 - PMCID: PMC1458678 - DOI: 10.1073/pnas.0601273103
Swirski FK, Pittet MJ, Kircher MF, Aikawa E, Jaffer FA, Libby P, Weissleder R Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A. 2006;103(27):10340-5 - PMID: 16801531 - PMCID: PMC1502459 - DOI: 10.1073/pnas.0604260103
Fulci G, Breymann L,Gianni D, Kurozomi K, Rhee S, Yu J, Kaur B, Louis D, Weissleder R, Caligiuri M, Chiocca A. Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses Proc Natl Acad Sci U S A. 2006;103:12873-12878 - PMID: 16908838 - PMCID: PMC1568940 - DOI: 10.1073/pnas.0605496103
Finberg KE, Wagner CA, Bailey MA, Paunescu TG, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A. 2005;102(38):13616-21 - PMID: 16174750 - PMCID: PMC1224669 - DOI: 10.1073/pnas.0506769102
Pittet M, Grimm J, Berger C, Tamura T, Wojtkiewicz G, Nahrendorf M, Romero P, Swirski F, Weissleder R. In vivo imaging of T cell delivery to tumors after adoptive transfer therapy Proc Natl Acad Sci U S A. 2007;104:12457-12461 - PMID: 17640914 - PMCID: PMC1941490 - DOI: 10.1073/pnas.0704460104
Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A. 2007;104:19977-82 - PMID: 18077429 - PMCID: PMC2148408 - DOI: 10.1073/pnas.0704620104
Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A. 2008;105:7387-7392 - PMID: 18492802 - PMCID: PMC2396702 - DOI: 10.1073/pnas.0802878105
Gold L, Brown D, He Y, Shtatland T, Singer B, Wu Y From oligonucleotide shapes to genomic SELEX: novel biological regulatory loops. Proc Natl Acad Sci U S A. 1997;94:59-64 - PMID: 8990161 - PMCID: PMC19236 - DOI: 10.1073/pnas.94.1.59
Hahn C, Ross K, Warrington I, Mazitschek R, Kanegai C, Wright R, Kung A, Golub T, Stegmaier K Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation. Proc Natl Acad Sci U S A. 2008;105(28):9751-6 - PMID: 18607002 - PMCID: PMC2474517 - DOI: 10.1073/pnas.0710413105
Shaw S, Wang J Chirality of DNA trefoils: implications in intramolecular synapsis of distant DNA segments. Proc Natl Acad Sci U S A. 1997;94(5):1692-7 - PMID: 9050840 - PMCID: PMC19978 - DOI: 10.1073/pnas.94.5.1692
Breckwoldt M*, Chen JW*, Stangenberg L, Aikawa E, Rodriguez E, Qiu S, Moskowitz M, Weissleder R Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase Proc Natl Acad Sci U S A. 2008;105 (47):18584-18589 - PMID: 19011099 - PMCID: PMC2587593 - DOI: 10.1073/pnas.0803945105
Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. Proc Natl Acad Sci U S A. 2008;105(49)::19126-19131 - PMID: 19015534 - PMCID: PMC2614726 - DOI: 10.1073/pnas.0804798105
Okazaki M, Ferrandon S, Vilardaga J, Bouxsein M, Potts J, Gardella T Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A. 2008;105(43):16525-30 - PMID: 18946036 - PMCID: PMC2571912 - DOI: 10.1073/pnas.0808750105
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Bronson R, Chen J, Weissleder R, Housman D, Charest A. Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene function in gliomagenesis Proc Natl Acad Sci U S A. 0;:ePub
Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proc Natl Acad Sci U S A. 2009;106(8):2712-6 - PMID: 19196966 - PMCID: PMC2650331 - DOI: 10.1073/pnas.0813314106
Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci U S A. 2009;106(12):4822-7 - PMID: 19264968 - PMCID: PMC2660771 - DOI: 10.1073/pnas.0806647106
Butcher R, Ragains J, Li W, Ruvkun G, Clardy J, Mak H Biosynthesis of the Caenorhabditis elegans dauer pheromone. Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283 - DOI: 10.1073/pnas.0810338106
Kroh H, Panizzi P, Bock P Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin. Proc Natl Acad Sci U S A. 2009;106(19):7786-91 - PMID: 19416890 - PMCID: PMC2683071 - DOI: 10.1073/pnas.0811750106
Lee H*, Yoon TJ*, Figueiredo JL, Swirski FK, Weissleder R Rapid detection and profiling of cancer cells in fine-needle aspirates. Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371 - DOI: 10.1073/pnas.0902365106
Yoo B, Gredler R, Vozhilla N, Su Z, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher P, Sarkar D Identification of genes conferring resistance to 5-fluorouracil. Proc Natl Acad Sci U S A. 2009;106(31):12938-43 - PMID: 19622726 - PMCID: PMC2722317 - DOI: 10.1073/pnas.0901451106
Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects. Proc Natl Acad Sci U S A. 2009;106(35):14932-6 - PMID: 19706423 - PMCID: PMC2736449 - DOI: 10.1073/pnas.0902408106
Evans C, Potma E, Puoris'haag M, C Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy. Proc Natl Acad Sci U S A. 2005;102:16807-12 - PMID: 16263923 - PMCID: PMC1283840 - DOI: 10.1073/pnas.0508282102
Higgins JM, Eddington DT, Bhatia SN, Mahadevan L Sickle cell vasoocclusion and rescue in a microfluidic device. Proc Natl Acad Sci U S A. 2007;104(51):20496-500 - PMID: 18077341 - PMCID: PMC2154459 - DOI: 10.1073/pnas.0707122105
Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc Natl Acad Sci U S A. 2010;107(4):1565-70 - PMID: 20080688 - PMCID: PMC2824379 - DOI: 10.1073/pnas.0908682107
Tsigkou O, Pomerantseva I, Spencer JA, Redondo PA, Hart AR, O'Doherty E, Lin Y, Friedrich CC, Daheron L, Lin CP, Sundback CA, Vacanti JP, Neville C Regenerative Medicine Special Feature: Engineered vascularized bone grafts. Proc Natl Acad Sci U S A. 2010;107(8):3311-6 - PMID: 20133604 - PMCID: PMC2840421 - DOI: 10.1073/pnas.0905445107
Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Patel K, Sohani AR, Guimaraes A, Xie W, Chauhan D, Schoonmaker JA, Attar E, Churchill M, Weller E, Munshi N, Seehra JS, Weissleder R, Anderson KC, Scadden DT, Raje N Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proc Natl Acad Sci U S A. 2010;107(11):5124-9 - PMID: 20194748 - PMCID: PMC2841922 - DOI: 10.1073/pnas.0911929107
Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R Hybrid PET-optical imaging using targeted probes Proc Natl Acad Sci U S A. 2010;107(17):7910-5 - PMID: 20385821 - PMCID: PMC2867879 - DOI: 10.1073/pnas.0915163107
Bradner JE, Mak R, Tanguturi SK, Mazitschek R, Haggarty SJ, Ross K, Chang CY, Bosco J, West N, Morse E, Lin K, Shen JP, Kwiatkowski NP, Gheldof N, Dekker J, Deangelo DJ, Carr SA, Schreiber SL, Golub TR, Ebert BL Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease. Proc Natl Acad Sci U S A. 2010;107(28):12617-22 - PMID: 20616024 - PMCID: PMC2906581 - DOI: 10.1073/pnas.1006774107
Higgins JM, Mahadevan L Physiological and pathological population dynamics of circulating human red blood cells. Proc Natl Acad Sci U S A. 2010;107(47):20587-92 - PMID: 21059904 - PMCID: PMC2996693 - DOI: 10.1073/pnas.1012747107
Gao X, Eladari D, Leviel F, Tew BY, Miro-Julia Deletion of hensin/DMBT1 blocks conversion of {beta}- to {alpha}-intercalated cells and induces distal renal tubular acidosis. Proc Natl Acad Sci U S A. 2010;107(50):21872-7 - PMID: 21098262 - PMCID: PMC3003085 - DOI: 10.1073/pnas.1010364107
Shaw SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A, Schreiber SL Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A. 2010;108(2):492-7 - PMID: 21183721 - PMCID: PMC3021060 - DOI: 10.1073/pnas.1016789108
Grover WH, Bryan AK, Diez-Silva M, Suresh S, Higgins JM, Manalis SR Measuring single-cell density. Proc Natl Acad Sci U S A. 2011;108(27):10992-10996 - PMID: 21690360 - PMCID: PMC3131325 - DOI: 10.1073/pnas.1104651108
Wang H, Zou J, Zhao B, Johannsen E, Ashworth T, Wong H, Pear WS, Schug J, Blacklow SC, Arnett KL, Bernstein BE, Kieff E, Aster JC Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. Proc Natl Acad Sci U S A. 2011;108(36):14908-13 - PMID: 21737748 - PMCID: PMC3169118 - DOI: 10.1073/pnas.1109023108
Zhao B, Zou J, Wang H, Johannsen E, Peng CW, Quackenbush J, Mar JC, Morton CC, Freedman ML, Blacklow SC, Aster JC, Bernstein BE, Kieff E Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth. Proc Natl Acad Sci U S A. 2011;108(36):14902-7 - PMID: 21746931 - PMCID: PMC3169132 - DOI: 10.1073/pnas.1108892108
Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R Accurate measurement of pancreatic islet {beta}-cell mass using a second-generation fluorescent exendin-4 analog. Proc Natl Acad Sci U S A. 2011;108(31):12815-20 - PMID: 21768367 - PMCID: PMC3150928 - DOI: 10.1073/pnas.1109859108
Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ Origins of tumor-associated macrophages and neutrophils. Proc Natl Acad Sci U S A. 2012;109(7):2491-6 - PMID: 22308361 - PMCID: PMC3289379 - DOI: 10.1073/pnas.1113744109
Devaraj NK, Thurber GM, Keliher EJ, Marinelli B, Weissleder R Reactive polymer enables efficient in vivo bioorthogonal chemistry. Proc Natl Acad Sci U S A. 2012;109(13):4762-7 - PMID: 22411831 - PMCID: PMC3324005 - DOI: 10.1073/pnas.1113466109
Fukuda D, Aikawa E, Swirski FK, Novobrantseva TI, Kotelianski V, Gorgun CZ, Chudnovskiy A, Yamazaki H, Croce K, Weissleder R, Aster JC, Hotamisligil GS, Yagita H, Aikawa M Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. Proc Natl Acad Sci U S A. 2012;109(27):E1868-77 - PMID: 22699504 - PMCID: PMC3390871 - DOI: 10.1073/pnas.1116889109
Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, Yarmush ML, Parekkadan B Implantable microenvironments to attract hematopoietic stem/cancer cells. Proc Natl Acad Sci U S A. 2012;109(48):19638-43 - PMID: 23150542 - PMCID: PMC3511730 - DOI: 10.1073/pnas.1208384109
Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, Siegel CD, Macdougall S, Okonkwo M, Thai A, Stone JR, Coury AJ, Weissleder R, Langer R, Anderson DG Painting blood vessels and atherosclerotic plaques with an adhesive drug depot. Proc Natl Acad Sci U S A. 2012;109(52):21444-9 - PMID: 23236189 - PMCID: PMC3535589 - DOI: 10.1073/pnas.1217972110
Liu Y, Shoji-Kawata S, Sumpter RM, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. Proc Natl Acad Sci U S A. 2013;110(51):20364-71 - PMID: 24277826 - PMCID: PMC3870705 - DOI: 10.1073/pnas.1319661110
Peterson VM*, Castro CM*, Chung J, Miller NC, Ullal AV, Castano MD, Penson RT, Lee H, Birrer MJ, Weissleder R Ascites analysis by a microfluidic chip allows tumor-cell profiling Proc Natl Acad Sci U S A. 2013;110(51):E4978-86 - PMID: 24297935 - PMCID: PMC3870756 - DOI: 10.1073/pnas.1315370110
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A. 2014;111(17):6131-6138 - PMID: 24753594 - PMCID: PMC4035993 - DOI: 10.1073/pnas.1318948111
Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut. Proc Natl Acad Sci U S A. 2014;111(18):6696-701 - PMID: 24753589 - PMCID: PMC4020091 - DOI: 10.1073/pnas.1405634111
Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proc Natl Acad Sci U S A. 2014;111(31):11419-24 - PMID: 25049388 - PMCID: PMC4128122 - DOI: 10.1073/pnas.1410854111
Aguirre AD, Vinegoni C, Sebas M, Weissleder R Intravital imaging of cardiac function at the single-cell level. Proc Natl Acad Sci U S A. 2014;111(31):11257-62 - PMID: 25053815 - PMCID: PMC4128110 - DOI: 10.1073/pnas.1401316111
Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos J, Weng Z, White KP, Hardison RC Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. Proc Natl Acad Sci U S A. 2014;111(33):E3366 - PMID: 25275169 - PMCID: PMC4143047 - DOI: 10.1073/pnas.1410434111
Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proc Natl Acad Sci U S A. 2014;111(46):E4946-53 - PMID: 25369933 - PMCID: PMC4246292 - DOI: 10.1073/pnas.1407079111
Magnuson AM, Thurber GM, Kohler RH, Weissleder R, Mathis D, Benoist C Population dynamics of islet-infiltrating cells in autoimmune diabetes. Proc Natl Acad Sci U S A. 2015;112(5):1511-6 - PMID: 25605891 - PMCID: PMC4321317 - DOI: 10.1073/pnas.1423769112
Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C Mathis D, Weissleder R Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients Proc Natl Acad Sci U S A. 2015;112(7):2139-44 - PMID: 25650428 - PMCID: PMC4343112 - DOI: 10.1073/pnas.1424993112
Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R*, Lee H* Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone Proc Natl Acad Sci U S A. 2015;112(18):5613-8 - PMID: 25870273 - PMCID: PMC4426451 - DOI: 10.1073/pnas.1501815112
Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL Noninvasive imaging of immune responses. Proc Natl Acad Sci U S A. 2015;112(19):6146-51 - PMID: 25902531 - PMCID: PMC4434737 - DOI: 10.1073/pnas.1502609112
Di Caprio G, Stokes C, Higgins JM, Schonbrun E Single-cell measurement of red blood cell oxygen affinity. Proc Natl Acad Sci U S A. 2015;112(32):9984-9 - PMID: 26216973 - PMCID: PMC4538663 - DOI: 10.1073/pnas.1509252112
Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer. Proc Natl Acad Sci U S A. 2015;112(32):E4418-27 - PMID: 26216943 - PMCID: PMC4538667 - DOI: 10.1073/pnas.1510604112
Weissleder R, Nahrendorf M Advancing biomedical imaging Proc Natl Acad Sci U S A. 2015;112(47):14424-8 - PMID: 26598657 - PMCID: PMC4664297 - DOI: 10.1073/pnas.1508524112
Miller MA, Meyer AS, Beste MT, Lasisi Z, Reddy S, Jeng KW, Chen CH, Han J, Isaacson K, Griffith LG, Lauffenburger DA ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling. Proc Natl Acad Sci U S A. 2013;110(22):E2074-83 - PMID: 23674691 - PMCID: PMC3670354 - DOI: 10.1073/pnas.1222387110
Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways. Proc Natl Acad Sci U S A. 2013;110(24):9776-81 - PMID: 23720309 - PMCID: PMC3683718 - DOI: 10.1073/pnas.1307478110
Naxerova K, Brachtel E, Salk JJ, Seese AM, Power K, Abbasi B, Snuderl M, Chiang S, Kasif S, Jain RK Hypermutable DNA chronicles the evolution of human colon cancer. Proc Natl Acad Sci U S A. 2014;111(18):E1889-98 - PMID: 24753616 - PMCID: PMC4020055 - DOI: 10.1073/pnas.1400179111
Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. Proc Natl Acad Sci U S A. 2012;109(41):16618-23 - PMID: 22996328 - PMCID: PMC3478596 - DOI: 10.1073/pnas.1117610109
Lau KS, Cortez-Retamozo V, Philips SR, Pittet MJ, Lauffenburger DA, Haigis KM Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium PLoS Biol. 2012;10(9):e1001393 - PMID: 23055830 - PMCID: PMC3463506 - DOI: 10.1371/journal.pbio.1001393
Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ Implantable diagnostic device for cancer monitoring. Biosens Bioelectron. 2009;24(11):3252-7 - PMID: 19442510 - PMCID: PMC2738970 - DOI: 10.1016/j.bios.2009.04.010
Kelloff GJ, Krohn KA, Larson SM, Weissleder R, Mankoff DA, Hoffman JM, Link JM, Guyton KZ, Eckelman WC, Scher HI, O The progress and promise of molecular imaging probes in oncologic drug development. Clin Cancer Res. 2005;11(22):7967-85 - PMID: 16299226 - DOI: 10.1158/1078-0432.CCR-05-1302
Ayyoub M, Zippelius A, Pittet M, Rimoldi D, Valmori D, Cerottini J, Romero P, Lejeune F, Lienard D, Speiser D Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1. Clin Cancer Res. 2003;9:669-77 - PMID: 12576434
Pittet M, Speiser D, Lienard D, Valmori D, Guillaume P, Dutoit V, Rimoldi D, Lejeune F, Cerottini J, Romero P Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide. Clin Cancer Res. 2001;7:796s-803s - PMID: 11300475
Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK Regression of drug-resistant lung cancer by the combination of rosiglitazone and Carboplatin. Clin Cancer Res. 2008;14(20):6478-86 - PMID: 18927287 - PMCID: PMC2696122 - DOI: 10.1158/1078-0432.CCR-08-1128
Kleijn A*, Chen JW*, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clin Cancer Res. 2011;17(13):4484-93 - PMID: 21558403 - PMCID: PMC3131449 - DOI: 10.1158/1078-0432.CCR-11-0575
Bazzaro M, Lin Z, Santillan A, Lee MK, Wang MC, Chan KC, Bristow RE, Mazitschek R, Bradner J, Roden RB Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor. Clin Cancer Res. 2008;14(22):7340-7 - PMID: 19010849 - PMCID: PMC2744414 - DOI: 10.1158/1078-0432.CCR-08-0642
Pucci F, Pittet MJ Molecular Pathways: Tumor-derived microvesicles and their interactions with immune cells in vivo. Clin Cancer Res. 2013;19(10):2598-604 - PMID: 23426276 - PMCID: PMC3655093 - DOI: 10.1158/1078-0432.CCR-12-0962
Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Desphande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes CH, Engelman JA, Bardeesy N Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer. Clin Cancer Res. 2014;21(2):396-404 - PMID: 25348516 - PMCID: PMC4447091 - DOI: 10.1158/1078-0432.CCR-14-1591
Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clin Cancer Res. 2011;17(11):3638-48 - PMID: 21459800 - PMCID: PMC3107920 - DOI: 10.1158/1078-0432.CCR-10-2456
Wu CY, Yang LH, Yang HY, Knoff J, Peng S, Lin YH, Wang C, Alvarez RD, Pai SI, Roden RB, Hung CF, Wu TC Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors. Clin Cancer Res. 2013;20(3):644-57 - PMID: 24300786 - PMCID: PMC3946442 - DOI: 10.1158/1078-0432.CCR-13-1334
Chuang CM, Monie A, Wu A, Pai SI, Hung CF Combination of viral oncolysis and tumor-specific immunity to control established tumors. Clin Cancer Res. 2009;15(14):4581-8 - PMID: 19584165 - PMCID: PMC3076709 - DOI: 10.1158/1078-0432.CCR-08-2685
Ha PK, Pai SI, Westra WH, Gillison ML, Tong BC, Sidransky D, Califano JA Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res. 2002;8(5):1203-9 - PMID: 12006539
Capone RB, Pai SI, Koch WM, Gillison ML, Danish HN, Westra WH, Daniel R, Shah KV, Sidransky D Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma. Clin Cancer Res. 2000;6(11):4171-5 - PMID: 11106228
Shah K, Russinova E, Gadella T, Willemse J, De Vries S The Arabidopsis kinase-associated protein phosphatase controls internalization of the somatic embryogenesis receptor kinase 1. Gene Dev. 2002;16(13):1707-20 - PMID: 12101128 - PMCID: PMC186368 - DOI: 10.1101/gad.220402
de Sousa Lopes S, Roelen B, Monteiro R, Emmens R, Lin HY, Li E, Lawson K, Mummery C BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Gene Dev. 2004;18(15):1838-49 - PMID: 15289457 - PMCID: PMC517404 - DOI: 10.1101/gad.294004
Li G, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D Jarid2 and PRC2, partners in regulating gene expression. Gene Dev. 2010;24(4):368-80 - PMID: 20123894 - PMCID: PMC2816736 - DOI: 10.1101/gad.1886410
Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Gene Dev. 2012;26(24):2802-16 - PMID: 23249739 - PMCID: PMC3533082 - DOI: 10.1101/gad.207142.112
Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D. Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes J Clin Invest. 2005;115(9):2454-2461 - PMID: 16110329 - PMCID: PMC1187933 - DOI: 10.1172/JCI25048
Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata J Clin Invest. 2007;117(1):195-205 - PMID: 17200719 - PMCID: PMC1716211 - DOI: 10.1172/JCI29950
Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest. 2007;117(7):1933-1939 - PMID: 17607365 - PMCID: PMC1904317 - DOI: 10.1172/JCI31342
Ducharme A, Frantz S, Aikawa M, Rabkin E, Lindsey M, Rohde L, Schoen F, Kelly R, Werb Z, Libby P, Lee R Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest. 2000;106:55-62 - PMID: 10880048 - PMCID: PMC517910 - DOI: 10.1172/JCI8768
Laufs U, Endres M, Stagliano N, Amin-Hanjani S, Chui D, Yang S, Simoncini T, Yamada M, Rabkin E, Allen P, Huang P, Bahm M, Schoen F, Moskowitz M, Liao J Neuroprotection mediated by changes in the endothelial actin cytoskeleton. J Clin Invest. 2000;106:15-24 - PMID: 10880044 - PMCID: PMC314365 - DOI: 10.1172/JCI9639
Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation J Clin Invest. 2008;118(12):4058-66 - PMID: 19033674 - PMCID: PMC2579705 - DOI: 10.1172/JCI36335
Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008;:ePub - PMID: 19005570 - PMCID: PMC2579884
Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. J Clin Invest. 2009;119(11):3322-8 - PMID: 19809161 - PMCID: PMC2769199 - DOI: 10.1172/JCI39939
Ueno T, Habicht A, Clarkson MR, Albin MJ, Yamaura K, Boenisch O, Popoola J, Wang Y, Yagita H, Akiba H, Ansari MJ, Yang J, Turka LA, Rothstein DM, Padera RF, Najafian N, Sayegh MH The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest. 2008;118(2):742-51 - PMID: 18172549 - PMCID: PMC2157561 - DOI: 10.1172/JCI32451
Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice. J Clin Invest. 2010;120(7):2627-34 - PMID: 20577051 - PMCID: PMC2898607 - DOI: 10.1172/JCI42304
Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. J Clin Invest. 2010;121(1):442-5 - PMID: 21123946 - PMCID: PMC3007157 - DOI: 10.1172/JCI44339
Bouley R, Breton S, Sun T, McLaughlin M, Nsumu NN, Lin HY, Ausiello DA, Brown D Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells. J Clin Invest. 2000;106(9):1115-26 - PMID: 11067864 - PMCID: PMC301414 - DOI: 10.1172/JCI9594
Choukroun GJ, Marshansky V, Gustafson CE, McKee M, Hajjar RJ, Rosenzweig A, Brown D, Bonventre JV Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins. J Clin Invest. 2000;106(8):983-93 - PMID: 11032858 - PMCID: PMC314339 - DOI: 10.1172/JCI8914
Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V Evidence for bistable bacteria-neutrophil interaction and its clinical implications. J Clin Invest. 2012;122(8):3002-11 - PMID: 22820292 - PMCID: PMC3408731 - DOI: 10.1172/JCI59832
Pittet M, Mempel T Regulation of T Cell Migration and Effector Functions-Insights from in Vivo Imaging Studies Immunol Rev. 2007;:ePub
Pittet MJ, Mempel TR Regulation of T-cell migration and effector functions: insights from in vivo imaging studies. Immunol Rev. 2008;221:107-29 - PMID: 18275478 - DOI: 10.1111/j.1600-065X.2008.00584.x
Romero P, Valmori D, Pittet M, Zippelius A, Rimoldi D, Levy F, Dutoit V, Ayyoub M, Rubio-Godoy V, Michielin O, Guillaume P, Batard P, Luescher I, Lejeune F, Lienard D, Rufer N, Dietrich P, Speiser D, Cerottini J Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev. 2002;188:81-96 - PMID: 12445283 - DOI: 10.1034/j.1600-065x.2002.18808.x
Dutta P, Nahrendorf M Regulation and consequences of monocytosis. Immunol Rev. 2014;262(1):167-78 - PMID: 25319334 - PMCID: PMC4203415 - DOI: 10.1111/imr.12219
Perez JM, Simeone FJ, Tsourkas A, Josephson L, Weissleder R Peroxidase substrate nanosensors for MR imaging Nano Lett. 0;4:119-122
McCarthy JR, Perez JM, Brueckner C, Weissleder R Polymeric Nanoparticle Preparation that Eradicates Tumors. Nano Lett. 2005;5:2552-6 - PMID: 16351214 - DOI: 10.1021/nl0519229
Quinti L, Weissleder R, Tung CH A Fluorescent Nanosensor for Apoptotic Cells Nano Lett. 2006;6 (3):488-490 - PMID: 16522048 - DOI: 10.1021/nl0524694
Lee H, Purdon AM, Chu V, Westervelt RM Controlled Assembly of Magnetic Nanoparticles from Magnetotactic Bacteria Using Microelectromagnets Arrays Nano Lett. 0;4(5):995
Ghosh K, Kanapathipillai M, Korin N, McCarthy JR, Ingber D Polymeric Nanomaterials for Islet Targeting and Immunotherapeutic Delivery. Nano Lett. 2011;12(1):203-8 - PMID: 22196766 - PMCID: PMC3280082 - DOI: 10.1021/nl203334c
Xu C, Miranda-Nieves D, Ankrum JA, Matthiesen ME, Phillips J, Roes I, Wojtkiewicz GR, Juneja V, Kultima JR, Zhao W, Vemula PK, Lin CP, Nahrendorf M, Karp JM Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticle Loaded Poly(lactide-co-glycolide) Microparticles. Nano Lett. 2012;12(8):4131-9 - PMID: 22769232 - PMCID: PMC3552518 - DOI: 10.1021/nl301658q
Epa VC, Burden FR, Tassa C, Weissleder R, Shaw SY, Winkler DA Modelling biological activities of nanoparticles. Nano Lett. 2012;12(11):5808-5812 - PMID: 23039907 - DOI: 10.1021/nl303144k
Im H, Bantz KC, Lindquist NC, Haynes CL, Oh SH Vertically oriented sub-10-nm plasmonic nanogap arrays. Nano Lett. 2010;10(6):2231-6 - PMID: 20499849 - DOI: 10.1021/nl1012085
Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, Charollais A, Ramadori P, Foti M, Meda P, Féraille E, Brown D, Hasler U Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Autophagy. 2013;9(4):550-67 - PMID: 23380587 - PMCID: PMC3627670 - DOI: 10.4161/auto.23662
Corradini E, Meynard D, Wu Q, Chen S, Ventura P, Pietrangelo A, Babitt JL Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice. Hepatology. 2011;54(1):273-84 - PMID: 21488083 - PMCID: PMC3277401 - DOI: 10.1002/hep.24359
Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg F, Weissleder R, Carson W, Chiocca A, Kaur B. Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy J Natl Cancer Inst. 2007;(99) 23:1768-1781 - PMID: 18042934 - DOI: 10.1093/jnci/djm229
Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, Huang P, Fukumura D, Engelman JA, Jain RK Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. J Natl Cancer Inst. 2015;108(2):ePub - PMID: 26547932 - PMCID: PMC4862418 - DOI: 10.1093/jnci/djv313
Shao H, Min C, Issadore D, Liong M, Yoon TJ, Weissleder R, Lee H Magnetic Nanoparticles and microNMR for Diagnostic Applications. Theranostics. 2012;2(1):55-65 - PMID: 22272219 - PMCID: PMC3263516 - DOI: 10.7150/thno.3465
Shan G, Weissleder R, Hilderbrand SA Upconverting Organic Dye Doped Core-Shell Nano-Composites for Dual-Modality NIR Imaging and Photo-Thermal Therapy. Theranostics. 2013;3(4):267-74 - PMID: 23606913 - PMCID: PMC3630527 - DOI: 10.7150/thno.5226
Wildgruber M, Swirski FK, Zernecke A Molecular Imaging of Inflammation in Atherosclerosis. Theranostics. 2013;3(11):865-884 - PMID: 24312156 - PMCID: PMC3841337 - DOI: 10.7150/thno.5771
Yoon YI, Kwon YS, Cho HS, Heo SH, Park KS, Park SG, Lee SH, Hwang SI, Kim YI, Jae HJ, Ahn GJ, Cho YS, Lee H*, Lee HJ*, Yoon TJ* Ultrasound-Mediated Gene and Drug Delivery Using a Microbubble-Liposome Particle System Theranostics. 2014;4(11):1133-1144
Turetsky A, Lee K, Song J, Giedt RJ, Kim E, Kovach AE, Hochberg EP, Castro CM, Lee H, Weissleder R On chip analysis of CNS lymphoma in cerebrospinal fluid. Theranostics. 2015;5(8):796-804 - PMID: 26000053 - PMCID: PMC4440438 - DOI: 10.7150/thno.11220
Kim JY, Ryu JH, Schellingerhout D, Sun IC, Lee SK, Jeon S, Kim J, Kwon IC, Nahrendorf M, Ahn CH, Kim K, Kim DE Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles. Theranostics. 2015;5(10):1098-114 - PMID: 26199648 - PMCID: PMC4508499 - DOI: 10.7150/thno.11679
Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study. Theranostics. 2015;5(12):1317-27 - PMID: 26516370 - PMCID: PMC4615735 - DOI: 10.7150/thno.12494
Marshansky V, Futai M The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function. Curr Opin Cell Biol. 2008;20(4):415-26 - PMID: 18511251 - PMCID: PMC7111286 - DOI: 10.1016/j.ceb.2008.03.015
Kumar V, Donahue DM, Patel N An unexpected complication during cardiac catheterization: blood clot cast of the tracheobronchial tree: first case during cardiac catheterization. JACC Cardiovasc Interv. 2013;6(4):e19 - PMID: 23597616 - DOI: 10.1016/j.jcin.2012.11.007
Zeng X, Zou L, Levine RA, Guerrero JL, Handschumacher MD, Sullivan SM, Braithwaite GJ, Stone JR, Solis J, Muratoglu OK, Vlahakes GJ, Hung J Efficacy of Polymer Injection for Ischemic Mitral Regurgitation: Persistent Reduction of Mitral Regurgitation and Attenuation of Left Ventricular Remodeling. JACC Cardiovasc Interv. 2015;8(2):355-63 - PMID: 25596792 - PMCID: PMC5645299 - DOI: 10.1016/j.jcin.2014.09.016
Shah K, Bureau E, Kim DE, Yang K, Tang Y, Weissleder R, Breakefield XO. Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression Ann Neurol. 2005;57(1):34-41 - PMID: 15622535 - DOI: 10.1002/ana.20306
Johnson J, Wiley R, Fattouh R, Swirski F, Gajewska B, Coyle A, Gutierrez-Ramos J, Ellis R, Inman M, Jordana M Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am J Resp Crit Care. 2004;169(3):378-85 - PMID: 14597485 - DOI: 10.1164/rccm.200308-1094OC
Ntziachristos V Fluorescence Molecular Imaging. Annu Rev Biomed Eng. 2006;8:1-33 - PMID: 16834550 - DOI: 10.1146/annurev.bioeng.8.061505.095831
Nahrendorf M, Spindler M, Hu K, Bauer L, Ritter O, Nordbeck P, Quaschning T, Hiller K, Wallis J, Ertl G, Bauer W, Neubauer S Creatine kinase knockout mice show left ventricular hypertrophy and dilatation, but unaltered remodeling post-myocardial infarction. Cardiovasc Res. 2005;65(2):419-27 - PMID: 15639481 - DOI: 10.1016/j.cardiores.2004.10.006
Nahrendorf M, Frantz S, Hu K, von zur Mahlen C, Tomaszewski M, Scheuermann H, Kaiser R, Jazbutyte V, Beer S, Bauer W, Neubauer S, Ertl G, Allolio B, Callies F Effect of testosterone on post-myocardial infarction remodeling and function. Cardiovasc Res. 2003;57(2):370-8 - PMID: 12566109 - DOI: 10.1016/s0008-6363(02)00701-0
Pelzer T, Jazbutyte V, Hu K, Segerer S, Nahrendorf M, Nordbeck P, Bonz AW, Muck J, Fritzemeier KH, Hegele-Hartung C, Ertl G, Neyses L The estrogen receptor-alpha agonist 16alpha-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats. Cardiovasc Res. 2005;67(4):604-12 - PMID: 15950203 - DOI: 10.1016/j.cardiores.2005.04.035
Hu K, Gaudron P, Anders HJ, Weidemann F, Turschner O, Nahrendorf M, Ertl G Chronic effects of early started angiotensin converting enzyme inhibition and angiotensin AT1-receptor subtype blockade in rats with myocardial infarction: role of bradykinin. Cardiovasc Res. 1998;39(2):401-12 - PMID: 9798525 - DOI: 10.1016/s0008-6363(98)00090-x
Frantz S, Nahrendorf M Cardiac macrophages and their role in ischemic heart disease. Cardiovasc Res. 2014;102(2):240-8 - PMID: 24501331 - PMCID: PMC3989449 - DOI: 10.1093/cvr/cvu025
Mendenhall EM, Bernstein BE DNA-protein interactions in high definition. Genome Biol. 2012;13(1):139 - PMID: 22283870 - PMCID: PMC3334573 - DOI: 10.1186/gb-2012-13-1-139
Ku M, Jaffe JD, Koche RP, Rheinbay E, Endoh M, Koseki H, Carr SA, Bernstein BE H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions. Genome Biol. 2012;13(10):R85 - PMID: 23034477 - PMCID: PMC3491413 - DOI: 10.1186/gb-2012-13-10-r85
Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF A genomic and evolutionary approach reveals non-genetic drug resistance in malaria. Genome Biol. 2014;15(11):511 - PMID: 25395010 - PMCID: PMC4272547 - DOI: 10.1186/PREACCEPT-1067113631444973
Naxerova K, Bult CJ, Peaston A, Fancher K, Knowles BB, Kasif S, Kohane IS Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers. Genome Biol. 2008;9(7):R108 - PMID: 18611264 - PMCID: PMC2530866 - DOI: 10.1186/gb-2008-9-7-r108
Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura N, Ohguchi H, Cottini F, Jakubikova J, Munshi NC, Haggarty SJ, Richardson PG, Hideshima T, Anderson KC Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma. Leukemia. 2013;28(3):680-9 - PMID: 23913134 - PMCID: PMC4165599 - DOI: 10.1038/leu.2013.231
Hideshima T, Mazitschek R, Santo L, Mimura N, Gorgun G, Richardson PG, Raje N, Anderson KC Induction of differential apoptotic pathways in multiple myeloma cells by class selective histone deacetylase inhibitors. Leukemia. 2013;28(2):457-60 - PMID: 24150220 - PMCID: PMC4405100 - DOI: 10.1038/leu.2013.301
Eda H, Santo L, Cirstea DD, Yee AJ, Scullen TA, Nemani N, Mishima Y, Waterman PR, Arastu-Kapur S, Evans E, Singh J, Kirk CJ, Westlin WF, Raje NS A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity. Leukemia. 2014;28(9):1892-901 - PMID: 24518207 - DOI: 10.1038/leu.2014.69
Touhami M, Fauvel-Lafève F, Da Silva N, Chomienne C, Legrand C Induction of thrombospondin-1 by all-trans retinoic acid modulates growth and differentiation of HL-60 myeloid leukemia cells. Leukemia. 1997;11(12):2137-42 - PMID: 9447832 - DOI: 10.1038/sj.leu.2400866
Gruss HJ, DaSilva N, Hu ZB, Uphoff CC, Goodwin RG, Drexler HG Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines. Leukemia. 1994;8(12):2083-94 - PMID: 7528856
DaSilva N, Hu ZB, Ma W, Rosnet O, Birnbaum D, Drexler HG Expression of the FLT3 gene in human leukemia-lymphoma cell lines. Leukemia. 1994;8(5):885-8 - PMID: 8182945
Chen W, Sun CC, Chen S, Meynard D, Babitt JL, Lin HY A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum. Haematologica. 2012;98(2):296-304 - PMID: 22875629 - PMCID: PMC3561439 - DOI: 10.3324/haematol.2012.070136
Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX Stress-induced hematopoietic failure in the absence of immediate early response gene X-1. Haematologica. 2013;99(2):282-91 - PMID: 24056813 - PMCID: PMC3912958 - DOI: 10.3324/haematol.2013.092452
Chung J*, Shao H*, Reiner T, Issadore D, Weissleder R, Lee H Cell Sorting: Microfluidic Cell Sorter (μFCS) for On-chip Capture and Analysis of Single Cells Adv Healthc Mater. 2012;1(4):432-6 - PMID: 23184773 - PMCID: PMC3508764 - DOI: 10.1002/adhm.201200046
Issadore D*, Chung HJ*, Chung J, Budin G, Weissleder R*, Lee H* μHall Chip for Sensitive Detection of Bacteria Adv Healthc Mater. 2013;2(9):1224-8 - PMID: 23495188 - PMCID: PMC4340655 - DOI: 10.1002/adhm.201200380
Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H*, Weissleder R* Magnetic Ligation Method for Quantitative Detection of MicroRNAs. Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040 - DOI: 10.1002/adhm.201300672
Hong S, Carlson J, Lee H, Weissleder R Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking. Adv Healthc Mater. 2015;5(4):421-426 - PMID: 26688173 - PMCID: PMC4811597 - DOI: 10.1002/adhm.201500780
Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis. Brain. 2008;131(Pt 4):1123-33 - PMID: 18234693 - PMCID: PMC4044727 - DOI: 10.1093/brain/awn004
Polasek M, Fuchs BC, Uppal R, Schühle DT, Alford JK, Loving GS, Yamada S, Wei L, Lauwers GY, Guimaraes AR, Tanabe KK, Caravan P Molecular MR Imaging of Liver Fibrosis: A Feasibility Study using Rat and Mouse Models. J Hepatol. 2012;57(3):549-55 - PMID: 22634342 - PMCID: PMC3423553 - DOI: 10.1016/j.jhep.2012.04.035
Ladapo JA, Jaffer FA, Weinstein MC, Froelicher ES Projected Cost-effectiveness of Smoking Cessation Interventions in Patients Hospitalized With Myocardial Infarction. Arch Intern Med. 2011;171(1):39-45 - PMID: 21220659 - DOI: 10.1001/archinternmed.2010.479
Bogdanov A, Weissleder R The development of in vivo imaging systems to study gene expression. Trends Biotechnol. 1998;16(1):5-10 - PMID: 9470227 - DOI: 10.1016/S0167-7799(97)01150-5
Zhao M, Weissleder R Intracellular cargo delivery using tat peptide and derivatives Med Res Rev. 2004;24:1-12 - PMID: 14595670 - DOI: 10.1002/med.10056
Pittet M, Zippelius A, Valmori D, Speiser D, Cerottini J, Romero P Melan-A/MART-1-specific CD8 T cells: from thymus to tumor. Trends Immunol. 2002;23:325-8 - PMID: 12103339 - DOI: 10.1016/s1471-4906(02)02244-5
Squadrito ML, Etzrodt M, De Palma M, Pittet MJ MicroRNA-mediated control of macrophages and its implications for cancer. Trends Immunol. 2013;34(7):350-9 - PMID: 23498847 - PMCID: PMC3700601 - DOI: 10.1016/j.it.2013.02.003
Hwang WL, Marciscano AE, Niemierko A, Kim DW, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Loeffler JS, Oh KS, Shih HA, Larvie M Imaging and extent of surgical resection predict risk of meningioma recurrence better than WHO histopathological grade. Neuro Oncol. 2015;18(6):863-72 - PMID: 26597949 - PMCID: PMC4864259 - DOI: 10.1093/neuonc/nov285
Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bunemann M Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends Pharmacol Sci. 2008;29(3):159-65 - PMID: 18262662 - DOI: 10.1016/j.tips.2007.12.002
Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. 2013;73(6):1170-1175 - PMID: 23716066 - PMCID: PMC3815491 - DOI: 10.1136/annrheumdis-2012-203202
Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D Impaired Tubular Uptake Explains Albuminuria in Early Diabetic Nephropathy. J Am Soc Nephrol. 2008;20(3):489-94 - PMID: 19118149 - PMCID: PMC2653682 - DOI: 10.1681/ASN.2008050503
Izawa A*, Ueno T*, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R Importance of donor- and recipient-derived selectins in cardiac allograft rejection. J Am Soc Nephrol. 2007;18(11):2929-36 - PMID: 17928506 - DOI: 10.1681/ASN.2006111261
Ueno T, Tanaka K, Jurewicz M, Murayama T, Guleria I, Fiorina P, Paez JC, Augello A, Vergani A, Wong M, Smith RN, Abdi R Divergent role of donor dendritic cells in rejection versus tolerance of allografts. J Am Soc Nephrol. 2009;20(3):535-44 - PMID: 19129312 - PMCID: PMC2653678 - DOI: 10.1681/ASN.2008040377
Xia Y, Babitt JL, Bouley R, Zhang Y, Silva ND, Chen S, Zhuang Z, Samad TA, Brenner GJ, Anderson JL, Hong CC, Schneyer AL, Brown D, Lin HY Dragon Enhances BMP Signaling and Increases Transepithelial Resistance in Kidney Epithelial Cells. J Am Soc Nephrol. 2010;21(4):666-77 - PMID: 20167703 - PMCID: PMC2844302 - DOI: 10.1681/ASN.2009050511
Bouley R, Lu HA, Nunes P, Da Silva N, McLaughlin M, Chen Y, Brown D Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration. J Am Soc Nephrol. 2010;22(1):59-72 - PMID: 21071524 - PMCID: PMC3014035 - DOI: 10.1681/ASN.2009121267
Breton S, Marsolais M, Lapointe JY, Laprade R Cell volume increases of physiologic amplitude activate basolateral K and CI conductances in the rabbit proximal convoluted tubule. J Am Soc Nephrol. 1996;7(10):2072-87 - PMID: 8915967 - DOI: 10.1681/ASN.V7102072
Breton S, Brown D Cold-induced microtubule disruption and relocalization of membrane proteins in kidney epithelial cells. J Am Soc Nephrol. 1998;9(2):155-66 - PMID: 9527391 - DOI: 10.1681/ASN.V92155
Sabolić I, Herak-Kramberger CM, Breton S, Brown D Na/K-ATPase in intercalated cells along the rat nephron revealed by antigen retrieval. J Am Soc Nephrol. 1999;10(5):913-22 - PMID: 10232676 - DOI: 10.1681/ASN.V105913
Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Desch Pendrin regulation in mouse kidney primarily is chloride-dependent. J Am Soc Nephrol. 2006;17(8):2153-63 - PMID: 16825334 - DOI: 10.1681/ASN.2005101054
Brown D, Wagner CA Molecular Mechanisms of Acid-Base Sensing by the Kidney. J Am Soc Nephrol. 2012;23(5):774-80 - PMID: 22362904 - PMCID: PMC3338302 - DOI: 10.1681/ASN.2012010029
Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA Aquaporin 2 Promotes Cell Migration and Epithelial Morphogenesis. J Am Soc Nephrol. 2012;23(9):1506-17 - PMID: 22859853 - PMCID: PMC3431417 - DOI: 10.1681/ASN.2012010079
Babitt JL, Lin HY Mechanisms of Anemia in CKD. J Am Soc Nephrol. 2012;23(10):1631-4 - PMID: 22935483 - PMCID: PMC3458456 - DOI: 10.1681/ASN.2011111078
Brown D, Jenny Lu HA Aquaporin-2 Inhibitors: Fishing in the Chemical Pool. J Am Soc Nephrol. 2013;24(5):685-6 - PMID: 23599384 - DOI: 10.1681/ASN.2013030243
Little MH, Brown D, Humphreys BD, McMahon AP, Miner JH, Sands JM, Weisz OA, Mullins C, Hoshizaki D, Defining Kidney Biology to Understand Renal Disease. Clin J Am Soc Nephrol. 2013;9(4):809-11 - PMID: 24370769 - PMCID: PMC3974369 - DOI: 10.2215/CJN.10851013
Soehnlein O, Swirski FK Hypercholesterolemia links hematopoiesis with atherosclerosis. Trends Endocrin Met. 2012;24(3):129-136 - PMID: 23228326 - PMCID: PMC4302393 - DOI: 10.1016/j.tem.2012.10.008
Corradini E, Babitt JL, Lin HY The RGM/DRAGON family of BMP co-receptors. Cytokine Growth Factor Rev. 2009;20(5-6):389-98 - PMID: 19897400 - PMCID: PMC3715994 - DOI: 10.1016/j.cytogfr.2009.10.008
Hilderbrand SA, Weissleder R Near-infrared fluorescence: application to in vivo molecular imaging. Curr Opin Chem Biol. 2009;14:1-9 - PMID: 19879798 - DOI: 10.1016/j.cbpa.2009.09.029
Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells. eLife. 2014;3:e04631 - PMID: 25407682 - PMCID: PMC4270084 - DOI: 10.7554/eLife.04631
Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells. eLife. 2015;4:ePub - PMID: 25998054 - PMCID: PMC4441007 - DOI: 10.7554/eLife.05920
Naxerova K, Elledge SJ Taking the brakes off telomerase. eLife. 2015;4:ePub - PMID: 26194808 - PMCID: PMC4507575 - DOI: 10.7554/eLife.09519
Jochems J, Boulden J, Lee BG, Blendy JA, Jarpe M, Mazitschek R, Van Duzer JH, Berton O Antidepressant-Like Properties of Novel HDAC6 Selective Inhibitors with Improved Brain Bioavailability. Neuropsychopharmacology. 2013;39(2):389-400 - PMID: 23954848 - PMCID: PMC3870780 - DOI: 10.1038/npp.2013.207
Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas Cancer Res. 2004;64:273-8 - PMID: 14729634 - DOI: 10.1158/0008-5472.can-03-1123
Grimm J, Perez JM, Josephson L, Weissleder R Novel nanosensors for rapid analysis of telomerase activity Cancer Res. 2004;64:639-43 - PMID: 14744779 - DOI: 10.1158/0008-5472.can-03-2798
Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A Jr Near-infrared fluorescent imaging of tumor apoptosis Cancer Res. 2003;63:1936-42 - PMID: 12702586
Kircher MF, Allport, JR, Graves EE, Love V, Josephson L, Lichtman AH, Weissleder R In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors Cancer Res. 2003;63:6838-46 - PMID: 14583481
Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation Cancer Res. 2003;63:8122-5 - PMID: 14678964
Tung CH, Mahmood U, Bredow S, Weissleder R In vivo imaging of proteolytic enzyme activity using a novel molecular reporter Cancer Res. 2000;60:4953-8 - PMID: 10987312
Simonova M, Wall A, Weissleder R, Bogdanov A Jr Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells Cancer Res. 2000;60:6656-62 - PMID: 11118049
Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout D, Weissleder R In Vivo Imaging of ?-Galactosidase Activity Using Far Red Fluorescent Switch Cancer Res. 2004;64:1579-1583 - PMID: 14996712 - DOI: 10.1158/0008-5472.can-03-3226
Shah K, Tung CH, Yang K, Weissleder R, Breakefield XO Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy Cancer Res. 2004;64(9):3236-42 - PMID: 15126365 - DOI: 10.1158/0008-5472.can-03-3516
Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res. 2004;64(12):4069-77 - PMID: 15205313 - DOI: 10.1158/0008-5472.CAN-04-1243
Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res. 2004;64(17):6247-51 - PMID: 15342411 - DOI: 10.1158/0008-5472.CAN-04-0817
Montet X, Ntziachristos V, Grimm J, Weissleder R. Tomographic Fluorescence Mapping of Tumor Targets Cancer Res. 2005;65 (14):6330-6336 - PMID: 16024635 - DOI: 10.1158/0008-5472.CAN-05-0382
Tang Y, Kim M, Carrasco D, Kung AL, Chin L, Weissleder R. In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging Cancer Res. 2005;65(18):8324-30 - PMID: 16166309 - DOI: 10.1158/0008-5472.CAN-05-0027
Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA Jr. Detection of Early Antiangiogenic Effects in Human Colon Adenocarcinoma Xenografts: In vivo Changes of Tumor Blood Volume in Response to Experimental VEGFR Tyrosine Kinase Inhibitor Cancer Res. 2005;65(20):9253-60 - PMID: 16230386 - DOI: 10.1158/0008-5472.CAN-03-2619
Choi YD, Weissleder R, Tung CH. Selective antitumor effect of novel protease-mediated photodynamic agent Cancer Res. 2006;66 (14):7225-7229 - PMID: 16849570 - DOI: 10.1158/0008-5472.CAN-06-0448
Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K. Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo Cancer Res. 2007;67 (15):7335-7342 - PMID: 17671203 - DOI: 10.1158/0008-5472.CAN-07-0077
Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell Delivered S-TRAIL in Human Gliomas. Cancer Res. 2007;67(19):8994-9000 - PMID: 17908999 - DOI: 10.1158/0008-5472.CAN-07-1045
Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Rachamimov AS, Hochberg FH, Weissleder R, Martuza RL, Chiocca EA Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 2007;67(19):9398-406 - PMID: 17909049 - PMCID: PMC2850558 - DOI: 10.1158/0008-5472.CAN-07-1063
Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R Detection of early prostate cancer using a hepsin-targeted imaging agent. Cancer Res. 2008;68(7):2286-91 - PMID: 18381435 - PMCID: PMC2709884 - DOI: 10.1158/0008-5472.CAN-07-1349
Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Lienard D, Lejeune F, Rimoldi D, Guillaume P, Meidenbauer N, Mackensen A, Rufer N, Lubenow N, Speiser D, Cerottini J, Romero P, Pittet M Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res. 2004;64:2865-73 - PMID: 15087405 - DOI: 10.1158/0008-5472.can-03-3066
Meidenbauer N, Zippelius A, Pittet M, Laumer M, Vogl S, Heymann J, Rehli M, Seliger B, Schwarz S, Le Gal F, Dietrich P, Andreesen R, Romero P, Mackensen A High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res. 2004;64:6319-26 - PMID: 15342421 - DOI: 10.1158/0008-5472.CAN-04-1341
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Lienard D, Gugerli O, Ferradini L, Robert C, Avril M, Zitvogel L, Angevin E Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res. 2004;64:2192-8 - PMID: 15026362 - DOI: 10.1158/0008-5472.can-03-2969
Valmori D, Pittet M, Vonarbourg C, Rimoldi D, Lienard D, Speiser D, Dunbar R, Cerundolo V, Cerottini J, Romero P Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376. Cancer Res. 1999;59:4050-5 - PMID: 10463606
Valmori D, Dutoit V, Lienard D, Rimoldi D, Pittet M, Champagne P, Ellefsen K, Sahin U, Speiser D, Lejeune F, Cerottini J, Romero P Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients. Cancer Res. 2000;60:4499-506 - PMID: 10969798
Valmori D, Pittet M, Rimoldi D, Lienard D, Dunbar R, Cerundolo V, Lejeune F, Cerottini J, Romero P An antigen-targeted approach to adoptive transfer therapy of cancer. Cancer Res. 1999;59:2167-73 - PMID: 10232604
Kelly K, Manos E, Jensen G, Nadauld L, Jones D APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. Cancer Res. 2000;60:1021-7 - PMID: 10706119
Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors. Cancer Res. 2009;69(8):3472-81 - PMID: 19351838 - PMCID: PMC2785462 - DOI: 10.1158/0008-5472.CAN-08-3886
Georgakoudi I, Solban N, Novak J, Rice WL, Wei X, Hasan T, Lin CP In vivo flow cytometry: a new method for enumerating circulating cancer cells. Cancer Res. 2004;64(15):5044-7 - PMID: 15289300 - PMCID: PMC2824432 - DOI: 10.1158/0008-5472.CAN-04-1058
Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, Fisher PB, Sarkar D Molecular Mechanism of Chemoresistance by Astrocyte Elevated Gene-1. Cancer Res. 2010;70(8):3249-58 - PMID: 20388796 - PMCID: PMC2855753 - DOI: 10.1158/0008-5472.CAN-09-4009
Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Aleman JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR The Phosphoinositide 3-Kinase Regulatory Subunit p85{alpha} Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling. Cancer Res. 2010;70(13):5305-5315 - PMID: 20530665 - PMCID: PMC3204358 - DOI: 10.1158/0008-5472.CAN-09-3399
Bagci-Onder T, Wakimoto H, Anderegg M, Cameron C, Shah K A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell delivered TRAIL in experimental glioma models. Cancer Res. 2010;71(1):154-63 - PMID: 21084267 - DOI: 10.1158/0008-5472.CAN-10-1601
Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics. Cancer Res. 2011;71(13):4608-16 - PMID: 21712408 - PMCID: PMC3129392 - DOI: 10.1158/0008-5472.CAN-11-0412
Earley S, Vinegoni C, Dunham J, Gorbatov R, Fumene Feruglio P, Weissleder R In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single cell resolution. Cancer Res. 2012;72(12):2949-56 - PMID: 22505651 - PMCID: PMC3603290 - DOI: 10.1158/0008-5472.CAN-11-4096
Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA, A Blueprint for an International Cancer Epigenome Consortium. A Report from the AACR Cancer Epigenome Task Force. Cancer Res. 2012;72(24):6319-6324 - PMID: 23188507 - DOI: 10.1158/0008-5472.CAN-12-3658
Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari KI, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1. Cancer Res. 2013;74(3):738-50 - PMID: 24310399 - PMCID: PMC3928601 - DOI: 10.1158/0008-5472.CAN-13-2650
Viaud S, Daillère R, Boneca IG, Lepage P, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L Harnessing the Intestinal Microbiome for Optimal Therapeutic Immunomodulation. Cancer Res. 2014;74(16):4217-4221 - PMID: 25074615 - PMCID: PMC6700746 - DOI: 10.1158/0008-5472.CAN-14-0987
Chan CT, Qi J, Smith W, Paranal R, Mazitschek R, West N, Reeves R, Chiosis G, Schreiber SL, Bradner JE, Paulmurugan R, Gambhir SS Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase (HDAC) Inhibitors by Multimodality Molecular Imaging in Living Subjects. Cancer Res. 2014;74(24):7475-86 - PMID: 25320008 - PMCID: PMC4315624 - DOI: 10.1158/0008-5472.CAN-14-0197
Tesfay L, Clausen KA, Kim JW, Hedge P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV Hepcidin regulation in prostate and its disruption in prostate cancer. Cancer Res. 2015;75(11):2254-63 - PMID: 25858146 - PMCID: PMC4454355 - DOI: 10.1158/0008-5472.CAN-14-2465
Lyford-Pike S, Peng S, Young GD, Taube JM, Westra WH, Akpeng B, Bruno TC, Richmon JD, Wang H, Bishop JA, Chen L, Drake CG, Topalian SL, Pardoll DM, Pai SI Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res. 2013;73(6):1733-41 - PMID: 23288508 - PMCID: PMC3602406 - DOI: 10.1158/0008-5472.CAN-12-2384
Kang TH, Noh KH, Kim JH, Bae HC, Lin KY, Monie A, Pai SI, Hung CF, Wu TC, Kim TW Ectopic expression of X-linked lymphocyte-regulated protein pM1 renders tumor cells resistant to antitumor immunity. Cancer Res. 2010;70(8):3062-70 - PMID: 20395201 - PMCID: PMC2861497 - DOI: 10.1158/0008-5472.CAN-09-3856
Kang TH, Lee JH, Song CK, Han HD, Shin BC, Pai SI, Hung CF, Trimble C, Lim JS, Kim TW, Wu TC Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination. Cancer Res. 2007;67(2):802-11 - PMID: 17234792 - PMCID: PMC3181129 - DOI: 10.1158/0008-5472.CAN-06-2638
Pai SI, Wu GS, Ozören N, Wu L, Jen J, Sidransky D, El-Deiry WS Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 1998;58(16):3513-8 - PMID: 9721851
Choy E, Yelensky R, Bonakdar S, Plenge RM, Saxena R, De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C, Rivas M, Dermitzakis ET, Cahir-McFarland E, Kieff E, Hafler D, Daly MJ, Altshuler D Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines PLoS Genet. 2008;4(11):e1000287 - PMID: 19043577 - PMCID: PMC2583954 - DOI: 10.1371/journal.pgen.1000287
Ku M, Koche R, Rheinbay E, Mendenhall E, Endoh M, Mikkelsen T, Presser A, Nusbaum C, Xie X, Chi A, Adli M, Kasif S, Ptaszek L, Cowan C, Lander E, Koseki H, Bernstein B Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet. 2008;4(10):e1000242 - PMID: 18974828 - PMCID: PMC2567431 - DOI: 10.1371/journal.pgen.1000242
Mendenhall EM, Koche RP, Truong T, Zhou VW, Issac B, Chi AS, Ku M, Bernstein BE GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells. PLoS Genet. 2010;6(12):e1001244 - PMID: 21170310 - PMCID: PMC3000368 - DOI: 10.1371/journal.pgen.1001244
Ziller MJ, Müller F, Liao J, Zhang Y, Gu H, Bock C, Boyle P, Epstein CB, Bernstein BE, Lengauer T, Gnirke A, Meissner A Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types. PLoS Genet. 2011;7(12):e1002389 - PMID: 22174693 - PMCID: PMC3234221 - DOI: 10.1371/journal.pgen.1002389
Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA, Vidal M, Bernstein BE, Koseki H Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity. PLoS Genet. 2012;8(7):e1002774 - PMID: 22844243 - PMCID: PMC3405999 - DOI: 10.1371/journal.pgen.1002774
Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L Gut microbiome and anticancer immune response: really hot Sh*t! Cell Death Differ. 2014;22(2):199-214 - PMID: 24832470 - PMCID: PMC4291500 - DOI: 10.1038/cdd.2014.56
Shtatland T, Gill S, Javornik B, Johansson H, Singer B, Uhlenbeck O, Zichi D, Gold L Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. Nucleic Acids Res. 2000;28:E93 - PMID: 11058143 - PMCID: PMC113162 - DOI: 10.1093/nar/28.21.e93
Singer B, Shtatland T, Brown D, Gold L Libraries for genomic SELEX. Nucleic Acids Res. 1997;25:781-6 - PMID: 9016629 - PMCID: PMC146522 - DOI: 10.1093/nar/25.4.781
Abrams E, Shtatland T, Lerman L PCR assay for a polymorphic TaqI site in the human K-ras-2 gene on chromosome 12p (KRAS2). Nucleic Acids Res. 1991;19:4795 - PMID: 1679926 - PMCID: PMC328755 - DOI: 10.1093/nar/19.17.4795
Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites. Nucleic Acids Res. 2013;41(19):e181 - PMID: 23945932 - PMCID: PMC3799455 - DOI: 10.1093/nar/gkt716
Babitt JL, Lin HY The molecular pathogenesis of hereditary hemochromatosis. Semin Liver Dis. 2011;31(3):280-92 - PMID: 21901658 - DOI: 10.1055/s-0031-1286059
Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber M, Romero P, Wurdinger T, Xavier RJ, Geissmann F, Meylan E, Nahrendorf M, Swirski FK, Baltimore D, Weissleder R, Pittet MJ Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb Cell Rep. 2012;1(4):1-8 - PMID: 22545247 - PMCID: PMC3334310 - DOI: 10.1016/j.celrep.2012.02.009
Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure. Cell Rep. 2012;2(1):52-61 - PMID: 22840396 - PMCID: PMC3627357 - DOI: 10.1016/j.celrep.2012.06.002
Mak AB, Nixon AM, Kittanakom S, Stewart JM, Chen GI, Curak J, Gingras AC, Mazitschek R, Neel BG, Stagljar I, Moffat J Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation. Cell Rep. 2012;2(4):951-63 - PMID: 23084749 - PMCID: PMC3590846 - DOI: 10.1016/j.celrep.2012.09.016
Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma. Cell Rep. 2013;3(5):1567-1579 - PMID: 23707066 - PMCID: PMC3774301 - DOI: 10.1016/j.celrep.2013.04.021
Lan YY, Londoño D, Bouley R, Rooney MS, Hacohen N Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy. Cell Rep. 2014;9(1):180-92 - PMID: 25284779 - PMCID: PMC4555847 - DOI: 10.1016/j.celrep.2014.08.074
Levy O, Mortensen LJ, Boquet G, Tong Z, Perrault C, Benhamou B, Zhang J, Stratton T, Han E, Safaee H, Musabeyezu J, Yang Z, Multon MC, Rothblatt J, Deleuze JF, Lin CP, Karp JM A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells. Cell Rep. 2015;10(8):1261-1268 - PMID: 25732817 - PMCID: PMC4361231 - DOI: 10.1016/j.celrep.2015.01.057
Pittet M, Swirski F, Reynolds F, Josephson L, Weissleder R. Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles Nat Protoc. 2006;1(1):73-79 - PMID: 17406214 - DOI: 10.1038/nprot.2006.11
Lo Celso C, Lin CP, Scadden DT In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow. Nat Protoc. 2010;6(1):1-14 - PMID: 21212779 - PMCID: PMC3382040 - DOI: 10.1038/nprot.2010.168
Adli M, Bernstein BE Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq. Nat Protoc. 2011;6(10):1656-68 - PMID: 21959244 - PMCID: PMC4493313 - DOI: 10.1038/nprot.2011.402
Vinegoni C, Aguirre AD, Lee S, Weissleder R Imaging the beating heart in the mouse using intravital microscopy techniques. Nat Protoc. 2015;10(11):1802-1819 - PMID: 26492138 - PMCID: PMC5380003 - DOI: 10.1038/nprot.2015.119
Bremer C, Mustafa M, Bogdanov A Jr, Ntziachristos V, Petrovsky A, Weissleder R Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice Radiology. 2003;226:214-20 - PMID: 12511693 - DOI: 10.1148/radiol.2261012140
Mahmood U, Tung CH, Tang Y, Weissleder R Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice Radiology. 2002;224:446-51 - PMID: 12147841 - DOI: 10.1148/radiol.2242011589
Bremer C, Tung CH, Bogdanov A Jr, Weissleder R Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes Radiology. 2002;222:814-8 - PMID: 11867806 - DOI: 10.1148/radiol.2223010812
Weissleder R, Mahmood U Molecular imaging Radiology. 2001;219:316-33 - PMID: 11323453 - DOI: 10.1148/radiology.219.2.r01ma19316
Moore A, Josephson L, Bhorade RM, Basilion JP, Weissleder R Human transferrin receptor gene as a marker gene for MR imaging Radiology. 2001;221:244-50 - PMID: 11568347 - DOI: 10.1148/radiol.2211001784
Bremer C, Bredow S, Mahmood U, Weissleder R, Tung CH Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model Radiology. 2001;221:523-9 - PMID: 11687699 - DOI: 10.1148/radiol.2212010368
Moore A, Marecos E, Bogdanov A Jr, Weissleder R Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model Radiology. 2000;214:568-74 - PMID: 10671613 - DOI: 10.1148/radiology.214.2.r00fe19568
Weissleder R Molecular imaging: exploring the next frontier Radiology. 1999;212:609-14 - PMID: 10478223 - DOI: 10.1148/radiology.212.3.r99se18609
Mahmood U, Tung CH, Bogdanov A Jr, Weissleder R Near-infrared optical imaging of protease activity for tumor detection Radiology. 1999;213:866-70 - PMID: 10580968 - DOI: 10.1148/radiology.213.3.r99dc14866
Funovics MA, Weissleder R, Mahmood U Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 2004;231(3):659-66 - PMID: 15163807 - DOI: 10.1148/radiol.2313030831
Mahmood U Can MR Imaging Be Used to Track Delivery of Intravascularly Administered Stem Cells? Radiology. 2004;233(3):625-6 - PMID: 15564396 - DOI: 10.1148/radiol.2333041190
Chen JW, Querol Sans M, Bogdanov Jr A, Weissleder R Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates Radiology. 2006;240 (2):473-81 - PMID: 16864673 - DOI: 10.1148/radiol.2402050994
Mahmood U Can a clinically used chemoembolization vehicle improve transgene delivery? Radiology. 2006;240(3):619-20 - PMID: 16926318 - DOI: 10.1148/radiol.2403060761
Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by using Real-time Bioluminescent Imaging. Radiology. 2006;241(3):822-830 - PMID: 17114629 - DOI: 10.1148/radiol.2413050466
Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R. Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007;242 (3):751-758 - PMID: 17325064 - DOI: 10.1148/radiol.2423052065
Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U Colonic Adenocarcinomas: Near-Infrared Microcatheter Imaging of Smart Probes for Early Detection. Radiology. 2007;244(1):232-8 - PMID: 17507718 - DOI: 10.1148/radiol.2441052114
Upadhyay R, Sheth RA, Weissleder R, Mahmood U Quantitative Real-time Catheter-based Fluorescence Molecular Imaging in Mice. Radiology. 2007;245(2):523-31 - PMID: 17940307 - DOI: 10.1148/radiol.2452061613
Nahrendorf M, Hiller K, Theisen D, Hu K, Waller C, Kaiser R, Haase A, Ertl G, Brinkmann R, Bauer W Effect of transmyocardial laser revascularization on myocardial perfusion and left ventricular remodeling after myocardial infarction in rats. Radiology. 2002;225(2):487-93 - PMID: 12409584 - DOI: 10.1148/radiol.2252011325
Goldberg M, Gazelle G, Boland G, Hahn P, Mayo-Smith W, Pivovarov M, Halpern E, Wittenberg J Focal hepatic lesions: effect of three-dimensional wavelet compression on detection at CT. Radiology. 1997;202:159-65 - PMID: 8988206 - DOI: 10.1148/radiology.202.1.8988206
Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U Human Breast Cancer Tumor Models: Molecular Imaging of Drug Susceptibility and Dosing during HER2/neu-targeted Therapy. Radiology. 2008;248(3):925-35 - PMID: 18647846 - PMCID: PMC2798096 - DOI: 10.1148/radiol.2482071496
Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schar M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M Off-Resonance Angiography: A New Method to Depict Vessels--Phantom and Rabbit Studies. Radiology. 2008;249(2)::501-509 - PMID: 18780823 - PMCID: PMC2657865 - DOI: 10.1148/radiol.2491071706
Sosnovik DE Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques? Radiology. 2009;251:309-10 - PMID: 19401565 - DOI: 10.1148/radiol.2512090268
Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation. Radiology. 2009;251(3):813-21 - PMID: 19474377 - PMCID: PMC2687531 - DOI: 10.1148/radiol.2513081450
Pandharipande PV, Gervais DA, Hartman RI, Harisinghani MG, Feldman AS, Mueller PR, Gazelle GS Renal Mass Biopsy to Guide Treatment Decisions for Small Incidental Renal Tumors: A Cost-effectiveness Analysis. Radiology. 2010;256(3):836-46 - PMID: 20720070 - PMCID: PMC2923731 - DOI: 10.1148/radiol.10092013
de Marco G, Bogdanov A, Marecos E, Moore A, Simonova M, Weissleder R MR imaging of gene delivery to the central nervous system with an artificial vector. Radiology. 1998;208(1):65-71 - PMID: 9646794 - DOI: 10.1148/radiology.208.1.9646794
Weissleder R, Simonova M, Bogdanova A, Bredow S, Enochs WS, Bogdanov A MR imaging and scintigraphy of gene expression through melanin induction. Radiology. 1997;204(2):425-9 - PMID: 9240530 - DOI: 10.1148/radiology.204.2.9240530
Enochs WS, Petherick P, Bogdanova A, Mohr U, Weissleder R Paramagnetic metal scavenging by melanin: MR imaging. Radiology. 1997;204(2):417-23 - PMID: 9240529 - DOI: 10.1148/radiology.204.2.9240529
Harisinghani MG, Saini S, Weissleder R, Halpern EF, Schima W, Rubin DL, Stillman AE, Sica GT, Small WC, Hahn PF Differentiation of liver hemangiomas from metastases and hepatocellular carcinoma at MR imaging enhanced with blood-pool contrast agent Code-7227. Radiology. 1997;202(3):687-91 - PMID: 9051017 - DOI: 10.1148/radiology.202.3.9051017
Harika L, Weissleder R, Poss K, Papisov MI Macromolecular intravenous contrast agent for MR lymphography: characterization and efficacy studies. Radiology. 1996;198(2):365-70 - PMID: 8596833 - DOI: 10.1148/radiology.198.2.8596833
Gupta H, Wilkinson RA, Bogdanov AA, Callahan RJ, Weissleder R Inflammation: imaging with methoxy poly(ethylene glycol)-poly-L-lysine-DTPA, a long-circulating graft copolymer. Radiology. 1995;197(3):665-9 - PMID: 7480736 - DOI: 10.1148/radiology.197.3.7480736
Zimmer C, Weissleder R, Poss K, Bogdanova A, Wright SC, Enochs WS MR imaging of phagocytosis in experimental gliomas. Radiology. 1995;197(2):533-8 - PMID: 7480707 - DOI: 10.1148/radiology.197.2.7480707
Zimmer C, Weissleder R, O'Connor D, LaPointe L, Brady TJ, Enochs WS Cerebral iron oxide distribution: in vivo mapping with MR imaging. Radiology. 1995;196(2):521-7 - PMID: 7617871 - DOI: 10.1148/radiology.196.2.7617871
Gupta H, Weissleder R, Bogdanov AA, Brady TJ Experimental gastrointestinal hemorrhage: detection with contrast-enhanced MR imaging and scintigraphy. Radiology. 1995;196(1):239-44 - PMID: 7784574 - DOI: 10.1148/radiology.196.1.7784574
Weissleder R Liver MR imaging with iron oxides: toward consensus and clinical practice. Radiology. 1994;193(3):593-5 - PMID: 7972790 - DOI: 10.1148/radiology.193.3.7972790
Reimer P, Weissleder R, Shen T, Knoefel WT, Brady TJ Pancreatic receptors: initial feasibility studies with a targeted contrast agent for MR imaging. Radiology. 1994;193(2):527-31 - PMID: 7972773 - DOI: 10.1148/radiology.193.2.7972773
van Everdingen KJ, Enochs WS, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R Determinants of in vivo MR imaging of slow axonal transport. Radiology. 1994;193(2):485-91 - PMID: 7526413 - DOI: 10.1148/radiology.193.2.7526413
Weissleder R, Heautot JF, Schaffer BK, Nossiff N, Papisov MI, Bogdanov A, Brady TJ MR lymphography: study of a high-efficiency lymphotrophic agent. Radiology. 1994;191(1):225-30 - PMID: 8134576 - DOI: 10.1148/radiology.191.1.8134576
Bogdanov AA, Weissleder R, Frank HW, Bogdanova AV, Nossif N, Schaffer BK, Tsai E, Papisov MI, Brady TJ A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology. 1993;187(3):701-6 - PMID: 8497616 - DOI: 10.1148/radiology.187.3.8497616
Reimer P, Weissleder R, Wittenberg J, Brady TJ Receptor-directed contrast agents for MR imaging: preclinical evaluation with affinity assays. Radiology. 1992;182(2):565-9 - PMID: 1732982 - DOI: 10.1148/radiology.182.2.1732982
Weissleder R, Lee AS, Khaw BA, Shen T, Brady TJ Antimyosin-labeled monocrystalline iron oxide allows detection of myocardial infarct: MR antibody imaging. Radiology. 1992;182(2):381-5 - PMID: 1732953 - DOI: 10.1148/radiology.182.2.1732953
Weissleder R, Lee AS, Fischman AJ, Reimer P, Shen T, Wilkinson R, Callahan RJ, Brady TJ Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging. Radiology. 1991;181(1):245-9 - PMID: 1887040 - DOI: 10.1148/radiology.181.1.1887040
Reimer P, Weissleder R, Brady TJ, Yeager AE, Baldwin BH, Tennant BC, Wittenberg J Experimental hepatocellular carcinoma: MR receptor imaging. Radiology. 1991;180(3):641-5 - PMID: 1871273 - DOI: 10.1148/radiology.180.3.1871273
Seneterre E, Weissleder R, Jaramillo D, Reimer P, Lee AS, Brady TJ, Wittenberg J Bone marrow: ultrasmall superparamagnetic iron oxide for MR imaging. Radiology. 1991;179(2):529-33 - PMID: 2014305 - DOI: 10.1148/radiology.179.2.2014305
Reimer P, Weissleder R, Lee AS, Buettner S, Wittenberg J, Brady TJ Asialoglycoprotein receptor function in benign liver disease: evaluation with MR imaging. Radiology. 1991;178(3):769-74 - PMID: 1994416 - DOI: 10.1148/radiology.178.3.1994416
Lee AS, Weissleder R, Brady TJ, Wittenberg J Lymph nodes: microstructural anatomy at MR imaging. Radiology. 1991;178(2):519-22 - PMID: 1987619 - DOI: 10.1148/radiology.178.2.1987619
Reimer P, Weissleder R, Lee AS, Wittenberg J, Brady TJ Receptor imaging: application to MR imaging of liver cancer. Radiology. 1990;177(3):729-34 - PMID: 2243978 - DOI: 10.1148/radiology.177.3.2243978
Hahn PF, Stark DD, Lewis JM, Saini S, Elizondo G, Weissleder R, Fretz CJ, Ferrucci JT First clinical trial of a new superparamagnetic iron oxide for use as an oral gastrointestinal contrast agent in MR imaging. Radiology. 1990;175(3):695-700 - PMID: 2343116 - DOI: 10.1148/radiology.175.3.2343116
Weissleder R, Elizondo G, Wittenberg J, Lee AS, Josephson L, Brady TJ Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology. 1990;175(2):494-8 - PMID: 2326475 - DOI: 10.1148/radiology.175.2.2326475
Weissleder R, Elizondo G, Wittenberg J, Rabito CA, Bengele HH, Josephson L Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging. Radiology. 1990;175(2):489-93 - PMID: 2326474 - DOI: 10.1148/radiology.175.2.2326474
Elizondo G, Weissleder R, Stark DD, Guerra J, Garza J, Fretz CJ, Todd LE, Ferrucci JT Hepatic cirrhosis and hepatitis: MR imaging enhanced with superparamagnetic iron oxide. Radiology. 1990;174(3 Pt 1):797-801 - PMID: 2305063 - DOI: 10.1148/radiology.174.3.2305063
Hahn PF, Stark DD, Weissleder R, Elizondo G, Saini S, Ferrucci JT Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology. 1990;174(2):361-6 - PMID: 2296646 - DOI: 10.1148/radiology.174.2.2296646
Fretz CJ, Elizondo G, Weissleder R, Hahn PF, Stark DD, Ferrucci JT Superparamagnetic iron oxide-enhanced MR imaging: pulse sequence optimization for detection of liver cancer. Radiology. 1989;172(2):393-7 - PMID: 2748820 - DOI: 10.1148/radiology.172.2.2748820
Weissleder R, Thrall JH The lymphatic system: diagnostic imaging studies. Radiology. 1989;172(2):315-7 - PMID: 2748809 - DOI: 10.1148/radiology.172.2.2748809
Weissleder R, Elizondo G, Josephson L, Compton CC, Fretz CJ, Stark DD, Ferrucci JT Experimental lymph node metastases: enhanced detection with MR lymphography. Radiology. 1989;171(3):835-9 - PMID: 2717761 - DOI: 10.1148/radiology.171.3.2717761
Dousset M, Weissleder R, Hendrick RE, Stark DD, Fretz CJ, Elizondo G, Hahn PF, Saini S, Ferrucci JT Short TI inversion-recovery imaging of the liver: pulse-sequence optimization and comparison with spin-echo imaging. Radiology. 1989;171(2):327-33 - PMID: 2704797 - DOI: 10.1148/radiology.171.2.2704797
Rummeny E, Weissleder R, Sironi S, Stark DD, Comptom CC, Hahn PF, Saini S, Wittenberg J, Ferrucci JT Central scars in primary liver tumors: MR features, specificity, and pathologic correlation. Radiology. 1989;171(2):323-6 - PMID: 2539605 - DOI: 10.1148/radiology.171.2.2539605
Weissleder H, Weissleder R Interstitial lymphangiography: initial clinical experience with a dimeric nonionic contrast agent. Radiology. 1989;170(2):371-4 - PMID: 2911660 - DOI: 10.1148/radiology.170.2.2911660
Weissleder R, Hahn PF, Stark DD, Elizondo G, Saini S, Todd LE, Wittenberg J, Ferrucci JT Superparamagnetic iron oxide: enhanced detection of focal splenic tumors with MR imaging. Radiology. 1988;169(2):399-403 - PMID: 3174987 - DOI: 10.1148/radiology.169.2.3174987
Stark DD, Weissleder R, Elizondo G, Hahn PF, Saini S, Todd LE, Wittenberg J, Ferrucci JT Superparamagnetic iron oxide: clinical application as a contrast agent for MR imaging of the liver. Radiology. 1988;168(2):297-301 - PMID: 3393649 - DOI: 10.1148/radiology.168.2.3393649
Weissleder H, Weissleder R Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology. 1988;167(3):729-35 - PMID: 3363131 - DOI: 10.1148/radiology.167.3.3363131
Tsang YM, Stark DD, Chen MC, Weissleder R, Wittenberg J, Ferrucci JT Hepatic micrometastases in the rat: ferrite-enhanced MR imaging. Radiology. 1988;167(1):21-4 - PMID: 3347724 - DOI: 10.1148/radiology.167.1.3347724
Weissleder R, Stark DD, Rummeny EJ, Compton CC, Ferrucci JT Splenic lymphoma: ferrite-enhanced MR imaging in rats. Radiology. 1988;166(2):423-30 - PMID: 3336717 - DOI: 10.1148/radiology.166.2.3336717
Elizondo G, Weissleder R, Stark DD, Todd LE, Compton C, Wittenberg J, Ferrucci JT Amebic liver abscess: diagnosis and treatment evaluation with MR imaging. Radiology. 1987;165(3):795-800 - PMID: 2891154 - DOI: 10.1148/radiology.165.3.2891154
Waller C, Kahler E, Hiller KH, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer WR Myocardial perfusion and intracapillary blood volume in rats at rest and with coronary dilatation: MR imaging in vivo with use of a spin-labeling technique. Radiology. 2000;215(1):189-97 - PMID: 10751486 - DOI: 10.1148/radiology.215.1.r00ap07189
Nahrendorf M, Sosnovik DE Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging? Radiology. 2011;260(2):309-10 - PMID: 21778448 - DOI: 10.1148/radiol.11111017
Su HS, Nahrendorf M, Panizzi PR, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW Vasculitis: Molecular Imaging by Targeting the Inflammatory Enzyme Myeloperoxidase. Radiology. 2011;262(1):181-90 - PMID: 22084204 - PMCID: PMC3244672 - DOI: 10.1148/radiol.11110040
Forghani R, Wojtkiewicz GR, Zhang Y, Seeburg D, Bautz BR, Pulli B, Milewski AR, Atkinson WL, Iwamoto Y, Zhang ER, Etzrodt M, Rodriguez E, Robbins CS, Swirski FK, Weissleder R, Chen JW Demyelinating Diseases: Myeloperoxidase as an Imaging Biomarker and Therapeutic Target. Radiology. 2012;263(2):451-60 - PMID: 22438365 - PMCID: PMC3329272 - DOI: 10.1148/radiol.12111593
Sosnovik DE, Nahrendorf M, Caravan P Science to Practice: How Will Myocardial Inflammation Be Imaged with MR Imaging? Radiology. 2012;264(2):309-11 - PMID: 22821689 - PMCID: PMC6939999 - DOI: 10.1148/radiol.12121094
Pulli B, Bure L, Wojtkiewicz GR, Iwamoto Y, Ali M, Li D, Schob S, Li-Chun Hsieh K, Jacobs AH, Chen JW Multiple Sclerosis: Myeloperoxidase Immunoradiology Improves Detection of Acute and Chronic Disease in Experimental Model. Radiology. 2014;275(2):480-9 - PMID: 25494298 - PMCID: PMC4455671 - DOI: 10.1148/radiol.14141495
Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW Myeloperoxidase Nuclear Imaging for Epileptogenesis. Radiology. 2015;278(3):822-30 - PMID: 26397127 - PMCID: PMC4770943 - DOI: 10.1148/radiol.2015141922
Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int. 2007;71(6):504-13 - PMID: 17228368 - DOI: 10.1038/sj.ki.5002041
Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD Controversies in nephrology: Response to ''renal albumin handling, facts, and artifacts'' Kidney Int. 2007;72(10):1195-7 - PMID: 17851467 - DOI: 10.1038/sj.ki.5002528
Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD Response to ''Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique'' Kidney Int. 2007;72:1411 - PMID: 18004315
Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD Response to ''On the origin of albuminuria'' Kidney Int. 2007;72:1409-10 - PMID: 18004312
Gutierrez O, Lin H Refractory hyponatremia. Kidney Int. 2007;71(1):79-82 - PMID: 16985516 - DOI: 10.1038/sj.ki.5001845
Zalyapin EA, Bouley R, Hasler U, Vilardaga JP, Lin HY, Brown D, Ausiello DA Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling. Kidney Int. 2008;74(12):1557-67 - PMID: 18813286 - PMCID: PMC3730289 - DOI: 10.1038/ki.2008.412
Miller RL, Lucero OM, Riemondy KA, Baumgartner BK, Brown D, Breton S, Nelson RD The V-ATPase B1-subunit promoter drives expression of Cre recombinase in intercalated cells of the kidney. Kidney Int. 2008;75(4):435-9 - PMID: 19052537 - PMCID: PMC4301582 - DOI: 10.1038/ki.2008.569
Miranda KC, Bond DT, McKee M, Skog J, Paunescu TG, Da Silva N, Brown D, Russo LM Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease. Kidney Int. 2010;78(2):191-9 - PMID: 20428099 - PMCID: PMC4451567 - DOI: 10.1038/ki.2010.106
Schreiner R, Frindt G, Diaz F, Carvajal-Gonzalez JM, Perez Bay AE, Palmer LG, Marshansky V, Brown D, Philp NJ, Rodriguez-Boulan E The absence of a clathrin adapter confers unique polarity essential to proximal tubule function. Kidney Int. 2010;78(4):382-8 - PMID: 20531453 - PMCID: PMC3684398 - DOI: 10.1038/ki.2010.166
Brown D, Breton S Sorting proteins to their target membranes. Kidney Int. 2000;57(3):816-24 - PMID: 10720934 - DOI: 10.1046/j.1523-1755.2000.00920.x
Bouley R Corin: a key protein of an adaptive renal mechanism to respond to salt variation? Kidney Int. 2012;82(1):7-8 - PMID: 22699378 - DOI: 10.1038/ki.2012.123
Huang J, McKee M, Huang HD, Xiang A, Davidson AJ, Lu HA A zebrafish model of conditional targeted podocyte ablation and regeneration. Kidney Int. 2013;83(6):1193-200 - PMID: 23466998 - PMCID: PMC3672345 - DOI: 10.1038/ki.2013.6
Moore A, Bonner-Weir S, Weissleder R Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes Diabetes. 2001;50:2231-6 - PMID: 11574403 - DOI: 10.2337/diabetes.50.10.2231
Russo LM, del Re E, Brown D, Lin HY Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor. Diabetes. 2007;56(2):380-8 - PMID: 17259382 - DOI: 10.2337/db06-1018
Cruz DN, Perazella MA, Bellomo R, de Cal M, Polanco N, Corradi V, Lentini P, Nalesso F, Ueno T, Ranieri VM, Ronco C Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review. Crit Care. 2008;11(2):R47 - PMID: 17448226 - PMCID: PMC2206475 - DOI: 10.1186/cc5780
McCarthy J, Jaffer F, Weissleder R. A Macrophage Targeted Theranostic Nanoparticle for Biomedical Applications Small. 2006;2(8-9):983-987 - PMID: 17193154 - DOI: 10.1002/smll.200600139
Sun EY, Weissleder R, Josephson L. Continuous Analyte Sensing with Magnetic Nanoswitches Small. 2006;(2) 10:1144-1147 - PMID: 17193579 - DOI: 10.1002/smll.200600204
McCarthy JR, Korngold E, Weissleder R, Jaffer FA A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis. Small. 2010;6(18):2041-9 - PMID: 20721949 - PMCID: PMC3018665 - DOI: 10.1002/smll.201000596
Agasti SS, Kohler RH, Liong M, Peterson VM, Lee H, Weissleder R Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking. Small. 2012;9(2):222-7 - PMID: 22996932 - PMCID: PMC3552149 - DOI: 10.1002/smll.201201007
Liu R, Rallo R, Weissleder R, Tassa C, Shaw S, Cohen Y Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries. Small. 2013;9(9-10):1842-52 - PMID: 23423856 - DOI: 10.1002/smll.201201903
Im H, Oh SH Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges. Small. 2013;10(4):680-4 - PMID: 24123889 - DOI: 10.1002/smll.201301475
Koo H, Choi M, Kim E, Hahn SK, Weissleder R, Yun SH Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small. 2015;11(48):6458-66 - PMID: 26768353 - PMCID: PMC5556392 - DOI: 10.1002/smll.201502972
Im H, Oh SH Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges. Small. 2013;10(4):680-4 - PMID: 24123889 - DOI: 10.1002/smll.201301475
Hennings JC, Picard N, Huebner AK, Stauber T, Maier H, Brown D, Jentsch TJ, Vargas-Poussou R, Eladari D, Hübner CA A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule. EMBO Mol Med. 2012;4(10):1057-71 - PMID: 22933323 - PMCID: PMC3491836 - DOI: 10.1002/emmm.201201527
Hingtgen SD, Kasmieh R, van de Water J, Weissleder R, Shah K Determining Multiple Aspects of Stem Cell-Based Therapies Using Novel Diagnostic and Therapeutic Multifunctional Molecules. Stem Cells. 2010;28(4):832-41 - PMID: 20127797 - PMCID: PMC3021283 - DOI: 10.1002/stem.313
Teo GS, Yang Z, Carman CV, Karp JM, Lin CP Intravital Imaging of Mesenchymal Stem Cell Trafficking and Association with Platelets and Neutrophils. Stem Cells. 2015;33(1):265-277 - PMID: 25263183 - PMCID: PMC4270897 - DOI: 10.1002/stem.1848
Hewett J, Nery F, Niland B, Ge P, Tan P, Hadwiger P, Tannous B, Sah D, Breakefield X siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells. Hum Mol Genet. 2008;17:1436-45 - PMID: 18258738 - PMCID: PMC2861568 - DOI: 10.1093/hmg/ddn032
Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, Macdonald ME, Seong IS Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis. Hum Mol Genet. 2011;20(12):2344-55 - PMID: 21447599 - PMCID: PMC3098733 - DOI: 10.1093/hmg/ddr127
Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H Impaired Hepcidin Expression in Alpha-1-Antitrypsin Deficiency Associated with Iron Overload and Progressive Liver Disease. Hum Mol Genet. 2015;24(21):6254-63 - PMID: 26310624 - PMCID: PMC4599680 - DOI: 10.1093/hmg/ddv348
Pulli B, Ali M, Iwamoto Y, Zeller MW, Schob S, Linnoila JJ, Chen JW Myeloperoxidase - Hepatocyte - Stellate Cell Crosstalk Promotes Hepatocyte Injury and Fibrosis in Experimental NASH. Antioxid Redox Signal. 2015;23(16):1255-1269 - PMID: 26058518 - PMCID: PMC4677570 - DOI: 10.1089/ars.2014.6108
Lauriol J, Keith K, Jaffré F, Couvillon A, Saci A, Goonasekera SA, McCarthy JR, Kessinger CW, Wang J, Ke Q, Kang PM, Molkentin JD, Carpenter C, Kontaridis MI RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis. Sci Signal. 2014;7(348):ra100 - PMID: 25336613 - PMCID: PMC4300109 - DOI: 10.1126/scisignal.2005262
Meyer AS, Miller MA, Gertler FB, Lauffenburger DA The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells. Sci Signal. 2013;6(287):ra66 - PMID: 23921085 - PMCID: PMC3947921 - DOI: 10.1126/scisignal.2004155
McCarthy J, Kelly KA, Sun EY, Weissleder R. Targeted delivery of multifunctional magnetic nanoparticles Nanomedicine. 2007;2(2):153-167 - PMID: 17716118 - DOI: 10.2217/17435889.2.2.153
Martinez-Boubeta C, Balcells L, Cristool R, Sanfeliu C, Rodriguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martinez B Self-assembled Multifunctional Fe/MgO Nanospheres for Magnetic Resonance Imaging and Hyperthermia. Nanomedicine. 2009;6(2):362-370 - PMID: 19800988 - DOI: 10.1016/j.nano.2009.09.003
McCarthy JR The future of theranostic nanoagents. Nanomedicine. 2009;4(7):693-5 - PMID: 19839803 - DOI: 10.2217/nnm.09.58
Ghazani A, Pectasides M, Sharma A, Castro CM, Mino-Kenudson M, Lee H, Shepard JA, Weissleder R Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance. Nanomedicine. 2013;10 :661-668 - PMID: 24200523 - PMCID: PMC3966960 - DOI: 10.1016/j.nano.2013.10.008
Engelmayr G, Rabkin E, Sutherland F, Schoen F, Mayer J, Sacks M The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue. Biomaterials . 2005;26:175-87 - PMID: 15207464 - DOI: 10.1016/j.biomaterials.2004.02.035
Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells. Biomaterials . 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971 - DOI: 10.1016/j.biomaterials.2009.10.019
Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction. Biomaterials . 2010;32(4):1102-9 - PMID: 21035182 - PMCID: PMC6805145 - DOI: 10.1016/j.biomaterials.2010.10.005
Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics. Biomaterials . 2012;33(20):5004-12 - PMID: 22494889 - PMCID: PMC3366278 - DOI: 10.1016/j.biomaterials.2012.03.065
Desai RM, Koshy ST, Hilderbrand SA, Mooney DJ, Joshi NS Versatile click alginate hydrogels crosslinked via tetrazine-norbornene chemistry. Biomaterials . 2015;50:30-7 - PMID: 25736493 - DOI: 10.1016/j.biomaterials.2015.01.048
Courties G, Moskowitz MA, Nahrendorf M The Innate Immune System After Ischemic Injury: Lessons to Be Learned From the Heart and Brain. JAMA Neurol. 2014;71(2):233-6 - PMID: 24296962 - PMCID: PMC3946050 - DOI: 10.1001/jamaneurol.2013.5026
Sosnovik DE, Weissleder R Emerging concepts in molecular MRI. Curr Opin Biotech. 2007;18(1):4-10 - PMID: 17126545 - DOI: 10.1016/j.copbio.2006.11.001
Wunder A, Tung CH, Muller-Ladner U, Weissleder R, Mahmood U In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arth Rheum/AR C Res. 2004;50(8):2459-65 - PMID: 15334458 - DOI: 10.1002/art.20379
Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arth Rheum/AR C Res. 2007;56(1):117-128 - PMID: 17195214 - DOI: 10.1002/art.22303
Mendenhall E, Bernstein B Chromatin state maps: new technologies, new insights. Curr Opin Genet Dev. 2008;18(2):109-15 - PMID: 18339538 - PMCID: PMC2486450 - DOI: 10.1016/j.gde.2008.01.010
Khazaie K, von Boehmer H The impact of CD4(+)CD25(+) Treg on tumor specific CD8(+) T cell cytotoxicity and cancer. Semin Cancer Biol. 2006;16(2):124-136 - PMID: 16443370 - DOI: 10.1016/j.semcancer.2005.11.006
Speiser D, Pittet M, Rimoldi D, Guillaume P, Luescher I, Lienard D, Lejeune F, Cerottini J, Romero P Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. Semin Cancer Biol. 2003;13:461-72 - PMID: 15001165 - DOI: 10.1016/j.semcancer.2003.09.010
Shah K, Tang Y, Breakefield X, Weissleder R Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo Oncogene. 2003;22:6865-72 - PMID: 14534533 - DOI: 10.1038/sj.onc.1206748
van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene. 2010;29(22):3185-95 - PMID: 20305695 - PMCID: PMC3390229 - DOI: 10.1038/onc.2010.75
Aranda F, Bloy N, Pesquet J, Petit B, Chaba K, Sauvat A, Kepp O, Khadra N, Enot D, Pfirschke C, Pittet M, Zitvogel L, Kroemer G, Senovilla L Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer. Oncogene. 2014;34(23):3053-62 - PMID: 25065595 - DOI: 10.1038/onc.2014.234
Helman E, Naxerova K, Kohane IS DNA hypermethylation in lung cancer is targeted at differentiation-associated genes. Oncogene. 2011;31(9):1181-8 - PMID: 21804601 - DOI: 10.1038/onc.2011.307
Trink B, Pai SI, Spunt SL, Raman V, Cairns P, Jen J, Gabrielson E, Sukumar S, Sidransky D Absence of TSG101 transcript abnormalities in human cancers. Oncogene. 1998;16(21):2815-8 - PMID: 9652749 - DOI: 10.1038/sj.onc.1201795
Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Mol Ther Nucleic Acids. 2012;1:e4 - PMID: 23344621 - PMCID: PMC3381593 - DOI: 10.1038/mtna.2011.3
Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO. Codon-optimized gaussia luciferase cDNA for Mammalian gene expression in culture and in vivo Mol Ther. 2005;11(3):435-43 - PMID: 15727940 - DOI: 10.1016/j.ymthe.2004.10.016
Shah K, Tung CH, Breakefield X, Weissleder R. In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis Mol Ther. 2005;11 (6):926-931 - PMID: 15922963 - DOI: 10.1016/j.ymthe.2005.01.017
Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging. Mol Ther. 2006;4(6):779-88 - PMID: 16996314 - PMCID: PMC2819149 - DOI: 10.1016/j.ymthe.2006.08.008
Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma. Mol Ther. 2010;18(6):1130-42 - PMID: 20179672 - PMCID: PMC2889737 - DOI: 10.1038/mt.2010.29
Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL Bevacizumab With Angiostatin-armed oHSV Increases Antiangiogenesis and Decreases Bevacizumab-induced Invasion in U87 Glioma. Mol Ther. 2011;20(1):37-45 - PMID: 21915104 - PMCID: PMC3255598 - DOI: 10.1038/mt.2011.187
Noh KH, Kang TH, Kim JH, Pai SI, Lin KY, Hung CF, Wu TC, Kim TW Activation of Akt as a mechanism for tumor immune evasion. Mol Ther. 2008;17(3):439-47 - PMID: 19107122 - PMCID: PMC2835083 - DOI: 10.1038/mt.2008.255
Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R. Mapping of nodal disease in locally advanced prostate cancer: Rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy Int J Radiat Oncol Biol Phys. 2005;63(4):1262-9 - PMID: 16253781 - DOI: 10.1016/j.ijrobp.2005.07.952
Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009;74(4):1207-16 - PMID: 19545786 - PMCID: PMC2733223 - DOI: 10.1016/j.ijrobp.2009.02.052
Macdonald SM, Harisinghani MG, Katkar A, Napolitano B, Wolfgang J, Taghian AG Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer. Int J Radiat Oncol Biol Phys. 2009;77(4):1098-104 - PMID: 19836160 - DOI: 10.1016/j.ijrobp.2009.06.002
Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T Imaging Primary Lung Cancers in Mice to Study Radiation Biology. Int J Radiat Oncol Biol Phys. 2010;76(4):973-977 - PMID: 20206017 - PMCID: PMC2847457 - DOI: 10.1016/j.ijrobp.2009.11.038
Kirsch DG, Grimm J, Guimaraes AR, Weissleder R In response to dr. Garbow and colleagues. Int J Radiat Oncol Biol Phys. 2011;79(3):959 - PMID: 21281902
Breton S, Brown D Regulation of Luminal Acidification by the V-ATPase. Physiology (Bethesda). 2013;28(5):318-29 - PMID: 23997191 - PMCID: PMC3768094 - DOI: 10.1152/physiol.00007.2013
Basilion JP, Yeon S, Botnar R Magnetic Resonance Imaging: Utility as a Molecular Imaging Modality. Curr Top Dev Biol. 2005;70(c):1-33 - PMID: 16338335 - DOI: 10.1016/S0070-2153(05)70001-6
Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud. Curr Top Dev Biol. 2010;20(22):1993-2002 - PMID: 21055947 - PMCID: PMC2998074 - DOI: 10.1016/j.cub.2010.09.063
Mahmood U, Josephson L Molecular MR Imaging Probes P IEEE. 0;93 (4):800-808
Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008;28:4406-13 - PMID: 18434519 - PMCID: PMC3021321 - DOI: 10.1523/JNEUROSCI.0296-08.2008
Samad T, Srinivasan A, Karchewski L, Jeong S, Campagna J, Ji R, Fabrizio D, Zhang Y, Lin HY, Bell E, Woolf C DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci. 2004;24(8):2027-36 - PMID: 14985445 - PMCID: PMC6730385 - DOI: 10.1523/JNEUROSCI.4115-03.2004
Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, Inquimbert P, Niederkofler V, Salie R, Sun CC, Lin HY, Arber S, Coppola G, Woolf CJ, Samad TA The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling. J Neurosci. 2011;31(50):18391-18400 - PMID: 22171041 - PMCID: PMC3243947 - DOI: 10.1523/JNEUROSCI.4550-11.2011
Paly JJ, Efstathiou JA, Hedgire SS, Chung PW, O'Malley M, Shah A, Bekelman JE, Harisinghani M, Shipley WU, Zietman AL, Beard C Mapping patterns of nodal metastases in seminoma: Rethinking radiotherapy fields. Radiother Oncol. 2013;106(1):64-8 - PMID: 23321493 - DOI: 10.1016/j.radonc.2012.12.002
Yuan Y, Andronesi OC, Bortfeld TR, Richter C, Wolf R, Guimaraes AR, Hong TS, Seco J Feasibility study of in vivo MRI based dosimetric verification of proton end-of-range for liver cancer patients. Radiother Oncol. 2013;106(3):378-82 - PMID: 23473960 - DOI: 10.1016/j.radonc.2013.01.016
Lee H, Liu Y, Ham D, Westervelt RM Integrated cell manipulation system--CMOS/microfluidic hybrid. Lab Chip. 2007;7(3):331-7 - PMID: 17330164 - DOI: 10.1039/b700373k
Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H Self-assembled magnetic filter for highly efficient immunomagnetic separation. Lab Chip. 2010;11(1):147-51 - PMID: 20949198 - PMCID: PMC3005961 - DOI: 10.1039/c0lc00149j
Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H Miniature magnetic resonance system for point-of-care diagnostics. Lab Chip. 2011;11(13):2282-7 - PMID: 21547317 - PMCID: PMC3115660 - DOI: 10.1039/c1lc20177h
Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics. Lab Chip. 2012;12(17):3103-10 - PMID: 22760641 - PMCID: PMC3411869 - DOI: 10.1039/c2lc40337d
Castro CM, Ghazani AA, Chung J, Shao H, Issadore D, Yoon TJ, Weissleder R, Lee H Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells. Lab Chip. 2013;14(1):14-23 - PMID: 23835814 - PMCID: PMC3844052 - DOI: 10.1039/c3lc50621e
Issadore D, Park YI, Shao H, Min C, Lee K, Liong M, Weissleder R*, Lee H* Magnetic sensing technology for molecular analyses. Lab Chip. 2014;14(14):2385-97 - PMID: 24887807 - PMCID: PMC4098149 - DOI: 10.1039/c4lc00314d
Ng EX, Miller MA, Jing T, Lauffenburger DA, Chen CH Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array. Lab Chip. 2015;15(4):1153-9 - PMID: 25553996 - DOI: 10.1039/c4lc01162g
Lindquist NC, Lesuffleur A, Im H, Oh SH Sub-micron resolution surface plasmon resonance imaging enabled by nanohole arrays with surrounding Bragg mirrors for enhanced sensitivity and isolation. Lab Chip. 2008;9(3):382-7 - PMID: 19156286 - DOI: 10.1039/b816735d
Gonçalves I, den Ruijter H, Nahrendorf M, Pasterkamp G Detecting the vulnerable plaque in patients. J Intern Med. 2015;278(5):520-30 - PMID: 26306911 - DOI: 10.1111/joim.12414
Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ Genetic and Clinical Correlates of Early Outgrowth Colony Forming Units. Circ Cardiovasc Genet. 2011;4(3):296-304 - PMID: 21493818 - PMCID: PMC3339257 - DOI: 10.1161/CIRCGENETICS.110.958470
McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R Targeted nanoagents for the detection of cancers. Mol Oncol. 2010;4(6):511-28 - PMID: 20851695 - PMCID: PMC2981649 - DOI: 10.1016/j.molonc.2010.08.003
Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R MRI of a Novel Murine Working Heart Transplant Model Circ Heart Fail. 2009;2:272-274 - PMID: 19718275 - PMCID: PMC2733535 - DOI: 10.1161/CIRCHEARTFAILURE.109.852707
He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Brandt M, Hilgendorf I, Sun Y, Ye YX, Iwamoto Y, Tricot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages. Circ Heart Fail. 2015;8(5):980-7 - PMID: 26232205 - PMCID: PMC4568849 - DOI: 10.1161/CIRCHEARTFAILURE.115.002334
Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP Association Between Reduced Plasma 25-hydroxy Vitamin D and Increased Risk of Cancer in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2013;12(5):821-7 - PMID: 24161349 - PMCID: PMC3995841 - DOI: 10.1016/j.cgh.2013.10.011
Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP Serum Inflammatory Markers and Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2014;12(8):1342-1348.e1 - PMID: 24407106 - PMCID: PMC4085150 - DOI: 10.1016/j.cgh.2013.12.030
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014;12(11):1905-1910 - PMID: 24632349 - PMCID: PMC4162859 - DOI: 10.1016/j.cgh.2014.02.034
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP Colonoscopy is Associated with a Reduced Risk for Colon Cancer and Mortality in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2014;13(2):322-329.e1 - PMID: 25041865 - PMCID: PMC4297589 - DOI: 10.1016/j.cgh.2014.07.018
Jaffer FA, Tung CH, Gerszten RE, Weissleder R In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe Arterioscler Thromb Vasc Biol. 2002;22:1929-35 - PMID: 12426227 - DOI: 10.1161/01.atv.0000033089.56970.2d
Simoncini T, Rabkin E, Liao J Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells. Arterioscler Thromb Vasc Biol. 2003;23:198-203 - PMID: 12588759 - DOI: 10.1161/01.atv.0000053846.71621.93
Jaffer FA, Libby P, Weissleder R Optical and Multimodality Molecular Imaging. Insights Into Atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29(7):1017-24 - PMID: 19359659 - PMCID: PMC2733228 - DOI: 10.1161/ATVBAHA.108.165530
Swirski FK, Weissleder R, Pittet MJ Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29(10):1424-32 - PMID: 19372462 - PMCID: PMC2746262 - DOI: 10.1161/ATVBAHA.108.180521
Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors. Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251 - DOI: 10.1161/ATVBAHA.109.193086
Deguchi JO, Yamazaki H, Aikawa E, Aikawa M Chronic Hypoxia Activates the Akt and {beta}-Catenin Pathways in Human Macrophages. Arterioscler Thromb Vasc Biol. 2009;29(10):1664-70 - PMID: 19644051 - DOI: 10.1161/ATVBAHA.109.194043
Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis. Novel Detection by Dual-Target Fluorescence Molecular Imaging. Arterioscler Thromb Vasc Biol. 2010;30(10):1933-9 - PMID: 20689078 - PMCID: PMC3030475 - DOI: 10.1161/ATVBAHA.110.206342
Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography-Computed Tomography. Arterioscler Thromb Vasc Biol. 2011;31(4):750-7 - PMID: 21252070 - PMCID: PMC3060293 - DOI: 10.1161/ATVBAHA.110.221499
Swirski FK The spatial and developmental relationships in the macrophage family. Arterioscler Thromb Vasc Biol. 2011;31(7):1517-22 - PMID: 21677294 - PMCID: PMC3117206 - DOI: 10.1161/ATVBAHA.110.221150
Ripplinger CM, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA Inflammation Modulates Murine Venous Thrombosis Resolution In Vivo: Assessment by Multimodal Fluorescence Molecular Imaging. Arterioscler Thromb Vasc Biol. 2012;32(11):2616-24 - PMID: 22995524 - PMCID: PMC3516622 - DOI: 10.1161/ATVBAHA.112.251983
Hilgendorf I, Swirski FK, Robbins CS Monocyte Fate in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2014;35(2):272-9 - PMID: 25538208 - DOI: 10.1161/ATVBAHA.114.303565
Dutta P, Nahrendorf M Monocytes in Myocardial Infarction. Arterioscler Thromb Vasc Biol. 2015;35(5):1066-70 - PMID: 25792449 - PMCID: PMC4409536 - DOI: 10.1161/ATVBAHA.114.304652
Libby P, King K Biomarkers: A Challenging Conundrum in Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2015;35(12):2491-5 - PMID: 26543097 - DOI: 10.1161/ATVBAHA.115.305233
Querol M, Chen JW, Weissleder R, Bogdanov A Jr. DTPA-bisamide-Based MR Sensor Agents for Peroxidase Imaging Org Lett. 2005;7(9):1719-22 - PMID: 15844889 - DOI: 10.1021/ol050208v
Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA A Highly Selective Fluorescent Probe for Thiol Bioimaging. Org Lett. 2007;10 :37-40 - PMID: 18062694 - DOI: 10.1021/ol702539v
McCarthy JR, Jenkins HA, Bruckner C Free base meso-tetraaryl-morpholinochlorins and porpholactone from meso-tetraaryl-2,3-dihydroxy-chlorin. Org Lett. 2003;5(1):19-22
Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R A Concise Silylamine Approach to 2-Amino-3-hydroxy-indoles with Potent in vivo Antimalaria Activity. Org Lett. 2010;12(18):3998-4001 - PMID: 20718474 - PMCID: PMC7479540 - DOI: 10.1021/ol101566h
Castro CM, Im H, Le C, Lee H, Weissleder R, Birrer MJ Exploring alternative ovarian cancer biomarkers using innovative nanotechnology strategies. Cancer Metastasis Rev. 2015;34(1):75-82 - PMID: 25543192 - PMCID: PMC5474936 - DOI: 10.1007/s10555-014-9546-9
Tong T, Yang Z, Chen JW, Zhu J, Yao Z Dynamic 1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma. Oncotarget. 2015;6(31):32257-32265 - PMID: 26337080 - PMCID: PMC4741675 - DOI: 10.18632/oncotarget.4899
Nahrendorf M, Dutta P Targeting splenic hematopoietic stem cells in cardiovascular disease. Oncotarget. 2015;6(24):19918-9 - PMID: 26343366 - PMCID: PMC4652955 - DOI: 10.18632/oncotarget.4918
Hilderbrand S, Weissleder R. Optimized pH-responsive cyanine fluorochromes for detection of acidic environments Chem Commun. 2007;(26):2747-9 - PMID: 17594041 - DOI: 10.1039/b703764c
Kim YM, Hilderbrand S, Weissleder R, Tung CH Sugar sensing based on induced pH changes Chem Commun. 2007;(22):2299-2301 - PMID: 17534523 - DOI: 10.1039/b700741h
McCarthy JR, Hyland MA, Bruckner C Indaphyrin, a meso-tetraphenylsecochlorin-derived chromophore incorporating o-phenyl-to-β-linkages Chem Commun. 2003;:1738-9
Garanger E, Aikawa E, Reynolds F, Weissleder R, Josephson L Simplified syntheses of complex multifunctional nanomaterials. Chem Commun. 2008;39:4792-4 - PMID: 18830495 - PMCID: PMC2692914 - DOI: 10.1039/b809537j
Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun. 2009;28:4188-90 - PMID: 19585016 - PMCID: PMC2748243 - DOI: 10.1039/b905927j
Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L A DNA-binding Gd chelate for the detection of cell death by MRI. Chem Commun. 2009;(29):4444-6 - PMID: 19597620 - PMCID: PMC2754278 - DOI: 10.1039/b907375b
Agasti SS, Laughney AM, Kohler RH, Weissleder R A photoactivatable drug–caged fluorophore conjugate allows direct quantification of intracellular drug transport Chem Commun. 2013;49(94):11050-2 - PMID: 24135896 - PMCID: PMC3856557 - DOI: 10.1039/c3cc46089d
Kim E, Yang KS, Giedt RJ, Weissleder R Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chem Commun. 2014;50(34):4504-7 - PMID: 24663433 - PMCID: PMC4028821 - DOI: 10.1039/c4cc00144c
McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy. Neuroimage. 2008;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022
Hyde D, de Kleine R, MacLaurin S, Miller E, Brooks D, Krucker T, Ntziachristos V Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model. Neuroimage. 2009;44(4):1304-11 - PMID: 19041402 - DOI: 10.1016/j.neuroimage.2008.10.038
Yuan H, Luo J, Weissleder R, Cantley L, Josephson L Wortmannin-C20 Conjugates Generate Wortmannin. J Med Chem. 2006;49(2):740-747 - PMID: 16420059 - DOI: 10.1021/jm050699p
Galande A, Hilderbrand S, Weissleder R, Tung CH. Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core J Med Chem. 2006;49(15):4715-20 - PMID: 16854078 - DOI: 10.1021/jm051001a
Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L. Multivalent effects of RGD peptides obtained by nanoparticle display J Med Chem. 2006;49(20):6087-6093
Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L Slow Self-Activation Enhances The Potency of Viridin Prodrugs. J Med Chem. 2008;51(15):4699-707 - PMID: 18630894 - PMCID: PMC2663427 - DOI: 10.1021/jm800374f
Estiu G, Greenberg E, Harrison C, Kwiatkowski N, Mazitschek R, Bradner J, Wiest O Structural origin of selectivity in class II-selective histone deacetylase inhibitors. J Med Chem. 2008;51:2898-906 - PMID: 18412327 - DOI: 10.1021/jm7015254
Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum. J Med Chem. 2009;52(8):2185-7 - PMID: 19317450 - PMCID: PMC2669731 - DOI: 10.1021/jm801654y
Hendricks JA, Keliher EJ, Marinelli B, Reiner T, Weissleder R, Mazitschek R In Vivo PET-imaging of Histone Deacetylases by 18F-Suberoylanilide Hydroxamic Acid (18F-SAHA). J Med Chem. 2011;54(15):5576-82 - PMID: 21721525 - PMCID: PMC3150598 - DOI: 10.1021/jm200620f
Kissau L, Stahl P, Mazitschek R, Giannis A, Waldmann H Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold. J Med Chem. 2003;46(14):2917-31 - PMID: 12825933 - DOI: 10.1021/jm0307943
Lewin M, Bredow S, Sergeyev N, Marecos E, Bogdanov A Jr, Weissleder R In vivo assessment of vascular endothelial growth factor-induced angiogenesis Int J Cancer. 1999;83:798-802 - PMID: 10597197 - DOI: 10.1002/(sici)1097-0215(19991210)83:6<798::aid-ijc16>3.0.co;2-w
Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U. A novel mouse model for segmental orthotopic colon cancer Int J Cancer. 2005;117(3):335-9 - PMID: 15900588 - DOI: 10.1002/ijc.21185
Figueiredo JL, Alencar H, Weissleder R, Mahmood U Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006;118(11):2672-7 - PMID: 16380983 - DOI: 10.1002/ijc.21713
Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007;(121) 11:2492-2500 - PMID: 17683072 - DOI: 10.1002/ijc.22995
Kirkin V, Thiele W, Baumann P, Mazitschek R, Rohde K, Fellbrich G, Weich H, Waltenberger J, Giannis A, Sleeman JP MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo. Int J Cancer. 2004;112(6):986-93 - PMID: 15386354 - DOI: 10.1002/ijc.20509
Lacy-Hulbert A*, Ueno T*, Ito T, Jurewicz M, Izawa A, Smith RN, Chase CM, Tanaka K, Fiorina P, Russell PS, Auchincloss H, Sayegh MH, Hynes RO, Abdi R Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection. Am J Transplant. 2007;7(5):1080-90 - PMID: 17359504 - DOI: 10.1111/j.1600-6143.2007.01757.x
Yamaura K, Boenisch O, Watanabe T, Ueno T, Vanguri V, Yang J, Tanaka K, Guleria I, Borst J, Zhai Y, Kupiec-Weglinski JW, Najafian N Differential Requirement of CD27 Costimulatory Signaling for Naive Versus Alloantigen-Primed Effector/Memory CD8(+) T Cells. Am J Transplant. 2010;10(5):1210-20 - PMID: 20353477 - PMCID: PMC2889922 - DOI: 10.1111/j.1600-6143.2010.03089.x
Jurewicz M, Ueno T, Azzi J, Tanaka K, Murayama T, Yang S, Sayegh MH, Niimi M, Abdi R Donor Antioxidant Strategy Prolongs Cardiac Allograft Survival by Attenuating Tissue Dendritic Cell Immunogenicity. Am J Transplant. 2010;11(2):348-355 - PMID: 21182586 - DOI: 10.1111/j.1600-6143.2010.03360.x
Starling RC, Stehlik J, Baran DA, Armstrong B, Stone JR, Ikle D, Morrison Y, Bridges ND, Putheti P, Strom TB, Bhasin M, Guleria I, Chandraker A, Sayegh M, Daly KP, Briscoe DM, Heeger PS, Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study. Am J Transplant. 2015;16(1):121-36 - PMID: 26260101 - PMCID: PMC4948061 - DOI: 10.1111/ajt.13422
Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, Klöppel G, Heathcote JG, Khosroshahi A, Ferry JA, Aalberse RC, Bloch DB, Brugge WR, Bateman AC, Carruthers MN, Chari ST, Cheuk W, Cornell LD, Fernandez-Del Castillo C, Forcione DG, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Lauwers GY, Masaki Y, Nakanuma Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani DV, Smyrk TC, Stone JR, Takahira M, Webster GJ, Yamamoto M, Zamboni G, Umehara H, Stone JH Consensus statement on the pathology of IgG4-related disease. Mod Pathol. 2012;25(9):1181-92 - PMID: 22596100 - DOI: 10.1038/modpathol.2012.72
Siddiquee Z, Smith RN, Stone JR An elevated IgG4 response in chronic infectious aortitis is associated with aortic atherosclerosis. Mod Pathol. 2015;28(11):1428-34 - PMID: 26336884 - DOI: 10.1038/modpathol.2015.105
Zaharchuk G, Mandeville JB, Bogdanov AA Jr, Weissleder R, Rosen BR, Marota JJ Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension Stroke. 1999;30:2197-204; discussion 2204-5 - PMID: 10512929 - DOI: 10.1161/01.str.30.10.2197
Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine Model Stroke. 2004;35:952-7 - PMID: 14988578 - DOI: 10.1161/01.STR.0000120308.21946.5D
Kim DE, Kim JY, Nahrendorf M, Lee SK, Ryu JH, Kim K, Kwon IC, Schellingerhout D Direct Thrombus Imaging as a Means to Control the Variability of Mouse Embolic Infarct Models: The Role of Optical Molecular Imaging. Stroke. 2011;42(12):3566-73 - PMID: 22020025 - DOI: 10.1161/STROKEAHA.111.629428
Law B, Curino A, Bugge TH, Weissleder R, Tung CH Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter. Chem Biol. 2004;11(1):99-106 - PMID: 15112999 - DOI: 10.1016/j.chembiol.2003.12.017
Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L Covalent Reactions of Wortmannin under Physiological Conditions. Chem Biol. 2007;14(3):321-8 - PMID: 17379147 - DOI: 10.1016/j.chembiol.2007.02.007
Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chem Biol. 2007;14:1221-31 - PMID: 18022561 - PMCID: PMC2785040 - DOI: 10.1016/j.chembiol.2007.10.005
Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors. Chem Biol. 2011;18(12):1602-10 - PMID: 22195562 - PMCID: PMC3474356 - DOI: 10.1016/j.chembiol.2011.09.016
Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN A robust small-molecule microarray platform for screening cell lysates. Chem Biol. 2006;13(5):493-504 - PMID: 16720270 - DOI: 10.1016/j.chembiol.2006.03.004
Kozloff KM, Weissleder R, Mahmood U Non-Invasive Optical Detection of Bone Mineral. J Bone Miner Res. 2007;(22) 8:1208-1216 - PMID: 17488196 - DOI: 10.1359/jbmr.070504
Turan S, Fernandez-Rebollo E, Aydin C, Zoto T, Reyes M, Bounoutas G, Chen M, Weinstein LS, Erben RG, Marshansky V, Bastepe M Postnatal establishment of allelic Gαs silencing as a plausible explanation for delayed onset of parathyroid hormone-resistance due to heterozygous Gαs disruption. J Bone Miner Res. 2014;29(3):749-60 - PMID: 23956044 - PMCID: PMC3926912 - DOI: 10.1002/jbmr.2070
Quillard T, Croce K, Jaffer FA, Weissleder R, Libby P Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo. Thromb Haemostasis. 2011;105(5):828-36 - PMID: 21225096 - PMCID: PMC3087830 - DOI: 10.1160/TH10-09-0589
Tsourkas A, Newton G, Perez JM, Basilion J, Weissleder R. Detection of Peroxidase-Mediated Dityrosine Formation with Enhanced Yellow Fluorescent Protein Anal Chem. 2005;77:2862-2867 - PMID: 15859603 - DOI: 10.1021/ac0480747
Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L Multiparameter Magnetic Relaxation Switch Assays. Anal Chem. 2007;(79) 23:8863-9 - PMID: 17983206 - DOI: 10.1021/ac701976p
Koh I, Hong R, Weissleder R, Josephson L Nanoparticle-Target Interactions Parallel Antibody-Protein Interactions. Anal Chem. 2009;81(9):3618-22 - PMID: 19323458 - PMCID: PMC2690647 - DOI: 10.1021/ac802717c
Niers JM, Chen JW, Weissleder R, Tannous BA Enhanced in Vivo Imaging of Metabolically Biotinylated Cell Surface Reporters. Anal Chem. 2011;83(3):994-9 - PMID: 21214190 - PMCID: PMC3059349 - DOI: 10.1021/ac102758m
Roussakis E, Spencer JA, Lin CP, Vinogradov SA Two-Photon Antenna-Core Oxygen Probe with Enhanced Performance. Anal Chem. 2014;86(12):5937-45 - PMID: 24848643 - PMCID: PMC4066907 - DOI: 10.1021/ac501028m
Wittenberg NJ, Im H, Xu X, Wootla B, Watzlawik J, Warrington AE, Rodriguez M, Oh SH High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance. Anal Chem. 2012;84(14):6031-9 - PMID: 22762372 - PMCID: PMC3417152 - DOI: 10.1021/ac300819a
Im H, Sutherland JN, Maynard JA, Oh SH Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics. Anal Chem. 2012;84(4):1941-7 - PMID: 22235895 - PMCID: PMC3307221 - DOI: 10.1021/ac300070t
Im H, Lesuffleur A, Lindquist NC, Oh SH Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing. Anal Chem. 2009;81(8):2854-9 - PMID: 19284776 - PMCID: PMC2720634 - DOI: 10.1021/ac802276x
Sosnovik DE, Nahrendorf M, Weissleder R Targeted imaging of myocardial damage. Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275 - DOI: 10.1038/ncpcardio1115
Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R Advances in measuring single-cell pharmacokinetics and pharmacology in vivo. Drug Discov Today. 2015;20(9):1087-92 - PMID: 26024776 - PMCID: PMC4567932 - DOI: 10.1016/j.drudis.2015.05.011
Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476 - DOI: 10.1161/CIRCEP.108.778357
Sosnovik DE, Nahrendorf M, Weissleder R Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271 - DOI: 10.1007/s00395-008-0710-7
Nahrendorf M, Sosnovik DE, Weissleder R MR-optical imaging of cardiovascular molecular targets. Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635 - DOI: 10.1007/s00395-008-0707-2
Groen A, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison T A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci. 2008;121(Pt 14):2293-300 - PMID: 18559893 - PMCID: PMC2902979 - DOI: 10.1242/jcs.024018
Zilberman Y, Ballestrem C, Carramusa L, Mazitschek R, Khochbin S, Bershadsky A Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6. J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819 - DOI: 10.1242/jcs.046813
Tran AD, Marmo TP, Salam AA, Che S, Finkelstein E, Kabarriti R, Xenias HS, Mazitschek R, Hubbert C, Kawaguchi Y, Sheetz MP, Yao TP, Bulinski JC HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions. J Cell Sci. 2007;120(Pt 8):1469-79 - PMID: 17389687 - DOI: 10.1242/jcs.03431
Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation via the ZONAB pathway. J Cell Sci. 2014;127(Pt 20):4396-408 - PMID: 25107366 - PMCID: PMC4197086 - DOI: 10.1242/jcs.148098
Faris JE, Blaszkowsky LS, McDermott S, Guimaraes AR, Szymonifka J, Huynh MA, Ferrone CR, Wargo JA, Allen JN, Dias LE, Kwak EL, Lillemoe KD, Thayer SP, Murphy JE, Zhu AX, Sahani DV, Wo JY, Clark JW, Fernandez-Del Castillo C, Ryan DP, Hong TS FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience. Oncologist. 2013;18(5):543-548 - PMID: 23657686 - PMCID: PMC3662845 - DOI: 10.1634/theoncologist.2012-0435
Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA and Gropler RJ Multimodality Cardiovascular Molecular Imaging, Part I Circ Cardiovasc Imaging. 2008;1(3):244-256 - PMID: 19808549 - DOI: 10.1161/CIRCIMAGING.108.824359
Nahrendorf M, Sosnovik D, French B, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ Multimodality Cardiovascular Molecular Imaging, Part II Circ Cardiovasc Imaging. 2009;2:56-70 - PMID: 19808565 - PMCID: PMC2760054 - DOI: 10.1161/CIRCIMAGING.108.839092
Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ and Wedeen VJ Diffusion Spectrum MRI Tractography Reveals the Presence of a Complex Network of Residual Myofibers in Infarcted Myocardium Circ Cardiovasc Imaging. 2009;2:206-212 - PMID: 19808594 - PMCID: PMC2760045 - DOI: 10.1161/CIRCIMAGING.108.815050
Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A Molecular MRI Detects Low Levels of Cardiomyocyte Apoptosis in a Transgenic Model of Chronic Heart Failure. Circ Cardiovasc Imaging. 2009;2(6):468-475 - PMID: 19920045 - PMCID: PMC2782621 - DOI: 10.1161/CIRCIMAGING.109.863779
Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia. Circ Cardiovasc Imaging. 2009;2(6):460-467 - PMID: 19920044 - PMCID: PMC2780438 - DOI: 10.1161/CIRCIMAGING.109.859678
Nordbeck P, Hiller KH, Fidler F, Warmuth M, Burkard N, Nahrendorf M, Jakob PM, Quick HH, Ertl G, Bauer WR, Ritter O Feasibility of Contrast Enhanced and Non-Enhanced MRI for Intra- and Postprocedural Lesion Visualization in Interventional Electrophysiology: Animal Studies and Early Delineation of Isthmus Ablation Lesions in Patients with Typical Atrial Flutter. Circ Cardiovasc Imaging. 2011;4(3):282-94 - PMID: 21415125 - DOI: 10.1161/CIRCIMAGING.110.957670
Nahrendorf M Imaging of infarct healing predicts left ventricular remodeling and evolution of heart failure: focus on protease activity. Circ Cardiovasc Imaging. 2011;4(4):351-3 - PMID: 21772011 - PMCID: PMC3141180 - DOI: 10.1161/CIRCIMAGING.111.966671
Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE Molecular MRI of Acute Necrosis with a Novel DNA-Binding Gadolinium Chelate: Kinetics of Cell Death and Clearance in Infarcted Myocardium. Circ Cardiovasc Imaging. 2011;4(6):729-737 - PMID: 21836081 - PMCID: PMC3370828 - DOI: 10.1161/CIRCIMAGING.111.966374
Sosnovik DE, Nahrendorf M Cells and Iron Oxide Nanoparticles on the Move: Magnetic Resonance Imaging of Monocyte Homing and Myocardial Inflammation in Patients With ST-Elevation Myocardial Infarction. Circ Cardiovasc Imaging. 2012;5(5):551-4 - PMID: 22991284 - PMCID: PMC3529959 - DOI: 10.1161/CIRCIMAGING.112.978932
Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE Fluorescence Tomography of Rapamycin-Induced Autophagy and Cardioprotection In Vivo. Circ Cardiovasc Imaging. 2013;6(3):441-7 - PMID: 23537953 - PMCID: PMC3805276 - DOI: 10.1161/CIRCIMAGING.112.000074
Ueno T, Dutta P, Keliher E, Leuschner F, Majmudar M, Marinelli B, Iwamoto Y, Figueiredo JL, Christen T, Swirski FK, Libby P, Weissleder R, Nahrendorf M Nanoparticle PET-CT Detects Rejection and Immunomodulation in Cardiac Allografts. Circ Cardiovasc Imaging. 2013;6(4):568-73 - PMID: 23771986 - PMCID: PMC3734553 - DOI: 10.1161/CIRCIMAGING.113.000481
Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P Increased Microvascularization and Vessel Permeability Associate with Active Inflammation in Human Atheromata. Circ Cardiovasc Imaging. 2014;7(6):920-929 - PMID: 25170063 - PMCID: PMC4237630 - DOI: 10.1161/CIRCIMAGING.114.002113
Nahrendorf M, Swirski FK Imaging systemic inflammation in patients with acute myocardial infarction. Circ Cardiovasc Imaging. 2014;7(5):762-4 - PMID: 25227235 - DOI: 10.1161/CIRCIMAGING.114.002410
Libby P, DiCarli M, Weissleder R The Vascular Biology of Atherosclerosis and Imaging Targets. J Nucl Med. 2010;51 Suppl 1:33S-37S - PMID: 20395349 - DOI: 10.2967/jnumed.109.069633
Kramer CM, Sinusas AJ, Sosnovik DE, French BA, Bengel FM Multimodality Imaging of Myocardial Injury and Remodeling. J Nucl Med. 2010;51 Suppl 1:107S-121S - PMID: 20395347 - PMCID: PMC3078824 - DOI: 10.2967/jnumed.109.068221
Bogdanov AA, Callahan RJ, Wilkinson RA, Martin C, Cameron JA, Fischman AJ, Brady TJ, Weissleder R Synthetic copolymer kit for radionuclide blood-pool imaging. J Nucl Med. 1994;35(11):1880-6 - PMID: 7965173
Majmudar MD, Nahrendorf M Cardiovascular Molecular Imaging: The Road Ahead. J Nucl Med. 2012;53(5):673-676 - PMID: 22492729 - PMCID: PMC3744821 - DOI: 10.2967/jnumed.111.099838
Zeglis BM, Sevak KK, Reiner T, Mohindra P, Carlin SD, Zanzonico P, Weissleder R, Lewis JS A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry. J Nucl Med. 2013;54(8):1389-96 - PMID: 23708196 - PMCID: PMC4151562 - DOI: 10.2967/jnumed.112.115840
Nahrendorf M, Wiesmann F, Hiller K, Han H, Hu K, Waller C, Ruff J, Haase A, Ertl G, Bauer W In vivo assessment of cardiac remodeling after myocardial infarction in rats by cine-magnetic resonance imaging. J Cardiovasc Magn Reson. 2001;2(3):171-80 - PMID: 11545114 - DOI: 10.3109/10976640009146565
Sosnovik DE, Caravan P Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents J Cardiovasc Magn Reson. 2009;2:87-94
Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ Diffusion MR tractography of the heart. J Cardiovasc Magn Reson. 2009;11(1):47 - PMID: 19912654 - PMCID: PMC2781805 - DOI: 10.1186/1532-429X-11-47
Mekkaoui C, Huang S, Chen HH, Dai G, Reese TG, Kostis WJ, Thiagalingam A, Maurovich-Horvat P, Ruskin JN, Hoffmann U, Jackowski MP, Sosnovik DE Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation. J Cardiovasc Magn Reson. 2012;14(1):70 - PMID: 23061749 - PMCID: PMC3506570 - DOI: 10.1186/1532-429X-14-70
Law B, Weissleder R, Tung CH Peptide-based Biomaterials for Protease-Enhanced Drug Delivery Biomacromolecules. 2006;7(4):1261-1265 - PMID: 16602747 - DOI: 10.1021/bm050920f
Law B, Tung CH Structural modification of protease inducible preprogrammed nanofiber precursor. Biomacromolecules. 2008;9:421-5 - PMID: 18177006 - DOI: 10.1021/bm7012026
Yoshida S, Shimada M, Ueno T, Kitamura Y, Matsuzaki S, Nishikubo S, Nagae M, Nakanishi K, Murata J, Yoshino M Successful endoscopic submucosal dissection of duodenal cancer. Endoscopy. 2008;40 Suppl 2:E132-3 - PMID: 18633861 - DOI: 10.1055/s-2007-995685
Yoshida S, Shimada M, Ueno T, Kato A, Yoshino M Latex hand glove: a safe and convenient device for the endoscopic removal of foreign bodies. Endoscopy. 2008;40 Suppl 2:E195-6 - PMID: 18709613 - DOI: 10.1055/s-2008-1077420
Yoshida S, Shimada M, Ueno T, Yoshino M Exuberant mucosal granulation by a self-expanding metal stent leading to complete closure of esophageal perforation. Endoscopy. 2008;40 Suppl 2:E244-5 - PMID: 18991221 - DOI: 10.1055/s-2008-1077526
Park KS, Charles RC, Ryan ET, Weissleder R*, Lee H* Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease Chem Eur J. 2015;21(46):16359-63 - PMID: 26420633 - PMCID: PMC4816641 - DOI: 10.1002/chem.201502934
Schellenberger EA, Bogdanov A Jr, Petrovsky A, Ntziachristos V, Weissleder R, Josephson L Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy Neoplasia. 2003;5:187-92 - PMID: 12869301 - PMCID: PMC1502408 - DOI: 10.1016/S1476-5586(03)80050-7
Allport JR, Weissleder R Murine Lewis lung carcinoma-derived endothelium expresses markers of endothelial activation and requires tumor-specific extracellular matrix in vitro Neoplasia. 2003;5:205-17 - PMID: 12869304 - PMCID: PMC1502407 - DOI: 10.1016/S1476-5586(03)80053-2
Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2 Neoplasia. 2002;4:501-9 - PMID: 12407444 - PMCID: PMC1503664 - DOI: 10.1038/sj.neo.7900265
Melder RJ, Munn LL, Stoll BR, Marecos EM, Baxter LT, Weissleder R, Jain RK Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: comparison with physiologically based pharmacokinetic model Neoplasia. 2002;4:3-8 - PMID: 11922388 - PMCID: PMC1503314 - DOI: 10.1038/sj/neo/7900209
Ichikawa T, Hogemann D, Saeki Y, Tyminski E, Terada K, Weissleder R, Chiocca EA, Basilion JP MRI of transgene expression: correlation to therapeutic gene expression Neoplasia. 2002;4:523-30 - PMID: 12407446 - PMCID: PMC1503666 - DOI: 10.1038/sj.neo.7900266
Bogdanov AA Jr, Lin CP, Simonova M, Matuszewski L, Weissleder R Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment Neoplasia. 2002;4:228-36 - PMID: 11988842 - PMCID: PMC1531696 - DOI: 10.1038/sj/neo/7900238
Bogdanov A Jr, Marecos E, Cheng HC, Chandrasekaran L, Krutzsch HC, Roberts DD, Weissleder R Treatment of experimental brain tumors with trombospondin-1 derived peptides: an in vivo imaging study Neoplasia. 1999;1:438-45 - PMID: 10933059 - PMCID: PMC1508110 - DOI: 10.1038/sj.neo.7900044
Hogemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP. The transferrin receptor: a potential molecular imaging marker for human cancer. Neoplasia. 2003;5(6):495-506 - PMID: 14965443 - PMCID: PMC1502574 - DOI: 10.1016/s1476-5586(03)80034-9
Messerli SM, Prabhakar S, Tang Y, Shah K, Cortes ML, Murthy V, Weissleder R, Breakefield XO, Tung CH A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. Neoplasia. 2004;6(2):95-105 - PMID: 15140398 - PMCID: PMC1502090 - DOI: 10.1593/neo.03214
Shinde Patil VR, Friedrich EB, Wolley AE, Gerszten RE, Allport JR, Weissleder R. Bone Marrow-Derived lin(-)c-kit(+)Sca-1(+) Stem Cells Do Not Contribute to Vasculogenesis in Lewis Lung Carcinoma Neoplasia. 2005;7(3):234-40 - PMID: 15799823 - PMCID: PMC1501134 - DOI: 10.1593/neo.04523
Reichardt W, Hu-Lowe D, Torres D, Weissleder R, Bogdanov A Jr. Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model Neoplasia. 2005;7(9):847-53 - PMID: 16229807 - PMCID: PMC1351316 - DOI: 10.1593/neo.05139
Funovics M, Montet X, Reynolds F, Weissleder R, Josephson L. Nanoparticles for the Optical Imaging of Tumor E-selectin Neoplasia. 2005;7(10):904-11 - PMID: 16242073 - DOI: 10.1593/neo.05352
Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R Novel Multiwavelength Microscopic Scanner for Mouse Imaging. Neoplasia. 2005;7(11):977-983 - PMID: 16331883 - PMCID: PMC1502018 - DOI: 10.1593/neo.05376
Sato F, Fukuhara H, Basilion JP Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo. Neoplasia. 2005;7(9):838-46 - PMID: 16229806 - PMCID: PMC1501932 - DOI: 10.1593/neo.05145
Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L. Nanoparticle Imaging of Integrins on Tumor Cells Neoplasia. 2006;8(3):214-222 - PMID: 16611415 - PMCID: PMC1578521 - DOI: 10.1593/neo.05769
Trehin R, Figueiredo JL, Pittet M, Weissleder R, Josephson L, Mahmood U. Fluorescent Nanoparticle Uptake for Brain Tumor Visualization Neoplasia. 2006;8(4):302-311 - PMID: 16756722 - PMCID: PMC1600680 - DOI: 10.1593/neo.05751
Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006;8(9):772-80 - PMID: 16984734 - PMCID: PMC1584300 - DOI: 10.1593/neo.06331
Kelly KA, Waterman P, Weissleder R. In vivo imaging of molecularly targeted phage Neoplasia. 2006;8 (12):1011-1018
Kock N, Kasmieh R, Weissleder R, Shah K Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL. Neoplasia. 2007;9(5):435-42 - PMID: 17534449 - PMCID: PMC1877976 - DOI: 10.1593/neo.07223
Harisinghani M, Ross R, Guimaraes A, Weissleder R Utility of a New Bolus-Injectable Nanoparticle for Clinical Cancer Staging Neoplasia. 2007;(9)12:1160-1165 - PMID: 18084623 - PMCID: PMC2134912 - DOI: 10.1593/neo.07940
Kelly K, Jones D Isolation of a colon tumor specific binding peptide using phage display selection. Neoplasia. 2003;5:437-44 - PMID: 14670181 - PMCID: PMC1550331 - DOI: 10.1016/s1476-5586(03)80046-5
Perez JM, Grimm J, Josephson L, Weissleder R Integrated nanosensors to determine levels and functional activity of human telomerase. Neoplasia. 2008;10(10):1066-72 - PMID: 18813356 - PMCID: PMC2546593 - DOI: 10.1593/neo.08350
Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton A, Waterman P, Figueiredo JL, Kohler R, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle Neoplasia. 2009;11(5):459-468 - PMID: 19412430 - PMCID: PMC2672160 - DOI: 10.1593/neo.09356
Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents Neoplasia. 2012;14(3):169-177 - PMID: 22496617 - PMCID: PMC3323895 - DOI: 10.1593/neo.12414
Ghazani AA, Castro CM, Gorbatov R, Lee H, Weissleder R Sensitive and Direct Detection of Circulating Tumor Cells by Multimarker µ-Nuclear Magnetic Resonance. Neoplasia. 2012;14(5):388-95 - PMID: 22745585 - PMCID: PMC3384426 - DOI: 10.1596/neo.12696
Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R Targeting cathepsin e in pancreatic cancer by a small molecule allows in vivo detection. Neoplasia. 2013;15(7):684-93 - PMID: 23814481 - PMCID: PMC3689232 - DOI: 10.1593/neo.13276
Frantz S, Hofmann U, Fraccarollo D, Schäfer A, Kranepuhl S, Hagedorn I, Nieswandt B, Nahrendorf M, Wagner H, Bayer B, Pachel C, Schön MP, Kneitz S, Bobinger T, Weidemann F, Ertl G, Bauersachs J Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction. FASEB J. 2013;27(3):871-81 - PMID: 23159933 - DOI: 10.1096/fj.12-214049
Kim DE, Jaffer FA, Weissleder R, Tung CH, Schellingerhout D. Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis J Cereb Blood Flow Metab. 2005;25(2):226-33 - PMID: 15678125 - DOI: 10.1038/sj.jcbfm.9600023
Forghani R, Kim HJ, Wojtkiewicz GR, Bure L, Wu Y, Hayase M, Wei Y, Zheng Y, Moskowitz MA, Chen JW Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke. J Cereb Blood Flow Metab. 2014;35(3):485-93 - PMID: 25515211 - PMCID: PMC4348390 - DOI: 10.1038/jcbfm.2014.222
Robbins CS, Swirski FK The multiple roles of monocyte subsets in steady state and inflammation. Cell Mol Life Sci. 2010;67(16):2685-93 - PMID: 20437077 - DOI: 10.1007/s00018-010-0375-x
Mahmood U, Weissleder R Near-infrared optical imaging of proteases in cancer Mol Cancer Ther. 2003;2:489-96 - PMID: 12748311
Law B, Quinti L, Choi YD, Weissleder R, Tung CH A Mitochondrial Targeted Fusion Peptide Exhibits Remarkable Cytotoxicity Mol Cancer Ther. 2006;5 (8):1944-1949 - PMID: 16928814 - DOI: 10.1158/1535-7163.MCT-05-0509
Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol Cancer Ther. 2008;7(11):3575-85 - PMID: 19001440 - PMCID: PMC2748233 - DOI: 10.1158/1535-7163.MCT-08-0640
Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, Garcia-Anoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO Mutant Sodium Channel for Tumor Therapy. Mol Cancer Ther. 2009;17(5):810-9 - PMID: 19259066 - PMCID: PMC2751883 - DOI: 10.1038/mt.2009.33
Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L The antiproliferative cytostatic effects of a self-activating viridin prodrug. Mol Cancer Ther. 2009;8(6):1666-1675 - PMID: 19509266 - PMCID: PMC2740925 - DOI: 10.1158/1535-7163.MCT-08-1012
Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1. Mol Cancer Ther. 2009;18(2):285-94 - PMID: 19844198 - PMCID: PMC2818668 - DOI: 10.1038/mt.2009.232
Emdad L, Sarkar D, Lee SG, Su ZZ, Yoo BK, Dash R, Yacoub A, Fuller CE, Shah K, Dent P, Bruce JN, Fisher PB Astrocyte elevated gene-1: a novel target for human glioma therapy. Mol Cancer Ther. 2010;9(1):79-88 - PMID: 20053777 - PMCID: PMC3165052 - DOI: 10.1158/1535-7163.MCT-09-0752
Thurber G, Reiner T, Yang K, Kohler R, Weissleder R Effect of Small Molecule Modification on Single Cell Pharmacokinetics of PARP Inhibitors. Mol Cancer Ther. 2014;13(4):986-95 - PMID: 24552776 - PMCID: PMC3981972 - DOI: 10.1158/1535-7163.MCT-13-0801
Framme C, Alt C, Schnell S, Brinkmann R, Lin CP [Selective RPE laser treatment with a scanned cw laser beam in rabbits] Ophthalmologie. 2005;102(5):491-6 - PMID: 15883846 - DOI: 10.1007/s00347-004-1139-5
Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palu G, Irimia D, Toner M, Weissleder R, Poznansky MC Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control. J Immunol. 2006;176(5):2902-14 - PMID: 16493048 - DOI: 10.4049/jimmunol.176.5.2902
Campanella GS, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewicz GR, Weissleder R, Luster AD Oligomerization of CXCL10 Is Necessary for Endothelial Cell Presentation and In Vivo Activity. J Immunol. 2006;177:6991-8 - PMID: 17082614 - DOI: 10.4049/jimmunol.177.10.6991
Pittet M, Gati A, Le Gal F, Bioley G, Guillaume P, de Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Zippelius A Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex. J Immunol. 2006;176:2330-6 - PMID: 16455990 - DOI: 10.4049/jimmunol.176.4.2330
Zippelius A, Bioley G, Le Gal F, Rufer N, Brandes M, Batard P, De Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Pittet M Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J Immunol. 2004;172:2773-7 - PMID: 14978076 - DOI: 10.4049/jimmunol.172.5.2773
Pittet M, Rubio-Godoy V, Bioley G, Guillaume P, Batard P, Speiser D, Luescher I, Cerottini J, Romero P, Zippelius A Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells. J Immunol. 2003;171:1844-9 - PMID: 12902485 - DOI: 10.4049/jimmunol.171.4.1844
Dietrich P, Le Gal F, Dutoit V, Pittet M, Trautman L, Zippelius A, Cognet I, Widmer V, Walker P, Michielin O, Guillaume P, Connerotte T, Jotereau F, Coulie P, Romero P, Cerottini J, Bonneville M, Valmori D Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen. J Immunol. 2003;170:5103-9 - PMID: 12734356 - DOI: 10.4049/jimmunol.170.10.5103
Valmori D, Dutoit V, Schnuriger V, Quiquerez A, Pittet M, Guillaume P, Rubio-Godoy V, Walker P, Rimoldi D, Lienard D, Cerottini J, Romero P, Dietrich P Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity. J Immunol. 2002;168:4231-40 - PMID: 11937585 - DOI: 10.4049/jimmunol.168.8.4231
Pittet M, Zippelius A, Speiser D, Assenmacher M, Guillaume P, Valmori D, Lienard D, Lejeune F, Cerottini J, Romero P Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases. J Immunol. 2001;166:7634-40 - PMID: 11390521 - DOI: 10.4049/jimmunol.166.12.7634
Speiser D, Colonna M, Ayyoub M, Cella M, Pittet M, Batard P, Valmori D, Guillaume P, Lienard D, Cerottini J, Romero P The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells. J Immunol. 2001;167:6165-70 - PMID: 11714776 - DOI: 10.4049/jimmunol.167.11.6165
Pittet M, Speiser D, Valmori D, Cerottini J, Romero P Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression. J Immunol. 2000;164:1148-52 - PMID: 10640724 - DOI: 10.4049/jimmunol.164.3.1148
Alvarez D, Swirski F, Yang T, Fattouh R, Croitoru K, Bramson J, Stampfli M, Jordana M Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues. J Immunol. 2006;176(4):2568-80 - PMID: 16456019 - DOI: 10.4049/jimmunol.176.4.2568
Gajewska B, Tafuri A, Swirski F, Walker T, Johnson J, Shea T, Shahinian A, Goncharova S, Mak T, Stampfli M, Jordana M B7RP-1 is not required for the generation of Th2 responses in a model of allergic airway inflammation but is essential for the induction of inhalation tolerance. J Immunol. 2005;174(5):3000-5 - PMID: 15728513 - DOI: 10.4049/jimmunol.174.5.3000
Swirski F, Sajic D, Robbins C, Gajewska B, Jordana M, Stampfli M Chronic exposure to innocuous antigen in sensitized mice leads to suppressed airway eosinophilia that is reversed by granulocyte macrophage colony-stimulating factor. J Immunol. 2002;169:3499-506 - PMID: 12244139 - DOI: 10.4049/jimmunol.169.7.3499
Romero P, Zippelius A, Kurth I, Pittet M, Touvrey C, Iancu E, Corthesy P, Devevre E, Speiser D, Rufer N Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes. J Immunol. 2007;178(7):4112-9 - PMID: 17371966 - DOI: 10.4049/jimmunol.178.7.4112
Ito T*, Ueno T*, Clarkson MR, Yuan X, Jurewicz MM, Yagita H, Azuma M, Sharpe AH, Auchincloss H, Sayegh MH, Najafian N Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo. J Immunol. 2005;174(11):6648-56 - PMID: 15905503 - DOI: 10.4049/jimmunol.174.11.6648
Izawa A, Yamaura K, Albin MJ, Jurewicz M, Tanaka K, Clarkson MR, Ueno T, Habicht A, Freeman GJ, Yagita H, Abdi R, Pearson T, Greiner DL, Sayegh MH, Najafian N A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo. J Immunol. 2007;179(2):786-96 - PMID: 17617568 - DOI: 10.4049/jimmunol.179.2.786
Tanaka K, Albin MJ, Yuan X, Yamaura K, Habicht A, Murayama T, Grimm M, Waaga AM, Ueno T, Padera RF, Yagita H, Azuma M, Shin T, Blazar BR, Rothstein DM, Sayegh MH, Najafian N PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol. 2007;179(8):5204-10 - PMID: 17911605 - PMCID: PMC2291549 - DOI: 10.4049/jimmunol.179.8.5204
Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N TIM-3: a novel regulatory molecule of alloimmune activation. J Immunol. 2010;185(10):5806-19 - PMID: 20956339 - PMCID: PMC3619947 - DOI: 10.4049/jimmunol.0903435
Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages. J Immunol. 2011;186(3):1369-76 - PMID: 21187450 - PMCID: PMC3670585 - DOI: 10.4049/jimmunol.1002047
Zhi L, Kim P, Thompson BD, Pitsillides C, Bankovich AJ, Yun SH, Lin CP, Cyster JG, Wu MX FTY720 Blocks Egress of T Cells in Part by Abrogation of Their Adhesion on the Lymph Node Sinus. J Immunol. 2011;187(5):2244-51 - PMID: 21788441 - PMCID: PMC3167479 - DOI: 10.4049/jimmunol.1100670
Marshansky V, Wang X, Bertrand R, Luo H, Duguid W, Chinnadurai G, Kanaan N, Vu MD, Wu J Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells. J Immunol. 2001;166(5):3130-42 - PMID: 11207265 - DOI: 10.4049/jimmunol.166.5.3130
Riella LV*, Ueno T*, Batal I, De Serres SA, Bassil R, Elyaman W, Yagita H, Medina-Pestana JO, Chandraker A, Najafian N Blockade of notch ligand delta1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation. J Immunol. 2011;187(9):4629-38 - PMID: 21949024 - PMCID: PMC3197868 - DOI: 10.4049/jimmunol.1004076
Li HW, Andreola G, Carlson AL, Shao S, Lin CP, Zhao G, Sykes M Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation. J Immunol. 2015;195(3):1282-92 - PMID: 26085679 - PMCID: PMC4506852 - DOI: 10.4049/jimmunol.1401511
Misaghi S, Garris CS, Sun Y, Nguyen A, Zhang J, Sebrell A, Senger K, Yan D, Lorenzo MN, Heldens S, Lee WP, Xu M, Wu J, DeForge L, Sai T, Dixit VM, Zarrin AA Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells. J Immunol. 2010;185(1):166-73 - PMID: 20511552 - DOI: 10.4049/jimmunol.1000515
Hilgendorf I, Swirski FK Folate receptor: a macrophage "achilles' heel"? J Am Heart Assoc. 2012;1(4):e004036 - PMID: 23130179 - PMCID: PMC3487350 - DOI: 10.1161/JAHA.112.004036
Bremer C, Ntziachristos V, Weitkamp B, Theilmeier G, Heindel W, Weissleder R. Optical Imaging of Spontaneous Breast Tumors Using Protease Sensing Invest Radiol. 2005;(6):321-327 - PMID: 15905717 - DOI: 10.1097/01.rli.0000163797.23172.90
Frank H, Loewe R, Loewe C, Oberhuber G, Schwaighofer B, Huber K, Weissleder R Efficacy of thrombolytic therapy in pulmonary embolism determined by MION-enhanced MRA: an experimental study in rabbits. Invest Radiol. 1998;33(12):853-7 - PMID: 9851818 - DOI: 10.1097/00004424-199812000-00002
Cheng HC, Khan MA, Bogdanov A, Kwong K, Weissleder R Relative blood volume measurements by magnetic resonance imaging facilitate detection of testicular torsion. Invest Radiol. 1997;32(12):763-9 - PMID: 9406017 - DOI: 10.1097/00004424-199712000-00007
Schulze E, Ferrucci JT, Poss K, Lapointe L, Bogdanova A, Weissleder R Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro. Invest Radiol. 1995;30(10):604-10 - PMID: 8557500 - DOI: 10.1097/00004424-199510000-00006
Weissleder R, Bogdanov A, Frank H, Nossiff N, Bogdanova A, Schaffer BK, Brady T, Wittenberg J AUR Memorial Award 1993. A drug system (PDH) for interventional radiology. Synthesis, properties, and efficacy. Invest Radiol. 1993;28(12):1083-9 - PMID: 8307710 - DOI: 10.1097/00004424-199312000-00001
Reimer P, Weissleder R, Nickeleit V, Brady TJ Animal models for magnetic resonance imaging research of the liver. Invest Radiol. 1992;27(5):390-3 - PMID: 1582824 - DOI: 10.1097/00004424-199205000-00014
Grüber G, Marshansky V New insights into structure-function relationships between archeal ATP synthase (A1A0) and vacuolar type ATPase (V1V0). Bioessays. 2008;30(11-12):1096-109 - PMID: 18937357 - DOI: 10.1002/bies.20827
Libby P, Nahrendorf M, Swirski FK Monocyte heterogeneity in cardiovascular disease. Semin Immunopathol. 2013;35(5):553-62 - PMID: 23839097 - PMCID: PMC3755757 - DOI: 10.1007/s00281-013-0387-3
Swirski FK, Hilgendorf I, Robbins CS From proliferation to proliferation: monocyte lineage comes full circle. Semin Immunopathol. 2014;36(2):137-48 - PMID: 24435095 - PMCID: PMC3991755 - DOI: 10.1007/s00281-013-0409-1
Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption. Mol Cell Biol. 2006;26(11):4185-200 - PMID: 16705170 - PMCID: PMC1489079 - DOI: 10.1128/MCB.01055-05
Gabriely G, Wurdinger T, Kesari S, Esau C, Burchard J, Linsley P, Krichevsky A MiR-21 Promotes Glioma Invasion by Targeting MMP Regulators. Mol Cell Biol. 2008;28(17):5369-80 - PMID: 18591254 - PMCID: PMC2519720 - DOI: 10.1128/MCB.00479-08
Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes. Mol Cell Biol. 2010;31(2):351-64 - PMID: 21059868 - PMCID: PMC3019975 - DOI: 10.1128/MCB.00259-10
de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H, Bradner JE, Mazitschek R, Kozikowski AP, Matthias P, Hancock WW HDAC6 and HSP90 Control The Functions Of Foxp3+ T-Regulatory Cells. Mol Cell Biol. 2011;31(10):2066-78 - PMID: 21444725 - PMCID: PMC3133361 - DOI: 10.1128/MCB.05155-11
Li X, Isono K, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes. Mol Cell Biol. 2014;34(14):2773 - PMID: 24951669 - PMCID: PMC4097671
Aragon Han P, Olson MT, Fazeli R, Prescott JD, Pai SI, Schneider EB, Tufano RP, Zeiger MA The impact of molecular testing on the surgical management of patients with thyroid nodules. Ann Surg Oncol. 2014;21(6):1862-9 - PMID: 24522987 - DOI: 10.1245/s10434-014-3508-x
Fan KY, Gogineni H, Zaboli D, Lake S, Zahurak ML, Best SR, Levine MA, Tang M, Zinreich ES, Saunders JR, Califano JA, Blanco RG, Pai SI, Messing B, Ha PK Comparison of acute toxicities in two primary chemoradiation regimens in the treatment of advanced head and neck squamous cell carcinoma. Ann Surg Oncol. 2012;19(6):1980-7 - PMID: 22290566 - PMCID: PMC3715048 - DOI: 10.1245/s10434-012-2219-4
Pai SI Mission impossible: how HPV-associated head and neck cancers escape a primed immune response. Oral Oncol. 2013;49(8):723-5 - PMID: 23643070 - DOI: 10.1016/j.oraloncology.2013.03.453
Anderson KS, Gerber JE, D'Souza G, Pai SI, Cheng JN, Alam R, Kesiraju S, Chowell D, Gross ND, Haddad R, Gillison ML, Posner M Biologic predictors of serologic responses to HPV in oropharyngeal cancer: The HOTSPOT study. Oral Oncol. 2015;51(8):751-8 - PMID: 26094591 - PMCID: PMC4982366 - DOI: 10.1016/j.oraloncology.2015.05.007
Smith DF, Maleki Z, Coughlan D, Gooi Z, Akpeng B, Ogawa T, Bishop JA, Frick KD, Agrawal N, Gourin CG, Ha PK, Koch WM, Richmon JD, Westra WH, Pai SI Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay. Oral Oncol. 2014;50(6):600-4 - PMID: 24630260 - PMCID: PMC4318229 - DOI: 10.1016/j.oraloncology.2014.02.011
Joseph AW, Ogawa T, Bishop JA, Lyford-Pike S, Chang X, Phelps TH, Westra WH, Pai SI Molecular etiology of second primary tumors in contralateral tonsils of human papillomavirus-associated index tonsillar carcinomas. Oral Oncol. 2012;49(3):244-8 - PMID: 23062994 - PMCID: PMC3548989 - DOI: 10.1016/j.oraloncology.2012.09.009
Shah K, Breakefield XO HSV Amplicon Vectors for Cancer Therapy. Curr Gene Ther. 2006;6(3):361-70 - PMID: 16787187 - DOI: 10.2174/156652306777592063
Sun CC, Vaja V, Babitt JL, Lin HY Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation. Am J Hematol. 2012;87(4):392-400 - PMID: 22290531 - PMCID: PMC3653431 - DOI: 10.1002/ajh.23110
Golub MS, Hogrefe CE, Malka R, Higgins JM Developmental Plasticity of red blood cell homeostasis. Am J Hematol. 2014;89(5):459-66 - PMID: 24415575 - PMCID: PMC4086753 - DOI: 10.1002/ajh.23666
Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG Hereditary xerocytosis revisited. Am J Hematol. 2014;89(12):1142-1146 - PMID: 25044010 - PMCID: PMC4237618 - DOI: 10.1002/ajh.23799
Patel H, Patel H, Higgins JM Modulation of Red Blood Cell Population Dynamics is a Fundamental Homeostatic Response to Disease. Am J Hematol. 2015;90(5):422-8 - PMID: 25691355 - PMCID: PMC4717489 - DOI: 10.1002/ajh.23982
Babitt JL, Lin HY Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD. Am J Kidney Dis. 2010;55(4):726-41 - PMID: 20189278 - PMCID: PMC2905036 - DOI: 10.1053/j.ajkd.2009.12.030
Shayakul C, Breton S, Brown D, Alper SL Gene therapy of inherited renal tubular disease. Am J Kidney Dis. 1999;34(2):374-9 - PMID: 10430991 - DOI: 10.1016/s0272-6386(99)70372-0
Bishop JA, Maleki Z, Valsamakis A, Ogawa T, Chang X, Pai SI, Westra WH Application of the hybrid capture 2 assay to squamous cell carcinomas of the head and neck: a convenient liquid-phase approach for the reliable determination of human papillomavirus status. Cancer Cytopathol. 2011;120(1):18-25 - PMID: 21751428 - PMCID: PMC3197962 - DOI: 10.1002/cncy.20175
Gultepe E, Reynoso FJ, Jhaveri A, Kulkarni P, Nagesha D, Ferris C, Harisinghani M, Campbell RB, Sridhar S Monitoring of magnetic targeting to tumor vasculature through MRI and biodistribution. Nanomedicine (Lond). 2010;5(8):1173-82 - PMID: 21039195 - DOI: 10.2217/nnm.10.84
Chen HH, Feng Y, Zhang M, Chao W, Josephson L, Shaw SY, Sosnovik DE Protective Effect of the Apoptosis-Sensing Nanoparticle AnxCLIO-Cy5.5. Nanomedicine (Lond). 2011;8(3):291-298 - PMID: 21704591 - PMCID: PMC3319055 - DOI: 10.1016/j.nano.2011.06.012
McCarthy JR, Jaffer FA The role of nanomedicine in the imaging and therapy of thrombosis. Nanomedicine (Lond). 2011;6(8):1291-3 - PMID: 22026372 - PMCID: PMC3332076 - DOI: 10.2217/nnm.11.128
Weissleder R, Castro C Interview: Nanomedicine in oncology: miniaturized means to an enormous end. Nanomedicine (Lond). 2011;6(9):1495-8 - PMID: 22077461 - DOI: 10.2217/nnm.11.138
McCarthy JR, Sazonova IY, Erdem SS, Hara T, Thompson BD, Patel P, Botnaru I, Lin CP, Reed GL, Weissleder R, Jaffer FA Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy. Nanomedicine (Lond). 2012;7(7):1017-28 - PMID: 22348271 - PMCID: PMC3360120 - DOI: 10.2217/nnm.11.179
McCarthy JR Book review: the handbook of nanomedicine (2nd edition). Nanomedicine (Lond). 2013;8(2):173-5 - PMID: 23394153
Ghazani AA, McDermott S, Pectasides M, Sebas M, Mino-Kenudson M, Lee H, Weissleder R, Castro CM Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and miniaturized micro-NMR system. Nanomedicine (Lond). 2013;9(7):1009-17 - PMID: 23570873 - PMCID: PMC4330975 - DOI: 10.1016/j.nano.2013.03.011
King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA E2F3 plays an essential role in cardiac development and function. Cell Cycle. 2008;7(23):3775-80 - PMID: 19029823 - PMCID: PMC2723769 - DOI: 10.4161/cc.7.23.7240
Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006;64(4):589-97 - PMID: 16996355 - DOI: 10.1016/j.gie.2006.02.048
Stone JR Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease. Curr Opin Rheumatol. 2011;23(1):88-94 - PMID: 21037477 - DOI: 10.1097/BOR.0b013e3283412f7c
Unizony S, Stone JH, Stone JR New treatment strategies in large-vessel vasculitis. Curr Opin Rheumatol. 2013;25(1):3-9 - PMID: 23114585 - DOI: 10.1097/BOR.0b013e32835b133a
Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R Molecular imaging of myocardial infarction. J Mol Cell Cardiol. 2006;41:921-933 - PMID: 17067633 - DOI: 10.1016/j.yjmcc.2006.09.008
Nahrendorf M Macrophages in the infarct: fiery friends or friendly fire? J Mol Cell Cardiol. 2012;53(5):591-2 - PMID: 22975014 - DOI: 10.1016/j.yjmcc.2012.09.001
Hulsmans M, Sam F, Nahrendorf M Monocyte and macrophage contributions to cardiac remodeling. J Mol Cell Cardiol. 2015;93:149-55 - PMID: 26593722 - PMCID: PMC4846552 - DOI: 10.1016/j.yjmcc.2015.11.015
Shao F, Yuan H, Josephson L, Weissleder R, Hilderbrand SA Facile Synthesis of Monofunctional Pentamethine Carbocyanine Fluorophores. Dyes Pigm. 2011;90(2):119-122 - PMID: 21475610 - PMCID: PMC3070263 - DOI: 10.1016/j.dyepig.2010.12.008
Wang L, Trebicka E, Fu Y, Ellenbogen S, Hong CC, Babitt JL, Lin HY, Cherayil BJ The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease. Inflamm Bowel Dis. 2012;18(1):112-9 - PMID: 21351217 - PMCID: PMC3139830 - DOI: 10.1002/ibd.21675
Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA Fluorescence Endoscopy of Cathepsin Activity Discriminates Dysplasia from Colitis. Inflamm Bowel Dis. 2013;19(7):1339-1345 - PMID: 23591598 - PMCID: PMC4306589 - DOI: 10.1097/MIB.0b013e318281f3f8
Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP Normalization of Plasma 25-Hydroxy Vitamin D Is Associated with Reduced Risk of Surgery in Crohn's Disease. Inflamm Bowel Dis. 2013;19(9):1921-1927 - PMID: 23751398 - PMCID: PMC3720838 - DOI: 10.1097/MIB.0b013e3182902ad9
Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2015;21(11):2507-2514 - PMID: 26241000 - PMCID: PMC4615315 - DOI: 10.1097/MIB.0000000000000524
Byun H, Hillman TR, Higgins JM, Diez-Silva M, Peng Z, Dao M, Dasari RR, Suresh S, Park Y Optical measurement of biomechanical properties of individual erythrocytes from a sickle cell patient. Acta Biomater. 2012;8(11):4130-8 - PMID: 22820310 - PMCID: PMC3576574 - DOI: 10.1016/j.actbio.2012.07.011
Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006;12(5):797-806 - PMID: 16556935 - PMCID: PMC1440893 - DOI: 10.1261/rna.2300406
Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bunemann M Kinetics of G-protein-coupled receptor signals in intact cells. Brit J Pharmacol. 2008;153 Suppl 1:S125-32 - PMID: 18193071 - PMCID: PMC2268076 - DOI: 10.1038/sj.bjp.0707656
Bredow S, Lewin M, Hofmann B, Marecos E, Weissleder R Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin Eur J Cancer. 2000;36:675-81 - PMID: 10738134 - DOI: 10.1016/s0959-8049(99)00335-4
Weissleder R, Cheng HC, Marecos E, Kwong K, Bogdanov A Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions. Eur J Cancer. 1998;34(9):1448-54 - PMID: 9849430 - DOI: 10.1016/s0959-8049(98)00195-6
Stieber F, Grether U, Mazitschek R, Soric N, Giannis A, Waldmann H Multistep solid-phase synthesis of an antibiotic and receptor tyrosine kinase inhibitors using the traceless phenylhydrazide linker. Chemistry. 2003;9(14):3282-91 - PMID: 12866072 - DOI: 10.1002/chem.200304821
van der Laan AM, Nahrendorf M, Piek JJ Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response. Heart. 2012;98(18):1384-90 - PMID: 22904145 - DOI: 10.1136/heartjnl-2012-301623
Speiser D, Lienard D, Pittet M, Batard P, Rimoldi D, Guillaume P, Cerottini J, Romero P In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells. Eur J Immunol. 2002;32:731-41 - PMID: 11870617 - DOI: 10.1002/1521-4141(200203)32:3<731::AID-IMMU731>3.0.CO;2-H
Speiser D, Migliaccio M, Pittet M, Valmori D, Lienard D, Lejeune F, Reichenbach P, Guillaume P, Lascher I, Cerottini J, Romero P Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells. Eur J Immunol. 2001;31:459-66 - PMID: 11180110 - DOI: 10.1002/1521-4141(200102)31:2<459::aid-immu459>3.0.co;2-y
Speiser D, Valmori D, Rimoldi D, Pittet M, Lienard D, Cerundolo V, MacDonald H, Cerottini J, Romero P CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients. Eur J Immunol. 1999;29:1990-9 - PMID: 10382762 - DOI: 10.1002/(SICI)1521-4141(199906)29:06<1990::AID-IMMU1990>3.0.CO;2-9
Swirski F, Gajewska B, Robbins C, D'Sa A, Johnson J, Pouladi M, Inman M, Stampfli M Concomitant airway expression of granulocyte-macrophage colony-stimulating factor and decorin, a natural inhibitor of transforming growth factor-beta, breaks established inhalation tolerance. Eur J Immunol. 2004;34(9):2375-86 - PMID: 15307170 - DOI: 10.1002/eji.200425012
Pittet MJ, Swirski FK Monocytes link atherosclerosis and cancer. Eur J Immunol. 2011;41(9):2519-22 - PMID: 21952809 - PMCID: PMC3817567 - DOI: 10.1002/eji.201141727
Ueno T, Yeung MY, McGrath M, Yang S, Zaman N, Snawder B, Padera RF, Magee CN, Gorbatov R, Hashiguchi M, Azuma M, Freeman GJ, Sayegh MH, Najafian N Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses. Eur J Immunol. 2012;42(9):2343-53 - PMID: 22733595 - PMCID: PMC3822046 - DOI: 10.1002/eji.201242501
Galande A, Weissleder R, Tung CH. An Effective Method of On-Resin Disulfide Bond Formation in Peptides J Comb Chem. 2005;7:174-177 - PMID: 15762743 - DOI: 10.1021/cc049839r
Garanger E, Blois J, Hilderbrand SA, Shao F, Josephson L Divergent Oriented Synthesis For the Design of Reagents for Protein Conjugation. J Comb Chem. 2009;12(1):57-64 - PMID: 19928910 - PMCID: PMC2877490 - DOI: 10.1021/cc900141b
Weissleder R, Marfil A, Martinez HR, Rangel-Guerra RA Limb girdle type muscular dystrophy associated with a Wolff-Parkinson-White syndrome. J Neurol Neurosurg Psych. 1987;50(4):500-1 - PMID: 3585373 - PMCID: PMC1031899 - DOI: 10.1136/jnnp.50.4.500
Rabkin-Aikawa E, Aikawa M, Farber M, Kratz J, Garcia-Cardena G, Kouchoukos N, Mitchell M, Jonas R, Schoen F Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site. J Thorac Cardiovasc Surg. 2004;128:552-61 - PMID: 15457156 - DOI: 10.1016/j.jtcvs.2004.04.016
Wagner CA, L A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse. Pflug Arch Eur J Phy. 2003;446(5):623-32 - PMID: 12748863 - DOI: 10.1007/s00424-003-1082-3
Swirski F, Gajewska B, Alvarez D, Ritz S, Cundall M, Cates E, Coyle A, Gutierrez-Ramos J, Inman M, Jordana M, Stampfli M Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice. Clin Exp Allergy. 2002;32:411-21 - PMID: 11940072 - DOI: 10.1046/j.1365-2222.2002.01291.x
Pham W, Lai WF, Weissleder R, Tung CH High efficiency synthesis of a bioconjugatable near-infrared fluorochrome Bioconjug Chem. 2003;14:1048-51 - PMID: 13129411 - DOI: 10.1021/bc034070h
Moon, WK, Lin Y, O'Loughlin T, Tang Y, Kim DE, Weissleder R, Tung CH Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate Bioconjug Chem. 2003;14:539-45 - PMID: 12757377 - DOI: 10.1021/bc0340114
Koch AM, Reynolds F, Kircher MF, Merkle HP, Weissleder R, Josephson L Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells Bioconjug Chem. 2003;14:1115-21 - PMID: 14624624 - DOI: 10.1021/bc034123v
Zhao M, Kircher MF, Josephson L, Weissleder R Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake Bioconjug Chem. 2002;13:840-4 - PMID: 12121140 - DOI: 10.1021/bc0255236
Wunderbaldinger P, Josephson L, Weissleder R Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles Bioconjug Chem. 2002;13:264-8 - PMID: 11906263 - DOI: 10.1021/bc015563u
Lin Y, Weissleder R, Tung CH Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation Bioconjug Chem. 2002;13:605-10 - PMID: 12009952 - DOI: 10.1021/bc0155723
Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov A Jr Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture Bioconjug Chem. 2002;13:122-7 - PMID: 11792187 - DOI: 10.1021/bc0155521
Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes Bioconjug Chem. 2002;13:554-60 - PMID: 12009946 - DOI: 10.1021/bc015555d
Hogemann D, Ntziachristos V, Josephson L, Weissleder R High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes Bioconjug Chem. 2002;13:116-21 - PMID: 11792186 - DOI: 10.1021/bc015549h
Weissleder R, Bogdanov A Jr, Tung CH, Weinmann HJ Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging Bioconjug Chem. 2001;12:213-9 - PMID: 11312682 - DOI: 10.1021/bc000091p
Hogemann D, Josephson L, Weissleder R, Basilion JP Improvement of MRI probes to allow efficient detection of gene expression Bioconjug Chem. 2000;11:941-6 - PMID: 11087345 - DOI: 10.1021/bc000079x
Bhorade R, Weissleder R, Nakakoshi T, Moore A, Tung CH Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide Bioconjug Chem. 2000;11:301-5 - PMID: 10821645 - DOI: 10.1021/bc990168d
Tung CH, Bredow S, Mahmood U, Weissleder R Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging Bioconjug Chem. 1999;10:892-6 - PMID: 10502358 - DOI: 10.1021/bc990052h
Josephson L, Tung CH, Moore A, Weissleder R High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates Bioconjug Chem. 1999;10:186-91 - PMID: 10077466 - DOI: 10.1021/bc980125h
Kircher MF, Weissleder R, Josephson L A dual fluorochrome probe for imaging proteases Bioconjug Chem. 2004;15:242-8 - PMID: 15025519 - DOI: 10.1021/bc034151d
Banerjee P, Reichardt W, Weissleder R, Bogdanov A Jr Novel hyperbranched dendron for gene transfer in vitro and in vivo. Bioconjug Chem. 2004;15(5):960-8 - PMID: 15366948 - DOI: 10.1021/bc0342128
Schellenberger EA, Sosnovik D, Weissleder R, Josephson L Magneto/Optical annexin v, a multimodal protein. Bioconjug Chem. 2004;15(5):1062-7 - PMID: 15366960 - DOI: 10.1021/bc049905i
Pham W, Choi Y, Weissleder R, Tung CH Developing a Peptide-Based Near-Infrared Molecular Probe for Protease Sensing. Bioconjug Chem. 2004;15(6):1403-1407 - PMID: 15546208 - DOI: 10.1021/bc049924s
Metelev V, Weissleder R, Bogdanov A Jr Synthesis and Properties of Fluorescent NF-kappaB-Recognizing Hairpin Oligodeoxyribonucleotide Decoys. Bioconjug Chem. 2004;15(6):1481-1487 - PMID: 15546218 - DOI: 10.1021/bc049916b
Tsourkas A, Shinde-Patil VR, Kelly KA, Patel P, Wolley A, Allport JR, Weissleder R. In Vivo Imaging of Activated Endothelium Using an Anti-VCAM-1 Magneto optical Probe Bioconjug Chem. 2005;(3):576-581 - PMID: 15898724 - DOI: 10.1021/bc050002e
Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L. Synthesis and Activity of C11-Modified Wortmannin Probes for P13 Kinase Bioconjug Chem. 2005;(3):669-675 - PMID: 15898736 - DOI: 10.1021/bc049714f
Reynolds F, Weissleder R, Josephson L. Protamine as an efficient membrane-translocating Peptide Bioconjug Chem. 2005;16(5):1240-5 - PMID: 16173804 - DOI: 10.1021/bc0501451
Hilderbrand SA, Kelly KA, Weissleder R, Tung CH. Monofunctional near-infrared fluorochromes for imaging applications Bioconjug Chem. 2005;16(5):1275-81 - PMID: 16173808 - DOI: 10.1021/bc0501799
Sun EY, Josephson L, Kelly KA, Weissleder R Development of nanoparticle libraries for biosensing. Bioconjug Chem. 2006;17(1):109-13 - PMID: 16417258 - DOI: 10.1021/bc050290e
Banerjee P, Weissleder R, Bogdanov A Linear Polyethyleneimine Grafted to a Hyperbranched Poly(ethylene glycol)-like Core: A Copolymer for Gene Delivery. Bioconjug Chem. 2006;17(1):125-31 - PMID: 16417260 - DOI: 10.1021/bc050083e
Galande A, Weissleder R, Tung CH. Fluorescence Probe with a pH-Sensitive Trigger Bioconjug Chem. 2006;17 (2):255-257 - PMID: 16536452 - DOI: 10.1021/bc050330e
Montet X, Weissleder R, Josephson L. Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas Bioconjug Chem. 2006;17(4):905-911 - PMID: 16848396 - DOI: 10.1021/bc060035+
Lai KS, Ho NH, Cheng JD, Tung CH Selective Fluorescence Probes for Dipeptidyl Peptidase Activity-Fibroblast Activation Protein and Dipeptidyl Peptidase IV. Bioconjug Chem. 2007;18(4):1246-50 - PMID: 17489551 - PMCID: PMC2562575 - DOI: 10.1021/bc0603586
Kim GY, Josephson L, Langer R, Cima MJ Magnetic Relaxation Switch Detection of Human Chorionic Gonadotrophin. Bioconjug Chem. 2007;18(6):2024-8 - PMID: 17892270 - DOI: 10.1021/bc070110w
Law B, Weissleder R, Tung CH Protease-Sensitive Fluorescent Nanofibers. Bioconjug Chem. 2007;(18) 6 ::1701-1704 - PMID: 17915958 - PMCID: PMC2528070 - DOI: 10.1021/bc070054z
Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L Fate of a Bioactive Fluorescent Wortmannin Derivative in Cells. Bioconjug Chem. 2007;19:130-137 - PMID: 17988080 - DOI: 10.1021/bc7002204
Hilderbrand SA, Kelly KA, Niedre M, Weissleder R Near Infrared Fluorescence-Based Bacteriophage Particles for Ratiometric pH Imaging. Bioconjug Chem. 2008;19(8):1635-9 - PMID: 18666791 - PMCID: PMC2705288 - DOI: 10.1021/bc800188p
Shao F, Weissleder R, Hilderbrand SA Monofunctional Carbocyanine Dyes for Bio- and Bioorthogonal Conjugation. Bioconjug Chem. 2008;19(12): :2487-2491 - PMID: 19053316 - PMCID: PMC2656649 - DOI: 10.1021/bc800417b
Devaraj N, Weissleder R, Hilderbrand S Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging. Bioconjug Chem. 2008;19(12):2297-2299 - PMID: 19053305 - PMCID: PMC2677645 - DOI: 10.1021/bc8004446
Garanger E, Weissleder R, Josephson L A Multifunctional Single-Attachment-Point Reagent for Controlled Protein Biotinylation. Bioconjug Chem. 2009;20(1):170-173 - PMID: 19072220 - PMCID: PMC2692913 - DOI: 10.1021/bc800392t
Devaraj NK*, Keliher EJ*, Thurber GM, Nahrendorf M, Weissleder R (18)F Labeled Nanoparticles for in Vivo PET-CT Imaging. Bioconjug Chem. 2009;20(2):397-401 - PMID: 19138113 - PMCID: PMC2644737 - DOI: 10.1021/bc8004649
McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA Multimodal Nanoagents for the Detection of Intravascular Thrombi. Bioconjug Chem. 2009;20(6):1251-5 - PMID: 19456115 - PMCID: PMC2733224 - DOI: 10.1021/bc9001163
Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L A Wortmannin-Cetuximab as a Double Drug. Bioconjug Chem. 2009;20 :2185-2189 - PMID: 19883074 - PMCID: PMC3386608 - DOI: 10.1021/bc900176a
Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY Binding Affinity and Kinetic Analysis of Targeted Small Molecule-Modified Nanoparticles Bioconjug Chem. 2010;21:14-19 - PMID: 20028085 - PMCID: PMC2902264 - DOI: 10.1021/bc900438a
Reiner T, Kohler RH, Liew CW, Hill JA, Gaglia J, Kulkarni RN, Weissleder R Near-Infrared Fluorescent Probe for Imaging of Pancreatic B Cells Bioconjug Chem. 2010;21:1362-1368 - PMID: 20583828 - PMCID: PMC2912453 - DOI: 10.1021/bc100184w
Marecos E, Weissleder R, Bogdanov A Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model. Bioconjug Chem. 1998;9(2):184-91 - PMID: 9548533 - DOI: 10.1021/bc970146w
Shen TT, Bogdanov A, Bogdanova A, Poss K, Brady TJ, Weissleder R Magnetically labeled secretin retains receptor affinity to pancreas acinar cells. Bioconjug Chem. 1996;7(3):311-6 - PMID: 8816953 - DOI: 10.1021/bc960003u
Bogdanov AA, Martin C, Bogdanova AV, Brady TJ, Weissleder R An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties. Bioconjug Chem. 1996;7(1):144-9 - PMID: 8742003 - DOI: 10.1021/bc950089b
Zeglis BM, Mohindra P, Weissmann GI, Divilov V, Hilderbrand SA, Weissleder R, Lewis JS A Modular Strategy for the Construction of Radiometallated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels-Alder Click Chemistry. Bioconjug Chem. 2011;22(10):2048-59 - PMID: 21877749 - PMCID: PMC3197258 - DOI: 10.1021/bc200288d
Karver M, Weissleder R, Hilderbrand SA Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation. Bioconjug Chem. 2011;22(11):2263-2270 - PMID: 21950520 - PMCID: PMC3254257 - DOI: 10.1021/bc200295y
Keliher E, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet M, Weissleder R 89Zr Labeled Dextran Nanoparticles Enable in vivo Macrophage Imaging. Bioconjug Chem. 2011;22(12):2383-9 - PMID: 22035047 - PMCID: PMC3244512 - DOI: 10.1021/bc200405d
Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance. Bioconjug Chem. 2011;22(12):2390-4 - PMID: 22043803 - PMCID: PMC3263317 - DOI: 10.1021/bc200490r
Lu X, Agasti SS, Vinegoni C, Waterman P, Depinho R, Weissleder R Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators. Bioconjug Chem. 2012;23(9):1945-51 - PMID: 22917215 - PMCID: PMC3775343 - DOI: 10.1021/bc300319c
Clardy SM, Keliher EJ, Mohan JF, Sebas M, Benoist C, Mathis D, Weissleder R Fluorescent Exendin-4 Derivatives for Pancreatic β-Cell Analysis. Bioconjug Chem. 2013;25(1):171-177 - PMID: 24328216 - PMCID: PMC4016126 - DOI: 10.1021/bc4005014
Courtis AM, Santos SA, Guan Y, Hendricks JA, Ghosh B, Szantai-Kis DM, Reis SA, Shah JV, Mazitschek R Monoalkoxy BODIPYs - A Fluorophore Class for Bioimaging. Bioconjug Chem. 2014;25(6):1043-51 - PMID: 24797834 - PMCID: PMC4215867 - DOI: 10.1021/bc400575w
Sprachman M, Laughney A, Kohler R, Weissleder R In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor. Bioconjug Chem. 2014;25(6):1137-42 - PMID: 24806886 - PMCID: PMC4098115 - DOI: 10.1021/bc500154c
Brand C, Abdel-Atti D, Zhang Y, Carlin S, Clardy SM, Keliher EJ, Weber WA, Lewis JS, Reiner T In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent. Bioconjug Chem. 2014;25(7):1323-30 - PMID: 24856928 - PMCID: PMC4215873 - DOI: 10.1021/bc500178d
Giedt RJ, Sprachman M, Yang K, Weissleder R Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates. Bioconjug Chem. 2014;25(11):2081-2085 - PMID: 25333750 - PMCID: PMC4240345 - DOI: 10.1021/bc500433k
Kim E, Yang K, Kohler R, Dubach JM, Mikula H, Weissleder R Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression. Bioconjug Chem. 2015;26(8):1513-1518 - PMID: 26017814 - PMCID: PMC4772718 - DOI: 10.1021/acs.bioconjchem.5b00152
Park YI, Im H, Weissleder R, Lee H Nanostar clustering improves the sensitivity of plasmonic assays. Bioconjug Chem. 2015;26(8):1470-1474 - PMID: 26102604 - PMCID: PMC5292976 - DOI: 10.1021/acs.bioconjchem.5b00343
Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies. Bioconjug Chem. 2015;27(1):257-63 - PMID: 26684717 - PMCID: PMC4858350 - DOI: 10.1021/acs.bioconjchem.5b00630
Piccirillo G M, Binda E, Fiocco R, Vescovi L, Shah K Brain cancer stem cells. J Mol Med. 2009;87(11):1087-95 - PMID: 19784875 - DOI: 10.1007/s00109-009-0535-3
Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells. J Gen Physiol. 2004;124(4):395-407 - PMID: 15452200 - PMCID: PMC2233909 - DOI: 10.1085/jgp.200409120
Li C, Breton S, Morrison R, Cannon CL, Emma F, Sanchez-Olea R, Bear C, Strange K Recombinant pICln forms highly cation-selective channels when reconstituted into artificial and biological membranes. J Gen Physiol. 1998;112(6):727-36 - PMID: 9834142 - PMCID: PMC2229450 - DOI: 10.1085/jgp.112.6.727
Xu Y, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis. J Lipid Res. 2014;56(2):266-76 - PMID: 25528754 - PMCID: PMC4306681 - DOI: 10.1194/jlr.M053017
Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH Caveolin-1 Ablation Reduces the Adverse Cardiovascular Effects of N-{omega}-Nitro-L-Arginine Methyl Ester and Angiotensin II. Endocrinology. 2010;151(3):1236-46 - PMID: 20097717 - PMCID: PMC2840694 - DOI: 10.1210/en.2009-0514
Liu Z, Segawa H, Aydin C, Reyes M, Erben RG, Weinstein LS, Chen M, Marshansky V, Frohlich LF, Bastepe M Transgenic Overexpression of the Extra-Large Gs{alpha} Variant XL{alpha}s Enhances Gs{alpha}-Mediated Responses in the Mouse Renal Proximal Tubule in Vivo. Endocrinology. 2011;152(4):1222-33 - PMID: 21303955 - PMCID: PMC3060637 - DOI: 10.1210/en.2010-1034
Chen S, Webber MJ, Vilardaga JP, Khatri A, Brown D, Ausiello DA, Lin HY, Bouley R Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand. Endocrinology. 2011;152(10):3893-904 - PMID: 21828182 - PMCID: PMC3176653 - DOI: 10.1210/en.2011-1049
Xia Y, Sidis Y, Mukherjee A, Samad TA, Brenner G, Woolf CJ, Lin HY, Schneyer A Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis. Endocrinology. 2005;146(8):3614-21 - PMID: 15890774 - PMCID: PMC1351303 - DOI: 10.1210/en.2004-1676
Jun HJ, Roy J, Smith TB, Wood LB, Lane K, Woolfenden S, Punko D, Bronson RT, Haigis KM, Breton S, Charest A ROS1 Signaling Regulates Epithelial Differentiation in the Epididymis. Endocrinology. 2014;155(9):3661-73 - PMID: 24971615 - PMCID: PMC4138574 - DOI: 10.1210/en.2014-1341
Hilderbrand S, Lippard S Cobalt chemistry with mixed aminotroponiminate salicylaldiminate ligands: synthesis, characterization, and nitric oxide reactivity. Inorg Chem. 2004;43:4674-82 - PMID: 15257596 - DOI: 10.1021/ic049776h
Hilderbrand S, Lippard S Nitric oxide reactivity of fluorophore coordinated carboxylate-bridged diiron(II) and dicobalt(II) complexes. Inorg Chem. 2004;43:5294-301 - PMID: 15310207 - DOI: 10.1021/ic049649l
Nolan E, Burdette S, Harvey J, Hilderbrand S, Lippard S Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorg Chem. 2004;43:2624-35 - PMID: 15074981 - DOI: 10.1021/ic035158+
Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecol Oncol. 2009;112(3):616-22 - PMID: 19135233 - PMCID: PMC2664404 - DOI: 10.1016/j.ygyno.2008.11.018
Brown D, Breton S, Ausiello DA, Marshansky V Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology. Traffic. 2009;10(3):275-84 - PMID: 19170982 - PMCID: PMC2896909 - DOI: 10.1111/j.1600-0854.2008.00867.x
Beaulieu V, Da Silva N, Pastor-Soler N, Brown CR, Smith PJ, Brown D, Breton S Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling. J Biol Chem. 2005;280(9):8452-63 - PMID: 15591047 - DOI: 10.1074/jbc.M412750200
Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D Heat shock protein 70 interacts with aquaporin-2 (AQP2) and regulates its trafficking. J Biol Chem. 2007;282(39):28721-32 - PMID: 17636261 - DOI: 10.1074/jbc.M611101200
Pietrement C, Da Silva N, Silberstein C, James M, Marsolais M, Van Hoek A, Brown D, Pastor-Soler N, Ameen N, Laprade R, Ramesh V, Breton S Role of NHERF1, CFTR and cAMP in the regulation of aquaporin 9 J Biol Chem. 2008;283:2986-96 - PMID: 18055461 - DOI: 10.1074/jbc.M704678200
Johnson E, Lee Y, Sander T, Rabkin E, Schoen F, Kaushal S, Bischoff J NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells. J Biol Chem. 2003;278:1686-92 - PMID: 12427739 - PMCID: PMC2813494 - DOI: 10.1074/jbc.M210250200
Shah K, Vervoort J, de Vries S Role of threonines in the Arabidopsis thaliana somatic embryogenesis receptor kinase 1 activation loop in phosphorylation. J Biol Chem. 2001;276(44):41263-9 - PMID: 11509554 - DOI: 10.1074/jbc.M102381200
Xia Y, Yu P, Sidis Y, Beppu H, Bloch K, Schneyer A, Lin H Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem. 2007;282(25):18129-40 - PMID: 17472960 - DOI: 10.1074/jbc.M701679200
Babitt J, Zhang Y, Samad T, Xia Y, Tang J, Campagna J, Schneyer A, Woolf C, Lin HY Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem. 2005;280(33):29820-7 - PMID: 15975920 - DOI: 10.1074/jbc.M503511200
del Re E, Sidis Y, Fabrizio D, Lin HY, Schneyer A Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system. J Biol Chem. 2004;279(51):53126-35 - PMID: 15475360 - DOI: 10.1074/jbc.M408090200
del Re E, Babitt J, Pirani A, Schneyer A, Lin HY In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2. J Biol Chem. 2004;279(21):22765-72 - PMID: 14996829 - DOI: 10.1074/jbc.M401350200
Hasler U, Nunes P, Bouley R, Lu HA, Matsuzaki T, Brown D Acute hypertonicity alters aquaporin-2 trafficking and induces a MAP kinase-dependent accumulation at the plasma membrane of renal epithelial cells. J Biol Chem. 2008;283(39):26643-61 - PMID: 18664568 - PMCID: PMC2546545 - DOI: 10.1074/jbc.M801071200
Schuetz A, Min J, Allali-Hassani A, Schapira M, Shuen M, Loppnau P, Mazitschek R, Kwiatkowski N, Lewis T, Maglathin R, McLean T, Bochkarev A, Plotnikov A, Vedadi M, Arrowsmith C Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. J Biol Chem. 2008;283(17):11355-63 - PMID: 18285338 - PMCID: PMC2431080 - DOI: 10.1074/jbc.M707362200
Kawada J, Zou P, Mazitschek R, Bradner JE, Cohen JI Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis. J Biol Chem. 2009;284(25):17102-9 - PMID: 19386607 - PMCID: PMC2719348 - DOI: 10.1074/jbc.M809090200
Tharp A, Laha M, Panizzi P, Thompson M, Fuentes-Prior P, Bock P Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and Kringle 5 of the substrate. J Biol Chem. 2009;284(29):19511-21 - PMID: 19473980 - PMCID: PMC2740577 - DOI: 10.1074/jbc.M109.005512
Wiles KG, Panizzi P, Kroh HK, Bock PE Skizzle is a novel plasminogen and plasmin binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generation. J Biol Chem. 2010;285(27):21153-64 - PMID: 20435890 - PMCID: PMC2898333 - DOI: 10.1074/jbc.M110.107730
Maenz DD, Chenu C, Breton S, Berteloot A pH-dependent heterogeneity of acidic amino acid transport in rabbit jejunal brush border membrane vesicles. J Biol Chem. 1992;267(3):1510-6 - PMID: 1346136
Breton S, Wiederhold T, Marshansky V, Nsumu NN, Ramesh V, Brown D The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells. J Biol Chem. 2000;275(24):18219-24 - PMID: 10748165 - DOI: 10.1074/jbc.M909857199
Pastor-Soler N, Beaulieu V, Litvin TN, Da Silva N, Chen Y, Brown D, Buck J, Levin LR, Breton S Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling. J Biol Chem. 2003;278(49):49523-9 - PMID: 14512417 - PMCID: PMC3652382 - DOI: 10.1074/jbc.M309543200
van Balkom BW, van Raak M, Breton S, Pastor-Soler N, Bouley R, van der Sluijs P, Brown D, Deen PM Hypertonicity is involved in redirecting the aquaporin-2 water channel into the basolateral, instead of the apical, plasma membrane of renal epithelial cells. J Biol Chem. 2002;278(2):1101-7 - PMID: 12374804 - DOI: 10.1074/jbc.M207339200
Li Y, Si R, Feng Y, Chen HH, Zou L, Wang E, Zhang M, Warren HS, Sosnovik DE, Chao W Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4. J Biol Chem. 2011;286(36):31308-19 - PMID: 21775438 - PMCID: PMC3173057 - DOI: 10.1074/jbc.M111.246124
Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem. 2005;280(14):14122-9 - PMID: 15671031 - DOI: 10.1074/jbc.M410034200
Maranda B, Brown D, Bourgoin S, Casanova JE, Vinay P, Ausiello DA, Marshansky V Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomes. J Biol Chem. 2001;276(21):18540-50 - PMID: 11278939 - DOI: 10.1074/jbc.M011577200
Hosokawa H, Dip PV, Merkulova M, Bakulina A, Zhuang Z, Khatri A, Jian X, Keating SM, Bueler SA, Rubinstein JL, Randazzo PA, Ausiello DA, Gruber G, Marshansky V The N-terminus of a-Subunit Isoforms is Involved in Signaling between V-ATPase and Cytohesin-2. J Biol Chem. 2013;288(8):5896-913 - PMID: 23288846 - PMCID: PMC3581410 - DOI: 10.1074/jbc.M112.409169
Feinstein TN, Yui N, Webber MJ, Wehbi VL, Stevenson HP, King JD, Hallows KR, Brown D, Bouley R, Vilardaga JP Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin. J Biol Chem. 2013;288(39):27849-60 - PMID: 23935101 - PMCID: PMC3784700 - DOI: 10.1074/jbc.M112.445098
Zumbrennen-Bullough K, Wu Q, Core AB, Canali S, Chen W, Theurl I, Meynard D, Babitt JL MicroRNA-130a is upregulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription. J Biol Chem. 2014;289(34):23796-808 - PMID: 25002578 - PMCID: PMC4156078 - DOI: 10.1074/jbc.M114.577387
Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein. J Biol Chem. 2011;286(47):40443-51 - PMID: 21956108 - PMCID: PMC3220463 - DOI: 10.1074/jbc.M111.280495
Otu HH*, Naxerova K*, Ho K, Can H, Nesbitt N, Libermann TA, Karp SJ Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns. J Biol Chem. 2007;282(15):11197-204 - PMID: 17227769 - DOI: 10.1074/jbc.M608441200
Chen S, Reynolds F, Yu L, Weissleder R, Josephson L A screening paradigm for the design of improved polymer-coated superparamagnetic iron oxide nanoparticles J Mater Chem. 2009;19:6387-6392
Zimmer C, Wright SC, Engelhardt RT, Johnson GA, Kramm C, Breakefield XO, Weissleder R Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface. Exp Neurol. 1997;143(1):61-9 - PMID: 9000446 - DOI: 10.1006/exnr.1996.6350
Enochs WS, Schaffer B, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R MR imaging of slow axonal transport in vivo. Exp Neurol. 1993;123(2):235-42 - PMID: 8405287 - DOI: 10.1006/exnr.1993.1156
Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014;133(11):1369-82 - PMID: 25062868 - PMCID: PMC4185241 - DOI: 10.1007/s00439-014-1466-9
Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport. Mol Biol Cell. 2000;11(9):3155-68 - PMID: 10982407 - PMCID: PMC14982 - DOI: 10.1091/mbc.11.9.3155
Cabrero JR, Serrador JM, Barreiro O, Mittelbrunn M, Naranjo-Suárez S, Martín-Cófreces N, Vicente-Manzanares M, Mazitschek R, Bradner JE, Avila J, Valenzuela-Fernández A, Sánchez-Madrid F Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell. 2006;17(8):3435-45 - PMID: 16738306 - PMCID: PMC1525231 - DOI: 10.1091/mbc.E06-01-0008
Guan Y, Meurer M, Raghavan S, Rebane A, Lindquist JR, Santos S, Kats I, Davidson MW, Mazitschek R, Hughes TE, Drobizhev M, Knop M, Shah JV Live Cell Multi-Photon Fluorescence Correlation Spectroscopy with an Improved Large Stokes Shift Fluorescent Protein. Mol Biol Cell. 2015;26(11):2054-66 - PMID: 25877871 - PMCID: PMC4472016 - DOI: 10.1091/mbc.E14-10-1473
Lee S, Vinegoni C, Sebas M, Weissleder R Automated motion artifact removal for intravital microscopy, without a priori information. Sci Rep. 2014;4:4507 - PMID: 24676021 - PMCID: PMC3968488 - DOI: 10.1038/srep04507
Turetsky A, Kim E, Kohler RH, Miller MA, Weissleder R Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor. Sci Rep. 2014;4:4782 - PMID: 24759210 - PMCID: PMC3998017 - DOI: 10.1038/srep04782
Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R Single cell resolution in vivo imaging of DNA damage following PARP inhibition Sci Rep. 2015;5:10129 - PMID: 25984718 - PMCID: PMC4434991 - DOI: 10.1038/srep10129
Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, Hanna RN, Wu R, Swirski FK, Geissmann F, Hedrick CC The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus. Sci Rep. 2015;5:10055 - PMID: 26091486 - PMCID: PMC4473761 - DOI: 10.1038/srep10055
Clardy SM, James F. Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R Rapid, high efficiency isolation of pancreatic ß-cells Sci Rep. 2015;5:13681 - PMID: 26330153 - PMCID: PMC4557033 - DOI: 10.1038/srep13681
Merkulova M, Păunescu TG, Azroyan A, Marshansky V, Breton S, Brown D Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation. Sci Rep. 2015;5:14827 - PMID: 26442671 - PMCID: PMC4595830 - DOI: 10.1038/srep14827
Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R, Azzi J, Nicolay K, Tannous BA Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging. Sci Rep. 2015;5:17220 - PMID: 26610702 - PMCID: PMC4661695 - DOI: 10.1038/srep17220
Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain. Sci Rep. 2015;5:15150 - PMID: 26477568 - PMCID: PMC4609913 - DOI: 10.1038/srep15150
Merkulova M, Bakulina A, Thaker YR, Gruber G, Marshansky V Specific motifs of the V-ATPase a2-subunit isoform interact with catalytic and regulatory domains of ARNO. Biochim Biophys Acta. 2010;1797(8):1398-1409 - PMID: 20153292 - DOI: 10.1016/j.bbabio.2010.02.009
Moore A, Basilion JP, Chiocca EA, Weissleder R Measuring transferrin receptor gene expression by NMR imaging. Biochim Biophys Acta. 1998;1402(3):239-49 - PMID: 9606982 - DOI: 10.1016/s0167-4889(98)00002-0
Bogdanov A, Simonova M, Weissleder R Design of metal-binding green fluorescent protein variants. Biochim Biophys Acta. 1998;1397(1):56-64 - PMID: 9545533 - DOI: 10.1016/s0167-4781(97)00221-2
Bogdanov AA, Martin C, Weissleder R, Brady TJ Trapping of dextran-coated colloids in liposomes by transient binding to aminophospholipid: preparation of ferrosomes. Biochim Biophys Acta. 1994;1193(1):212-8 - PMID: 7518693 - DOI: 10.1016/0005-2736(94)90350-6
Da Silva N, Pietrement C, Brown D, Breton S Segmental and cellular expression of aquaporins in the male excurrent duct. Biochim Biophys Acta. 2006;1758(8):1025-33 - PMID: 16935257 - DOI: 10.1016/j.bbamem.2006.06.026
Marshansky V, Rubinstein JL, Grüber G Eukaryotic V-ATPase: Novel Structural Findings and Functional Insights. Biochim Biophys Acta. 2014;1837(6):857-879 - PMID: 24508215 - DOI: 10.1016/j.bbabio.2014.01.018
Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration. J Leukocyte biol. 2006;81(3):748-56 - PMID: 17178915 - DOI: 10.1189/jlb.1105664
Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF A colorimetric high throughput screen for the detection of heme crystallization inhibitors. Antimicrob Agents Chemother. 2009;53(6):2564-8 - PMID: 19307367 - PMCID: PMC2687197 - DOI: 10.1128/AAC.01466-08
Weissleder R, Poss K, Wilkinson R, Zhou C, Bogdanov A Quantitation of slow drug release from an implantable and degradable gentamicin conjugate by in vivo magnetic resonance imaging. Antimicrob Agents Chemother. 1995;39(4):839-45 - PMID: 7785981 - PMCID: PMC162639 - DOI: 10.1128/aac.39.4.839
Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman BI, Angulo-Barturen I, Jimenez-Diaz MB, Magan N, Gomez V, Ferrer S, Santos Marti Aminoindoles: a Novel Scaffold with Potent Activity against Plasmodium falciparum. Antimicrob Agents Chemother. 2011;55(6):2612-22 - PMID: 21422215 - PMCID: PMC3101419 - DOI: 10.1128/AAC.01714-10
Păunescu TG, Shum WW, Huynh C, Lechner L, Goetze B, Brown D, Breton S High-resolution helium ion microscopy of epididymal epithelial cells and their interaction with spermatozoa. Mol Hum Reprod. 2014;20(10):929-37 - PMID: 25015675 - PMCID: PMC4172170 - DOI: 10.1093/molehr/gau052
Shi S, Hoogaars WM, de Gorter DJ, van Heiningen SH, Lin HY, Hong CC, Kemaladewi DU, Aartsma-Rus A, Ten Dijke P, 't Hoen PA BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model. Neurobiol Dis. 2010;41(2):353-60 - PMID: 20940052 - PMCID: PMC3674857 - DOI: 10.1016/j.nbd.2010.10.003
Setoguchi S, Higgins JM, Mogun H, Mootha VK, Avorn J Propranolol and the risk of hospitalized myopathy: Translating chemical genomics findings into population-level hypotheses. Am Heart J. 2010;159(3):428-433 - PMID: 20211305 - DOI: 10.1016/j.ahj.2009.12.008
Huang X, Im H, Lee D, Kim H, Choi Y Ferrocene Functionalized Single-Walled Carbon Nanotube Bundles. Hybrid Interdigitated Construction Film for l-Glutamate Detection J Phys Chem C. 2007;111(3):1200-1206
Cortez-Retamozo V, Etzrodt M, Pittet MJ Regulation of Macrophage and Dendritic Cell Responses by Their Lineage Precursors. J Innate Immunity. 2012;4(5-6):411-23 - PMID: 22433183 - PMCID: PMC3498093 - DOI: 10.1159/000335733
Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE Noninvasive imaging of apoptosis in cardiovascular disease. Heart Fail Rev. 2008;13(2)::163-173 - PMID: 18074226 - PMCID: PMC2597223 - DOI: 10.1007/s10741-007-9068-4
Higgins JM, Eddington DT, Bhatia SN, Mahadevan L Statistical dynamics of flowing red blood cells by morphological image processing. PLoS Comput Biol. 2009;5(2):e1000288 - PMID: 19214200 - PMCID: PMC2631282 - DOI: 10.1371/journal.pcbi.1000288
Malka R, Delgado FF, Manalis SR, Higgins JM In Vivo Volume and Hemoglobin Dynamics of Human Red Blood Cells. PLoS Comput Biol. 2014;10(10):e1003839 - PMID: 25299941 - PMCID: PMC4191880 - DOI: 10.1371/journal.pcbi.1003839
Miller M, Hafner M, Sontag E, Davidsohn N, Subramanian S, Purnick PE, Lauffenburger D, Weiss R Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity. PLoS Comput Biol. 2012;8(7):e1002579 - PMID: 22829755 - PMCID: PMC3400602 - DOI: 10.1371/journal.pcbi.1002579
Tung CH, Quinti L, Jaffer F, Weissleder R A Branched Fluorescent Peptide Probe for Imaging of Activated Platelets Mol Pharmacol. 2005;2:92-95 - PMID: 15804182 - DOI: 10.1021/mp0499048
Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV 8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells. Mol Pharmacol. 2007;72(5):1137-45 - PMID: 17675586 - DOI: 10.1124/mol.107.038117
Kelly K*, Shaw SY*, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R. Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries. Integr Biol (Camb). 2009;1(4):311-317 - PMID: 20023731 - PMCID: PMC2748356 - DOI: 10.1039/b821775k
Taqueti VR, Jaffer FA High-resolution molecular imaging via intravital microscopy: illuminating vascular biology in vivo. Integr Biol (Camb). 2013;5(2):278-90 - PMID: 23135362 - PMCID: PMC3558556 - DOI: 10.1039/c2ib20194a
Miller MA, Barkal L, Jeng K, Herrlich A, Moss M, Griffith LG, Lauffenburger DA Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities. Integr Biol (Camb). 2010;3(4):422-38 - PMID: 21180771 - PMCID: PMC3173501 - DOI: 10.1039/c0ib00083c
Ruan YC, Shum WW, Belleannée C, Da Silva N, Breton S ATP secretion in the male reproductive tract: essential role of CFTR. J Physiol. 2012;590(Pt 17):4209-22 - PMID: 22711960 - PMCID: PMC3473280 - DOI: 10.1113/jphysiol.2012.230581
Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model. ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v
McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity. ACS Chem Biol. 2012;7(9):1520-8 - PMID: 22724584 - DOI: 10.1021/cb300235m
Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules. ACS Chem Biol. 2013;8(12):2724-33 - PMID: 24168452 - PMCID: PMC3951132 - DOI: 10.1021/cb400352d
McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S Correction to Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity. ACS Chem Biol. 2012;9(4):1061 - PMID: 22724584 - DOI: 10.1021/cb300235m
Iaconelli J, Huang JH, Berkovitch SS, Chattopadhyay S, Mazitschek R, Schreiber SL, Haggarty SJ, Karmacharya R HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells. ACS Chem Biol. 2015;10(3):883-90 - PMID: 25546293 - PMCID: PMC4372110 - DOI: 10.1021/cb500838r
Pittet MJ, Nahrendorf M, Swirski FK The journey from stem cell to macrophage. Ann N Y Acad Sci. 2014;1319(1):1-18 - PMID: 24673186 - PMCID: PMC4074243 - DOI: 10.1111/nyas.12393
Bhaumik J, Weissleder R, McCarthy JR Synthesis and Photophysical Properties of Sulfonamidophenyl Porphyrins as Models for Activatable Photosensitizers. J Org Chem. 2009;74(16):5894-901 - PMID: 19610602 - PMCID: PMC2888918 - DOI: 10.1021/jo900832y
Brueckner C, Ogikubo J, McCarthy JR, Akhigbe J, Hyland MA, Daddario P, Worlinsky JL, Zeller M, Engle JT, Ziegler CJ, Ranaghan MJ, Sandberg MN, Birge RR meso-Arylporpholactones and their Reduction Products. J Org Chem. 2012;77(15):6480-94 - PMID: 22734444 - PMCID: PMC3411881 - DOI: 10.1021/jo300963m
Bogdanov AA, Lin CP, Kang HW Optical imaging of the adoptive transfer of human endothelial cells in mice using anti-human CD31 monoclonal antibody. Pharmacol Res. 2007;24:1186-92 - PMID: 17373582 - PMCID: PMC2795329 - DOI: 10.1007/s11095-006-9219-7
Roedl JB, Harisinghani MG, Colen RR, Fischman AJ, Blake MA, Mathisen DJ, Mueller PR Assessment of treatment response and recurrence in esophageal carcinoma based on tumor length and standardized uptake value on positron emission tomography-computed tomography. Ann Thorac Surg. 2008;86:1131-8 - PMID: 18805147 - DOI: 10.1016/j.athoracsur.2008.05.019
Kim KM, Cambria RP, Isselbacher EM, Baker JN, LaMuraglia GM, Stone JR, MacGillivray TE Contemporary Surgical Approaches and Outcomes in Adults With Kommerell Diverticulum. Ann Thorac Surg. 2014;98(4):1347-1354 - PMID: 25134861 - DOI: 10.1016/j.athoracsur.2014.05.045
Heng E, Stone JR, Kim JB, Lee H, MacGillivray TE, Sundt TM Comparative Histology of Aortic Dilatation Associated With Bileaflet Versus Trileaflet Aortic Valves. Ann Thorac Surg. 2015;100(6):2095-2101 - PMID: 26338050 - DOI: 10.1016/j.athoracsur.2015.05.105
Bogdanov A Jr, Tung CH, Bredow S, Weissleder R DNA binding chelates for nonviral gene delivery imaging Gene Ther. 2001;8:515-22 - PMID: 11319618 - DOI: 10.1038/sj.gt.3301410
Schellingerhout D, Rainov NG, Breakefield XO, Weissleder R Quantitation of HSV mass distribution in a rodent brain tumor model Gene Ther. 2000;7:1648-55 - PMID: 11083473 - DOI: 10.1038/sj.gt.3301272
Shah K, Jacobs A, Breakefield XO, Weissleder R Molecular imaging of gene therapy for cancer Gene Ther. 2004;11(15):1175-87 - PMID: 15141158 - DOI: 10.1038/sj.gt.3302278
Pai SI, Lin YY, Macaes B, Meneshian A, Hung CF, Wu TC Prospects of RNA interference therapy for cancer. Gene Ther. 2006;13(6):464-77 - PMID: 16341059 - DOI: 10.1038/sj.gt.3302694
Wu A, Zeng Q, Kang TH, Peng S, Roosinovich E, Pai SI, Hung CF Innovative DNA vaccine for human papillomavirus (HPV)-associated head and neck cancer. Gene Ther. 2010;18(3):304-12 - PMID: 20981112 - PMCID: PMC3032008 - DOI: 10.1038/gt.2010.151
Kang TH, Chung JY, Monie A, Pai SI, Hung CF, Wu TC Enhancing DNA vaccine potency by co-administration of xenogenic MHC class-I DNA. Gene Ther. 2009;17(4):531-40 - PMID: 19940864 - PMCID: PMC2851845 - DOI: 10.1038/gt.2009.152
Kim JW, Hung CF, Juang J, He L, Kim TW, Armstrong DK, Pai SI, Chen PJ, Lin CT, Boyd DA, Wu TC Comparison of HPV DNA vaccines employing intracellular targeting strategies. Gene Ther. 2004;11(12):1011-8 - PMID: 14985791 - DOI: 10.1038/sj.gt.3302252
Wang TL, Ling M, Shih IM, Pham T, Pai SI, Lu Z, Kurman RJ, Pardoll DM, Wu TC Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity. Gene Ther. 2000;7(9):726-33 - PMID: 10822298 - DOI: 10.1038/sj.gt.3301160
Michot C, Le Goff C, Mahaut C, Afenjar A, Brooks AS, Campeau PM, Destree A, Di Rocco M, Donnai D, Hennekam R, Heron D, Jacquemont S, Kannu P, Lin AE, Manouvrier-Hanu S, Mansour S, Marlin S, McGowan R, Murphy H, Raas-Rothschild A, Rio M, Simon M, Stolte-Dijkstra I, Stone JR, Sznajer Y, Tolmie J, Touraine R, van den Ende J, Van der Aa N, van Essen T, Verloes A, Munnich A, Cormier-Daire V Myhre and LAPS syndromes: clinical and molecular review of 32 patients. Eur J Hum Genet. 2014;22(11):1272-7 - PMID: 24424121 - PMCID: PMC4200423 - DOI: 10.1038/ejhg.2013.288
Chen WT, Mahmood U, Weissleder R, Tung CH Arthritis imaging using a near-infrared fluorescence folate-targeted probe Arthritis Res Ther. 2005;7:R310-R317 - PMID: 15743478 - PMCID: PMC1065321 - DOI: 10.1186/ar1483
Rao SM, Auger JL, Gaillard P, Weissleder R, Wada E, Torres R, Kojima M, Benoist C, Mathis D, Binstadt BA The neuropeptide neuromedin U promotes autoantibody-mediated arthritis. Arthritis Res Ther. 2012;14(1):R29 - PMID: 22314006 - PMCID: PMC3392824 - DOI: 10.1186/ar3732
Bhatia RS, Kumar V, Picard MH, Weiner RB Comparison of the 2008 and 2011 appropriate use criteria for stress echocardiography. J Am Soc Echocardiogr. 2013;26(4):339-43 - PMID: 23313389 - DOI: 10.1016/j.echo.2012.12.001
Pang Y, Tsigkou O, Spencer JA, Lin CP, Neville C, Grottkau B Analyzing Structure and Function of Vascularization in Engineered Bone Tissue by Video-rate Intravital Microscopy and 3D Image Processing. Tissue Eng Part C Methods. 2015;21(10):1025-1031 - PMID: 25962617 - PMCID: PMC4593976 - DOI: 10.1089/ten.TEC.2015.0091
Graves EE, Weissleder R, Ntziachristos V Fluorescence molecular imaging of small animal tumor models. Curr Mol Med. 2004;4(4):419-30 - PMID: 15354872 - DOI: 10.2174/1566524043360555
Russo LM, Brown D, Lin HY The soluble transforming growth factor-beta receptor: Advantages and applications. Int J Biochem Cell B. 2008;41(3):472-6 - PMID: 18339576 - DOI: 10.1016/j.biocel.2008.01.026
Robbins C, Dawe D, Goncharova S, Pouladi M, Drannik A, Swirski F, Cox G, Stampfli M Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness. Am J Respir Cell Mol Biol. 2004;30(2):202-11 - PMID: 12920055 - DOI: 10.1165/rcmb.2003-0259OC
Pouladi M, Robbins C, Swirski F, Cundall M, McKenzie A, Jordana M, Shapiro S, Stampfli M Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice. Am J Respir Cell Mol Biol. 2004;30(1):84-90 - PMID: 12842850 - DOI: 10.1165/rcmb.2003-0051OC
Gajewska B, Swirski F, Alvarez D, Ritz S, Goncharova S, Cundall M, Snider D, Coyle A, Gutierrez-Ramos J, Stampfli M, Jordana M Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation. Am J Respir Cell Mol Biol. 2001;25:326-34 - PMID: 11588010 - DOI: 10.1165/ajrcmb.25.3.4482
Kim JK, Vinarsky V, Wain JC, Zhao R, Jung K, Choi J, Lam A, Pardo-Saganta A, Breton S, Rajagopal J, Yun SH In vivo imaging of tracheal epithelial cells in mice during airway regeneration. Am J Respir Cell Mol Biol. 2012;47(6):864-8 - PMID: 22984086 - PMCID: PMC3547097 - DOI: 10.1165/rcmb.2012-0164OC
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W, Barker DD, Mazitschek R, Schreiber SL, Tsai LH, Haggarty SJ Crebinostat: A Novel cognitive enhancer that inhibits Histone Deacetylase activity and Modulates Chromatin-mediated Neuroplasticity. Neuropharmacology. 2012;64(1):81-96 - PMID: 22771460 - PMCID: PMC3447535 - DOI: 10.1016/j.neuropharm.2012.06.043
Lameijer MA, Tang J, Nahrendorf M, Beelen RH, Mulder WJ Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease. Expert Rev Mol Diagn. 2013;13(6):567-80 - PMID: 23895127 - PMCID: PMC4110962 - DOI: 10.1586/14737159.2013.819216
Im H, Shao H, Weissleder R, Castro CM, Lee H Nano-plasmonic exosome diagnostics. Expert Rev Mol Diagn. 2015;15(6):725-33 - PMID: 25936957 - PMCID: PMC4675626 - DOI: 10.1586/14737159.2015.1041378
Lasser T, Ntziachristos V Optimization of 360 degrees projection fluorescence molecular tomography. Med Image Anal. 2007;11(4):389-99 - PMID: 17524701 - DOI: 10.1016/j.media.2007.04.003
Nahrendorf M, Hiller K, Hu K, Ertl G, Haase A, Bauer W Cardiac magnetic resonance imaging in small animal models of human heart failure. Med Image Anal. 2003;7(3):369-75 - PMID: 12946475 - DOI: 10.1016/s1361-8415(03)00011-2
Paranya G, Vineberg S, Dvorin E, Kaushal S, Roth S, Rabkin E, Schoen F, Bischoff J Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro. Am J Pathol. 2001;159:1335-43 - PMID: 11583961 - PMCID: PMC1850524 - DOI: 10.1016/s0002-9440(10)62520-5
Panchenko MP, Siddiquee Z, Dombkowski DM, Alekseyev YO, Lenburg ME, Walker JD, Macgillivray TE, Preffer FI, Stone JR Protein Kinase CK1{alpha}LS Promotes Vascular Cell Proliferation and Intimal Hyperplasia. Am J Pathol. 2010;177(3):1562-72 - PMID: 20696773 - PMCID: PMC2928985 - DOI: 10.2353/ajpath.2010.100327
Muldoon LL, Nilaver G, Kroll RA, Pagel MA, Breakefield XO, Chiocca EA, Davidson BL, Weissleder R, Neuwelt EA Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Am J Pathol. 1995;147(6):1840-51 - PMID: 7495307 - PMCID: PMC1869962
Sales VL, Mettler BA, Engelmayr GC, Aikawa E, Bischoff J, Martin DP, Exarhopoulos A, Moses M, Schoen FJ, Sacks M, Mayer J Endothelial Progenitor Cells as a Sole Source for Ex vivo Seeding of Tissue-engineered Heart Valves. Tissue Eng. 2010;16(1):257-67 - PMID: 19698056 - PMCID: PMC2811057 - DOI: 10.1089/ten.TEA.2009.0424
Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer J, Aikawa E Intravital Molecular Imaging of Small-Diameter Tissue-Engineered Vascular Grafts: A Feasibility Study. Tissue Eng. 2010;16(4):597-607 - PMID: 19751103 - PMCID: PMC7875113 - DOI: 10.1089/ten.TEC.2009.0466
Whitley MJ, Weissleder R, Kirsch DG Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer. Semin Radiat Oncol. 2015;25(4):313-21 - PMID: 26384279 - PMCID: PMC4575408 - DOI: 10.1016/j.semradonc.2015.05.005
Schulz RB, Ripoll J, Ntziachristos V Experimental fluorescence tomography of tissues with noncontact measurements. IEEE T Med Imaging. 2004;23(4):492-500 - PMID: 15084074 - DOI: 10.1109/TMI.2004.825633
Zacharakis G, Ripoll J, Weissleder R, Ntziachristos V. Fluorescent protein tomography scanner for small animal imaging IEEE T Med Imaging. 2005;24(7):878-85 - PMID: 16011317 - DOI: 10.1109/tmi.2004.843254
Marias K, Ripoll J, Meyer H, Ntziachristos V, Orphanoudakis S. Image analysis for assessing molecular activity changes in time-dependent geometries IEEE T Med Imaging. 2005;24(7):894-900 - PMID: 16011319 - DOI: 10.1109/tmi.2005.848612
Soubret A, Ripoll J, Ntziachristos V. Accuracy of fluorescent tomography in the presence of heterogeneities: study of the normalized Born ratio IEEE T Med Imaging. 2005;24(10):1377-86 - PMID: 16229423 - DOI: 10.1109/tmi.2005.857213
Hyde D, Miller E, Brooks DH, Ntziachristos V A statistical approach to inverting the Born ratio. IEEE T Med Imaging. 2007;26 (7):893-905 - PMID: 17649903 - DOI: 10.1109/TMI.2007.895467
Lasser T, Soubret A, Ripoll J, Ntziachristos V Surface Reconstruction for free-space 360 degrees fluorescence molecular tomography and the effects of animal motion. IEEE T Med Imaging. 2008;27(2):188-94 - PMID: 18334440 - DOI: 10.1109/TMI.2007.904662
Belleannee C, Da Silva N, Shum WW, Marsolais M, Laprade R, Brown D, Breton S Segmental Expression of the Bradykinin Type 2 Receptor in Rat Efferent Ducts and Epididymis and Its Role in the Regulation of Aquaporin 9. Biol Reprod. 2009;80(1):134-43 - PMID: 18829705 - PMCID: PMC2804812 - DOI: 10.1095/biolreprod.108.070797
Pittet MJ Behavior of immune players in the tumor microenvironment. Curr Opin Oncol. 2009;21(1):53-9 - PMID: 19125019 - PMCID: PMC2901856 - DOI: 10.1097/CCO.0b013e32831bc38a
Jensen LJ, Schmitt BM, Berger UV, Nsumu NN, Boron WF, Hediger MA, Brown D, Breton S Localization of sodium bicarbonate cotransporter (NBC) protein and messenger ribonucleic acid in rat epididymis. Biol Reprod. 1999;60(3):573-9 - PMID: 10026101 - DOI: 10.1095/biolreprod60.3.573
Jensen LJ, Stuart-Tilley AK, Peters LL, Lux SE, Alper SL, Breton S Immunolocalization of AE2 anion exchanger in rat and mouse epididymis. Biol Reprod. 1999;61(4):973-80 - PMID: 10491632 - DOI: 10.1095/biolreprod61.4.973
Herak-Kramberger CM, Sabolić I, Blanusa M, Smith PJ, Brown D, Breton S Cadmium inhibits vacuolar H(+)ATPase-mediated acidification in the rat epididymis. Biol Reprod. 2000;63(2):599-606 - PMID: 10906070 - DOI: 10.1095/biolreprod63.2.599
Herak-Kramberger CM, Breton S, Brown D, Kraus O, Sabolic I Distribution of the vacuolar H+ atpase along the rat and human male reproductive tract. Biol Reprod. 2001;64(6):1699-707 - PMID: 11369598 - DOI: 10.1095/biolreprod64.6.1699
Pastor-Soler N, Bagnis C, Sabolic I, Tyszkowski R, McKee M, Van Hoek A, Breton S, Brown D Aquaporin 9 expression along the male reproductive tract. Biol Reprod. 2001;65(2):384-93 - PMID: 11466204 - DOI: 10.1095/biolreprod65.2.384
Fisher JS, Pastor-Soler N, Sharpe RM, Breton S Modulation of the onset of postnatal development of H(+)-ATPase-rich cells by steroid hormones in rat epididymis. Biol Reprod. 2002;67(4):1106-14 - PMID: 12297525 - DOI: 10.1095/biolreprod67.4.1106
Pastor-Soler N, Isnard-Bagnis C, Herak-Kramberger C, Sabolic I, Van Hoek A, Brown D, Breton S Expression of aquaporin 9 in the adult rat epididymal epithelium is modulated by androgens. Biol Reprod. 2002;66(6):1716-22 - PMID: 12021052 - DOI: 10.1095/biolreprod66.6.1716
Da Silva N, Silberstein C, Beaulieu V, Pietrement C, Van Hoek AN, Brown D, Breton S Postnatal expression of aquaporins in epithelial cells of the rat epididymis. Biol Reprod. 2005;74(2):427-38 - PMID: 16221990 - DOI: 10.1095/biolreprod.105.044735
Pietrement C, Sun-Wada GH, Silva ND, McKee M, Marshansky V, Brown D, Futai M, Breton S Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis. Biol Reprod. 2005;74(1):185-94 - PMID: 16192400 - DOI: 10.1095/biolreprod.105.043752
Shum WW, Smith TB, Cortez-Retamozo V, Grigoryeva LS, Roy JW, Hill E, Pittet MJ, Breton S, Da Silva N Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis. Biol Reprod. 2014;90(5):90 - PMID: 24648397 - PMCID: PMC4076373 - DOI: 10.1095/biolreprod.113.116681
Kim B, Roy J, Shum WW, Da Silva N, Breton S Role of Testicular Luminal Factors on Basal Cell Elongation and Proliferation in the Mouse Epididymis. Biol Reprod. 2014;92(1):9 - PMID: 25411392 - PMCID: PMC4434934 - DOI: 10.1095/biolreprod.114.123943
Kim B, Breton S The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis. Biol Reprod. 2015;94(1):22 - PMID: 26658708 - PMCID: PMC4809559 - DOI: 10.1095/biolreprod.115.134965
Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R In vivo tracking of neural progenitor cell migration to glioblastomas Hum Gene Ther. 2003;14:1247-54 - PMID: 12952596 - DOI: 10.1089/104303403767740786
Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005;16:1367-76 - PMID: 16390268 - DOI: 10.1089/hum.2005.16.1367
Messerli SM, Prabhakar S, Tang Y, Mahmood U, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006;17(1):20-30 - PMID: 16409122 - DOI: 10.1089/hum.2006.17.20
Schellingerhout D, Bogdanov A, Marecos E, Spear M, Breakefield X, Weissleder R Mapping the in vivo distribution of herpes simplex virions. Hum Gene Ther. 1998;9(11):1543-9 - PMID: 9694153 - DOI: 10.1089/hum.1998.9.11-1543
Rainov NG, Zimmer C, Chase M, Kramm CM, Chiocca EA, Weissleder R, Breakefield XO Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Hum Gene Ther. 1995;6(12):1543-52 - PMID: 8664379 - DOI: 10.1089/hum.1995.6.12-1543
Ji H, Wang TL, Chen CH, Pai SI, Hung CF, Lin KY, Kurman RJ, Pardoll DM, Wu TC Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors. Hum Gene Ther. 1999;10(17):2727-40 - PMID: 10584920 - DOI: 10.1089/10430349950016474
Sabolic I, Herak-Kramberger CM, Antolovic R, Breton S, Brown D Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin. Toxicology. 2005;218(2-3):149-63 - PMID: 16288946 - DOI: 10.1016/j.tox.2005.10.009
Vinegoni C, Lee S, Aguirre AD, Weissleder R New techniques for motion-artifact-free in vivo cardiac microscopy. Front Physiol. 2015;6:147 - PMID: 26029116 - PMCID: PMC4428079 - DOI: 10.3389/fphys.2015.00147
Montet X, Yuan H, Weissleder R, Josephson L Enzyme-based visualization of receptor-ligand binding in tissues. Lab Invest. 2006;86(5):517-25 - PMID: 16568109 - DOI: 10.1038/labinvest.3700404
Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer. Lab Invest. 2006;86(6):599-609 - PMID: 16607378 - DOI: 10.1038/labinvest.3700421
Deguchi JO, Huang H, Libby P, Aikawa E, Whittaker P, Sylvan J, Lee RT, Aikawa M Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II. Lab Invest. 2009;89(3):315-26 - PMID: 19153555 - PMCID: PMC2932654 - DOI: 10.1038/labinvest.2008.167
Larson AM, Hedgire SS, Deshpande V, Stemmer-Rachamimov AO, Harisinghani MG, Ferrone CR, Shah U, Thiele EA Pancreatic neuroendocrine tumors in patients with tuberous sclerosis complex. Clin Genet. 2011;82(6):558-63 - PMID: 22035404 - DOI: 10.1111/j.1399-0004.2011.01805.x
Lienard D, Rimoldi D, Marchand M, Dietrich P, van Baren N, Geldhof C, Batard P, Guillaume P, Ayyoub M, Pittet M, Zippelius A, Fleischhauer K, Lejeune F, Cerottini J, Romero P, Speiser D Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA. Cancer Immunol Immunther. 2004;4:4 - PMID: 15149168
Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J Am Med Inform Assoc. 2015;22(5):993-1000 - PMID: 25929596 - PMCID: PMC4986664 - DOI: 10.1093/jamia/ocv034
Swirski FK, Nahrendorf M Imaging macrophage development and fate in atherosclerosis and myocardial infarction. Immunol Cell Biol. 2013;91(4):297-303 - PMID: 23207281 - PMCID: PMC3875224 - DOI: 10.1038/icb.2012.72
Kang HW, Weissleder R, Bogdanov A Jr Targeting of MPEG-protected polyamino acid carrier to human E-selectin in vitro Amino Acids. 2002;23:301-8 - PMID: 12373551 - DOI: 10.1007/s00726-001-0142-2
Yoshida S, Kurokohchi K, Ueno T, Yoshino M, Shimada M, Masaki T Hepatic von Meyenburg complex: a trigger of severe portal hypertension. Liver Int. 2008;29(4):614-5 - PMID: 19018981 - PMCID: PMC2711260 - DOI: 10.1111/j.1478-3231.2008.01903.x
Krapf D, Chun Ruan Y, Wertheimer EV, Battistone MA, Pawlak JB, Sanjay A, Pilder SH, Cuasnicu P, Breton S, Visconti PE cSrc is necessary for epididymal development and is incorporated into sperm during epididymal transit. Dev Biol. 2012;369(1):43-53 - PMID: 22750823 - PMCID: PMC3424100 - DOI: 10.1016/j.ydbio.2012.06.017
Shah K, Weissleder R Molecular Optical Imaging: Applications Leading to the Development of Present Day Therapeutics NeuroRx. 2005;2:215-225 - PMID: 15897946 - PMCID: PMC1064987 - DOI: 10.1602/neurorx.2.2.215
Brown D, Hasler U, Nunes P, Bouley R, Lu H Phosphorylation events and the modulation of aquaporin 2 cell surface expression. Curr Opin Nephrol Hypertens. 2008;17(5):491-8 - PMID: 18695390 - PMCID: PMC3774073 - DOI: 10.1097/MNH.0b013e3283094eb1
Comper WD, Russo LM The glomerular filter: an imperfect barrier is required for perfect renal function. Curr Opin Nephrol Hypertens. 2009;18(4):336-42 - PMID: 19474730 - DOI: 10.1097/MNH.0b013e32832cb96a
Marshansky V, Ausiello DA, Brown D Physiological importance of endosomal acidification: potential role in proximal tubulopathies. Curr Opin Nephrol Hypertens. 2002;11(5):527-37 - PMID: 12187318 - DOI: 10.1097/00041552-200209000-00009
Xu C, Mu L, Roes I, Miranda-Nieves D, Nahrendorf M, Ankrum JA, Zhao W, Karp JM Nanoparticle-based monitoring of cell therapy. Nanotechnology. 2011;22(49):494001 - PMID: 22101191 - PMCID: PMC3334527 - DOI: 10.1088/0957-4484/22/49/494001
Huang X, Li Y, Im H, Yarimaga O, Kim J, Jang D, Cho S, Cai W, Choi Y Morphology-controlled SWCNT/polymeric microsphere arrays by a wet chemical self-assembly technique and their application for sensors Nanotechnology. 2006;17(12):2988
Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2008;44:190-198 - PMID: 19007918 - PMCID: PMC2656637 - DOI: 10.1016/j.bone.2008.10.036
Vinegoni C, Ralston T, Tan W, Luo W, Marks DL, Boppart SA Integrated structural and functional imaging combining spectral-domain optical coherence and multiphoton microscopy Appl Phys Lett. 2006;88:051105
Marks DL, Vinegoni C, Bredfeldt JS, Boppart SA Interferometric differentiation between resonant Coherent Anti-Stokes Raman Scattering and nonresonant four-wave-mixing processes Appl Phys Lett. 2004;85:5787-89
Pellegrini V, Colombelli R, Vinegoni C, Rubini S, Lantier R, Franciosi A, Beltram F, Pavesi L Second harmonic generation in ZnSe microcavity. Appl. Phys. Lett. 1999;74:1945-47 Appl Phys Lett. 1999;74:1945-47
Cazzanelli M, Cole D, Donegan JF, Lunney JG, Middleton PG, O'Donnell KP, Vinegoni C, Pavesi L Photoluminescence of localized excitons in pulsed laser deposited GaN Appl Phys Lett. 1998;73:3390-2
Hooper B, Domankevitz Y, Anderson R, Lin CP Optical temperature probe Appl Phys Lett. 2001;78:2381-3
Lin CP, Kelly MW Cavitation and acoustic emission around laser-heated microparticles Appl Phys Lett. 1998;72:2800
Hunt TP, Lee H, and Westervelt RM Addressable micropost array for the dielectrophoretic manipulation of particles in fluid Appl Phys Lett. 0;85(26):6421-23
Lee H, Purdon AM, Westervelt RM Manipulation of biological cells using a microelectromagnet matrix Appl Phys Lett. 0;85(6):1063-65
Fass DM, Shah R, Ghosh B, Hennig K, Norton S, Zhao WN, Reis SA, Klein PS, Mazitschek R, Maglathlin RL, Lewis TA, Haggarty SJ Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. ACS Med Chem Lett. 2010;2(1):39-42 - PMID: 21874153 - PMCID: PMC3161516 - DOI: 10.1021/ml1001954
Lesuffleur A, Im H, Lindquist NC, Oh S Periodic nanohole arrays with shape-enhanced plasmon resonance as real-time biosensors Appl Phys Lett. 2007;90:243110
Taktak S, Weissleder R, Josephson L Electrode Chemistry Yields a Nanoparticle-Based NMR Sensor for Calcium. Langmuir. 2008;24 (14):7596-7598 - PMID: 18558729 - PMCID: PMC2748273 - DOI: 10.1021/la8006298
Huang XJ, Ryu SW, Im HS, Choi YK Wet chemical needlelike assemblies of single-walled carbon nanotubes on a silicon surface. Langmuir. 2007;23(3):991-4 - PMID: 17241002 - DOI: 10.1021/la063144l
Smith RN, Ueno T, Ito T, Tanaka K, Shea SP, Abdi R Chemokines and chronic heart allograft rejection. Transplantation. 2007;84(3):442-4 - PMID: 17700176 - DOI: 10.1097/01.tp.0000277535.02541.30
Ueno T, Yamada A, Ito T, Yeung MY, Gorbatov R, Shimizu T, Abdi R, Sayegh MH, Auchincloss H, Najafian N Role of Nuclear Factor of Activated T Cell (NFAT) Transcription Factors in Skin and Vascularized Cardiac Allograft Rejection. Transplantation. 2011;92(5):e26-e27 - PMID: 21866037 - DOI: 10.1097/TP.0b013e318228061c
Tremblay J, Chen H, Peng J, Kunes J, Vu MD, Der Sarkissian S, deBlois D, Bolton AE, Gaboury L, Marshansky V, Gouadon E, Hamet P Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy. Transplantation. 2002;74(10):1425-33 - PMID: 12451244 - DOI: 10.1097/00007890-200211270-00015
Ansari MJ, Fiorina P, Dada S, Guleria I, Ueno T, Yuan X, Trikudanathan S, Smith RN, Freeman G, Sayegh MH Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. Clin Immunol. 2007;126(2):140-7 - PMID: 17889619 - DOI: 10.1016/j.clim.2007.07.019
Pirri P, Vinegoni C, Pavesi L Optical and photoluminescence properties of a-Si(1-x)Nx:H films deposited by PECVD Phys Rev B. 2000;61:4693-8
Giorgis F, Pirri CF, Vinegoni C, Pavesi L Luminescence processes in amorphous silicon-nitride nanometric multilayers Phys Rev B. 1999;60:11572-76
Nahrendorf M, Weissleder R, Ertl G Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction? PLoS ONE. 2006;1:e48 - PMID: 17183677 - PMCID: PMC1762326 - DOI: 10.1371/journal.pone.0000048
Kelly KA, Carson J, McCarthy JR, Weissleder R Novel Peptide Sequence ("IQ-tag") with High Affinity for NIR Fluorochromes Allows Protein and Cell Specific Labeling for In Vivo Imaging. PLoS ONE. 2007;2:e665 - PMID: 17653285 - PMCID: PMC1919420 - DOI: 10.1371/journal.pone.0000665
Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. PLoS ONE. 2007;2(10):e1075 - PMID: 17957257 - PMCID: PMC2034600 - DOI: 10.1371/journal.pone.0001075
Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Plough HL, Barrett TA, Weissleder R, Khazaie K Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS ONE. 2008;3:e2916 - PMID: 18698347 - PMCID: PMC2488397 - DOI: 10.1371/journal.pone.0002916
Badr C, Hewett J, Breakefield X, Tannous B A Highly Sensitive Assay for Monitoring the Secretory Pathway and ER Stress PLoS ONE. 0;6:e571
Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. PLoS ONE. 2008;3(12):e3949 - PMID: 19079609 - PMCID: PMC2597248 - DOI: 10.1371/journal.pone.0003949
Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS ONE. 2009;4(2):e4471 - PMID: 19214237 - PMCID: PMC2637605 - DOI: 10.1371/journal.pone.0004471
Wildgruber M, Lee H, Chudnovskiy A, Yoon T, Etzrodt M, Pittet M, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski F Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors. PLoS ONE. 2009;4(5):e5663 - PMID: 19461894 - PMCID: PMC2680949 - DOI: 10.1371/journal.pone.0005663
Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S Systems-level modeling of cancer-fibroblast interaction. PLoS ONE. 2009;4(9):e6888 - PMID: 19727395 - PMCID: PMC2731225 - DOI: 10.1371/journal.pone.0006888
Thurber GM, Figueiredo JL, Weissleder R Multicolor Fluorescent Intravital Live Microscopy (FILM) for Surgical Tumor Resection in a Mouse Xenograft Model. PLoS ONE. 2009;4(11):e8053 - PMID: 19956597 - PMCID: PMC2779447 - DOI: 10.1371/journal.pone.0008053
Miranda KC, Karet FE, Brown D An Extended Nomenclature for Mammalian V-ATPase Subunit Genes and Splice Variants. PLoS ONE. 2010;5(3):e9531 - PMID: 20224822 - PMCID: PMC2835735 - DOI: 10.1371/journal.pone.0009531
Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models. PLoS ONE. 2010;5(4):e10032 - PMID: 20386609 - PMCID: PMC2850367 - DOI: 10.1371/journal.pone.0010032
Berny MA, Munnix IC, Auger JM, Schols SE, Cosemans JM, Panizzi P, Bock PE, Watson SP, McCarty OJ, Heemskerk JW Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear. PLoS ONE. 2010;5(4):e10415 - PMID: 20454680 - PMCID: PMC2861630 - DOI: 10.1371/journal.pone.0010415
Gibert Y, Lattanzi VJ, Zhen AW, Vedder L, Brunet F, Faasse SA, Babitt JL, Lin HY, Hammerschmidt M, Fraenkel PG BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin. PLoS ONE. 2011;6(1):e14553 - PMID: 21283739 - PMCID: PMC3024971 - DOI: 10.1371/journal.pone.0014553
Thurber GM, Weissleder R A Systems Approach for Tumor Pharmacokinetics PLoS ONE. 2011;6(9):e24696 - PMID: 21935441 - PMCID: PMC3173470 - DOI: 10.1371/journal.pone.0024696
Settles M, Etzrodt M, Kosanke K, Schiemann M, Zimmermann A, Meier R, Braren R, Huber A, Rummeny EJ, Weissleder R, Swirski FK, Wildgruber M Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles. PLoS ONE. 2011;6(10):e25197 - PMID: 21984904 - PMCID: PMC3184946 - DOI: 10.1371/journal.pone.0025197
Ryan RJ, Nitta M, Borger D, Zukerberg LR, Ferry JA, Harris NL, Iafrate AJ, Bernstein BE, Sohani AR, Le LP EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas. PLoS ONE. 2011;6(12):e28585 - PMID: 22194861 - PMCID: PMC3237460 - DOI: 10.1371/journal.pone.0028585
Rice WL, Zhang Y, Chen Y, Matsuzaki T, Brown D, Lu HA Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells. PLoS ONE. 2012;7(2):e32843 - PMID: 22403603 - PMCID: PMC3293519 - DOI: 10.1371/journal.pone.0032843
Atkinson W*, Forghani R*, Wojtkiewicz GR, Pulli B, Iwamoto Y, Ueno T, Waterman P, Truelove J, Oklu R, Chen JW Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice PLoS ONE. 2012;7(3):e33671 - PMID: 22457780 - PMCID: PMC3310075 - DOI: 10.1371/journal.pone.0033671
Vinegoni C, Feruglio PF, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography. PLoS ONE. 2012;7(4):e34427 - PMID: 22509302 - PMCID: PMC3324534 - DOI: 10.1371/journal.pone.0034427
Staropoli JF, Haliw L, Biswas S, Garrett L, Hölter SM, Becker L, Skosyrski S, Da Silva-Buttkus P, Calzada-Wack J, Neff F, Rathkolb B, Rozman J, Schrewe A, Adler T, Puk O, Sun M, Favor J, Racz I, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Wolf E, Wurst W, Zimmer A, Lopez E, Harati H, Hill E, Krause DS, Guide J, Dragileva E, Gale E, Wheeler VC, Boustany RM, Brown DE, Breton S, Ruether K, Gailus-Durner V, Fuchs H, de Angelis MH, Cotman SL Large-Scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System. PLoS ONE. 2012;7(6):e38310 - PMID: 22701626 - PMCID: PMC3368842 - DOI: 10.1371/journal.pone.0038310
Malka R, Shochat E, Rom-Kedar V Bistability and bacterial infections. PLoS ONE. 2010;5(5):e10010 - PMID: 20463954 - PMCID: PMC2864736 - DOI: 10.1371/journal.pone.0010010
Chong NW, Koekemoer AL, Ounzain S, Samani NJ, Shin JT, Shaw SY STARS Is Essential to Maintain Cardiac Development and Function In Vivo via a SRF Pathway. PLoS ONE. 2012;7(7):e40966 - PMID: 22815879 - PMCID: PMC3399798 - DOI: 10.1371/journal.pone.0040966
Wu Q, Sun CC, Lin HY, Babitt JL Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs). PLoS ONE. 2012;7(9):e46307 - PMID: 23029472 - PMCID: PMC3459908 - DOI: 10.1371/journal.pone.0046307
Păunescu TG, Rodriguez S, Benz E, McKee M, Tyszkowski R, Albers MW, Brown D Loss of the V-ATPase B1 Subunit Isoform Expressed in Non-Neuronal Cells of the Mouse Olfactory Epithelium Impairs Olfactory Function. PLoS ONE. 2012;7(9):e45395 - PMID: 23028982 - PMCID: PMC3447883 - DOI: 10.1371/journal.pone.0045395
Wu X, Yung LM, Cheng WH, Yu PB, Babitt JL, Lin HY, Xia Y Hepcidin Regulation by BMP Signaling in Macrophages Is Lipopolysaccharide Dependent. PLoS ONE. 2012;7(9):e44622 - PMID: 23028567 - PMCID: PMC3441567 - DOI: 10.1371/journal.pone.0044622
Rice WL, Van Hoek AN, Păunescu TG, Huynh C, Goetze B, Singh B, Scipioni L, Stern LA, Brown D High resolution helium ion scanning microscopy of the rat kidney. PLoS ONE. 2013;8(3):e57051 - PMID: 23505418 - PMCID: PMC3591388 - DOI: 10.1371/journal.pone.0057051
Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerté M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR Soluble Guanylate Cyclase α1-Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma. PLoS ONE. 2013;8(3):e60156 - PMID: 23527308 - PMCID: PMC3603933 - DOI: 10.1371/journal.pone.0060156
Giedt RJ, Koch PD, Weissleder R Single Cell Analysis of Drug Distribution by Intravital Imaging. PLoS ONE. 2013;8(4):e60988 - PMID: 23593370 - PMCID: PMC3622689 - DOI: 10.1371/journal.pone.0060988
Prabhakar S, Goto J, Zuang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO Stochastic model of tsc1 lesions in mouse brain. PLoS ONE. 2013;8(5):e64224 - PMID: 23696872 - PMCID: PMC3655945 - DOI: 10.1371/journal.pone.0064224
Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells. PLoS ONE. 2013;8(7):e67590 - PMID: 23844039 - PMCID: PMC3699654 - DOI: 10.1371/journal.pone.0067590
Pulli B, Ali M, Forghani R, Schob S, Hsieh KL, Wojtkiewicz G, Linnoila JJ, Chen JW Measuring myeloperoxidase activity in biological samples. PLoS ONE. 2013;8(7):e67976 - PMID: 23861842 - PMCID: PMC3702519 - DOI: 10.1371/journal.pone.0067976
Carlson AL, Fujisaki J, Wu J, Runnels JM, Turcotte R, Spencer JA, Celso CL, Scadden DT, Strom TB, Lin CP Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label. PLoS ONE. 2013;8(8):e69257 - PMID: 23990881 - PMCID: PMC3753322 - DOI: 10.1371/journal.pone.0069257
Mortensen LJ, Levy O, Phillips JP, Stratton T, Triana B, Ruiz JP, Gu F, Karp JM, Lin CP Quantification of Mesenchymal Stem Cell (MSC) Delivery to a Target Site Using In Vivo Confocal Microscopy. PLoS ONE. 2013;8(10):e78145 - PMID: 24205131 - PMCID: PMC3812161 - DOI: 10.1371/journal.pone.0078145
Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL Modeling disease severity in multiple sclerosis using electronic health records. PLoS ONE. 2013;8(11):e78927 - PMID: 24244385 - PMCID: PMC3823928 - DOI: 10.1371/journal.pone.0078927
Kim E, Yang K, Weissleder R Bioorthogonal Small Molecule Imaging Agents Allow Single-Cell Imaging of MET PLoS ONE. 2013;8 (11):e81275 - PMID: 24265843 - PMCID: PMC3827223 - DOI: 10.1371/journal.pone.0081275
Meynard D, Sun CC, Wu Q, Chen W, Chen S, Nelson CN, Waters MJ, Babitt JL, Lin HY Inflammation Regulates TMPRSS6 Expression via STAT5. PLoS ONE. 2013;8(12):e82127 - PMID: 24376517 - PMCID: PMC3871639 - DOI: 10.1371/journal.pone.0082127
Elman JS, Murray RM, Wang F, Shen K, Gao S, Conway KE, Yarmush ML, Tannous BA, Weissleder R, Parekkadan B Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells. PLoS ONE. 2014;9(2):e89882 - PMID: 24587097 - PMCID: PMC3931832 - DOI: 10.1371/journal.pone.0089882
Miranda KC, Bond DT, Levin JZ, Adiconis X, Sivachenko A, Russ C, Brown D, Nusbaum C, Russo LM Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. PLoS ONE. 2014;9(5):e96094 - PMID: 24816817 - PMCID: PMC4015934 - DOI: 10.1371/journal.pone.0096094
Mehan WA, González RG, Buchbinder BR, Chen JW, Copen WA, Gupta R, Hirsch JA, Hunter GJ, Hunter S, Johnson JM, Kelly HR, Larvie M, Lev MH, Pomerantz SR, Rapalino O, Rincon S, Romero JM, Schaefer PW, Shah V Optimal Brain MRI Protocol for New Neurological Complaint. PLoS ONE. 2014;9(10):e110803 - PMID: 25343371 - PMCID: PMC4208779 - DOI: 10.1371/journal.pone.0110803
Hsieh LC, Chen JW, Wang LY, Tsang YM, Shueng PW, Liao LJ, Lo WC, Lin YC, Tseng CF, Kuo YS, Jhuang JY, Tien HJ, Juan HF, Hsieh CH Predicting the severity and prognosis of trismus after intensity-modulated radiation therapy for oral cancer patients by magnetic resonance imaging. PLoS ONE. 2014;9(3):e92561 - PMID: 24658376 - PMCID: PMC3962418 - DOI: 10.1371/journal.pone.0092561
Kessinger CW, Kim JW, Henke PK, Thompson B, McCarthy JR, Hara T, Sillesen M, Margey RJ, Libby P, Weissleder R, Lin CP, Jaffer FA Statins Improve the Resolution of Established Murine Venous Thrombosis: Reductions in Thrombus Burden and Vein Wall Scarring. PLoS ONE. 2015;10(2):e0116621 - PMID: 25680183 - PMCID: PMC4334538 - DOI: 10.1371/journal.pone.0116621
Azroyan A, Cortez-Retamozo V, Bouley R, Liberman R, Ruan YC, Kiselev E, Jacobson KA, Pittet MJ, Brown D, Breton S Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor. PLoS ONE. 2015;10(3):e0121419 - PMID: 25799465 - PMCID: PMC4370445 - DOI: 10.1371/journal.pone.0121419
Rotem A, Ram O, Shoresh N, Sperling RA, Schnall-Levin M, Zhang H, Basu A, Bernstein BE, Weitz DA High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics. PLoS ONE. 2015;10(5):e0116328 - PMID: 26000628 - PMCID: PMC4441486 - DOI: 10.1371/journal.pone.0116328
Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M Engineered Trehalose Permeable to Mammalian Cells. PLoS ONE. 2015;10(6):e0130323 - PMID: 26115179 - PMCID: PMC4482662 - DOI: 10.1371/journal.pone.0130323
Chung HJ, Pellegrini KL, Chung J, Wanigasuriya K, Jayawardene I, Lee K, Lee H, Vaidya VS, Weissleder R Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury. PLoS ONE. 2015;10(7):e0133417 - PMID: 26186708 - PMCID: PMC4506142 - DOI: 10.1371/journal.pone.0133417
Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS ONE. 2015;10(8):e0136651 - PMID: 26301417 - PMCID: PMC4547801 - DOI: 10.1371/journal.pone.0136651
Rice WL, Li W, Mamuya F, McKee M, Păunescu TG, Lu HA Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture. PLoS ONE. 2015;10(7):e0131719 - PMID: 26147297 - PMCID: PMC4493001 - DOI: 10.1371/journal.pone.0131719
Miller MA, Feng XJ, Li G, Rabitz HA Identifying biological network structure, predicting network behavior, and classifying network state with High Dimensional Model Representation (HDMR). PLoS ONE. 2012;7(6):e37664 - PMID: 22723838 - PMCID: PMC3377689 - DOI: 10.1371/journal.pone.0037664
Peng S, Wang JW, Karanam B, Wang C, Huh WK, Alvarez RD, Pai SI, Hung CF, Wu TC, Roden RB Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer. PLoS ONE. 2015;10(1):e116389 - PMID: 25560237 - PMCID: PMC4283968 - DOI: 10.1371/journal.pone.0116389
Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R Novel Factor XIII Probes for Blood Coagulation Imaging Chembiochem. 2003;4:897-899 - PMID: 12964167 - DOI: 10.1002/cbic.200300602
Tung CH, Gerszten RE, Jaffer FA, Weissleder R A novel near-infrared fluorescence sensor for detection of thrombin activation in blood Chembiochem. 2002;3:207-11 - PMID: 11921399 - DOI: 10.1002/1439-7633(20020301)3:2/3<207::AID-CBIC207>3.0.CO;2-B
Tung CH, Lin Y, Moon WK, Weissleder R A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging Chembiochem. 2002;3:784-6 - PMID: 12203978 - DOI: 10.1002/1439-7633(20020802)3:8<784::AID-CBIC784>3.0.CO;2-X
Perez JM, Josephson L, Weissleder R Use of magnetic nanoparticles as nanosensors to probe for molecular interactions Chembiochem. 2004;5:261-4 - PMID: 14997516 - DOI: 10.1002/cbic.200300730
Schellenberger EA, Reynolds F, Weissleder R, Josephson L Surface-functionalized nanoparticle library yields probes for apoptotic cells Chembiochem. 2004;5:275-9 - PMID: 14997519 - DOI: 10.1002/cbic.200300713
Schellenberger EA, Weissleder R, Josephson L Optimal modification of annexin v with fluorescent dyes Chembiochem. 2004;5:271-4 - PMID: 14997518 - DOI: 10.1002/cbic.200300741
Pham W, Kircher MF, Weissleder R, Tung CH Enhancing membrane permeability by Fatty acylation of oligoarginine peptides. Chembiochem. 2004;5(8):1148-51 - PMID: 15300843 - DOI: 10.1002/cbic.200400063
Koch AM, Reynolds F, Merkle HP, Weissleder R, Josephson L. Transport Of Surface-Modified Nanoparticles Through Cell Monolayers Chembiochem. 2005;6(2):337-345 - PMID: 15651046 - DOI: 10.1002/cbic.200400174
Law B, Weissleder R, Tung CH. Mechanism-Based Fluorescent Reporter for Protein Kinase A Detection Chembiochem. 2005;6(8):1361-1367 - PMID: 16010698 - DOI: 10.1002/cbic.200500027
Ho NH, Weissleder R, Tung CH A Self-Immolative Reporter For beta-Galactosidase Sensing. Chembiochem. 2007;8:560-566 - PMID: 17300128 - DOI: 10.1002/cbic.200600386
Reiner T, Earley S, Turetsky A, Weissleder R Bioorthogonal Small-Molecule Ligands for PARP1 Imaging in Living Cells. Chembiochem. 2010;11(17):2374-2377 - PMID: 20967817 - PMCID: PMC3034378 - DOI: 10.1002/cbic.201000477
Addicks E, Mazitschek R, Giannis A Synthesis and biological investigation of novel tricyclic benzodiazepinedione-based RGD analogues. Chembiochem. 2002;3(11):1078-88 - PMID: 12404633 - DOI: 10.1002/1439-7633(20021104)3:11<1078::AID-CBIC1078>3.0.CO;2-2
Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J Chemical Interrogation of the Malaria Kinome. Chembiochem. 2014;15(13):1920-30 - PMID: 25111632 - PMCID: PMC4237307 - DOI: 10.1002/cbic.201400025
Stone JH, Khosroshahi A, Deshpande V, Stone JR IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases. Arthritis Care Res. 2010;62(3):316-22 - PMID: 20391477 - DOI: 10.1002/acr.20095
Unizony S, Arias-Urdaneta L, Miloslavsky E, Arvikar S, Khosroshahi A, Keroack B, Stone J, Stone J Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, takayasu arteritis) and polymyalgia rheumatica. Arthritis Care Res (Hoboken). 2012;64(11):1720-9 - PMID: 22674883 - DOI: 10.1002/acr.21750
Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW Lipid and lipoprotein levels and trends in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013;65(12):2046-50 - PMID: 23925980 - PMCID: PMC4060244 - DOI: 10.1002/acr.22091
Da Silva N, Shum WW, El-Annan J, Paunescu TG, McKee M, Smith PJ, Brown D, Breton S Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit. Am J Physiol Cell Physiol. 2007;293(1):C199-210 - PMID: 17392376 - DOI: 10.1152/ajpcell.00596.2006
Pastor-Soler NM, Hallows KR, Smolak C, Gong F, Brown D, Breton S Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells. Am J Physiol Cell Physiol. 2008;294:C488-94 - PMID: 18160485 - PMCID: PMC4303256 - DOI: 10.1152/ajpcell.00537.2007
Roelen B, Cohen O, Raychowdhury M, Chadee D, Zhang Y, Kyriakis J, Alessandrini A, Lin H Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation. Am J Physiol Cell Physiol. 2003;285(4):C823-30 - PMID: 12801888 - DOI: 10.1152/ajpcell.00053.2003
Paunescu TG, Jones AC, Tyszkowski R, Brown D V-ATPase expression in the mouse olfactory epithelium. Am J Physiol Cell Physiol. 2008;295(4):C923-30 - PMID: 18667600 - PMCID: PMC2575830 - DOI: 10.1152/ajpcell.00237.2008
Nunes P, Hasler U, McKee M, Lu HA, Bouley R, Brown D A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2 (AQP2). Am J Physiol Cell Physiol. 2008;295(6):C1476-87 - PMID: 18799651 - PMCID: PMC2603565 - DOI: 10.1152/ajpcell.00344.2008
Belleannee C, Da Silva N, Shum WW, Brown D, Breton S Role of purinergic signaling pathways in V-ATPase recruitment to the apical membrane of acidifying epididymal clear cells. Am J Physiol Cell Physiol. 2010;298(4):C817-30 - PMID: 20071692 - PMCID: PMC2853219 - DOI: 10.1152/ajpcell.00460.2009
Da Silva N, Pisitkun T, Belleannee C, Miller LR, Nelson RD, Knepper MA, Brown D, Breton S Proteomic analysis of V-ATPase-rich cells harvested from the kidney and epididymis by fluorescence activated cell sorting. Am J Physiol Cell Physiol. 2010;298(6):C1326-42 - PMID: 20181927 - PMCID: PMC2889637 - DOI: 10.1152/ajpcell.00552.2009
Miller RL, Zhang P, Smith M, Beaulieu V, Paunescu TG, Brown D, Breton S, Nelson RD V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice. Am J Physiol Cell Physiol. 2005;288(5):C1134-44 - PMID: 15634743 - DOI: 10.1152/ajpcell.00084.2004
Paunescu TG, Da Silva N, Marshansky V, McKee M, Breton S, Brown D Expression of the 56-kDa B2 subunit isoform of the vacuolar H(+)-ATPase in proton-secreting cells of the kidney and epididymis. Am J Physiol Cell Physiol. 2004;287(1):C149-62 - PMID: 15013950 - DOI: 10.1152/ajpcell.00464.2003
Paunescu TG, Blazer-Yost BL, Vlahos CJ, Helman SI LY-294002-inhibitable PI 3-kinase and regulation of baseline rates of Na(+) transport in A6 epithelia. Am J Physiol Cell Physiol. 2000;279(1):C236-47 - PMID: 10898735 - DOI: 10.1152/ajpcell.2000.279.1.C236
Merkulova M, Hurtado-Lorenzo A, Hosokawa H, Zhuang Z, Brown D, Ausiello DA, Marshansky V Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution. Am J Physiol Cell Physiol. 2011;300(6):C1442-55 - PMID: 21307348 - PMCID: PMC3118619 - DOI: 10.1152/ajpcell.00076.2010
Shum WW, Da Silva N, Belleannee C, McKee M, Brown D, Breton S Regulation of V-ATPase recycling via a RhoA and ROCKII dependent pathway in epididymal clear cells. Am J Physiol Cell Physiol. 2011;301(1):C31-43 - PMID: 21411727 - PMCID: PMC3129830 - DOI: 10.1152/ajpcell.00198.2010
Stevens AL, Breton S, Gustafson CE, Bouley R, Nelson RD, Kohan DE, Brown D Aquaporin 2 is a vasopressin-independent, constitutive apical membrane protein in rat vas deferens. Am J Physiol Cell Physiol. 2000;278(4):C791-802 - PMID: 10751327 - DOI: 10.1152/ajpcell.2000.278.4.C791
Isnard-Bagnis C, Da Silva N, Beaulieu V, Yu AS, Brown D, Breton S Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM. Am J Physiol Cell Physiol. 2003;284(1):C220-32 - PMID: 12475763 - DOI: 10.1152/ajpcell.00374.2001
El-Annan J, Brown D, Breton S, Bourgoin S, Ausiello DA, Marshansky V Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ. Am J Physiol Cell Physiol. 2003;286(4):C768-78 - PMID: 14684384 - DOI: 10.1152/ajpcell.00250.2003
Winter C, Kampik NB, Vedovelli L, Rothenberger F, Paunescu TG, Stehberger PA, Brown D, John H, Wagner CA Aldosterone stimulates vacuolar H+-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C dependent pathway. Am J Physiol Cell Physiol. 2011;301(5):C1251-61 - PMID: 21832245 - PMCID: PMC3213922 - DOI: 10.1152/ajpcell.00076.2011
Bouley R, Lin HY, Raychowdhury MK, Marshansky V, Brown D, Ausiello DA Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway. Am J Physiol Cell Physiol. 2005;288(6):C1390-401 - PMID: 15677378 - DOI: 10.1152/ajpcell.00353.2004
Pitsillides CM, Runnels JM, Spencer JA, Zhi L, Wu MX, Lin CP Cell labeling approaches for fluorescence-based in vivo flow cytometry. Cytometry A. 2011;79(10):758-65 - PMID: 21905206 - PMCID: PMC3686107 - DOI: 10.1002/cyto.a.21125
Lisi S, Botta R, Pinchera A, Collins AB, Refetoff S, Arvan P, Bu G, Grasso L, Marshansky V, Bechoua S, Hurtado-Lorenzo A, Marcocci C, Brown D, McCluskey RT, Marinò M Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice. Am J Physiol Cell Physiol. 2005;290(4):C1160-7 - PMID: 16306127 - DOI: 10.1152/ajpcell.00382.2005
Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP An optical platform for cell tracking in adult zebrafish. Cytometry A. 2011;81(2):176-82 - PMID: 22162445 - PMCID: PMC6383206 - DOI: 10.1002/cyto.a.21167
Brown D, Bouley R, Paunescu TG, Breton S, Lu HA New insights into the dynamic regulation of water and acid/base balance by renal epithelial cells. Am J Physiol Cell Physiol. 2012;302(10):C1421-33 - PMID: 22460710 - PMCID: PMC3362000 - DOI: 10.1152/ajpcell.00085.2012
Yui N, Lu HA, Chen Y, Nomura N, Bouley R, Brown D Basolateral targeting and microtubule dependent transcytosis of the aquaporin-2 water channel. Am J Physiol Cell Physiol. 2012;304(1):C38-48 - PMID: 23015545 - PMCID: PMC3543574 - DOI: 10.1152/ajpcell.00109.2012
Roy JW, Hill E, Ruan YC, Vedovelli L, Paunescu T, Brown D, Breton S Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis. Am J Physiol Cell Physiol. 2013;305(4):C436-46 - PMID: 23761626 - PMCID: PMC3891217 - DOI: 10.1152/ajpcell.00410.2012
Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume. Cytometry A. 2014;85(4):332-8 - PMID: 24677669 - PMCID: PMC4717472 - DOI: 10.1002/cyto.a.22450
Nomura N, Nunes P, Bouley R, Nair AV, Shaw S, Ueda E, Pathomthongtaweechai N, Lu HA, Brown D High throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration. Am J Physiol Cell Physiol. 2014;307(7):C597-605 - PMID: 24944200 - PMCID: PMC4187055 - DOI: 10.1152/ajpcell.00154.2014
Zuk A, Bonventre JV, Brown D, Matlin KS Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney. Am J Physiol Cell Physiol. 1998;275(3):C711-C731 - PMID: 29585718 - DOI: 10.1152/ajpcell.1998.275.3.C711
Breton S, Hammar K, Smith PJS, Brown D Proton secretion in the male reproductive tract: involvement of Cl--independent HCO 3 - transport. Am J Physiol Cell Physiol. 1998;275(4):C1134-C1142 - PMID: 29585324 - DOI: 10.1152/ajpcell.1998.275.4.C1134
Shon SM, Park JH, Nahrendorf M, Schellingerhout D, Kim JY, Kang BT, Jeong SW, Kim EJ, Ryu JH, Kim K, Kwon IC, Lee DK, Lee MM, Kim DE Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque. Atherosclerosis. 2011;216(1):67-73 - PMID: 21334624 - DOI: 10.1016/j.atherosclerosis.2011.01.036
Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM Circulating angiogenic cell populations, vascular function, and arterial stiffness. Atherosclerosis. 2011;220(1):145-50 - PMID: 22093724 - PMCID: PMC3277804 - DOI: 10.1016/j.atherosclerosis.2011.10.015
Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors. Atherosclerosis. 2013;229(1):228-233 - PMID: 23701996 - PMCID: PMC3984590 - DOI: 10.1016/j.atherosclerosis.2013.04.017
Hink M, Shah K, Russinova E, de Vries S, Visser A Fluorescence Fluctuation Analysis of AtSERK and BRI1 Oligomerization. Biophys J. 2007;94(3):1052-62 - PMID: 17905839 - PMCID: PMC2186235 - DOI: 10.1529/biophysj.107.112003
Pitsillides C, Joe E, Wei X, Anderson R, Lin C Selective cell targeting with light-absorbing microparticles and nanoparticles. Biophys J. 2003;84:4023-32 - PMID: 12770906 - PMCID: PMC1302982 - DOI: 10.1016/S0006-3495(03)75128-5
Paunescu TG, Helman SI PGE(2) activation of apical membrane Cl(-) channels in A6 epithelia: impedance analysis. Biophys J. 2001;81(2):852-66 - PMID: 11463630 - PMCID: PMC1301558 - DOI: 10.1016/S0006-3495(01)75746-3
Paunescu TG, Helman SI cAmp activation of apical membrane Cl(-) channels: theoretical considerations for impedance analysis. Biophys J. 2001;81(2):838-51 - PMID: 11463629 - PMCID: PMC1301557 - DOI: 10.1016/S0006-3495(01)75745-1
Chow MJ, Turcotte R, Lin CP, Zhang Y Arterial Extracellular Matrix: A Mechanobiological Study of the Contributions and Interactions of Elastin and Collagen. Biophys J. 2014;106(12):2684-2692 - PMID: 24940786 - PMCID: PMC4070071 - DOI: 10.1016/j.bpj.2014.05.014
Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT, Weissleder R A Novel Method of Imaging Calcium Urolithiasis Using Fluorescence. J Urolology. 2008;179:1610-1614 - PMID: 18295253 - DOI: 10.1016/j.juro.2007.11.100
Da Silva N, Barton CR Macrophages and dendritic cells in the post-testicular environment. Cell Tissue Res. 2015;363(1):97-104 - PMID: 26337514 - PMCID: PMC4703462 - DOI: 10.1007/s00441-015-2270-0
Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, Snyder EY Neural stem cell biology may be well suited for improving brain tumor therapies Cancer J. 2003;9:189-204 - PMID: 12952304 - DOI: 10.1097/00130404-200305000-00007
Funovics M, Weissleder R, Tung CH Protease sensors for bioimaging Anal Bioanal Chem. 2003;377:956-63 - PMID: 12955390 - DOI: 10.1007/s00216-003-2199-0
Reynolds F, O'loughlin T, Weissleder R, Josephson L. Method of Determining Nanoparticle Core Weight Anal Bioanal Chem. 2005;77(3):814-817 - PMID: 15679348 - DOI: 10.1021/ac049307x
Feldman AS, McDougal WS, Harisinghani MG The potential of nanoparticle-enhanced imaging. Urol Oncol. 2008;26(1):65-73 - PMID: 18190834 - DOI: 10.1016/j.urolonc.2007.03.016
Huebert D, Kamal M, O'Donovan A, Bernstein B Genome-wide analysis of histone modifications by ChIP-on-chip. Methods. 2006;40(4):365-9 - PMID: 17101450 - DOI: 10.1016/j.ymeth.2006.07.032
Nahrendorf M, Badea C, Hedlund LW, Figueiredo JL, Sosnovik DE, Johnson GA, Weissleder R High Resolution Imaging of Murine Myocardial Infarction With Delayed Enhancement Cine Micro-CT. Am J Physiol-Heart C. 2007;292(6):3172-8 - PMID: 17322414 - PMCID: PMC2680216 - DOI: 10.1152/ajpheart.01307.2006
Nahrendorf M, Streif J, Hiller K, Hu K, Nordbeck P, Ritter O, Sosnovik D, Bauer L, Neubauer S, Jakob P, Ertl G, Spindler M, Bauer W Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics. Am J Physiol-Heart C. 2006;290(6):H2516-21 - PMID: 16415075 - DOI: 10.1152/ajpheart.01038.2005
Nahrendorf M, Hiller K, Greiser A, Kohler S, Neuberger T, Hu K, Waller C, Albrecht M, Neubauer S, Haase A, Ertl G, Bauer W Chronic coronary artery stenosis induces impaired function of remote myocardium: MRI and spectroscopy study in rat. Am J Physiol-Heart C. 2003;285(6):H2712-21 - PMID: 12933339 - DOI: 10.1152/ajpheart.00233.2003
Nahrendorf M, Hu K, Fraccarollo D, Hiller K, Haase A, Bauer W, Ertl G Time course of right ventricular remodeling in rats with experimental myocardial infarction. Am J Physiol-Heart C. 2003;284(1):H241-8 - PMID: 12388245 - DOI: 10.1152/ajpheart.00537.2002
Bian Y, Sun M, Silver M, Ho KK, Marchionni MA, Caggiano AO, Stone JR, Amende I, Hampton TG, Morgan JP, Yan X Neuregulin-1 Attenuated Doxorubicin-Induced Decrease in Cardiac Troponins. Am J Physiol-Heart C. 2009;297(6):H1974-83 - PMID: 19801490 - PMCID: PMC2793128 - DOI: 10.1152/ajpheart.01010.2008
Bouley R, Pastor-Soler N, Cohen O, McLaughlin M, Breton S, Brown D Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra). Am J Physiol Renal Physiol. 2005;288(6):F1103-12 - PMID: 15644488 - DOI: 10.1152/ajprenal.00337.2004
Yi X, Bouley R, Lin HY, Bechoua S, Sun TX, Del Re E, Shioda T, Raychowdhury MK, Lu HA, Abou-Samra AB, Brown D, Ausiello DA Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R. Am J Physiol Renal Physiol. 2007;292(5):F1303-13 - PMID: 17287200 - DOI: 10.1152/ajprenal.00441.2005
Paunescu TG, Da Silva N, Russo LM, McKee M, Lu HA, Breton S, Brown D Association Of Soluble Adenylyl Cyclase (sAC) With The V-ATPase In Renal Epithelial Cells. Am J Physiol Renal Physiol. 2007;294(1):F130-8 - PMID: 17959750 - DOI: 10.1152/ajprenal.00406.2007
Paunescu TG, Russo LM, Da Silva N, Kovacikova J, Mohebbi N, Van Hoek AN, McKee M, Wagner CA, Breton S, Brown D Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice. Am J Physiol Renal Physiol. 2007;293(6):F1915-26 - PMID: 17898041 - DOI: 10.1152/ajprenal.00160.2007
Lu HA, Matsuzaki T, Bouley R, Hasler U, Qin Q, Brown D The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells. Am J Physiol Renal Physiol. 2008;295(1):F290-4 - PMID: 18434387 - PMCID: PMC2494506 - DOI: 10.1152/ajprenal.00072.2008
Van Hoek AN, Bouley R, Lu YX, Silberstein CM, Brown D, Wax MB, Patil RV Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays. Am J Physiol Renal Physiol. 2009;296(6):F1396-404 - PMID: 19297454 - PMCID: PMC2692439 - DOI: 10.1152/ajprenal.00018.2009
Bouley R, Palomino Z, Tang SS, Nunes P, Kobori H, Lu HA, Shum WW, Sabolic I, Brown D, Ingelfinger JR, Jung FF Angiotensin II and Hypertonicity Modulate Proximal Tubular Aquaporin 1 (AQP1) Expression. Am J Physiol Renal Physiol. 2009;297(6):F1575-86 - PMID: 19776169 - PMCID: PMC2801332 - DOI: 10.1152/ajprenal.90762.2008
Paunescu TG, Ljubojevic M, Russo LM, Winter C, McLaughlin MM, Wagner CA, Breton S, Brown D Cyclic AMP stimulates apical V-ATPase accumulation, microvillar elongation and proton extrusion in kidney collecting duct A-intercalated cells. Am J Physiol Renal Physiol. 2010;298(3):F643-54 - PMID: 20053793 - PMCID: PMC2838605 - DOI: 10.1152/ajprenal.00584.2009
Zhuang Z, Marshansky V, Breton S, Brown D Is caveolin involved in normal proximal tubule (PT) function? Presence in model PT systems but absence in situ. Am J Physiol Renal Physiol. 2010;300(1):F199-206 - PMID: 20980408 - PMCID: PMC3023221 - DOI: 10.1152/ajprenal.00513.2010
Li W, Zhang Y, Bouley R, Chen Y, Matsuzaki T, Nunes P, Hasler U, Brown D, Lu HA Simvastatin Enhances Aquaporin 2 Surface Expression and Urinary Concentration in Vasopressin Deficient Brattleboro Rats through Modulation of Rho GTPase. Am J Physiol Renal Physiol. 2011;301(2):F309-18 - PMID: 21511701 - PMCID: PMC3154588 - DOI: 10.1152/ajprenal.00001.2011
Breton S, Nsumu NN, Galli T, Sabolic I, Smith PJ, Brown D Tetanus toxin-mediated cleavage of cellubrevin inhibits proton secretion in the male reproductive tract. Am J Physiol Renal Physiol. 2000;278(5):F717-25 - PMID: 10807583 - DOI: 10.1152/ajprenal.2000.278.5.F717
Silver RB, Breton S, Brown D Potassium depletion increases proton pump (H(+)-ATPase) activity in intercalated cells of cortical collecting duct. Am J Physiol Renal Physiol. 2000;279(1):F195-202 - PMID: 10894802 - DOI: 10.1152/ajprenal.2000.279.1.F195
Bagnis C, Marshansky V, Breton S, Brown D Remodeling the cellular profile of collecting ducts by chronic carbonic anhydrase inhibition. Am J Physiol Renal Physiol. 2001;280(3):F437-48 - PMID: 11181405 - DOI: 10.1152/ajprenal.2001.280.3.F437
Bagnis C, Marsolais M, Biemesderfer D, Laprade R, Breton S Na+/H+-exchange activity and immunolocalization of NHE3 in rat epididymis. Am J Physiol Renal Physiol. 2001;280(3):F426-36 - PMID: 11181404 - DOI: 10.1152/ajprenal.2001.280.3.F426
Breton S, Inoue T, Knepper MA, Brown D Antigen retrieval reveals widespread basolateral expression of syntaxin 3 in renal epithelia. Am J Physiol Renal Physiol. 2002;282(3):F523-9 - PMID: 11832435 - DOI: 10.1152/ajprenal.00128.2001
Zharkikh L, Zhu X, Stricklett PK, Kohan DE, Chipman G, Breton S, Brown D, Nelson RD Renal principal cell-specific expression of green fluorescent protein in transgenic mice. Am J Physiol Renal Physiol. 2002;283(6):F1351-64 - PMID: 12426236 - DOI: 10.1152/ajprenal.0224.2001
Breton S, Brown D New insights into the regulation of V-ATPase-dependent proton secretion. Am J Physiol Renal Physiol. 2006;292(1):F1-10 - PMID: 17032935 - DOI: 10.1152/ajprenal.00340.2006
Bouley R, Nunes P, Andriopoulos B, McLaughlin MM, Webber MJ, Lin HY, Babitt JL, Gardella TJ, Ausiello DA, Brown D Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin. Am J Physiol Renal Physiol. 2012;304(5):F553-64 - PMID: 23235478 - PMCID: PMC3602717 - DOI: 10.1152/ajprenal.00438.2011
Vedovelli L, Rothermel JT, Finberg KE, Wagner CA, Azroyan A, Hill E, Breton S, Brown D, Paunescu TG Altered V-ATPase expression in renal intercalated cells isolated from B1-subunit deficient mice by fluorescence activated cell sorting. Am J Physiol Renal Physiol. 2012;304(5):F522-32 - PMID: 23269648 - PMCID: PMC3602708 - DOI: 10.1152/ajprenal.00394.2012
Paunescu TG, Lu HA, Russo LM, Pastor-Soler NM, McKee M, McLaughlin MM, Bartlett BE, Breton S, Brown D Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells. Am J Physiol Renal Physiol. 2013;305(12):F1783-F1795 - PMID: 24133120 - PMCID: PMC3882446 - DOI: 10.1152/ajprenal.00622.2012
Lu H, Sun TX, Bouley R, Blackburn K, McLaughlin M, Brown D Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2. Am J Physiol Renal Physiol. 2003;286(2):F233-43 - PMID: 14519593 - DOI: 10.1152/ajprenal.00179.2003
Herak-Kramberger CM, Breljak D, Ljubojević M, Matokanovic M, Lovric M, Rogic D, Brzica H, Vrhovac I, Karaica D, Micek V, Ivkovic Dupor J, Brown D, Sabolic I Sex-dependent expression of water channel AQP1 along the rat nephron. Am J Physiol Renal Physiol. 2015;308(8):F809-21 - PMID: 25656365 - PMCID: PMC4398837 - DOI: 10.1152/ajprenal.00368.2014
Arthur J, Huang J, Nomura N, Jin WW, Li W, Cheng X, Brown D, Lu HJ Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells. Am J Physiol Renal Physiol. 2015;309(8):F673-9 - PMID: 26290367 - PMCID: PMC4609919 - DOI: 10.1152/ajprenal.00152.2015
Alper SL, Stuart-Tilley AK, Biemesderfer D, Shmukler BE, Brown D Immunolocalization of AE2 anion exchanger in rat kidney. Am J Physiol Renal Physiol. 1997;273(4):F601-F614 - PMID: 29587100 - DOI: 10.1152/ajprenal.1997.273.4.F601
Shayakul C, Kanai Y, Lee WS, Brown D, Rothstein JD, Hediger MA Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. Am J Physiol Renal Physiol. 1997;273(6):F1023-F1029 - PMID: 29586122 - DOI: 10.1152/ajprenal.1997.273.6.F1023
Kawachi H, Kurihara H, Topham PS, Brown D, Shia MA, Orikasa M, Shimizu F, Salant DJ Slit diaphragm-reactive nephritogenic MAb 5-1-6 alters expression of ZO-1 in rat podocytes. Am J Physiol Renal Physiol. 1997;273(6):F984-F993 - PMID: 29586119 - DOI: 10.1152/ajprenal.1997.273.6.F984
Brown D, Lee R, Bonventre JV Redistribution of villin to proximal tubule basolateral membranes after ischemia and reperfusion. Am J Physiol Renal Physiol. 1997;273(6):F1003-F1012 - PMID: 29586118 - DOI: 10.1152/ajprenal.1997.273.6.F1003
Blazer-Yost BL, Paunescu TG, Helman SI, Lee KD, Vlahos CJ Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption. Am J Physiol. 1999;277(3 Pt 1):C531-6 - PMID: 10484339 - DOI: 10.1152/ajpcell.1999.277.3.C531
Beck JS, Breton S, Laprade R, Giebisch G Volume regulation and intracellular calcium in the rabbit proximal convoluted tubule. Am J Physiol. 1991;260(6 Pt 2):F861-7 - PMID: 2058707 - DOI: 10.1152/ajprenal.1991.260.6.F861
Beck JS, Breton S, Mairb Relationship between sodium transport and intracellular ATP in isolated perfused rabbit proximal convoluted tubule. Am J Physiol. 1991;261(4 Pt 2):F634-9 - PMID: 1928376 - DOI: 10.1152/ajprenal.1991.261.4.F634
Beck JS, Breton S, Giebisch G, Laprade R Potassium conductance regulation by pH during volume regulation in rabbit proximal convoluted tubules. Am J Physiol. 1992;263(3 Pt 2):F453-8 - PMID: 1415573 - DOI: 10.1152/ajprenal.1992.263.3.F453
Breton S, Beck JS, Cardinal J, Giebisch G, Laprade R Involvement and source of calcium in volume regulatory decrease of collapsed proximal convoluted tubule. Am J Physiol. 1992;263(4 Pt 2):F656-64 - PMID: 1415737 - DOI: 10.1152/ajprenal.1992.263.4.F656
Macri P, Breton S, Beck JS, Cardinal J, Laprade R Basolateral K+, Cl-, and HCO3- conductances and cell volume regulation in rabbit PCT. Am J Physiol. 1993;264(2 Pt 2):F365-76 - PMID: 8447445 - DOI: 10.1152/ajprenal.1993.264.2.F365
Breton S, Beck JS, Laprade R cAMP stimulates proximal convoluted tubule Na(+)-K(+)-ATPase activity. Am J Physiol. 1994;266(3 Pt 2):F400-10 - PMID: 8160788 - DOI: 10.1152/ajprenal.1994.266.3.F400
Breton S, Alper SL, Gluck SL, Sly WS, Barker JE, Brown D Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice. Am J Physiol. 1995;269(6 Pt 2):F761-74 - PMID: 8594870 - DOI: 10.1152/ajprenal.1995.269.6.F761
Breton S, Marsolais M, Laprade R Hypotonicity increases basolateral taurine permeability in rabbit proximal convoluted tubule. Am J Physiol. 1995;268(4 Pt 2):F595-603 - PMID: 7733316 - DOI: 10.1152/ajprenal.1995.268.4.F595
Breton S, Belachgar F, Marsolais M, Lapointe JY, Laprade R Inhibition of basolateral potassium conductance by taurine in the proximal convoluted tubule. Am J Physiol. 1996;271(5 Pt 2):F1012-9 - PMID: 8945995 - DOI: 10.1152/ajprenal.1996.271.5.F1012
Breton S, Hammar K, Smith PJ, Brown D Proton secretion in the male reproductive tract: involvement of Cl--independent HCO-3 transport. Am J Physiol. 1998;275(4 Pt 1):C1134-42 - PMID: 9755067 - DOI: 10.1152/ajpcell.1998.275.4.C1134
Emma F, Breton S, Morrison R, Wright S, Strange K Effect of cell swelling on membrane and cytoplasmic distribution of pICln. Am J Physiol. 1998;274(6 Pt 1):C1545-51 - PMID: 9696697 - DOI: 10.1152/ajpcell.1998.274.6.C1545
McCarthy JR, Hyland MA, Bruckner C. Synthesis of indaphyrins: meso-tetraarylsecochlorin-based porphyrinoids containing direct o-phenyl-to-beta-linkages. Org Biomol Chem. 2004;2(10):1484-91
McCarthy JR, Bhaumik J, Merbouh N, Weissleder R High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins. Org Biomol Chem. 2009;7(17):3430-6 - PMID: 19675897 - PMCID: PMC2749955 - DOI: 10.1039/b908713c
Mazitschek R, Huwe A, Giannis A Synthesis and biological evaluation of novel fumagillin and ovalicin analogues. Org Biomol Chem. 2005;3(11):2150-4 - PMID: 15917904 - DOI: 10.1039/b503163j
Ueno T, Kaneko K, Katano H, Sato Y, Mazitschek R, Tanaka K, Hattori S, Irie S, Sata T, Ogawa-Goto K Expansion of the trans-Golgi network following activated collagen secretion is supported by a coiled-coil microtubule-bundling protein, p180, on the ER. Exp Cell Res. 2009;316(3):329-40 - PMID: 19932094 - DOI: 10.1016/j.yexcr.2009.11.009
Pastor-Soler NM, Fisher JS, Sharpe R, Hill E, Van Hoek A, Brown D, Breton S Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones. Reproduction. 2009;139(3):613-21 - PMID: 19948840 - PMCID: PMC3773695 - DOI: 10.1530/REP-09-0284
Da Silva N, Cortez-Retamozo V, Reinecker HC, Wildgruber M, Hill E, Brown D, Swirski F, Pittet M, Breton S A dense network of dendritic cells populates the murine epididymis. Reproduction. 2011;141(5):653-63 - PMID: 21310816 - PMCID: PMC3657760 - DOI: 10.1530/REP-10-0493
Shum W, Hill E, Brown D, Breton S Plasticity of basal cells during postnatal development in the rat epididymis. Reproduction. 2013;146(5):455-469 - PMID: 23960170 - PMCID: PMC4106237 - DOI: 10.1530/REP-12-0510
Reimer P, Bader A, Weissleder R Application of a stable cell culture assay for the functional assessment of novel MR contrast agents. Eur Radiol. 1997;7(4):527-31 - PMID: 9204333 - DOI: 10.1007/s003300050197
Salthouse C, Hilderbrand S, Weissleder R, Mahmood U Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008;16 (26):21731-7 - PMID: 19104605 - PMCID: PMC2717740 - DOI: 10.1364/oe.16.021731
Vinegoni C, Bredfeldt J, Marks D, Boppart S Nonlinear optical contrast enhancement for optical coherence tomography. Opt Express. 2004;12:331-41 - PMID: 19471542 - DOI: 10.1364/opex.12.000331
Lee H, Alt C, Pitsillides CM, Puoris'haag M, Lin CP In vivo imaging flow cytometer. Opt Express. 2006;14:7789-800 - PMID: 19529148 - PMCID: PMC2801598 - DOI: 10.1364/oe.14.007789
Tsai CC, Vinegoni C, Weissleder R Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide. Opt Express. 2009;17(24):21723-31 - PMID: 19997414 - PMCID: PMC2805120 - DOI: 10.1364/OE.17.021723
Vinegoni C, Fexon L, Fumene Feruglio P, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R High throughput transmission optical projection tomography using low cost graphics processing unit Opt Express. 2009;17(25):22320-22332 - PMID: 20052155 - PMCID: PMC2805020 - DOI: 10.1364/OE.17.022320
Li C, Pastila RK, Pitsillides C, Runnels JM, Puoris'haag M, Cote D, Lin CP Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence. Opt Express. 2010;18(2):988-99 - PMID: 20173920 - PMCID: PMC3369551 - DOI: 10.1364/OE.18.000988
Razansky RN, Rosenthal A, Mallas G, Razansky D, Jaffer FA, Ntziachristos V Near-infrared fluorescence catheter system for two-dimensional intravascular imaging in vivo. Opt Express. 2010;18(11):11372-81 - PMID: 20588998 - DOI: 10.1364/OE.18.011372
Mansuripur M, Zakharian AR, Lesuffleur A, Oh SH, Jones RJ, Lindquist NC, Im H, Kobyakov A, Moloney JV Plasmonic nano-structures for optical data storage. Opt Express. 2009;17(16):14001-14 - PMID: 19654809 - DOI: 10.1364/oe.17.014001
Lesuffleur A, Im H, Lindquist NC, Lim KS, Oh SH Laser-illuminated nanohole arrays for multiplex plasmonic microarray sensing. Opt Express. 2008;16(1):219-24 - PMID: 18521151 - DOI: 10.1364/oe.16.000219
Curry A, Hwang WL, Wax A Epi-illumination through the microscope objective applied to darkfield imaging and microspectroscopy of nanoparticle interaction with cells in culture. Opt Express. 2006;14(14):6535-42 - PMID: 19516830 - DOI: 10.1364/oe.14.006535
Henry F, Cote D, Randolph M, Rust E, Redmond R, Kochevar I, Lin CP, Winograd J Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg. 2009;123:123S-30S - PMID: 19182671 - DOI: 10.1097/PRS.0b013e318191c5b8
Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects. Sens Actuat B-Chem. 2009;138(2):591-597 - PMID: 20161242 - PMCID: PMC2706141 - DOI: 10.1016/j.snb.2009.02.037
Romero P, Pittet M, Dutoit V, Zippelius A, Lienard D, Lejeune F, Guillaume P, Rimoldi D, Valmori D, Speiser D, Cerottini J Therapeutic cancer vaccines based on molecularly defined human tumor antigens. Vaccine. 2002;20(4):2-7 - PMID: 12477422 - DOI: 10.1016/s0264-410x(02)00380-8
Best SR, Peng S, Juang CM, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery. Vaccine. 2009;27(40):5450-9 - PMID: 19622402 - PMCID: PMC2745985 - DOI: 10.1016/j.vaccine.2009.07.005
Bouley R, Hawthorn G, Russo L, Lin H, Ausiello D, Brown D Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment. Biol Cell. 2006;98(4):215-32 - PMID: 16563128 - DOI: 10.1042/BC20040054
Haller JL, Hyde D, Deliolanis N, de Kleine R, Niedre M, Ntziachristos V Visualization of Pulmonary Inflammation Using Non-invasive Fluorescence Molecular Imaging. J Appl Physiol. 2008;104(3):795-802 - PMID: 18202169 - DOI: 10.1152/japplphysiol.00959.2007
Cazzanelli M, Vinegoni C, Pavesi L Temperature dependence of the photo luminescence of all porous silicon microcavities. J. Appl. Phys. 1999;85;1760-4 J Appl Physiol. 1999;85:1760-4
Speiser D, Pittet M, Guillaume P, Lubenow N, Hoffman E, Cerottini J, Romero P Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring. J Immunother. 2004;27:298-308 - PMID: 15235391 - DOI: 10.1097/00002371-200407000-00006
Hedgire SS, Mino-Kenudson M, Elmi A, Thayer S, Fernandez-Del Castillo C, Harisinghani MG Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation. Int J Nanomedicine. 2014;9:1891-1896 - PMID: 24790431 - PMCID: PMC4000182 - DOI: 10.2147/IJN.S59788
Santos SA, Lukens AK, Coelho L, Nogueira F, Wirth DF, Mazitschek R, Moreira R, Paulo A Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype. Eur J Med Chem. 2015;102:320-333 - PMID: 26295174 - DOI: 10.1016/j.ejmech.2015.07.047
Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging. NMR Biomed. 2008;21(5):453-63 - PMID: 17918777 - PMCID: PMC2629945 - DOI: 10.1002/nbm.1209
Heidt T, Nahrendorf M Multimodal iron oxide nanoparticles for hybrid biomedical imaging. NMR Biomed. 2012;26(7):756-65 - PMID: 23065771 - PMCID: PMC3549036 - DOI: 10.1002/nbm.2872
Framme C, Alt C, Schnell S, Sherwood M, Brinkmann R, Lin CP Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam. Invest Ophth Vis Sci. 2007;48:1782-92 - PMID: 17389512 - DOI: 10.1167/iovs.06-0797
Wei X, Runnels J, Lin C Selective uptake of indocyanine green by reticulocytes in circulation. Invest Ophth Vis Sci. 2003;44:4489-96 - PMID: 14507897 - PMCID: PMC2830078 - DOI: 10.1167/iovs.03-0041
Alt C, Runnels JM, Mortensen LJ, Zaher W, Lin C In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment. Invest Ophthalmol Vis Sci. 2014;55(8):5314-5319 - PMID: 25082884 - DOI: 10.1167/iovs.14-14254
Yip S, Shah K Stem-cell based therapies for brain tumors. Curr Opin Mol Ther. 2008;10:334-42 - PMID: 18683097
Wagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP Angiotensin II Stimulates H-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts. Cell Physiol Biochem. 2011;28(3):513-20 - PMID: 22116365 - PMCID: PMC3709473 - DOI: 10.1159/000335112
Montes M, Rufer N, Appay V, Reynard S, Pittet M, Speiser D, Guillaume P, Cerottini J, Romero P, Leyvraz S Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy. Clin Exp Immunol. 2005;142:292-302 - PMID: 16232216 - PMCID: PMC1809512 - DOI: 10.1111/j.1365-2249.2005.02914.x
Ritz S, Cundall M, Gajewska B, Swirski F, Wiley R, Alvarez D, Coyle A, Stampfli M, Jordana M The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo. Clin Exp Immunol. 2004;138(2):213-20 - PMID: 15498029 - PMCID: PMC1809215 - DOI: 10.1111/j.1365-2249.2004.02618.x
Moffat BA, Reddy GR, McConville P, Hall DE, Chenevert TL, Kopelman RR, Philbert M, Weissleder R, Rehemtulla A, Ross BD A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI Mol Imaging. 2003;2:324-32 - PMID: 14717331 - DOI: 10.1162/15353500200303163
Lin Y, Weissleder R, Tung CH Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging Mol Imaging. 2003;2:87-92 - PMID: 12964306 - DOI: 10.1162/15353500200303121
Josephson L, Mahmood U, Wunderbaldinger P, Tang Y, Weissleder R Pan and sentinel lymph node visualization using a near-infrared fluorescent probe Mol Imaging. 2003;2:18-23 - PMID: 12926234 - DOI: 10.1162/15353500200302154
Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U Miniaturized multichannel near infrared endoscope for mouse imaging Mol Imaging. 2003;2:350-7 - PMID: 14717334 - DOI: 10.1162/15353500200303166
Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R Coded aperture nuclear scintigraphy: a novel small animal imaging technique Mol Imaging. 2002;1:344-53 - PMID: 12926230 - DOI: 10.1162/15353500200221362
Schellenberger EA, Bogdanov A Jr, Hogemann D, Tait J, Weissleder R, Josephson L Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Mol Imaging. 2002;1:102-7 - PMID: 12920851 - DOI: 10.1162/15353500200202103
Ntziachristos, V, Bremer C, Graves EE, Ripoll J, Weissleder R In vivo tomographic imaging of near-infrared fluorescent probes Mol Imaging. 2002;1:82-8 - PMID: 12920848 - DOI: 10.1162/15353500200201121
Kircher MF, Josephson L, Weissleder R Ratio imaging of enzyme activity using dual wavelength optical reporters Mol Imaging. 2003;1:89-95 - PMID: 12920849 - DOI: 10.1162/15353500200201124
Bogdanov A Jr, Matuszewski L, Bremer C, Petrovsky A, Weissleder R Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets Mol Imaging. 2002;1:16-23 - PMID: 12920857 - DOI: 10.1162/15353500200200001
Chen WT, Tung CH, Weissleder R Imaging reactive oxygen species in arthritis. Mol Imaging. 2004;3(3):159-62 - PMID: 15530251 - DOI: 10.1162/15353500200404124
Gillies R, Hoffman J, Lam K, Menkens A, Piwnica-Worms D, Sullivan D, Weissleder R. Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents Mol Imaging. 2005;4:1-6
Wunder A, Schellenberger E, Mahmood U, Bogdanov A Jr, Muller-Ladner U, Weissleder R, Josephson L. Methotrexate-induced accumulation of fluorescent annexin v in collagen-induced arthritis Mol Imaging. 2005;4(1):1-6 - PMID: 15967121 - DOI: 10.1162/15353500200504142
Montet-Abou K, Montet X, Weissleder R, Josephson L. Transfection agent induced nanoparticle cell loading Mol Imaging. 2005;4(3):165-71 - PMID: 16194448 - DOI: 10.1162/15353500200505100
Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R MIPortal: A High Capacity Server for Molecular Imaging Research. Mol Imaging. 2005;4(4):425-31 - PMID: 16285904 - DOI: 10.2310/7290.2005.05136
Chen WT, Khazaie K, Zhang G, Weissleder R, Tung CH Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe Mol Imaging. 2005;4 (1):67-74 - PMID: 15912902
Kelly KA, Clemons PA, Yu AM, Weissleder R High throughput identification of phage-derived imaging agents Mol Imaging. 2006;5(1):24-30 - PMID: 16779967
Sun EY, Josephson L, Weissleder R. Clickable nanoparticles for targeted imaging Mol Imaging. 2006;(5) 2:122-128 - PMID: 16954026
Jaffer F, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials Mol Imaging. 2006;(5) 2 :85-92 - PMID: 16954022
Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V Normalized transillumination of fluorescent proteins in small animals. Mol Imaging. 2006;5 (2):153-9 - PMID: 16954030
Montet-Abou K, Montet X, Weissleder R, Josephson L Cell internalization of magnetic nanoparticles using transfection agents. Mol Imaging. 2007;(6) 1:1-9 - PMID: 17311760
Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging. 2007;6(2):96-107 - PMID: 17445504
Sheth RA, Upadhyay R, Weissleder R, Mahmood U Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007;6(3):147-55 - PMID: 17532881
Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007;6(4):269-76 - PMID: 17711782
Hiller K, Waller C, Nahrendorf M, Bauer W, Jakob P Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging. Mol Imaging. 2006;5(2):115-21 - PMID: 16954025
Runnels J, Zamiri P, Spencer J, Veilleux I, Wei X, Bogdanov AA, Lin CP Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy. Mol Imaging. 2006;5:31-40 - PMID: 16779968 - PMCID: PMC2801601
Wei X, Sipkins D, Pitsillides C, Novak J, Georgakoudi I, Lin C Real-time detection of circulating apoptotic cells by in vivo flow cytometry. Mol Imaging. 2005;4:415-6 - PMID: 16285902 - PMCID: PMC2801924 - DOI: 10.2310/7290.2005.05148
Turner GM, Zacharakis G, Soubret A, Ripoll J, Ntziachristos V. Complete-angle projection diffuse optical tomography by use of early photons Opt Lett. 2005;30(4):409-11 - PMID: 15762444 - DOI: 10.1364/ol.30.000409
Deliolanis N, Lasser T, Hyde D, Soubret A, Ripoll J, Ntziachristos V Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections. Opt Lett. 2007;32(4):382-4 - PMID: 17356660 - DOI: 10.1364/ol.32.000382
Razansky D, Vinegoni C, Ntziachristos V Multispectral photoacoustic imaging of fluorochromes in small animals. Opt Lett. 2007;32(19):2891-3 - PMID: 17909608 - DOI: 10.1364/ol.32.002891
Alt C, Veilleux I, Lee H, Pitsillides CM, Cote D, Lin CP Retinal flow cytometer. Opt Lett. 2007;32:3450-2 - PMID: 18059963 - PMCID: PMC2794483 - DOI: 10.1364/ol.32.003450
Biss DP, Sumorok D, Burns SA, Webb RH, Zhou Y, Bifano TG, Cote D, Veilleux I, Zamiri P, Lin CP In vivo fluorescent imaging of the mouse retina using adaptive optics. Opt Lett. 2007;32:659-61 - PMID: 17308593 - PMCID: PMC2808135 - DOI: 10.1364/ol.32.000659
Razansky D, Vinegoni C, Ntziachristos V Polarization-sensitive optoacoustic tomography of optically diffuse tissues. Opt Lett. 2008;33(20):2308-10 - PMID: 18923605 - DOI: 10.1364/ol.33.002308
Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R Normalized Born ratio for fluorescence optical projection tomography. Opt Lett. 2009;34(3):319-21 - PMID: 19183644 - PMCID: PMC2771918 - DOI: 10.1364/ol.34.000319
Jones G, Marks D, Vinegoni C, Boppart S High-spectral-resolution coherent anti-Stokes Raman scattering with interferometrically detected broadband chirped pulses. Opt Lett. 2006;31(10):1543-5 - PMID: 16642166 - DOI: 10.1364/ol.31.001543
Xu C, Vinegoni C, Ralston T, Luo W, Tan W, Boppart S Spectroscopic spectral-domain optical coherence microscopy. Opt Lett. 2006;31:1079-81 - PMID: 16625909 - DOI: 10.1364/ol.31.001079
Kumar A, Chung E, Raymond S, van de Water J, Shah K, Fukumura D, Jain R, Bacskai B, Boas D Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett. 2009;34(13):2066-8 - PMID: 19572001 - PMCID: PMC2872111 - DOI: 10.1364/ol.34.002066
Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles Opt Lett. 2009;34(17):2566-8 - PMID: 19724491 - PMCID: PMC2749971 - DOI: 10.1364/OL.34.002566
Novak J, Georgakoudi I, Wei X, Prossin A, Lin C In vivo flow cytometer for real-time detection and quantification of circulating cells. Opt Lett. 2004;29:77-9 - PMID: 14719666 - PMCID: PMC2801600 - DOI: 10.1364/ol.29.000077
Lin C, Webb R Fiber-coupled multiplexed confocal microscope. Opt Lett. 2000;25:954-6 - PMID: 18064238 - DOI: 10.1364/ol.25.000954
Swanson EA, Izatt JA, Hee MR, Huang D, Lin CP, Schuman JS, Puliafito CA, Fujimoto JG In vivo retinal imaging by optical coherence tomography. Opt Lett. 1993;18(21):1864-6 - PMID: 19829430 - DOI: 10.1364/ol.18.001864
Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography. Opt Lett. 2010;35(7):1088-90 - PMID: 20364226 - PMCID: PMC2900933 - DOI: 10.1364/OL.35.001088
Ntziachristos V, Weissleder R Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Opt Lett. 2001;26(12):893-5 - PMID: 18040483 - DOI: 10.1364/ol.26.000893
Ntziachristos V, Ripoll J, Weissleder R Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Errata. Opt Lett. 2002;27(18):1652 - PMID: 18026531 - DOI: 10.1364/ol.27.001652
Ripoll J, Nieto-Vesperinas M, Weissleder R, Ntziachristos V Fast analytical approximation for arbitrary geometries in diffuse optical tomography. Opt Lett. 2002;27(7):527-9 - PMID: 18007854 - DOI: 10.1364/ol.27.000527
Ntziachristos V, Ripoll J, Weissleder R Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Opt Lett. 2002;27(5):333-5 - PMID: 18007794 - DOI: 10.1364/ol.27.000333
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. J Crohns Colitis. 2014;8(9):956-63 - PMID: 24559536 - PMCID: PMC4136996 - DOI: 10.1016/j.crohns.2014.01.019
Dubach JM, Vinegoni C, Weissleder R Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging. Opt Lett. 2014;39(15):4482-4485 - PMID: 25078208 - PMCID: PMC4341989 - DOI: 10.1364/OL.39.004482
Sun CC, Vaja V, Chen S, Theurl I, Stepanek A, Brown DE, Cappellini MD, Weiss G, Hong CC, Lin HY, Babitt JL A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats. Nephrol Dial Transplant. 2013;28(7):1733-1743 - PMID: 23345622 - PMCID: PMC3707526 - DOI: 10.1093/ndt/gfs584
Zumbrennen-Bullough K, Babitt JL The iron cycle in CKD: from genetics and experimental models to CKD patients. Nephrol Dial Transplant. 2013;29(2):263-73 - PMID: 24235084 - PMCID: PMC3910345 - DOI: 10.1093/ndt/gft443
Nahrendorf M, Hiller KH, Hu K, Zeijlemaker V, Griswold M, Bauer WR Pacing in high field cardiac magnetic resonance imaging:. Pacing Clin Electrophysiol. 2004;27(5):671-4 - PMID: 15125728 - DOI: 10.1111/j.1540-8159.2004.00506.x
Veilleux I, Spencer JA, Biss DP, C In vivo cell tracking with video rate multimodality laser scanning microscopy IEEE J Sel Top Quant. 2008;14:10:18
Lin CP, Kelly MW, Sibayan SA, Latina MA, Anderson RR Selective Cell Killing by Microparticle Absorption of Pulsed Laser Radiation IEEE J Sel Top Quant. 1999;5:963-8
Vinegoni C, Lee S, Feruglio PF, Weissleder R Advanced Motion Compensation Methods for Intravital Optical Microscopy. IEEE J Sel Top Quant. 2014;20(2):ePub - PMID: 24273405 - PMCID: PMC3832946 - DOI: 10.1109/JSTQE.2013.2279314
Rigosi E, Frasnelli E, Vinegoni C, Antolini R, Anfora G, Vallortigara G, Haase A Searching for anatomical correlates of olfactory lateralization in the honeybee antennal lobes: A morphological and behavioural study. Behav Brain Res.. 2011;221(1):290-4 - PMID: 21402106 - PMCID: PMC3089663 - DOI: 10.1016/j.bbr.2011.03.015
Chung J*, Issadore D*, Ullal A*, Lee K, Weissleder R*, Lee H* Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip Biomicrofluidics. 2013;7(5):54107 - PMID: 24404070 - PMCID: PMC3790798 - DOI: 10.1063/1.4821923
Allport JR, Shinde Patil VR, Weissleder R Murine Neuronal Progenitor Cells are Preferentially Recruited to Tumor Vasculature via alpha(4)-integrin and SDF-1alpha-Dependent Mechanisms. Cancer Biol Ther. 2004;3(9):838-44 - PMID: 15254391 - DOI: 10.4161/cbt.3.9.1036
Shah K. Current Advances in Molecular Imaging of Gene and Cell Therapy for Cancer Cancer Biol Ther. 2005;4(5):518-523 - PMID: 15908803 - DOI: 10.4161/cbt.4.5.1706
Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel D, Grant S, Fisher P Searching for a cure: Gene therapy for glioblastoma. Cancer Biol Ther. 2008;7(9):1335-40 - PMID: 18708757 - DOI: 10.4161/cbt.7.9.6408
Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus W, Ramakrishnan V, Sarkar D, Shah K, Curiel D, Grant S, Fisher P, Dent P MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biol Ther. 2008;7:917-33 - PMID: 18376144 - DOI: 10.4161/cbt.7.6.5928
Wunderbaldinger P, Josephson L, Bremer C, Moore A, Weissleder R Detection of lymph node metastases by contrast-enhanced MRI in an experimental model Magn Reson Med. 2002;47:292-7 - PMID: 11810672 - DOI: 10.1002/mrm.10068
Moore, A, Sun PZ, Cory D, Hogemann D, Weissleder R, Lipes MA MRI of insulitis in autoimmune diabetes Magn Reson Med. 2002;47:751-8 - PMID: 11948737 - DOI: 10.1002/mrm.10110
Kim YR, Savellano MD, Savellano DH, Weissleder R, Bogdanov A Jr Measurement of tumor interstitial volume fraction: Method and implication for drug delivery Magn Reson Med. 2004;52(3):485-94 - PMID: 15334566 - DOI: 10.1002/mrm.20182
Chen JW, Pham W, Weissleder R, Bogdanov A Jr Human myeloperoxidase: A potential target for molecular MR imaging in atherosclerosis. Magn Reson Med. 2004;52(5):1021-8 - PMID: 15508166 - DOI: 10.1002/mrm.20270
Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L. Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle Magn Reson Med. 2005;54(3):718-724 - PMID: 16086367 - DOI: 10.1002/mrm.20617
Hong R, Cima MJ, Weissleder R, Josephson L Magnetic microparticle aggregation for viscosity determination by MR. Magn Reson Med. 2008;59:515-520 - PMID: 18306403 - PMCID: PMC2740908 - DOI: 10.1002/mrm.21526
Schmitt M, Potthast A, Sosnovik DE, Polimeni JR, Wiggins GC, Triantafyllou C, Wald LL A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla. Magn Reson Med. 2008;59:1431-1439 - PMID: 18506789 - PMCID: PMC2548273 - DOI: 10.1002/mrm.21598
Streif J, Nahrendorf M, Hiller K, Waller C, Wiesmann F, Rommel E, Haase A, Bauer W In vivo assessment of absolute perfusion and intracapillary blood volume in the murine myocardium by spin labeling magnetic resonance imaging. Magn Reson Med. 2005;53(3):584-92 - PMID: 15723416 - DOI: 10.1002/mrm.20327
Vonken EJ, Korosoglou G, Yu J, Schar M, Weissleder R, Stuber M On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA). Magn Reson Med. 2009;62(2):314-24 - PMID: 19526511 - PMCID: PMC2742771 - DOI: 10.1002/mrm.22027
Zaharchuk G, Bogdanov AA, Marota JJ, Shimizu-Sasamata M, Weisskoff RM, Kwong KK, Jenkins BG, Weissleder R, Rosen BR Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): a steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction. Magn Reson Med. 1998;40(5):666-78 - PMID: 9797148 - DOI: 10.1002/mrm.1910400504
Mandeville JB, Marota JJ, Kosofsky BE, Keltner JR, Weissleder R, Rosen BR, Weisskoff RM Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med. 1998;39(4):615-24 - PMID: 9543424 - DOI: 10.1002/mrm.1910390415
Mandeville JB, Moore J, Chesler DA, Garrido L, Weissleder R, Weisskoff RM Dynamic liver imaging with iron oxide agents: effects of size and biodistribution on contrast. Magn Reson Med. 1997;37(6):885-90 - PMID: 9178240 - DOI: 10.1002/mrm.1910370613
Harika L, Weissleder R, Poss K, Zimmer C, Papisov MI, Brady TJ MR lymphography with a lymphotropic T1-type MR contrast agent: Gd-DTPA-PGM. Magn Reson Med. 1995;33(1):88-92 - PMID: 7891541 - DOI: 10.1002/mrm.1910330113
Shen T, Weissleder R, Papisov M, Bogdanov A, Brady TJ Monocrystalline iron oxide nanocompounds (MION): physicochemical properties. Magn Reson Med. 1993;29(5):599-604 - PMID: 8505895 - DOI: 10.1002/mrm.1910290504
Weissleder R Target-specific superparamagnetic MR contrast agents. Magn Reson Med. 1991;22(2):209-12; discussion 213-5 - PMID: 1812348 - DOI: 10.1002/mrm.1910220209
Streif JU, Herold V, Szimtenings M, Lanz TE, Nahrendorf M, Wiesmann F, Rommel E, Haase A In vivo time-resolved quantitative motion mapping of the murine myocardium with phase contrast MRI. Magn Reson Med. 2003;49(2):315-21 - PMID: 12541252 - DOI: 10.1002/mrm.10342
Chousterman BG, Swirski FK Innate Response Activator B cells: origins and functions. Int Immunol. 2015;27(10):537-41 - PMID: 25957266 - PMCID: PMC4693688 - DOI: 10.1093/intimm/dxv028
Brown D, Paunescu TG, Breton S, Marshansky V Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking. J Exp Biol. 2009;212(Pt 11):1762-72 - PMID: 19448085 - PMCID: PMC2683016 - DOI: 10.1242/jeb.028803
Shum WW, Da Silva N, Brown D, Breton S Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk. J Exp Biol. 2009;212(Pt 11):1753-61 - PMID: 19448084 - PMCID: PMC2683015 - DOI: 10.1242/jeb.027284
Brown D, Breton S Mitochondria-rich, proton-secreting epithelial cells. J Exp Biol. 1996;199(Pt 11):2345-58 - PMID: 9114500 - DOI: 10.1242/jeb.199.11.2345
Brown D, Smith PJ, Breton S Role of V-ATPase-rich cells in acidification of the male reproductive tract. J Exp Biol. 1997;200(Pt 2):257-62 - PMID: 9050233 - DOI: 10.1242/jeb.200.2.257
Brown D, Breton S H(+)V-ATPase-dependent luminal acidification in the kidney collecting duct and the epididymis/vas deferens: vesicle recycling and transcytotic pathways. J Exp Biol. 2000;203(Pt 1):137-45 - PMID: 10600682 - DOI: 10.1242/jeb.203.1.137
Haase A, Rigosi E, Trona F, Anfora G, Vallortigara G, Antolini R, Vinegoni C In-vivo two-photon imaging of the honey bee antennal lobe. Biomed Opt Express. 2010;2(1):131-8 - PMID: 21326643 - PMCID: PMC3028488 - DOI: 10.1364/BOE.1.000131
Deliolanis NC, Wurdinger T, Pike L, Tannous BA, Breakefield XO, Weissleder R, Ntziachristos V In vivo tomographic imaging of red-shifted fluorescent proteins. Biomed Opt Express. 2011;2(4):887-900 - PMID: 21483611 - PMCID: PMC3072128 - DOI: 10.1364/BOE.2.000887
Bélanger E, Henry FP, Vallée R, Randolph MA, Kochevar IE, Winograd JM, Lin CP, Côté D In vivo evaluation of demyelination and remyelination in a nerve crush injury model. Biomed Opt Express. 2011;2(9):2698-2708 - PMID: 22091449 - PMCID: PMC3184878 - DOI: 10.1364/BOE.2.002698
Wang K, Liu TM, Wu J, Horton NG, Lin CP, Xu C Three-color femtosecond source for simultaneous excitation of three fluorescent proteins in two-photon fluorescence microscopy. Biomed Opt Express. 2012;3(9):1972-7 - PMID: 23024893 - PMCID: PMC3447541 - DOI: 10.1364/BOE.3.001972
Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging. Biomed Opt Express. 2013;4(10):2095-106 - PMID: 24156067 - PMCID: PMC3799669 - DOI: 10.1364/BOE.4.002095
Turcotte R, Alt C, Mortensen LJ, Lin CP Characterization of multiphoton microscopy in the bone marrow following intravital laser osteotomy. Biomed Opt Express. 2014;5(10):3578-88 - PMID: 25360374 - PMCID: PMC4206326 - DOI: 10.1364/BOE.5.003578
Mortensen LJ, Alt C, Turcotte R, Masek M, Liu TM, Côté DC, Xu C, Intini G, Lin CP Femtosecond laser bone ablation with a high repetition rate fiber laser source. Biomed Opt Express. 2014;6(1):32-42 - PMID: 25657872 - PMCID: PMC4317121 - DOI: 10.1364/BOE.6.000032
Remsen LG, McCormick CI, Roman-Goldstein S, Nilaver G, Weissleder R, Bogdanov A, Hellström I, Kroll RA, Neuwelt EA MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis. AJNR Am J Neuroradiol. 1996;17(3):411-8 - PMID: 8881233 - PMCID: PMC8337991
Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006;105:445-54 - PMID: 16961141 - DOI: 10.3171/jns.2006.105.3.445
J.W. Chen, R.L. Belford, R.B. Clarkson Second-Sphere and Outer-Sphere Proton Relaxation of Paramagnetic Contrast Agents J Phys Chem B. 1998;102:2117-2130
J.W. Chen, R.B. Clarkson, R.L. Belford Rotational Dynamics of MRI Paramagnetic Contrast Agents in Viscous Media J Phys Chem B. 1996;100:8093-8100
J.W. Chen, F.P. Auteri, D.E. Budil, R.L. Belford, R.B. Clarkson Use of EPR to Investigate Rotational Dynamics of MRI Paramagnetic Contrast Agents J Phys Chem B. 1994;98:13452
Pulli B, Chen JW Imaging Neuroinflammation - from Bench to Bedside. J Clin Cell Immunol. 2014;5:ePub - PMID: 25525560 - PMCID: PMC4266918 - DOI: 10.4172/2155-9899.1000226
Huang XJ, Im HS, Yarimaga O, Kim JH, Lee DH, Kim HS, Choi YK Direct electrochemistry of uric acid at chemically assembled carboxylated single-walled carbon nanotubes netlike electrode. J Phys Chem B. 2006;110(43):21850-6 - PMID: 17064150 - DOI: 10.1021/jp063749q
Carney BJ, Shah K Migration and fate of therapeutic stem cells in different brain disease models. Neuroscience. 2011;197:37-47 - PMID: 21946010 - PMCID: PMC3589128 - DOI: 10.1016/j.neuroscience.2011.08.063
Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS Genetically engineered T cells to target EGFRvIII expressing glioblastoma. J Neuro-Oncol. 2009;94(3):373-82 - PMID: 19387557 - PMCID: PMC2730985 - DOI: 10.1007/s11060-009-9889-1
Waters JD, Sanchez C, Sahin A, Futalan D, Gonda DD, Scheer JK, Akers J, Palanichamy K, Waterman P, Chakravarti A, Weissleder R, Morse B, Marsh N, Furfine E, Chen CC, Carvajal I, Carter BS CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy. J Neurooncol. 2012;110(1):37-48 - PMID: 22875706 - PMCID: PMC4291475 - DOI: 10.1007/s11060-012-0948-7
Celso CL, Wu JW, Lin CP In vivo imaging of hematopoietic stem cells and their microenvironment. J Biophotonics. 2009;2(11):619-631 - PMID: 19847800 - DOI: 10.1002/jbio.200910072
Feruglio PF, Vinegoni C, Fexon L, Thurber G, Sbarbati A, Weissleder R Noise suppressed, multifocus image fusion for enhanced intraoperative navigation. J Biophotonics. 2012;6(4):363-70 - PMID: 22887724 - PMCID: PMC3779878 - DOI: 10.1002/jbio.201200086
Montet X, Rajopadhye M, Weissleder R. An albumin-activated far-red fluorochrome for in vivo imaging ChemMedChem. 2006;1(1):66-69 - PMID: 16892337 - DOI: 10.1002/cmdc.200500028
Choi YD, McCarthy J, Weissleder R, Tung CH Conjugation of a Photosensitizer to an Oligoarginine-based Cell-penetrating Peptide Increases the Efficacy of Photodynamic Therapy ChemMedChem. 2006;1(4):458-463 - PMID: 16892381 - DOI: 10.1002/cmdc.200500036
Choi Y, Weissleder R, Tung CH Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate. ChemMedChem. 2006;1:698-701 - PMID: 16902920 - DOI: 10.1002/cmdc.200600053
McCarthy JR, Weissleder R Model Systems for Fluorescence and Singlet Oxygen Quenching by Metalloporphyrins. ChemMedChem. 2007;2:360-365 - PMID: 17245681 - DOI: 10.1002/cmdc.200600244
Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R High-Yielding, Two-Step (18) F Labeling Strategy for (18) F-PARP1 Inhibitors. ChemMedChem. 2011;6(3):424-7 - PMID: 21360818 - PMCID: PMC3136544 - DOI: 10.1002/cmdc.201000426
Derbyshire ER, Mazitschek R, Clardy J Characterization of Plasmodium Liver Stage Inhibition by Halofuginone. ChemMedChem. 2012;7(5):844-9 - PMID: 22438279 - PMCID: PMC3359061 - DOI: 10.1002/cmdc.201200045
Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R Platinum Compounds for High-Resolution In Vivo Cancer Imaging. ChemMedChem. 2014;9(6):1131-5 - PMID: 24504646 - PMCID: PMC4037345 - DOI: 10.1002/cmdc.201300502
Keliher EJ, Klubnick JA Reiner T, Mazitschek R, Weissleder R Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes. ChemMedChem. 2014;9(7):1368-73 - PMID: 24596307 - PMCID: PMC4145401 - DOI: 10.1002/cmdc.201300506
Tung CH, Mueller S, Weissleder R Novel branching membrane translocational peptide as gene delivery vector Bioorg Med Chem. 2002;10:3609-14 - PMID: 12213476 - DOI: 10.1016/s0968-0896(02)00248-1
Ho NH, Weissleder R, Tung CH Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate. Bioorg Med Chem. 2006;16:2599-2602 - PMID: 16517162 - DOI: 10.1016/j.bmcl.2006.02.045
Estiu G, West N, Mazitschek R, Greenberg E, Bradner JE, Wiest O On the inhibition of histone deacetylase 8. Bioorg Med Chem. 2010;18(11):4103-4110 - PMID: 20472442 - PMCID: PMC3245874 - DOI: 10.1016/j.bmc.2010.03.080
Sun N, Liu Y, Lee H, Weissleder R, Ham D CMOS RF Biosensor Utilizing Nuclear Magnetic Resonance IEEE J Solid-ST Circ. 2009;44:1629-1643
Sun N, Yoon TJ, Lee H, Andress W, Weissleder R, Ham D Palm NMR and 1-Chip NMR IEEE J Solid-ST Circ. 2011;46(1):342-352
Goergen CJ, Sosnovik DE From Molecules to Myofibers: Multiscale Imaging of the Myocardium. J Cardiovasc Transl Res. 2011;4(4):493-503 - PMID: 21643889 - PMCID: PMC3370890 - DOI: 10.1007/s12265-011-9284-0
Preston MA, Harisinghani MG, Mucci L, Witiuk K, Breau RH Diagnostic tests in urology: magnetic resonance imaging (MRI) for the staging of prostate cancer. BJU Int. 2013;111(3):514-7 - PMID: 23320634 - DOI: 10.1111/j.1464-410X.2012.11447.x
Jayasena V, Brown D, Shtatland T, Gold L In vitro selection of RNA specifically cleaved by bacteriophage T4 RegB endonuclease. Biochemistry-US. 1996;35:2349-56 - PMID: 8652576 - DOI: 10.1021/bi951879b
Senior S, Mans L, VanGuilder H, Kelly K, Hendrich M, Elgren T Catecholase activity associated with copper-S100B. Biochemistry-US. 2003;42:4392-7 - PMID: 12693934 - DOI: 10.1021/bi0205799
Elgren T, Orville A, Kelly K, Lipscomb J, Ohlendorf D, Que L Crystal structure and resonance Raman studies of protocatechuate 3,4-dioxygenase complexed with 3,4-dihydroxyphenylacetate. Biochemistry-US. 1997;36:11504-13 - PMID: 9298971 - DOI: 10.1021/bi970691k
Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model. Pancreas. 2008;37(4):440-4 - PMID: 18953259 - PMCID: PMC3806135 - DOI: 10.1097/MPA.0b013e31817c5113
Spear MA, Breakefield XO, Beltzer J, Schuback D, Weissleder R, Pardo FS, Ladner R Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells Cancer Gene Ther. 2001;8:506-11 - PMID: 11498772 - DOI: 10.1038/sj.cgt.7700334
Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008;1:84-94 - PMID: 18633456 - PMCID: PMC2510813 - DOI: 10.1593/tlo.08118
McDermott S, Thayer SP, Fernandez-Del Castillo C, Mino-Kenudson M, Weissleder R, Harisinghani MG Accurate prediction of nodal status in preoperative patients with pancreatic ductal adenocarcinoma using next-gen nanoparticle. Transl Oncol. 2013;6(6):670-5 - PMID: 24466369 - PMCID: PMC3890701 - DOI: 10.1593/tlo.13400
Moore A, Marecos E, Simonova M, Weissleder R, Bogdanov A Novel gliosarcoma cell line expressing green fluorescent protein: A model for quantitative assessment of angiogenesis. Microvasc Res. 1998;56(3):145-53 - PMID: 9828152 - DOI: 10.1006/mvre.1998.2102
Waller C, Hiller KH, Albrecht M, Hu K, Nahrendorf M, Gattenl Microvascular adaptation to coronary stenosis in the rat heart in vivo: a serial magnetic resonance imaging study. Microvasc Res. 2003;66(3):173-82 - PMID: 14609522 - DOI: 10.1016/s0026-2862(03)00058-x
Hilgendorf I, Swirski FK Making a Difference: Monocyte Heterogeneity in Cardiovascular Disease. Curr Atheroscler Rep. 2012;14(5):450-9 - PMID: 22847772 - PMCID: PMC3436972 - DOI: 10.1007/s11883-012-0274-8
Graves EE, Ripoll J, Weissleder R, Ntziachristos V A submillimeter resolution fluorescence molecular imaging system for small animal imaging Med Phys. 2003;30:901-11 - PMID: 12772999 - DOI: 10.1118/1.1568977
Ntziachristos V, Weissleder R Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media Med Phys. 2002;29:803-9 - PMID: 12033576 - DOI: 10.1118/1.1470209
Turner GM, Soubret A, Ntziachristos V Inversion with early photons. Med Phys. 2007;34(4):1405-11 - PMID: 17500472 - DOI: 10.1118/1.2437103
Razansky D, Ntziachristos V Hybrid photoacoustic fluorescence molecular tomography using finite-element-based inversion. Med Phys. 2007;34(11):4293-301 - PMID: 18072494 - DOI: 10.1118/1.2786866
Allport JR, Weissleder R In vivo imaging of gene and cell therapies Exp Hematol. 2001;29:1237-46 - PMID: 11698119 - DOI: 10.1016/s0301-472x(01)00739-1
Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells. Exp Hematol. 2010;38(4):333-9 - PMID: 20167247 - PMCID: PMC3965294 - DOI: 10.1016/j.exphem.2010.02.003
O'Neill MJ, Weissleder R, Gervais DA, Hahn PF, Mueller PR Tunneled peritoneal catheter placement under sonographic and fluoroscopic guidance in the palliative treatment of malignant ascites AJR Am J Roentgenol. 2001;177:615-8 - PMID: 11517056 - DOI: 10.2214/ajr.177.3.1770615
Harisinghani MG, Saini S, Weissleder R, Hahn PF, Yantiss RK, Tempany C, Wood BJ, Mueller PR MR lymphangiography using ultrasmall superparamagnetic iron oxide in patients with primary abdominal and pelvic malignancies: radiographic-pathologic correlation AJR Am J Roentgenol. 1999;172:1347-51 - PMID: 10227514 - DOI: 10.2214/ajr.172.5.10227514
Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, Weissleder R Ferumoxtran-10-Enhanced MR Lymphangiography: Does Contrast-Enhanced Imaging Alone Suffice for Accurate Lymph Node Characterization? AJR Am J Roentgenol. 2006;186(1):144-8 - PMID: 16357394 - DOI: 10.2214/AJR.04.1287
Saksena M, Harisinghani M, Hahn P, Kim J, Saokar A, King B, Weissleder R Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers. AJR Am J Roentgenol. 2006;187(6):W582-8 - PMID: 17114509 - DOI: 10.2214/AJR.05.0873
Goldberg M, Pivovarov M, Mayo-Smith W, Bhalla M, Blickman J, Bramson R, Boland G, Llewellyn H, Halpern E Application of wavelet compression to digitized radiographs. AJR Am J Roentgenol. 1994;163:463-8 - PMID: 8037051 - DOI: 10.2214/ajr.163.2.8037051
Pandharipande PV, Harisinghani MG, Ozanne EM, Specht MC, Hur C, Lee JM, Gazelle GS Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis. AJR Am J Roentgenol. 2008;191:1308-19 - PMID: 18941062 - DOI: 10.2214/AJR.07.3861
Pandharipande PV, Mora JT, Uppot RN, Goehler A, Braschi M, Halpern EF, Gazelle GS, Harisinghani MG Lymphotropic nanoparticle-enhanced MRI for independent prediction of lymph node malignancy: a logistic regression model. AJR Am J Roentgenol. 2009;193(3):W230-7 - PMID: 19696264 - DOI: 10.2214/AJR.08.2175
Baier ND, Hahn PF, Gervais DA, Samir A, Halpern EF, Mueller PR, Harisinghani MG Fine-needle aspiration biopsy of thyroid nodules: experience in a cohort of 944 patients. AJR Am J Roentgenol. 2009;193(4):1175-9 - PMID: 19770344 - DOI: 10.2214/AJR.08.1840
Gee MS, Kim JY, Gervais DA, Hahn PF, Mueller PR Management of abdominal and pelvic abscesses that persist despite satisfactory percutaneous drainage catheter placement. AJR Am J Roentgenol. 2010;194(3):815-20 - PMID: 20173165 - DOI: 10.2214/AJR.09.3282
Uppot RN, Harisinghani MG, Gervais DA Imaging-guided percutaneous renal biopsy: rationale and approach. AJR Am J Roentgenol. 2010;194(6):1443-9 - PMID: 20489082 - DOI: 10.2214/AJR.10.4427
Sena BF, Stern JP, Pandharipande PV, Klemm B, Bulman J, Pedrosa I, Rofsky NM Screening patients to assess renal function before administering gadolinium chelates: assessment of the choyke questionnaire. AJR Am J Roentgenol. 2010;195(2):424-8 - PMID: 20651199 - PMCID: PMC6247784 - DOI: 10.2214/AJR.09.3803
Cronin CG, Harisinghani MG, Catalano O, Blake MA Multitechnique imaging findings of prolene plug hernia repair. AJR Am J Roentgenol. 2010;195(3):701-6 - PMID: 20729449 - DOI: 10.2214/AJR.09.4142
Callahan RJ, Bogdanov A, Fischman AJ, Brady TJ, Weissleder R Preclinical evaluation and phase I clinical trial of a 99mTc-labeled synthetic polymer used in blood pool imaging. AJR Am J Roentgenol. 1998;171(1):137-43 - PMID: 9648777 - DOI: 10.2214/ajr.171.1.9648777
Weissleder R Can gadolinium be safely given in renal failure? AJR Am J Roentgenol. 1996;167(1):278-9 - PMID: 8659405 - DOI: 10.2214/ajr.167.1.8659405
Lu DS, Saini S, Hahn PF, Goldberg M, Lee MJ, Weissleder R, Gerard B, Halpern E, Cats A T2-weighted MR imaging of the upper part of the abdomen: should fat suppression be used routinely? AJR Am J Roentgenol. 1994;162(5):1095-100 - PMID: 8165989 - DOI: 10.2214/ajr.162.5.8165989
Frank H, Weissleder R, Bogdanov AA, Brady TJ Detection of pulmonary emboli by using MR angiography with MPEG-PL-GdDTPA: an experimental study in rabbits. AJR Am J Roentgenol. 1994;162(5):1041-6 - PMID: 8165978 - DOI: 10.2214/ajr.162.5.8165978
Frank H, Weissleder R, Brady TJ Enhancement of MR angiography with iron oxide: preliminary studies in whole-blood phantom and in animals. AJR Am J Roentgenol. 1994;162(1):209-13 - PMID: 8273667 - DOI: 10.2214/ajr.162.1.8273667
Chew FS, Weissleder R Radiation-induced osteochondroma. AJR Am J Roentgenol. 1991;157(4):792 - PMID: 1892038 - DOI: 10.2214/ajr.157.4.1892038
Chew FS, Weissleder R Mediastinal thymolipoma. AJR Am J Roentgenol. 1991;157(3):468 - PMID: 1872228 - DOI: 10.2214/ajr.157.3.1872228
Weissleder R, Reimer P, Lee AS, Wittenberg J, Brady TJ MR receptor imaging: ultrasmall iron oxide particles targeted to asialoglycoprotein receptors. AJR Am J Roentgenol. 1990;155(6):1161-7 - PMID: 2122660 - DOI: 10.2214/ajr.155.6.2122660
Fretz CJ, Stark DD, Metz CE, Elizondo G, Weissleder R, Shen JH, Wittenberg J, Simeone J, Ferrucci JT Detection of hepatic metastases: comparison of contrast-enhanced CT, unenhanced MR imaging, and iron oxide-enhanced MR imaging. AJR Am J Roentgenol. 1990;155(4):763-70 - PMID: 2119106 - DOI: 10.2214/ajr.155.4.2119106
Hahn PF, Stark DD, Saini S, Rummeny E, Elizondo G, Weissleder R, Wittenberg J, Ferrucci JT The differential diagnosis of ringed hepatic lesions in MR imaging. AJR Am J Roentgenol. 1990;154(2):287-90 - PMID: 2153330 - DOI: 10.2214/ajr.154.2.2153330
Rummeny E, Saini S, Stark DD, Weissleder R, Compton CC, Ferrucci JT Detection of hepatic metastases with MR imaging: spin-echo vs phase-contrast pulse sequences at 0.6 T. AJR Am J Roentgenol. 1989;153(6):1207-11 - PMID: 2683677 - DOI: 10.2214/ajr.153.6.1207
Rummeny E, Saini S, Wittenberg J, Compton C, Hahn PF, Mueller PR, Simeone JF, Stark DD, Weissleder R, Dousset MG MR imaging of liver neoplasms. AJR Am J Roentgenol. 1989;152(3):493-9 - PMID: 2536996 - DOI: 10.2214/ajr.152.3.493
Weissleder R, Elizondo G, Stark DD, Hahn PF, Marfil J, Gonzalez JF, Saini S, Todd LE, Ferrucci JT The diagnosis of splenic lymphoma by MR imaging: value of superparamagnetic iron oxide. AJR Am J Roentgenol. 1989;152(1):175-80 - PMID: 2783273 - DOI: 10.2214/ajr.152.1.175
Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, White DL, Jacobs P, Lewis J Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol. 1989;152(1):167-73 - PMID: 2783272 - DOI: 10.2214/ajr.152.1.167
Rummeny E, Weissleder R, Stark DD, Saini S, Compton CC, Bennett W, Hahn PF, Wittenberg J, Malt RA, Ferrucci JT Primary liver tumors: diagnosis by MR imaging. AJR Am J Roentgenol. 1989;152(1):63-72 - PMID: 2535770 - DOI: 10.2214/ajr.152.1.63
Wittenberg J, Stark DD, Forman BH, Hahn PF, Saini S, Weissleder R, Rummeny E, Ferrucci JT Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR Am J Roentgenol. 1988;151(1):79-84 - PMID: 3259825 - DOI: 10.2214/ajr.151.1.79
Hahn PF, Weissleder R, Stark DD, Saini S, Elizondo G, Ferrucci JT MR imaging of focal splenic tumors. AJR Am J Roentgenol. 1988;150(4):823-7 - PMID: 3279735 - DOI: 10.2214/ajr.150.4.823
Weissleder R, Saini S, Stark DD, Wittenberg J, Ferrucci JT Dual-contrast MR imaging of liver cancer in rats. AJR Am J Roentgenol. 1988;150(3):561-6 - PMID: 3257610 - DOI: 10.2214/ajr.150.3.561
Weissleder R, Hahn PF, Stark DD, Rummeny E, Saini S, Wittenberg J, Ferrucci JT MR imaging of splenic metastases: ferrite-enhanced detection in rats. AJR Am J Roentgenol. 1987;149(4):723-6 - PMID: 3498320 - DOI: 10.2214/ajr.149.4.723
Cronin CG, Gervais DA, Hahn PF, Arellano R, Guimaraes AR, Mueller PR Treatment of Deep Intramuscular and Musculoskeletal Abscess: Experience With 99 CT-Guided Percutaneous Catheter Drainage Procedures. AJR Am J Roentgenol. 2011;196(5):1182-1188 - PMID: 21512090 - DOI: 10.2214/AJR.09.4082
Gee MS, Nimkin K, Hsu M, Israel EJ, Biller JA, Katz AJ, Mino-Kenudson M, Harisinghani MG Prospective Evaluation of MR Enterography as the Primary Imaging Modality for Pediatric Crohn Disease Assessment. AJR Am J Roentgenol. 2011;197(1):224-31 - PMID: 21701034 - PMCID: PMC3711021 - DOI: 10.2214/AJR.10.5970
Duigenan S, Gee MS Imaging of pediatric patients with inflammatory bowel disease. AJR Am J Roentgenol. 2012;199(4):907-15 - PMID: 22997386 - DOI: 10.2214/AJR.11.7966
Elmi A, Tabatabaei S, Talab SS, Hedgire SS, Cao K, Harisinghani M Incidental findings at initial imaging workup of patients with prostate cancer: clinical significance and outcomes. AJR Am J Roentgenol. 2012;199(6):1305-11 - PMID: 23169722 - DOI: 10.2214/AJR.11.8417
Rajesh A, Cloud G, Harisinghani MG Improving the quality of manuscript reviews: impact of introducing a structured electronic template to submit reviews. AJR Am J Roentgenol. 2013;200(1):20-3 - PMID: 23255737 - DOI: 10.2214/AJR.11.8299
Gunn AJ, Seethamraju RT, Hedgire S, Elmi A, Daniels GH, Harisinghani MG Imaging Behavior of the Normal Adrenal on Ferumoxytol-Enhanced MRI: Preliminary Findings. AJR Am J Roentgenol. 2013;201(1):117-21 - PMID: 23789664 - DOI: 10.2214/AJR.12.9357
Hedgire SS, McDermott S, Borczuk D, Elmi A, Saini S, Harisinghani MG The Spectrum of IgG4-Related Disease in the Abdomen and Pelvis. AJR Am J Roentgenol. 2013;201(1):14-22 - PMID: 23789654 - DOI: 10.2214/AJR.12.9995
Dhyani M, Anupindi SA, Ayyala R, Hahn PF, Gee MS Defining an imaging algorithm for noncystic splenic lesions identified in young patients. AJR Am J Roentgenol. 2013;201(6):W893-9 - PMID: 24261396 - DOI: 10.2214/AJR.12.10105
Marcus C, Whitworth PW, Surasi DS, Pai SI, Subramaniam RM PET/CT in the management of thyroid cancers. AJR Am J Roentgenol. 2014;202(6):1316-29 - PMID: 24848831 - DOI: 10.2214/AJR.13.11673
Robbins CS, Swirski FK Newly discovered innate response activator B cells: crucial responders against microbial sepsis. Expert Rev Clin Immunol. 2012;8(5):405-7 - PMID: 22882214 - DOI: 10.1586/eci.12.32
Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V. Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography J Biomed Opt. 2005;10(4):44019 - PMID: 16178652 - DOI: 10.1117/1.1993427
Ntziachristos V, Turner G, Dunham J, Windsor S, Soubret A, Ripoll J, Shih HA Planar fluorescence imaging using normalized data. J Biomed Opt. 2005;10(6):64007 - PMID: 16409072 - DOI: 10.1117/1.2136148
Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy. J Biomed Opt. 2006;11(2):21009 - PMID: 16674184 - DOI: 10.1117/1.2186337
Hsiao JK, Law B, Weissleder R, Tung CH In-vivo imaging of tumor associated urokinase-type plasminogen activator activity. J Biomed Opt. 2006;11(3):34013 - PMID: 16822063 - DOI: 10.1117/1.2204029
Niedre MJ, Turner GM, Ntziachristos V Time-resolved imaging of optical coefficients through murine chest cavities. J Biomed Opt. 2006;11(6):064017 - PMID: 17212540 - DOI: 10.1117/1.2400702
Kim P, Puoris'haag M, Cote D, Lin CP, Yun SH In vivo confocal and multiphoton microendoscopy. J Biomed Opt. 2008;13(1):010501 - PMID: 18315346 - PMCID: PMC2752311 - DOI: 10.1117/1.2839043
Deliolanis NC, Kasmieh R, Wurdinger T, Tannous BA, Shah K, Ntziachristos V Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications. J Biomed Opt. 2008;13(4):044008 - PMID: 19021336 - PMCID: PMC2749214 - DOI: 10.1117/1.2967184
Deliolanis N, Dunham J, Wurdinger T, Figueiredo J, Bakhos T, Ntziachristos V In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography. J Biomed Opt. 2009;14(3):030509 - PMID: 19566290 - PMCID: PMC2881930 - DOI: 10.1117/1.3149854
Lee H, Alt C, Pitsillides C, Lin CP Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration. J Biomed Opt. 2007;12:064034 - PMID: 18163850 - DOI: 10.1117/1.2804078
Boutrus S, Greiner C, Hwu D, Chan M, Kuperwasser C, Lin CP, Georgakoudi I Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells. J Biomed Opt. 2007;12:020507 - PMID: 17477705 - PMCID: PMC2798734 - DOI: 10.1117/1.2722733
Roegener J, Brinkmann R, Lin CP Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells. J Biomed Opt. 2004;9:367-71 - PMID: 15065904 - DOI: 10.1117/1.1646413
Alt C, Framme C, Schnell S, Lee H, Brinkmann R, Lin CP Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner. J Biomed Opt. 2006;10(6):064014 - PMID: 16409079 - DOI: 10.1117/1.2136314
Calfon MA, Vinegoni C, Ntziachristos V, Jaffer FA Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques. J Biomed Opt. 2010;15(1):011107 - PMID: 20210433 - PMCID: PMC3188610 - DOI: 10.1117/1.3280282
Runnels JM*, Carlson AL*, Pitsillides C, Thompson B, Wu J, Spencer JA, Kohler JMJ, Azab AK, Moreau AS, Rodig SJ, Kung AL, Anderson KC, Ghobrial IM, Lin CP Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy J Biomed Opt. 2011;16(1):011006 - PMID: 21280893 - PMCID: PMC3033873 - DOI: 10.1117/1.3520571
Hajjarian Z, Xi J, Jaffer FA, Tearney GJ, Nadkarni SK Intravascular laser speckle imaging catheter for the mechanical evaluation of the arterial wall. J Biomed Opt. 2011;16(2):026005 - PMID: 21361689 - PMCID: PMC3056316 - DOI: 10.1117/1.3533322
Imitola J, Cote D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011;16(2):021109 - PMID: 21361672 - PMCID: PMC3061329 - DOI: 10.1117/1.3533312
Zettergren E, Vickers D, Runnels J, Murthy SK, Lin CP, Niedre M Instrument for fluorescence sensing of circulating cells with diffuse light in mice in vivo. J Biomed Opt. 2012;17(3):037001 - PMID: 22502573 - PMCID: PMC3380949 - DOI: 10.1117/1.JBO.17.3.037001
Kim Y, Higgins JM, Dasari RR, Suresh S, Park Y Anisotropic light scattering of individual sickle red blood cells. J Biomed Opt. 2012;17(4):040501 - PMID: 22559667 - PMCID: PMC3602817 - DOI: 10.1117/1.JBO.17.4.040501
Lee S, Vinegoni C, Feruglio PF, Weissleder R Improved intravital microscopy via synchronization of respiration and holder stabilization. J Biomed Opt. 2012;17(9):96018-1 - PMID: 23085919 - PMCID: PMC3449295 - DOI: 10.1117/1.JBO.17.9.096018
Achilefu S, Contag CH, Savitsky AP, Weissleder R Chemical and Genetic Sensors in Biomedical Research. J Biomed Opt. 2005;10(4):41201 - PMID: 23171967
Pestana N, Mortensen LJ, Runnels JP, Vickers D, Murthy SK, Lin CP, Niedre M Improved diffuse fluorescence flow cytometer prototype for high sensitivity detection of rare circulating cells in vivo. J Biomed Opt. 2013;18(7):77002 - PMID: 23831714 - PMCID: PMC3702234 - DOI: 10.1117/1.JBO.18.7.077002
Tung CH Fluorescent peptide probes for in vivo diagnostic imaging. Biopolymers. 2004;76(5):391-403 - PMID: 15389488 - DOI: 10.1002/bip.20139
Liu X, Nielsen GP, Rosenberg AE, Waterman PR, Yang W, Choy E, Sassi S, Yang S, Harmon DC, Yang C, Schwab JH, Kobayashi E, Mankin HJ, Xavier R, Weissleder R, Duan Z, Hornicek FJ Establishment and characterization of a novel chordoma cell line: CH22. J Orthop Res. 2012;30(10):1666-73 - PMID: 22504929 - DOI: 10.1002/jor.22113
Querol Sans M*, Chen JW*, Weissleder R, Bogdanov AA Myeloperoxidase Activity Imaging Using (67)Ga Labeled Substrate. Mol Imaging Biol. 2005;7(6):403-10 - PMID: 16292477 - DOI: 10.1007/s11307-005-0020-5
Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging. Mol Imaging Biol. 2006;8(4):201-7 - PMID: 16791746 - DOI: 10.1007/s11307-006-0043-6
Guimaraes AR, Ross R, Figuereido JL, Waterman P, Weissleder R MRI with Magnetic Nanoparticles Monitors Downstream Anti-Angiogenic Effects of mTOR Inhibition. Mol Imaging Biol. 2011;13(2):314-20 - PMID: 20559742 - DOI: 10.1007/s11307-010-0357-2
Thurber GM, Weissleder R Quantitating Antibody Uptake In Vivo: Conditional Dependence on Antigen Expression Levels. Mol Imaging Biol. 2011;13(4):623-32 - PMID: 20809210 - PMCID: PMC3000888 - DOI: 10.1007/s11307-010-0397-7
Saxena A, Kessinger CW, Thompson B, McCarthy JR, Iwamoto Y, Lin CP, Jaffer FA High-Resolution Optical Mapping of Inflammatory Macrophages Following Endovascular Arterial Injury. Mol Imaging Biol. 2013;15(3):282-9 - PMID: 23090852 - PMCID: PMC3650124 - DOI: 10.1007/s11307-012-0599-2
Lartey FM, Ahn GO, Shen B, Cord KT, Smith T, Chua JY, Rosenblum S, Liu H, James ML, Chernikova S, Lee SW, Pisani LJ, Tirouvanziam R, Chen JW, Palmer TD, Chin FT, Guzman R, Graves EE, Loo BW PET Imaging of Stroke-Induced Neuroinflammation in Mice Using [(18)F]PBR06. Mol Imaging Biol. 2013;16(1):109-17 - PMID: 23836504 - PMCID: PMC4141125 - DOI: 10.1007/s11307-013-0664-5
Lartey FM, Ahn GO, Ali R, Rosenblum S, Miao Z, Arksey N, Shen B, Colomer MV, Rafat M, Liu H, Alejandre-Alcazar MA, Chen JW, Palmer T, Chin FT, Guzman R, Loo BW, Graves E The Relationship Between Serial [(18) F]PBR06 PET Imaging of Microglial Activation and Motor Function Following Stroke in Mice. Mol Imaging Biol. 2014;16(6):821-9 - PMID: 24865401 - PMCID: PMC4237703 - DOI: 10.1007/s11307-014-0745-0
Carlucci G, Carney B, Brand C, Kossatz S, Irwin CP, Carlin SD, Keliher EJ, Weber W, Reiner T Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma. Mol Imaging Biol. 2015;17(6):848-55 - PMID: 25895168 - PMCID: PMC4609241 - DOI: 10.1007/s11307-015-0858-0
Davis RW, Eggleston H, Johnson F, Nahrendorf M, Bock PE, Peterson T, Panizzi P In Vivo Tracking of Streptococcal Infections of Subcutaneous Origin in a Murine Model. Mol Imaging Biol. 2015;17(6):793-801 - PMID: 25921659 - PMCID: PMC4807872 - DOI: 10.1007/s11307-015-0856-2
Mazitschek R, Baumhof P, Giannis A Peptidomimetics and angiogenesis. Mini Rev Med Chem. 2002;2(5):491-506 - PMID: 12370049 - DOI: 10.2174/1389557023405710
Spear MA, Herrlinger U, Rainov N, Pechan P, Weissleder R, Breakefield XO Targeting gene therapy vectors to CNS malignancies. J Neurovirol. 1998;4(2):133-47 - PMID: 9584951 - DOI: 10.3109/13550289809114514
Chang K, Jaffer F Advances in fluorescence imaging of the cardiovascular system. J Nucl Cardiol. 2008;15(3):417-28 - PMID: 18513648 - DOI: 10.1016/j.nuclcard.2008.03.001
Panizzi P, Stone JR, Nahrendorf M Endocarditis and molecular imaging. J Nucl Cardiol. 2014;21(3):486-95 - PMID: 24797384 - PMCID: PMC4106242 - DOI: 10.1007/s12350-014-9902-8
Lin JR, Wang H, Collins AB, Stone JR Tongue necrosis and systemic vascular amyloidosis. Hum Pathol. 2011;42(5):734-737 - PMID: 21236468 - DOI: 10.1016/j.humpath.2010.08.011
Bouley R, Hasler U, Lu HA, Nunes P, Brown D Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus. Semin Nephrol. 2008;28:266-78 - PMID: 18519087 - PMCID: PMC2494582 - DOI: 10.1016/j.semnephrol.2008.03.010
Brown D Aquaporins and vasopressin signaling in kidney health and disease: introduction. Semin Nephrol. 2008;28:215-6 - PMID: 18519082 - DOI: 10.1016/j.semnephrol.2008.03.001
Lin HY Transforming Growth Factor-β and the Kidney Revisited: Introduction. Semin Nephrol. 2012;32(3):225-7 - PMID: 22835452 - DOI: 10.1016/j.semnephrol.2012.04.010
Yeung CH, Breton S, Setiawan I, Xu Y, Lang F, Cooper TG Increased luminal pH in the epididymis of infertile c-ros knockout mice and the expression of sodium-hydrogen exchangers and vacuolar proton pump H+-ATPase. Mol Reprod Dev. 2004;68(2):159-68 - PMID: 15095336 - DOI: 10.1002/mrd.20067
Kim B, Breton S Localization of the gap junction protein, connexin 43, and E-cadherin/Cadherin-1 in the proximal mouse epididymis. Mol Reprod Dev. 2015;82(10):723 - PMID: 26331361
Ho NH, Weissleder R, Tung CH Development of water-soluble far-red fluorogenic dyes for enzyme sensing Tetrahedron. 2006;62:578-585
McCarthy JR, Capetta SH, Melfi PJ, Bruckner C Use of Ag(II) as a removable ion in porphyrin chemistry: Diol cleavage products of [meso-tetraphenyl-2,3-diolchlorinato]Ag(II) Tetrahedron. 2003;59:9137-46
Boiselle PM, Patz EF, Vining DJ, Weissleder R, Shepard JA, McLoud TC Imaging of mediastinal lymph nodes: CT, MR, and FDG PET. Radiographics. 1998;18(5):1061-9 - PMID: 9747607 - DOI: 10.1148/radiographics.18.5.9747607
Sahani DV, Bonaffini PA, Catalano OA, Guimaraes AR, Blake MA State-of-the-Art PET/CT of the Pancreas: Current Role and Emerging Indications. Radiographics. 2012;32(4):1133-58 - PMID: 22786999 - PMCID: PMC6939848 - DOI: 10.1148/rg.324115143
Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Arch Pathol Lab Med. 2009;133(12):1949-53 - PMID: 19961250 - PMCID: PMC3694269 - DOI: 10.1043/1543-2165-133.12.1949
Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA Computational pathology: an emerging definition. Arch Pathol Lab Med. 2014;138(9):1133-8 - PMID: 25171694 - DOI: 10.5858/arpa.2014-0034-ED
Bogdanov A, Wright SC, Marecos EM, Bogdanova A, Martin C, Petherick P, Weissleder R A long-circulating co-polymer in "passive targeting" to solid tumors. J Drug Target. 1997;4(5):321-30 - PMID: 9169989 - DOI: 10.3109/10611869708995848
Salthouse CD, Weissleder R, Mahmood U Development of a Time Domain Fluorimeter for Fluorescent Lifetime Multiplexing Analysis. IEEE T Biomed Circuits Syst. 2008;2(3):204-211 - PMID: 19830273 - PMCID: PMC2760943 - DOI: 10.1109/TBCAS.2008.2003195
Merkulova M, McKee M, Dip PV, Gruber G, Marshansky V N-terminal domain of the V-ATPase a2-subunit displays integral membrane protein properties. Protein Sci. 2010;19(10):1850-1862 - PMID: 20669186 - PMCID: PMC2998721 - DOI: 10.1002/pro.470
Smith TB, Cortez-Retamozo V, Grigoryeva LS, Hill E, Pittet MJ, Da Silva N Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis. Andrology. 2014;2(5):755-62 - PMID: 25082073 - PMCID: PMC4396827 - DOI: 10.1111/j.2047-2927.2014.00251.x
Soubret A, Ntziachristos V Fluorescence molecular tomography in the presence of background fluorescence. Phys Med Biol. 2006;51:3983-4001 - PMID: 16885619 - DOI: 10.1088/0031-9155/51/16/007
Razansky D, Vinegoni C, Ntziachristos V Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography. Phys Med Biol. 2009;54:2769-2777 - PMID: 19369709 - DOI: 10.1088/0031-9155/54/9/012
Fumene Feruglio P, Vinegoni C, Gros J, Sbarbati A, Weissleder R Block matching 3D random noise filtering for absorption optical projection tomography. Phys Med Biol. 2010;55(18):5401-5415 - PMID: 20736500 - PMCID: PMC2934766 - DOI: 10.1088/0031-9155/55/18/009
Zettergren E, Swamy T, Runnels J, Lin CP, Niedre M Tomographic sensing and localization of fluorescently labeled circulating cells in mice in vivo. Phys Med Biol. 2012;57(14):4627-41 - PMID: 22750660 - PMCID: PMC3555500 - DOI: 10.1088/0031-9155/57/14/4627
Razansky D, Deliolanis N, Vinegoni C, Ntziachristos V Deep Tissue Optical and Optoacoustic Molecular Imaging Technologies for Small Animal Research and Drug Discovery. Curr Pharm Biotechnol. 2012;13(4):504-22 - PMID: 22216767 - DOI: 10.2174/138920112799436258
Papisov M, Weissleder R Drug delivery to lymphatic tissue. Crit Rev Ther Drug Carrier Syst. 1996;13(1-2):57-84 - PMID: 8853959
Wiesmann F, Herold V, Streiff JU, Nahrendorf M, Neubauer S, Rommel E, Haase A Novel insights into LV remodeling after murine myocardial infarction by in vivo magnetic resonance tissue velocity mapping. Int J Cardiovasc Imaging. 2004;20(4):289-91 - PMID: 15529911 - DOI: 10.1023/b:caim.0000041945.64887.f4
Joseph P, Ishai A, MacNabb M, Abdelbaky A, Lavender ZR, Ruskin J, Nahrendorf M, Tawakol A Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation. Int J Cardiovasc Imaging. 2015;32(1):113-119 - PMID: 26411879 - PMCID: PMC4730873 - DOI: 10.1007/s10554-015-0766-z
Thurber GM, Figueiredo JL, Weissleder R Detection limits of intraoperative near infrared imaging for tumor resection. J Surg Oncol. 2010;102(7):758-64 - PMID: 20872807 - PMCID: PMC3758114 - DOI: 10.1002/jso.21735
Gomez NR, Kouniavsky G, Tsai HL, Somervell H, Pai SI, Tufano RP, Umbricht C, Kowalski J, Dackiw AP, Zeiger MA Tumor size and presence of calcifications on ultrasonography are pre-operative predictors of lymph node metastases in patients with papillary thyroid cancer. J Surg Oncol. 2011;104(6):613-6 - PMID: 21744345 - DOI: 10.1002/jso.21891
Gutiérrez OM, Sun CC, Chen W, Babitt JL, Lin HY Statement of Concern about a Commercial Assay Used to Measure Soluble Hemojuvelin in Humans. Am J Nephrol. 2012;36(4):332-333 - PMID: 23006450 - DOI: 10.1159/000342519
Breton S, Tyszkowski R, Sabolic I, Brown D Postnatal development of H+ ATPase (proton-pump)-rich cells in rat epididymis. Histochem Cell Biol. 1999;111(2):97-105 - PMID: 10090570 - DOI: 10.1007/s004180050339
Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP Mode of Childbirth and Long-Term Outcomes in Women with Inflammatory Bowel Diseases. Dig Dis Sci. 2014;60(2):471-7 - PMID: 25213079 - PMCID: PMC4304947 - DOI: 10.1007/s10620-014-3353-6
Corey KE, Kartoun U, Zheng H, Shaw SY Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record. Dig Dis Sci. 2015;61(3):913-9 - PMID: 26537487 - PMCID: PMC4761309 - DOI: 10.1007/s10620-015-3952-x
Marshansky V The V-ATPase a2-subunit as a putative endosomal pH-sensor. Biochem Soc T. 2007;35:1092-9 - PMID: 17956287 - DOI: 10.1042/BST0351092
Kelly KA, Reynolds F, Weissleder R, Josephson L Fluorescein isothiocyanate-hapten immunoassay for determination of peptide-cell interactions. Anal Biochem. 2004;330(2):181-5 - PMID: 15203322 - DOI: 10.1016/j.ab.2004.02.035
Law B, Hsiao JK, Bugge TH, Weissleder R, Tung CH. Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples Anal Biochem. 2005;338(1):151-158 - PMID: 15707946 - DOI: 10.1016/j.ab.2004.11.039
Laha M, Panizzi P, Nahrendorf M, Bock PE Engineering streptokinase for generation of active site-labeled plasminogen analogs. Anal Biochem. 2011;415(2):105-15 - PMID: 21570944 - PMCID: PMC3114107 - DOI: 10.1016/j.ab.2011.04.025
Shtatland T, Guettler D, Kossodo M, Pivovarov M, Weissleder R PepBank - a database of peptides based on sequence text mining and public peptide data sources. BMC Bioinformatics. 2007;8(1):280 - PMID: 17678535 - PMCID: PMC1976427 - DOI: 10.1186/1471-2105-8-280
Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R Enhancing navigation in biomedical databases by community voting and database-driven text classification. BMC Bioinformatics. 2009;10(1):317 - PMID: 19799796 - PMCID: PMC2768718 - DOI: 10.1186/1471-2105-10-317
Rabkin-Aikawa E, Mayer J, Schoen F Heart valve regeneration. Adv Biochem Eng Biot. 2005;94:141-79 - PMID: 15915872 - DOI: 10.1007/b100003
Schima W, Saini S, Petersein J, Weissleder R, Harisinghani M, Mayo-Smith W, Hahn PF MR imaging of the liver with Gd-BOPTA: quantitative analysis of T1-weighted images at two different doses J Magn Reson Imaging. 1999;10:80-3 - PMID: 10398981 - DOI: 10.1002/(sici)1522-2586(199907)10:1<80::aid-jmri11>3.0.co;2-s
Hofmann, B, Bogdanov A Jr, Marecos E, Ebert W, Semmler W, Weissleder R Mechanism of gadophrin-2 accumulation in tumor necrosis J Magn Reson Imaging. 1999;9:336-41 - PMID: 10077034 - DOI: 10.1002/(sici)1522-2586(199902)9:2<336::aid-jmri28>3.0.co;2-3
Enochs WS, Harsh G, Hochberg F, Weissleder R Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent J Magn Reson Imaging. 1999;9:228-32 - PMID: 10077018 - DOI: 10.1002/(sici)1522-2586(199902)9:2<228::aid-jmri12>3.0.co;2-k
Korosoglou G, Tang L, Kedziorek D, Cosby K, Gilson WD, Vonken EJ, Schar M, Sosnovik D, Kraitchman DL, Weiss RG, Weissleder R, Stuber M Positive contrast MR-lymphography using inversion recovery with ON-resonant water suppression (IRON). J Magn Reson Imaging. 2008;27(5):1175-1180 - PMID: 18425827 - PMCID: PMC2740932 - DOI: 10.1002/jmri.21337
Nahrendorf M, Wiesmann F, Hiller K, Hu K, Waller C, Ruff J, Lanz T, Neubauer S, Haase A, Ertl G, Bauer W Serial cine-magnetic resonance imaging of left ventricular remodeling after myocardial infarction in rats. J Magn Reson Imaging. 2001;14(5):547-55 - PMID: 11747006 - DOI: 10.1002/jmri.1218
Hamilton AM, Rogers KA, Belisle AJ, Ronald JA, Rutt BK, Weissleder R, Boughner DR Early identification of aortic valve sclerosis using iron oxide enhanced MRI. J Magn Reson Imaging. 2010;31(1):110-6 - PMID: 20027578 - PMCID: PMC5638659 - DOI: 10.1002/jmri.22008
Reimer P, Bader A, Weissleder R Preclinical assessment of hepatocyte-targeted MR contrast agents in stable human liver cell cultures. J Magn Reson Imaging. 1998;8(3):687-9 - PMID: 9626887 - DOI: 10.1002/jmri.1880080326
Moore A, Weissleder R, Bogdanov A Uptake of dextran-coated monocrystalline iron oxides in tumor cells and macrophages. J Magn Reson Imaging. 1998;7(6):1140-5 - PMID: 9400860 - DOI: 10.1002/jmri.1880070629
Weissleder R, Cheng HC, Bogdanova A, Bogdanov A Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging. 1997;7(1):258-63 - PMID: 9039625 - DOI: 10.1002/jmri.1880070140
Stiskal M, Schwickert HC, Demsar F, Roberts TP, Szolar D, Weissleder R, Brasch RC Contrast enhancement in experimental radiation-induced liver injury: comparison of hepatocellular and reticuloendothelial particulate contrast agents. J Magn Reson Imaging. 1997;6(2):286-90 - PMID: 9132091 - DOI: 10.1002/jmri.1880060205
Reimer P, Saini S, Kwong KK, Cohen MS, Weissleder R, Brady TJ Dynamic gadolinium-enhanced echo-planar MR imaging of the liver: effect of pulse sequence and dose on enhancement. J Magn Reson Imaging. 1994;4(3):331-5 - PMID: 8061430 - DOI: 10.1002/jmri.1880040318
Enochs WS, Weissleder R MR imaging of the peripheral nervous system. J Magn Reson Imaging. 1994;4(3):251-7 - PMID: 7520307 - DOI: 10.1002/jmri.1880040306
Weissleder R, Wang YM, Papisov M, Bogdanov A, Schaffer B, Brady TJ, Wittenberg J Polymeric contrast agents for MR imaging of adrenal glands. J Magn Reson Imaging. 1993;3(1):93-7 - PMID: 8428107 - DOI: 10.1002/jmri.1880030116
Reimer P, Kwong KK, Weisskoff R, Cohen MS, Brady TJ, Weissleder R Dynamic signal intensity changes in liver with superparamagnetic MR contrast agents. J Magn Reson Imaging. 1992;2(2):177-81 - PMID: 1562768 - DOI: 10.1002/jmri.1880020210
Weissleder R, Papisov M Pharmaceutical iron oxides for MR imaging J Magn Reson Imaging. 1992;4:1-6
Sosnovik DE, Dai G, Nahrendorf M, Rosen BR, Seethamraju R Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm. J Magn Reson Imaging. 2007;26(2):279-87 - PMID: 17654729 - DOI: 10.1002/jmri.20966
Streif JU, Hiller KH, Waller C, Nahrendorf M, Wiesmann F, Bauer WR, Rommel E, Haase A In vivo assessment of absolute perfusion in the murine skeletal muscle with spin labeling MRI. Magnetic resonance imaging. J Magn Reson Imaging. 2003;17(1):147-52 - PMID: 12500285 - DOI: 10.1002/jmri.10229
Gee MS, Harisinghani MG MRI in patients with inflammatory bowel disease. J Magn Reson Imaging. 2011;33(3):527-534 - PMID: 21512607 - PMCID: PMC3078716 - DOI: 10.1002/jmri.22504
Osborn EA, Jaffer FA Advances in molecular imaging of atherosclerotic vascular disease. Curr Opin Cardiol. 2008;23:620-8 - PMID: 18830079 - PMCID: PMC3984946 - DOI: 10.1097/HCO.0b013e328310fc7e
Vinegoni C, Karlsson M, Petersson M, Sunnerud H Statistics of polarization-dependent loss in a recirculating loop. J Lightwave Technol. 2004;22:968-76
Wegmuller M, Oberson P, Guinnard O, Huttner B, Guinnard L, Vinegoni C, Gisin N Distributed gain measurements in Er-doped fibers with high resolution and accuracy using an Optical Frequency Domain Reflectometer. J Lightwave Technol. 2000;18:2127-32
Low A, O'Donnell C, Kathiresan S, Everett B, Chae C, Shaw S, Ellinor P, MacRae C Aging syndrome genes and premature coronary artery disease. BMC Med Genet. 2005;6:38 - PMID: 16262891 - PMCID: PMC1289285 - DOI: 10.1186/1471-2350-6-38
Neuwelt EA, Weissleder R, Nilaver G, Kroll RA, Roman-Goldstein S, Szumowski J, Pagel MA, Jones RS, Remsen LG, McCormick CI Delivery of virus-sized iron oxide particles to rodent CNS neurons. Neurosurgery. 1994;34(4):777-84 - PMID: 8008188 - DOI: 10.1227/00006123-199404000-00048
Shum WW, Ruan YC, Da Silva N, Breton S Establishment of Cell-Cell Crosstalk in the Epididymis: Control of Luminal Acidification. J Androl. 2011;32(6):576-86 - PMID: 21441423 - PMCID: PMC3753098 - DOI: 10.2164/jandrol.111.012971
Da Silva N, Shum WW, Breton S Regulation of vacuolar proton pumping ATPase-dependent luminal acidification in the epididymis. Asian J Androl. 2007;9(4):476-82 - PMID: 17589784 - DOI: 10.1111/j.1745-7262.2007.00299.x
Da Silva N, Smith TB Exploring the role of mononuclear phagocytes in the epididymis. Asian J Androl. 2015;17(4):591-6 - PMID: 25966624 - PMCID: PMC4492049 - DOI: 10.4103/1008-682X.153540
Breton S, Ruan YC, Park YJ, Kim B Regulation of epithelial function, differentiation, and remodeling in the epididymis. Asian J Androl. 2015;18(1):3-9 - PMID: 26585699 - PMCID: PMC4736353 - DOI: 10.4103/1008-682X.165946
Zhu B, Jaffer F, Nztiachristos V, Weissleder R Development of a near infrared fluorescence catheter: operating characteristics and feasibility for atherosclerotic plaque detection J Phys D Appl Phys. 2005;38:2701-2707
Bogdanov A, Petherick P, Marecos E, Weissleder R In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation. Nucl Med Biol. 1997;24(8):739-42 - PMID: 9428599 - DOI: 10.1016/s0969-8051(97)00117-0
Ntziachristos V, Bremer C, Weissleder R Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging Eur J Radiol. 2002;13:195-208 - PMID: 12541130 - DOI: 10.1007/s00330-002-1524-x
Bremer C, Ntziachristos V, Weissleder R Optical-based molecular imaging: contrast agents and potential medical applications Eur J Radiol. 2002;13:231-43 - PMID: 12598985 - DOI: 10.1007/s00330-002-1610-0
Wunderbaldinger P, Bogdanov A, Weissleder R New approaches for imaging in gene therapy Eur J Radiol. 2000;34:156-65 - PMID: 10927158 - DOI: 10.1016/s0720-048x(00)00196-0
Saksena MA, Saokar A, Harisinghani MG Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging. Eur J Radiol. 2006;58(3):367-74 - PMID: 16472955 - DOI: 10.1016/j.ejrad.2005.12.041
Boland GW, Guimaraes AS, Mueller PR Radiology report turnaround: expectations and solutions. Eur J Radiol. 2008;18(7):1326-8 - PMID: 18327594 - DOI: 10.1007/s00330-008-0905-1
Boland GW, Guimaraes AS, Mueller PR The radiologist's conundrum: benefits and costs of increasing CT capacity and utilization. Eur J Radiol. 2008;19(1):9-11; discussion 12 - PMID: 18766347 - DOI: 10.1007/s00330-008-1159-7
Boland GW, Guimaraes AS, Mueller PR The evolving radiology landscape: the importance of effective leadership. Eur J Radiol. 2009;19(10):2321-5 - PMID: 19471944 - DOI: 10.1007/s00330-009-1427-1
Weissleder R, Reimer P Iron oxide based magnetopharmaceuticals for MR imaging Eur J Radiol. 1993;3:198-212
Rajendran R*, Ronald JA*, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections. Microsc Micoranal. 2009;15:338-44 - PMID: 19575834 - PMCID: PMC2802450 - DOI: 10.1017/S1431927609090813
Li Y, Zhao T, Liu B, Halaweish I, Mazitschek R, Duan X, Alam HB Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model. J Trauma Acute Care Surg. 2015;78(2):378-85 - PMID: 25757125 - PMCID: PMC4357277 - DOI: 10.1097/TA.0000000000000510
Berteloot A, Malo C, Breton S, Brunette M Fast sampling, rapid filtration apparatus: principal characteristics and validation from studies of D-glucose transport in human jejunal brush-border membrane vesicles. J Membr Biol. 1991;122(2):111-25 - PMID: 1895337 - DOI: 10.1007/BF01872635
Laprade R, Lapointe JY, Breton S, Duplain M, Cardinal J Intracellular potassium activity in mammalian proximal tubule: effect of perturbations in transepithelial sodium transport. J Membr Biol. 1991;121(3):249-59 - PMID: 1865489 - DOI: 10.1007/BF01951558
Macri P, Breton S, Marsolais M, Lapointe J, Laprade R Hypertonicity decreases basolateral K+ and Cl- conductances in rabbit proximal convoluted tubule. J Membr Biol. 1997;155(3):229-37 - PMID: 9050446 - DOI: 10.1007/s002329900175
Wollack JW, Monson BJ, Dozier JK, Dalluge JJ, Poss K, Hilderbrand SA, Distefano MD Site-Specific Labeling of Proteins and Peptides with Trans-cyclooctene Containing Handles Capable of Tetrazine Ligation. Chem Biol Drug Des. 2014;84(2):140-7 - PMID: 24899362 - PMCID: PMC4107141 - DOI: 10.1111/cbdd.12303
Kevin Li-Chun H, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis. J Neuroimmunol. 2015;287:36-42 - PMID: 26439960 - PMCID: PMC4595933 - DOI: 10.1016/j.jneuroim.2015.08.006
Brinkmann R, Koop N, Ozdemir M, Alt C, Sch Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam. Laser Surg Med. 2003;32:252-64 - PMID: 12696092 - DOI: 10.1002/lsm.10150
Lin C, Weaver Y, Birngruber R, Fujimoto J, Puliafito CP Intraocular microsurgery with a picosecond Nd:YAG laser. Laser Surg Med. 1995;15:44-53 - PMID: 7997047 - DOI: 10.1002/lsm.1900150107
Brinkmann R, H Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen. Laser Surg Med. 2000;27(5):451-64 - PMID: 11126439 - DOI: 10.1002/1096-9101(2000)27:5<451::AID-LSM1006>3.0.CO;2-1
Islam T, Harisinghani MG Prostate cancer imaging: what the next decade holds. Expert Rev Med Devices. 2010;7(5):577-9 - PMID: 20822379 - DOI: 10.1586/erd.10.43
Harisinghani MG, Saksena M, Ross RW, Tabatabaei S, Dahl D, McDougal S, Weissleder R A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation. Urology. 2005;66(5):1066-71 - PMID: 16286125 - DOI: 10.1016/j.urology.2005.05.049
Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG Pilot Study Evaluating Use of Lymphotrophic Nanoparticle-Enhanced Magnetic Resonance Imaging for Assessing Lymph Nodes in Renal Cell Cancer. Urology. 2008;71(4):708-12 - PMID: 18295316 - DOI: 10.1016/j.urology.2007.11.096
Pittet M, Speiser D, Valmori D, Rimoldi D, Lienard D, Lejeune F, Cerottini J, Romero P Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients. Int Immunopharmacol. 2001;1:1235-47 - PMID: 11460305 - DOI: 10.1016/s1567-5769(01)00048-0
Simonova M, Weissleder R, Sergeyev N, Vilissova N, Bogdanov A Jr Targeting of green fluorescent protein expression to the cell surface Biochem Bioph Res Co. 1999;262:638-42 - PMID: 10471377 - DOI: 10.1006/bbrc.1999.1251
Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH A novel in vivo regulatory role of P-glycoprotein in alloimmunity. Biochem Bioph Res Co. 2010;394(3):646-52 - PMID: 20230790 - PMCID: PMC3756468 - DOI: 10.1016/j.bbrc.2010.03.040
Choi HK, Yessayan D, Choi HJ, Schellenberger E, Bogdanov A, Josephson L, Weissleder R, Ntziachristos V. Quantitative analysis of chemotherapeutic effects in tumors using in vivo staining and correlative histology Cell Oncol. 2005;27(3):183-90 - PMID: 16037639 - PMCID: PMC4615174 - DOI: 10.1155/2005/791936
Schoepf U, Marecos EM, Melder RJ, Jain RK, Weissleder R Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. Biotechniques. 1998;24(4):642-6, 648-51 - PMID: 9564539 - DOI: 10.2144/98244rr01
Hilderbrand SA, Weissleder R One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes. Tetrahedron Lett. 2007;48(25):4383-4385 - PMID: 19834587 - PMCID: PMC2761723 - DOI: 10.1016/j.tetlet.2007.04.088
Pham W, Weissleder R, Tung CH A practical approach for the preparation of monofunctional azulenyl squaraine dye. Tetrahedron Lett. 2003;44(20):3975-3978 - PMID: 20740053 - PMCID: PMC2926986 - DOI: 10.1016/S0040-4039(03)00819-0
Pham W, Weissleder R, Tung CH Intermolecular [8+2] cycloaddition reactions of 2H-3-methoxycarbonylcyclohepta[b]furan-2-one with vinyl ethers: an approach to bicyclo[5.3.0]azulene derivatives. Tetrahedron Lett. 2002;43(1):19-20 - PMID: 20740048 - PMCID: PMC2926969 - DOI: 10.1016/S0040-4039(01)02061-5
Shao H, Yoon TJ, Liong M, Weissleder R, Lee H Magnetic nanoparticles for biomedical NMR-based diagnostics Beilstein J Nanotechnol. 2010;1:142154 - PMID: 21977404 - PMCID: PMC3045933 - DOI: 10.3762/bjnano.1.17
Panchenko MP, Silva N, Stone JR Up-regulation of a hydrogen peroxide-responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasia. Cardiovasc Pathol. 2008;18(3):167-72 - PMID: 18508286 - PMCID: PMC2723736 - DOI: 10.1016/j.carpath.2008.03.008
Rabkin E, Schoen F Cardiovascular tissue engineering. Cardiovasc Pathol. 2002;11:305-17 - PMID: 12459430 - DOI: 10.1016/s1054-8807(02)00130-8
Mendelson K, Aikawa E, Mettler B, Sales V, Martin D, Mayer J, Schoen F Healing and remodeling of bioengineered pulmonary artery patches implanted in sheep. Cardiovasc Pathol. 2007;16:277-82 - PMID: 17868878 - DOI: 10.1016/j.carpath.2007.03.008
Collins AB, Smith RN, Stone JR Classification of amyloid deposits in diagnostic cardiac specimens by immunofluorescence. Cardiovasc Pathol. 2008;18(4):205-16 - PMID: 18619857 - DOI: 10.1016/j.carpath.2008.05.004
Stone JR, Basso C, Baandrup UT, Bruneval P, Butany J, Gallagher PJ, Halushka MK, Miller DV, Padera RF, Radio SJ, Sheppard MN, Suvarna K, Tan CD, Thiene G, van der Wal AC, Veinot JP Recommendations for processing cardiovascular surgical pathology specimens: a consensus statement from the Standards and Definitions Committee of the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology. Cardiovasc Pathol. 2011;21(1):2-16 - PMID: 21353600 - DOI: 10.1016/j.carpath.2011.01.001
Leone O, Veinot JP, Angelini A, Baandrup UT, Basso C, Berry G, Bruneval P, Burke M, Butany J, Calabrese F, d'Amati G, Edwards WD, Fallon JT, Fishbein MC, Gallagher PJ, Halushka MK, McManus B, Pucci A, Rodriguez ER, Saffitz JE, Sheppard MN, Steenbergen C, Stone JR, Tan C, Thiene G, van der Wal AC, Winters GL 2011 Consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. Cardiovasc Pathol. 2011;21(4):245-74 - PMID: 22137237 - DOI: 10.1016/j.carpath.2011.10.001
Siddiquee Z, Zane NA, Smith RN, Stone JR Dense IgG4 plasma cell infiltrates associated with chronic infectious aortitis: implications for the diagnosis of IgG4-related disease. Cardiovasc Pathol. 2012;21(6):470-5 - PMID: 22406174 - DOI: 10.1016/j.carpath.2012.02.001
Wang H, Albadawi H, Siddiquee Z, Stone JM, Panchenko MP, Watkins MT, Stone JR Altered vascular activation due to deficiency of the NADPH oxidase component p22(phox.) Cardiovasc Pathol. 2013;23(1):35-42 - PMID: 24035466 - DOI: 10.1016/j.carpath.2013.08.003
Stone JR Novel prognostic tissue markers in congestive heart failure. Cardiovasc Pathol. 2014;24(2):65-70 - PMID: 25453729 - DOI: 10.1016/j.carpath.2014.07.010
Stone JR, Bruneval P, Angelini A, Bartoloni G, Basso C, Batoroeva L, Buja LM, Butany J, d'Amati G, Fallon JT, Gittenberger-de Groot AC, Gouveia RH, Halushka MK, Kelly KL, Kholova I, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Suvarna SK, Tan CD, Thiene G, van der Wal AC, Veinot JP Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. Cardiovasc Pathol. 2015;24(5):267-278 - PMID: 26051917 - DOI: 10.1016/j.carpath.2015.05.001
Huck A, Pozdnyakova O, Brunner A, Higgins JM, Fathi AT, Hasserjian RP Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia. Leuk Res. 2015;39(10):1034-40 - PMID: 26220865 - PMCID: PMC5764101 - DOI: 10.1016/j.leukres.2015.06.012
Wei CL, Valvano JW, Feldman MD, Nahrendorf M, Peshock R, Pearce JA Volume catheter parallel conductance varies between end-systole and end-diastole. IEEE T Biomed Eng. 2007;54(8):1480-9 - PMID: 17694869 - DOI: 10.1109/TBME.2007.890732
Framme C, Walter A, Berger L, Prahs P, Alt C, Theisen-Kunde D, Kowal J, Brinkmann R Selective Retina Therapy in Acute and Chronic-Recurrent Central Serous Chorioretinopathy. Ophthalmologica. 2015;234(4):177-188 - PMID: 26368551 - DOI: 10.1159/000439188
Kim Y, Choi Y, Weissleder R, Tung CH Membrane permeable esterase-activated fluorescent imaging probe. Bioorg Med Chem Lett. 2007;17(18):5054-7 - PMID: 17664067 - PMCID: PMC1995663 - DOI: 10.1016/j.bmcl.2007.07.026
Mazitschek R, Patel V, Wirth D, Clardy J Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. Bioorg Med Chem Lett. 2008;18(9):2809-12 - PMID: 18430569 - PMCID: PMC2408937 - DOI: 10.1016/j.bmcl.2008.04.007
Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L A stabilized demethoxyviridin derivative inhibits PI3 kinase. Bioorg Med Chem Lett. 2009;19(15):4223-7 - PMID: 19523825 - PMCID: PMC2877487 - DOI: 10.1016/j.bmcl.2009.05.105
Martyn DC, Cortese JF, Tyndall E, Dick J, Mazitschek R, Munoz B, Clardy J Antiplasmodial activity of piperazine sulfonamides. Bioorg Med Chem Lett. 2009;20(1):218-21 - PMID: 19914069 - DOI: 10.1016/j.bmcl.2009.10.130
Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines. Bioorg Med Chem Lett. 2009;20(1):228-31 - PMID: 19914064 - DOI: 10.1016/j.bmcl.2009.10.133
Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Hsieh YT, Kim YM, Lomenick B, Okemoto K, Landaw EM, Wang D, Mazitschek R, Bradner JE, Sakamoto KM Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells. Leuk Lymphoma. 2011;52(8):1544-55 - PMID: 21699378 - PMCID: PMC4113006 - DOI: 10.3109/10428194.2011.570821
Haase A, Rigosi E, Frasnelli E, Trona F, Tessarolo F, Vinegoni C, Anfora G, Vallortigara G, Antolini R A multimodal approach for tracing lateralisation along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies. Eur Biophys J. 2011;40(11):1247-1258 - PMID: 21956452 - PMCID: PMC3366498 - DOI: 10.1007/s00249-011-0748-6
Bolondi G, Garuti C, Corradini E, Zoller H, Vogel W, Finkenstedt A, Babitt JL, Lin HY, Pietrangelo A Altered hepatic BMP signaling pathway in human HFE hemochromatosis. Blood Cells Mol Dis. 2010;45(4):308-12 - PMID: 20863724 - PMCID: PMC3295241 - DOI: 10.1016/j.bcmd.2010.08.010
Breton S, Lisanti MP, Tyszkowski R, McLaughlin M, Brown D Basolateral distribution of caveolin-1 in the kidney. Absence from H+-atpase-coated endocytic vesicles in intercalated cells. J Histochem Cytochem. 1998;46(2):205-14 - PMID: 9446827 - DOI: 10.1177/002215549804600209
Swirski F, D'Sa A, Kianpour S, Inman M, Stampfli M Prolonged ovalbumin exposure attenuates airway hyperresponsiveness and T cell function in mice. Int Arch Allergy Imm. 2006;141(2):130-40 - PMID: 16864992 - DOI: 10.1159/000094715
Ripoll J, Ntziachristos V. Quantitative point source photoacoustic inversion formulas for scattering and absorbing media Hys Rev E Stat Nonlin Soft Matter Phys. 2005;71(3 Pt 1):031912 - PMID: 15903464 - DOI: 10.1103/PhysRevE.71.031912
Figueiredo JL, Siegel C, Nahrendorf M, Weissleder R Intraoperative Near-Infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury. World J Surg. 2010;34 (2):336-343 - PMID: 20033407 - PMCID: PMC2809822 - DOI: 10.1007/s00268-009-0332-8
Figueiredo JL, Nahrendorf M, Vinegoni C, Weissleder R Intraoperative Near-infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury: Reply. World J Surg. 2011;35(3):694-5 - PMID: 20645091 - DOI: 10.1007/s00268-010-0728-5
Teixeira GV, Chikota H, Teixeira T, Manfro G, Pai SI, Tufano RP Incidence of malignancy in thyroid nodules determined to be follicular lesions of undetermined significance on fine-needle aspiration. World J Surg. 2012;36(1):69-74 - PMID: 22057754 - DOI: 10.1007/s00268-011-1336-8
Dodd CH, Hsu HC, Chu WJ, Yang P, Zhang HG, Mountz JD Jr, Zinn K, Forder J, Josephson L, Weissleder R, Mountz JM, Mountz JD Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles J Immunol Methods. 2001;256:89-105 - PMID: 11516758 - DOI: 10.1016/s0022-1759(01)00433-1
Kuzmin A, Purans J, Cazzanelli E, Vinegoni C, Mariotto G XRD, EXAFS and Raman spectroscopy studies of pure ground WO3 and mixed W1-xRexO3-y polycrystals J Appl Phys. 1998;84:5515-24
Keliher EJ, Reiner T, Thurber GM, Upadhyay R, Weissleder R Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells. ChemistryOpen. 2012;1(4):177-183 - PMID: 23997998 - PMCID: PMC3758109 - DOI: 10.1002/open.201200014
Zeglis BM, Emmetiere F, Pillarsetty N, Weissleder R, Lewis JS, Reiner T Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis. ChemistryOpen. 2014;3(2):48-53 - PMID: 24808990 - PMCID: PMC4000166 - DOI: 10.1002/open.201402000
Simonova M, Shtanko O, Sergeyev N, Weissleder R, Bogdanov A Jr Engineering of technetium-99m-binding artificial receptors for imaging gene expression J Gene Med. 2003;5:1056-66 - PMID: 14661181 - DOI: 10.1002/jgm.448
Baron JM, Higgins JM, Dzik WH A Revised Timeline for the Origin of Plasmodium falciparum as a Human Pathogen. J Mol Evol. 2011;73(5-6):297-304 - PMID: 22183792 - DOI: 10.1007/s00239-011-9476-x
Giorgis F, Pirri CF, Vinegoni C, Pavesi L Radiative emission properties of a-SiN:H based alloys, nanometric multilayers and light emitting devices J Lumin. 1998;80:423-427
Iyer VR, Hahn PF, Blaszkowsky LS, Thayer SP, Halpern EF, Harisinghani MG Added Value of Selected Images Embedded Into Radiology Reports to Referring Clinicians. J Am Coll Radiol. 2010;7(3):205-210 - PMID: 20193926 - PMCID: PMC3086392 - DOI: 10.1016/j.jacr.2009.10.014
Mitchell DG, Javitt MC, Glanc P, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Horowitz NS, Pandharipande PV, Pannu HK, Podrasky AE, Royal HD, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM ACR Appropriateness Criteria Staging and Follow-up of Ovarian Cancer. J Am Coll Radiol. 2013;10(11):822-7 - PMID: 24183551 - DOI: 10.1016/j.jacr.2013.07.017
Ross R, Harisinghani M New clinical imaging modalities in prostate cancer. Hematol Oncol Clin N. 2006;20(4):811-30 - PMID: 16861116 - DOI: 10.1016/j.hoc.2006.03.009
Eisner BH, Kurtz MP, Harisinghani MG Evolving Role of Magnetic Resonance Imaging in Renal Cancer Imaging. J Endourol. 2010;24(5):707-11 - PMID: 20433369 - DOI: 10.1089/end.2009.0507
de la Rosette J, Ahmed H, Barentsz J, Johansen TB, Brausi M, Emberton M, Frauscher F, Greene D, Harisinghani M, Haustermans K, Heidenreich A, Kovacs G, Mason M, Montironi R, Mouraviev V, de Reijke T, Taneja S, Thuroff S, Tombal B, Trachtenberg J, Wijkstra H, Polascik T Focal therapy in prostate cancer-report from a consensus panel. J Endourol. 2010;24(5):775-80 - PMID: 20477543 - DOI: 10.1089/end.2009.0596
Petersein J, Saini S, Weissleder R Liver. II: Iron oxide-based reticuloendothelial contrast agents for MR imaging. Clinical review. Magn Reson Imaging. 1996;4(1):53-60 - PMID: 8673716
Gupta H, Weissleder R Targeted contrast agents in MR imaging. Magn Reson Imaging. 1996;4(1):171-84 - PMID: 8673713
Bader A, Reimer P, Knop E, Boker K, Christians U, Weissleder R, Sewing KF An organotypical in vitro model of the liver parenchyma for uptake studies of diagnostic MR receptor agents. Magn Reson Imaging. 1996;13(7):991-1002 - PMID: 8583878 - DOI: 10.1016/0730-725x(95)00053-j
Schaffer BK, Linker C, Papisov M, Tsai E, Nossiff N, Shibata T, Bogdanov A, Brady TJ, Weissleder R MION-ASF: biokinetics of an MR receptor agent. Magn Reson Imaging. 1993;11(3):411-7 - PMID: 7685055 - DOI: 10.1016/0730-725x(93)90074-n
Chen MC, Tsang YM, Stark DD, Weissleder R, Saini S, Brandhorst J, White DL, Engelstad BL, Ferrucci JT Hepatic metastases: rat models for imaging research. Magn Reson Imaging. 1989;7(1):1-8 - PMID: 2918813 - DOI: 10.1016/0730-725x(89)90318-4
Weissleder R, Stark DD, Elizondo G, Hahn PF, Compton C, Saini S, Wittenberg J, Ferrucci JT MRI of hepatic lymphoma. Magn Reson Imaging. 1989;6(6):675-81 - PMID: 3062298 - DOI: 10.1016/0730-725x(88)90092-6
Weissleder R, Stark DD, Compton CC, Simeone JF, Ferrucci JT Cholecystitis: diagnosis by MR imaging. Magn Reson Imaging. 1988;6(3):345-8 - PMID: 3398743 - DOI: 10.1016/0730-725x(88)90412-2
Cazzanelli E, Vinegoni C, Mariotto G, Kuzmin A, Purans J Raman and XRD spectroscopic investigations of polymorphism in tungsten trioxide powders Solid State Ionics. 1999;123:67-74
Cazzanelli E, Vinegoni C, Mariotto G, Kuzmin A, Purans J Comparative Raman study of the monoclinic-to-tetragonal phase transition in tungsten trioxide WO3 at high temperature and upon hydrogen insertion J Solid State Chem. 1999;143:24-32
Petersson M, Vinegoni C, Sunnerud H, Karlsson M Statistics of PMD in recirculating loops. IEEE Photonic Tech L. 2003;15:1543-5
Vinegoni C, Chen H, Leblanc M, Schinn G, Wegmulller M, Gisin N Distributed measurements of chromatic dispersion and nonlinear coefficient in low PMD dispersion shifted fibers IEEE Photonic Tech L. 2003;15:739-40
Wegmuller M, Demma S, Vinegoni C, Gisin N Emulator of first- and second-order polarization mode dispersion. IEEE Photonic Tech L. 2002;14:630-2
Vinegoni C, Wegmuller M, Gisin N Measurements of the nonlinear coefficient of standard SMF,DSF, and DSC fibers using a self-aligned interferometer and a Faraday mirror IEEE Photonic Tech L. 2001;13:1337-9
Wegmuller M, Legre M, Oberson P, Guinnard O, Guinnard L, Vinegoni C, Gisin N Analysis of the polarization evolution in a ribbon cable using high resolution OFDR IEEE Photonic Tech L. 2000;13:145-7
Pauk M, Grgurevic L, Brkljacic J, Kufner V, Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt JL, Lin HY, Volarevic S, Vukicevic S Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice. Int Orthop. 2014;39(1):161-172 - PMID: 25300398 - DOI: 10.1007/s00264-014-2550-4
Ueno T, Ikeda T, Ikeda K, Taniuchi H, Suda S, Yeung MY, Matsuno N HMGB-1 as a Useful Prognostic Biomarker in Sepsis-Induced Organ Failure in Patients Undergoing PMX-DHP. J Surg Res. 2009;171(1):183-90 - PMID: 20338589 - DOI: 10.1016/j.jss.2009.11.708
Zhao T, Li Y, Liu B, Halaweish I, Mazitschek R, Alam HB Selective inhibition of histone deacetylase 6 alters the composition of circulating blood cells in a lethal septic model. J Surg Res. 2014;190(2):647-54 - PMID: 24613069 - PMCID: PMC4267528 - DOI: 10.1016/j.jss.2014.01.056
Zhao Y, Zhou P, Liu B, Bambakidis T, Mazitschek R, Alam HB, Li Y Protective effect of suberoylanilide hydroxamic acid against lipopolysaccharide-induced liver damage in rodents. J Surg Res. 2014;194(2):544-550 - PMID: 25479907 - PMCID: PMC4361238 - DOI: 10.1016/j.jss.2014.10.056
McDermott S, Hedgire SS, Hahn PF, Mueller PR, Harisinghani MG Image-Guided Biopsy of Suspicious Lymph Nodes in Patients with Known Primary Malignancies. J Vasc Interv Radiol. 2012;23(3):371-6 - PMID: 22265244 - DOI: 10.1016/j.jvir.2011.11.028
Erdem SS, Sazonova IY, Hara T, Jaffer FA, McCarthy JR Detection and treatment of intravascular thrombi with magnetofluorescent nanoparticles. Method Enzymol. 2012;508:191-209 - PMID: 22449927 - DOI: 10.1016/B978-0-12-391860-4.00010-0
Oklu R, Stone JR, Albadawi H, Watkins MT Extracellular Traps in Lipid-Rich Lesions of Carotid Atherosclerotic Plaques: Implications for Lipoprotein Retention and Lesion Progression. J Vasc Interv Radiol. 2014;25(4):631-4 - PMID: 24581730 - DOI: 10.1016/j.jvir.2013.12.567
Lo Gullo R, Mishra S, Lira DA, Padole A, Otrakji A, Khawaja RD, Pourjabbar S, Singh S, Shepard JO, Digumarthy SR, Kalra MK, Stone JR Quantification of interstitial fluid on whole body CT: comparison with whole body autopsy. Forensic Sci Med Pathol. 2015;11(4):488-496 - PMID: 26541472 - DOI: 10.1007/s12024-015-9728-y
Xia Z, Huang X, Zhou X, Sun Y, Ntziachristos V, Wong S. Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation IEEE T Inf Technol B. 0;12:569-578
Ueno T, Omura T, Takahashi T, Matsumoto H, Takahashi Y, Kakita A, Yamashina S Liver transplantation using liver grafts preserved under high pressure. Artif Organs. 2005;29(10):849-55 - PMID: 16185349 - DOI: 10.1111/j.1525-1594.2005.00139.x
Bruckner C, McCarthy JR, Daniell HW, A spectroscopic and computational study of the singlet and triplet excited states of synthetic beta-functionalized chlorins Chem Phys. 2003;294:285-303
Ross R, Harisinghani M Prostate cancer imaging-what the urologic oncologist needs to know. Radiol Clin North Am. 2006;44(5):711-22 - PMID: 17030222 - DOI: 10.1016/j.rcl.2006.07.002
Hedgire SS, Pargaonkar VK, Elmi A, Harisinghani AM, Harisinghani MG Pelvic nodal imaging. Radiol Clin North Am. 2012;50(6):1111-25 - PMID: 23122041 - DOI: 10.1016/j.rcl.2012.08.002
Kim YR, Savellano MD, Weissleder R, Bogdanov A Jr Steady-state and dynamic contrast MR imaging of human prostate cancer xenograft tumors: a comparative study Technol Cancer Res T. 2002;1:489-95 - PMID: 12625776 - DOI: 10.1177/153303460200100609
Vinegoni C, Cazzanelli M, Trivelli A, Lunney GJ, Mariotto G, Levy J Morphological and optical characterization of GaN prepared by pulsed laser ablation Surf Coat Tech. 2000;124:272-7
Bogdanov AA Jr, Simonova M, Weissleder R Engineering membrane proteins for nuclear medicine: applications for gene therapy and cell tracking Q J Nucl Med Mol IM. 2000;44:224-35 - PMID: 11105587
Wunderbaldinger P, Josephson L, Weissleder R Crosslinked iron oxides (CLIO): a new platform for the development of targeted MR contrast agents Acad Radiol. 2002;9 Suppl 2:S304-6 - PMID: 12188255 - DOI: 10.1016/s1076-6332(03)80210-6
Schellenberger EA, Hogemann D, Josephson L, Weissleder R Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Acad Radiol. 2002;9 Suppl 2:S310-1 - PMID: 12188257 - DOI: 10.1016/s1076-6332(03)80212-x
Ntziachristos, V, Bremer C, Tung C, Weissleder R Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT) Acad Radiol. 2002;9 Suppl 2:S323-5 - PMID: 12188262 - DOI: 10.1016/s1076-6332(03)80217-9
Mahmood U, Weissleder R Some tools for molecular imaging Acad Radiol. 2002;9:629-31 - PMID: 12061735 - DOI: 10.1016/s1076-6332(03)80306-9
Harisinghani MG, Barentsz JO, Hahn PF, Deserno W, de la Rosette J, Saini S, Marten K, Weissleder R MR lymphangiography for detection of minimal nodal disease in patients with prostate cancer Acad Radiol. 2002;9 Suppl 2:S312-3 - PMID: 12188258 - DOI: 10.1016/s1076-6332(03)80213-1
Bremer C, Tung CH, Weissleder R Molecular imaging of MMP expression and therapeutic MMP inhibition Acad Radiol. 2002;9 Suppl 2:S314-5 - PMID: 12188259 - DOI: 10.1016/s1076-6332(03)80214-3
Wagenaar DJ, Weissleder R, Hengerer A Glossary of molecular imaging terminology Acad Radiol. 2001;8:409-20 - PMID: 11345272 - DOI: 10.1016/S1076-6332(03)80549-4
Bremer C, Weissleder R In vivo imaging of gene expression Acad Radiol. 2001;8:15-23 - PMID: 11201452 - DOI: 10.1016/s1076-6332(03)80739-0
Harisinghani MG, Saini S, Hahn PF, Weissleder R, Mueller PR MR imaging of lymph nodes in patients with primary abdominal and pelvic malignancies using ultrasmall superparamagnetic iron oxide (Combidex). Acad Radiol. 1998;5 Suppl 1:S167-9, discussion S183-4 - PMID: 9561072 - DOI: 10.1016/s1076-6332(98)80095-0
Hartman RI, Chang CY, Wo JY, Eisenberg JD, Hong TS, Harisinghani MG, Gazelle GS, Pandharipande PV Optimizing Adjuvant Treatment Decisions for Stage T2 Rectal Cancer Based on Mesorectal Node Size: A Decision Analysis. Acad Radiol. 2012;20(1):79-89 - PMID: 22947271 - PMCID: PMC3525763 - DOI: 10.1016/j.acra.2012.07.010
Saokar A, Braschi M, Harisinghani M Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging. Abdom Imaging. 2006;31(6):660-7 - PMID: 16680506 - DOI: 10.1007/s00261-006-9006-2
Bouley R, Hawthorn G, Russo L, Lin HY, Ausiello D, Brown D Aquaporin 2 (AQP2) and vasopressin receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in "endocytosis-resistant" membrane domains after vasopressin treatment. Abdom Imaging. 2005;:ePub - PMID: 16104839
Roedl JB, Blake MA, Holalkere NS, Mueller PR, Colen RR, Harisinghani MG Lymph node staging in esophageal adenocarcinoma with PET-CT based on a visual analysis and based on metabolic parameters. Abdom Imaging. 2008;34(5):610-7 - PMID: 18830663 - DOI: 10.1007/s00261-008-9447-x
Quencer KB, Nimkin K, Mino-Kenudson M, Gee MS Detecting active inflammation and fibrosis in pediatric Crohn's disease: prospective evaluation of MR-E and CT-E. Abdom Imaging. 2013;38(4):705-13 - PMID: 23361877 - PMCID: PMC4390174 - DOI: 10.1007/s00261-013-9981-z
Hedgire SS, Eberhardt SC, Borczuk R, McDermott S, Harisinghani MG Interpretation and reporting multiparametric prostate MRI: a primer for residents and novices. Abdom Imaging. 2014;39(5):1036-51 - PMID: 24566965 - DOI: 10.1007/s00261-014-0097-x
Iyer VR, Hedgire SS, Hoskote SS, Borczuk D, Harisinghani MG Retrospective cohort study of portacaval lymphadenopathy identified on multidetector CT and implications for follow-up. Abdom Imaging. 2015;40(6):1481-6 - PMID: 25516214 - DOI: 10.1007/s00261-014-0328-1
Lee DK, Nahrendorf M, Schellingerhout D, Kim DE Will molecular optical imaging have clinically important roles in stroke management, and how? J Clin Neurol. 2010;6(1):10-8 - PMID: 20386638 - PMCID: PMC2851295 - DOI: 10.3988/jcn.2010.6.1.10
Weber GF, Swirski FK Immunopathogenesis of abdominal sepsis. Langenbecks Arch Surg. 2014;399(1):1-9 - PMID: 24121723 - DOI: 10.1007/s00423-013-1129-7
Cazzanelli M, Vinegoni C, Lunney JG, O'Donnel KP, Middleton PG, Trager-Cowan C, Pavesi L Luminescence properties of GaN thin films prepared by pulsed laser deposition Mat Sci Eng B-Solid. 1999;59:137-140
Harisinghani MG, Jhaveri KS, Weissleder R, Schima W, Saini S, Hahn PF, Mueller PR MRI contrast agents for evaluating focal hepatic lesions Clin Radiol. 2001;56:714-25 - PMID: 11585393 - DOI: 10.1053/crad.2001.0764
Johnson J, Swirski F, Gajewska B, Wiley R, Fattouh R, Pacitto S, Wong J, Stampfli M, Jordana M Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes. Am J Physiol-Lung C. 2007;293:L730-9 - PMID: 17586699 - DOI: 10.1152/ajplung.00056.2007
Vinegoni C, Wegmuller M, Huttner B, Gisin N Measurement of nonlinear polarization rotation in high birefringence optical fibers at telecom wavelength. 2000;2;314-184 J Opt A-Pure Appl Opt . 2000;2:314-184
Grimm J, Wunder A. Current state of molecular imaging research Rofo-Fortschr Rontg. 2005;177(3):326-37 - PMID: 15719293 - DOI: 10.1055/s-2005-857946
Samir AE, Allegretti AS, Zhu Q, Dhyani M, Anvari A, Sullivan DA, Trottier CA, Dougherty S, Williams WW, Babitt JL, Wenger J, Thadhani RI, Lin HY Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys. BMC Nephrol. 2015;16(1):119 - PMID: 26227484 - PMCID: PMC4521488 - DOI: 10.1186/s12882-015-0120-7
Gao M, Lewis G, Turner GM, Soubret A, Ntziachristos V. Effects of background fluorescence in fluorescence molecular tomography Appl Optics. 2005;44(26):5468-74 - PMID: 16161661 - DOI: 10.1364/ao.44.005468
Faris GW, Ntziachristos V, Rector DM, Wang L Topics in Biomedical Optics:introduction. Appl Optics. 2007;46(10):1595-6 - PMID: 17356600
Hooper BA, Domankevitz Y, Lin CP, Anderson RR Precise, controlled laser delivery with evanescent optical waves. Appl Optics. 1999;38(25):5511-7 - PMID: 18324060 - DOI: 10.1364/ao.38.005511
Cazzanelli E, Mariotto G, Vinegoni C, Kuzmin A, Purans J Color centers and polymorphism in pure and WO3 and mixed ReO3-WO3 powders. Ionics 2000;5;335-44 Ionics. 2000;5:335-44
Winkler DA, Burden FR, Yan B, Weissleder R, Tassa C, Shaw S, Epa VC Modelling and predicting the biological effects of nanomaterials. SAR QSAR Environ Res. 2014;25(2):161-72 - PMID: 24625316 - DOI: 10.1080/1062936X.2013.874367
Graves EE, Culver JP, Ripoll J, Weissleder R, Ntziachristos V Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography J Opt Soc Am A . 2004;21(2):231-41 - PMID: 14763766 - DOI: 10.1364/josaa.21.000231
van der Laan AM, Nahrendorf M, Piek JJ Republished: Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response. Postgrad Med J. 2013;89(1047):52-8 - PMID: 23257717 - DOI: 10.1136/postgradmedj-2012-301623rep
Dip PV, Saw WG, Roessle M, Marshansky V, Grüber G Solution structure of subunit a, a (104-363), of the Saccharomyces cerevisiae V-ATPase and the importance of its C-terminus in structure formation. J Bioenerg Biomembr. 2012;44(3):341-50 - PMID: 22562380 - DOI: 10.1007/s10863-012-9442-3
Tan W, Vinegoni C, Norman J, Desai T, Boppart S Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Techniq. 2007;70(4):361-71 - PMID: 17262787 - DOI: 10.1002/jemt.20420
Harisinghani MG, Saini S, Weissleder R, Rubin D, deLange E, Harms S, Weinreb J, Small W, Sukerkar A, Brown JJ, Zelch J, Lucas M, Morris M, Hahn PF Splenic imaging with ultrasmall superparamagnetic iron oxide ferumoxtran-10 (AMI-7227): preliminary observations J Comput Assist Tomogr. 2001;25:770-6 - PMID: 11584239 - DOI: 10.1097/00004728-200109000-00017
Li CS, Harisinghani MG, Lin WC, Braschi M, Hahn PF, Mueller PR Enhancement Characteristics of Ultrasmall Superparamagnetic Iron Oxide Particle Within the Prostate Gland in Patients With Primary Prostate Cancer. J Comput Assist Tomogr. 2008;32:523-528 - PMID: 18664836 - DOI: 10.1097/RCT.0b013e318136e194
Prakash P, Kalra MK, Stone JR, Shepard JA, Digumarthy SR Imaging findings of pericardial metastasis on chest computed tomography. J Comput Assist Tomogr. 2010;34(4):554-8 - PMID: 20657224 - DOI: 10.1097/RCT.0b013e3181d77d7e
Shenoy-Bhangle A, Nimkin K, Gee MS Pediatric imaging: Current and emerging techniques. J Postgrad Med. 2010;56(2):98-102 - PMID: 20622388 - DOI: 10.4103/0022-3859.65273
Sanghvi D, Harisinghani MG Modalities in modern radiology: A synopsis. J Postgrad Med. 2010;56(2):85-7 - PMID: 20622386 - DOI: 10.4103/0022-3859.65282
Ueno T, Sugino M, Nemoto H, Shoji H, Kakita A, Watanabe M Effect over time of endotoxin adsorption therapy in sepsis. Ther Apher Dial. 2005;9(2):128-36 - PMID: 15828924 - DOI: 10.1111/j.1774-9987.2005.00230.x
Horner B, Ferguson K, Randolph M, Spencer J, Carlson A, Hirsh E, Lin CP, Butler P In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036
Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036
Vinegoni C, Wegmuller M, Huttner B, Gisin N All optical switching in a highly birefringent and a standard telecom fiber using a Faraday mirror stabilization scheme. Opt Commun. 2000;182:314-18
Lee H, Purdon AM, Westervelt RM Micromanipulation of biological systems with microelectromagnets IEEE T Magn. 0;40(4):2991 - 2993
Karaosmanoglu AD, Gee MS Sonographic findings of an adrenal leiomyosarcoma. J Ultrasound Med. 2010;29(9):1369-73 - PMID: 20733196 - DOI: 10.7863/jum.2010.29.9.1369
Weissleder R, Elizondo G, Stark DD Sonographic diagnosis of subclavian and internal jugular vein thrombosis. J Ultrasound Med. 1987;6(10):577-87 - PMID: 3316690 - DOI: 10.7863/jum.1987.6.10.577
Gee MS, Harisinghani MG, Tabatabaei S Molecular imaging in urologic surgery. Urol Clin N Am. 2009;36(2):125-32 - PMID: 19406314 - DOI: 10.1016/j.ucl.2009.02.007
González RG, Copen WA, Schaefer PW, Lev MH, Pomerantz SR, Rapalino O, Chen JW, Hunter GJ, Romero JM, Buchbinder BR, Larvie M, Hirsch JA, Gupta R The Massachusetts General Hospital acute stroke imaging algorithm: an experience and evidence based approach. J Neurointerv Surg. 2013;5 Suppl 1:i7-i12 - PMID: 23493340 - PMCID: PMC3623036 - DOI: 10.1136/neurintsurg-2013-010715
Oklu R, Deipolyi AR, Wicky S, Ergul E, Deik AA, Chen JW, Hirsch JA, Wojtkiewicz GR, Clish CB Identification of small compound biomarkers of pituitary adenoma: a bilateral inferior petrosal sinus sampling study. J Neurointerv Surg. 2013;6(7):541-6 - PMID: 24005126 - DOI: 10.1136/neurintsurg-2013-010821
Hilderbrand SA Labels and probes for live cell imaging: overview and selection guide. Methods Mol Biol. 2009;591:17-45 - PMID: 19957122 - DOI: 10.1007/978-1-60761-404-3_2
Shah K In Vivo Imaging of the Dynamics of Different Variants of EGFR in Glioblastomas. Methods Mol Biol. 2010;680:153-164 - PMID: 21153380 - DOI: 10.1007/978-1-60761-901-7_11
Jaffer FA Intravital Fluorescence Microscopic Molecular Imaging of Atherosclerosis. Methods Mol Biol. 2010;680:131-140 - PMID: 21153378 - PMCID: PMC3051165 - DOI: 10.1007/978-1-60761-901-7_9
Shah K Imaging Fate of Stem Cells at a Cellular Resolution in the Brains of Mice. Methods Mol Biol. 2010;680:91-101 - PMID: 21153375 - DOI: 10.1007/978-1-60761-901-7_6
Haun JB, Yoon TJ, Lee H, Weissleder R Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance. Methods Mol Biol. 2011;726:33-49 - PMID: 21424441 - DOI: 10.1007/978-1-61779-052-2_3
Wu JW, Runnels JM, Lin CP Intravital imaging of hematopoietic stem cells in the mouse skull. Methods Mol Biol. 2014;1185:247-65 - PMID: 25062634 - DOI: 10.1007/978-1-4939-1133-2_17
Brettman AD, Tan PH, Tran K, Shaw SY Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles. Methods Mol Biol. 2015;1263:15-27 - PMID: 25618333 - PMCID: PMC4357233 - DOI: 10.1007/978-1-4939-2269-7_2
Ullal AV, Weissleder R Photocleavable DNA Barcoding Antibodies for Multiplexed Protein Analysis in Single Cells. Methods Mol Biol. 2015;1346:47-54 - PMID: 26542714 - DOI: 10.1007/978-1-4939-2987-0_4
Higgins JM Red Blood Cell Population Dynamics. Clin Lab Med. 2014;35(1):43-57 - PMID: 25676371 - PMCID: PMC4717490 - DOI: 10.1016/j.cll.2014.10.002
Coutinho AC, Krishnaraj A, Pires CE, Bittencourt LK, Guimaraes AR Pelvic applications of diffusion magnetic resonance images. Magn Reson Imaging Clin N Am. 2011;19(1):133-57 - PMID: 21129639 - DOI: 10.1016/j.mric.2010.10.003
Harisinghani MG The male pelvis. Magn Reson Imaging Clin N Am. 2014;22(2):xi - PMID: 24792681 - DOI: 10.1016/j.mric.2014.02.001
Sheth RA, Bittencourt LK, Guimaraes AR Diffusion-Weighted Imaging of the Male Pelvis. Magn Reson Imaging Clin N Am. 2014;22(2):145-163 - PMID: 24792675 - DOI: 10.1016/j.mric.2014.01.003
Bell DL, Stapleton CJ, Terry AR, Stone JR, Ogilvy CS Clinical presentation and treatment considerations of a ruptured posterior spinal artery pseudoaneurysm. J Clin Neurosci. 2014;21(7):1273-6 - PMID: 24572933 - DOI: 10.1016/j.jocn.2014.01.002
Weissleder R, Stark DD Magnetic resonance imaging of liver tumors. Semin Ultrasound CT MR. 1989;10(1):63-77 - PMID: 2560665
Dejesus Allison SO, Javitt MC, Glanc P, Andreotti RF, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Mitchell DG, Pandharipande PV, Pannu HK, Podrasky AE, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM ACR Appropriateness Criteria® Multiple Gestations. Ultrasound Q. 2012;28(2):149-155 - PMID: 22634795 - DOI: 10.1097/RUQ.0b013e31824bfc06
Podrasky AE, Javitt MC, Glanc P, Dubinsky T, Harisinghani MG, Harris RD, Khati NJ, Mitchell DG, Pandharipande PV, Pannu HK, Shipp TD, Siegel CL, Simpson L, Wall DJ, Wong-You-Cheong JJ, Zelop CM ACR Appropriateness Criteria® Second and Third Trimester Bleeding. Ultrasound Q. 2013;29(4):293-301 - PMID: 24263752 - DOI: 10.1097/RUQ.0000000000000044
Malka R, Lerner B Classification of fluorescence in-situ hybridization images using belief networks Pattern Recogn Lett. 2004;25(16):1777-85
Liang JS, Lee SP, Pulli B, Chen JW, Kao SC, Tsang YM, Hsieh KL Microstructural Changes in Absence Seizure Children: A Diffusion Tensor Magnetic Resonance Imaging Study. Pediatr Neonatol. 2015;57(4):318-25 - PMID: 26750405 - DOI: 10.1016/j.pedneo.2015.10.003
Schellingerhout D, Josephson L Molecular imaging of cell-based therapies. Neuroimag Clin N Am.. 2004;14(2):331-42 - PMID: 15182822 - DOI: 10.1016/j.nic.2004.03.009
Chen J, Wasserman B Vulnerable plaque imaging. Neuroimag Clin N Am.. 2005;15:609-21, xi - PMID: 16360592 - DOI: 10.1016/j.nic.2005.08.005
Berry NC, Sosnovik DE Cardiomyocyte Death: Insights from Molecular and Microstructural Magnetic Resonance Imaging. Pediatr Cardiol. 2011;32(3):290-6 - PMID: 21298427 - PMCID: PMC3078825 - DOI: 10.1007/s00246-011-9894-y
Malka R, Rom-Kedar V Bacteria-phagocyte dynamics, axiomatic modelling and mass-action kinetics. Math Biosci Eng. 2011;8(2):475-502 - PMID: 21631141 - DOI: 10.3934/mbe.2011.8.475
Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging J Vis Exp. 2009;28:1389 - PMID: 19578329 - PMCID: PMC2794886 - DOI: 10.3791/1389
Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. J Vis Exp. 2009;(30):pii:1510 - PMID: 19696720 - PMCID: PMC2736679 - DOI: 10.3791/1510
Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications. J Vis Exp. 2013;(79):e50772 - PMID: 24084440 - PMCID: PMC3924759 - DOI: 10.3791/50772
Park D, Spencer JA, Lin CP, Scadden DT Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair. J Vis Exp. 2014;(87):ePub - PMID: 24894331 - PMCID: PMC4206246 - DOI: 10.3791/51289
Mackay DD, Huesmann GR, Wu RI, Stone JR, Pless ML Giant Cell Arteritis Causing Symmetric Bilateral Posterior Circulation Infarcts. J Clin Rheumatol. 2013;19(7):393-6 - PMID: 24048110 - DOI: 10.1097/RHU.0b013e3182a6ffc1
Petropoulos AE, Schaffer BK, Cheney ML, Enochs S, Zimmer C, Weissleder R MR imaging of neuronal transport in the guinea pig facial nerve: initial findings. Acta Otolaryngol. 1995;115(4):512-6 - PMID: 7572127 - DOI: 10.3109/00016489509139358
Rabkin E, Hoerstrup S, Aikawa M, Mayer J, Schoen F Evolution of cell phenotype and extracellular matrix in tissue-engineered heart valves during in-vitro maturation and in-vivo remodeling. J Heart Valve Dis. 2002;11:308-14; discussion 314 - PMID: 12056720
Rabkin-Aikawa E, Farber M, Aikawa M, Schoen F Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves. J Heart Valve Dis. 2004;13:841-7 - PMID: 15473488
Vinegoni C, Wegmuller M, Gisin N Determination of the nonlinear coefficient n2/Aeff using a self-aligned interferometer and a Faraday mirror. . 2000;36;886 Electronic Lett. 2000;36:886-87
Islam T, Harisinghani MG Overview of nanoparticle use in cancer imaging. Cancer Biomark. 2009;5:61-7 - PMID: 19414922 - DOI: 10.3233/CBM-2009-0578
Islam T, Josephson L Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles. Cancer Biomark. 2009;5(2):99-107 - PMID: 19414927 - DOI: 10.3233/CBM-2009-0615
Harisinghani MG Nanoparticle enhanced imaging. Cancer Biomark. 2009;5(2):59 - PMID: 19414921 - DOI: 10.3233/CBM-2009-0614
Islam T, Wolf G The pharmacokinetics of the lymphotropic nanoparticle MRI contrast agent ferumoxtran-10. Cancer Biomark. 2009;5(2):69-73 - PMID: 19414923 - DOI: 10.3233/CBM-2009-0579
Sakamoto I, Takahashi T, Ueno T, Kakita A, Hayashi I, Yamashina S Regeneration of Schwann cells during extrinsic hepatic reinnervation following liver transplantation in rats. Transpl P. 2003;35(1):573-4 - PMID: 12591537 - DOI: 10.1016/s0041-1345(02)03809-5
Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T Mouse Models of Human Non-Small-Cell Lung Cancer: Raising the Bar. Cold Spring Harb Symp Quant Biol. 2005;70:241-250 - PMID: 16869760 - DOI: 10.1101/sqb.2005.70.037
Wu X, Rabkin-Aikawa E, Guleserian K, Perry T, Masuda Y, Sutherland F, Schoen F, Mayer J, Bischoff J Tissue-engineered microvessels on three-dimensional biodegradable scaffolds using human endothelial progenitor cells. Am J Phys. 2004;287:H480-7 - PMID: 15277191 - DOI: 10.1152/ajpheart.01232.2003
Libby P, Nahrendorf M, Weissleder R Molecular imaging of atherosclerosis: a progress report. Tex Heart I J. 2010;37(3):324-7 - PMID: 20548813 - PMCID: PMC2879214
Fradley MG, Thakuria JV, Collins AB, Moore SA, Stone JR Direct Tissue Evaluation via Immunofluorescence: in the Diagnosis of Hereditary Transthyretin Cardiac Amyloidosis. Tex Heart I J. 2012;39(1):71-5 - PMID: 22412233 - PMCID: PMC3298917
Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy. Clin Imaging. 2009;33(4):301-5 - PMID: 19559353 - DOI: 10.1016/j.clinimag.2009.01.013
Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. Clin Imaging. 2010;34(1):20-28 - PMID: 20122515 - DOI: 10.1016/j.clinimag.2009.03.012
Saokar A, Islam T, Jantsch M, Saksena MA, Hahn PF, Harisinghani MG Detection of lymph nodes in pelvic malignancies with computed tomography and magnetic resonance imaging. Clin Imaging. 2010;34(5):361-6 - PMID: 20813300 - DOI: 10.1016/j.clinimag.2009.07.004
Saokar A, Gee MS, Islam T, Mueller PR, Harisinghani MG Appearance of primary lymphoid malignancies on lymphotropic nanoparticle-enhanced magnetic resonance imaging using ferumoxtran-10. Clin Imaging. 2010;34(6):448-52 - PMID: 21092874 - DOI: 10.1016/j.clinimag.2009.09.008
Hedgire SS, Elmi A, Nadkarni ND, Cao K, McDermott S, Harisinghani MG Preoperative evaluation of perinephric fat invasion in patients with renal cell carcinoma: correlation with pathological findings. Clin Imaging. 2012;37(1):91-6 - PMID: 23206613 - DOI: 10.1016/j.clinimag.2012.03.005
Hedgire SS, Sainani NI, McDermott S, Hahn PF, Harisinghani MG Mono-belly and beyond: spectrum of imaging manifestations of EBV infection in the abdomen. Clin Imaging. 2013;37(4):711-7 - PMID: 23317894 - DOI: 10.1016/j.clinimag.2012.10.003
Hedgire SS, Elmi A, Kambadakone AR, Yoon S, Blake M, Harisinghani MG MDCT imaging of Alloderm biologic mesh spacers in the abdomen and pelvis - preliminary experience. Clin Imaging. 2014;38(3):279-82 - PMID: 24556330 - DOI: 10.1016/j.clinimag.2013.12.020
Hedgire SS, Tabatabaei S, McDermott S, Feldman A, Dahl DM, Harisinghani MG Diversion ahead: imaging appearance of urinary diversions and reservoirs. Clin Imaging. 2014;38(4):418-427 - PMID: 24602415 - DOI: 10.1016/j.clinimag.2014.01.017
Swirski FK Monocyte recruitment and macrophage proliferation in atherosclerosis. Kardiol Pol. 2014;72(4):311-4 - PMID: 24526549 - DOI: 10.5603/KP.a2014.0021
Zeller M, Hunter AD, McCarthy JR, Capetta SH, Bruckner C Crystal and molecular structure of [5,10,15,20-tetrakisphenyl-2-ethoxy-3-oxa-chlorinato]Ag(II). J Chem Crystallogr. 2005;35(12):935-42
Yoon TJ, Shao H, Weissleder R, Lee H Oxidation Kinetics and Magnetic Properties of Elemental Iron Nanoparticles Part. Part. Syst. Charact. 2013;30:667–671 - PMID: 24077230 - PMCID: PMC3783348 - DOI: 10.1002/ppsc.201300013
Shaw SY, Wang JC DNA knot formation in aqueous solutions J Knot Theor Ramif. 1994;3:287-294
Lerner B, Malka R Investigation of the K2 algorithm in learning Bayesian network classifiers Appl Artificial Intelligence . 2011;25(1):74-96
Wunderbaldinger P, Weissleder R [Experimental and clinical approaches to lymph node imaging] Radiologe. 2001;41:121-30 - PMID: 11253097 - DOI: 10.1007/s001170050954
Weissleder R [Experimental radiology in the USA] Radiologe. 2001;41:115 - PMID: 11253095 - DOI: 10.1007/s001170050952
Hogemann D, Basilion JP, Weissleder R [Molecular imaging in magnetic resonance tomography and nuclear medicine] Radiologe. 2001;41:116-20 - PMID: 11253096 - DOI: 10.1007/s001170050953
Bremer C, Ntziachristos V, Mahmood U, Tung CH, Weissleder R [Progress in optical imaging] Radiologe. 2001;41:131-7 - PMID: 11253098 - DOI: 10.1007/s001170050955
Bremer C, Bogdanov AA, Weissleder R [Imaging of angiogenesis] Radiologe. 2001;41:138-45 - PMID: 11253099 - DOI: 10.1007/s001170050956
Nahrendorf M, Weissleder R Advances in cardiovascular medicine through molecular imaging. Radiologe. 2007;47(1):18-24 - PMID: 17187263 - DOI: 10.1007/s00117-006-1450-z
Grimm J, Kircher MF, Weissleder R Cell tracking : Principles and applications. Radiologe. 2007;47(1):25-33 - PMID: 17187264 - DOI: 10.1007/s00117-006-1449-5
Weissleder R, Imhof H Molecular imaging -a new emphasis in radiology Radiologe. 2007;47(1):6-7 - PMID: 17136404 - DOI: 10.1007/s00117-006-1447-7
Reimer P, Weissleder R [Development and experimental use of receptor-specific MR contrast media] Radiologe. 1996;36(2):153-63 - PMID: 8867433 - DOI: 10.1007/s001170050053
Rummeny E, Weissleder R, Stark DD, Elizondo G, Ferrucci JT [Magnetic resonance tomography of focal liver and spleen lesions. Experiences using ferrite, a new RES-specific MR contrast medium] Radiologe. 1988;28(8):380-6 - PMID: 3174975
Weissleder R, Galarza D, Garza MA Lupus nephritis: Classification, clinical features and treatment Rev Invest Clin. 1987;39:263-276
Bogdanov AA Jr, Chen JW, Kang HW, Weissleder R. Magnetic resonance signal amplification probes Ernst Schering Res Found Workshop. 2005;49:147-57 - PMID: 15524215 - DOI: 10.1007/3-540-26809-x_8
Sosnovik D, Weissleder R Magnetic resonance and fluorescence based molecular imaging technologies. Prog Drug Res. 2005;62:83-115 - PMID: 16329255 - DOI: 10.1007/3-7643-7426-8_3
Tsourkas A, Weissleder R Illuminating the dynamics of intracellular activity with Mech Chem Biosyst. 2004;1:133-45 - PMID: 16783939
Mahmood U, Upadhyay R Current and Future Imaging Paradigms in Colorectal Cancer Seminars in Colon and Rectal Surgery. 2007;18(2):132-138 - PMID: 18516215 - PMCID: PMC2084349 - DOI: 10.1053/j.scrs.2007.03.007
Romero P, Pittet M, Valmori D, Speiser D, Cerundolo V, Lienard D, Lejeune F, Cerottini J Immune monitoring in cancer immunotherapy. Ernst Schering Res Found Workshop. 2000;(30):75-97 - PMID: 10943317 - DOI: 10.1007/978-3-662-04183-3_5
Sosnovik DE Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential. Top Magn Reson Imaging. 2008;19:59-68 - PMID: 18690161 - PMCID: PMC2597277 - DOI: 10.1097/RMR.0b013e318176c57b
Miyazaki T, Biology of Cholesterol Lowering in Atherosclerotic Plaques Immunol Endocrine and Metabolic Agents. 0;8(2):105-115
Shah K Imaging neural stem cell fate in mouse model of glioma. Curr Protoc Stem Cell Biol. 2009;Chapter 5:Unit5A.1 - PMID: 19306259 - DOI: 10.1002/9780470151808.sc05a01s8
Osborn EA, Jaffer FA The year in molecular imaging. J Am Coll Cardiol Img. 2009;2:97-113 - PMID: 19356541 - PMCID: PMC4802868 - DOI: 10.1016/j.jcmg.2008.11.001
Marks DL, Vinegoni C, Bredfeldt J, Boppart SA Nonlinear Interferometric Vibrational Imaging. efficient detection of Coherent Anti-Stokes Raman Scattering OPN Special Issue, Optics in 2005. 2005;16:23
Razansky D, Vinegoni C, Ntziachristos V Unprecedented in vivo views at the mesoscopic scale Biooptics World. 2009;2 (4):22-25
Sosnovik DE Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach Curr Cardiovasc Imaging Rep. 2009;2:33-39
Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, Weissleder R 18F-4V for PET-CT Imaging of VCAM-1 Expression in Atherosclerosis J Am Coll Cardiol Img. 2009;2:1213-1222 - PMID: 19833312 - PMCID: PMC2773129 - DOI: 10.1016/j.jcmg.2009.04.016
Rusanescu G, Weissleder R, Aikawa E Notch signaling in cardiovascular disease and calcification. Curr Cardiol Review. 2008;4(3):148-56 - PMID: 19936191 - PMCID: PMC2780816 - DOI: 10.2174/157340308785160552
Lu J, Liong M, Sherman S, Xia T, Kovochich M, Nel AE, Zink JI, Tamanoi F Mesoporous Silica Nanoparticles for Cancer Therapy: Energy-Dependent Cellular Uptake and Delivery of Paclitaxel to Cancer Cells. Nanobiotechnology. 2007;3(2):89-95 - PMID: 19936038 - PMCID: PMC2779038 - DOI: 10.1007/s12030-008-9003-3
Sosnovik DE, Caravan P Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents. Curr Cardiovasc Imaging Rep. 2009;2(2):87-94 - PMID: 20019886 - PMCID: PMC2794433 - DOI: 10.1007/s12410-009-0012-y
Sosnovik DE Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach. Curr Cardiovasc Imaging Rep. 2009;2(1):33-39 - PMID: 20090858 - PMCID: PMC2808047 - DOI: 10.1007/s12410-009-0005-x
Haun JB, Yoon TJ, Lee H, Weissleder R Magnetic nanoparticle biosensors. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;2(3):291-304 - PMID: 20336708 - DOI: 10.1002/wnan.84
McCarthy JR Nanomedicine and Cardiovascular Disease. Curr Cardiovasc Imaging Rep. 2010;3(1):42-49 - PMID: 20369034 - PMCID: PMC2848940 - DOI: 10.1007/s12410-009-9002-3
Huang S, Sosnovik DE Molecular and Microstructural Imaging of the Myocardium. Curr Cardiovasc Imaging Rep. 2010;3(1):26-33 - PMID: 20689659 - PMCID: PMC2916196 - DOI: 10.1007/s12410-010-9007-y
Chen HH, Josephson L, Sosnovik DE Imaging of apoptosis in the heart with nanoparticle technology. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683 - DOI: 10.1002/wnan.115
Mohr U, Weissleder R [Lymph node diagnosis with imaging methods. An overview with special reference to recent developments in the area of MR contrast media] Z Lymphol. 1996;20(1):15-20 - PMID: 8768044
Frank H, Weissleder R, Papisov M [Presentation and quantification of acute myocardial infarct using antibody-bound MR contrast medium] Z Kardiol. 1995;84(4):311-5 - PMID: 7785304
Weissleder R, Bogdanov A, Papisov M Drug targeting in magnetic resonance imaging. Magn Reson Q. 1992;8(1):55-63 - PMID: 1567758
Josephson L, Groman E, Weissleder R Contrast agents for magnetic resonance imaging of the liver. Targeted Diagn Ther. 1992;4:163-87 - PMID: 1797156
Weissleder R, Stark DD Magnetic resonance imaging of the liver. Magn Reson Q. 1989;5(2):97-121 - PMID: 2701280
Riojas GE, Weissleder R, Gonzalez HG, Miguel MC, Riojas AE, Morantes JG, Perez LET Physical principles of magnetic resonance imaging Rev Mex Radiol. 1989;43:3-12
Contag C, Weissleder R, Bachmann M, Fraser S Appllications of In Vivo Molecular Imaging in Biology and Medicine Neoreviews. 2000;1:233-240
Contag C, Fraser S, Weissleder, R Strategies in in vivo molecular imaging Neoreviews. 2000;1:225-232
Neuberger T, Greiser A, Nahrendorf M, Jakob PM, Faber C, Webb AG 23Na microscopy of the mouse heart in vivo using density-weighted chemical shift imaging. MAGMA. 2004;17(3-6):196-200 - PMID: 15580377 - DOI: 10.1007/s10334-004-0048-6
Hucker WJ, Jaffer FA F-FDG PET Imaging of Atherosclerosis-A New Approach to Detect Inflamed, High-Risk Coronary Plaques? Curr Cardiovasc Imaging Rep. 2011;4(1):1-3 - PMID: 21297872 - PMCID: PMC3032349 - DOI: 10.1007/s12410-010-9054-4
Chen HH, Josephson L, Sosnovik DE Imaging of apoptosis in the heart with nanoparticle technology. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683 - DOI: 10.1002/wnan.115
Beck JS, Marsolais M, N Dibutyryl cyclic adenosine monophosphate stimulates the sodium pump in rabbit renal cortical tubules. Ren Physiol Biochem. 1995;18(1):21-6 - PMID: 7533315 - DOI: 10.1159/000173895
Brown D, Sabolic I, Breton S Polarized expression of membrane proteins in renal epithelial cells: involvement of specialized transport vesicles and intracellular pathways. Adv Nephrol Necker Hosp. 1998;27:297-315 - PMID: 9408453
Breton S The cellular physiology of carbonic anhydrases. JOP. 2001;2(4 Suppl):159-64 - PMID: 11875253
Breton S, Smith PJS, Brown D Presence de cellules acidifiantes dans l'epididyme et le canal deferent: implication de la pompe a protons Medecine/Sciences. 1997;13:57-61
Oei T, Hedgire S, Harisinghani M Advanced cross-sectional imaging techniques for the detection and characterization of renal masses Imaging Med. 2011;3 (2):207-218
Kamberov YG, Kim J, Mazitschek R, Kuo WP, Whitman M Microarray profiling reveals the Integrated Stress Response is activated by Halofuginone in mammary epithelial cells. BMC Res Notes. 2011;4(1):381 - PMID: 21974968 - PMCID: PMC3197508 - DOI: 10.1186/1756-0500-4-381
Tekirian TL, Merriam DE, Marshansky V, Miller J, Crowley AC, Chan H, Ausiello D, Brown D, Buxbaum JD, Xia W, Wasco W Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments. Brain Res Mol Brain Res. 2001;96(1-2):14-20 - PMID: 11731004 - DOI: 10.1016/s0169-328x(01)00250-9
Thomas S, Waterman P, Chen S, Marinelli B, Seaman M, Rodig S, Ross RW, Josephson L, Weissleder R, Kelly KA Development of Secreted Protein and Acidic and Rich in Cysteine (SPARC) Targeted Nanoparticles for the Prognostic Molecular Imaging of Metastatic Prostate Cancer J Nanomedic Nanotechnol. 2011;2(4):112 - PMID: 22319675 - PMCID: PMC3273319 - DOI: 10.4172/2157-7439.1000112
Zettergren E, Vickers D, Runnels J, Lin CP, Niedre MJ Validation of a device for fluorescence sensing of rare circulating cells with diffusive light in an optical flow phantom model. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:486-9 - PMID: 22254354 - PMCID: PMC3555486 - DOI: 10.1109/IEMBS.2011.6090071
Kirkin V, Mazitschek R, Krishnan J, Steffen A, Waltenberger J, Pepper MS, Giannis A, Sleeman JP Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2. Eur J Biochem. 2001;268(21):5530-40 - PMID: 11683876 - DOI: 10.1046/j.1432-1033.2001.02476.x
Lerner B, Malka R Learning Bayesian Networks for Cytogenetic Image Classification ICPR. 2006;2:772-5
Lerner B, Malka R Belief Networks for Cytogenetic Image Classification 23rd IEEE Convention of Electrical and Electronics Engineers in Israel. 2004;6(7):297-300
Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V Bi-stability of phagocyte-bacteria interaction: when do neutrophils win the battle with Staphylococcus Aureus? 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, Italy. 2010;:ePub
Rosenthal A, Jaffer FA, Ntziachristos V Intravascular multispectral optoacoustic tomography of atherosclerosis: prospects and challenges. Imaging Med. 2012;4(3):299-310 - PMID: 23144663 - PMCID: PMC3493570 - DOI: 10.2217/iim.12.20
Yui N, Lu HJ, Bouley R, Brown D AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells. Biol Open. 2011;1(2):101-8 - PMID: 23213402 - PMCID: PMC3507199 - DOI: 10.1242/bio.2011042
Vinegoni C, Lee S, Gorbatov R, Weissleder R Motion compensation using a suctioning stabilizer for intravital microscopy Intravital. 2012;1:115-121 - PMID: 24086796 - PMCID: PMC3786172 - DOI: 10.4161/intv.23017
Alt C, Runnels J, Teo G, Lin C In vivo tracking of hematopoietic cells in the retina of chimeric mice with a scanning laser ophthalmoscope Intravital. 2012;1:132-140
Hedgire SS, Oei TN, McDermott S, Cao K, Patel M Z, Harisinghani MG Multiparametric magnetic resonance imaging of prostate cancer. Indian J Radiol Imaging. 2012;22(3):160-9 - PMID: 23599562 - PMCID: PMC3624737 - DOI: 10.4103/0971-3026.107176
Cortez-Retamozo V, Engblom C, Pittet MJ Remote control of macrophage production by cancer. OncoImmunology. 2013;2(5):e24183 - PMID: 23762799 - PMCID: PMC3667905 - DOI: 10.4161/onci.24183
Phillips JA, Mortensen LJ, Ruiz JP, Sridharan R, Kumar S, Torres M, Sharma P, Lin CP, Karp JM, Hauschka PV Advances in Single-cell Tracking of Mesenchymal Stem Cells (MSCs) During Musculoskeletal Regeneration. Orthop J Harv Med Sch. 2012;14:22-28 - PMID: 24244929 - PMCID: PMC3824625
Coffey SE, Giedt RJ, Weissleder R Automated analysis of clonal cancer cells by intravital imaging. Intravital. 2013;2(3):ePub - PMID: 24349895 - PMCID: PMC3859690 - DOI: 10.4161/intv.26138
Schietinger A, Arina A, Liu RB, Wells S, Huang J, Engels B, Bindokas V, Bartkowiak T, Lee D, Herrmann A, Piston DW, Pittet MJ, Lin PC, Zal T, Schreiber H Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer. OncoImmunology. 2013;2(11):e26677 - PMID: 24482750 - PMCID: PMC3895414 - DOI: 10.4161/onci.26677
Liu CL, Bernstein BE, Schreiber SL Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): I. CIP Treatment of Samples and Tailing Reaction with Terminal Transferase. CSH Protoc. 2008;2008:pdb.prot5002 - PMID: 21356834 - DOI: 10.1101/pdb.prot5002
Baron JM, Dighe AS, Arnaout R, Balis UJ, Black-Schaffer WS, Carter AB, Henricks WH, Higgins JM, Jackson BR, Kim J, Klepeis VE, Le LP, Louis DN, Mandelker D, Mermel CH, Michaelson JS, Nagarajan R, Platt ME, Quinn AM, Rao L, Shirts BH, Gilbertson JR The 2013 symposium on pathology data integration and clinical decision support and the current state of field. J Pathol Inform. 2014;5:2 - PMID: 24672737 - PMCID: PMC3952400 - DOI: 10.4103/2153-3539.126145
Da Silva N, Meyer-Monard S, Menot ML, Parrado A, Lebel A, Balitrand N, Fenaux P, Micléa JM, Rousselot P, Degos L, Dombret H, Chomienne C Functional G-CSF pathways in t(8;21) leukemic cells allow for differentiation induction and degradation of AML1-ETO. Hematol J. 2002;1(5):316-28 - PMID: 11920209 - DOI: 10.1038/sj.thj.6200047
Shelley CS, Da Silva N, Teodoridis JM During U937 monocytic differentiation repression of the CD43 gene promoter is mediated by the single-stranded DNA binding protein Pur alpha. Br J Haematol. 2001;115(1):159-66 - PMID: 11722429 - DOI: 10.1046/j.1365-2141.2001.03066.x
Shelley CS, Da Silva N, Georgakis A, Chomienne C, Arnaout MA Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb. Genomics. 1998;49(2):334-6 - PMID: 9598326 - DOI: 10.1006/geno.1998.5232
Da Silva N, Meyer-Monard S, Menot ML, Degos L, Baruchel A, Dombret H, Chomienne C G-CSF activates STAT pathways in Kasumi-1 myeloid leukemic cells with the t(8; 21) translocation: basis for potential therapeutic efficacy. Cytokines Cell Mol Ther. 1997;3(2):75-80 - PMID: 9287246
Ali M, Pulli B, Chen JW Molecular imaging of macrophage enzyme activity in cardiac inflammation. Curr Cardiovasc Imaging Rep. 2014;7(4):9258 - PMID: 24729833 - PMCID: PMC3979571 - DOI: 10.1007/s12410-014-9258-0
Core AB, Canali S, Babitt JL Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis. Front Pharmacol. 2014;5:104 - PMID: 24860505 - PMCID: PMC4026703 - DOI: 10.3389/fphar.2014.00104
Wang CY, Meynard D, Lin HY The role of TMPRSS6/matriptase-2 in iron regulation and anemia. Front Pharmacol. 2014;5:114 - PMID: 24966834 - PMCID: PMC4053654 - DOI: 10.3389/fphar.2014.00114
Ausiello D, Shaw S Quantitative human phenotyping: the next frontier in medicine. Trans Am Clin Climatol Assoc. 2014;125:219-28 - PMID: 25125736 - PMCID: PMC4112685
Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2014;39(10):1136-42 - PMID: 24641590 - PMCID: PMC4187206 - DOI: 10.1111/apt.12706
Mietto C, Pinciroli R, Piriyapatsom A, Thomas JG, Bry L, Delaney ML, Du Bois A, Truelove J, Ackman JB, Wojtkiewicz GR, Nahrendorf M, Kacmarek RM, Berra L Tracheal Tube Obstruction in Mechanically Ventilated Patients Assessed by High-resolution Computed Tomography. Anesthesiology. 2014;121(6):1226-1235 - PMID: 25254903 - DOI: 10.1097/ALN.0000000000000455
Swirski FK Inflammation and repair in the ischaemic myocardium. Hamostaseologie. 2014;35(1):34-6 - PMID: 25375277 - DOI: 10.5482/HAMO-14-09-0045
Arystarkhova E, Ralph DL, Liu YB, Bouley R, McDonough AA, Sweadner KJ Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2. Physiol Rep. 2014;2(12):ePub - PMID: 25472608 - PMCID: PMC4332208 - DOI: 10.14814/phy2.12226
Alieva M, Ritsma L, Giedt RJ, Weissleder R, van Rheenen J Imaging windows for long-term intravital imaging: general overview Intravital. 2014;3:2: e29917
Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, Kiss J, Selt F, Konrad C, Lodrini M, Deubzer HE, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma. Acta Neuropathol Commun. 2015;3(1):22 - PMID: 25853389 - PMCID: PMC4382927 - DOI: 10.1186/s40478-015-0201-7
Stone JR Diagnostic Biopsies of the Native Heart. Surg Pathol Clin. 2012;5(2):401-16 - PMID: 26838110 - DOI: 10.1016/j.path.2012.04.004
Miller M, Feng X, Li G, Rabitz H Nonlinear bionetwork structure inference using the random sampling-high dimensional model representation (RS-HDMR) algorithm. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6412-5 - PMID: 19964421 - DOI: 10.1109/IEMBS.2009.5333798
Im H, Wittenberg NJ, Lindquist NC, Oh SH Atomic layer deposition (ALD): A versatile technique for plasmonics and nanobiotechnology. J Mater Res. 2012;27(4):663-671 - PMID: 22865951 - PMCID: PMC3410655 - DOI: 10.1557/jmr.2011.434
Bantz KC, Meyer AF, Wittenberg NJ, Im H, Kurtuluş O, Lee SH, Lindquist NC, Oh SH, Haynes CL Recent progress in SERS biosensing. Phys Chem Chem Phys. 2011;13(24):11551-67 - PMID: 21509385 - PMCID: PMC3156086 - DOI: 10.1039/c0cp01841d
Im H, Wittenberg NJ, Lesuffleur A, Lindquist NC, Oh SH Membrane protein biosensing with plasmonic nanopore arrays and pore-spanning lipid membranes. Chem Sci. 2010;1(6):688-696 - PMID: 21218136 - PMCID: PMC3015192 - DOI: 10.1039/C0SC00365D
Lesuffleur A, Lim KS, Lindquist NC, Im H, Warrington AE, Rodriguez M, Oh SH Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1481-4 - PMID: 19963504 - DOI: 10.1109/IEMBS.2009.5332429
Huang X, Im H, Yarimaga O, Kim J, Jang D, Lee D, Kim H, Choi Y Electrochemical behavior of needle-like and forest-like single-walled carbon nanotube electrodes J Electroanal Chem. 2006;594(1):27-34
Huang X, Choi Y, Im H, Yarimaga O, Yoon E, Kim H Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques Sensors. 2006;6(7):756–782 - PMCID: PMC3894536
Naxerova K, Jain RK Using tumour phylogenetics to identify the roots of metastasis in humans. Nat Rev Clin Oncol. 2015;12(5):258-72 - PMID: 25601447 - DOI: 10.1038/nrclinonc.2014.238
Rogers MS, Novak K, Zurakowski D, Cryan LM, Blois A, Lifshits E, Bø TH, Oyan AM, Bender ER, Lampa M, Kang SY, Naxerova K, Kalland KH, Straume O, Akslen LA, Watnick RS, Folkman J, Naumov GN Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Mol Cancer Res. 2014;12(5):754-64 - PMID: 24574516 - PMCID: PMC4020951 - DOI: 10.1158/1541-7786.MCR-13-0532-T
Pai SI HPV-associated head and neck cancers. Otolaryngol Clin North Am. 2012;45(4):xi-xii - PMID: 22793861 - DOI: 10.1016/j.otc.2012.05.003
Pierce RH, Campbell JS, Pai SI, Brody JD, Kohrt HE In-situ tumor vaccination: Bringing the fight to the tumor. Hum Vaccin Immunother. 2015;11(8):1901-9 - PMID: 26055074 - PMCID: PMC4635874 - DOI: 10.1080/21645515.2015.1049779
Pai SI, Tufano RP Reoperation for recurrent/persistent well-differentiated thyroid cancer. Otolaryngol Clin North Am. 2010;43(2):353-63, ix - PMID: 20510718 - DOI: 10.1016/j.otc.2010.02.004
Loyo M, Pai SI The molecular genetics of laryngeal cancer. Otolaryngol Clin North Am. 2008;41(4):657-72, v - PMID: 18570952 - DOI: 10.1016/j.otc.2008.01.019
Wu AA, Niparko KJ, Pai SI Immunotherapy for head and neck cancer. J Biomed Sci. 2008;15(3):275-89 - PMID: 18392689 - DOI: 10.1007/s11373-008-9247-x
Tufano RP, Pai SI Thyroid and parathyroid surgery. Preface. Otolaryngol Clin North Am. 2010;43(2):xiii-xiv - PMID: 20510709 - DOI: 10.1016/j.otc.2010.04.001
Best SR, Niparko KJ, Pai SI Biology of human papillomavirus infection and immune therapy for HPV-related head and neck cancers. Otolaryngol Clin North Am. 2012;45(4):807-22 - PMID: 22793854 - PMCID: PMC3398423 - DOI: 10.1016/j.otc.2012.04.005
Pai SI, Tufano RP Central compartment neck dissection for thyroid cancer. Technical considerations. ORL J Otorhinolaryngol Relat Spec. 2008;70(5):292-7 - PMID: 18971593 - DOI: 10.1159/000149831
Gooi Z, Ward BK, Mener DJ, Ozgursoy OB, Pai SI A staged thyroidectomy approach for gastric bypass patients. Laryngoscope. 2014;125(4):1028-30 - PMID: 25043176 - DOI: 10.1002/lary.24835
Bishop JA, Guo TW, Smith DF, Wang H, Ogawa T, Pai SI, Westra WH Human papillomavirus-related carcinomas of the sinonasal tract. Am J Surg Pathol. 2013;37(2):185-92 - PMID: 23095507 - PMCID: PMC3545097 - DOI: 10.1097/PAS.0b013e3182698673
Ahn J, Bishop JA, Akpeng B, Pai SI, Best SR Xenograft model for therapeutic drug testing in recurrent respiratory papillomatosis. Ann Otol Rhinol Laryngol. 2014;124(2):110-5 - PMID: 25124839 - PMCID: PMC7423457 - DOI: 10.1177/0003489414546400
Pai SI Adaptive immune resistance in HPV-associated head and neck squamous cell carcinoma. OncoImmunology. 2013;2(5):e24065 - PMID: 23762795 - PMCID: PMC3667901 - DOI: 10.4161/onci.24065
Dʼsouza G, Carey TE, William WN, Nguyen ML, Ko EC, Riddell J, Pai SI, Gupta V, Walline HM, Lee JJ, Wolf GT, Shin DM, Grandis JR, Ferris RL Epidemiology of head and neck squamous cell cancer among HIV-infected patients. J Acquir Immune Defic Syndr. 2014;65(5):603-10 - PMID: 24326607 - PMCID: PMC3999230 - DOI: 10.1097/QAI.0000000000000083
Lin BM, Wang H, D'Souza G, Zhang Z, Fakhry C, Joseph AW, Drake VE, Sanguineti G, Westra WH, Pai SI Long-term prognosis and risk factors among patients with HPV-associated oropharyngeal squamous cell carcinoma. Cancer. 2013;119(19):3462-71 - PMID: 23861037 - PMCID: PMC3788050 - DOI: 10.1002/cncr.28250
Lyford-Pike S, Westra WH, Loyo M, Peng S, Hung CF, Wu AA, Flint PW, Tunkel DE, Saunders JR, Pai SI Differential expression of epidermal growth factor receptor in juvenile and adult-onset recurrent respiratory papillomatosis. Histopathology. 2010;57(5):768-70 - PMID: 21083608 - DOI: 10.1111/j.1365-2559.2010.03691.x
Wu G, Pai SI, Agrawal N, Richmon J, Dackiw A, Tufano RP Profile of patients with completion thyroidectomy and assessment of their suitability for outpatient surgery. Otolaryngol Head Neck Surg. 2011;145(5):727-31 - PMID: 21860058 - DOI: 10.1177/0194599811416749
Cho YG, Chang X, Park IS, Yamashita K, Shao C, Ha PK, Pai SI, Sidransky D, Kim MS Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma. Int J Oncol. 2011;39(2):337-44 - PMID: 21617854 - PMCID: PMC3601031 - DOI: 10.3892/ijo.2011.1050
Anderson KS, Wong J, D'Souza G, Riemer AB, Lorch J, Haddad R, Pai SI, Longtine J, McClean M, LaBaer J, Kelsey KT, Posner M Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer. Br J Cancer. 2011;104(12):1896-905 - PMID: 21654689 - PMCID: PMC3111202 - DOI: 10.1038/bjc.2011.171
Tsen SW, Wu CY, Meneshian A, Pai SI, Hung CF, Wu TC Femtosecond laser treatment enhances DNA transfection efficiency in vivo. J Biomed Sci. 2009;16:36 - PMID: 19338665 - PMCID: PMC2669473 - DOI: 10.1186/1423-0127-16-36
Loyo M, Pai SI, Netto GJ, Tunkel DE Aggressive recurrent respiratory papillomatosis in a neonate. Int J Pediatr Otorhinolaryngol. 2008;72(6):917-20 - PMID: 18423627 - DOI: 10.1016/j.ijporl.2008.02.022
Peng S, Best SR, Hung CF, Loyo M, Lyford-Pike S, Flint PW, Tunkel DE, Saunders JR, Wu TC, Pai SI Characterization of human papillomavirus type 11-specific immune responses in a preclinical model. Laryngoscope. 2010;120(3):504-10 - PMID: 20025042 - PMCID: PMC2908018 - DOI: 10.1002/lary.20745
Sedaghat AR, Zhang Z, Begum S, Palermo R, Best S, Ulmer KM, Levine M, Zinreich E, Messing BP, Gold D, Wu AA, Niparko KJ, Kowalski J, Hirata RM, Saunders JR, Westra WH, Pai SI Prognostic significance of human papillomavirus in oropharyngeal squamous cell carcinomas. Laryngoscope. 2009;119(8):1542-9 - PMID: 19522004 - DOI: 10.1002/lary.20533
Peng S, Lyford-Pike S, Akpeng B, Wu A, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine. Cancer Immunol Immunother. 2012;62(1):171-82 - PMID: 23011589 - PMCID: PMC3543472 - DOI: 10.1007/s00262-012-1322-5
Kim D, Hoory T, Monie A, Wu A, Hsueh WT, Pai SI, Hung CF Delivery of chemotherapeutic agents using drug-loaded irradiated tumor cells to treat murine ovarian tumors. J Biomed Sci. 2010;17:61 - PMID: 20659328 - PMCID: PMC2918546 - DOI: 10.1186/1423-0127-17-61
Jara SM, Carson KA, Pai SI, Agrawal N, Richmon JD, Prescott JD, Dackiw A, Zeiger MA, Bishop JA, Tufano RP The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma. Surgery. 2013;154(6):1272-80; discussion 1280-2 - PMID: 24238047 - DOI: 10.1016/j.surg.2013.07.021
Bishop JA, Ogawa T, Stelow EB, Moskaluk CA, Koch WM, Pai SI, Westra WH Human papillomavirus-related carcinoma with adenoid cystic-like features: a peculiar variant of head and neck cancer restricted to the sinonasal tract. Am J Surg Pathol. 2013;37(6):836-44 - PMID: 23598962 - PMCID: PMC3653997 - DOI: 10.1097/PAS.0b013e31827b1cd6
Park IS, Chang X, Loyo M, Wu G, Chuang A, Kim MS, Chae YK, Lyford-Pike S, Westra WH, Saunders JR, Sidransky D, Pai SI Characterization of the methylation patterns in human papillomavirus type 16 viral DNA in head and neck cancers. Cancer Prev Res (Phila). 2011;4(2):207-17 - PMID: 21292634 - PMCID: PMC3079312 - DOI: 10.1158/1940-6207.CAPR-10-0147
Flint PW, Li ZB, Lehar M, Saito K, Pai SI Laryngeal muscle surface receptors identified using random phage library. Laryngoscope. 2005;115(11):1930-7 - PMID: 16319601 - DOI: 10.1097/01.mlg.0000172273.98418.8d
Bishop JA, Ogawa T, Chang X, Illei PB, Gabrielson E, Pai SI, Westra WH HPV analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma. Am J Surg Pathol. 2012;36(1):142-8 - PMID: 22173119 - PMCID: PMC3273906 - DOI: 10.1097/PAS.0b013e3182395c7b
Best SR, Ha PK, Blanco RG, Saunders JR, Zinreich ES, Levine MA, Pai SI, Walker M, Trachta J, Ulmer K, Murakami P, Thompson R, Califano JA, Messing BP Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma. Head Neck. 2011;33(12):1727-34 - PMID: 21246640 - PMCID: PMC4695991 - DOI: 10.1002/hed.21657
Wu G, Fraser S, Pai SI, Farrag TY, Ladenson PW, Tufano RP Determining the extent of lateral neck dissection necessary to establish regional disease control and avoid reoperation after previous total thyroidectomy and radioactive iodine for papillary thyroid cancer. Head Neck. 2011;34(10):1418-21 - PMID: 22052539 - DOI: 10.1002/hed.21937
Hillel AT, Fakhry C, Pai SI, Williams MF, Blanco RG, Zinreich ES, Levine MA, Westra WH, Saunders JR, Ha PK Selective versus comprehensive neck dissection after chemoradiation for advanced oropharyngeal squamous cell carcinoma. Otolaryngol Head Neck Surg. 2009;141(6):737-42 - PMID: 19932847 - DOI: 10.1016/j.otohns.2009.09.010
Goldenberg D, Begum S, Westra WH, Khan Z, Sciubba J, Pai SI, Califano JA, Tufano RP, Koch WM Cystic lymph node metastasis in patients with head and neck cancer: An HPV-associated phenomenon. Head Neck. 2008;30(7):898-903 - PMID: 18383529 - DOI: 10.1002/hed.20796
Kim TW, Hung CF, Zheng M, Boyd DA, He L, Pai SI, Wu TC A DNA vaccine co-expressing antigen and an anti-apoptotic molecule further enhances the antigen-specific CD8+ T-cell immune response. J Biomed Sci. 2004;11(4):493-9 - PMID: 15153784 - DOI: 10.1007/BF02256098
Dong SM, Pai SI, Rha SH, Hildesheim A, Kurman RJ, Schwartz PE, Mortel R, McGowan L, Greenberg MD, Barnes WA, Sidransky D Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma. Cancer Epidemiol Biomarkers Prev. 2002;11(1):3-6 - PMID: 11815394
Cheng WF, Hung CF, Pai SI, Hsu KF, He L, Ling M, Wu TC Repeated DNA vaccinations elicited qualitatively different cytotoxic T lymphocytes and improved protective antitumor effects. J Biomed Sci. 2002;9(6 Pt 2):675-87 - PMID: 12432234 - DOI: 10.1159/000067285
Pai SI, Limb CJ, Nicol T, Williams MF Leiomyosarcoma of the auricle. Otolaryngol Head Neck Surg. 2003;128(3):442-4 - PMID: 12646855 - DOI: 10.1067/mhn.2003.16
Lin LM, Pai SI, Flint PW A retropharyngeal pseudoabscess in a patient with paroxysmal nocturnal hemoglobinuria. Otolaryngol Head Neck Surg. 2007;137(4):684-6 - PMID: 17903595 - DOI: 10.1016/j.otohns.2007.01.032
Nichols RC, Blinder J, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P Assignment of two human autoantigen genes-isoleucyl-tRNA synthetase locates to 9q21 and lysyl-tRNA synthetase locates to 16q23-q24. Genomics. 1996;36(1):210-3 - PMID: 8812440 - DOI: 10.1006/geno.1996.0449
Nichols RC, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P Localization of two human autoantigen genes by PCR screening and in situ hybridization--glycyl-tRNA synthetase locates to 7p15 and alanyl-tRNA synthetase locates to 16q22. Genomics. 1995;30(1):131-2 - PMID: 8595897 - DOI: 10.1006/geno.1995.0028
Pai SI, Goldstein BJ, Studeman KD, Westra WH, Tufano RP Concurrent sporadic parathyroid adenoma and carcinoma. Am J Otolaryngol. 2006;27(5):346-8 - PMID: 16935182 - DOI: 10.1016/j.amjoto.2005.11.017
Friedmann AS, Malott KA, Memoli VA, Pai SI, Yu XM, North WG Products of vasopressin gene expression in small-cell carcinoma of the lung. Br J Cancer. 1994;69(2):260-3 - PMID: 8297723 - PMCID: PMC1968694 - DOI: 10.1038/bjc.1994.49
Garris CS, Blaho VA, Hla T, Han MH Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond. Immunology. 2014;142(3):347-53 - PMID: 24597601 - PMCID: PMC4080950 - DOI: 10.1111/imm.12272
Hackney JA, Misaghi S, Senger K, Garris C, Sun Y, Lorenzo MN, Zarrin AA DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination. Adv Immunol. 2009;101:163-89 - PMID: 19231595 - DOI: 10.1016/S0065-2776(08)01005-5
Szu H, Hwang WL Self-supervised backpropagation in stem cells IEEE Connections. 2003;1(3):8-9
Su F, Hwang WL, Mukherjee A, Chakrabarty K Testing and diagnosis of realistic defects in digital microfluidic biochips Journal of Electronic Testing. 2007;23(2-3):219-33
Xu T, Hwang WL, Su F, Chakrabarty K. Automated design of pin-constrained digital microfluidic biochips under droplet-interference constraints Journal on Emerging Technologies in Computing. 2007;3(3):14