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Bone Marrow Stromal Cell Transplants Prevent Experimental Enterocolitis and Require Host CD11b+ Splenocytes. Gastroenterology. 2010;140(3):966-975.e4 - PMID: 20955701 - PMCID: PMC3033974 - DOI: 10.1053/j.gastro.2010.10.013

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Molecular Imaging in the Clinical Arena JAMA. 2005;293(7):855-62 - PMID: 15713776 - DOI: 10.1001/jama.293.7.855

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Shedding light onto live molecular targets Nature Med. 2003;9:123-8 - PMID: 12514725 - DOI: 10.1038/nm0103-123

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Fluorescence molecular tomography resolves protease activity in vivo Nature Med. 2002;8:757-60 - PMID: 12091907 - DOI: 10.1038/nm729

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nature Med. 2008;14(12)::1351-1356 - PMID: 19029981 - PMCID: PMC2683415 - DOI: 10.1038/nm.1890

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In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation Nature Med. 2011;17(9):1142-6 - PMID: 21857652 - PMCID: PMC3169740 - DOI: 10.1038/nm.2423

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Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques. Circulation. 2009;120(7):592-9 - PMID: 19652086 - PMCID: PMC2736635 - DOI: 10.1161/CIRCULATIONAHA.108.813998

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High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis. Circulation. 2010;122(17):1707-15 - PMID: 20937980 - PMCID: PMC3003265 - DOI: 10.1161/CIRCULATIONAHA.109.891804

Sakhuja R, Suh WM, Jaffer FA, Jang IK

Residual Thrombogenic Substrate After Rupture of a Lipid-Rich Plaque: Possible Mechanism of Acute Stent Thrombosis? Circulation. 2010;122(22):2349-2350 - PMID: 21147731 - DOI: 10.1161/CIRCULATIONAHA.110.970079

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Report of the national heart, lung, and blood institute working group on the translation of cardiovascular molecular imaging. Circulation. 2011;123(19):2157-63 - PMID: 21576680 - PMCID: PMC3119488 - DOI: 10.1161/CIRCULATIONAHA.110.000943

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Robbins CS, Chudnovskiy A, Rauch PJ, Figueiredo JL, Iwamoto Y, Gorbatov R, Etzrodt M, Weber GF, Ueno T, van Rooijen N, Mulligan-Kehoe MJ, Libby P, Nahrendorf M, Pittet MJ, Weissleder R, Swirski FK

Extramedullary Hematopoiesis Generates Ly-6Chigh Monocytes that Infiltrate Atherosclerotic Lesions. Circulation. 2011;125(2):364-74 - PMID: 22144566 - PMCID: PMC3263762 - DOI: 10.1161/CIRCULATIONAHA.111.061986

Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R

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Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R

Molecular Imaging of Factor XIIIa Activity in Thrombosis Using a Novel, Near-Infrared Fluorescent Contrast Agent That Covalently Links to Thrombi. Circulation. 2004;110(2):170-6 - PMID: 15210587 - DOI: 10.1161/01.CIR.0000134484.11052.44

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Near-Infrared Fluorescent Imaging of Matrix Metalloproteinase Activity After Myocardial Infarction Circulation. 2005;111:1800-1805 - PMID: 15809374 - PMCID: PMC3733536 - DOI: 10.1161/01.CIR.0000160936.91849.9F

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Factor XIII Deficiency Causes Cardiac Rupture, Impairs Wound Healing, and Aggravates Cardiac Remodeling in Mice with Myocardial Infarction Circulation. 2006;113(9):1196-1202 - PMID: 16505171 - PMCID: PMC4066325 - DOI: 10.1161/CIRCULATIONAHA.105.602094

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Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells. Circulation. 2006;113(19):2301-12 - PMID: 16682613 - DOI: 10.1161/CIRCULATIONAHA.105.605121

Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P

Inflammation in Atherosclerosis. Visualizing Matrix Metalloproteinase Action in Macrophages In Vivo. Circulation. 2006;114:55-62 - PMID: 16801460 - DOI: 10.1161/CIRCULATIONAHA.106.619056

Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R

Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis. Circulation. 2006;114:1504-1511 - PMID: 17000904 - DOI: 10.1161/CIRCULATIONAHA.106.646380

Aikawa E, Nahrendorf M, Sosnovik D, Lok VM, Jaffer FA, Aikawa M, Weissleder R

Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease. Circulation. 2007;115:377-386 - PMID: 17224478 - DOI: 10.1161/CIRCULATIONAHA.106.654913

Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V

Fluorescence Tomography and Magnetic Resonance Imaging of Myocardial Macrophage Infiltration in Infarcted Myocardium In Vivo. Circulation. 2007;115:1384-1391 - PMID: 17339546 - DOI: 10.1161/CIRCULATIONAHA.106.663351

Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, Weissleder R

Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor. Circulation. 2007;115(17):2292-8 - PMID: 17420353 - DOI: 10.1161/CIRCULATIONAHA.106.660340

Sosnovik DE, Nahrendorf M, Weissleder R

Molecular magnetic resonance imaging in cardiovascular medicine. Circulation. 2007;115(15):2076-86 - PMID: 17438163 - DOI: 10.1161/CIRCULATIONAHA.106.658930

Jaffer FA, Libby P, Weissleder R

Molecular imaging of cardiovascular disease. Circulation. 2007;116(9):1052-61 - PMID: 17724271 - DOI: 10.1161/CIRCULATIONAHA.106.647164

Aikawa E, Nahrendorf M, Figueiredo JL, Swirski F, Shtatland T, Kohler RH, Jaffer F, Aikawa M, Weissleder R.

Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation. 2007;116(24):2841-50 - PMID: 18040026 - DOI: 10.1161/CIRCULATIONAHA.107.732867

Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik D, Aikawa E, Libby P, Swirski F, Weissleder R.

Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis Circulation. 2007;117:379-387 - PMID: 18158358 - PMCID: PMC2663426 - DOI: 10.1161/CIRCULATIONAHA.107.741181

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Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions. Circulation. 2008;117:388-395 - PMID: 18172031 - PMCID: PMC2705289 - DOI: 10.1161/CIRCULATIONAHA.107.719765

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Activatable Magnetic Resonance Imaging Agent Reports Myeloperoxidase Activity in Healing Infarcts and Noninvasively Detects the Antiinflammatory Effects of Atorvastatin on Ischemia-Reperfusion Injury. Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051 - DOI: 10.1161/CIRCULATIONAHA.107.756510

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Lindsey M, Gannon J, Aikawa M, Schoen F, Rabkin E, Lopresti-Morrow L, Crawford J, Black S, Libby P, Mitchell P, Lee R

Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction. Circulation. 2002;105:753-8 - PMID: 11839633 - DOI: 10.1161/hc0602.103674

Larose E, Yeghiazarians Y, Libby P, Yucel E, Aikawa M, Kacher D, Aikawa E, Kinlay S, Schoen F, Selwyn A, Ganz P

Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging. Circulation. 2005;112:2324-31 - PMID: 16203910 - DOI: 10.1161/CIRCULATIONAHA.105.538942

Heller E, Liu E, Tager A, Sinha S, Roberts J, Koehn S, Libby P, Aikawa E, Chen J, Huang P, Freeman M, Moore K, Luster A, Gerszten R

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation. 2005;112:578-86 - PMID: 16043658 - DOI: 10.1161/CIRCULATIONAHA.105.545616

Sutherland F, Perry T, Yu Y, Sherwood M, Rabkin E, Masuda Y, Garcia G, McLellan D, Engelmayr G, Sacks M, Schoen F, Mayer J

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Fukumoto Y, Deguchi J, Libby P, Rabkin-Aikawa E, Sakata Y, Chin M, Hill C, Lawler P, Varo N, Schoen F, Krane S, Aikawa M

Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques. Circulation. 2004;110:1953-9 - PMID: 15451791 - DOI: 10.1161/01.CIR.0000143174.41810.10

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Rabkin E, Aikawa M, Stone J, Fukumoto Y, Libby P, Schoen F

Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation. 2001;104:2525-32 - PMID: 11714645 - DOI: 10.1161/hc4601.099489

Aikawa M, Rabkin E, Sugiyama S, Voglic S, Fukumoto Y, Furukawa Y, Shiomi M, Schoen F, Libby P

An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation. 2001;103:276-83 - PMID: 11208689 - DOI: 10.1161/01.cir.103.2.276

Fukumoto Y, Libby P, Rabkin E, Hill C, Enomoto M, Hirouchi Y, Shiomi M, Aikawa M

Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. Circulation. 2001;103:993-9 - PMID: 11181475 - DOI: 10.1161/01.cir.103.7.993

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Aikawa M, Rabkin E, Okada Y, Voglic S, Clinton S, Brinckerhoff C, Sukhova G, Libby P

Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization. Circulation. 1998;97:2433-44 - PMID: 9641696 - DOI: 10.1161/01.cir.97.24.2433

Nakagawa T, Sukhova G, Rabkin E, Winters G, Schoen F, Libby P

Acute rejection accelerates graft coronary disease in transplanted rabbit hearts. Circulation. 1995;92:987-93 - PMID: 7641383 - DOI: 10.1161/01.cir.92.4.987

Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R

Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis. Circulation. 2008;118(18):1802-9 - PMID: 18852366 - PMCID: PMC2729441 - DOI: 10.1161/CIRCULATIONAHA.108.785881

Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R

Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease. Circulation. 2009;119(13):1785-94 - PMID: 19307473 - PMCID: PMC2717745 - DOI: 10.1161/CIRCULATIONAHA.108.827972

Christen T*, Nahrendorf M*, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P

Molecular Imaging of Innate Immune Cell Function in Transplant Rejection. Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889 - DOI: 10.1161/CIRCULATIONAHA.108.796888

Liong M, Shao H, Haun JB, Lee H, Weissleder R

Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications. Adv Mater. 2010;22(45):5168-72 - PMID: 20859943 - PMCID: PMC2993874 - DOI: 10.1002/adma.201002219

Liong M, Tassa C, Shaw SY, Lee H, Weissleder R

Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization. Adv Mater. 2011;23(36):H254-7 - PMID: 21780311 - PMCID: PMC3584698 - DOI: 10.1002/adma.201101401

Yoon TJ*, Lee H*, Shao H, Hilderbrand SA, Weissleder R

Multicore Assemblies Potentiate Magnetic Properties of Biomagnetic Nanoparticles. Adv Mater. 2011;23(41):4793-7 - PMID: 21953810 - PMCID: PMC3224986 - DOI: 10.1002/adma.201102948

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Loss of adenomatous polyposis coli gene function disrupts thymic development Nat Immunol. 2005;6(8):800-9 - PMID: 16025118 - PMCID: PMC4662936 - DOI: 10.1038/ni1228

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Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006;7(3):284-92 - PMID: 16444258 - DOI: 10.1038/ni1306

Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Cote D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood. 2007;109:2708-17 - PMID: 17119115 - PMCID: PMC1852222 - DOI: 10.1182/blood-2006-07-035857

Leleu X, Jia X, Runnels J, Ngo HT, Moreau AS, Farag M, Spencer JA, Pitsillides CM, Hatjiharissi E, Roccaro A, O'Sullivan G, McMillin DW, Moreno D, Kiziltepe T, Carrasco R, Treon SP, Hideshima T, Anderson KC, Lin CP, Ghobrial IM

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia. Blood. 2007;110:4417-26 - PMID: 17761832 - PMCID: PMC2234792 - DOI: 10.1182/blood-2007-05-092098

Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood. 2008;111(10):5195-204 - PMID: 18326817 - PMCID: PMC2384142 - DOI: 10.1182/blood-2007-09-111567

Rufer N, Zippelius A, Batard P, Pittet M, Kurth I, Corthesy P, Cerottini J, Leyvraz S, Roosnek E, Nabholz M, Romero P

Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood. 2003;102:1779-87 - PMID: 12750165 - DOI: 10.1182/blood-2003-02-0420

Kerre T, De Smet G, De Smedt M, Zippelius A, Pittet M, Langerak A, De Bosscher J, Offner F, Vandekerckhove B, Plum J

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells. Blood. 2002;99:1620-6 - PMID: 11861276 - DOI: 10.1182/blood.v99.5.1620

Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM

microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922 - DOI: 10.1182/blood-2009-01-198408

Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM

Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma. Blood. 2009;114(3):619-29 - PMID: 19443661 - PMCID: PMC2713475 - DOI: 10.1182/blood-2009-01-199281

Azab A, Runnels J, Pitsillides C, Moreau A, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson A, Alt C, Burwick N, Roccaro A, Ngo H, Farag M, Melhem M, Sacco A, Munshi N, Hideshima T, Rollins B, Anderson K, Kung A, Lin CP, Ghobrial I

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood. 2009;113:4341-51 - PMID: 19139079 - PMCID: PMC2676090 - DOI: 10.1182/blood-2008-10-186668

Kunstfeld R, Hirakawa S, Hong Y-K, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin CP, Fiebiger E, Wu Y, Hicklin D, Bohlen P, Detmar M

VEGF-A overexpression leads to lymphatic vessel enlargement and persistent skin inflammation Blood. 2004;104:1048-57

Higgins JM, Sloan SR

Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders. Blood. 2008;112(6):2546-53 - PMID: 18535200 - DOI: 10.1182/blood-2008-03-146415

Higgins JM, Sloan SR

Response: Other factors may contribute to differences between sickle cell and non-sickle cell patients. Blood. 2010;115(21):4315-6 - PMID: 20508172

Meynard D, Vaja V, Sun CC, Corradini E, Chen S, Lopez-Otin C, Grgurevic L, Hong CC, Stirnberg M, Gutschow M, Vukicevic S, Babitt JL, Lin HY

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice. Blood. 2011;118(3):747-56 - PMID: 21622652 - PMCID: PMC3142910 - DOI: 10.1182/blood-2011-04-348698

Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, Willenbacher W, Eller K, Wolf D, Seifert M, Sun CC, Babitt JL, Hong CC, Menhall T, Gearing P, Lin HY, Weiss G

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic disease in rats. Blood. 2011;118(18):4977-84 - PMID: 21730356 - PMCID: PMC3208302 - DOI: 10.1182/blood-2011-03-345066

Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA

Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood. 2011;118(10):2849-56 - PMID: 21765021 - PMCID: PMC3172801 - DOI: 10.1182/blood-2011-03-345165

Sarkar D, Spencer JA, Phillips JA, Zhao W, Schafer S, Spelke DP, Mortensen LJ, Ruiz JP, Vemula PK, Sridharan R, Kumar S, Karnik R, Lin CP, Karp JM

Engineered cell homing. Blood. 2011;118(25):e184-91 - PMID: 22034631 - PMCID: PMC3242725 - DOI: 10.1182/blood-2010-10-311464

Maiso P, Liu Y, Morgan B, Azab A, Ren P, Martin MB, Zhang Y, Liu Y, Sacco A, Ngo H, Azab F, Quang P, Rodig SJ, Lin CP, Roccaro A, Rommel C, Ghobrial IM

Defining the role of TORC1 and TORC2 in multiple myeloma. Blood. 2011;118(26):6860-70 - PMID: 22045983 - PMCID: PMC3245208 - DOI: 10.1182/blood-2011-03-342394

Azab AK, Quang P, Azab F, Pitsillides C, Thompson B, Chonghaile T, Patton JT, Maiso P, Monrose V, Sacco A, Ngo HT, Flores LM, Lin CP, Magnani JL, Kung AL, Letai A, Carrasco R, Roccaro AM, Ghobrial IM

P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment. Blood. 2011;119(6):1468-78 - PMID: 22096244 - PMCID: PMC3286211 - DOI: 10.1182/blood-2011-07-368050

Mosley AJ, Meekings KN, McCarthy C, Shepherd D, Cerundolo V, Mazitschek R, Tanaka Y, Taylor GP, Bangham CR

Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection. Blood. 2006;108(12):3801-7 - PMID: 16912225 - DOI: 10.1182/blood-2006-03-013235

Nicolaou F, Teodoridis JM, Park H, Georgakis A, Farokhzad OC, Böttinger EP, Da Silva N, Rousselot P, Chomienne C, Ferenczi K, Arnaout MA, Shelley CS

CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD. Blood. 2003;101(10):4033-41 - PMID: 12576324 - DOI: 10.1182/blood-2002-01-0324

Da Silva N, Bharti A, Shelley CS

hnRNP-K and Pur(alpha) act together to repress the transcriptional activity of the CD43 gene promoter. Blood. 2002;100(10):3536-44 - PMID: 12411317 - DOI: 10.1182/blood.V100.10.3536

Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE

Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network. Cell Stem Cell. 2010;6(6):591-602 - PMID: 20569696 - PMCID: PMC2897075 - DOI: 10.1016/j.stem.2010.03.016

Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A

Reprogramming factor expression initiates widespread targeted chromatin remodeling. Cell Stem Cell. 2011;8(1):96-105 - PMID: 21211784 - PMCID: PMC3220622 - DOI: 10.1016/j.stem.2010.12.001

Devaraj NK, Weissleder R

Biomedical Applications of Tetrazine Cycloadditions. Accounts Chem Res. 2011;44(9):816-27 - PMID: 21627112 - PMCID: PMC3166440 - DOI: 10.1021/ar200037t

Tassa C, Shaw SY, Weissleder R

Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy. Accounts Chem Res. 2011;44(10):842-52 - PMID: 21661727 - PMCID: PMC3182289 - DOI: 10.1021/ar200084x

Hurtado-Lorenzo A, Skinner M, El Annan J, Futai M, Sun-Wada GH, Bourgoin S, Casanova J, Wildeman A, Bechoua S, Ausiello DA, Brown D, Marshansky V

V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat Cell Biol. 2006;8(2):124-36 - PMID: 16415858 - DOI: 10.1038/ncb1348

Jaffer F, Libby P, Weissleder R.

Molecular and Cellular Imaging of Atherosclerosis, Emerging Applications J Am Coll Cardiol. 2006;47:1328-1338 - PMID: 16580517 - DOI: 10.1016/j.jacc.2006.01.029

Nahrendorf M, Hu K, Hiller K, Galuppo P, Fraccarollo D, Schweizer G, Haase A, Ertl G, Bauer W, Bauersachs J

Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study. J Am Coll Cardiol. 2002;40(9):1695-700 - PMID: 12427425 - DOI: 10.1016/s0735-1097(02)02375-6

Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schar M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M

Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using positive contrast magnetic resonance imaging. J Am Coll Cardiol. 2008;52:483-91 - PMID: 18672170 - PMCID: PMC2628468 - DOI: 10.1016/j.jacc.2008.03.063

Jaffer FA

Assessing niacin as an atherosclerosis therapeutic agent valuable insights provided by high-resolution vascular magnetic resonance imaging. J Am Coll Cardiol. 2009;54(19):1795-6 - PMID: 19874993 - DOI: 10.1016/j.jacc.2009.07.026

Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J Am Coll Cardiol. 2010;55(15):1629-38 - PMID: 20378083 - PMCID: PMC2852892 - DOI: 10.1016/j.jacc.2009.08.089

Jaffer FA, Calfon MA, Rosenthal A, Mallas G, Razansky RN, Mauskapf A, Weissleder R, Libby P, Ntziachristos V

Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury. J Am Coll Cardiol. 2011;57(25):2516-26 - PMID: 21679853 - PMCID: PMC3123768 - DOI: 10.1016/j.jacc.2011.02.036

Atri M, Zhang Z, Marques H, Gorelick J, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Gold M,

Utility of preoperative ferumoxtran-10 enhanced MRI to evaluate retroperitoneal lymph node metastasis in advanced cervical cancer: Results of ACRIN 6671/GOG 0233. J Clin Oncol. 2011;29(15_suppl):5035 - PMID: 28023716

Gold M, Zhang Z, Marques H, Gorelick J, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Atri M

MRI prior to systematic lymphadenectomy in patients with locally advanced cervical cancer. J Clin Oncol. 2011;29(15_suppl):5042 - PMID: 28023697

Santo L, Hideshima T, Kung AL, Yang M, Tamang D, Jarpe M, van Duzer JH, Mazitschek R, Cirstea D, Patel K, Tseng J, Rodig S, Pozzi S, Bradner J, Anderson KC, Jones SS, Raje NS

The effect of selective inhibition of HDAC6 with ACY1215 on bortezomib activity in multiple myeloma (MM). J Clin Oncol. 2011;29(15_suppl):e18569 - PMID: 28023028

Haun JB*, Castro CM*, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R.

Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples Sci Transl Med. 2011;3(71):71ra16 - PMID: 21346169 - PMCID: PMC3086073 - DOI: 10.1126/scitranslmed.3002048

Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA

Indocyanine Green Enables Near-Infrared Fluorescence Imaging of Lipid-Rich, Inflamed Atherosclerotic Plaques Sci Transl Med. 2011;3 (84) ra45):84ra45 - PMID: 21613624 - PMCID: PMC3112179 - DOI: 10.1126/scitranslmed.3001577

Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT

Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Transl Med. 2011;3(104):104ra101 - PMID: 21998408 - PMCID: PMC3754876 - DOI: 10.1126/scitranslmed.3002191

Lee H*, Yoon TJ*, Weissleder R

Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System. Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069 - DOI: 10.1002/anie.200901791

Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition. Angew Chem Int Ed Engl. 2009;48(38):7013-6 - PMID: 19697389 - PMCID: PMC2790075 - DOI: 10.1002/anie.200903233

Georgakoudi I, Solban N, Novak J, Rice WL, Wei X, Hasan T, Lin CP

In vivo flow cytometry: a new method for enumerating circulating cancer cells. Cancer Res. 2004;64(15):5044-7 - PMID: 15289300 - PMCID: PMC2824432 - DOI: 10.1158/0008-5472.CAN-04-1058

Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R

Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells. Angew Chem Int Ed Engl. 2010;19 (49):2869-2872 - PMID: 20306505 - PMCID: PMC3433403 - DOI: 10.1002/anie.200906120

Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, Fisher PB, Sarkar D

Molecular Mechanism of Chemoresistance by Astrocyte Elevated Gene-1. Cancer Res. 2010;70(8):3249-58 - PMID: 20388796 - PMCID: PMC2855753 - DOI: 10.1158/0008-5472.CAN-09-4009

Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Aleman JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR

The Phosphoinositide 3-Kinase Regulatory Subunit p85{alpha} Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling. Cancer Res. 2010;70(13):5305-5315 - PMID: 20530665 - PMCID: PMC3204358 - DOI: 10.1158/0008-5472.CAN-09-3399

Bagci-Onder T, Wakimoto H, Anderegg M, Cameron C, Shah K

A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell delivered TRAIL in experimental glioma models. Cancer Res. 2010;71(1):154-63 - PMID: 21084267 - DOI: 10.1158/0008-5472.CAN-10-1601

Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R

Synthesis and In Vivo Imaging of a (18) F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method. Angew Chem Int Ed Engl. 2011;50(8):1922-5 - PMID: 21328671 - PMCID: PMC3471140 - DOI: 10.1002/anie.201006579

Yoon TJ*, Lee H*, Shao H, Weissleder R

Highly magnetic core-shell nanoparticles with a unique magnetization mechanism. Angew Chem Int Ed Engl. 2011;50(20):4663-6 - PMID: 21495138 - PMCID: PMC3334859 - DOI: 10.1002/anie.201100101

Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ

Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics. Cancer Res. 2011;71(13):4608-16 - PMID: 21712408 - PMCID: PMC3129392 - DOI: 10.1158/0008-5472.CAN-11-0412

Budin G, Yang KS, Reiner T, Weissleder R

Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification. Angew Chem Int Ed Engl. 2011;50(40):9378-81 - PMID: 21948435 - PMCID: PMC3187564 - DOI: 10.1002/anie.201103273

Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R

Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers. Angew Chem Int Ed Engl. 2011;51(2):450-4 - PMID: 22113923 - PMCID: PMC3309171 - DOI: 10.1002/anie.201105670

Karver MR, Weissleder R, Hilderbrand SA

Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging. Angew Chem Int Ed Engl. 2011;51(4):920-2 - PMID: 22162316 - PMCID: PMC3304098 - DOI: 10.1002/anie.201104389

Rosenbaum C, Baumhof P, Mazitschek R, Müller O, Giannis A, Waldmann H

Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors. Angew Chem Int Ed Engl. 2004;43(2):224-8 - PMID: 14695616 - DOI: 10.1002/anie.200352582

Huwe A, Mazitschek R, Giannis A

Small molecules as inhibitors of cyclin-dependent kinases. Angew Chem Int Ed Engl. 2003;42(19):2122-38 - PMID: 12761741 - DOI: 10.1002/anie.200200540

Stahl P, Kissau L, Mazitschek R, Giannis A, Waldmann H

Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors. Angew Chem Int Ed Engl. 2002;41(7):1174-8 - PMID: 12491250 - DOI: 10.1002/1521-3773(20020402)41:7<1174::aid-anie1174>3.0.co;2-v

Stieber F, Mazitschek R, Soric N, Giannis A, Waldmann H

Traceless solid-phase synthesis of 2-aminothiazoles: receptor tyrosine kinase inhibitors with dual selectivity for Tie-2 and VEGFR-2. Angew Chem Int Ed Engl. 2002;41(24):4757-61 - PMID: 12481350 - DOI: 10.1002/anie.200290040

Mazitschek R, Mülbaier M, Giannis A

IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids. Angew Chem Int Ed Engl. 2002;41(21):4059-61 - PMID: 12412081 - DOI: 10.1002/1521-3773(20021104)41:21<4059::AID-ANIE4059>3.0.CO;2-R

Baumhof P, Mazitschek R, Giannis A

A Mild and Effective Method for the Transesterification of Carboxylic Acid Esters P.B. and R.M. are grateful to the Land Baden-Württemberg for a scholarship from the Landesgraduiertenförderung. Angew Chem Int Ed Engl. 2001;40(19):3672-3674 - PMID: 11592218 - DOI: 10.1002/1521-3773(20011001)40:19<3672::aid-anie3672>3.0.co;2-y

Wernert N, Stanjek A, Kiriakidis S, Hügel A, Jha HC, Mazitschek R, Giannis A

Inhibition of Angiogenesis In Vivo by ets-1 Antisense Oligonucleotides-Inhibition of Ets-1 Transcription Factor Expression by the Antibiotic Fumagillin. Angew Chem Int Ed Engl. 1999;38(21):3228-3231 - PMID: 10556911 - DOI: 10.1002/(sici)1521-3773(19991102)38:21<3228::aid-anie3228>3.0.co;2-8

Josephson L, Perez JM, Weissleder R

Magnetic Nanosensors for the Detection of Oligonucleotide Sequences. Angew Chem Int Ed Engl. 2001;40(17):3204-3206 - PMID: 29712059 - DOI: 10.1002/1521-3773(20010903)40:17<3204::AID-ANIE3204>3.0.CO;2-H

Kang TH, Noh KH, Kim JH, Bae HC, Lin KY, Monie A, Pai SI, Hung CF, Wu TC, Kim TW

Ectopic expression of X-linked lymphocyte-regulated protein pM1 renders tumor cells resistant to antitumor immunity. Cancer Res. 2010;70(8):3062-70 - PMID: 20395201 - PMCID: PMC2861497 - DOI: 10.1158/0008-5472.CAN-09-3856

Kang TH, Lee JH, Song CK, Han HD, Shin BC, Pai SI, Hung CF, Trimble C, Lim JS, Kim TW, Wu TC

Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination. Cancer Res. 2007;67(2):802-11 - PMID: 17234792 - PMCID: PMC3181129 - DOI: 10.1158/0008-5472.CAN-06-2638

Pai SI, Wu GS, Ozören N, Wu L, Jen J, Sidransky D, El-Deiry WS

Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 1998;58(16):3513-8 - PMID: 9721851

Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R

In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas Cancer Res. 2004;64:273-8 - PMID: 14729634 - DOI: 10.1158/0008-5472.can-03-1123

Grimm J, Perez JM, Josephson L, Weissleder R

Novel nanosensors for rapid analysis of telomerase activity Cancer Res. 2004;64:639-43 - PMID: 14744779 - DOI: 10.1158/0008-5472.can-03-2798

Zhao M, Josephson L, Tang Y, Weissleder R

Magnetic sensors for protease assays Angew Chem Int Ed Engl. 2003;42:1375-8 - PMID: 12671972 - DOI: 10.1002/anie.200390352

Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A Jr

Near-infrared fluorescent imaging of tumor apoptosis Cancer Res. 2003;63:1936-42 - PMID: 12702586

Kircher MF, Allport, JR, Graves EE, Love V, Josephson L, Lichtman AH, Weissleder R

In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors Cancer Res. 2003;63:6838-46 - PMID: 14583481

Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L

A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation Cancer Res. 2003;63:8122-5 - PMID: 14678964

Pham W, Weissleder R, Tung CH

An azulene dimer as a near-infrared quencher Angew Chem Int Ed Engl. 2002;41:3659-62, 3519 - PMID: 12370922 - DOI: 10.1002/1521-3773(20021004)41:19<3659::AID-ANIE3659>3.0.CO;2-Q

Tung CH, Mahmood U, Bredow S, Weissleder R

In vivo imaging of proteolytic enzyme activity using a novel molecular reporter Cancer Res. 2000;60:4953-8 - PMID: 10987312

Simonova M, Wall A, Weissleder R, Bogdanov A Jr

Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells Cancer Res. 2000;60:6656-62 - PMID: 11118049

Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout D, Weissleder R

In Vivo Imaging of ?-Galactosidase Activity Using Far Red Fluorescent Switch Cancer Res. 2004;64:1579-1583 - PMID: 14996712 - DOI: 10.1158/0008-5472.can-03-3226

Tsourkas A, Hofstetter O, Hofstetter H, Weissleder R, Josephson L

Magnetic Relaxation Switch Immunosensors Detect Enantiomeric Impurities Angew Chem Int Ed Engl. 2004;43(18):2395-2399 - PMID: 15114571 - DOI: 10.1002/anie.200352998

Shah K, Tung CH, Yang K, Weissleder R, Breakefield XO

Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy Cancer Res. 2004;64(9):3236-42 - PMID: 15126365 - DOI: 10.1158/0008-5472.can-03-3516

Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS

Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res. 2004;64(12):4069-77 - PMID: 15205313 - DOI: 10.1158/0008-5472.CAN-04-1243

Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R

Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res. 2004;64(17):6247-51 - PMID: 15342411 - DOI: 10.1158/0008-5472.CAN-04-0817

Montet X, Ntziachristos V, Grimm J, Weissleder R.

Tomographic Fluorescence Mapping of Tumor Targets Cancer Res. 2005;65 (14):6330-6336 - PMID: 16024635 - DOI: 10.1158/0008-5472.CAN-05-0382

Tang Y, Kim M, Carrasco D, Kung AL, Chin L, Weissleder R.

In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging Cancer Res. 2005;65(18):8324-30 - PMID: 16166309 - DOI: 10.1158/0008-5472.CAN-05-0027

Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA Jr.

Detection of Early Antiangiogenic Effects in Human Colon Adenocarcinoma Xenografts: In vivo Changes of Tumor Blood Volume in Response to Experimental VEGFR Tyrosine Kinase Inhibitor Cancer Res. 2005;65(20):9253-60 - PMID: 16230386 - DOI: 10.1158/0008-5472.CAN-03-2619

Choi YD, Weissleder R, Tung CH.

Selective antitumor effect of novel protease-mediated photodynamic agent Cancer Res. 2006;66 (14):7225-7229 - PMID: 16849570 - DOI: 10.1158/0008-5472.CAN-06-0448

Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K.

Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo Cancer Res. 2007;67 (15):7335-7342 - PMID: 17671203 - DOI: 10.1158/0008-5472.CAN-07-0077

Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K

MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell Delivered S-TRAIL in Human Gliomas. Cancer Res. 2007;67(19):8994-9000 - PMID: 17908999 - DOI: 10.1158/0008-5472.CAN-07-1045

Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Rachamimov AS, Hochberg FH, Weissleder R, Martuza RL, Chiocca EA

Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 2007;67(19):9398-406 - PMID: 17909049 - PMCID: PMC2850558 - DOI: 10.1158/0008-5472.CAN-07-1063

Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R

Detection of early prostate cancer using a hepsin-targeted imaging agent. Cancer Res. 2008;68(7):2286-91 - PMID: 18381435 - PMCID: PMC2709884 - DOI: 10.1158/0008-5472.CAN-07-1349

Koh I, Hong R, Weissleder R, Josephson L

Sensitive NMR Sensors Detect Antibodies to Influenza. Angew Chem Int Ed Engl. 2008;47(22):4119-4121 - PMID: 18428168 - PMCID: PMC2668198 - DOI: 10.1002/anie.200800069

Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Lienard D, Lejeune F, Rimoldi D, Guillaume P, Meidenbauer N, Mackensen A, Rufer N, Lubenow N, Speiser D, Cerottini J, Romero P, Pittet M

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res. 2004;64:2865-73 - PMID: 15087405 - DOI: 10.1158/0008-5472.can-03-3066

Meidenbauer N, Zippelius A, Pittet M, Laumer M, Vogl S, Heymann J, Rehli M, Seliger B, Schwarz S, Le Gal F, Dietrich P, Andreesen R, Romero P, Mackensen A

High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res. 2004;64:6319-26 - PMID: 15342421 - DOI: 10.1158/0008-5472.CAN-04-1341

Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Lienard D, Gugerli O, Ferradini L, Robert C, Avril M, Zitvogel L, Angevin E

Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res. 2004;64:2192-8 - PMID: 15026362 - DOI: 10.1158/0008-5472.can-03-2969

Valmori D, Pittet M, Vonarbourg C, Rimoldi D, Lienard D, Speiser D, Dunbar R, Cerundolo V, Cerottini J, Romero P

Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376. Cancer Res. 1999;59:4050-5 - PMID: 10463606

Valmori D, Dutoit V, Lienard D, Rimoldi D, Pittet M, Champagne P, Ellefsen K, Sahin U, Speiser D, Lejeune F, Cerottini J, Romero P

Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients. Cancer Res. 2000;60:4499-506 - PMID: 10969798

Valmori D, Pittet M, Rimoldi D, Lienard D, Dunbar R, Cerundolo V, Lejeune F, Cerottini J, Romero P

An antigen-targeted approach to adoptive transfer therapy of cancer. Cancer Res. 1999;59:2167-73 - PMID: 10232604

Kelly K, Manos E, Jensen G, Nadauld L, Jones D

APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. Cancer Res. 2000;60:1021-7 - PMID: 10706119

Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD

Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors. Cancer Res. 2009;69(8):3472-81 - PMID: 19351838 - PMCID: PMC2785462 - DOI: 10.1158/0008-5472.CAN-08-3886

Insin N, Tracy JB, Lee H, Zimmer JP, Westervelt RM, Bawendi MG

Incorporation of iron oxide nanoparticles and quantum dots into silica microspheres. ACS Nano. 2008;2(2):197-202 - PMID: 19206619 - DOI: 10.1021/nn700344x

Fourches D, Pu D, Tassa C, Weissleder R, Shaw SY, Mumper RJ, Tropsha A

Quantitative Nanostructure-Activity Relationship Modeling. ACS Nano. 2010;4(10):5703-12 - PMID: 20857979 - PMCID: PMC2997621 - DOI: 10.1021/nn1013484

Haun J, Devaraj NK, Marinelli B, Lee H, Weissleder R

Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry. ACS Nano. 2011;5(4):3204-13 - PMID: 21351804 - PMCID: PMC3088084 - DOI: 10.1021/nn200333m

Chung H, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R

Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles. ACS Nano. 2011;5(11):8834-41 - PMID: 21967150 - PMCID: PMC3222727 - DOI: 10.1021/nn2029692

Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R

Nanoparticle Mediated Measurement of Target-Drug Binding in Cancer Cells. ACS Nano. 2011;5(11):9216-24 - PMID: 21962084 - PMCID: PMC3297118 - DOI: 10.1021/nn203450p

Wittenberg NJ, Im H, Johnson TW, Xu X, Warrington AE, Rodriguez M, Oh SH

Facile assembly of micro- and nanoarrays for sensing with natural cell membranes. ACS Nano. 2011;5(9):7555-64 - PMID: 21842844 - PMCID: PMC3183111 - DOI: 10.1021/nn202554t

Im H, Lee SH, Wittenberg NJ, Johnson TW, Lindquist NC, Nagpal P, Norris DJ, Oh SH

Template-stripped smooth Ag nanohole arrays with silica shells for surface plasmon resonance biosensing. ACS Nano. 2011;5(8):6244-53 - PMID: 21770414 - PMCID: PMC3160512 - DOI: 10.1021/nn202013v

Im H, Lindquist NC, Lesuffleur A, Oh SH

Atomic layer deposition of dielectric overlayers for enhancing the optical properties and chemical stability of plasmonic nanoholes. ACS Nano. 2010;4(2):947-54 - PMID: 20131870 - DOI: 10.1021/nn901842r

Leuschner F, Panizzi P, Chico-Calero I, Lee WW, Ueno T, Cortez-Retamozo V, Waterman P, Gorbatov R, Marinelli B, Iwamoto Y, Chudnovskiy A, Figueiredo JL, Sosnovik DE, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M

Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction. Circ Res. 2010;107(11):1364-73 - PMID: 20930148 - PMCID: PMC2992104 - DOI: 10.1161/CIRCRESAHA.110.227454

Leuschner F, Nahrendorf M

Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic. Circ Res. 2011;108(5):593-606 - PMID: 21372291 - PMCID: PMC3397211 - DOI: 10.1161/CIRCRESAHA.110.232678

Jaffer FA, Weissleder R

Seeing within: molecular imaging of the cardiovascular system Circ Res. 2004;94(4):433-45 - PMID: 15001542 - DOI: 10.1161/01.RES.0000119321.18573.5A

Kelly KA, Allport JR, Tsourkas A, Shinde-Patil VR, Josephson L, Weissleder R.

Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle Circ Res. 2005;96(3):327-36 - PMID: 15653572 - DOI: 10.1161/01.RES.0000155722.17881.dd

Nahrendorf M, Sosnovik D, Waterman P, Swirski F, Pande A, Aikawa E, Figueiredo JL, Pittet M, Weissleder R.

Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct Circ Res. 2007;100:1218-1225 - PMID: 17379832 - DOI: 10.1161/01.RES.0000265064.46075.31

Paruchuri S, Yang J, Aikawa E, Melero-Martin J, Khan Z, Loukogeorgakis S, Schoen F, Bischoff J

Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-{beta}2. Circ Res. 2006;99(8):861-9 - PMID: 16973908 - PMCID: PMC2810464 - DOI: 10.1161/01.RES.0000245188.41002.2c

Aikawa M, Rabkin E, Voglic S, Shing H, Nagai R, Schoen F, Libby P

Lipid lowering promotes accumulation of mature smooth muscle cells expressing smooth muscle myosin heavy chain isoforms in rabbit atheroma. Circ Res. 1998;83:1015-26 - PMID: 9815149 - DOI: 10.1161/01.res.83.10.1015

Taboada E, Solanas R, Rodriguez E, Weissleder R, Roig A

Supercritical-Fluid-Assisted One-Pot Synthesis of Biocompatible Core (γ-Fe2O3)/Shell(SiO2) Nanoparticles as High Relaxivity T2-Contrast Agents for Magnetic Resonance Imaging Adv Funct Mater. 2009;19 :2319-2324

Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA

Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation. J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134 - DOI: 10.1021/ja903922u

Rodriguez E, Nilges M, Weissleder R, Chen JW

Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity. J Am Chem Soc. 2010;132(1):168-77 - PMID: 19968300 - PMCID: PMC2802665 - DOI: 10.1021/ja905274f

Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG

Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots Using Tetrazine-Norbornene Cycloaddition. J Am Chem Soc. 2010;132(23):7838-9 - PMID: 20481508 - PMCID: PMC2892974 - DOI: 10.1021/ja101677r

Brueckner C, Gotz DC, Fox SP, Ryppa C, McCarthy JR, Bruhn T, Akhigbe J, Banerjee S, Daddario P, Daniell HW, Zeller M, Boyle R, Bringmann G

Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins. J Am Chem Soc. 2011;133(22):8740-8752 - PMID: 21534626 - DOI: 10.1021/ja202451t

Stahl P, Kissau L, Mazitschek R, Huwe A, Furet P, Giannis A, Waldmann H

Total synthesis and biological evaluation of the nakijiquinones. J Am Chem Soc. 2001;123(47):11586-93 - PMID: 11716712 - DOI: 10.1021/ja011413i

Chen CH, Sarkar A, Song YA, Miller MA, Kim SJ, Griffith LG, Lauffenburger DA, Han J

Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator. J Am Chem Soc. 2011;133(27):10368-71 - PMID: 21671557 - PMCID: PMC3165005 - DOI: 10.1021/ja2036628

Syeda R, Holden MA, Hwang WL, Bayley H

Screening blockers against a potassium channel with a droplet interface bilayer array. J Am Chem Soc. 2008;130(46):15543-8 - PMID: 18950170 - DOI: 10.1021/ja804968g

Hwang WL, Chen M, Cronin B, Holden MA, Bayley H

Asymmetric droplet interface bilayers. J Am Chem Soc. 2008;130(18):5878-9 - PMID: 18407631 - DOI: 10.1021/ja802089s

Hwang WL, Holden MA, White S, Bayley H

Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling. J Am Chem Soc. 2007;129(38):11854-64 - PMID: 17764183 - DOI: 10.1021/ja074071a

Perez JM, Simeone FJ, Saeki Y, Josephson L, Weissleder R

Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media J Am Chem Soc. 2003;125:10192-3 - PMID: 12926940 - DOI: 10.1021/ja036409g

Perez JM, O'Loughin T, Simeone F J, Weissleder R, Josephson L

DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents J Am Chem Soc. 2002;124:2856-7 - PMID: 11902860 - DOI: 10.1021/ja017773n

E.C. Wiener, F.P. Auteri, J.W. Chen, M.W. Brechbiel, O.A. Gansow, D.J. Schneider, R.L. Belford, R.B. Clarkson, P.C. Lauterbur

Molecular Dynamics of Ion-Chelate Complexes Attached to Starburst(TM) Dendrimers J Am Chem Soc. 1996;118:7774-7782

Hilderbrand S, Lim M, Lippard S

Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. J Am Chem Soc. 2004;126:4972-8 - PMID: 15080703 - DOI: 10.1021/ja038471j

Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U

Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheumatol. 2009;60:2314-2324 - PMID: 19644878 - PMCID: PMC3080016 - DOI: 10.1002/art.24704

Stone JH, Khosroshahi A, Hilgenberg A, Spooner A, Isselbacher EM, Stone JR

IgG4-related systemic disease and lymphoplasmacytic aortitis. Arthritis Rheumatol. 2009;60(10):3139-3145 - PMID: 19790067 - DOI: 10.1002/art.24798

Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB

Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis. Mol Cell. 2009;36(4):682-95 - PMID: 19941827 - PMCID: PMC2800995 - DOI: 10.1016/j.molcel.2009.11.002

Harisinghani MG, Weissleder R

Sensitive, noninvasive detection of lymph node metastases. PLoS Med. 2004;1(3):e66 - PMID: 15630471 - PMCID: PMC539052 - DOI: 10.1371/journal.pmed.0010066

Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R

Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma. PLoS Med. 2008;5(4):e85 - PMID: 18416599 - PMCID: PMC2292750 - DOI: 10.1371/journal.pmed.0050085

Condeelis J, Weissleder R

In Vivo Imaging in Cancer. Cold Spring Harb Perspect Biol. 2010;2(12):a003848 - PMID: 20861158 - PMCID: PMC2982169 - DOI: 10.1101/cshperspect.a003848

Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A

IKKb regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways. Nat Commun. 2011;2:318 - PMID: 21587235 - PMCID: PMC3113230 - DOI: 10.1038/ncomms1317

Shi P, Scott MA, Ghosh B, Wan D, Wissner-Gross Z, Mazitschek R, Haggarty SJ, Yanik MF

Synapse microarray identification of small molecules that enhance synaptogenesis. Nat Commun. 2011;2:510 - PMID: 22027590 - PMCID: PMC3544154 - DOI: 10.1038/ncomms1518

Ozsolak F, Goren A, Gymrek MA, Guttman M, Regev A, Bernstein BE, Milos PM

Digital transcriptome profiling from attomole-level RNA samples. Genome Res. 2010;20(4):519-25 - PMID: 20133332 - PMCID: PMC2847755 - DOI: 10.1101/gr.102129.109

Chakraverty R, Cote D, Buchli J, Cotter P, Hsu R, Zhao G, Sachs T, Pitsillides C, Bronson R, Means T, Lin CP, Sykes M

An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med. 2006;203:2021-31 - PMID: 16880259 - PMCID: PMC2118376 - DOI: 10.1084/jem.20060376

Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, Shalabi A, Shin T, Pardoll DM, Tsuchiya H

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med. 2001;193(7):839-46 - PMID: 11283156 - PMCID: PMC2193370 - DOI: 10.1084/jem.193.7.839

Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC

Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006;203(1):141-152 - PMID: 16390934 - PMCID: PMC2118091 - DOI: 10.1084/jem.20050390

Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D.

Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk J Exp Med. 2007;204:1911-1922 - PMID: 17646407 - PMCID: PMC2118664 - DOI: 10.1084/jem.20070285

Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204(12):3037-47 - PMID: 18025128 - PMCID: PMC2118517 - DOI: 10.1084/jem.20070885

Zippelius A, Pittet M, Batard P, Rufer N, de Smedt M, Guillaume P, Ellefsen K, Valmori D, Lienard D, Plum J, MacDonald H, Speiser D, Cerottini J, Romero P

Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med. 2002;195:485-94 - PMID: 11854361 - PMCID: PMC2193620 - DOI: 10.1084/jem.20011658

Dutoit V, Rubio-Godoy V, Pittet M, Zippelius A, Dietrich P, Legal F, Guillaume P, Romero P, Cerottini J, Houghten R, Pinilla C, Valmori D

Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans. J Exp Med. 2002;196:207-16 - PMID: 12119345 - PMCID: PMC2193921 - DOI: 10.1084/jem.20020242

Romero P, Dunbar P, Valmori D, Pittet M, Ogg G, Rimoldi D, Chen J, Lienard D, Cerottini J, Cerundolo V

Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes. J Exp Med. 1998;188:1641-50 - PMID: 9802976 - PMCID: PMC2212507 - DOI: 10.1084/jem.188.9.1641

Speiser D, Pittet M, Valmori D, Dunbar R, Rimoldi D, Lienard D, MacDonald H, Cerottini J, Cerundolo V, Romero P

In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes. J Exp Med. 1999;190:775-82 - PMID: 10499916 - PMCID: PMC2195637 - DOI: 10.1084/jem.190.6.775

Pittet M, Valmori D, Dunbar P, Speiser D, Lienard D, Lejeune F, Fleischhauer K, Cerundolo V, Cerottini J, Romero P

High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. J Exp Med. 1999;190:705-15 - PMID: 10477554 - PMCID: PMC2195613 - DOI: 10.1084/jem.190.5.705

Shaw SY

Molecular imaging in cardiovascular disease: targets and opportunities. Nat Rev Cardiol. 2009;6(9):569-79 - PMID: 19621013 - DOI: 10.1038/nrcardio.2009.119

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The year in molecular imaging. JACC Cardiovasc Imaging. 2010;3(11):1181-95 - PMID: 21071007 - PMCID: PMC3057415 - DOI: 10.1016/j.jcmg.2010.09.009

Pai SI, Westra WH

Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment. Annu Rev Pathol. 2009;4:49-70 - PMID: 18729723 - PMCID: PMC3703474 - DOI: 10.1146/annurev.pathol.4.110807.092158

Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ

Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. J Clin Invest. 2009;119(11):3322-8 - PMID: 19809161 - PMCID: PMC2769199 - DOI: 10.1172/JCI39939

Ueno T, Habicht A, Clarkson MR, Albin MJ, Yamaura K, Boenisch O, Popoola J, Wang Y, Yagita H, Akiba H, Ansari MJ, Yang J, Turka LA, Rothstein DM, Padera RF, Najafian N, Sayegh MH

The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest. 2008;118(2):742-51 - PMID: 18172549 - PMCID: PMC2157561 - DOI: 10.1172/JCI32451

Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M

Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice. J Clin Invest. 2010;120(7):2627-34 - PMID: 20577051 - PMCID: PMC2898607 - DOI: 10.1172/JCI42304

Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. J Clin Invest. 2010;121(1):442-5 - PMID: 21123946 - PMCID: PMC3007157 - DOI: 10.1172/JCI44339

Bouley R, Breton S, Sun T, McLaughlin M, Nsumu NN, Lin HY, Ausiello DA, Brown D

Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells. J Clin Invest. 2000;106(9):1115-26 - PMID: 11067864 - PMCID: PMC301414 - DOI: 10.1172/JCI9594

Choukroun GJ, Marshansky V, Gustafson CE, McKee M, Hajjar RJ, Rosenzweig A, Brown D, Bonventre JV

Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins. J Clin Invest. 2000;106(8):983-93 - PMID: 11032858 - PMCID: PMC314339 - DOI: 10.1172/JCI8914

Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D.

Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes J Clin Invest. 2005;115(9):2454-2461 - PMID: 16110329 - PMCID: PMC1187933 - DOI: 10.1172/JCI25048

Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ

Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata J Clin Invest. 2007;117(1):195-205 - PMID: 17200719 - PMCID: PMC1716211 - DOI: 10.1172/JCI29950

Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest. 2007;117(7):1933-1939 - PMID: 17607365 - PMCID: PMC1904317 - DOI: 10.1172/JCI31342

Ducharme A, Frantz S, Aikawa M, Rabkin E, Lindsey M, Rohde L, Schoen F, Kelly R, Werb Z, Libby P, Lee R

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest. 2000;106:55-62 - PMID: 10880048 - PMCID: PMC517910 - DOI: 10.1172/JCI8768

Laufs U, Endres M, Stagliano N, Amin-Hanjani S, Chui D, Yang S, Simoncini T, Yamada M, Rabkin E, Allen P, Huang P, Bahm M, Schoen F, Moskowitz M, Liao J

Neuroprotection mediated by changes in the endothelial actin cytoskeleton. J Clin Invest. 2000;106:15-24 - PMID: 10880044 - PMCID: PMC314365 - DOI: 10.1172/JCI9639

Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ

Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation J Clin Invest. 2008;118(12):4058-66 - PMID: 19033674 - PMCID: PMC2579705 - DOI: 10.1172/JCI36335

Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK

A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008;:ePub - PMID: 19005570 - PMCID: PMC2579884

Tung CH, Weissleder R

Arginine containing peptides as delivery vectors Adv Drug Deliv Rev. 2003;55:281-94 - PMID: 12564981 - DOI: 10.1016/s0169-409x(02)00183-7

Bogdanov AA, Lewin M, Weissleder R

Approaches and agents for imaging the vascular system Adv Drug Deliv Rev. 1999;37:279-293 - PMID: 10837740 - DOI: 10.1016/s0169-409x(98)00098-2

McCarthy JR, Weissleder R

Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev. 2008;60:1241-1251 - PMID: 18508157 - PMCID: PMC2583936 - DOI: 10.1016/j.addr.2008.03.014

McCarthy JR

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Imaging inflammation of the pancreatic islets in type 1 diabetes. Proc Natl Acad Sci U S A. 2004;101(34):12634-9 - PMID: 15304647 - PMCID: PMC515109 - DOI: 10.1073/pnas.0404307101

Ntziachristos V, Schellenberger EA, Ripoll J, Yessayan D, Graves E, Bogdanov A Jr, Josephson L, Weissleder R

Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc Natl Acad Sci U S A. 2004;101(33):12294-9 - PMID: 15304657 - PMCID: PMC514472 - DOI: 10.1073/pnas.0401137101

Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K.

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-{beta} signals in vivo Proc Natl Acad Sci U S A. 2005;102(2):419-24 - PMID: 15623559 - PMCID: PMC544311 - DOI: 10.1073/pnas.0408197102

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Use of gene expression profiling to direct in vivo molecular imaging of lung cancer Proc Natl Acad Sci U S A. 2005;102(40):14404-14409 - PMID: 16183744 - PMCID: PMC1242291 - DOI: 10.1073/pnas.0503920102

Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V.

Volumetric tomography of fluorescent proteins through small animals in vivo Proc Natl Acad Sci U S A. 2005;102:18252-18257 - PMID: 16344470 - PMCID: PMC1317905 - DOI: 10.1073/pnas.0504628102

Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA

Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006;103:5947-5952 - PMID: 16585505 - PMCID: PMC1458678 - DOI: 10.1073/pnas.0601273103

Swirski FK, Pittet MJ, Kircher MF, Aikawa E, Jaffer FA, Libby P, Weissleder R

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A. 2006;103(27):10340-5 - PMID: 16801531 - PMCID: PMC1502459 - DOI: 10.1073/pnas.0604260103

Fulci G, Breymann L,Gianni D, Kurozomi K, Rhee S, Yu J, Kaur B, Louis D, Weissleder R, Caligiuri M, Chiocca A.

Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses Proc Natl Acad Sci U S A. 2006;103:12873-12878 - PMID: 16908838 - PMCID: PMC1568940 - DOI: 10.1073/pnas.0605496103

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The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A. 2005;102(38):13616-21 - PMID: 16174750 - PMCID: PMC1224669 - DOI: 10.1073/pnas.0506769102

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In vivo imaging of T cell delivery to tumors after adoptive transfer therapy Proc Natl Acad Sci U S A. 2007;104:12457-12461 - PMID: 17640914 - PMCID: PMC1941490 - DOI: 10.1073/pnas.0704460104

Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K

Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A. 2007;104:19977-82 - PMID: 18077429 - PMCID: PMC2148408 - DOI: 10.1073/pnas.0704620104

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Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A. 2008;105:7387-7392 - PMID: 18492802 - PMCID: PMC2396702 - DOI: 10.1073/pnas.0802878105

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From oligonucleotide shapes to genomic SELEX: novel biological regulatory loops. Proc Natl Acad Sci U S A. 1997;94:59-64 - PMID: 8990161 - PMCID: PMC19236 - DOI: 10.1073/pnas.94.1.59

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Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation. Proc Natl Acad Sci U S A. 2008;105(28):9751-6 - PMID: 18607002 - PMCID: PMC2474517 - DOI: 10.1073/pnas.0710413105

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Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase Proc Natl Acad Sci U S A. 2008;105 (47):18584-18589 - PMID: 19011099 - PMCID: PMC2587593 - DOI: 10.1073/pnas.0803945105

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Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. Proc Natl Acad Sci U S A. 2008;105(49)::19126-19131 - PMID: 19015534 - PMCID: PMC2614726 - DOI: 10.1073/pnas.0804798105

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Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A. 2008;105(43):16525-30 - PMID: 18946036 - PMCID: PMC2571912 - DOI: 10.1073/pnas.0808750105

Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Bronson R, Chen J, Weissleder R, Housman D, Charest A.

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Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proc Natl Acad Sci U S A. 2009;106(8):2712-6 - PMID: 19196966 - PMCID: PMC2650331 - DOI: 10.1073/pnas.0813314106

Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci U S A. 2009;106(12):4822-7 - PMID: 19264968 - PMCID: PMC2660771 - DOI: 10.1073/pnas.0806647106

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Biosynthesis of the Caenorhabditis elegans dauer pheromone. Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283 - DOI: 10.1073/pnas.0810338106

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Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin. Proc Natl Acad Sci U S A. 2009;106(19):7786-91 - PMID: 19416890 - PMCID: PMC2683071 - DOI: 10.1073/pnas.0811750106

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Rapid detection and profiling of cancer cells in fine-needle aspirates. Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371 - DOI: 10.1073/pnas.0902365106

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Identification of genes conferring resistance to 5-fluorouracil. Proc Natl Acad Sci U S A. 2009;106(31):12938-43 - PMID: 19622726 - PMCID: PMC2722317 - DOI: 10.1073/pnas.0901451106

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Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects. Proc Natl Acad Sci U S A. 2009;106(35):14932-6 - PMID: 19706423 - PMCID: PMC2736449 - DOI: 10.1073/pnas.0902408106

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Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy. Proc Natl Acad Sci U S A. 2005;102:16807-12 - PMID: 16263923 - PMCID: PMC1283840 - DOI: 10.1073/pnas.0508282102

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Sickle cell vasoocclusion and rescue in a microfluidic device. Proc Natl Acad Sci U S A. 2007;104(51):20496-500 - PMID: 18077341 - PMCID: PMC2154459 - DOI: 10.1073/pnas.0707122105

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Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc Natl Acad Sci U S A. 2010;107(4):1565-70 - PMID: 20080688 - PMCID: PMC2824379 - DOI: 10.1073/pnas.0908682107

Tsigkou O, Pomerantseva I, Spencer JA, Redondo PA, Hart AR, O'Doherty E, Lin Y, Friedrich CC, Daheron L, Lin CP, Sundback CA, Vacanti JP, Neville C

Regenerative Medicine Special Feature: Engineered vascularized bone grafts. Proc Natl Acad Sci U S A. 2010;107(8):3311-6 - PMID: 20133604 - PMCID: PMC2840421 - DOI: 10.1073/pnas.0905445107

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Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proc Natl Acad Sci U S A. 2010;107(11):5124-9 - PMID: 20194748 - PMCID: PMC2841922 - DOI: 10.1073/pnas.0911929107

Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R

Hybrid PET-optical imaging using targeted probes Proc Natl Acad Sci U S A. 2010;107(17):7910-5 - PMID: 20385821 - PMCID: PMC2867879 - DOI: 10.1073/pnas.0915163107

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Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease. Proc Natl Acad Sci U S A. 2010;107(28):12617-22 - PMID: 20616024 - PMCID: PMC2906581 - DOI: 10.1073/pnas.1006774107

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Gao X, Eladari D, Leviel F, Tew BY, Miro-Julia

Deletion of hensin/DMBT1 blocks conversion of {beta}- to {alpha}-intercalated cells and induces distal renal tubular acidosis. Proc Natl Acad Sci U S A. 2010;107(50):21872-7 - PMID: 21098262 - PMCID: PMC3003085 - DOI: 10.1073/pnas.1010364107

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Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A. 2010;108(2):492-7 - PMID: 21183721 - PMCID: PMC3021060 - DOI: 10.1073/pnas.1016789108

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Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. Proc Natl Acad Sci U S A. 2011;108(36):14908-13 - PMID: 21737748 - PMCID: PMC3169118 - DOI: 10.1073/pnas.1109023108

Zhao B, Zou J, Wang H, Johannsen E, Peng CW, Quackenbush J, Mar JC, Morton CC, Freedman ML, Blacklow SC, Aster JC, Bernstein BE, Kieff E

Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth. Proc Natl Acad Sci U S A. 2011;108(36):14902-7 - PMID: 21746931 - PMCID: PMC3169132 - DOI: 10.1073/pnas.1108892108

Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R

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Kleijn A*, Chen JW*, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G

Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clin Cancer Res. 2011;17(13):4484-93 - PMID: 21558403 - PMCID: PMC3131449 - DOI: 10.1158/1078-0432.CCR-11-0575

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Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor. Clin Cancer Res. 2008;14(22):7340-7 - PMID: 19010849 - PMCID: PMC2744414 - DOI: 10.1158/1078-0432.CCR-08-0642

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Kelloff GJ, Krohn KA, Larson SM, Weissleder R, Mankoff DA, Hoffman JM, Link JM, Guyton KZ, Eckelman WC, Scher HI, O

The progress and promise of molecular imaging probes in oncologic drug development. Clin Cancer Res. 2005;11(22):7967-85 - PMID: 16299226 - DOI: 10.1158/1078-0432.CCR-05-1302

Ayyoub M, Zippelius A, Pittet M, Rimoldi D, Valmori D, Cerottini J, Romero P, Lejeune F, Lienard D, Speiser D

Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1. Clin Cancer Res. 2003;9:669-77 - PMID: 12576434

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Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK

Regression of drug-resistant lung cancer by the combination of rosiglitazone and Carboplatin. Clin Cancer Res. 2008;14(20):6478-86 - PMID: 18927287 - PMCID: PMC2696122 - DOI: 10.1158/1078-0432.CCR-08-1128

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Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev. 2002;188:81-96 - PMID: 12445283 - DOI: 10.1034/j.1600-065x.2002.18808.x

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Polymeric Nanoparticle Preparation that Eradicates Tumors. Nano Lett. 2005;5:2552-6 - PMID: 16351214 - DOI: 10.1021/nl0519229

Quinti L, Weissleder R, Tung CH

A Fluorescent Nanosensor for Apoptotic Cells Nano Lett. 2006;6 (3):488-490 - PMID: 16522048 - DOI: 10.1021/nl0524694

Lee H, Purdon AM, Chu V, Westervelt RM

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Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg F, Weissleder R, Carson W, Chiocca A, Kaur B.

Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy J Natl Cancer Inst. 2007;(99) 23:1768-1781 - PMID: 18042934 - DOI: 10.1093/jnci/djm229

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Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression Ann Neurol. 2005;57(1):34-41 - PMID: 15622535 - DOI: 10.1002/ana.20306

Johnson J, Wiley R, Fattouh R, Swirski F, Gajewska B, Coyle A, Gutierrez-Ramos J, Ellis R, Inman M, Jordana M

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am J Resp Crit Care. 2004;169(3):378-85 - PMID: 14597485 - DOI: 10.1164/rccm.200308-1094OC

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Creatine kinase knockout mice show left ventricular hypertrophy and dilatation, but unaltered remodeling post-myocardial infarction. Cardiovasc Res. 2005;65(2):419-27 - PMID: 15639481 - DOI: 10.1016/j.cardiores.2004.10.006

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The estrogen receptor-alpha agonist 16alpha-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats. Cardiovasc Res. 2005;67(4):604-12 - PMID: 15950203 - DOI: 10.1016/j.cardiores.2005.04.035

Hu K, Gaudron P, Anders HJ, Weidemann F, Turschner O, Nahrendorf M, Ertl G

Chronic effects of early started angiotensin converting enzyme inhibition and angiotensin AT1-receptor subtype blockade in rats with myocardial infarction: role of bradykinin. Cardiovasc Res. 1998;39(2):401-12 - PMID: 9798525 - DOI: 10.1016/s0008-6363(98)00090-x

Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ

Implantable diagnostic device for cancer monitoring. Biosens Bioelectron. 2009;24(11):3252-7 - PMID: 19442510 - PMCID: PMC2738970 - DOI: 10.1016/j.bios.2009.04.010

Kim DE, Kim JY, Nahrendorf M, Lee SK, Ryu JH, Kim K, Kwon IC, Schellingerhout D

Direct Thrombus Imaging as a Means to Control the Variability of Mouse Embolic Infarct Models: The Role of Optical Molecular Imaging. Stroke. 2011;42(12):3566-73 - PMID: 22020025 - DOI: 10.1161/STROKEAHA.111.629428

Zaharchuk G, Mandeville JB, Bogdanov AA Jr, Weissleder R, Rosen BR, Marota JJ

Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension Stroke. 1999;30:2197-204; discussion 2204-5 - PMID: 10512929 - DOI: 10.1161/01.str.30.10.2197

Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R

Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine Model Stroke. 2004;35:952-7 - PMID: 14988578 - DOI: 10.1161/01.STR.0000120308.21946.5D

Touhami M, Fauvel-Lafève F, Da Silva N, Chomienne C, Legrand C

Induction of thrombospondin-1 by all-trans retinoic acid modulates growth and differentiation of HL-60 myeloid leukemia cells. Leukemia. 1997;11(12):2137-42 - PMID: 9447832 - DOI: 10.1038/sj.leu.2400866

Gruss HJ, DaSilva N, Hu ZB, Uphoff CC, Goodwin RG, Drexler HG

Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines. Leukemia. 1994;8(12):2083-94 - PMID: 7528856

DaSilva N, Hu ZB, Ma W, Rosnet O, Birnbaum D, Drexler HG

Expression of the FLT3 gene in human leukemia-lymphoma cell lines. Leukemia. 1994;8(5):885-8 - PMID: 8182945

Naxerova K, Bult CJ, Peaston A, Fancher K, Knowles BB, Kasif S, Kohane IS

Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers. Genome Biol. 2008;9(7):R108 - PMID: 18611264 - PMCID: PMC2530866 - DOI: 10.1186/gb-2008-9-7-r108

Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R

Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis. Brain. 2008;131(Pt 4):1123-33 - PMID: 18234693 - PMCID: PMC4044727 - DOI: 10.1093/brain/awn004

Ladapo JA, Jaffer FA, Weinstein MC, Froelicher ES

Projected Cost-effectiveness of Smoking Cessation Interventions in Patients Hospitalized With Myocardial Infarction. Arch Intern Med. 2011;171(1):39-45 - PMID: 21220659 - DOI: 10.1001/archinternmed.2010.479

Bogdanov A, Weissleder R

The development of in vivo imaging systems to study gene expression. Trends Biotechnol. 1998;16(1):5-10 - PMID: 9470227 - DOI: 10.1016/S0167-7799(97)01150-5

Zhao M, Weissleder R

Intracellular cargo delivery using tat peptide and derivatives Med Res Rev. 2004;24:1-12 - PMID: 14595670 - DOI: 10.1002/med.10056

Pittet M, Zippelius A, Valmori D, Speiser D, Cerottini J, Romero P

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor. Trends Immunol. 2002;23:325-8 - PMID: 12103339 - DOI: 10.1016/s1471-4906(02)02244-5

Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bunemann M

Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends Pharmacol Sci. 2008;29(3):159-65 - PMID: 18262662 - DOI: 10.1016/j.tips.2007.12.002

Libby P, DiCarli M, Weissleder R

The Vascular Biology of Atherosclerosis and Imaging Targets. J Nucl Med. 2010;51 Suppl 1:33S-37S - PMID: 20395349 - DOI: 10.2967/jnumed.109.069633

Kramer CM, Sinusas AJ, Sosnovik DE, French BA, Bengel FM

Multimodality Imaging of Myocardial Injury and Remodeling. J Nucl Med. 2010;51 Suppl 1:107S-121S - PMID: 20395347 - PMCID: PMC3078824 - DOI: 10.2967/jnumed.109.068221

Bogdanov AA, Callahan RJ, Wilkinson RA, Martin C, Cameron JA, Fischman AJ, Brady TJ, Weissleder R

Synthetic copolymer kit for radionuclide blood-pool imaging. J Nucl Med. 1994;35(11):1880-6 - PMID: 7965173

Izawa A*, Ueno T*, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R

Importance of donor- and recipient-derived selectins in cardiac allograft rejection. J Am Soc Nephrol. 2007;18(11):2929-36 - PMID: 17928506 - DOI: 10.1681/ASN.2006111261

Ueno T, Tanaka K, Jurewicz M, Murayama T, Guleria I, Fiorina P, Paez JC, Augello A, Vergani A, Wong M, Smith RN, Abdi R

Divergent role of donor dendritic cells in rejection versus tolerance of allografts. J Am Soc Nephrol. 2009;20(3):535-44 - PMID: 19129312 - PMCID: PMC2653678 - DOI: 10.1681/ASN.2008040377

Xia Y, Babitt JL, Bouley R, Zhang Y, Silva ND, Chen S, Zhuang Z, Samad TA, Brenner GJ, Anderson JL, Hong CC, Schneyer AL, Brown D, Lin HY

Dragon Enhances BMP Signaling and Increases Transepithelial Resistance in Kidney Epithelial Cells. J Am Soc Nephrol. 2010;21(4):666-77 - PMID: 20167703 - PMCID: PMC2844302 - DOI: 10.1681/ASN.2009050511

Bouley R, Lu HA, Nunes P, Da Silva N, McLaughlin M, Chen Y, Brown D

Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration. J Am Soc Nephrol. 2010;22(1):59-72 - PMID: 21071524 - PMCID: PMC3014035 - DOI: 10.1681/ASN.2009121267

Breton S, Marsolais M, Lapointe JY, Laprade R

Cell volume increases of physiologic amplitude activate basolateral K and CI conductances in the rabbit proximal convoluted tubule. J Am Soc Nephrol. 1996;7(10):2072-87 - PMID: 8915967 - DOI: 10.1681/ASN.V7102072

Breton S, Brown D

Cold-induced microtubule disruption and relocalization of membrane proteins in kidney epithelial cells. J Am Soc Nephrol. 1998;9(2):155-66 - PMID: 9527391 - DOI: 10.1681/ASN.V92155

Sabolić I, Herak-Kramberger CM, Breton S, Brown D

Na/K-ATPase in intercalated cells along the rat nephron revealed by antigen retrieval. J Am Soc Nephrol. 1999;10(5):913-22 - PMID: 10232676 - DOI: 10.1681/ASN.V105913

Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Desch

Pendrin regulation in mouse kidney primarily is chloride-dependent. J Am Soc Nephrol. 2006;17(8):2153-63 - PMID: 16825334 - DOI: 10.1681/ASN.2005101054

Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D

Impaired Tubular Uptake Explains Albuminuria in Early Diabetic Nephropathy. J Am Soc Nephrol. 2008;20(3):489-94 - PMID: 19118149 - PMCID: PMC2653682 - DOI: 10.1681/ASN.2008050503

Corradini E, Babitt JL, Lin HY

The RGM/DRAGON family of BMP co-receptors. Cytokine Growth Factor Rev. 2009;20(5-6):389-98 - PMID: 19897400 - PMCID: PMC3715994 - DOI: 10.1016/j.cytogfr.2009.10.008

Hilderbrand SA, Weissleder R

Near-infrared fluorescence: application to in vivo molecular imaging. Curr Opin Chem Biol. 2009;14:1-9 - PMID: 19879798 - DOI: 10.1016/j.cbpa.2009.09.029

Ku M, Koche R, Rheinbay E, Mendenhall E, Endoh M, Mikkelsen T, Presser A, Nusbaum C, Xie X, Chi A, Adli M, Kasif S, Ptaszek L, Cowan C, Lander E, Koseki H, Bernstein B

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet. 2008;4(10):e1000242 - PMID: 18974828 - PMCID: PMC2567431 - DOI: 10.1371/journal.pgen.1000242

Mendenhall EM, Koche RP, Truong T, Zhou VW, Issac B, Chi AS, Ku M, Bernstein BE

GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells. PLoS Genet. 2010;6(12):e1001244 - PMID: 21170310 - PMCID: PMC3000368 - DOI: 10.1371/journal.pgen.1001244

Ziller MJ, Müller F, Liao J, Zhang Y, Gu H, Bock C, Boyle P, Epstein CB, Bernstein BE, Lengauer T, Gnirke A, Meissner A

Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types. PLoS Genet. 2011;7(12):e1002389 - PMID: 22174693 - PMCID: PMC3234221 - DOI: 10.1371/journal.pgen.1002389

Choy E, Yelensky R, Bonakdar S, Plenge RM, Saxena R, De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C, Rivas M, Dermitzakis ET, Cahir-McFarland E, Kieff E, Hafler D, Daly MJ, Altshuler D

Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines PLoS Genet. 2008;4(11):e1000287 - PMID: 19043577 - PMCID: PMC2583954 - DOI: 10.1371/journal.pgen.1000287

Shtatland T, Gill S, Javornik B, Johansson H, Singer B, Uhlenbeck O, Zichi D, Gold L

Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. Nucleic Acids Res. 2000;28:E93 - PMID: 11058143 - PMCID: PMC113162 - DOI: 10.1093/nar/28.21.e93

Singer B, Shtatland T, Brown D, Gold L

Libraries for genomic SELEX. Nucleic Acids Res. 1997;25:781-6 - PMID: 9016629 - PMCID: PMC146522 - DOI: 10.1093/nar/25.4.781

Abrams E, Shtatland T, Lerman L

PCR assay for a polymorphic TaqI site in the human K-ras-2 gene on chromosome 12p (KRAS2). Nucleic Acids Res. 1991;19:4795 - PMID: 1679926 - PMCID: PMC328755 - DOI: 10.1093/nar/19.17.4795

Babitt JL, Lin HY

The molecular pathogenesis of hereditary hemochromatosis. Semin Liver Dis. 2011;31(3):280-92 - PMID: 21901658 - DOI: 10.1055/s-0031-1286059

Lo Celso C, Lin CP, Scadden DT

In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow. Nat Protoc. 2010;6(1):1-14 - PMID: 21212779 - PMCID: PMC3382040 - DOI: 10.1038/nprot.2010.168

Adli M, Bernstein BE

Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq. Nat Protoc. 2011;6(10):1656-68 - PMID: 21959244 - PMCID: PMC4493313 - DOI: 10.1038/nprot.2011.402

Pittet M, Swirski F, Reynolds F, Josephson L, Weissleder R.

Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles Nat Protoc. 2006;1(1):73-79 - PMID: 17406214 - DOI: 10.1038/nprot.2006.11

Bremer C, Mustafa M, Bogdanov A Jr, Ntziachristos V, Petrovsky A, Weissleder R

Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice Radiology. 2003;226:214-20 - PMID: 12511693 - DOI: 10.1148/radiol.2261012140

Mahmood U, Tung CH, Tang Y, Weissleder R

Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice Radiology. 2002;224:446-51 - PMID: 12147841 - DOI: 10.1148/radiol.2242011589

Bremer C, Tung CH, Bogdanov A Jr, Weissleder R

Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes Radiology. 2002;222:814-8 - PMID: 11867806 - DOI: 10.1148/radiol.2223010812

Weissleder R, Mahmood U

Molecular imaging Radiology. 2001;219:316-33 - PMID: 11323453 - DOI: 10.1148/radiology.219.2.r01ma19316

Moore A, Josephson L, Bhorade RM, Basilion JP, Weissleder R

Human transferrin receptor gene as a marker gene for MR imaging Radiology. 2001;221:244-50 - PMID: 11568347 - DOI: 10.1148/radiol.2211001784

Bremer C, Bredow S, Mahmood U, Weissleder R, Tung CH

Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model Radiology. 2001;221:523-9 - PMID: 11687699 - DOI: 10.1148/radiol.2212010368

Moore A, Marecos E, Bogdanov A Jr, Weissleder R

Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model Radiology. 2000;214:568-74 - PMID: 10671613 - DOI: 10.1148/radiology.214.2.r00fe19568

Weissleder R

Molecular imaging: exploring the next frontier Radiology. 1999;212:609-14 - PMID: 10478223 - DOI: 10.1148/radiology.212.3.r99se18609

Mahmood U, Tung CH, Bogdanov A Jr, Weissleder R

Near-infrared optical imaging of protease activity for tumor detection Radiology. 1999;213:866-70 - PMID: 10580968 - DOI: 10.1148/radiology.213.3.r99dc14866

Funovics MA, Weissleder R, Mahmood U

Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 2004;231(3):659-66 - PMID: 15163807 - DOI: 10.1148/radiol.2313030831

Mahmood U

Can MR Imaging Be Used to Track Delivery of Intravascularly Administered Stem Cells? Radiology. 2004;233(3):625-6 - PMID: 15564396 - DOI: 10.1148/radiol.2333041190

Chen JW, Querol Sans M, Bogdanov Jr A, Weissleder R

Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates Radiology. 2006;240 (2):473-81 - PMID: 16864673 - DOI: 10.1148/radiol.2402050994

Mahmood U

Can a clinically used chemoembolization vehicle improve transgene delivery? Radiology. 2006;240(3):619-20 - PMID: 16926318 - DOI: 10.1148/radiol.2403060761

Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D

Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by using Real-time Bioluminescent Imaging. Radiology. 2006;241(3):822-830 - PMID: 17114629 - DOI: 10.1148/radiol.2413050466

Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R.

Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007;242 (3):751-758 - PMID: 17325064 - DOI: 10.1148/radiol.2423052065

Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U

Colonic Adenocarcinomas: Near-Infrared Microcatheter Imaging of Smart Probes for Early Detection. Radiology. 2007;244(1):232-8 - PMID: 17507718 - DOI: 10.1148/radiol.2441052114

Upadhyay R, Sheth RA, Weissleder R, Mahmood U

Quantitative Real-time Catheter-based Fluorescence Molecular Imaging in Mice. Radiology. 2007;245(2):523-31 - PMID: 17940307 - DOI: 10.1148/radiol.2452061613

Nahrendorf M, Hiller K, Theisen D, Hu K, Waller C, Kaiser R, Haase A, Ertl G, Brinkmann R, Bauer W

Effect of transmyocardial laser revascularization on myocardial perfusion and left ventricular remodeling after myocardial infarction in rats. Radiology. 2002;225(2):487-93 - PMID: 12409584 - DOI: 10.1148/radiol.2252011325

Goldberg M, Gazelle G, Boland G, Hahn P, Mayo-Smith W, Pivovarov M, Halpern E, Wittenberg J

Focal hepatic lesions: effect of three-dimensional wavelet compression on detection at CT. Radiology. 1997;202:159-65 - PMID: 8988206 - DOI: 10.1148/radiology.202.1.8988206

Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U

Human Breast Cancer Tumor Models: Molecular Imaging of Drug Susceptibility and Dosing during HER2/neu-targeted Therapy. Radiology. 2008;248(3):925-35 - PMID: 18647846 - PMCID: PMC2798096 - DOI: 10.1148/radiol.2482071496

Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schar M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M

Off-Resonance Angiography: A New Method to Depict Vessels--Phantom and Rabbit Studies. Radiology. 2008;249(2)::501-509 - PMID: 18780823 - PMCID: PMC2657865 - DOI: 10.1148/radiol.2491071706

Sosnovik DE

Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques? Radiology. 2009;251:309-10 - PMID: 19401565 - DOI: 10.1148/radiol.2512090268

Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U

Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation. Radiology. 2009;251(3):813-21 - PMID: 19474377 - PMCID: PMC2687531 - DOI: 10.1148/radiol.2513081450

Pandharipande PV, Gervais DA, Hartman RI, Harisinghani MG, Feldman AS, Mueller PR, Gazelle GS

Renal Mass Biopsy to Guide Treatment Decisions for Small Incidental Renal Tumors: A Cost-effectiveness Analysis. Radiology. 2010;256(3):836-46 - PMID: 20720070 - PMCID: PMC2923731 - DOI: 10.1148/radiol.10092013

de Marco G, Bogdanov A, Marecos E, Moore A, Simonova M, Weissleder R

MR imaging of gene delivery to the central nervous system with an artificial vector. Radiology. 1998;208(1):65-71 - PMID: 9646794 - DOI: 10.1148/radiology.208.1.9646794

Weissleder R, Simonova M, Bogdanova A, Bredow S, Enochs WS, Bogdanov A

MR imaging and scintigraphy of gene expression through melanin induction. Radiology. 1997;204(2):425-9 - PMID: 9240530 - DOI: 10.1148/radiology.204.2.9240530

Enochs WS, Petherick P, Bogdanova A, Mohr U, Weissleder R

Paramagnetic metal scavenging by melanin: MR imaging. Radiology. 1997;204(2):417-23 - PMID: 9240529 - DOI: 10.1148/radiology.204.2.9240529

Harisinghani MG, Saini S, Weissleder R, Halpern EF, Schima W, Rubin DL, Stillman AE, Sica GT, Small WC, Hahn PF

Differentiation of liver hemangiomas from metastases and hepatocellular carcinoma at MR imaging enhanced with blood-pool contrast agent Code-7227. Radiology. 1997;202(3):687-91 - PMID: 9051017 - DOI: 10.1148/radiology.202.3.9051017

Harika L, Weissleder R, Poss K, Papisov MI

Macromolecular intravenous contrast agent for MR lymphography: characterization and efficacy studies. Radiology. 1996;198(2):365-70 - PMID: 8596833 - DOI: 10.1148/radiology.198.2.8596833

Gupta H, Wilkinson RA, Bogdanov AA, Callahan RJ, Weissleder R

Inflammation: imaging with methoxy poly(ethylene glycol)-poly-L-lysine-DTPA, a long-circulating graft copolymer. Radiology. 1995;197(3):665-9 - PMID: 7480736 - DOI: 10.1148/radiology.197.3.7480736

Zimmer C, Weissleder R, Poss K, Bogdanova A, Wright SC, Enochs WS

MR imaging of phagocytosis in experimental gliomas. Radiology. 1995;197(2):533-8 - PMID: 7480707 - DOI: 10.1148/radiology.197.2.7480707

Zimmer C, Weissleder R, O'Connor D, LaPointe L, Brady TJ, Enochs WS

Cerebral iron oxide distribution: in vivo mapping with MR imaging. Radiology. 1995;196(2):521-7 - PMID: 7617871 - DOI: 10.1148/radiology.196.2.7617871

Gupta H, Weissleder R, Bogdanov AA, Brady TJ

Experimental gastrointestinal hemorrhage: detection with contrast-enhanced MR imaging and scintigraphy. Radiology. 1995;196(1):239-44 - PMID: 7784574 - DOI: 10.1148/radiology.196.1.7784574

Weissleder R

Liver MR imaging with iron oxides: toward consensus and clinical practice. Radiology. 1994;193(3):593-5 - PMID: 7972790 - DOI: 10.1148/radiology.193.3.7972790

Reimer P, Weissleder R, Shen T, Knoefel WT, Brady TJ

Pancreatic receptors: initial feasibility studies with a targeted contrast agent for MR imaging. Radiology. 1994;193(2):527-31 - PMID: 7972773 - DOI: 10.1148/radiology.193.2.7972773

van Everdingen KJ, Enochs WS, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R

Determinants of in vivo MR imaging of slow axonal transport. Radiology. 1994;193(2):485-91 - PMID: 7526413 - DOI: 10.1148/radiology.193.2.7526413

Weissleder R, Heautot JF, Schaffer BK, Nossiff N, Papisov MI, Bogdanov A, Brady TJ

MR lymphography: study of a high-efficiency lymphotrophic agent. Radiology. 1994;191(1):225-30 - PMID: 8134576 - DOI: 10.1148/radiology.191.1.8134576

Bogdanov AA, Weissleder R, Frank HW, Bogdanova AV, Nossif N, Schaffer BK, Tsai E, Papisov MI, Brady TJ

A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology. 1993;187(3):701-6 - PMID: 8497616 - DOI: 10.1148/radiology.187.3.8497616

Reimer P, Weissleder R, Wittenberg J, Brady TJ

Receptor-directed contrast agents for MR imaging: preclinical evaluation with affinity assays. Radiology. 1992;182(2):565-9 - PMID: 1732982 - DOI: 10.1148/radiology.182.2.1732982

Weissleder R, Lee AS, Khaw BA, Shen T, Brady TJ

Antimyosin-labeled monocrystalline iron oxide allows detection of myocardial infarct: MR antibody imaging. Radiology. 1992;182(2):381-5 - PMID: 1732953 - DOI: 10.1148/radiology.182.2.1732953

Weissleder R, Lee AS, Fischman AJ, Reimer P, Shen T, Wilkinson R, Callahan RJ, Brady TJ

Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging. Radiology. 1991;181(1):245-9 - PMID: 1887040 - DOI: 10.1148/radiology.181.1.1887040

Reimer P, Weissleder R, Brady TJ, Yeager AE, Baldwin BH, Tennant BC, Wittenberg J

Experimental hepatocellular carcinoma: MR receptor imaging. Radiology. 1991;180(3):641-5 - PMID: 1871273 - DOI: 10.1148/radiology.180.3.1871273

Seneterre E, Weissleder R, Jaramillo D, Reimer P, Lee AS, Brady TJ, Wittenberg J

Bone marrow: ultrasmall superparamagnetic iron oxide for MR imaging. Radiology. 1991;179(2):529-33 - PMID: 2014305 - DOI: 10.1148/radiology.179.2.2014305

Reimer P, Weissleder R, Lee AS, Buettner S, Wittenberg J, Brady TJ

Asialoglycoprotein receptor function in benign liver disease: evaluation with MR imaging. Radiology. 1991;178(3):769-74 - PMID: 1994416 - DOI: 10.1148/radiology.178.3.1994416

Lee AS, Weissleder R, Brady TJ, Wittenberg J

Lymph nodes: microstructural anatomy at MR imaging. Radiology. 1991;178(2):519-22 - PMID: 1987619 - DOI: 10.1148/radiology.178.2.1987619

Reimer P, Weissleder R, Lee AS, Wittenberg J, Brady TJ

Receptor imaging: application to MR imaging of liver cancer. Radiology. 1990;177(3):729-34 - PMID: 2243978 - DOI: 10.1148/radiology.177.3.2243978

Hahn PF, Stark DD, Lewis JM, Saini S, Elizondo G, Weissleder R, Fretz CJ, Ferrucci JT

First clinical trial of a new superparamagnetic iron oxide for use as an oral gastrointestinal contrast agent in MR imaging. Radiology. 1990;175(3):695-700 - PMID: 2343116 - DOI: 10.1148/radiology.175.3.2343116

Weissleder R, Elizondo G, Wittenberg J, Lee AS, Josephson L, Brady TJ

Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology. 1990;175(2):494-8 - PMID: 2326475 - DOI: 10.1148/radiology.175.2.2326475

Weissleder R, Elizondo G, Wittenberg J, Rabito CA, Bengele HH, Josephson L

Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging. Radiology. 1990;175(2):489-93 - PMID: 2326474 - DOI: 10.1148/radiology.175.2.2326474

Elizondo G, Weissleder R, Stark DD, Guerra J, Garza J, Fretz CJ, Todd LE, Ferrucci JT

Hepatic cirrhosis and hepatitis: MR imaging enhanced with superparamagnetic iron oxide. Radiology. 1990;174(3 Pt 1):797-801 - PMID: 2305063 - DOI: 10.1148/radiology.174.3.2305063

Hahn PF, Stark DD, Weissleder R, Elizondo G, Saini S, Ferrucci JT

Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology. 1990;174(2):361-6 - PMID: 2296646 - DOI: 10.1148/radiology.174.2.2296646

Fretz CJ, Elizondo G, Weissleder R, Hahn PF, Stark DD, Ferrucci JT

Superparamagnetic iron oxide-enhanced MR imaging: pulse sequence optimization for detection of liver cancer. Radiology. 1989;172(2):393-7 - PMID: 2748820 - DOI: 10.1148/radiology.172.2.2748820

Weissleder R, Thrall JH

The lymphatic system: diagnostic imaging studies. Radiology. 1989;172(2):315-7 - PMID: 2748809 - DOI: 10.1148/radiology.172.2.2748809

Weissleder R, Elizondo G, Josephson L, Compton CC, Fretz CJ, Stark DD, Ferrucci JT

Experimental lymph node metastases: enhanced detection with MR lymphography. Radiology. 1989;171(3):835-9 - PMID: 2717761 - DOI: 10.1148/radiology.171.3.2717761

Dousset M, Weissleder R, Hendrick RE, Stark DD, Fretz CJ, Elizondo G, Hahn PF, Saini S, Ferrucci JT

Short TI inversion-recovery imaging of the liver: pulse-sequence optimization and comparison with spin-echo imaging. Radiology. 1989;171(2):327-33 - PMID: 2704797 - DOI: 10.1148/radiology.171.2.2704797

Rummeny E, Weissleder R, Sironi S, Stark DD, Comptom CC, Hahn PF, Saini S, Wittenberg J, Ferrucci JT

Central scars in primary liver tumors: MR features, specificity, and pathologic correlation. Radiology. 1989;171(2):323-6 - PMID: 2539605 - DOI: 10.1148/radiology.171.2.2539605

Weissleder H, Weissleder R

Interstitial lymphangiography: initial clinical experience with a dimeric nonionic contrast agent. Radiology. 1989;170(2):371-4 - PMID: 2911660 - DOI: 10.1148/radiology.170.2.2911660

Weissleder R, Hahn PF, Stark DD, Elizondo G, Saini S, Todd LE, Wittenberg J, Ferrucci JT

Superparamagnetic iron oxide: enhanced detection of focal splenic tumors with MR imaging. Radiology. 1988;169(2):399-403 - PMID: 3174987 - DOI: 10.1148/radiology.169.2.3174987

Stark DD, Weissleder R, Elizondo G, Hahn PF, Saini S, Todd LE, Wittenberg J, Ferrucci JT

Superparamagnetic iron oxide: clinical application as a contrast agent for MR imaging of the liver. Radiology. 1988;168(2):297-301 - PMID: 3393649 - DOI: 10.1148/radiology.168.2.3393649

Weissleder H, Weissleder R

Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology. 1988;167(3):729-35 - PMID: 3363131 - DOI: 10.1148/radiology.167.3.3363131

Tsang YM, Stark DD, Chen MC, Weissleder R, Wittenberg J, Ferrucci JT

Hepatic micrometastases in the rat: ferrite-enhanced MR imaging. Radiology. 1988;167(1):21-4 - PMID: 3347724 - DOI: 10.1148/radiology.167.1.3347724

Weissleder R, Stark DD, Rummeny EJ, Compton CC, Ferrucci JT

Splenic lymphoma: ferrite-enhanced MR imaging in rats. Radiology. 1988;166(2):423-30 - PMID: 3336717 - DOI: 10.1148/radiology.166.2.3336717

Elizondo G, Weissleder R, Stark DD, Todd LE, Compton C, Wittenberg J, Ferrucci JT

Amebic liver abscess: diagnosis and treatment evaluation with MR imaging. Radiology. 1987;165(3):795-800 - PMID: 2891154 - DOI: 10.1148/radiology.165.3.2891154

Waller C, Kahler E, Hiller KH, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer WR

Myocardial perfusion and intracapillary blood volume in rats at rest and with coronary dilatation: MR imaging in vivo with use of a spin-labeling technique. Radiology. 2000;215(1):189-97 - PMID: 10751486 - DOI: 10.1148/radiology.215.1.r00ap07189

Nahrendorf M, Sosnovik DE

Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging? Radiology. 2011;260(2):309-10 - PMID: 21778448 - DOI: 10.1148/radiol.11111017

Su HS, Nahrendorf M, Panizzi PR, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW

Vasculitis: Molecular Imaging by Targeting the Inflammatory Enzyme Myeloperoxidase. Radiology. 2011;262(1):181-90 - PMID: 22084204 - PMCID: PMC3244672 - DOI: 10.1148/radiol.11110040

Miranda KC, Bond DT, McKee M, Skog J, Paunescu TG, Da Silva N, Brown D, Russo LM

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease. Kidney Int. 2010;78(2):191-9 - PMID: 20428099 - PMCID: PMC4451567 - DOI: 10.1038/ki.2010.106

Schreiner R, Frindt G, Diaz F, Carvajal-Gonzalez JM, Perez Bay AE, Palmer LG, Marshansky V, Brown D, Philp NJ, Rodriguez-Boulan E

The absence of a clathrin adapter confers unique polarity essential to proximal tubule function. Kidney Int. 2010;78(4):382-8 - PMID: 20531453 - PMCID: PMC3684398 - DOI: 10.1038/ki.2010.166

Brown D, Breton S

Sorting proteins to their target membranes. Kidney Int. 2000;57(3):816-24 - PMID: 10720934 - DOI: 10.1046/j.1523-1755.2000.00920.x

Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD

The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int. 2007;71(6):504-13 - PMID: 17228368 - DOI: 10.1038/sj.ki.5002041

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Controversies in nephrology: Response to ''renal albumin handling, facts, and artifacts'' Kidney Int. 2007;72(10):1195-7 - PMID: 17851467 - DOI: 10.1038/sj.ki.5002528

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Response to ''Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique'' Kidney Int. 2007;72:1411 - PMID: 18004315

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Response to ''On the origin of albuminuria'' Kidney Int. 2007;72:1409-10 - PMID: 18004312

Gutierrez O, Lin H

Refractory hyponatremia. Kidney Int. 2007;71(1):79-82 - PMID: 16985516 - DOI: 10.1038/sj.ki.5001845

Zalyapin EA, Bouley R, Hasler U, Vilardaga JP, Lin HY, Brown D, Ausiello DA

Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling. Kidney Int. 2008;74(12):1557-67 - PMID: 18813286 - PMCID: PMC3730289 - DOI: 10.1038/ki.2008.412

Miller RL, Lucero OM, Riemondy KA, Baumgartner BK, Brown D, Breton S, Nelson RD

The V-ATPase B1-subunit promoter drives expression of Cre recombinase in intercalated cells of the kidney. Kidney Int. 2008;75(4):435-9 - PMID: 19052537 - PMCID: PMC4301582 - DOI: 10.1038/ki.2008.569

Moore A, Bonner-Weir S, Weissleder R

Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes Diabetes. 2001;50:2231-6 - PMID: 11574403 - DOI: 10.2337/diabetes.50.10.2231

Russo LM, del Re E, Brown D, Lin HY

Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor. Diabetes. 2007;56(2):380-8 - PMID: 17259382 - DOI: 10.2337/db06-1018

Cruz DN, Perazella MA, Bellomo R, de Cal M, Polanco N, Corradi V, Lentini P, Nalesso F, Ueno T, Ranieri VM, Ronco C

Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review. Crit Care. 2008;11(2):R47 - PMID: 17448226 - PMCID: PMC2206475 - DOI: 10.1186/cc5780

McCarthy JR, Korngold E, Weissleder R, Jaffer FA

A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis. Small. 2010;6(18):2041-9 - PMID: 20721949 - PMCID: PMC3018665 - DOI: 10.1002/smll.201000596

McCarthy J, Jaffer F, Weissleder R.

A Macrophage Targeted Theranostic Nanoparticle for Biomedical Applications Small. 2006;2(8-9):983-987 - PMID: 17193154 - DOI: 10.1002/smll.200600139

Sun EY, Weissleder R, Josephson L.

Continuous Analyte Sensing with Magnetic Nanoswitches Small. 2006;(2) 10:1144-1147 - PMID: 17193579 - DOI: 10.1002/smll.200600204

Hingtgen SD, Kasmieh R, van de Water J, Weissleder R, Shah K

Determining Multiple Aspects of Stem Cell-Based Therapies Using Novel Diagnostic and Therapeutic Multifunctional Molecules. Stem Cells. 2010;28(4):832-41 - PMID: 20127797 - PMCID: PMC3021283 - DOI: 10.1002/stem.313

Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, Macdonald ME, Seong IS

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis. Hum Mol Genet. 2011;20(12):2344-55 - PMID: 21447599 - PMCID: PMC3098733 - DOI: 10.1093/hmg/ddr127

Hewett J, Nery F, Niland B, Ge P, Tan P, Hadwiger P, Tannous B, Sah D, Breakefield X

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells. Hum Mol Genet. 2008;17:1436-45 - PMID: 18258738 - PMCID: PMC2861568 - DOI: 10.1093/hmg/ddn032

McCarthy J, Kelly KA, Sun EY, Weissleder R.

Targeted delivery of multifunctional magnetic nanoparticles Nanomedicine. 2007;2(2):153-167 - PMID: 17716118 - DOI: 10.2217/17435889.2.2.153

Martinez-Boubeta C, Balcells L, Cristool R, Sanfeliu C, Rodriguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martinez B

Self-assembled Multifunctional Fe/MgO Nanospheres for Magnetic Resonance Imaging and Hyperthermia. Nanomedicine. 2009;6(2):362-370 - PMID: 19800988 - DOI: 10.1016/j.nano.2009.09.003

McCarthy JR

The future of theranostic nanoagents. Nanomedicine. 2009;4(7):693-5 - PMID: 19839803 - DOI: 10.2217/nnm.09.58

Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS

The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells. Biomaterials . 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971 - DOI: 10.1016/j.biomaterials.2009.10.019

Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA

Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction. Biomaterials . 2010;32(4):1102-9 - PMID: 21035182 - PMCID: PMC6805145 - DOI: 10.1016/j.biomaterials.2010.10.005

Engelmayr G, Rabkin E, Sutherland F, Schoen F, Mayer J, Sacks M

The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue. Biomaterials . 2005;26:175-87 - PMID: 15207464 - DOI: 10.1016/j.biomaterials.2004.02.035

Im H, Wittenberg NJ, Lesuffleur A, Lindquist NC, Oh SH

Membrane protein biosensing with plasmonic nanopore arrays and pore-spanning lipid membranes. Chem Sci. 2010;1(6):688-696 - PMID: 21218136 - PMCID: PMC3015192 - DOI: 10.1039/C0SC00365D

Sosnovik DE, Weissleder R

Emerging concepts in molecular MRI. Curr Opin Biotech. 2007;18(1):4-10 - PMID: 17126545 - DOI: 10.1016/j.copbio.2006.11.001

Wunder A, Tung CH, Muller-Ladner U, Weissleder R, Mahmood U

In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arth Rheum/AR C Res. 2004;50(8):2459-65 - PMID: 15334458 - DOI: 10.1002/art.20379

Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arth Rheum/AR C Res. 2007;56(1):117-128 - PMID: 17195214 - DOI: 10.1002/art.22303

Mendenhall E, Bernstein B

Chromatin state maps: new technologies, new insights. Curr Opin Genet Dev. 2008;18(2):109-15 - PMID: 18339538 - PMCID: PMC2486450 - DOI: 10.1016/j.gde.2008.01.010

Khazaie K, von Boehmer H

The impact of CD4(+)CD25(+) Treg on tumor specific CD8(+) T cell cytotoxicity and cancer. Semin Cancer Biol. 2006;16(2):124-136 - PMID: 16443370 - DOI: 10.1016/j.semcancer.2005.11.006

Speiser D, Pittet M, Rimoldi D, Guillaume P, Luescher I, Lienard D, Lejeune F, Cerottini J, Romero P

Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. Semin Cancer Biol. 2003;13:461-72 - PMID: 15001165 - DOI: 10.1016/j.semcancer.2003.09.010

Shah K, Tang Y, Breakefield X, Weissleder R

Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo Oncogene. 2003;22:6865-72 - PMID: 14534533 - DOI: 10.1038/sj.onc.1206748

van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K

Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene. 2010;29(22):3185-95 - PMID: 20305695 - PMCID: PMC3390229 - DOI: 10.1038/onc.2010.75

Helman E, Naxerova K, Kohane IS

DNA hypermethylation in lung cancer is targeted at differentiation-associated genes. Oncogene. 2011;31(9):1181-8 - PMID: 21804601 - DOI: 10.1038/onc.2011.307

Trink B, Pai SI, Spunt SL, Raman V, Cairns P, Jen J, Gabrielson E, Sukumar S, Sidransky D

Absence of TSG101 transcript abnormalities in human cancers. Oncogene. 1998;16(21):2815-8 - PMID: 9652749 - DOI: 10.1038/sj.onc.1201795

Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P

Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma. Mol Ther. 2010;18(6):1130-42 - PMID: 20179672 - PMCID: PMC2889737 - DOI: 10.1038/mt.2010.29

Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL

Bevacizumab With Angiostatin-armed oHSV Increases Antiangiogenesis and Decreases Bevacizumab-induced Invasion in U87 Glioma. Mol Ther. 2011;20(1):37-45 - PMID: 21915104 - PMCID: PMC3255598 - DOI: 10.1038/mt.2011.187

Noh KH, Kang TH, Kim JH, Pai SI, Lin KY, Hung CF, Wu TC, Kim TW

Activation of Akt as a mechanism for tumor immune evasion. Mol Ther. 2008;17(3):439-47 - PMID: 19107122 - PMCID: PMC2835083 - DOI: 10.1038/mt.2008.255

Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO.

Codon-optimized gaussia luciferase cDNA for Mammalian gene expression in culture and in vivo Mol Ther. 2005;11(3):435-43 - PMID: 15727940 - DOI: 10.1016/j.ymthe.2004.10.016

Shah K, Tung CH, Breakefield X, Weissleder R.

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis Mol Ther. 2005;11 (6):926-931 - PMID: 15922963 - DOI: 10.1016/j.ymthe.2005.01.017

Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA

Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging. Mol Ther. 2006;4(6):779-88 - PMID: 16996314 - PMCID: PMC2819149 - DOI: 10.1016/j.ymthe.2006.08.008

Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R.

Mapping of nodal disease in locally advanced prostate cancer: Rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy Int J Radiat Oncol Biol Phys. 2005;63(4):1262-9 - PMID: 16253781 - DOI: 10.1016/j.ijrobp.2005.07.952

Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG

Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009;74(4):1207-16 - PMID: 19545786 - PMCID: PMC2733223 - DOI: 10.1016/j.ijrobp.2009.02.052

Macdonald SM, Harisinghani MG, Katkar A, Napolitano B, Wolfgang J, Taghian AG

Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer. Int J Radiat Oncol Biol Phys. 2009;77(4):1098-104 - PMID: 19836160 - DOI: 10.1016/j.ijrobp.2009.06.002

Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T

Imaging Primary Lung Cancers in Mice to Study Radiation Biology. Int J Radiat Oncol Biol Phys. 2010;76(4):973-977 - PMID: 20206017 - PMCID: PMC2847457 - DOI: 10.1016/j.ijrobp.2009.11.038

Kirsch DG, Grimm J, Guimaraes AR, Weissleder R

In response to dr. Garbow and colleagues. Int J Radiat Oncol Biol Phys. 2011;79(3):959 - PMID: 21281902

Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ

WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud. Curr Top Dev Biol. 2010;20(22):1993-2002 - PMID: 21055947 - PMCID: PMC2998074 - DOI: 10.1016/j.cub.2010.09.063

Basilion JP, Yeon S, Botnar R

Magnetic Resonance Imaging: Utility as a Molecular Imaging Modality. Curr Top Dev Biol. 2005;70(c):1-33 - PMID: 16338335 - DOI: 10.1016/S0070-2153(05)70001-6

Mahmood U, Josephson L

Molecular MR Imaging Probes P IEEE. 0;93 (4):800-808

Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R

Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008;28:4406-13 - PMID: 18434519 - PMCID: PMC3021321 - DOI: 10.1523/JNEUROSCI.0296-08.2008

Samad T, Srinivasan A, Karchewski L, Jeong S, Campagna J, Ji R, Fabrizio D, Zhang Y, Lin HY, Bell E, Woolf C

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci. 2004;24(8):2027-36 - PMID: 14985445 - PMCID: PMC6730385 - DOI: 10.1523/JNEUROSCI.4115-03.2004

Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, Inquimbert P, Niederkofler V, Salie R, Sun CC, Lin HY, Arber S, Coppola G, Woolf CJ, Samad TA

The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling. J Neurosci. 2011;31(50):18391-18400 - PMID: 22171041 - PMCID: PMC3243947 - DOI: 10.1523/JNEUROSCI.4550-11.2011

Lee H, Liu Y, Ham D, Westervelt RM

Integrated cell manipulation system--CMOS/microfluidic hybrid. Lab Chip. 2007;7(3):331-7 - PMID: 17330164 - DOI: 10.1039/b700373k

Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H

Self-assembled magnetic filter for highly efficient immunomagnetic separation. Lab Chip. 2010;11(1):147-51 - PMID: 20949198 - PMCID: PMC3005961 - DOI: 10.1039/c0lc00149j

Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H

Miniature magnetic resonance system for point-of-care diagnostics. Lab Chip. 2011;11(13):2282-7 - PMID: 21547317 - PMCID: PMC3115660 - DOI: 10.1039/c1lc20177h

Lindquist NC, Lesuffleur A, Im H, Oh SH

Sub-micron resolution surface plasmon resonance imaging enabled by nanohole arrays with surrounding Bragg mirrors for enhanced sensitivity and isolation. Lab Chip. 2008;9(3):382-7 - PMID: 19156286 - DOI: 10.1039/b816735d

Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ

Genetic and Clinical Correlates of Early Outgrowth Colony Forming Units. Circ Cardiovasc Genet. 2011;4(3):296-304 - PMID: 21493818 - PMCID: PMC3339257 - DOI: 10.1161/CIRCGENETICS.110.958470

McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R

Targeted nanoagents for the detection of cancers. Mol Oncol. 2010;4(6):511-28 - PMID: 20851695 - PMCID: PMC2981649 - DOI: 10.1016/j.molonc.2010.08.003

Niers JM, Chen JW, Weissleder R, Tannous BA

Enhanced in Vivo Imaging of Metabolically Biotinylated Cell Surface Reporters. Anal Chem. 2011;83(3):994-9 - PMID: 21214190 - PMCID: PMC3059349 - DOI: 10.1021/ac102758m

Im H, Lesuffleur A, Lindquist NC, Oh SH

Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing. Anal Chem. 2009;81(8):2854-9 - PMID: 19284776 - PMCID: PMC2720634 - DOI: 10.1021/ac802276x

Tsourkas A, Newton G, Perez JM, Basilion J, Weissleder R.

Detection of Peroxidase-Mediated Dityrosine Formation with Enhanced Yellow Fluorescent Protein Anal Chem. 2005;77:2862-2867 - PMID: 15859603 - DOI: 10.1021/ac0480747

Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L

Multiparameter Magnetic Relaxation Switch Assays. Anal Chem. 2007;(79) 23:8863-9 - PMID: 17983206 - DOI: 10.1021/ac701976p

Koh I, Hong R, Weissleder R, Josephson L

Nanoparticle-Target Interactions Parallel Antibody-Protein Interactions. Anal Chem. 2009;81(9):3618-22 - PMID: 19323458 - PMCID: PMC2690647 - DOI: 10.1021/ac802717c

Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R

MRI of a Novel Murine Working Heart Transplant Model Circ Heart Fail. 2009;2:272-274 - PMID: 19718275 - PMCID: PMC2733535 - DOI: 10.1161/CIRCHEARTFAILURE.109.852707

Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R

Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors. Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251 - DOI: 10.1161/ATVBAHA.109.193086

Deguchi JO, Yamazaki H, Aikawa E, Aikawa M

Chronic Hypoxia Activates the Akt and {beta}-Catenin Pathways in Human Macrophages. Arterioscler Thromb Vasc Biol. 2009;29(10):1664-70 - PMID: 19644051 - DOI: 10.1161/ATVBAHA.109.194043

Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA

Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis. Novel Detection by Dual-Target Fluorescence Molecular Imaging. Arterioscler Thromb Vasc Biol. 2010;30(10):1933-9 - PMID: 20689078 - PMCID: PMC3030475 - DOI: 10.1161/ATVBAHA.110.206342

Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R

Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography-Computed Tomography. Arterioscler Thromb Vasc Biol. 2011;31(4):750-7 - PMID: 21252070 - PMCID: PMC3060293 - DOI: 10.1161/ATVBAHA.110.221499

Swirski FK

The spatial and developmental relationships in the macrophage family. Arterioscler Thromb Vasc Biol. 2011;31(7):1517-22 - PMID: 21677294 - PMCID: PMC3117206 - DOI: 10.1161/ATVBAHA.110.221150

Jaffer FA, Tung CH, Gerszten RE, Weissleder R

In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe Arterioscler Thromb Vasc Biol. 2002;22:1929-35 - PMID: 12426227 - DOI: 10.1161/01.atv.0000033089.56970.2d

Simoncini T, Rabkin E, Liao J

Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells. Arterioscler Thromb Vasc Biol. 2003;23:198-203 - PMID: 12588759 - DOI: 10.1161/01.atv.0000053846.71621.93

Jaffer FA, Libby P, Weissleder R

Optical and Multimodality Molecular Imaging. Insights Into Atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29(7):1017-24 - PMID: 19359659 - PMCID: PMC2733228 - DOI: 10.1161/ATVBAHA.108.165530

Swirski FK, Weissleder R, Pittet MJ

Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29(10):1424-32 - PMID: 19372462 - PMCID: PMC2746262 - DOI: 10.1161/ATVBAHA.108.180521

Querol M, Chen JW, Weissleder R, Bogdanov A Jr.

DTPA-bisamide-Based MR Sensor Agents for Peroxidase Imaging Org Lett. 2005;7(9):1719-22 - PMID: 15844889 - DOI: 10.1021/ol050208v

Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA

A Highly Selective Fluorescent Probe for Thiol Bioimaging. Org Lett. 2007;10 :37-40 - PMID: 18062694 - DOI: 10.1021/ol702539v

McCarthy JR, Jenkins HA, Bruckner C

Free base meso-tetraaryl-morpholinochlorins and porpholactone from meso-tetraaryl-2,3-dihydroxy-chlorin. Org Lett. 2003;5(1):19-22

Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R

A Concise Silylamine Approach to 2-Amino-3-hydroxy-indoles with Potent in vivo Antimalaria Activity. Org Lett. 2010;12(18):3998-4001 - PMID: 20718474 - PMCID: PMC7479540 - DOI: 10.1021/ol101566h

Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R

Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun. 2009;28:4188-90 - PMID: 19585016 - PMCID: PMC2748243 - DOI: 10.1039/b905927j

Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L

A DNA-binding Gd chelate for the detection of cell death by MRI. Chem Commun. 2009;(29):4444-6 - PMID: 19597620 - PMCID: PMC2754278 - DOI: 10.1039/b907375b

Hilderbrand S, Weissleder R.

Optimized pH-responsive cyanine fluorochromes for detection of acidic environments Chem Commun. 2007;(26):2747-9 - PMID: 17594041 - DOI: 10.1039/b703764c

Kim YM, Hilderbrand S, Weissleder R, Tung CH

Sugar sensing based on induced pH changes Chem Commun. 2007;(22):2299-2301 - PMID: 17534523 - DOI: 10.1039/b700741h

McCarthy JR, Hyland MA, Bruckner C

Indaphyrin, a meso-tetraphenylsecochlorin-derived chromophore incorporating o-phenyl-to-β-linkages Chem Commun. 2003;:1738-9

Garanger E, Aikawa E, Reynolds F, Weissleder R, Josephson L

Simplified syntheses of complex multifunctional nanomaterials. Chem Commun. 2008;39:4792-4 - PMID: 18830495 - PMCID: PMC2692914 - DOI: 10.1039/b809537j

McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW

Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy. Neuroimage. 2008;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022

Hyde D, de Kleine R, MacLaurin S, Miller E, Brooks D, Krucker T, Ntziachristos V

Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model. Neuroimage. 2009;44(4):1304-11 - PMID: 19041402 - DOI: 10.1016/j.neuroimage.2008.10.038

Hendricks JA, Keliher EJ, Marinelli B, Reiner T, Weissleder R, Mazitschek R

In Vivo PET-imaging of Histone Deacetylases by 18F-Suberoylanilide Hydroxamic Acid (18F-SAHA). J Med Chem. 2011;54(15):5576-82 - PMID: 21721525 - PMCID: PMC3150598 - DOI: 10.1021/jm200620f

Kissau L, Stahl P, Mazitschek R, Giannis A, Waldmann H

Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold. J Med Chem. 2003;46(14):2917-31 - PMID: 12825933 - DOI: 10.1021/jm0307943

Yuan H, Luo J, Weissleder R, Cantley L, Josephson L

Wortmannin-C20 Conjugates Generate Wortmannin. J Med Chem. 2006;49(2):740-747 - PMID: 16420059 - DOI: 10.1021/jm050699p

Galande A, Hilderbrand S, Weissleder R, Tung CH.

Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core J Med Chem. 2006;49(15):4715-20 - PMID: 16854078 - DOI: 10.1021/jm051001a

Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L.

Multivalent effects of RGD peptides obtained by nanoparticle display J Med Chem. 2006;49(20):6087-6093

Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L

Slow Self-Activation Enhances The Potency of Viridin Prodrugs. J Med Chem. 2008;51(15):4699-707 - PMID: 18630894 - PMCID: PMC2663427 - DOI: 10.1021/jm800374f

Estiu G, Greenberg E, Harrison C, Kwiatkowski N, Mazitschek R, Bradner J, Wiest O

Structural origin of selectivity in class II-selective histone deacetylase inhibitors. J Med Chem. 2008;51:2898-906 - PMID: 18412327 - DOI: 10.1021/jm7015254

Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J

Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum. J Med Chem. 2009;52(8):2185-7 - PMID: 19317450 - PMCID: PMC2669731 - DOI: 10.1021/jm801654y

Lewin M, Bredow S, Sergeyev N, Marecos E, Bogdanov A Jr, Weissleder R

In vivo assessment of vascular endothelial growth factor-induced angiogenesis Int J Cancer. 1999;83:798-802 - PMID: 10597197 - DOI: 10.1002/(sici)1097-0215(19991210)83:6<798::aid-ijc16>3.0.co;2-w

Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U.

A novel mouse model for segmental orthotopic colon cancer Int J Cancer. 2005;117(3):335-9 - PMID: 15900588 - DOI: 10.1002/ijc.21185

Figueiredo JL, Alencar H, Weissleder R, Mahmood U

Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006;118(11):2672-7 - PMID: 16380983 - DOI: 10.1002/ijc.21713

Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U

Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007;(121) 11:2492-2500 - PMID: 17683072 - DOI: 10.1002/ijc.22995

Kirkin V, Thiele W, Baumann P, Mazitschek R, Rohde K, Fellbrich G, Weich H, Waltenberger J, Giannis A, Sleeman JP

MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo. Int J Cancer. 2004;112(6):986-93 - PMID: 15386354 - DOI: 10.1002/ijc.20509

Lacy-Hulbert A*, Ueno T*, Ito T, Jurewicz M, Izawa A, Smith RN, Chase CM, Tanaka K, Fiorina P, Russell PS, Auchincloss H, Sayegh MH, Hynes RO, Abdi R

Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection. Am J Transplant. 2007;7(5):1080-90 - PMID: 17359504 - DOI: 10.1111/j.1600-6143.2007.01757.x

Yamaura K, Boenisch O, Watanabe T, Ueno T, Vanguri V, Yang J, Tanaka K, Guleria I, Borst J, Zhai Y, Kupiec-Weglinski JW, Najafian N

Differential Requirement of CD27 Costimulatory Signaling for Naive Versus Alloantigen-Primed Effector/Memory CD8(+) T Cells. Am J Transplant. 2010;10(5):1210-20 - PMID: 20353477 - PMCID: PMC2889922 - DOI: 10.1111/j.1600-6143.2010.03089.x

Jurewicz M, Ueno T, Azzi J, Tanaka K, Murayama T, Yang S, Sayegh MH, Niimi M, Abdi R

Donor Antioxidant Strategy Prolongs Cardiac Allograft Survival by Attenuating Tissue Dendritic Cell Immunogenicity. Am J Transplant. 2010;11(2):348-355 - PMID: 21182586 - DOI: 10.1111/j.1600-6143.2010.03360.x

Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R

Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors. Chem Biol. 2011;18(12):1602-10 - PMID: 22195562 - PMCID: PMC3474356 - DOI: 10.1016/j.chembiol.2011.09.016

Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN

A robust small-molecule microarray platform for screening cell lysates. Chem Biol. 2006;13(5):493-504 - PMID: 16720270 - DOI: 10.1016/j.chembiol.2006.03.004

Law B, Curino A, Bugge TH, Weissleder R, Tung CH

Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter. Chem Biol. 2004;11(1):99-106 - PMID: 15112999 - DOI: 10.1016/j.chembiol.2003.12.017

Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L

Covalent Reactions of Wortmannin under Physiological Conditions. Chem Biol. 2007;14(3):321-8 - PMID: 17379147 - DOI: 10.1016/j.chembiol.2007.02.007

Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P

A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chem Biol. 2007;14:1221-31 - PMID: 18022561 - PMCID: PMC2785040 - DOI: 10.1016/j.chembiol.2007.10.005

Kozloff KM, Weissleder R, Mahmood U

Non-Invasive Optical Detection of Bone Mineral. J Bone Miner Res. 2007;(22) 8:1208-1216 - PMID: 17488196 - DOI: 10.1359/jbmr.070504

Quillard T, Croce K, Jaffer FA, Weissleder R, Libby P

Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo. Thromb Haemostasis. 2011;105(5):828-36 - PMID: 21225096 - PMCID: PMC3087830 - DOI: 10.1160/TH10-09-0589

Sosnovik DE, Nahrendorf M, Weissleder R

Targeted imaging of myocardial damage. Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275 - DOI: 10.1038/ncpcardio1115

Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O

Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476 - DOI: 10.1161/CIRCEP.108.778357

Sosnovik DE, Nahrendorf M, Weissleder R

Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271 - DOI: 10.1007/s00395-008-0710-7

Nahrendorf M, Sosnovik DE, Weissleder R

MR-optical imaging of cardiovascular molecular targets. Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635 - DOI: 10.1007/s00395-008-0707-2

Groen A, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison T

A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci. 2008;121(Pt 14):2293-300 - PMID: 18559893 - PMCID: PMC2902979 - DOI: 10.1242/jcs.024018

Zilberman Y, Ballestrem C, Carramusa L, Mazitschek R, Khochbin S, Bershadsky A

Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6. J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819 - DOI: 10.1242/jcs.046813

Tran AD, Marmo TP, Salam AA, Che S, Finkelstein E, Kabarriti R, Xenias HS, Mazitschek R, Hubbert C, Kawaguchi Y, Sheetz MP, Yao TP, Bulinski JC

HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions. J Cell Sci. 2007;120(Pt 8):1469-79 - PMID: 17389687 - DOI: 10.1242/jcs.03431

Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ and Wedeen VJ

Diffusion Spectrum MRI Tractography Reveals the Presence of a Complex Network of Residual Myofibers in Infarcted Myocardium Circ Cardiovasc Imaging. 2009;2:206-212 - PMID: 19808594 - PMCID: PMC2760045 - DOI: 10.1161/CIRCIMAGING.108.815050

Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A

Molecular MRI Detects Low Levels of Cardiomyocyte Apoptosis in a Transgenic Model of Chronic Heart Failure. Circ Cardiovasc Imaging. 2009;2(6):468-475 - PMID: 19920045 - PMCID: PMC2782621 - DOI: 10.1161/CIRCIMAGING.109.863779

Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L

Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia. Circ Cardiovasc Imaging. 2009;2(6):460-467 - PMID: 19920044 - PMCID: PMC2780438 - DOI: 10.1161/CIRCIMAGING.109.859678

Nordbeck P, Hiller KH, Fidler F, Warmuth M, Burkard N, Nahrendorf M, Jakob PM, Quick HH, Ertl G, Bauer WR, Ritter O

Feasibility of Contrast Enhanced and Non-Enhanced MRI for Intra- and Postprocedural Lesion Visualization in Interventional Electrophysiology: Animal Studies and Early Delineation of Isthmus Ablation Lesions in Patients with Typical Atrial Flutter. Circ Cardiovasc Imaging. 2011;4(3):282-94 - PMID: 21415125 - DOI: 10.1161/CIRCIMAGING.110.957670

Nahrendorf M

Imaging of infarct healing predicts left ventricular remodeling and evolution of heart failure: focus on protease activity. Circ Cardiovasc Imaging. 2011;4(4):351-3 - PMID: 21772011 - PMCID: PMC3141180 - DOI: 10.1161/CIRCIMAGING.111.966671

Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE

Molecular MRI of Acute Necrosis with a Novel DNA-Binding Gadolinium Chelate: Kinetics of Cell Death and Clearance in Infarcted Myocardium. Circ Cardiovasc Imaging. 2011;4(6):729-737 - PMID: 21836081 - PMCID: PMC3370828 - DOI: 10.1161/CIRCIMAGING.111.966374

Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA and Gropler RJ

Multimodality Cardiovascular Molecular Imaging, Part I Circ Cardiovasc Imaging. 2008;1(3):244-256 - PMID: 19808549 - DOI: 10.1161/CIRCIMAGING.108.824359

Nahrendorf M, Sosnovik D, French B, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ

Multimodality Cardiovascular Molecular Imaging, Part II Circ Cardiovasc Imaging. 2009;2:56-70 - PMID: 19808565 - PMCID: PMC2760054 - DOI: 10.1161/CIRCIMAGING.108.839092

Nahrendorf M, Wiesmann F, Hiller K, Han H, Hu K, Waller C, Ruff J, Haase A, Ertl G, Bauer W

In vivo assessment of cardiac remodeling after myocardial infarction in rats by cine-magnetic resonance imaging. J Cardiovasc Magn Reson. 2001;2(3):171-80 - PMID: 11545114 - DOI: 10.3109/10976640009146565

Sosnovik DE, Caravan P

Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents J Cardiovasc Magn Reson. 2009;2:87-94

Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ

Diffusion MR tractography of the heart. J Cardiovasc Magn Reson. 2009;11(1):47 - PMID: 19912654 - PMCID: PMC2781805 - DOI: 10.1186/1532-429X-11-47

Law B, Weissleder R, Tung CH

Peptide-based Biomaterials for Protease-Enhanced Drug Delivery Biomacromolecules. 2006;7(4):1261-1265 - PMID: 16602747 - DOI: 10.1021/bm050920f

Law B, Tung CH

Structural modification of protease inducible preprogrammed nanofiber precursor. Biomacromolecules. 2008;9:421-5 - PMID: 18177006 - DOI: 10.1021/bm7012026

Yoshida S, Shimada M, Ueno T, Kitamura Y, Matsuzaki S, Nishikubo S, Nagae M, Nakanishi K, Murata J, Yoshino M

Successful endoscopic submucosal dissection of duodenal cancer. Endoscopy. 2008;40 Suppl 2:E132-3 - PMID: 18633861 - DOI: 10.1055/s-2007-995685

Yoshida S, Shimada M, Ueno T, Kato A, Yoshino M

Latex hand glove: a safe and convenient device for the endoscopic removal of foreign bodies. Endoscopy. 2008;40 Suppl 2:E195-6 - PMID: 18709613 - DOI: 10.1055/s-2008-1077420

Yoshida S, Shimada M, Ueno T, Yoshino M

Exuberant mucosal granulation by a self-expanding metal stent leading to complete closure of esophageal perforation. Endoscopy. 2008;40 Suppl 2:E244-5 - PMID: 18991221 - DOI: 10.1055/s-2008-1077526

Schellenberger EA, Bogdanov A Jr, Petrovsky A, Ntziachristos V, Weissleder R, Josephson L

Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy Neoplasia. 2003;5:187-92 - PMID: 12869301 - PMCID: PMC1502408 - DOI: 10.1016/S1476-5586(03)80050-7

Allport JR, Weissleder R

Murine Lewis lung carcinoma-derived endothelium expresses markers of endothelial activation and requires tumor-specific extracellular matrix in vitro Neoplasia. 2003;5:205-17 - PMID: 12869304 - PMCID: PMC1502407 - DOI: 10.1016/S1476-5586(03)80053-2

Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO

Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2 Neoplasia. 2002;4:501-9 - PMID: 12407444 - PMCID: PMC1503664 - DOI: 10.1038/sj.neo.7900265

Melder RJ, Munn LL, Stoll BR, Marecos EM, Baxter LT, Weissleder R, Jain RK

Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: comparison with physiologically based pharmacokinetic model Neoplasia. 2002;4:3-8 - PMID: 11922388 - PMCID: PMC1503314 - DOI: 10.1038/sj/neo/7900209

Ichikawa T, Hogemann D, Saeki Y, Tyminski E, Terada K, Weissleder R, Chiocca EA, Basilion JP

MRI of transgene expression: correlation to therapeutic gene expression Neoplasia. 2002;4:523-30 - PMID: 12407446 - PMCID: PMC1503666 - DOI: 10.1038/sj.neo.7900266

Bogdanov AA Jr, Lin CP, Simonova M, Matuszewski L, Weissleder R

Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment Neoplasia. 2002;4:228-36 - PMID: 11988842 - PMCID: PMC1531696 - DOI: 10.1038/sj/neo/7900238

Bogdanov A Jr, Marecos E, Cheng HC, Chandrasekaran L, Krutzsch HC, Roberts DD, Weissleder R

Treatment of experimental brain tumors with trombospondin-1 derived peptides: an in vivo imaging study Neoplasia. 1999;1:438-45 - PMID: 10933059 - PMCID: PMC1508110 - DOI: 10.1038/sj.neo.7900044

Hogemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP.

The transferrin receptor: a potential molecular imaging marker for human cancer. Neoplasia. 2003;5(6):495-506 - PMID: 14965443 - PMCID: PMC1502574 - DOI: 10.1016/s1476-5586(03)80034-9

Messerli SM, Prabhakar S, Tang Y, Shah K, Cortes ML, Murthy V, Weissleder R, Breakefield XO, Tung CH

A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. Neoplasia. 2004;6(2):95-105 - PMID: 15140398 - PMCID: PMC1502090 - DOI: 10.1593/neo.03214

Shinde Patil VR, Friedrich EB, Wolley AE, Gerszten RE, Allport JR, Weissleder R.

Bone Marrow-Derived lin(-)c-kit(+)Sca-1(+) Stem Cells Do Not Contribute to Vasculogenesis in Lewis Lung Carcinoma Neoplasia. 2005;7(3):234-40 - PMID: 15799823 - PMCID: PMC1501134 - DOI: 10.1593/neo.04523

Reichardt W, Hu-Lowe D, Torres D, Weissleder R, Bogdanov A Jr.

Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model Neoplasia. 2005;7(9):847-53 - PMID: 16229807 - PMCID: PMC1351316 - DOI: 10.1593/neo.05139

Funovics M, Montet X, Reynolds F, Weissleder R, Josephson L.

Nanoparticles for the Optical Imaging of Tumor E-selectin Neoplasia. 2005;7(10):904-11 - PMID: 16242073 - DOI: 10.1593/neo.05352

Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R

Novel Multiwavelength Microscopic Scanner for Mouse Imaging. Neoplasia. 2005;7(11):977-983 - PMID: 16331883 - PMCID: PMC1502018 - DOI: 10.1593/neo.05376

Sato F, Fukuhara H, Basilion JP

Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo. Neoplasia. 2005;7(9):838-46 - PMID: 16229806 - PMCID: PMC1501932 - DOI: 10.1593/neo.05145

Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L.

Nanoparticle Imaging of Integrins on Tumor Cells Neoplasia. 2006;8(3):214-222 - PMID: 16611415 - PMCID: PMC1578521 - DOI: 10.1593/neo.05769

Trehin R, Figueiredo JL, Pittet M, Weissleder R, Josephson L, Mahmood U.

Fluorescent Nanoparticle Uptake for Brain Tumor Visualization Neoplasia. 2006;8(4):302-311 - PMID: 16756722 - PMCID: PMC1600680 - DOI: 10.1593/neo.05751

Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL

In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006;8(9):772-80 - PMID: 16984734 - PMCID: PMC1584300 - DOI: 10.1593/neo.06331

Kelly KA, Waterman P, Weissleder R.

In vivo imaging of molecularly targeted phage Neoplasia. 2006;8 (12):1011-1018

Kock N, Kasmieh R, Weissleder R, Shah K

Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL. Neoplasia. 2007;9(5):435-42 - PMID: 17534449 - PMCID: PMC1877976 - DOI: 10.1593/neo.07223

Harisinghani M, Ross R, Guimaraes A, Weissleder R

Utility of a New Bolus-Injectable Nanoparticle for Clinical Cancer Staging Neoplasia. 2007;(9)12:1160-1165 - PMID: 18084623 - PMCID: PMC2134912 - DOI: 10.1593/neo.07940

Kelly K, Jones D

Isolation of a colon tumor specific binding peptide using phage display selection. Neoplasia. 2003;5:437-44 - PMID: 14670181 - PMCID: PMC1550331 - DOI: 10.1016/s1476-5586(03)80046-5

Perez JM, Grimm J, Josephson L, Weissleder R

Integrated nanosensors to determine levels and functional activity of human telomerase. Neoplasia. 2008;10(10):1066-72 - PMID: 18813356 - PMCID: PMC2546593 - DOI: 10.1593/neo.08350

Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton A, Waterman P, Figueiredo JL, Kohler R, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ

Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle Neoplasia. 2009;11(5):459-468 - PMID: 19412430 - PMCID: PMC2672160 - DOI: 10.1593/neo.09356

Kim DE, Jaffer FA, Weissleder R, Tung CH, Schellingerhout D.

Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis J Cereb Blood Flow Metab. 2005;25(2):226-33 - PMID: 15678125 - DOI: 10.1038/sj.jcbfm.9600023

Robbins CS, Swirski FK

The multiple roles of monocyte subsets in steady state and inflammation. Cell Mol Life Sci. 2010;67(16):2685-93 - PMID: 20437077 - PMCID: PMC11115635 - DOI: 10.1007/s00018-010-0375-x

Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L

The antiproliferative cytostatic effects of a self-activating viridin prodrug. Mol Cancer Ther. 2009;8(6):1666-1675 - PMID: 19509266 - PMCID: PMC2740925 - DOI: 10.1158/1535-7163.MCT-08-1012

Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B

Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1. Mol Cancer Ther. 2009;18(2):285-94 - PMID: 19844198 - PMCID: PMC2818668 - DOI: 10.1038/mt.2009.232

Emdad L, Sarkar D, Lee SG, Su ZZ, Yoo BK, Dash R, Yacoub A, Fuller CE, Shah K, Dent P, Bruce JN, Fisher PB

Astrocyte elevated gene-1: a novel target for human glioma therapy. Mol Cancer Ther. 2010;9(1):79-88 - PMID: 20053777 - PMCID: PMC3165052 - DOI: 10.1158/1535-7163.MCT-09-0752

Mahmood U, Weissleder R

Near-infrared optical imaging of proteases in cancer Mol Cancer Ther. 2003;2:489-96 - PMID: 12748311

Law B, Quinti L, Choi YD, Weissleder R, Tung CH

A Mitochondrial Targeted Fusion Peptide Exhibits Remarkable Cytotoxicity Mol Cancer Ther. 2006;5 (8):1944-1949 - PMID: 16928814 - DOI: 10.1158/1535-7163.MCT-05-0509

Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K

Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol Cancer Ther. 2008;7(11):3575-85 - PMID: 19001440 - PMCID: PMC2748233 - DOI: 10.1158/1535-7163.MCT-08-0640

Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, Garcia-Anoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO

Mutant Sodium Channel for Tumor Therapy. Mol Cancer Ther. 2009;17(5):810-9 - PMID: 19259066 - PMCID: PMC2751883 - DOI: 10.1038/mt.2009.33

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Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control. J Immunol. 2006;176(5):2902-14 - PMID: 16493048 - DOI: 10.4049/jimmunol.176.5.2902

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AUR Memorial Award 1993. A drug system (PDH) for interventional radiology. Synthesis, properties, and efficacy. Invest Radiol. 1993;28(12):1083-9 - PMID: 8307710 - DOI: 10.1097/00004424-199312000-00001

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Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006;64(4):589-97 - PMID: 16996355 - DOI: 10.1016/j.gie.2006.02.048

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Facile Synthesis of Monofunctional Pentamethine Carbocyanine Fluorophores. Dyes Pigm. 2011;90(2):119-122 - PMID: 21475610 - PMCID: PMC3070263 - DOI: 10.1016/j.dyepig.2010.12.008

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Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006;12(5):797-806 - PMID: 16556935 - PMCID: PMC1440893 - DOI: 10.1261/rna.2300406

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Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X

Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005;16:1367-76 - PMID: 16390268 - DOI: 10.1089/hum.2005.16.1367

Messerli SM, Prabhakar S, Tang Y, Mahmood U, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006;17(1):20-30 - PMID: 16409122 - DOI: 10.1089/hum.2006.17.20

Schellingerhout D, Bogdanov A, Marecos E, Spear M, Breakefield X, Weissleder R

Mapping the in vivo distribution of herpes simplex virions. Hum Gene Ther. 1998;9(11):1543-9 - PMID: 9694153 - DOI: 10.1089/hum.1998.9.11-1543

Rainov NG, Zimmer C, Chase M, Kramm CM, Chiocca EA, Weissleder R, Breakefield XO

Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Hum Gene Ther. 1995;6(12):1543-52 - PMID: 8664379 - DOI: 10.1089/hum.1995.6.12-1543

Ji H, Wang TL, Chen CH, Pai SI, Hung CF, Lin KY, Kurman RJ, Pardoll DM, Wu TC

Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors. Hum Gene Ther. 1999;10(17):2727-40 - PMID: 10584920 - DOI: 10.1089/10430349950016474

Sabolic I, Herak-Kramberger CM, Antolovic R, Breton S, Brown D

Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin. Toxicology. 2005;218(2-3):149-63 - PMID: 16288946 - DOI: 10.1016/j.tox.2005.10.009

Iyer VR, Hahn PF, Blaszkowsky LS, Thayer SP, Halpern EF, Harisinghani MG

Added Value of Selected Images Embedded Into Radiology Reports to Referring Clinicians. J Am Coll Radiol. 2010;7(3):205-210 - PMID: 20193926 - PMCID: PMC3086392 - DOI: 10.1016/j.jacr.2009.10.014

Montet X, Yuan H, Weissleder R, Josephson L

Enzyme-based visualization of receptor-ligand binding in tissues. Lab Invest. 2006;86(5):517-25 - PMID: 16568109 - DOI: 10.1038/labinvest.3700404

Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA

Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer. Lab Invest. 2006;86(6):599-609 - PMID: 16607378 - DOI: 10.1038/labinvest.3700421

Deguchi JO, Huang H, Libby P, Aikawa E, Whittaker P, Sylvan J, Lee RT, Aikawa M

Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II. Lab Invest. 2009;89(3):315-26 - PMID: 19153555 - PMCID: PMC2932654 - DOI: 10.1038/labinvest.2008.167

Larson AM, Hedgire SS, Deshpande V, Stemmer-Rachamimov AO, Harisinghani MG, Ferrone CR, Shah U, Thiele EA

Pancreatic neuroendocrine tumors in patients with tuberous sclerosis complex. Clin Genet. 2011;82(6):558-63 - PMID: 22035404 - DOI: 10.1111/j.1399-0004.2011.01805.x

Lienard D, Rimoldi D, Marchand M, Dietrich P, van Baren N, Geldhof C, Batard P, Guillaume P, Ayyoub M, Pittet M, Zippelius A, Fleischhauer K, Lejeune F, Cerottini J, Romero P, Speiser D

Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA. Cancer Immunol Immunther. 2004;4:4 - PMID: 15149168

Kang HW, Weissleder R, Bogdanov A Jr

Targeting of MPEG-protected polyamino acid carrier to human E-selectin in vitro Amino Acids. 2002;23:301-8 - PMID: 12373551 - DOI: 10.1007/s00726-001-0142-2

Pham W, Lai WF, Weissleder R, Tung CH

High efficiency synthesis of a bioconjugatable near-infrared fluorochrome Bioconjug Chem. 2003;14:1048-51 - PMID: 13129411 - DOI: 10.1021/bc034070h

Moon, WK, Lin Y, O'Loughlin T, Tang Y, Kim DE, Weissleder R, Tung CH

Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate Bioconjug Chem. 2003;14:539-45 - PMID: 12757377 - DOI: 10.1021/bc0340114

Koch AM, Reynolds F, Kircher MF, Merkle HP, Weissleder R, Josephson L

Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells Bioconjug Chem. 2003;14:1115-21 - PMID: 14624624 - DOI: 10.1021/bc034123v

Zhao M, Kircher MF, Josephson L, Weissleder R

Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake Bioconjug Chem. 2002;13:840-4 - PMID: 12121140 - DOI: 10.1021/bc0255236

Wunderbaldinger P, Josephson L, Weissleder R

Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles Bioconjug Chem. 2002;13:264-8 - PMID: 11906263 - DOI: 10.1021/bc015563u

Lin Y, Weissleder R, Tung CH

Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation Bioconjug Chem. 2002;13:605-10 - PMID: 12009952 - DOI: 10.1021/bc0155723

Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov A Jr

Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture Bioconjug Chem. 2002;13:122-7 - PMID: 11792187 - DOI: 10.1021/bc0155521

Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R

Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes Bioconjug Chem. 2002;13:554-60 - PMID: 12009946 - DOI: 10.1021/bc015555d

Hogemann D, Ntziachristos V, Josephson L, Weissleder R

High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes Bioconjug Chem. 2002;13:116-21 - PMID: 11792186 - DOI: 10.1021/bc015549h

Weissleder R, Bogdanov A Jr, Tung CH, Weinmann HJ

Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging Bioconjug Chem. 2001;12:213-9 - PMID: 11312682 - DOI: 10.1021/bc000091p

Hogemann D, Josephson L, Weissleder R, Basilion JP

Improvement of MRI probes to allow efficient detection of gene expression Bioconjug Chem. 2000;11:941-6 - PMID: 11087345 - DOI: 10.1021/bc000079x

Bhorade R, Weissleder R, Nakakoshi T, Moore A, Tung CH

Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide Bioconjug Chem. 2000;11:301-5 - PMID: 10821645 - DOI: 10.1021/bc990168d

Tung CH, Bredow S, Mahmood U, Weissleder R

Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging Bioconjug Chem. 1999;10:892-6 - PMID: 10502358 - DOI: 10.1021/bc990052h

Josephson L, Tung CH, Moore A, Weissleder R

High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates Bioconjug Chem. 1999;10:186-91 - PMID: 10077466 - DOI: 10.1021/bc980125h

Kircher MF, Weissleder R, Josephson L

A dual fluorochrome probe for imaging proteases Bioconjug Chem. 2004;15:242-8 - PMID: 15025519 - DOI: 10.1021/bc034151d

Banerjee P, Reichardt W, Weissleder R, Bogdanov A Jr

Novel hyperbranched dendron for gene transfer in vitro and in vivo. Bioconjug Chem. 2004;15(5):960-8 - PMID: 15366948 - DOI: 10.1021/bc0342128

Schellenberger EA, Sosnovik D, Weissleder R, Josephson L

Magneto/Optical annexin v, a multimodal protein. Bioconjug Chem. 2004;15(5):1062-7 - PMID: 15366960 - DOI: 10.1021/bc049905i

Pham W, Choi Y, Weissleder R, Tung CH

Developing a Peptide-Based Near-Infrared Molecular Probe for Protease Sensing. Bioconjug Chem. 2004;15(6):1403-1407 - PMID: 15546208 - DOI: 10.1021/bc049924s

Metelev V, Weissleder R, Bogdanov A Jr

Synthesis and Properties of Fluorescent NF-kappaB-Recognizing Hairpin Oligodeoxyribonucleotide Decoys. Bioconjug Chem. 2004;15(6):1481-1487 - PMID: 15546218 - DOI: 10.1021/bc049916b

Tsourkas A, Shinde-Patil VR, Kelly KA, Patel P, Wolley A, Allport JR, Weissleder R.

In Vivo Imaging of Activated Endothelium Using an Anti-VCAM-1 Magneto optical Probe Bioconjug Chem. 2005;(3):576-581 - PMID: 15898724 - DOI: 10.1021/bc050002e

Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L.

Synthesis and Activity of C11-Modified Wortmannin Probes for P13 Kinase Bioconjug Chem. 2005;(3):669-675 - PMID: 15898736 - DOI: 10.1021/bc049714f

Reynolds F, Weissleder R, Josephson L.

Protamine as an efficient membrane-translocating Peptide Bioconjug Chem. 2005;16(5):1240-5 - PMID: 16173804 - DOI: 10.1021/bc0501451

Hilderbrand SA, Kelly KA, Weissleder R, Tung CH.

Monofunctional near-infrared fluorochromes for imaging applications Bioconjug Chem. 2005;16(5):1275-81 - PMID: 16173808 - DOI: 10.1021/bc0501799

Sun EY, Josephson L, Kelly KA, Weissleder R

Development of nanoparticle libraries for biosensing. Bioconjug Chem. 2006;17(1):109-13 - PMID: 16417258 - DOI: 10.1021/bc050290e

Banerjee P, Weissleder R, Bogdanov A

Linear Polyethyleneimine Grafted to a Hyperbranched Poly(ethylene glycol)-like Core: A Copolymer for Gene Delivery. Bioconjug Chem. 2006;17(1):125-31 - PMID: 16417260 - DOI: 10.1021/bc050083e

Galande A, Weissleder R, Tung CH.

Fluorescence Probe with a pH-Sensitive Trigger Bioconjug Chem. 2006;17 (2):255-257 - PMID: 16536452 - DOI: 10.1021/bc050330e

Montet X, Weissleder R, Josephson L.

Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas Bioconjug Chem. 2006;17(4):905-911 - PMID: 16848396 - DOI: 10.1021/bc060035+

Lai KS, Ho NH, Cheng JD, Tung CH

Selective Fluorescence Probes for Dipeptidyl Peptidase Activity-Fibroblast Activation Protein and Dipeptidyl Peptidase IV. Bioconjug Chem. 2007;18(4):1246-50 - PMID: 17489551 - PMCID: PMC2562575 - DOI: 10.1021/bc0603586

Kim GY, Josephson L, Langer R, Cima MJ

Magnetic Relaxation Switch Detection of Human Chorionic Gonadotrophin. Bioconjug Chem. 2007;18(6):2024-8 - PMID: 17892270 - DOI: 10.1021/bc070110w

Law B, Weissleder R, Tung CH

Protease-Sensitive Fluorescent Nanofibers. Bioconjug Chem. 2007;(18) 6 ::1701-1704 - PMID: 17915958 - PMCID: PMC2528070 - DOI: 10.1021/bc070054z

Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L

Fate of a Bioactive Fluorescent Wortmannin Derivative in Cells. Bioconjug Chem. 2007;19:130-137 - PMID: 17988080 - DOI: 10.1021/bc7002204

Hilderbrand SA, Kelly KA, Niedre M, Weissleder R

Near Infrared Fluorescence-Based Bacteriophage Particles for Ratiometric pH Imaging. Bioconjug Chem. 2008;19(8):1635-9 - PMID: 18666791 - PMCID: PMC2705288 - DOI: 10.1021/bc800188p

Shao F, Weissleder R, Hilderbrand SA

Monofunctional Carbocyanine Dyes for Bio- and Bioorthogonal Conjugation. Bioconjug Chem. 2008;19(12): :2487-2491 - PMID: 19053316 - PMCID: PMC2656649 - DOI: 10.1021/bc800417b

Devaraj N, Weissleder R, Hilderbrand S

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging. Bioconjug Chem. 2008;19(12):2297-2299 - PMID: 19053305 - PMCID: PMC2677645 - DOI: 10.1021/bc8004446

Garanger E, Weissleder R, Josephson L

A Multifunctional Single-Attachment-Point Reagent for Controlled Protein Biotinylation. Bioconjug Chem. 2009;20(1):170-173 - PMID: 19072220 - PMCID: PMC2692913 - DOI: 10.1021/bc800392t

Devaraj NK*, Keliher EJ*, Thurber GM, Nahrendorf M, Weissleder R

(18)F Labeled Nanoparticles for in Vivo PET-CT Imaging. Bioconjug Chem. 2009;20(2):397-401 - PMID: 19138113 - PMCID: PMC2644737 - DOI: 10.1021/bc8004649

McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA

Multimodal Nanoagents for the Detection of Intravascular Thrombi. Bioconjug Chem. 2009;20(6):1251-5 - PMID: 19456115 - PMCID: PMC2733224 - DOI: 10.1021/bc9001163

Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L

A Wortmannin-Cetuximab as a Double Drug. Bioconjug Chem. 2009;20 :2185-2189 - PMID: 19883074 - PMCID: PMC3386608 - DOI: 10.1021/bc900176a

Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY

Binding Affinity and Kinetic Analysis of Targeted Small Molecule-Modified Nanoparticles Bioconjug Chem. 2010;21:14-19 - PMID: 20028085 - PMCID: PMC2902264 - DOI: 10.1021/bc900438a

Reiner T, Kohler RH, Liew CW, Hill JA, Gaglia J, Kulkarni RN, Weissleder R

Near-Infrared Fluorescent Probe for Imaging of Pancreatic B Cells Bioconjug Chem. 2010;21:1362-1368 - PMID: 20583828 - PMCID: PMC2912453 - DOI: 10.1021/bc100184w

Marecos E, Weissleder R, Bogdanov A

Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model. Bioconjug Chem. 1998;9(2):184-91 - PMID: 9548533 - DOI: 10.1021/bc970146w

Shen TT, Bogdanov A, Bogdanova A, Poss K, Brady TJ, Weissleder R

Magnetically labeled secretin retains receptor affinity to pancreas acinar cells. Bioconjug Chem. 1996;7(3):311-6 - PMID: 8816953 - DOI: 10.1021/bc960003u

Bogdanov AA, Martin C, Bogdanova AV, Brady TJ, Weissleder R

An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties. Bioconjug Chem. 1996;7(1):144-9 - PMID: 8742003 - DOI: 10.1021/bc950089b

Zeglis BM, Mohindra P, Weissmann GI, Divilov V, Hilderbrand SA, Weissleder R, Lewis JS

A Modular Strategy for the Construction of Radiometallated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels-Alder Click Chemistry. Bioconjug Chem. 2011;22(10):2048-59 - PMID: 21877749 - PMCID: PMC3197258 - DOI: 10.1021/bc200288d

Karver M, Weissleder R, Hilderbrand SA

Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation. Bioconjug Chem. 2011;22(11):2263-2270 - PMID: 21950520 - PMCID: PMC3254257 - DOI: 10.1021/bc200295y

Keliher E, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet M, Weissleder R

89Zr Labeled Dextran Nanoparticles Enable in vivo Macrophage Imaging. Bioconjug Chem. 2011;22(12):2383-9 - PMID: 22035047 - PMCID: PMC3244512 - DOI: 10.1021/bc200405d

Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R

Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance. Bioconjug Chem. 2011;22(12):2390-4 - PMID: 22043803 - PMCID: PMC3263317 - DOI: 10.1021/bc200490r

Yoshida S, Kurokohchi K, Ueno T, Yoshino M, Shimada M, Masaki T

Hepatic von Meyenburg complex: a trigger of severe portal hypertension. Liver Int. 2008;29(4):614-5 - PMID: 19018981 - PMCID: PMC2711260 - DOI: 10.1111/j.1478-3231.2008.01903.x

Shah K, Weissleder R

Molecular Optical Imaging: Applications Leading to the Development of Present Day Therapeutics NeuroRx. 2005;2:215-225 - PMID: 15897946 - PMCID: PMC1064987 - DOI: 10.1602/neurorx.2.2.215

Brown D, Hasler U, Nunes P, Bouley R, Lu H

Phosphorylation events and the modulation of aquaporin 2 cell surface expression. Curr Opin Nephrol Hypertens. 2008;17(5):491-8 - PMID: 18695390 - PMCID: PMC3774073 - DOI: 10.1097/MNH.0b013e3283094eb1

Comper WD, Russo LM

The glomerular filter: an imperfect barrier is required for perfect renal function. Curr Opin Nephrol Hypertens. 2009;18(4):336-42 - PMID: 19474730 - DOI: 10.1097/MNH.0b013e32832cb96a

Marshansky V, Ausiello DA, Brown D

Physiological importance of endosomal acidification: potential role in proximal tubulopathies. Curr Opin Nephrol Hypertens. 2002;11(5):527-37 - PMID: 12187318 - DOI: 10.1097/00041552-200209000-00009

Xu C, Mu L, Roes I, Miranda-Nieves D, Nahrendorf M, Ankrum JA, Zhao W, Karp JM

Nanoparticle-based monitoring of cell therapy. Nanotechnology. 2011;22(49):494001 - PMID: 22101191 - PMCID: PMC3334527 - DOI: 10.1088/0957-4484/22/49/494001

Huang X, Li Y, Im H, Yarimaga O, Kim J, Jang D, Cho S, Cai W, Choi Y

Morphology-controlled SWCNT/polymeric microsphere arrays by a wet chemical self-assembly technique and their application for sensors Nanotechnology. 2006;17(12):2988

Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U

Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2008;44:190-198 - PMID: 19007918 - PMCID: PMC2656637 - DOI: 10.1016/j.bone.2008.10.036

Wunderbaldinger P, Josephson L, Weissleder R

Crosslinked iron oxides (CLIO): a new platform for the development of targeted MR contrast agents Acad Radiol. 2002;9 Suppl 2:S304-6 - PMID: 12188255 - DOI: 10.1016/s1076-6332(03)80210-6

Schellenberger EA, Hogemann D, Josephson L, Weissleder R

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Acad Radiol. 2002;9 Suppl 2:S310-1 - PMID: 12188257 - DOI: 10.1016/s1076-6332(03)80212-x

Ntziachristos, V, Bremer C, Tung C, Weissleder R

Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT) Acad Radiol. 2002;9 Suppl 2:S323-5 - PMID: 12188262 - DOI: 10.1016/s1076-6332(03)80217-9

Mahmood U, Weissleder R

Some tools for molecular imaging Acad Radiol. 2002;9:629-31 - PMID: 12061735 - DOI: 10.1016/s1076-6332(03)80306-9

Harisinghani MG, Barentsz JO, Hahn PF, Deserno W, de la Rosette J, Saini S, Marten K, Weissleder R

MR lymphangiography for detection of minimal nodal disease in patients with prostate cancer Acad Radiol. 2002;9 Suppl 2:S312-3 - PMID: 12188258 - DOI: 10.1016/s1076-6332(03)80213-1

Bremer C, Tung CH, Weissleder R

Molecular imaging of MMP expression and therapeutic MMP inhibition Acad Radiol. 2002;9 Suppl 2:S314-5 - PMID: 12188259 - DOI: 10.1016/s1076-6332(03)80214-3

Wagenaar DJ, Weissleder R, Hengerer A

Glossary of molecular imaging terminology Acad Radiol. 2001;8:409-20 - PMID: 11345272 - DOI: 10.1016/S1076-6332(03)80549-4

Bremer C, Weissleder R

In vivo imaging of gene expression Acad Radiol. 2001;8:15-23 - PMID: 11201452 - DOI: 10.1016/s1076-6332(03)80739-0

Harisinghani MG, Saini S, Hahn PF, Weissleder R, Mueller PR

MR imaging of lymph nodes in patients with primary abdominal and pelvic malignancies using ultrasmall superparamagnetic iron oxide (Combidex). Acad Radiol. 1998;5 Suppl 1:S167-9, discussion S183-4 - PMID: 9561072 - DOI: 10.1016/s1076-6332(98)80095-0

Hooper B, Domankevitz Y, Anderson R, Lin CP

Optical temperature probe Appl Phys Lett. 2001;78:2381-3

Lin CP, Kelly MW

Cavitation and acoustic emission around laser-heated microparticles Appl Phys Lett. 1998;72:2800

Hunt TP, Lee H, and Westervelt RM

Addressable micropost array for the dielectrophoretic manipulation of particles in fluid Appl Phys Lett. 0;85(26):6421-23

Lee H, Purdon AM, Westervelt RM

Manipulation of biological cells using a microelectromagnet matrix Appl Phys Lett. 0;85(6):1063-65

Fass DM, Shah R, Ghosh B, Hennig K, Norton S, Zhao WN, Reis SA, Klein PS, Mazitschek R, Maglathlin RL, Lewis TA, Haggarty SJ

Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. ACS Med Chem Lett. 2010;2(1):39-42 - PMID: 21874153 - PMCID: PMC3161516 - DOI: 10.1021/ml1001954

Lesuffleur A, Im H, Lindquist NC, Oh S

Periodic nanohole arrays with shape-enhanced plasmon resonance as real-time biosensors Appl Phys Lett. 2007;90:243110

Vinegoni C, Ralston T, Tan W, Luo W, Marks DL, Boppart SA

Integrated structural and functional imaging combining spectral-domain optical coherence and multiphoton microscopy Appl Phys Lett. 2006;88:051105

Marks DL, Vinegoni C, Bredfeldt JS, Boppart SA

Interferometric differentiation between resonant Coherent Anti-Stokes Raman Scattering and nonresonant four-wave-mixing processes Appl Phys Lett. 2004;85:5787-89

Pellegrini V, Colombelli R, Vinegoni C, Rubini S, Lantier R, Franciosi A, Beltram F, Pavesi L

Second harmonic generation in ZnSe microcavity. Appl. Phys. Lett. 1999;74:1945-47 Appl Phys Lett. 1999;74:1945-47

Cazzanelli M, Cole D, Donegan JF, Lunney JG, Middleton PG, O'Donnell KP, Vinegoni C, Pavesi L

Photoluminescence of localized excitons in pulsed laser deposited GaN Appl Phys Lett. 1998;73:3390-2

Taktak S, Weissleder R, Josephson L

Electrode Chemistry Yields a Nanoparticle-Based NMR Sensor for Calcium. Langmuir. 2008;24 (14):7596-7598 - PMID: 18558729 - PMCID: PMC2748273 - DOI: 10.1021/la8006298

Huang XJ, Ryu SW, Im HS, Choi YK

Wet chemical needlelike assemblies of single-walled carbon nanotubes on a silicon surface. Langmuir. 2007;23(3):991-4 - PMID: 17241002 - DOI: 10.1021/la063144l

Smith RN, Ueno T, Ito T, Tanaka K, Shea SP, Abdi R

Chemokines and chronic heart allograft rejection. Transplantation. 2007;84(3):442-4 - PMID: 17700176 - DOI: 10.1097/01.tp.0000277535.02541.30

Ueno T, Yamada A, Ito T, Yeung MY, Gorbatov R, Shimizu T, Abdi R, Sayegh MH, Auchincloss H, Najafian N

Role of Nuclear Factor of Activated T Cell (NFAT) Transcription Factors in Skin and Vascularized Cardiac Allograft Rejection. Transplantation. 2011;92(5):e26-e27 - PMID: 21866037 - DOI: 10.1097/TP.0b013e318228061c

Tremblay J, Chen H, Peng J, Kunes J, Vu MD, Der Sarkissian S, deBlois D, Bolton AE, Gaboury L, Marshansky V, Gouadon E, Hamet P

Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy. Transplantation. 2002;74(10):1425-33 - PMID: 12451244 - DOI: 10.1097/00007890-200211270-00015

Ansari MJ, Fiorina P, Dada S, Guleria I, Ueno T, Yuan X, Trikudanathan S, Smith RN, Freeman G, Sayegh MH

Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. Clin Immunol. 2007;126(2):140-7 - PMID: 17889619 - DOI: 10.1016/j.clim.2007.07.019

Pirri P, Vinegoni C, Pavesi L

Optical and photoluminescence properties of a-Si(1-x)Nx:H films deposited by PECVD Phys Rev B. 2000;61:4693-8

Giorgis F, Pirri CF, Vinegoni C, Pavesi L

Luminescence processes in amorphous silicon-nitride nanometric multilayers Phys Rev B. 1999;60:11572-76

Nahrendorf M, Weissleder R, Ertl G

Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction? PLoS ONE. 2006;1:e48 - PMID: 17183677 - PMCID: PMC1762326 - DOI: 10.1371/journal.pone.0000048

Kelly KA, Carson J, McCarthy JR, Weissleder R

Novel Peptide Sequence ("IQ-tag") with High Affinity for NIR Fluorochromes Allows Protein and Cell Specific Labeling for In Vivo Imaging. PLoS ONE. 2007;2:e665 - PMID: 17653285 - PMCID: PMC1919420 - DOI: 10.1371/journal.pone.0000665

Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R

A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. PLoS ONE. 2007;2(10):e1075 - PMID: 17957257 - PMCID: PMC2034600 - DOI: 10.1371/journal.pone.0001075

Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Plough HL, Barrett TA, Weissleder R, Khazaie K

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS ONE. 2008;3:e2916 - PMID: 18698347 - PMCID: PMC2488397 - DOI: 10.1371/journal.pone.0002916

Badr C, Hewett J, Breakefield X, Tannous B

A Highly Sensitive Assay for Monitoring the Secretory Pathway and ER Stress PLoS ONE. 0;6:e571

Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L

BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. PLoS ONE. 2008;3(12):e3949 - PMID: 19079609 - PMCID: PMC2597248 - DOI: 10.1371/journal.pone.0003949

Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S

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Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice. Am J Physiol. 1995;269(6 Pt 2):F761-74 - PMID: 8594870 - DOI: 10.1152/ajprenal.1995.269.6.F761

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Inhibition of basolateral potassium conductance by taurine in the proximal convoluted tubule. Am J Physiol. 1996;271(5 Pt 2):F1012-9 - PMID: 8945995 - DOI: 10.1152/ajprenal.1996.271.5.F1012

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Proton secretion in the male reproductive tract: involvement of Cl--independent HCO-3 transport. Am J Physiol. 1998;275(4 Pt 1):C1134-42 - PMID: 9755067 - DOI: 10.1152/ajpcell.1998.275.4.C1134

Emma F, Breton S, Morrison R, Wright S, Strange K

Effect of cell swelling on membrane and cytoplasmic distribution of pICln. Am J Physiol. 1998;274(6 Pt 1):C1545-51 - PMID: 9696697 - DOI: 10.1152/ajpcell.1998.274.6.C1545

Montet X, Rajopadhye M, Weissleder R.

An albumin-activated far-red fluorochrome for in vivo imaging ChemMedChem. 2006;1(1):66-69 - PMID: 16892337 - DOI: 10.1002/cmdc.200500028

Choi YD, McCarthy J, Weissleder R, Tung CH

Conjugation of a Photosensitizer to an Oligoarginine-based Cell-penetrating Peptide Increases the Efficacy of Photodynamic Therapy ChemMedChem. 2006;1(4):458-463 - PMID: 16892381 - DOI: 10.1002/cmdc.200500036

Choi Y, Weissleder R, Tung CH

Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate. ChemMedChem. 2006;1:698-701 - PMID: 16902920 - DOI: 10.1002/cmdc.200600053

McCarthy JR, Weissleder R

Model Systems for Fluorescence and Singlet Oxygen Quenching by Metalloporphyrins. ChemMedChem. 2007;2:360-365 - PMID: 17245681 - DOI: 10.1002/cmdc.200600244

McCarthy JR, Hyland MA, Bruckner C.

Synthesis of indaphyrins: meso-tetraarylsecochlorin-based porphyrinoids containing direct o-phenyl-to-beta-linkages. Org Biomol Chem. 2004;2(10):1484-91

McCarthy JR, Bhaumik J, Merbouh N, Weissleder R

High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins. Org Biomol Chem. 2009;7(17):3430-6 - PMID: 19675897 - PMCID: PMC2749955 - DOI: 10.1039/b908713c

Mazitschek R, Huwe A, Giannis A

Synthesis and biological evaluation of novel fumagillin and ovalicin analogues. Org Biomol Chem. 2005;3(11):2150-4 - PMID: 15917904 - DOI: 10.1039/b503163j

Ueno T, Kaneko K, Katano H, Sato Y, Mazitschek R, Tanaka K, Hattori S, Irie S, Sata T, Ogawa-Goto K

Expansion of the trans-Golgi network following activated collagen secretion is supported by a coiled-coil microtubule-bundling protein, p180, on the ER. Exp Cell Res. 2009;316(3):329-40 - PMID: 19932094 - DOI: 10.1016/j.yexcr.2009.11.009

Pastor-Soler NM, Fisher JS, Sharpe R, Hill E, Van Hoek A, Brown D, Breton S

Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones. Reproduction. 2009;139(3):613-21 - PMID: 19948840 - PMCID: PMC3773695 - DOI: 10.1530/REP-09-0284

Da Silva N, Cortez-Retamozo V, Reinecker HC, Wildgruber M, Hill E, Brown D, Swirski F, Pittet M, Breton S

A dense network of dendritic cells populates the murine epididymis. Reproduction. 2011;141(5):653-63 - PMID: 21310816 - PMCID: PMC3657760 - DOI: 10.1530/REP-10-0493

Reimer P, Bader A, Weissleder R

Application of a stable cell culture assay for the functional assessment of novel MR contrast agents. Eur Radiol. 1997;7(4):527-31 - PMID: 9204333 - DOI: 10.1007/s003300050197

Vinegoni C, Bredfeldt J, Marks D, Boppart S

Nonlinear optical contrast enhancement for optical coherence tomography. Opt Express. 2004;12:331-41 - PMID: 19471542 - DOI: 10.1364/opex.12.000331

Lee H, Alt C, Pitsillides CM, Puoris'haag M, Lin CP

In vivo imaging flow cytometer. Opt Express. 2006;14:7789-800 - PMID: 19529148 - PMCID: PMC2801598 - DOI: 10.1364/oe.14.007789

Tsai CC, Vinegoni C, Weissleder R

Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide. Opt Express. 2009;17(24):21723-31 - PMID: 19997414 - PMCID: PMC2805120 - DOI: 10.1364/OE.17.021723

Vinegoni C, Fexon L, Fumene Feruglio P, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R

High throughput transmission optical projection tomography using low cost graphics processing unit Opt Express. 2009;17(25):22320-22332 - PMID: 20052155 - PMCID: PMC2805020 - DOI: 10.1364/OE.17.022320

Li C, Pastila RK, Pitsillides C, Runnels JM, Puoris'haag M, Cote D, Lin CP

Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence. Opt Express. 2010;18(2):988-99 - PMID: 20173920 - PMCID: PMC3369551 - DOI: 10.1364/OE.18.000988

Razansky RN, Rosenthal A, Mallas G, Razansky D, Jaffer FA, Ntziachristos V

Near-infrared fluorescence catheter system for two-dimensional intravascular imaging in vivo. Opt Express. 2010;18(11):11372-81 - PMID: 20588998 - DOI: 10.1364/OE.18.011372

Mansuripur M, Zakharian AR, Lesuffleur A, Oh SH, Jones RJ, Lindquist NC, Im H, Kobyakov A, Moloney JV

Plasmonic nano-structures for optical data storage. Opt Express. 2009;17(16):14001-14 - PMID: 19654809 - DOI: 10.1364/oe.17.014001

Lesuffleur A, Im H, Lindquist NC, Lim KS, Oh SH

Laser-illuminated nanohole arrays for multiplex plasmonic microarray sensing. Opt Express. 2008;16(1):219-24 - PMID: 18521151 - DOI: 10.1364/oe.16.000219

Curry A, Hwang WL, Wax A

Epi-illumination through the microscope objective applied to darkfield imaging and microspectroscopy of nanoparticle interaction with cells in culture. Opt Express. 2006;14(14):6535-42 - PMID: 19516830 - DOI: 10.1364/oe.14.006535

Salthouse C, Hilderbrand S, Weissleder R, Mahmood U

Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008;16 (26):21731-7 - PMID: 19104605 - PMCID: PMC2717740 - DOI: 10.1364/oe.16.021731

Henry F, Cote D, Randolph M, Rust E, Redmond R, Kochevar I, Lin CP, Winograd J

Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg. 2009;123:123S-30S - PMID: 19182671 - DOI: 10.1097/PRS.0b013e318191c5b8

Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U

Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects. Sens Actuat B-Chem. 2009;138(2):591-597 - PMID: 20161242 - PMCID: PMC2706141 - DOI: 10.1016/j.snb.2009.02.037

Best SR, Peng S, Juang CM, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI

Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery. Vaccine. 2009;27(40):5450-9 - PMID: 19622402 - PMCID: PMC2745985 - DOI: 10.1016/j.vaccine.2009.07.005

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Therapeutic cancer vaccines based on molecularly defined human tumor antigens. Vaccine. 2002;20(4):2-7 - PMID: 12477422 - DOI: 10.1016/s0264-410x(02)00380-8

Bouley R, Hawthorn G, Russo L, Lin H, Ausiello D, Brown D

Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment. Biol Cell. 2006;98(4):215-32 - PMID: 16563128 - DOI: 10.1042/BC20040054

Haller JL, Hyde D, Deliolanis N, de Kleine R, Niedre M, Ntziachristos V

Visualization of Pulmonary Inflammation Using Non-invasive Fluorescence Molecular Imaging. J Appl Physiol. 2008;104(3):795-802 - PMID: 18202169 - DOI: 10.1152/japplphysiol.00959.2007

Cazzanelli M, Vinegoni C, Pavesi L

Temperature dependence of the photo luminescence of all porous silicon microcavities. J. Appl. Phys. 1999;85;1760-4 J Appl Physiol. 1999;85:1760-4

Speiser D, Pittet M, Guillaume P, Lubenow N, Hoffman E, Cerottini J, Romero P

Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring. J Immunother. 2004;27:298-308 - PMID: 15235391 - DOI: 10.1097/00002371-200407000-00006

Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE

Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging. NMR Biomed. 2008;21(5):453-63 - PMID: 17918777 - PMCID: PMC2629945 - DOI: 10.1002/nbm.1209

Framme C, Alt C, Schnell S, Sherwood M, Brinkmann R, Lin CP

Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam. Invest Ophth Vis Sci. 2007;48:1782-92 - PMID: 17389512 - DOI: 10.1167/iovs.06-0797

Wei X, Runnels J, Lin C

Selective uptake of indocyanine green by reticulocytes in circulation. Invest Ophth Vis Sci. 2003;44:4489-96 - PMID: 14507897 - PMCID: PMC2830078 - DOI: 10.1167/iovs.03-0041

Yip S, Shah K

Stem-cell based therapies for brain tumors. Curr Opin Mol Ther. 2008;10:334-42 - PMID: 18683097

Wagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP

Angiotensin II Stimulates H-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts. Cell Physiol Biochem. 2011;28(3):513-20 - PMID: 22116365 - PMCID: PMC3709473 - DOI: 10.1159/000335112

Montes M, Rufer N, Appay V, Reynard S, Pittet M, Speiser D, Guillaume P, Cerottini J, Romero P, Leyvraz S

Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy. Clin Exp Immunol. 2005;142:292-302 - PMID: 16232216 - PMCID: PMC1809512 - DOI: 10.1111/j.1365-2249.2005.02914.x

Ritz S, Cundall M, Gajewska B, Swirski F, Wiley R, Alvarez D, Coyle A, Stampfli M, Jordana M

The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo. Clin Exp Immunol. 2004;138(2):213-20 - PMID: 15498029 - PMCID: PMC1809215 - DOI: 10.1111/j.1365-2249.2004.02618.x

Moffat BA, Reddy GR, McConville P, Hall DE, Chenevert TL, Kopelman RR, Philbert M, Weissleder R, Rehemtulla A, Ross BD

A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI Mol Imaging. 2003;2:324-32 - PMID: 14717331 - DOI: 10.1162/15353500200303163

Lin Y, Weissleder R, Tung CH

Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging Mol Imaging. 2003;2:87-92 - PMID: 12964306 - DOI: 10.1162/15353500200303121

Josephson L, Mahmood U, Wunderbaldinger P, Tang Y, Weissleder R

Pan and sentinel lymph node visualization using a near-infrared fluorescent probe Mol Imaging. 2003;2:18-23 - PMID: 12926234 - DOI: 10.1162/15353500200302154

Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U

Miniaturized multichannel near infrared endoscope for mouse imaging Mol Imaging. 2003;2:350-7 - PMID: 14717334 - DOI: 10.1162/15353500200303166

Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R

Coded aperture nuclear scintigraphy: a novel small animal imaging technique Mol Imaging. 2002;1:344-53 - PMID: 12926230 - DOI: 10.1162/15353500200221362

Schellenberger EA, Bogdanov A Jr, Hogemann D, Tait J, Weissleder R, Josephson L

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Mol Imaging. 2002;1:102-7 - PMID: 12920851 - DOI: 10.1162/15353500200202103

Ntziachristos, V, Bremer C, Graves EE, Ripoll J, Weissleder R

In vivo tomographic imaging of near-infrared fluorescent probes Mol Imaging. 2002;1:82-8 - PMID: 12920848 - DOI: 10.1162/15353500200201121

Kircher MF, Josephson L, Weissleder R

Ratio imaging of enzyme activity using dual wavelength optical reporters Mol Imaging. 2003;1:89-95 - PMID: 12920849 - DOI: 10.1162/15353500200201124

Bogdanov A Jr, Matuszewski L, Bremer C, Petrovsky A, Weissleder R

Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets Mol Imaging. 2002;1:16-23 - PMID: 12920857 - DOI: 10.1162/15353500200200001

Chen WT, Tung CH, Weissleder R

Imaging reactive oxygen species in arthritis. Mol Imaging. 2004;3(3):159-62 - PMID: 15530251 - DOI: 10.1162/15353500200404124

Gillies R, Hoffman J, Lam K, Menkens A, Piwnica-Worms D, Sullivan D, Weissleder R.

Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents Mol Imaging. 2005;4:1-6

Wunder A, Schellenberger E, Mahmood U, Bogdanov A Jr, Muller-Ladner U, Weissleder R, Josephson L.

Methotrexate-induced accumulation of fluorescent annexin v in collagen-induced arthritis Mol Imaging. 2005;4(1):1-6 - PMID: 15967121 - DOI: 10.1162/15353500200504142

Montet-Abou K, Montet X, Weissleder R, Josephson L.

Transfection agent induced nanoparticle cell loading Mol Imaging. 2005;4(3):165-71 - PMID: 16194448 - DOI: 10.1162/15353500200505100

Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R

MIPortal: A High Capacity Server for Molecular Imaging Research. Mol Imaging. 2005;4(4):425-31 - PMID: 16285904 - DOI: 10.2310/7290.2005.05136

Chen WT, Khazaie K, Zhang G, Weissleder R, Tung CH

Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe Mol Imaging. 2005;4 (1):67-74 - PMID: 15912902

Kelly KA, Clemons PA, Yu AM, Weissleder R

High throughput identification of phage-derived imaging agents Mol Imaging. 2006;5(1):24-30 - PMID: 16779967

Sun EY, Josephson L, Weissleder R.

Clickable nanoparticles for targeted imaging Mol Imaging. 2006;(5) 2:122-128 - PMID: 16954026

Jaffer F, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R

Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials Mol Imaging. 2006;(5) 2 :85-92 - PMID: 16954022

Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V

Normalized transillumination of fluorescent proteins in small animals. Mol Imaging. 2006;5 (2):153-9 - PMID: 16954030

Montet-Abou K, Montet X, Weissleder R, Josephson L

Cell internalization of magnetic nanoparticles using transfection agents. Mol Imaging. 2007;(6) 1:1-9 - PMID: 17311760

Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J

Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging. 2007;6(2):96-107 - PMID: 17445504

Sheth RA, Upadhyay R, Weissleder R, Mahmood U

Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007;6(3):147-55 - PMID: 17532881

Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U

Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007;6(4):269-76 - PMID: 17711782

Hiller K, Waller C, Nahrendorf M, Bauer W, Jakob P

Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging. Mol Imaging. 2006;5(2):115-21 - PMID: 16954025

Runnels J, Zamiri P, Spencer J, Veilleux I, Wei X, Bogdanov AA, Lin CP

Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy. Mol Imaging. 2006;5:31-40 - PMID: 16779968 - PMCID: PMC2801601

Wei X, Sipkins D, Pitsillides C, Novak J, Georgakoudi I, Lin C

Real-time detection of circulating apoptotic cells by in vivo flow cytometry. Mol Imaging. 2005;4:415-6 - PMID: 16285902 - PMCID: PMC2801924 - DOI: 10.2310/7290.2005.05148

Kumar A, Chung E, Raymond S, van de Water J, Shah K, Fukumura D, Jain R, Bacskai B, Boas D

Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett. 2009;34(13):2066-8 - PMID: 19572001 - PMCID: PMC2872111 - DOI: 10.1364/ol.34.002066

Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R

Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles Opt Lett. 2009;34(17):2566-8 - PMID: 19724491 - PMCID: PMC2749971 - DOI: 10.1364/OL.34.002566

Novak J, Georgakoudi I, Wei X, Prossin A, Lin C

In vivo flow cytometer for real-time detection and quantification of circulating cells. Opt Lett. 2004;29:77-9 - PMID: 14719666 - PMCID: PMC2801600 - DOI: 10.1364/ol.29.000077

Lin C, Webb R

Fiber-coupled multiplexed confocal microscope. Opt Lett. 2000;25:954-6 - PMID: 18064238 - DOI: 10.1364/ol.25.000954

Swanson EA, Izatt JA, Hee MR, Huang D, Lin CP, Schuman JS, Puliafito CA, Fujimoto JG

In vivo retinal imaging by optical coherence tomography. Opt Lett. 1993;18(21):1864-6 - PMID: 19829430 - DOI: 10.1364/ol.18.001864

Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R

Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography. Opt Lett. 2010;35(7):1088-90 - PMID: 20364226 - PMCID: PMC2900933 - DOI: 10.1364/OL.35.001088

Ntziachristos V, Weissleder R

Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Opt Lett. 2001;26(12):893-5 - PMID: 18040483 - DOI: 10.1364/ol.26.000893

Ntziachristos V, Ripoll J, Weissleder R

Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Errata. Opt Lett. 2002;27(18):1652 - PMID: 18026531 - DOI: 10.1364/ol.27.001652

Ripoll J, Nieto-Vesperinas M, Weissleder R, Ntziachristos V

Fast analytical approximation for arbitrary geometries in diffuse optical tomography. Opt Lett. 2002;27(7):527-9 - PMID: 18007854 - DOI: 10.1364/ol.27.000527

Ntziachristos V, Ripoll J, Weissleder R

Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Opt Lett. 2002;27(5):333-5 - PMID: 18007794 - DOI: 10.1364/ol.27.000333

Turner GM, Zacharakis G, Soubret A, Ripoll J, Ntziachristos V.

Complete-angle projection diffuse optical tomography by use of early photons Opt Lett. 2005;30(4):409-11 - PMID: 15762444 - DOI: 10.1364/ol.30.000409

Deliolanis N, Lasser T, Hyde D, Soubret A, Ripoll J, Ntziachristos V

Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections. Opt Lett. 2007;32(4):382-4 - PMID: 17356660 - DOI: 10.1364/ol.32.000382

Razansky D, Vinegoni C, Ntziachristos V

Multispectral photoacoustic imaging of fluorochromes in small animals. Opt Lett. 2007;32(19):2891-3 - PMID: 17909608 - DOI: 10.1364/ol.32.002891

Alt C, Veilleux I, Lee H, Pitsillides CM, Cote D, Lin CP

Retinal flow cytometer. Opt Lett. 2007;32:3450-2 - PMID: 18059963 - PMCID: PMC2794483 - DOI: 10.1364/ol.32.003450

Biss DP, Sumorok D, Burns SA, Webb RH, Zhou Y, Bifano TG, Cote D, Veilleux I, Zamiri P, Lin CP

In vivo fluorescent imaging of the mouse retina using adaptive optics. Opt Lett. 2007;32:659-61 - PMID: 17308593 - PMCID: PMC2808135 - DOI: 10.1364/ol.32.000659

Razansky D, Vinegoni C, Ntziachristos V

Polarization-sensitive optoacoustic tomography of optically diffuse tissues. Opt Lett. 2008;33(20):2308-10 - PMID: 18923605 - DOI: 10.1364/ol.33.002308

Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R

Normalized Born ratio for fluorescence optical projection tomography. Opt Lett. 2009;34(3):319-21 - PMID: 19183644 - PMCID: PMC2771918 - DOI: 10.1364/ol.34.000319

Jones G, Marks D, Vinegoni C, Boppart S

High-spectral-resolution coherent anti-Stokes Raman scattering with interferometrically detected broadband chirped pulses. Opt Lett. 2006;31(10):1543-5 - PMID: 16642166 - DOI: 10.1364/ol.31.001543

Xu C, Vinegoni C, Ralston T, Luo W, Tan W, Boppart S

Spectroscopic spectral-domain optical coherence microscopy. Opt Lett. 2006;31:1079-81 - PMID: 16625909 - DOI: 10.1364/ol.31.001079

Nahrendorf M, Hiller KH, Hu K, Zeijlemaker V, Griswold M, Bauer WR

Pacing in high field cardiac magnetic resonance imaging:. Pacing Clin Electrophysiol. 2004;27(5):671-4 - PMID: 15125728 - DOI: 10.1111/j.1540-8159.2004.00506.x

Veilleux I, Spencer JA, Biss DP, C

In vivo cell tracking with video rate multimodality laser scanning microscopy IEEE J Sel Top Quant. 2008;14:10:18

Lin CP, Kelly MW, Sibayan SA, Latina MA, Anderson RR

Selective Cell Killing by Microparticle Absorption of Pulsed Laser Radiation IEEE J Sel Top Quant. 1999;5:963-8

Rigosi E, Frasnelli E, Vinegoni C, Antolini R, Anfora G, Vallortigara G, Haase A

Searching for anatomical correlates of olfactory lateralization in the honeybee antennal lobes: A morphological and behavioural study. Behav Brain Res.. 2011;221(1):290-4 - PMID: 21402106 - PMCID: PMC3089663 - DOI: 10.1016/j.bbr.2011.03.015

Allport JR, Shinde Patil VR, Weissleder R

Murine Neuronal Progenitor Cells are Preferentially Recruited to Tumor Vasculature via alpha(4)-integrin and SDF-1alpha-Dependent Mechanisms. Cancer Biol Ther. 2004;3(9):838-44 - PMID: 15254391 - DOI: 10.4161/cbt.3.9.1036

Shah K.

Current Advances in Molecular Imaging of Gene and Cell Therapy for Cancer Cancer Biol Ther. 2005;4(5):518-523 - PMID: 15908803 - DOI: 10.4161/cbt.4.5.1706

Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel D, Grant S, Fisher P

Searching for a cure: Gene therapy for glioblastoma. Cancer Biol Ther. 2008;7(9):1335-40 - PMID: 18708757 - DOI: 10.4161/cbt.7.9.6408

Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus W, Ramakrishnan V, Sarkar D, Shah K, Curiel D, Grant S, Fisher P, Dent P

MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biol Ther. 2008;7:917-33 - PMID: 18376144 - DOI: 10.4161/cbt.7.6.5928

Wunderbaldinger P, Josephson L, Bremer C, Moore A, Weissleder R

Detection of lymph node metastases by contrast-enhanced MRI in an experimental model Magn Reson Med. 2002;47:292-7 - PMID: 11810672 - DOI: 10.1002/mrm.10068

Moore, A, Sun PZ, Cory D, Hogemann D, Weissleder R, Lipes MA

MRI of insulitis in autoimmune diabetes Magn Reson Med. 2002;47:751-8 - PMID: 11948737 - DOI: 10.1002/mrm.10110

Kim YR, Savellano MD, Savellano DH, Weissleder R, Bogdanov A Jr

Measurement of tumor interstitial volume fraction: Method and implication for drug delivery Magn Reson Med. 2004;52(3):485-94 - PMID: 15334566 - DOI: 10.1002/mrm.20182

Chen JW, Pham W, Weissleder R, Bogdanov A Jr

Human myeloperoxidase: A potential target for molecular MR imaging in atherosclerosis. Magn Reson Med. 2004;52(5):1021-8 - PMID: 15508166 - DOI: 10.1002/mrm.20270

Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L.

Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle Magn Reson Med. 2005;54(3):718-724 - PMID: 16086367 - DOI: 10.1002/mrm.20617

Hong R, Cima MJ, Weissleder R, Josephson L

Magnetic microparticle aggregation for viscosity determination by MR. Magn Reson Med. 2008;59:515-520 - PMID: 18306403 - PMCID: PMC2740908 - DOI: 10.1002/mrm.21526

Schmitt M, Potthast A, Sosnovik DE, Polimeni JR, Wiggins GC, Triantafyllou C, Wald LL

A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla. Magn Reson Med. 2008;59:1431-1439 - PMID: 18506789 - PMCID: PMC2548273 - DOI: 10.1002/mrm.21598

Streif J, Nahrendorf M, Hiller K, Waller C, Wiesmann F, Rommel E, Haase A, Bauer W

In vivo assessment of absolute perfusion and intracapillary blood volume in the murine myocardium by spin labeling magnetic resonance imaging. Magn Reson Med. 2005;53(3):584-92 - PMID: 15723416 - DOI: 10.1002/mrm.20327

Vonken EJ, Korosoglou G, Yu J, Schar M, Weissleder R, Stuber M

On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA). Magn Reson Med. 2009;62(2):314-24 - PMID: 19526511 - PMCID: PMC2742771 - DOI: 10.1002/mrm.22027

Zaharchuk G, Bogdanov AA, Marota JJ, Shimizu-Sasamata M, Weisskoff RM, Kwong KK, Jenkins BG, Weissleder R, Rosen BR

Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): a steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction. Magn Reson Med. 1998;40(5):666-78 - PMID: 9797148 - DOI: 10.1002/mrm.1910400504

Mandeville JB, Marota JJ, Kosofsky BE, Keltner JR, Weissleder R, Rosen BR, Weisskoff RM

Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med. 1998;39(4):615-24 - PMID: 9543424 - DOI: 10.1002/mrm.1910390415

Mandeville JB, Moore J, Chesler DA, Garrido L, Weissleder R, Weisskoff RM

Dynamic liver imaging with iron oxide agents: effects of size and biodistribution on contrast. Magn Reson Med. 1997;37(6):885-90 - PMID: 9178240 - DOI: 10.1002/mrm.1910370613

Harika L, Weissleder R, Poss K, Zimmer C, Papisov MI, Brady TJ

MR lymphography with a lymphotropic T1-type MR contrast agent: Gd-DTPA-PGM. Magn Reson Med. 1995;33(1):88-92 - PMID: 7891541 - DOI: 10.1002/mrm.1910330113

Shen T, Weissleder R, Papisov M, Bogdanov A, Brady TJ

Monocrystalline iron oxide nanocompounds (MION): physicochemical properties. Magn Reson Med. 1993;29(5):599-604 - PMID: 8505895 - DOI: 10.1002/mrm.1910290504

Weissleder R

Target-specific superparamagnetic MR contrast agents. Magn Reson Med. 1991;22(2):209-12; discussion 213-5 - PMID: 1812348 - DOI: 10.1002/mrm.1910220209

Streif JU, Herold V, Szimtenings M, Lanz TE, Nahrendorf M, Wiesmann F, Rommel E, Haase A

In vivo time-resolved quantitative motion mapping of the murine myocardium with phase contrast MRI. Magn Reson Med. 2003;49(2):315-21 - PMID: 12541252 - DOI: 10.1002/mrm.10342

Brown D, Paunescu TG, Breton S, Marshansky V

Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking. J Exp Biol. 2009;212(Pt 11):1762-72 - PMID: 19448085 - PMCID: PMC2683016 - DOI: 10.1242/jeb.028803

Shum WW, Da Silva N, Brown D, Breton S

Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk. J Exp Biol. 2009;212(Pt 11):1753-61 - PMID: 19448084 - PMCID: PMC2683015 - DOI: 10.1242/jeb.027284

Brown D, Breton S

Mitochondria-rich, proton-secreting epithelial cells. J Exp Biol. 1996;199(Pt 11):2345-58 - PMID: 9114500 - DOI: 10.1242/jeb.199.11.2345

Brown D, Smith PJ, Breton S

Role of V-ATPase-rich cells in acidification of the male reproductive tract. J Exp Biol. 1997;200(Pt 2):257-62 - PMID: 9050233 - DOI: 10.1242/jeb.200.2.257

Brown D, Breton S

H(+)V-ATPase-dependent luminal acidification in the kidney collecting duct and the epididymis/vas deferens: vesicle recycling and transcytotic pathways. J Exp Biol. 2000;203(Pt 1):137-45 - PMID: 10600682 - DOI: 10.1242/jeb.203.1.137

Reiner T, Earley S, Turetsky A, Weissleder R

Bioorthogonal Small-Molecule Ligands for PARP1 Imaging in Living Cells. Chembiochem. 2010;11(17):2374-2377 - PMID: 20967817 - PMCID: PMC3034378 - DOI: 10.1002/cbic.201000477

Addicks E, Mazitschek R, Giannis A

Synthesis and biological investigation of novel tricyclic benzodiazepinedione-based RGD analogues. Chembiochem. 2002;3(11):1078-88 - PMID: 12404633 - DOI: 10.1002/1439-7633(20021104)3:11<1078::AID-CBIC1078>3.0.CO;2-2

Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R

Novel Factor XIII Probes for Blood Coagulation Imaging Chembiochem. 2003;4:897-899 - PMID: 12964167 - DOI: 10.1002/cbic.200300602

Tung CH, Gerszten RE, Jaffer FA, Weissleder R

A novel near-infrared fluorescence sensor for detection of thrombin activation in blood Chembiochem. 2002;3:207-11 - PMID: 11921399 - DOI: 10.1002/1439-7633(20020301)3:2/3<207::AID-CBIC207>3.0.CO;2-B

Tung CH, Lin Y, Moon WK, Weissleder R

A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging Chembiochem. 2002;3:784-6 - PMID: 12203978 - DOI: 10.1002/1439-7633(20020802)3:8<784::AID-CBIC784>3.0.CO;2-X

Perez JM, Josephson L, Weissleder R

Use of magnetic nanoparticles as nanosensors to probe for molecular interactions Chembiochem. 2004;5:261-4 - PMID: 14997516 - DOI: 10.1002/cbic.200300730

Schellenberger EA, Reynolds F, Weissleder R, Josephson L

Surface-functionalized nanoparticle library yields probes for apoptotic cells Chembiochem. 2004;5:275-9 - PMID: 14997519 - DOI: 10.1002/cbic.200300713

Schellenberger EA, Weissleder R, Josephson L

Optimal modification of annexin v with fluorescent dyes Chembiochem. 2004;5:271-4 - PMID: 14997518 - DOI: 10.1002/cbic.200300741

Pham W, Kircher MF, Weissleder R, Tung CH

Enhancing membrane permeability by Fatty acylation of oligoarginine peptides. Chembiochem. 2004;5(8):1148-51 - PMID: 15300843 - DOI: 10.1002/cbic.200400063

Koch AM, Reynolds F, Merkle HP, Weissleder R, Josephson L.

Transport Of Surface-Modified Nanoparticles Through Cell Monolayers Chembiochem. 2005;6(2):337-345 - PMID: 15651046 - DOI: 10.1002/cbic.200400174

Law B, Weissleder R, Tung CH.

Mechanism-Based Fluorescent Reporter for Protein Kinase A Detection Chembiochem. 2005;6(8):1361-1367 - PMID: 16010698 - DOI: 10.1002/cbic.200500027

Ho NH, Weissleder R, Tung CH

A Self-Immolative Reporter For beta-Galactosidase Sensing. Chembiochem. 2007;8:560-566 - PMID: 17300128 - DOI: 10.1002/cbic.200600386

Haase A, Rigosi E, Trona F, Anfora G, Vallortigara G, Antolini R, Vinegoni C

In-vivo two-photon imaging of the honey bee antennal lobe. Biomed Opt Express. 2010;2(1):131-8 - PMID: 21326643 - PMCID: PMC3028488 - DOI: 10.1364/BOE.1.000131

Deliolanis NC, Wurdinger T, Pike L, Tannous BA, Breakefield XO, Weissleder R, Ntziachristos V

In vivo tomographic imaging of red-shifted fluorescent proteins. Biomed Opt Express. 2011;2(4):887-900 - PMID: 21483611 - PMCID: PMC3072128 - DOI: 10.1364/BOE.2.000887

Bélanger E, Henry FP, Vallée R, Randolph MA, Kochevar IE, Winograd JM, Lin CP, Côté D

In vivo evaluation of demyelination and remyelination in a nerve crush injury model. Biomed Opt Express. 2011;2(9):2698-2708 - PMID: 22091449 - PMCID: PMC3184878 - DOI: 10.1364/BOE.2.002698

Remsen LG, McCormick CI, Roman-Goldstein S, Nilaver G, Weissleder R, Bogdanov A, Hellström I, Kroll RA, Neuwelt EA

MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis. AJNR Am J Neuroradiol. 1996;17(3):411-8 - PMID: 8881233 - PMCID: PMC8337991

Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N

Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006;105:445-54 - PMID: 16961141 - DOI: 10.3171/jns.2006.105.3.445

J.W. Chen, R.L. Belford, R.B. Clarkson

Second-Sphere and Outer-Sphere Proton Relaxation of Paramagnetic Contrast Agents J Phys Chem B. 1998;102:2117-2130

J.W. Chen, R.B. Clarkson, R.L. Belford

Rotational Dynamics of MRI Paramagnetic Contrast Agents in Viscous Media J Phys Chem B. 1996;100:8093-8100

J.W. Chen, F.P. Auteri, D.E. Budil, R.L. Belford, R.B. Clarkson

Use of EPR to Investigate Rotational Dynamics of MRI Paramagnetic Contrast Agents J Phys Chem B. 1994;98:13452

Huang XJ, Im HS, Yarimaga O, Kim JH, Lee DH, Kim HS, Choi YK

Direct electrochemistry of uric acid at chemically assembled carboxylated single-walled carbon nanotubes netlike electrode. J Phys Chem B. 2006;110(43):21850-6 - PMID: 17064150 - DOI: 10.1021/jp063749q

Carney BJ, Shah K

Migration and fate of therapeutic stem cells in different brain disease models. Neuroscience. 2011;197:37-47 - PMID: 21946010 - PMCID: PMC3589128 - DOI: 10.1016/j.neuroscience.2011.08.063

Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS

Genetically engineered T cells to target EGFRvIII expressing glioblastoma. J Neuro-Oncol. 2009;94(3):373-82 - PMID: 19387557 - PMCID: PMC2730985 - DOI: 10.1007/s11060-009-9889-1

Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM

RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport. Mol Biol Cell. 2000;11(9):3155-68 - PMID: 10982407 - PMCID: PMC14982 - DOI: 10.1091/mbc.11.9.3155

Cabrero JR, Serrador JM, Barreiro O, Mittelbrunn M, Naranjo-Suárez S, Martín-Cófreces N, Vicente-Manzanares M, Mazitschek R, Bradner JE, Avila J, Valenzuela-Fernández A, Sánchez-Madrid F

Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell. 2006;17(8):3435-45 - PMID: 16738306 - PMCID: PMC1525231 - DOI: 10.1091/mbc.E06-01-0008

Celso CL, Wu JW, Lin CP

In vivo imaging of hematopoietic stem cells and their microenvironment. J Biophotonics. 2009;2(11):619-631 - PMID: 19847800 - DOI: 10.1002/jbio.200910072

Estiu G, West N, Mazitschek R, Greenberg E, Bradner JE, Wiest O

On the inhibition of histone deacetylase 8. Bioorg Med Chem. 2010;18(11):4103-4110 - PMID: 20472442 - PMCID: PMC3245874 - DOI: 10.1016/j.bmc.2010.03.080

Tung CH, Mueller S, Weissleder R

Novel branching membrane translocational peptide as gene delivery vector Bioorg Med Chem. 2002;10:3609-14 - PMID: 12213476 - DOI: 10.1016/s0968-0896(02)00248-1

Ho NH, Weissleder R, Tung CH

Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate. Bioorg Med Chem. 2006;16:2599-2602 - PMID: 16517162 - DOI: 10.1016/j.bmcl.2006.02.045

Sun N, Liu Y, Lee H, Weissleder R, Ham D

CMOS RF Biosensor Utilizing Nuclear Magnetic Resonance IEEE J Solid-ST Circ. 2009;44:1629-1643

Sun N, Yoon TJ, Lee H, Andress W, Weissleder R, Ham D

Palm NMR and 1-Chip NMR IEEE J Solid-ST Circ. 2011;46(1):342-352

Goergen CJ, Sosnovik DE

From Molecules to Myofibers: Multiscale Imaging of the Myocardium. J Cardiovasc Transl Res. 2011;4(4):493-503 - PMID: 21643889 - PMCID: PMC3370890 - DOI: 10.1007/s12265-011-9284-0

Jayasena V, Brown D, Shtatland T, Gold L

In vitro selection of RNA specifically cleaved by bacteriophage T4 RegB endonuclease. Biochemistry-US. 1996;35:2349-56 - PMID: 8652576 - DOI: 10.1021/bi951879b

Senior S, Mans L, VanGuilder H, Kelly K, Hendrich M, Elgren T

Catecholase activity associated with copper-S100B. Biochemistry-US. 2003;42:4392-7 - PMID: 12693934 - DOI: 10.1021/bi0205799

Elgren T, Orville A, Kelly K, Lipscomb J, Ohlendorf D, Que L

Crystal structure and resonance Raman studies of protocatechuate 3,4-dioxygenase complexed with 3,4-dihydroxyphenylacetate. Biochemistry-US. 1997;36:11504-13 - PMID: 9298971 - DOI: 10.1021/bi970691k

Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP

Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model. Pancreas. 2008;37(4):440-4 - PMID: 18953259 - PMCID: PMC3806135 - DOI: 10.1097/MPA.0b013e31817c5113

Spear MA, Breakefield XO, Beltzer J, Schuback D, Weissleder R, Pardo FS, Ladner R

Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells Cancer Gene Ther. 2001;8:506-11 - PMID: 11498772 - DOI: 10.1038/sj.cgt.7700334

Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U

In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008;1:84-94 - PMID: 18633456 - PMCID: PMC2510813 - DOI: 10.1593/tlo.08118

Moore A, Marecos E, Simonova M, Weissleder R, Bogdanov A

Novel gliosarcoma cell line expressing green fluorescent protein: A model for quantitative assessment of angiogenesis. Microvasc Res. 1998;56(3):145-53 - PMID: 9828152 - DOI: 10.1006/mvre.1998.2102

Waller C, Hiller KH, Albrecht M, Hu K, Nahrendorf M, Gattenl

Microvascular adaptation to coronary stenosis in the rat heart in vivo: a serial magnetic resonance imaging study. Microvasc Res. 2003;66(3):173-82 - PMID: 14609522 - DOI: 10.1016/s0026-2862(03)00058-x

Graves EE, Ripoll J, Weissleder R, Ntziachristos V

A submillimeter resolution fluorescence molecular imaging system for small animal imaging Med Phys. 2003;30:901-11 - PMID: 12772999 - DOI: 10.1118/1.1568977

Ntziachristos V, Weissleder R

Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media Med Phys. 2002;29:803-9 - PMID: 12033576 - DOI: 10.1118/1.1470209

Turner GM, Soubret A, Ntziachristos V

Inversion with early photons. Med Phys. 2007;34(4):1405-11 - PMID: 17500472 - DOI: 10.1118/1.2437103

Razansky D, Ntziachristos V

Hybrid photoacoustic fluorescence molecular tomography using finite-element-based inversion. Med Phys. 2007;34(11):4293-301 - PMID: 18072494 - DOI: 10.1118/1.2786866

Allport JR, Weissleder R

In vivo imaging of gene and cell therapies Exp Hematol. 2001;29:1237-46 - PMID: 11698119 - DOI: 10.1016/s0301-472x(01)00739-1

Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M

Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells. Exp Hematol. 2010;38(4):333-9 - PMID: 20167247 - PMCID: PMC3965294 - DOI: 10.1016/j.exphem.2010.02.003

Pandharipande PV, Mora JT, Uppot RN, Goehler A, Braschi M, Halpern EF, Gazelle GS, Harisinghani MG

Lymphotropic nanoparticle-enhanced MRI for independent prediction of lymph node malignancy: a logistic regression model. AJR Am J Roentgenol. 2009;193(3):W230-7 - PMID: 19696264 - DOI: 10.2214/AJR.08.2175

Baier ND, Hahn PF, Gervais DA, Samir A, Halpern EF, Mueller PR, Harisinghani MG

Fine-needle aspiration biopsy of thyroid nodules: experience in a cohort of 944 patients. AJR Am J Roentgenol. 2009;193(4):1175-9 - PMID: 19770344 - DOI: 10.2214/AJR.08.1840

Gee MS, Kim JY, Gervais DA, Hahn PF, Mueller PR

Management of abdominal and pelvic abscesses that persist despite satisfactory percutaneous drainage catheter placement. AJR Am J Roentgenol. 2010;194(3):815-20 - PMID: 20173165 - DOI: 10.2214/AJR.09.3282

Uppot RN, Harisinghani MG, Gervais DA

Imaging-guided percutaneous renal biopsy: rationale and approach. AJR Am J Roentgenol. 2010;194(6):1443-9 - PMID: 20489082 - DOI: 10.2214/AJR.10.4427

Sena BF, Stern JP, Pandharipande PV, Klemm B, Bulman J, Pedrosa I, Rofsky NM

Screening patients to assess renal function before administering gadolinium chelates: assessment of the choyke questionnaire. AJR Am J Roentgenol. 2010;195(2):424-8 - PMID: 20651199 - PMCID: PMC6247784 - DOI: 10.2214/AJR.09.3803

Cronin CG, Harisinghani MG, Catalano O, Blake MA

Multitechnique imaging findings of prolene plug hernia repair. AJR Am J Roentgenol. 2010;195(3):701-6 - PMID: 20729449 - DOI: 10.2214/AJR.09.4142

Callahan RJ, Bogdanov A, Fischman AJ, Brady TJ, Weissleder R

Preclinical evaluation and phase I clinical trial of a 99mTc-labeled synthetic polymer used in blood pool imaging. AJR Am J Roentgenol. 1998;171(1):137-43 - PMID: 9648777 - DOI: 10.2214/ajr.171.1.9648777

Weissleder R

Can gadolinium be safely given in renal failure? AJR Am J Roentgenol. 1996;167(1):278-9 - PMID: 8659405 - DOI: 10.2214/ajr.167.1.8659405

Lu DS, Saini S, Hahn PF, Goldberg M, Lee MJ, Weissleder R, Gerard B, Halpern E, Cats A

T2-weighted MR imaging of the upper part of the abdomen: should fat suppression be used routinely? AJR Am J Roentgenol. 1994;162(5):1095-100 - PMID: 8165989 - DOI: 10.2214/ajr.162.5.8165989

Frank H, Weissleder R, Bogdanov AA, Brady TJ

Detection of pulmonary emboli by using MR angiography with MPEG-PL-GdDTPA: an experimental study in rabbits. AJR Am J Roentgenol. 1994;162(5):1041-6 - PMID: 8165978 - DOI: 10.2214/ajr.162.5.8165978

Frank H, Weissleder R, Brady TJ

Enhancement of MR angiography with iron oxide: preliminary studies in whole-blood phantom and in animals. AJR Am J Roentgenol. 1994;162(1):209-13 - PMID: 8273667 - DOI: 10.2214/ajr.162.1.8273667

Chew FS, Weissleder R

Radiation-induced osteochondroma. AJR Am J Roentgenol. 1991;157(4):792 - PMID: 1892038 - DOI: 10.2214/ajr.157.4.1892038

Chew FS, Weissleder R

Mediastinal thymolipoma. AJR Am J Roentgenol. 1991;157(3):468 - PMID: 1872228 - DOI: 10.2214/ajr.157.3.1872228

Weissleder R, Reimer P, Lee AS, Wittenberg J, Brady TJ

MR receptor imaging: ultrasmall iron oxide particles targeted to asialoglycoprotein receptors. AJR Am J Roentgenol. 1990;155(6):1161-7 - PMID: 2122660 - DOI: 10.2214/ajr.155.6.2122660

Fretz CJ, Stark DD, Metz CE, Elizondo G, Weissleder R, Shen JH, Wittenberg J, Simeone J, Ferrucci JT

Detection of hepatic metastases: comparison of contrast-enhanced CT, unenhanced MR imaging, and iron oxide-enhanced MR imaging. AJR Am J Roentgenol. 1990;155(4):763-70 - PMID: 2119106 - DOI: 10.2214/ajr.155.4.2119106

Hahn PF, Stark DD, Saini S, Rummeny E, Elizondo G, Weissleder R, Wittenberg J, Ferrucci JT

The differential diagnosis of ringed hepatic lesions in MR imaging. AJR Am J Roentgenol. 1990;154(2):287-90 - PMID: 2153330 - DOI: 10.2214/ajr.154.2.2153330

Rummeny E, Saini S, Stark DD, Weissleder R, Compton CC, Ferrucci JT

Detection of hepatic metastases with MR imaging: spin-echo vs phase-contrast pulse sequences at 0.6 T. AJR Am J Roentgenol. 1989;153(6):1207-11 - PMID: 2683677 - DOI: 10.2214/ajr.153.6.1207

Rummeny E, Saini S, Wittenberg J, Compton C, Hahn PF, Mueller PR, Simeone JF, Stark DD, Weissleder R, Dousset MG

MR imaging of liver neoplasms. AJR Am J Roentgenol. 1989;152(3):493-9 - PMID: 2536996 - DOI: 10.2214/ajr.152.3.493

Weissleder R, Elizondo G, Stark DD, Hahn PF, Marfil J, Gonzalez JF, Saini S, Todd LE, Ferrucci JT

The diagnosis of splenic lymphoma by MR imaging: value of superparamagnetic iron oxide. AJR Am J Roentgenol. 1989;152(1):175-80 - PMID: 2783273 - DOI: 10.2214/ajr.152.1.175

Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, White DL, Jacobs P, Lewis J

Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol. 1989;152(1):167-73 - PMID: 2783272 - DOI: 10.2214/ajr.152.1.167

Rummeny E, Weissleder R, Stark DD, Saini S, Compton CC, Bennett W, Hahn PF, Wittenberg J, Malt RA, Ferrucci JT

Primary liver tumors: diagnosis by MR imaging. AJR Am J Roentgenol. 1989;152(1):63-72 - PMID: 2535770 - DOI: 10.2214/ajr.152.1.63

Wittenberg J, Stark DD, Forman BH, Hahn PF, Saini S, Weissleder R, Rummeny E, Ferrucci JT

Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR Am J Roentgenol. 1988;151(1):79-84 - PMID: 3259825 - DOI: 10.2214/ajr.151.1.79

Hahn PF, Weissleder R, Stark DD, Saini S, Elizondo G, Ferrucci JT

MR imaging of focal splenic tumors. AJR Am J Roentgenol. 1988;150(4):823-7 - PMID: 3279735 - DOI: 10.2214/ajr.150.4.823

Weissleder R, Saini S, Stark DD, Wittenberg J, Ferrucci JT

Dual-contrast MR imaging of liver cancer in rats. AJR Am J Roentgenol. 1988;150(3):561-6 - PMID: 3257610 - DOI: 10.2214/ajr.150.3.561

Weissleder R, Hahn PF, Stark DD, Rummeny E, Saini S, Wittenberg J, Ferrucci JT

MR imaging of splenic metastases: ferrite-enhanced detection in rats. AJR Am J Roentgenol. 1987;149(4):723-6 - PMID: 3498320 - DOI: 10.2214/ajr.149.4.723

Cronin CG, Gervais DA, Hahn PF, Arellano R, Guimaraes AR, Mueller PR

Treatment of Deep Intramuscular and Musculoskeletal Abscess: Experience With 99 CT-Guided Percutaneous Catheter Drainage Procedures. AJR Am J Roentgenol. 2011;196(5):1182-1188 - PMID: 21512090 - DOI: 10.2214/AJR.09.4082

Gee MS, Nimkin K, Hsu M, Israel EJ, Biller JA, Katz AJ, Mino-Kenudson M, Harisinghani MG

Prospective Evaluation of MR Enterography as the Primary Imaging Modality for Pediatric Crohn Disease Assessment. AJR Am J Roentgenol. 2011;197(1):224-31 - PMID: 21701034 - PMCID: PMC3711021 - DOI: 10.2214/AJR.10.5970

O'Neill MJ, Weissleder R, Gervais DA, Hahn PF, Mueller PR

Tunneled peritoneal catheter placement under sonographic and fluoroscopic guidance in the palliative treatment of malignant ascites AJR Am J Roentgenol. 2001;177:615-8 - PMID: 11517056 - DOI: 10.2214/ajr.177.3.1770615

Harisinghani MG, Saini S, Weissleder R, Hahn PF, Yantiss RK, Tempany C, Wood BJ, Mueller PR

MR lymphangiography using ultrasmall superparamagnetic iron oxide in patients with primary abdominal and pelvic malignancies: radiographic-pathologic correlation AJR Am J Roentgenol. 1999;172:1347-51 - PMID: 10227514 - DOI: 10.2214/ajr.172.5.10227514

Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, Weissleder R

Ferumoxtran-10-Enhanced MR Lymphangiography: Does Contrast-Enhanced Imaging Alone Suffice for Accurate Lymph Node Characterization? AJR Am J Roentgenol. 2006;186(1):144-8 - PMID: 16357394 - DOI: 10.2214/AJR.04.1287

Saksena M, Harisinghani M, Hahn P, Kim J, Saokar A, King B, Weissleder R

Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers. AJR Am J Roentgenol. 2006;187(6):W582-8 - PMID: 17114509 - DOI: 10.2214/AJR.05.0873

Goldberg M, Pivovarov M, Mayo-Smith W, Bhalla M, Blickman J, Bramson R, Boland G, Llewellyn H, Halpern E

Application of wavelet compression to digitized radiographs. AJR Am J Roentgenol. 1994;163:463-8 - PMID: 8037051 - DOI: 10.2214/ajr.163.2.8037051

Pandharipande PV, Harisinghani MG, Ozanne EM, Specht MC, Hur C, Lee JM, Gazelle GS

Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis. AJR Am J Roentgenol. 2008;191:1308-19 - PMID: 18941062 - DOI: 10.2214/AJR.07.3861

Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V.

Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography J Biomed Opt. 2005;10(4):44019 - PMID: 16178652 - DOI: 10.1117/1.1993427

Ntziachristos V, Turner G, Dunham J, Windsor S, Soubret A, Ripoll J, Shih HA

Planar fluorescence imaging using normalized data. J Biomed Opt. 2005;10(6):64007 - PMID: 16409072 - DOI: 10.1117/1.2136148

Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA

Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy. J Biomed Opt. 2006;11(2):21009 - PMID: 16674184 - DOI: 10.1117/1.2186337

Hsiao JK, Law B, Weissleder R, Tung CH

In-vivo imaging of tumor associated urokinase-type plasminogen activator activity. J Biomed Opt. 2006;11(3):34013 - PMID: 16822063 - DOI: 10.1117/1.2204029

Niedre MJ, Turner GM, Ntziachristos V

Time-resolved imaging of optical coefficients through murine chest cavities. J Biomed Opt. 2006;11(6):064017 - PMID: 17212540 - DOI: 10.1117/1.2400702

Kim P, Puoris'haag M, Cote D, Lin CP, Yun SH

In vivo confocal and multiphoton microendoscopy. J Biomed Opt. 2008;13(1):010501 - PMID: 18315346 - PMCID: PMC2752311 - DOI: 10.1117/1.2839043

Deliolanis NC, Kasmieh R, Wurdinger T, Tannous BA, Shah K, Ntziachristos V

Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications. J Biomed Opt. 2008;13(4):044008 - PMID: 19021336 - PMCID: PMC2749214 - DOI: 10.1117/1.2967184

Deliolanis N, Dunham J, Wurdinger T, Figueiredo J, Bakhos T, Ntziachristos V

In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography. J Biomed Opt. 2009;14(3):030509 - PMID: 19566290 - PMCID: PMC2881930 - DOI: 10.1117/1.3149854

Lee H, Alt C, Pitsillides C, Lin CP

Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration. J Biomed Opt. 2007;12:064034 - PMID: 18163850 - DOI: 10.1117/1.2804078

Boutrus S, Greiner C, Hwu D, Chan M, Kuperwasser C, Lin CP, Georgakoudi I

Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells. J Biomed Opt. 2007;12:020507 - PMID: 17477705 - PMCID: PMC2798734 - DOI: 10.1117/1.2722733

Roegener J, Brinkmann R, Lin CP

Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells. J Biomed Opt. 2004;9:367-71 - PMID: 15065904 - DOI: 10.1117/1.1646413

Alt C, Framme C, Schnell S, Lee H, Brinkmann R, Lin CP

Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner. J Biomed Opt. 2006;10(6):064014 - PMID: 16409079 - DOI: 10.1117/1.2136314

Calfon MA, Vinegoni C, Ntziachristos V, Jaffer FA

Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques. J Biomed Opt. 2010;15(1):011107 - PMID: 20210433 - PMCID: PMC3188610 - DOI: 10.1117/1.3280282

Runnels JM*, Carlson AL*, Pitsillides C, Thompson B, Wu J, Spencer JA, Kohler JMJ, Azab AK, Moreau AS, Rodig SJ, Kung AL, Anderson KC, Ghobrial IM, Lin CP

Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy J Biomed Opt. 2011;16(1):011006 - PMID: 21280893 - PMCID: PMC3033873 - DOI: 10.1117/1.3520571

Hajjarian Z, Xi J, Jaffer FA, Tearney GJ, Nadkarni SK

Intravascular laser speckle imaging catheter for the mechanical evaluation of the arterial wall. J Biomed Opt. 2011;16(2):026005 - PMID: 21361689 - PMCID: PMC3056316 - DOI: 10.1117/1.3533322

Imitola J, Cote D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011;16(2):021109 - PMID: 21361672 - PMCID: PMC3061329 - DOI: 10.1117/1.3533312

Achilefu S, Contag CH, Savitsky AP, Weissleder R

Chemical and Genetic Sensors in Biomedical Research. J Biomed Opt. 2005;10(4):41201 - PMID: 23171967

Tung CH

Fluorescent peptide probes for in vivo diagnostic imaging. Biopolymers. 2004;76(5):391-403 - PMID: 15389488 - DOI: 10.1002/bip.20139

Querol Sans M*, Chen JW*, Weissleder R, Bogdanov AA

Myeloperoxidase Activity Imaging Using (67)Ga Labeled Substrate. Mol Imaging Biol. 2005;7(6):403-10 - PMID: 16292477 - DOI: 10.1007/s11307-005-0020-5

Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R

In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging. Mol Imaging Biol. 2006;8(4):201-7 - PMID: 16791746 - DOI: 10.1007/s11307-006-0043-6

Guimaraes AR, Ross R, Figuereido JL, Waterman P, Weissleder R

MRI with Magnetic Nanoparticles Monitors Downstream Anti-Angiogenic Effects of mTOR Inhibition. Mol Imaging Biol. 2011;13(2):314-20 - PMID: 20559742 - DOI: 10.1007/s11307-010-0357-2

Thurber GM, Weissleder R

Quantitating Antibody Uptake In Vivo: Conditional Dependence on Antigen Expression Levels. Mol Imaging Biol. 2011;13(4):623-32 - PMID: 20809210 - PMCID: PMC3000888 - DOI: 10.1007/s11307-010-0397-7

Mazitschek R, Baumhof P, Giannis A

Peptidomimetics and angiogenesis. Mini Rev Med Chem. 2002;2(5):491-506 - PMID: 12370049 - DOI: 10.2174/1389557023405710

Spear MA, Herrlinger U, Rainov N, Pechan P, Weissleder R, Breakefield XO

Targeting gene therapy vectors to CNS malignancies. J Neurovirol. 1998;4(2):133-47 - PMID: 9584951 - DOI: 10.3109/13550289809114514

Chang K, Jaffer F

Advances in fluorescence imaging of the cardiovascular system. J Nucl Cardiol. 2008;15(3):417-28 - PMID: 18513648 - DOI: 10.1016/j.nuclcard.2008.03.001

Lin JR, Wang H, Collins AB, Stone JR

Tongue necrosis and systemic vascular amyloidosis. Hum Pathol. 2011;42(5):734-737 - PMID: 21236468 - DOI: 10.1016/j.humpath.2010.08.011

Bouley R, Hasler U, Lu HA, Nunes P, Brown D

Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus. Semin Nephrol. 2008;28:266-78 - PMID: 18519087 - PMCID: PMC2494582 - DOI: 10.1016/j.semnephrol.2008.03.010

Brown D

Aquaporins and vasopressin signaling in kidney health and disease: introduction. Semin Nephrol. 2008;28:215-6 - PMID: 18519082 - DOI: 10.1016/j.semnephrol.2008.03.001

Yeung CH, Breton S, Setiawan I, Xu Y, Lang F, Cooper TG

Increased luminal pH in the epididymis of infertile c-ros knockout mice and the expression of sodium-hydrogen exchangers and vacuolar proton pump H+-ATPase. Mol Reprod Dev. 2004;68(2):159-68 - PMID: 15095336 - DOI: 10.1002/mrd.20067

Ho NH, Weissleder R, Tung CH

Development of water-soluble far-red fluorogenic dyes for enzyme sensing Tetrahedron. 2006;62:578-585

McCarthy JR, Capetta SH, Melfi PJ, Bruckner C

Use of Ag(II) as a removable ion in porphyrin chemistry: Diol cleavage products of [meso-tetraphenyl-2,3-diolchlorinato]Ag(II) Tetrahedron. 2003;59:9137-46

Boiselle PM, Patz EF, Vining DJ, Weissleder R, Shepard JA, McLoud TC

Imaging of mediastinal lymph nodes: CT, MR, and FDG PET. Radiographics. 1998;18(5):1061-9 - PMID: 9747607 - DOI: 10.1148/radiographics.18.5.9747607

Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W

Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Arch Pathol Lab Med. 2009;133(12):1949-53 - PMID: 19961250 - PMCID: PMC3694269 - DOI: 10.1043/1543-2165-133.12.1949

Bogdanov A, Wright SC, Marecos EM, Bogdanova A, Martin C, Petherick P, Weissleder R

A long-circulating co-polymer in "passive targeting" to solid tumors. J Drug Target. 1997;4(5):321-30 - PMID: 9169989 - DOI: 10.3109/10611869708995848

Salthouse CD, Weissleder R, Mahmood U

Development of a Time Domain Fluorimeter for Fluorescent Lifetime Multiplexing Analysis. IEEE T Biomed Circuits Syst. 2008;2(3):204-211 - PMID: 19830273 - PMCID: PMC2760943 - DOI: 10.1109/TBCAS.2008.2003195

Merkulova M, McKee M, Dip PV, Gruber G, Marshansky V

N-terminal domain of the V-ATPase a2-subunit displays integral membrane protein properties. Protein Sci. 2010;19(10):1850-1862 - PMID: 20669186 - PMCID: PMC2998721 - DOI: 10.1002/pro.470

Fumene Feruglio P, Vinegoni C, Gros J, Sbarbati A, Weissleder R

Block matching 3D random noise filtering for absorption optical projection tomography. Phys Med Biol. 2010;55(18):5401-5415 - PMID: 20736500 - PMCID: PMC2934766 - DOI: 10.1088/0031-9155/55/18/009

Soubret A, Ntziachristos V

Fluorescence molecular tomography in the presence of background fluorescence. Phys Med Biol. 2006;51:3983-4001 - PMID: 16885619 - DOI: 10.1088/0031-9155/51/16/007

Razansky D, Vinegoni C, Ntziachristos V

Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography. Phys Med Biol. 2009;54:2769-2777 - PMID: 19369709 - DOI: 10.1088/0031-9155/54/9/012

Papisov M, Weissleder R

Drug delivery to lymphatic tissue. Crit Rev Ther Drug Carrier Syst. 1996;13(1-2):57-84 - PMID: 8853959

Wiesmann F, Herold V, Streiff JU, Nahrendorf M, Neubauer S, Rommel E, Haase A

Novel insights into LV remodeling after murine myocardial infarction by in vivo magnetic resonance tissue velocity mapping. Int J Cardiovasc Imaging. 2004;20(4):289-91 - PMID: 15529911 - DOI: 10.1023/b:caim.0000041945.64887.f4

Thurber GM, Figueiredo JL, Weissleder R

Detection limits of intraoperative near infrared imaging for tumor resection. J Surg Oncol. 2010;102(7):758-64 - PMID: 20872807 - PMCID: PMC3758114 - DOI: 10.1002/jso.21735

Gomez NR, Kouniavsky G, Tsai HL, Somervell H, Pai SI, Tufano RP, Umbricht C, Kowalski J, Dackiw AP, Zeiger MA

Tumor size and presence of calcifications on ultrasonography are pre-operative predictors of lymph node metastases in patients with papillary thyroid cancer. J Surg Oncol. 2011;104(6):613-6 - PMID: 21744345 - DOI: 10.1002/jso.21891

Breton S, Tyszkowski R, Sabolic I, Brown D

Postnatal development of H+ ATPase (proton-pump)-rich cells in rat epididymis. Histochem Cell Biol. 1999;111(2):97-105 - PMID: 10090570 - DOI: 10.1007/s004180050339

Marshansky V

The V-ATPase a2-subunit as a putative endosomal pH-sensor. Biochem Soc T. 2007;35:1092-9 - PMID: 17956287 - DOI: 10.1042/BST0351092

Kelly KA, Reynolds F, Weissleder R, Josephson L

Fluorescein isothiocyanate-hapten immunoassay for determination of peptide-cell interactions. Anal Biochem. 2004;330(2):181-5 - PMID: 15203322 - DOI: 10.1016/j.ab.2004.02.035

Law B, Hsiao JK, Bugge TH, Weissleder R, Tung CH.

Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples Anal Biochem. 2005;338(1):151-158 - PMID: 15707946 - DOI: 10.1016/j.ab.2004.11.039

Laha M, Panizzi P, Nahrendorf M, Bock PE

Engineering streptokinase for generation of active site-labeled plasminogen analogs. Anal Biochem. 2011;415(2):105-15 - PMID: 21570944 - PMCID: PMC3114107 - DOI: 10.1016/j.ab.2011.04.025

Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R

Enhancing navigation in biomedical databases by community voting and database-driven text classification. BMC Bioinformatics. 2009;10(1):317 - PMID: 19799796 - PMCID: PMC2768718 - DOI: 10.1186/1471-2105-10-317

Shtatland T, Guettler D, Kossodo M, Pivovarov M, Weissleder R

PepBank - a database of peptides based on sequence text mining and public peptide data sources. BMC Bioinformatics. 2007;8(1):280 - PMID: 17678535 - PMCID: PMC1976427 - DOI: 10.1186/1471-2105-8-280

Rabkin-Aikawa E, Mayer J, Schoen F

Heart valve regeneration. Adv Biochem Eng Biot. 2005;94:141-79 - PMID: 15915872 - DOI: 10.1007/b100003

Schima W, Saini S, Petersein J, Weissleder R, Harisinghani M, Mayo-Smith W, Hahn PF

MR imaging of the liver with Gd-BOPTA: quantitative analysis of T1-weighted images at two different doses J Magn Reson Imaging. 1999;10:80-3 - PMID: 10398981 - DOI: 10.1002/(sici)1522-2586(199907)10:1<80::aid-jmri11>3.0.co;2-s

Hofmann, B, Bogdanov A Jr, Marecos E, Ebert W, Semmler W, Weissleder R

Mechanism of gadophrin-2 accumulation in tumor necrosis J Magn Reson Imaging. 1999;9:336-41 - PMID: 10077034 - DOI: 10.1002/(sici)1522-2586(199902)9:2<336::aid-jmri28>3.0.co;2-3

Enochs WS, Harsh G, Hochberg F, Weissleder R

Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent J Magn Reson Imaging. 1999;9:228-32 - PMID: 10077018 - DOI: 10.1002/(sici)1522-2586(199902)9:2<228::aid-jmri12>3.0.co;2-k

Korosoglou G, Tang L, Kedziorek D, Cosby K, Gilson WD, Vonken EJ, Schar M, Sosnovik D, Kraitchman DL, Weiss RG, Weissleder R, Stuber M

Positive contrast MR-lymphography using inversion recovery with ON-resonant water suppression (IRON). J Magn Reson Imaging. 2008;27(5):1175-1180 - PMID: 18425827 - PMCID: PMC2740932 - DOI: 10.1002/jmri.21337

Nahrendorf M, Wiesmann F, Hiller K, Hu K, Waller C, Ruff J, Lanz T, Neubauer S, Haase A, Ertl G, Bauer W

Serial cine-magnetic resonance imaging of left ventricular remodeling after myocardial infarction in rats. J Magn Reson Imaging. 2001;14(5):547-55 - PMID: 11747006 - DOI: 10.1002/jmri.1218

Hamilton AM, Rogers KA, Belisle AJ, Ronald JA, Rutt BK, Weissleder R, Boughner DR

Early identification of aortic valve sclerosis using iron oxide enhanced MRI. J Magn Reson Imaging. 2010;31(1):110-6 - PMID: 20027578 - PMCID: PMC5638659 - DOI: 10.1002/jmri.22008

Reimer P, Bader A, Weissleder R

Preclinical assessment of hepatocyte-targeted MR contrast agents in stable human liver cell cultures. J Magn Reson Imaging. 1998;8(3):687-9 - PMID: 9626887 - DOI: 10.1002/jmri.1880080326

Moore A, Weissleder R, Bogdanov A

Uptake of dextran-coated monocrystalline iron oxides in tumor cells and macrophages. J Magn Reson Imaging. 1998;7(6):1140-5 - PMID: 9400860 - DOI: 10.1002/jmri.1880070629

Weissleder R, Cheng HC, Bogdanova A, Bogdanov A

Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging. 1997;7(1):258-63 - PMID: 9039625 - DOI: 10.1002/jmri.1880070140

Stiskal M, Schwickert HC, Demsar F, Roberts TP, Szolar D, Weissleder R, Brasch RC

Contrast enhancement in experimental radiation-induced liver injury: comparison of hepatocellular and reticuloendothelial particulate contrast agents. J Magn Reson Imaging. 1997;6(2):286-90 - PMID: 9132091 - DOI: 10.1002/jmri.1880060205

Reimer P, Saini S, Kwong KK, Cohen MS, Weissleder R, Brady TJ

Dynamic gadolinium-enhanced echo-planar MR imaging of the liver: effect of pulse sequence and dose on enhancement. J Magn Reson Imaging. 1994;4(3):331-5 - PMID: 8061430 - DOI: 10.1002/jmri.1880040318

Enochs WS, Weissleder R

MR imaging of the peripheral nervous system. J Magn Reson Imaging. 1994;4(3):251-7 - PMID: 7520307 - DOI: 10.1002/jmri.1880040306

Weissleder R, Wang YM, Papisov M, Bogdanov A, Schaffer B, Brady TJ, Wittenberg J

Polymeric contrast agents for MR imaging of adrenal glands. J Magn Reson Imaging. 1993;3(1):93-7 - PMID: 8428107 - DOI: 10.1002/jmri.1880030116

Reimer P, Kwong KK, Weisskoff R, Cohen MS, Brady TJ, Weissleder R

Dynamic signal intensity changes in liver with superparamagnetic MR contrast agents. J Magn Reson Imaging. 1992;2(2):177-81 - PMID: 1562768 - DOI: 10.1002/jmri.1880020210

Weissleder R, Papisov M

Pharmaceutical iron oxides for MR imaging J Magn Reson Imaging. 1992;4:1-6

Sosnovik DE, Dai G, Nahrendorf M, Rosen BR, Seethamraju R

Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm. J Magn Reson Imaging. 2007;26(2):279-87 - PMID: 17654729 - DOI: 10.1002/jmri.20966

Streif JU, Hiller KH, Waller C, Nahrendorf M, Wiesmann F, Bauer WR, Rommel E, Haase A

In vivo assessment of absolute perfusion in the murine skeletal muscle with spin labeling MRI. Magnetic resonance imaging. J Magn Reson Imaging. 2003;17(1):147-52 - PMID: 12500285 - DOI: 10.1002/jmri.10229

Gee MS, Harisinghani MG

MRI in patients with inflammatory bowel disease. J Magn Reson Imaging. 2011;33(3):527-534 - PMID: 21512607 - PMCID: PMC3078716 - DOI: 10.1002/jmri.22504

Osborn EA, Jaffer FA

Advances in molecular imaging of atherosclerotic vascular disease. Curr Opin Cardiol. 2008;23:620-8 - PMID: 18830079 - PMCID: PMC3984946 - DOI: 10.1097/HCO.0b013e328310fc7e

Vinegoni C, Karlsson M, Petersson M, Sunnerud H

Statistics of polarization-dependent loss in a recirculating loop. J Lightwave Technol. 2004;22:968-76

Wegmuller M, Oberson P, Guinnard O, Huttner B, Guinnard L, Vinegoni C, Gisin N

Distributed gain measurements in Er-doped fibers with high resolution and accuracy using an Optical Frequency Domain Reflectometer. J Lightwave Technol. 2000;18:2127-32

Low A, O'Donnell C, Kathiresan S, Everett B, Chae C, Shaw S, Ellinor P, MacRae C

Aging syndrome genes and premature coronary artery disease. BMC Med Genet. 2005;6:38 - PMID: 16262891 - PMCID: PMC1289285 - DOI: 10.1186/1471-2350-6-38

Neuwelt EA, Weissleder R, Nilaver G, Kroll RA, Roman-Goldstein S, Szumowski J, Pagel MA, Jones RS, Remsen LG, McCormick CI

Delivery of virus-sized iron oxide particles to rodent CNS neurons. Neurosurgery. 1994;34(4):777-84 - PMID: 8008188 - DOI: 10.1227/00006123-199404000-00048

Shum WW, Ruan YC, Da Silva N, Breton S

Establishment of Cell-Cell Crosstalk in the Epididymis: Control of Luminal Acidification. J Androl. 2011;32(6):576-86 - PMID: 21441423 - PMCID: PMC3753098 - DOI: 10.2164/jandrol.111.012971

Da Silva N, Shum WW, Breton S

Regulation of vacuolar proton pumping ATPase-dependent luminal acidification in the epididymis. Asian J Androl. 2007;9(4):476-82 - PMID: 17589784 - DOI: 10.1111/j.1745-7262.2007.00299.x

Zhu B, Jaffer F, Nztiachristos V, Weissleder R

Development of a near infrared fluorescence catheter: operating characteristics and feasibility for atherosclerotic plaque detection J Phys D Appl Phys. 2005;38:2701-2707

Bogdanov A, Petherick P, Marecos E, Weissleder R

In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation. Nucl Med Biol. 1997;24(8):739-42 - PMID: 9428599 - DOI: 10.1016/s0969-8051(97)00117-0

Boland GW, Guimaraes AS, Mueller PR

The evolving radiology landscape: the importance of effective leadership. Eur J Radiol. 2009;19(10):2321-5 - PMID: 19471944 - DOI: 10.1007/s00330-009-1427-1

Weissleder R, Reimer P

Iron oxide based magnetopharmaceuticals for MR imaging Eur J Radiol. 1993;3:198-212

Ntziachristos V, Bremer C, Weissleder R

Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging Eur J Radiol. 2002;13:195-208 - PMID: 12541130 - DOI: 10.1007/s00330-002-1524-x

Bremer C, Ntziachristos V, Weissleder R

Optical-based molecular imaging: contrast agents and potential medical applications Eur J Radiol. 2002;13:231-43 - PMID: 12598985 - DOI: 10.1007/s00330-002-1610-0

Wunderbaldinger P, Bogdanov A, Weissleder R

New approaches for imaging in gene therapy Eur J Radiol. 2000;34:156-65 - PMID: 10927158 - DOI: 10.1016/s0720-048x(00)00196-0

Saksena MA, Saokar A, Harisinghani MG

Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging. Eur J Radiol. 2006;58(3):367-74 - PMID: 16472955 - DOI: 10.1016/j.ejrad.2005.12.041

Boland GW, Guimaraes AS, Mueller PR

Radiology report turnaround: expectations and solutions. Eur J Radiol. 2008;18(7):1326-8 - PMID: 18327594 - DOI: 10.1007/s00330-008-0905-1

Boland GW, Guimaraes AS, Mueller PR

The radiologist's conundrum: benefits and costs of increasing CT capacity and utilization. Eur J Radiol. 2008;19(1):9-11; discussion 12 - PMID: 18766347 - DOI: 10.1007/s00330-008-1159-7

Rajendran R*, Ronald JA*, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F

Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections. Microsc Micoranal. 2009;15:338-44 - PMID: 19575834 - PMCID: PMC2802450 - DOI: 10.1017/S1431927609090813

Berteloot A, Malo C, Breton S, Brunette M

Fast sampling, rapid filtration apparatus: principal characteristics and validation from studies of D-glucose transport in human jejunal brush-border membrane vesicles. J Membr Biol. 1991;122(2):111-25 - PMID: 1895337 - DOI: 10.1007/BF01872635

Laprade R, Lapointe JY, Breton S, Duplain M, Cardinal J

Intracellular potassium activity in mammalian proximal tubule: effect of perturbations in transepithelial sodium transport. J Membr Biol. 1991;121(3):249-59 - PMID: 1865489 - DOI: 10.1007/BF01951558

Macri P, Breton S, Marsolais M, Lapointe J, Laprade R

Hypertonicity decreases basolateral K+ and Cl- conductances in rabbit proximal convoluted tubule. J Membr Biol. 1997;155(3):229-37 - PMID: 9050446 - DOI: 10.1007/s002329900175

Brinkmann R, Koop N, Ozdemir M, Alt C, Sch

Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam. Laser Surg Med. 2003;32:252-64 - PMID: 12696092 - DOI: 10.1002/lsm.10150

Lin C, Weaver Y, Birngruber R, Fujimoto J, Puliafito CP

Intraocular microsurgery with a picosecond Nd:YAG laser. Laser Surg Med. 1995;15:44-53 - PMID: 7997047 - DOI: 10.1002/lsm.1900150107

Brinkmann R, H

Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen. Laser Surg Med. 2000;27(5):451-64 - PMID: 11126439 - DOI: 10.1002/1096-9101(2000)27:5<451::AID-LSM1006>3.0.CO;2-1

Islam T, Harisinghani MG

Prostate cancer imaging: what the next decade holds. Expert Rev Med Devices. 2010;7(5):577-9 - PMID: 20822379 - DOI: 10.1586/erd.10.43

Harisinghani MG, Saksena M, Ross RW, Tabatabaei S, Dahl D, McDougal S, Weissleder R

A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation. Urology. 2005;66(5):1066-71 - PMID: 16286125 - DOI: 10.1016/j.urology.2005.05.049

Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG

Pilot Study Evaluating Use of Lymphotrophic Nanoparticle-Enhanced Magnetic Resonance Imaging for Assessing Lymph Nodes in Renal Cell Cancer. Urology. 2008;71(4):708-12 - PMID: 18295316 - DOI: 10.1016/j.urology.2007.11.096

Pittet M, Speiser D, Valmori D, Rimoldi D, Lienard D, Lejeune F, Cerottini J, Romero P

Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients. Int Immunopharmacol. 2001;1:1235-47 - PMID: 11460305 - DOI: 10.1016/s1567-5769(01)00048-0

Simonova M, Weissleder R, Sergeyev N, Vilissova N, Bogdanov A Jr

Targeting of green fluorescent protein expression to the cell surface Biochem Bioph Res Co. 1999;262:638-42 - PMID: 10471377 - DOI: 10.1006/bbrc.1999.1251

Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH

A novel in vivo regulatory role of P-glycoprotein in alloimmunity. Biochem Bioph Res Co. 2010;394(3):646-52 - PMID: 20230790 - PMCID: PMC3756468 - DOI: 10.1016/j.bbrc.2010.03.040

Choi HK, Yessayan D, Choi HJ, Schellenberger E, Bogdanov A, Josephson L, Weissleder R, Ntziachristos V.

Quantitative analysis of chemotherapeutic effects in tumors using in vivo staining and correlative histology Cell Oncol. 2005;27(3):183-90 - PMID: 16037639 - PMCID: PMC4615174 - DOI: 10.1155/2005/791936

Schoepf U, Marecos EM, Melder RJ, Jain RK, Weissleder R

Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. Biotechniques. 1998;24(4):642-6, 648-51 - PMID: 9564539 - DOI: 10.2144/98244rr01

Hilderbrand SA, Weissleder R

One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes. Tetrahedron Lett. 2007;48(25):4383-4385 - PMID: 19834587 - PMCID: PMC2761723 - DOI: 10.1016/j.tetlet.2007.04.088

Pham W, Weissleder R, Tung CH

A practical approach for the preparation of monofunctional azulenyl squaraine dye. Tetrahedron Lett. 2003;44(20):3975-3978 - PMID: 20740053 - PMCID: PMC2926986 - DOI: 10.1016/S0040-4039(03)00819-0

Pham W, Weissleder R, Tung CH

Intermolecular [8+2] cycloaddition reactions of 2H-3-methoxycarbonylcyclohepta[b]furan-2-one with vinyl ethers: an approach to bicyclo[5.3.0]azulene derivatives. Tetrahedron Lett. 2002;43(1):19-20 - PMID: 20740048 - PMCID: PMC2926969 - DOI: 10.1016/S0040-4039(01)02061-5

Shao H, Yoon TJ, Liong M, Weissleder R, Lee H

Magnetic nanoparticles for biomedical NMR-based diagnostics Beilstein J Nanotechnol. 2010;1:142154 - PMID: 21977404 - PMCID: PMC3045933 - DOI: 10.3762/bjnano.1.17

Stone JR, Basso C, Baandrup UT, Bruneval P, Butany J, Gallagher PJ, Halushka MK, Miller DV, Padera RF, Radio SJ, Sheppard MN, Suvarna K, Tan CD, Thiene G, van der Wal AC, Veinot JP

Recommendations for processing cardiovascular surgical pathology specimens: a consensus statement from the Standards and Definitions Committee of the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology. Cardiovasc Pathol. 2011;21(1):2-16 - PMID: 21353600 - DOI: 10.1016/j.carpath.2011.01.001

Leone O, Veinot JP, Angelini A, Baandrup UT, Basso C, Berry G, Bruneval P, Burke M, Butany J, Calabrese F, d'Amati G, Edwards WD, Fallon JT, Fishbein MC, Gallagher PJ, Halushka MK, McManus B, Pucci A, Rodriguez ER, Saffitz JE, Sheppard MN, Steenbergen C, Stone JR, Tan C, Thiene G, van der Wal AC, Winters GL

2011 Consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. Cardiovasc Pathol. 2011;21(4):245-74 - PMID: 22137237 - DOI: 10.1016/j.carpath.2011.10.001

Panchenko MP, Silva N, Stone JR

Up-regulation of a hydrogen peroxide-responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasia. Cardiovasc Pathol. 2008;18(3):167-72 - PMID: 18508286 - PMCID: PMC2723736 - DOI: 10.1016/j.carpath.2008.03.008

Rabkin E, Schoen F

Cardiovascular tissue engineering. Cardiovasc Pathol. 2002;11:305-17 - PMID: 12459430 - DOI: 10.1016/s1054-8807(02)00130-8

Mendelson K, Aikawa E, Mettler B, Sales V, Martin D, Mayer J, Schoen F

Healing and remodeling of bioengineered pulmonary artery patches implanted in sheep. Cardiovasc Pathol. 2007;16:277-82 - PMID: 17868878 - DOI: 10.1016/j.carpath.2007.03.008

Collins AB, Smith RN, Stone JR

Classification of amyloid deposits in diagnostic cardiac specimens by immunofluorescence. Cardiovasc Pathol. 2008;18(4):205-16 - PMID: 18619857 - DOI: 10.1016/j.carpath.2008.05.004

Wei CL, Valvano JW, Feldman MD, Nahrendorf M, Peshock R, Pearce JA

Volume catheter parallel conductance varies between end-systole and end-diastole. IEEE T Biomed Eng. 2007;54(8):1480-9 - PMID: 17694869 - DOI: 10.1109/TBME.2007.890732

Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L

A stabilized demethoxyviridin derivative inhibits PI3 kinase. Bioorg Med Chem Lett. 2009;19(15):4223-7 - PMID: 19523825 - PMCID: PMC2877487 - DOI: 10.1016/j.bmcl.2009.05.105

Martyn DC, Cortese JF, Tyndall E, Dick J, Mazitschek R, Munoz B, Clardy J

Antiplasmodial activity of piperazine sulfonamides. Bioorg Med Chem Lett. 2009;20(1):218-21 - PMID: 19914069 - DOI: 10.1016/j.bmcl.2009.10.130

Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J

Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines. Bioorg Med Chem Lett. 2009;20(1):228-31 - PMID: 19914064 - DOI: 10.1016/j.bmcl.2009.10.133

Kim Y, Choi Y, Weissleder R, Tung CH

Membrane permeable esterase-activated fluorescent imaging probe. Bioorg Med Chem Lett. 2007;17(18):5054-7 - PMID: 17664067 - PMCID: PMC1995663 - DOI: 10.1016/j.bmcl.2007.07.026

Mazitschek R, Patel V, Wirth D, Clardy J

Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. Bioorg Med Chem Lett. 2008;18(9):2809-12 - PMID: 18430569 - PMCID: PMC2408937 - DOI: 10.1016/j.bmcl.2008.04.007

Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Hsieh YT, Kim YM, Lomenick B, Okemoto K, Landaw EM, Wang D, Mazitschek R, Bradner JE, Sakamoto KM

Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells. Leuk Lymphoma. 2011;52(8):1544-55 - PMID: 21699378 - PMCID: PMC4113006 - DOI: 10.3109/10428194.2011.570821

Haase A, Rigosi E, Frasnelli E, Trona F, Tessarolo F, Vinegoni C, Anfora G, Vallortigara G, Antolini R

A multimodal approach for tracing lateralisation along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies. Eur Biophys J. 2011;40(11):1247-1258 - PMID: 21956452 - PMCID: PMC3366498 - DOI: 10.1007/s00249-011-0748-6

Bolondi G, Garuti C, Corradini E, Zoller H, Vogel W, Finkenstedt A, Babitt JL, Lin HY, Pietrangelo A

Altered hepatic BMP signaling pathway in human HFE hemochromatosis. Blood Cells Mol Dis. 2010;45(4):308-12 - PMID: 20863724 - PMCID: PMC3295241 - DOI: 10.1016/j.bcmd.2010.08.010

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Intraoperative Near-Infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury. World J Surg. 2010;34 (2):336-343 - PMID: 20033407 - PMCID: PMC2809822 - DOI: 10.1007/s00268-009-0332-8

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Dodd CH, Hsu HC, Chu WJ, Yang P, Zhang HG, Mountz JD Jr, Zinn K, Forder J, Josephson L, Weissleder R, Mountz JM, Mountz JD

Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles J Immunol Methods. 2001;256:89-105 - PMID: 11516758 - DOI: 10.1016/s0022-1759(01)00433-1

Kuzmin A, Purans J, Cazzanelli E, Vinegoni C, Mariotto G

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Simonova M, Shtanko O, Sergeyev N, Weissleder R, Bogdanov A Jr

Engineering of technetium-99m-binding artificial receptors for imaging gene expression J Gene Med. 2003;5:1056-66 - PMID: 14661181 - DOI: 10.1002/jgm.448

Baron JM, Higgins JM, Dzik WH

A Revised Timeline for the Origin of Plasmodium falciparum as a Human Pathogen. J Mol Evol. 2011;73(5-6):297-304 - PMID: 22183792 - DOI: 10.1007/s00239-011-9476-x

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New clinical imaging modalities in prostate cancer. Hematol Oncol Clin N. 2006;20(4):811-30 - PMID: 16861116 - DOI: 10.1016/j.hoc.2006.03.009

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Evolving Role of Magnetic Resonance Imaging in Renal Cancer Imaging. J Endourol. 2010;24(5):707-11 - PMID: 20433369 - DOI: 10.1089/end.2009.0507

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Focal therapy in prostate cancer-report from a consensus panel. J Endourol. 2010;24(5):775-80 - PMID: 20477543 - DOI: 10.1089/end.2009.0596

Petersein J, Saini S, Weissleder R

Liver. II: Iron oxide-based reticuloendothelial contrast agents for MR imaging. Clinical review. Magn Reson Imaging. 1996;4(1):53-60 - PMID: 8673716

Gupta H, Weissleder R

Targeted contrast agents in MR imaging. Magn Reson Imaging. 1996;4(1):171-84 - PMID: 8673713

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An organotypical in vitro model of the liver parenchyma for uptake studies of diagnostic MR receptor agents. Magn Reson Imaging. 1996;13(7):991-1002 - PMID: 8583878 - DOI: 10.1016/0730-725x(95)00053-j

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MION-ASF: biokinetics of an MR receptor agent. Magn Reson Imaging. 1993;11(3):411-7 - PMID: 7685055 - DOI: 10.1016/0730-725x(93)90074-n

Chen MC, Tsang YM, Stark DD, Weissleder R, Saini S, Brandhorst J, White DL, Engelstad BL, Ferrucci JT

Hepatic metastases: rat models for imaging research. Magn Reson Imaging. 1989;7(1):1-8 - PMID: 2918813 - DOI: 10.1016/0730-725x(89)90318-4

Weissleder R, Stark DD, Elizondo G, Hahn PF, Compton C, Saini S, Wittenberg J, Ferrucci JT

MRI of hepatic lymphoma. Magn Reson Imaging. 1989;6(6):675-81 - PMID: 3062298 - DOI: 10.1016/0730-725x(88)90092-6

Weissleder R, Stark DD, Compton CC, Simeone JF, Ferrucci JT

Cholecystitis: diagnosis by MR imaging. Magn Reson Imaging. 1988;6(3):345-8 - PMID: 3398743 - DOI: 10.1016/0730-725x(88)90412-2

Cazzanelli E, Vinegoni C, Mariotto G, Kuzmin A, Purans J

Raman and XRD spectroscopic investigations of polymorphism in tungsten trioxide powders Solid State Ionics. 1999;123:67-74

Cazzanelli E, Vinegoni C, Mariotto G, Kuzmin A, Purans J

Comparative Raman study of the monoclinic-to-tetragonal phase transition in tungsten trioxide WO3 at high temperature and upon hydrogen insertion J Solid State Chem. 1999;143:24-32

Petersson M, Vinegoni C, Sunnerud H, Karlsson M

Statistics of PMD in recirculating loops. IEEE Photonic Tech L. 2003;15:1543-5

Vinegoni C, Chen H, Leblanc M, Schinn G, Wegmulller M, Gisin N

Distributed measurements of chromatic dispersion and nonlinear coefficient in low PMD dispersion shifted fibers IEEE Photonic Tech L. 2003;15:739-40

Wegmuller M, Demma S, Vinegoni C, Gisin N

Emulator of first- and second-order polarization mode dispersion. IEEE Photonic Tech L. 2002;14:630-2

Vinegoni C, Wegmuller M, Gisin N

Measurements of the nonlinear coefficient of standard SMF,DSF, and DSC fibers using a self-aligned interferometer and a Faraday mirror IEEE Photonic Tech L. 2001;13:1337-9

Wegmuller M, Legre M, Oberson P, Guinnard O, Guinnard L, Vinegoni C, Gisin N

Analysis of the polarization evolution in a ribbon cable using high resolution OFDR IEEE Photonic Tech L. 2000;13:145-7

Ueno T, Ikeda T, Ikeda K, Taniuchi H, Suda S, Yeung MY, Matsuno N

HMGB-1 as a Useful Prognostic Biomarker in Sepsis-Induced Organ Failure in Patients Undergoing PMX-DHP. J Surg Res. 2009;171(1):183-90 - PMID: 20338589 - DOI: 10.1016/j.jss.2009.11.708

Xia Z, Huang X, Zhou X, Sun Y, Ntziachristos V, Wong S.

Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation IEEE T Inf Technol B. 0;12:569-578

Ueno T, Omura T, Takahashi T, Matsumoto H, Takahashi Y, Kakita A, Yamashina S

Liver transplantation using liver grafts preserved under high pressure. Artif Organs. 2005;29(10):849-55 - PMID: 16185349 - DOI: 10.1111/j.1525-1594.2005.00139.x

Bruckner C, McCarthy JR, Daniell HW,

A spectroscopic and computational study of the singlet and triplet excited states of synthetic beta-functionalized chlorins Chem Phys. 2003;294:285-303

Ross R, Harisinghani M

Prostate cancer imaging-what the urologic oncologist needs to know. Radiol Clin North Am. 2006;44(5):711-22 - PMID: 17030222 - DOI: 10.1016/j.rcl.2006.07.002

Kim YR, Savellano MD, Weissleder R, Bogdanov A Jr

Steady-state and dynamic contrast MR imaging of human prostate cancer xenograft tumors: a comparative study Technol Cancer Res T. 2002;1:489-95 - PMID: 12625776 - DOI: 10.1177/153303460200100609

Vinegoni C, Cazzanelli M, Trivelli A, Lunney GJ, Mariotto G, Levy J

Morphological and optical characterization of GaN prepared by pulsed laser ablation Surf Coat Tech. 2000;124:272-7

Bogdanov AA Jr, Simonova M, Weissleder R

Engineering membrane proteins for nuclear medicine: applications for gene therapy and cell tracking Q J Nucl Med Mol IM. 2000;44:224-35 - PMID: 11105587

Saokar A, Braschi M, Harisinghani M

Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging. Abdom Imaging. 2006;31(6):660-7 - PMID: 16680506 - DOI: 10.1007/s00261-006-9006-2

Bouley R, Hawthorn G, Russo L, Lin HY, Ausiello D, Brown D

Aquaporin 2 (AQP2) and vasopressin receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in "endocytosis-resistant" membrane domains after vasopressin treatment. Abdom Imaging. 2005;:ePub - PMID: 16104839

Roedl JB, Blake MA, Holalkere NS, Mueller PR, Colen RR, Harisinghani MG

Lymph node staging in esophageal adenocarcinoma with PET-CT based on a visual analysis and based on metabolic parameters. Abdom Imaging. 2008;34(5):610-7 - PMID: 18830663 - DOI: 10.1007/s00261-008-9447-x

Lee DK, Nahrendorf M, Schellingerhout D, Kim DE

Will molecular optical imaging have clinically important roles in stroke management, and how? J Clin Neurol. 2010;6(1):10-8 - PMID: 20386638 - PMCID: PMC2851295 - DOI: 10.3988/jcn.2010.6.1.10

Cazzanelli M, Vinegoni C, Lunney JG, O'Donnel KP, Middleton PG, Trager-Cowan C, Pavesi L

Luminescence properties of GaN thin films prepared by pulsed laser deposition Mat Sci Eng B-Solid. 1999;59:137-140

Harisinghani MG, Jhaveri KS, Weissleder R, Schima W, Saini S, Hahn PF, Mueller PR

MRI contrast agents for evaluating focal hepatic lesions Clin Radiol. 2001;56:714-25 - PMID: 11585393 - DOI: 10.1053/crad.2001.0764

Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M

Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy. Clin Imaging. 2009;33(4):301-5 - PMID: 19559353 - DOI: 10.1016/j.clinimag.2009.01.013

Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG

Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. Clin Imaging. 2010;34(1):20-28 - PMID: 20122515 - DOI: 10.1016/j.clinimag.2009.03.012

Saokar A, Islam T, Jantsch M, Saksena MA, Hahn PF, Harisinghani MG

Detection of lymph nodes in pelvic malignancies with computed tomography and magnetic resonance imaging. Clin Imaging. 2010;34(5):361-6 - PMID: 20813300 - DOI: 10.1016/j.clinimag.2009.07.004

Saokar A, Gee MS, Islam T, Mueller PR, Harisinghani MG

Appearance of primary lymphoid malignancies on lymphotropic nanoparticle-enhanced magnetic resonance imaging using ferumoxtran-10. Clin Imaging. 2010;34(6):448-52 - PMID: 21092874 - DOI: 10.1016/j.clinimag.2009.09.008

Johnson J, Swirski F, Gajewska B, Wiley R, Fattouh R, Pacitto S, Wong J, Stampfli M, Jordana M

Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes. Am J Physiol-Lung C. 2007;293:L730-9 - PMID: 17586699 - DOI: 10.1152/ajplung.00056.2007

Vinegoni C, Wegmuller M, Huttner B, Gisin N

Measurement of nonlinear polarization rotation in high birefringence optical fibers at telecom wavelength. 2000;2;314-184 J Opt A-Pure Appl Opt . 2000;2:314-184

Grimm J, Wunder A.

Current state of molecular imaging research Rofo-Fortschr Rontg. 2005;177(3):326-37 - PMID: 15719293 - DOI: 10.1055/s-2005-857946

Gao M, Lewis G, Turner GM, Soubret A, Ntziachristos V.

Effects of background fluorescence in fluorescence molecular tomography Appl Optics. 2005;44(26):5468-74 - PMID: 16161661 - DOI: 10.1364/ao.44.005468

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Precise, controlled laser delivery with evanescent optical waves. Appl Optics. 1999;38(25):5511-7 - PMID: 18324060 - DOI: 10.1364/ao.38.005511

Cazzanelli E, Mariotto G, Vinegoni C, Kuzmin A, Purans J

Color centers and polymorphism in pure and WO3 and mixed ReO3-WO3 powders. Ionics 2000;5;335-44 Ionics. 2000;5:335-44

Graves EE, Culver JP, Ripoll J, Weissleder R, Ntziachristos V

Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography J Opt Soc Am A . 2004;21(2):231-41 - PMID: 14763766 - DOI: 10.1364/josaa.21.000231

Coutinho AC, Krishnaraj A, Pires CE, Bittencourt LK, Guimaraes AR

Pelvic applications of diffusion magnetic resonance images. Magn Reson Imaging Clin N Am. 2011;19(1):133-57 - PMID: 21129639 - DOI: 10.1016/j.mric.2010.10.003

Tan W, Vinegoni C, Norman J, Desai T, Boppart S

Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Techniq. 2007;70(4):361-71 - PMID: 17262787 - DOI: 10.1002/jemt.20420

Harisinghani MG, Saini S, Weissleder R, Rubin D, deLange E, Harms S, Weinreb J, Small W, Sukerkar A, Brown JJ, Zelch J, Lucas M, Morris M, Hahn PF

Splenic imaging with ultrasmall superparamagnetic iron oxide ferumoxtran-10 (AMI-7227): preliminary observations J Comput Assist Tomogr. 2001;25:770-6 - PMID: 11584239 - DOI: 10.1097/00004728-200109000-00017

Li CS, Harisinghani MG, Lin WC, Braschi M, Hahn PF, Mueller PR

Enhancement Characteristics of Ultrasmall Superparamagnetic Iron Oxide Particle Within the Prostate Gland in Patients With Primary Prostate Cancer. J Comput Assist Tomogr. 2008;32:523-528 - PMID: 18664836 - DOI: 10.1097/RCT.0b013e318136e194

Prakash P, Kalra MK, Stone JR, Shepard JA, Digumarthy SR

Imaging findings of pericardial metastasis on chest computed tomography. J Comput Assist Tomogr. 2010;34(4):554-8 - PMID: 20657224 - DOI: 10.1097/RCT.0b013e3181d77d7e

Shenoy-Bhangle A, Nimkin K, Gee MS

Pediatric imaging: Current and emerging techniques. J Postgrad Med. 2010;56(2):98-102 - PMID: 20622388 - DOI: 10.4103/0022-3859.65273

Sanghvi D, Harisinghani MG

Modalities in modern radiology: A synopsis. J Postgrad Med. 2010;56(2):85-7 - PMID: 20622386 - DOI: 10.4103/0022-3859.65282

Ueno T, Sugino M, Nemoto H, Shoji H, Kakita A, Watanabe M

Effect over time of endotoxin adsorption therapy in sepsis. Ther Apher Dial. 2005;9(2):128-36 - PMID: 15828924 - DOI: 10.1111/j.1774-9987.2005.00230.x

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In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036

Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE

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Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE

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Vinegoni C, Wegmuller M, Huttner B, Gisin N

All optical switching in a highly birefringent and a standard telecom fiber using a Faraday mirror stabilization scheme. Opt Commun. 2000;182:314-18

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Sonographic findings of an adrenal leiomyosarcoma. J Ultrasound Med. 2010;29(9):1369-73 - PMID: 20733196 - DOI: 10.7863/jum.2010.29.9.1369

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Sonographic diagnosis of subclavian and internal jugular vein thrombosis. J Ultrasound Med. 1987;6(10):577-87 - PMID: 3316690 - DOI: 10.7863/jum.1987.6.10.577

Gee MS, Harisinghani MG, Tabatabaei S

Molecular imaging in urologic surgery. Urol Clin N Am. 2009;36(2):125-32 - PMID: 19406314 - DOI: 10.1016/j.ucl.2009.02.007

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Labels and probes for live cell imaging: overview and selection guide. Methods Mol Biol. 2009;591:17-45 - PMID: 19957122 - DOI: 10.1007/978-1-60761-404-3_2

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In Vivo Imaging of the Dynamics of Different Variants of EGFR in Glioblastomas. Methods Mol Biol. 2010;680:153-164 - PMID: 21153380 - DOI: 10.1007/978-1-60761-901-7_11

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Intravital Fluorescence Microscopic Molecular Imaging of Atherosclerosis. Methods Mol Biol. 2010;680:131-140 - PMID: 21153378 - PMCID: PMC3051165 - DOI: 10.1007/978-1-60761-901-7_9

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Imaging Fate of Stem Cells at a Cellular Resolution in the Brains of Mice. Methods Mol Biol. 2010;680:91-101 - PMID: 21153375 - DOI: 10.1007/978-1-60761-901-7_6

Haun JB, Yoon TJ, Lee H, Weissleder R

Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance. Methods Mol Biol. 2011;726:33-49 - PMID: 21424441 - DOI: 10.1007/978-1-61779-052-2_3

Weissleder R, Stark DD

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Malka R, Lerner B

Classification of fluorescence in-situ hybridization images using belief networks Pattern Recogn Lett. 2004;25(16):1777-85

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Molecular imaging of cell-based therapies. Neuroimag Clin N Am.. 2004;14(2):331-42 - PMID: 15182822 - DOI: 10.1016/j.nic.2004.03.009

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