Pai SI, Wasserman I, Ji YD, Gilman M, Hung YP, Faquin WC, Mino-Kenudson M, Muniappan A

Pulmonary manifestations of chronic HPV infection in patients with recurrent respiratory papillomatosis Lancet Respir Med. 2022;10(10):997-1008 - PMID: 35863360 - PMCID: PMC10634185 - DOI: 10.1016/S2213-2600(22)00008-X

Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med. 2014;20(11):1301-9 - PMID: 25344738 - DOI: 10.1038/nm.3708

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA

Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors. Nat Med. 2019;25(8):1264-1269 - PMID: 31263286 - PMCID: PMC6919319 - DOI: 10.1038/s41591-019-0493-4

Cejas P, Drier Y, Dreijerink KMA, Brosens LAA, Deshpande V, Epstein CB, Conemans EB, Morsink FHM, Graham MK, Valk GD, Vriens MR, Castillo CF, Ferrone CR, Adar T, Bowden M, Whitton HJ, Da Silva A, Font-Tello A, Long HW, Gaskell E, Shoresh N, Heaphy CM, Sicinska E, Kulke MH, Chung DC, Bernstein BE, Shivdasani RA

Publisher Correction: Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors. Nat Med. 2019;25(10):1627 - PMID: 31501535 - DOI: 10.1038/s41591-019-0573-5

Chandrasekhar A, Padrós-Valls R, Pallarès-López R, Palanques-Tost E, Houstis N, Sundt TM, Lee HS, Sodini CG, Aguirre AD

Tissue perfusion pressure enables continuous hemodynamic evaluation and risk prediction in the intensive care unit. Nat Med. 2023;29(8):1998-2006 - PMID: 37550417 - DOI: 10.1038/s41591-023-02474-6

Harisinghani MG, Barentsz J, Hahn PF, Deserno WM, Tabatabaei S, van de Kaa CH, de la Rosette J, Weissleder R

Noninvasive detection of clinically occult lymph-node metastases in prostate cancer N Engl J Med. 2003;348:2491-9 - PMID: 12815134 - DOI: 10.1056/NEJMoa022749

Merkel PA, McCarty D, Sharma A, Stone JR

Case records of the Massachusetts General Hospital. Case 31-2008. A 39-year-old man with chest pain, arthralgias, and a mediastinal mass. N Engl J Med. 2008;359:1603-14 - PMID: 18843125 - DOI: 10.1056/NEJMcpc0805310

Brass SD, Durand ML, Stone JH, Chen JW, Stone JR

Case records of the Massachusetts General Hospital. Case 36-2008. A 59-year-old man with chronic daily headache. N Engl J Med. 2008;359(21):2267-78 - PMID: 19020329 - DOI: 10.1056/NEJMcpc0805313

Kaufman DS, McDougal WS, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 30-2009. A 77-year-old man with recurrent transitional-cell carcinoma of the ureter. N Engl J Med. 2009;361(13):1292-9 - PMID: 19776411 - DOI: 10.1056/NEJMcpc0900642

Stone JH, Papaliodis GN, Dunbar MR, Stone JR

Case 4-2010 -- a 53-year-old man with arthralgias, oral ulcers, vision loss, and vocal-cord paralysis. N Engl J Med. 2010;362(6):537-46 - PMID: 20147720 - DOI: 10.1056/NEJMcpc0910090

Ng AK, Abramson JS, Digumarthy SR, Reingold JS, Stone JR

Case 24-2010. N Engl J Med. 2010;363(7):664-675 - PMID: 20818858 - DOI: 10.1056/NEJMcpc1004087

Sabatine MS, Jaffer FA, Staats PN, Stone JR

Case records of the Massachusetts General Hospital. Case 28-2010. A 32-year-old woman, 3 weeks post partum, with substernal chest pain. N Engl J Med. 2010;363(12):1164-73 - PMID: 20843252 - DOI: 10.1056/NEJMcpc1000966

Karchmer AW, MacGillivray TE, Healey TT, Stone JR

Case records of the Massachusetts General Hospital. Case 1-2011. A 35-year-old man with fever, bacteremia, and a mass in the left atrium. N Engl J Med. 2011;364(2):158-66 - PMID: 21226582 - DOI: 10.1056/NEJMcpc1004362

Kaufman DS, Zietman AL, Dahl DM, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 5-2011. A 65-year-old man with hematuria after treatment for prostate cancer. N Engl J Med. 2011;364(7):667-75 - PMID: 21323545 - DOI: 10.1056/NEJMcpc1005310

Kaufman DS, Zietman AL, McDougal WS, Dahl DM, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 9-2012. A 67-year-old man with a persistently elevated PSA level. N Engl J Med. 2012;366(12):1143-50 - PMID: 22435374 - DOI: 10.1056/NEJMcpc1104320

Bazari H, Guimaraes AR, Kushner YB

Case records of the Massachusetts General Hospital. Case 20-2012. A 77-year-old man with leg edema, hematuria, and acute renal failure. N Engl J Med. 2012;366(26):2503-15 - PMID: 22738101 - DOI: 10.1056/NEJMcpc1111577

Hunt DP, Becker AE, Guimaraes AR, Stemmer-Rachamimov A, Misdraji J

Case records of the Massachusetts General Hospital. Case 21-2012. A 27-year-old man with fatigue, weakness, weight loss, and decreased libido. N Engl J Med. 2012;367(2):157-69 - PMID: 22784119 - DOI: 10.1056/NEJMcpc1110053

Zella GC, Gee MS, Badizadegan K

Case records of the Massachusetts General Hospital. Case 25-2012. A 15-year-old boy with abdominal pain, hematochezia, and anemia. N Engl J Med. 2012;367(7):659-67 - PMID: 22894579 - DOI: 10.1056/NEJMcpc1111578

Stone JH, Patel VI, Oliveira GR, Stone JR

Case 38-2012. N Engl J Med. 2012;367(24):2335-46 - PMID: 23234517 - DOI: 10.1056/NEJMcpc1209330

Steele DJ, Kasmar AG, Guimaraes AR, Dekker JP

Case records of the Massachusetts General Hospital. Case 3-2013. A 72-year-old woman with abdominal pain and distention after peritoneal dialysis. N Engl J Med. 2013;368(4):375-85 - PMID: 23343067 - DOI: 10.1056/NEJMcpc1208142

Simmons LH, Guimaraes AR, Zukerberg LR

Case 6-2013. N Engl J Med. 2013;368(8):757-65 - PMID: 23425169 - DOI: 10.1056/NEJMcpc1208149

Awad MM, Katayama R, McTigue M, Liu W, Deng YL, Brooun A, Friboulet L, Huang D, Falk MD, Timofeevski S, Wilner KD, Lockerman EL, Khan TM, Mahmood S, Gainor JF, Digumarthy SR, Stone JR, Mino-Kenudson M, Christensen JG, Iafrate AJ, Engelman JA, Shaw AT

Acquired Resistance to Crizotinib from a Mutation in CD74-ROS1. N Engl J Med. 2013;368(25):2395-401 - PMID: 23724914 - PMCID: PMC3878821 - DOI: 10.1056/NEJMoa1215530

Olumi AF, Kaufman DS, Zietman A, Harisinghani MG, Wu CL

Case records of the Massachusetts General Hospital. Case 25-2013. A 71-year-old man with hematuria and a mass in the bladder. N Engl J Med. 2013;369(7):660-7 - PMID: 23944304 - DOI: 10.1056/NEJMcpc1209278

Baggett MV, Turbett SE, Schwartzenberg SS, Stone JR

Case records of the Massachusetts General Hospital: Case 5-2014: 2014: A 59-year-old man with fever, confusion, thrombocytopenia, rash, and renal failure. N Engl J Med. 2014;370(7):651-60 - PMID: 24521112 - DOI: 10.1056/NEJMcpc1310004

Jaiswal S, Fontanillas P, Flannick J, Manning A, Grauman PV, Mar BG, Lindsley RC, Mermel CH, Burtt N, Chavez A, Higgins JM, Moltchanov V, Kuo FC, Kluk MJ, Henderson B, Kinnunen L, Koistinen HA, Ladenvall C, Getz G, Correa A, Banahan BF, Gabriel S, Kathiresan S, Stringham HM, McCarthy MI, Boehnke M, Tuomilehto J, Haiman C, Groop L, Atzmon G, Wilson JG, Neuberg D, Altshuler D, Ebert BL

Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes. N Engl J Med. 2014;371(26):2488-2498 - PMID: 25426837 - PMCID: PMC4306669 - DOI: 10.1056/NEJMoa1408617

Hogan C, Little BP, Carlson JCT, Freudenreich O, Ivkovic A, Baron JM

Case 5-2019: A 48-Year-Old Woman with Delusional Thinking and Paresthesia of the Right Hand. N Engl J Med. 2019;380(7):665-674 - PMID: 30763197 - DOI: 10.1056/NEJMcpc1807495

Carlson JCT, Hogan C, Ivkovic A

Case 5-2019: A Woman with Delusional Thinking and Paresthesia of the Right Hand. Reply. N Engl J Med. 2019;380(21):2082 - PMID: 31116941 - DOI: 10.1056/NEJMc1903635

Finn KM, Sutphin PD, Carlson JCT, Raskin KA, Van Cott EM

Case 17-2021: An 82-Year-Old Woman with Pain, Swelling, and Ecchymosis of the Left Arm. N Engl J Med. 2021;384(23):2242-2250 - PMID: 34107184 - DOI: 10.1056/NEJMcpc2100281

Carlson JCT, Sertic MM, Chen MY

Case 6-2024: A 21-Year-Old Man with Fatigue and Night Sweats. N Engl J Med. 2024;390(8):747-756 - PMID: 38381678 - DOI: 10.1056/NEJMcpc2309498

Weissleder R, Lee H

Automated molecular-image cytometry and analysis in modern oncology Nature Review Materials. 2020;:ePub - DOI: 10.1038/s41578-020-0180-6

Weissleder R

Scaling down imaging: molecular mapping of cancer in mice Nat Rev Cancer. 2002;2:1-8 - PMID: 11902581 - DOI: 10.1038/nrc701

Engblom C, Pfirschke C, Pittet MJ

The role of myeloid cells in cancer therapies. Nat Rev Cancer. 2016;16(7):447-62 - PMID: 27339708 - DOI: 10.1038/nrc.2016.54

Miller MA, Weissleder R

Imaging of anticancer drug action in single cells Nat Rev Cancer. 2017;17(7):399–414 - PMID: 28642603 - PMCID: PMC7552440 - DOI: 10.1038/nrc.2017.41

Naxerova K

Evolutionary paths towards metastasis. Nat Rev Cancer. 2025;25(7):545-560 - PMID: 40263543 - DOI: 10.1038/s41568-025-00814-x

Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T

Restoration of p53 function leads to tumour regression in vivo. Nature. 2007;445:661-5 - PMID: 17251932 - DOI: 10.1038/nature05541

Weissleder R, Pittet MJ

Imaging in the era of molecular oncology Nature. 2008;452:580-589 - PMID: 18385732 - PMCID: PMC2708079 - DOI: 10.1038/nature06917

Celso CL, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, Cote D, Rowe DW, Lin CP, Scadden DT.

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276 - DOI: 10.1038/nature07434

Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH

HDAC2 negatively regulates memory formation and synaptic plasticity. Nature. 2009;459(7243):55-60 - PMID: 19424149 - PMCID: PMC3498958 - DOI: 10.1038/nature07925

Mikkelsen T, Ku M, Jaffe D, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim T, Koche R, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, Xie X, Meissner A, Wernig M, Jaenisch R, Nusbaum C, Lander E, Bernstein B

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature. 2007;448(7153):553-60 - PMID: 17603471 - PMCID: PMC2921165 - DOI: 10.1038/nature06008

Sipkins DA, Wei X, Wu JW, Runnels JM, Cote D, Means TK, Luster AD, Scadden DT, Lin CP

In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment. Nature. 2005;435:969-73 - PMID: 15959517 - PMCID: PMC2570168 - DOI: 10.1038/nature03703

Adams GB, Alley IR, Chung UI, Chabner KT, Jeanson NT, Lo Celso C, Marsters ES, Chen M, Weinstein LS, Lin CP, Kronenberg HM, Scadden DT

Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow. Nature. 2009;459(7243):103-7 - PMID: 19322176 - PMCID: PMC2761017 - DOI: 10.1038/nature07859

Lo Celso C, Fleming HE, Wu JW, Zhao CX, Miake-Lye S, Fujisaki J, C

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche. Nature. 2009;457(7225):92-6 - PMID: 19052546 - PMCID: PMC2820276 - DOI: 10.1038/nature07434

Sachidanandam R, Weissman D, Schmidt SC, Kakol JM, Stein LD, Marth G, Sherry S, Mullikin JC, Mortimore BJ, Willey DL, Hunt SE, Cole CG, Coggill PC, Rice CM, Ning Z, Rogers J, Bentley DR, Kwok PY, Mardis ER, Yeh RT, Schultz B, Cook L, Davenport R, Dante M, Fulton L, Hillier L, Waterston RH, McPherson JD, Gilman B, Schaffner S, Van Etten WJ, Reich D, Higgins J, Daly MJ, Blumenstiel B, Baldwin J, Stange-Thomann N, Zody MC, Linton L, Lander ES, Altshuler D,

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms. Nature. 2001;409(6822):928-33 - PMID: 11237013 - DOI: 10.1038/35057149

Sabeti PC, Reich DE, Higgins JM, Levine HZ, Richter DJ, Schaffner SF, Gabriel SB, Platko JV, Patterson NJ, McDonald GJ, Ackerman HC, Campbell SJ, Altshuler D, Cooper R, Kwiatkowski D, Ward R, Lander ES

Detecting recent positive selection in the human genome from haplotype structure. Nature. 2002;419(6909):832-7 - PMID: 12397357 - DOI: 10.1038/nature01140

Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ

Epigenetic memory in induced pluripotent stem cells. Nature. 2010;467(7313):285-90 - PMID: 20644535 - PMCID: PMC3150836 - DOI: 10.1038/nature09342

Chapman MA, Lawrence MS, Keats JJ, Cibulskis K, Sougnez C, Schinzel AC, Harview CL, Brunet JP, Ahmann GJ, Adli M, Anderson KC, Ardlie KG, Auclair D, Baker A, Bergsagel PL, Bernstein BE, Drier Y, Fonseca R, Gabriel SB, Hofmeister CC, Jagannath S, Jakubowiak AJ, Krishnan A, Levy J, Liefeld T, Lonial S, Mahan S, Mfuko B, Monti S, Perkins LM, Onofrio R, Pugh TJ, Rajkumar SV, Ramos AH, Siegel DS, Sivachenko A, Stewart AK, Trudel S, Vij R, Voet D, Winckler W, Zimmerman T, Carpten J, Trent J, Hahn WC, Garraway LA, Meyerson M, Lander ES, Getz G, Golub TR

Initial genome sequencing and analysis of multiple myeloma. Nature. 2011;471(7339):467-72 - PMID: 21430775 - PMCID: PMC3560292 - DOI: 10.1038/nature09837

Ernst J, Kheradpour P, Mikkelsen TS, Shoresh N, Ward LD, Epstein CB, Zhang X, Wang L, Issner R, Coyne M, Ku M, Durham T, Kellis M, Bernstein BE

Mapping and analysis of chromatin state dynamics in nine human cell types. Nature. 2011;473(7345):43-9 - PMID: 21441907 - PMCID: PMC3088773 - DOI: 10.1038/nature09906

Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Celso CL, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, Lin CP

In vivo imaging of T(reg) cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 2011;474(7350):216-9 - PMID: 21654805 - PMCID: PMC3725645 - DOI: 10.1038/nature10160

Dutta P*, Courties G*, Wei Y, Leuschner F, Gorbatov R, Robbins CS, Iwamoto Y, Thompson B, Carlson AL, Heidt T, Majmudar MD, Lasitschka F, Etzrodt M, Waterman P, Waring MT, Chicoine AT, van der Laan AN, Niessen HWM, Piek JJ, Rubin BB, Butany J, Stone JR, Katus HA, Murphy SA, Morrow DA, Sabatine MS, Vinegoni C, Moskowitz MA, Pittet MJ, Libby P, Lin CP, Swirski FK, Weissleder R, Nahrendorf M

Myocardial infarction accelerates atherosclerosis Nature. 2012;487(7407):325-9 - PMID: 22763456 - PMCID: PMC3401326 - DOI: 10.1038/nature11260

Koppikar P, Bhagwat N, Kilpivaara O, Manshouri T, Adli M, Hricik T, Liu F, Saunders LM, Mullally A, Abdel-Wahab O, Leung L, Weinstein A, Marubayashi S, Goel A, Gönen M, Estrov Z, Ebert BL, Chiosis G, Nimer SD, Bernstein BE, Verstovsek S, Levine RL

Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy. Nature. 2012;489(7414):155-9 - PMID: 22820254 - PMCID: PMC3991463 - DOI: 10.1038/nature11303

ENCODE Project Consortium, Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, Snyder M

An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489(7414):57-74 - PMID: 22955616 - PMCID: PMC3439153 - DOI: 10.1038/nature11247

Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, Kohlbacher O, De Jager PL, Rosen ED, Bennett DA, Bernstein BE, Gnirke A, Meissner A

Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013;500(7463):477-81 - PMID: 23925113 - PMCID: PMC3821869 - DOI: 10.1038/nature12433

Tata PR, Mou H, Pardo-Saganta A, Zhao R, Prabhu M, Law BM, Vinarsky V, Cho JL, Breton S, Sahay A, Medoff BD, Rajagopal J

Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature. 2013;503(7475):218-23 - PMID: 24196716 - PMCID: PMC4035230 - DOI: 10.1038/nature12777

Guttman M, Amit I, Garber M, French C, Lin MF, Feldser D, Huarte M, Zuk O, Carey BW, Cassady JP, Cabili MN, Jaenisch R, Mikkelsen TS, Jacks T, Hacohen N, Bernstein BE, Kellis M, Regev A, Rinn JL, Lander ES

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature. 2009;458(7235):223-7 - PMID: 19182780 - PMCID: PMC2754849 - DOI: 10.1038/nature07672

Meissner A, Mikkelsen TS, Gu H, Wernig M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES

Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature. 2008;454(7205):766-70 - PMID: 18600261 - PMCID: PMC2896277 - DOI: 10.1038/nature07107

Mikkelsen TS, Hanna J, Zhang X, Ku M, Wernig M, Schorderet P, Bernstein BE, Jaenisch R, Lander ES, Meissner A

Dissecting direct reprogramming through integrative genomic analysis. Nature. 2008;454(7200):49-55 - PMID: 18509334 - PMCID: PMC2754827 - DOI: 10.1038/nature07056

Spencer JA, Ferraro F, Roussakis E, Klein A, Wu J, Runnels JM, Zaher W, Mortensen LJ, Alt C, Turcotte R, Yusuf R, Côté D, Vinogradov SA, Scadden DT, Lin CP

Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature. 2014;508(7495):269-73 - PMID: 24590072 - PMCID: PMC3984353 - DOI: 10.1038/nature13034

Ksander BR, Kolovou PE, Wilson BJ, Saab KR, Guo Q, Ma J, McGuire SP, Gregory MS, Vincent WJ, Perez VL, Cruz-Guilloty F, Kao WW, Call MK, Tucker BA, Zhan Q, Murphy GF, Lathrop KL, Alt C, Mortensen LJ, Lin CP, Zieske JD, Frank MH, Frank NY

ABCB5 is a limbal stem cell gene required for corneal development and repair. Nature. 2014;511(7509):353-7 - PMID: 25030174 - PMCID: PMC4246512 - DOI: 10.1038/nature13426

Farh KK, Marson A, Zhu J, Kleinewietfeld M, Housley WJ, Beik S, Shoresh N, Whitton H, Ryan RJ, Shishkin AA, Hatan M, Carrasco-Alfonso MJ, Mayer D, Luckey CJ, Patsopoulos NA, De Jager PL, Kuchroo VK, Epstein CB, Daly MJ, Hafler DA, Bernstein BE

Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature. 2014;518(7539):337-43 - PMID: 25363779 - PMCID: PMC4336207 - DOI: 10.1038/nature13835

Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cacchiarelli D, Tsankov AM, Epstein C, Rinn JL, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A

Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature. 2014;518(7539):355-9 - PMID: 25533951 - PMCID: PMC4336237 - DOI: 10.1038/nature13990

Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J, Ziller MJ, Amin V, Whitaker JW, Schultz MD, Ward LD, Sarkar A, Quon G, Sandstrom RS, Eaton ML, Wu YC, Pfenning AR, Wang X, Claussnitzer M, Liu Y, Coarfa C, Harris RA, Shoresh N, Epstein CB, Gjoneska E, Leung D, Xie W, Hawkins RD, Lister R, Hong C, Gascard P, Mungall AJ, Moore R, Chuah E, Tam A, Canfield TK, Hansen RS, Kaul R, Sabo PJ, Bansal MS, Carles A, Dixon JR, Farh KH, Feizi S, Karlic R, Kim AR, Kulkarni A, Li D, Lowdon R, Elliott G, Mercer TR, Neph SJ, Onuchic V, Polak P, Rajagopal N, Ray P, Sallari RC, Siebenthall KT, Sinnott-Armstrong NA, Stevens M, Thurman RE, Wu J, Zhang B, Zhou X, Beaudet AE, Boyer LA, De Jager PL, Farnham PJ, Fisher SJ, Haussler D, Jones SJ, Li W, Marra MA, McManus MT, Sunyaev S, Thomson JA, Tlsty TD, Tsai LH, Wang W, Waterland RA, Zhang MQ, Chadwick LH, Bernstein BE, Costello JF, Ecker JR, Hirst M, Meissner A, Milosavljevic A, Ren B, Stamatoyannopoulos JA, Wang T, Kellis M

Integrative analysis of 111 reference human epigenomes. Nature. 2015;518(7539):317-30 - PMID: 25693563 - PMCID: PMC4530010 - DOI: 10.1038/nature14248

Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE

Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature. 2015;529(7584):110-4 - PMID: 26700815 - PMCID: PMC4831574 - DOI: 10.1038/nature16490

Itkin T, Gur-Cohen S, Spencer JA, Schajnovitz A, Ramasamy SK, Kusumbe AP, Ledergor G, Jung Y, Milo I, Poulos MG, Kalinkovich A, Ludin A, Golan K, Khatib E, Kumari A, Kollet O, Shakhar G, Butler JM, Rafii S, Adams RH, Scadden DT, Lin CP, Lapidot T

Distinct bone marrow blood vessels differentially regulate haematopoiesis. Nature. 2016;532(7599):323-328 - PMID: 27074509 - PMCID: PMC6450701 - DOI: 10.1038/nature17624

Tirosh I, Venteicher AS, Hebert C, Escalante LE, Patel AP, Yizhak K, Fisher JM, Rodman C, Mount C, Filbin MG, Neftel C, Desai N, Nyman J, Izar B, Luo CC, Francis JM, Patel AA, Onozato ML, Riggi N, Livak KJ, Gennert D, Satija R, Nahed BV, Curry WT, Martuza RL, Mylvaganam R, Iafrate AJ, Frosch MP, Golub TR, Rivera MN, Getz G, Rozenblatt-Rosen O, Cahill DP, Monje M, Bernstein BE, Louis DN, Regev A, Suvà ML

Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma. Nature. 2016;539(7628):309-313 - PMID: 27806376 - PMCID: PMC5465819 - DOI: 10.1038/nature20123

Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature. 2017;547(7663):355-359 - PMID: 28678782 - PMCID: PMC5896562 - DOI: 10.1038/nature23000

He S*, Kahles F*, Rattik S*, Nairz M, McAlpine CS, Anzai A, Selgrade D, Fenn AM, Chan CT, Mindur JE, Valet C, Poller WC, Halle L, Rotllan N, Iwamoto Y, Wojtkiewicz GR, Weissleder R, Libby P, Fernández-Hernando C, Drucker DJ, Nahrendorf M, Swirski FK

Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease Nature. 2019;566(7742):115-119 - PMID: 30700910 - PMCID: PMC6367023 - DOI: 10.1038/s41586-018-0849-9

McAlpine CS, Kiss MG, Rattik S, He S, Vassalli A, Valet C, Anzai A, Chan CT, Mindur JE, Kahles F, Poller WC, Frodermann V, Fenn AM, Gregory AF, Halle L, Iwamoto Y, Hoyer FF, Binder CJ, Libby P, Tafti M, Scammell TE, Nahrendorf M, Swirski FK

Sleep modulates haematopoiesis and protects against atherosclerosis Nature. 2019;566(7744):383-387 - PMID: 30760925 - PMCID: PMC6442744 - DOI: 10.1038/s41586-019-0948-2

Hovestadt V, Smith KS, Bihannic L, Filbin MG, Shaw ML, Baumgartner A, DeWitt JC, Groves A, Mayr L, Weisman HR, Richman AR, Shore ME, Goumnerova L, Rosencrance C, Carter RA, Phoenix TN, Hadley JL, Tong Y, Houston J, Ashmun RA, DeCuypere M, Sharma T, Flasch D, Silkov A, Ligon KL, Pomeroy SL, Rivera MN, Rozenblatt-Rosen O, Rusert JM, Wechsler-Reya RJ, Li XN, Peyrl A, Gojo J, Kirchhofer D, Lötsch D, Czech T, Dorfer C, Haberler C, Geyeregger R, Halfmann A, Gawad C, Easton J, Pfister SM, Regev A, Gajjar A, Orr BA, Slavc I, Robinson GW, Bernstein BE, Suvà ML, Northcott PA

Resolving medulloblastoma cellular architecture by single-cell genomics. Nature. 2019;572(7767):74-79 - PMID: 31341285 - PMCID: PMC6754173 - DOI: 10.1038/s41586-019-1434-6

Flavahan WA, Drier Y, Johnstone SE, Hemming ML, Tarjan DR, Hegazi E, Shareef SJ, Javed NM, Raut CP, Eschle BK, Gokhale PC, Hornick JL, Sicinska ET, Demetri GD, Bernstein BE

Altered chromosomal topology drives oncogenic programs in SDH-deficient GIST. Nature. 2019;:ePub - PMID: 31618758 - DOI: 10.1038/s41586-019-1668-3

Vagnozzi RJ, Maillet M, Sargent MA, Khalil H, Johansen AK, Schwanekamp JA, York AJ, Huang V, Nahrendorf M, Sadayappan S, Molkentin JD

An acute immune response underlies the benefit of cardiac stem-cell therapy. Nature. 2019;577(7790):405-409 - PMID: 31775156 - PMCID: PMC6962570 - DOI: 10.1038/s41586-019-1802-2

Swirski FK

Platelets have a dangerous hold over immune cells in cardiovascular disease. Nature. 2020;577(7790):323-324 - PMID: 31937950 - DOI: 10.1038/d41586-019-03732-9

Christodoulou C, Spencer JA, Yeh SA, Turcotte R, Kokkaliaris KD, Panero R, Ramos A, Guo G, Seyedhassantehrani N, Esipova TV, Vinogradov SA, Rudzinskas S, Zhang Y, Perkins AS, Orkin SH, Calogero RA, Schroeder T, Lin CP, Camargo FD

Live-animal imaging of native haematopoietic stem and progenitor cells. Nature. 2020;578(7794):278-283 - PMID: 32025033 - PMCID: PMC7021587 - DOI: 10.1038/s41586-020-1971-z

ENCODE Project Consortium, Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z

Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature. 2020;583(7818):699-710 - PMID: 32728249 - PMCID: PMC7410828 - DOI: 10.1038/s41586-020-2493-4

ENCODE Project Consortium, Snyder MP, Gingeras TR, Moore JE, Weng Z, Gerstein MB, Ren B, Hardison RC, Stamatoyannopoulos JA, Graveley BR, Feingold EA, Pazin MJ, Pagan M, Gilchrist DA, Hitz BC, Cherry JM, Bernstein BE, Mendenhall EM, Zerbino DR, Frankish A, Flicek P, Myers RM

Perspectives on ENCODE. Nature. 2020;583(7818):693-698 - PMID: 32728248 - PMCID: PMC7410827 - DOI: 10.1038/s41586-020-2449-8

Choi S, Zhang B, Ma S, Gonzalez-Celeiro M, Stein D, Jin X, Kim ST, Kang YL, Besnard A, Rezza A, Grisanti L, Buenrostro JD, Rendl M, Nahrendorf M, Sahay A, Hsu YC

Corticosterone inhibits GAS6 to govern hair follicle stem-cell quiescence Nature. 2021;592(7854):428-432 - PMID: 33790465 - PMCID: PMC8923613 - DOI: 10.1038/s41586-021-03417-2

Griffin GK, Wu J, Iracheta-Vellve A, Patti JC, Hsu J, Davis T, Dele-Oni D, Du PP, Halawi AG, Ishizuka JJ, Kim SY, Klaeger S, Knudsen NH, Miller BC, Nguyen TH, Olander KE, Papanastasiou M, Rachimi S, Robitschek EJ, Schneider EM, Yeary MD, Zimmer MD, Jaffe JD, Carr SA, Doench JG, Haining WN, Yates KB, Manguso RT, Bernstein BE

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity. Nature. 2021;595(7866):309-314 - PMID: 33953401 - PMCID: PMC9166167 - DOI: 10.1038/s41586-021-03520-4

McAlpine CS, Park J, Griciuc A, Kim E, Choi SH, Iwamoto Y, Kiss MG, Christie KA, Vinegoni C, Poller WC, Mindur JE, Chan CT, He S, Janssen H, Wong LP, Downey J, Singh S, Anzai A, Kahles F, Jorfi M, Feruglio PF, Sadreyev RI, Weissleder R, Kleinstiver BP, Nahrendorf M, Tanzi RE, Swirski FK

Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease Nature. 2021;595(7869):701-706 - PMID: 34262178 - PMCID: PMC8934148 - DOI: 10.1038/s41586-021-03734-6

Naxerova K

Mutation fingerprints encode cellular histories. Nature. 2021;597(7876):334-336 - PMID: 34433973 - DOI: 10.1038/d41586-021-02269-0

Gorelick AN, Naxerova K

Mutational clocks tick differently across species. Nature. 2022;604(7906):435-436 - PMID: 35418556 - DOI: 10.1038/d41586-022-00976-w

Poller WC, Downey J, Mooslechner AA, Khan N, Li L, Chan CT, McAlpine CS, Xu C, Kahles F, He S, Janssen H, Mindur JE, Singh S, Kiss MG, Alonso-Herranz L, Iwamoto Y, Kohler RH, Wong LP, Chetal K, Russo SJ, Sadreyev RI, Weissleder R, Nahrendorf M, Frenette PS, Divangahi M, Swirski FK

Brain motor and fear circuits regulate leukocytes during acute stress. Nature. 2022;607(7919):578-584 - PMID: 35636458 - PMCID: PMC9798885 - DOI: 10.1038/s41586-022-04890-z

Chaffin M, Papangeli I, Simonson B, Akkad AD, Hill MC, Arduini A, Fleming SJ, Melanson M, Hayat S, Kost-Alimova M, Atwa O, Ye J, Bedi KC, Nahrendorf M, Kaushik VK, Stegmann CM, Margulies KB, Tucker NR, Ellinor PT

Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy. Nature. 2022;608(7921):174-180 - PMID: 35732739 - PMCID: PMC12591363 - DOI: 10.1038/s41586-022-04817-8

Hwang WL, Deindl S, Harada BT, Zhuang X

Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA. Nature. 2014;512(7513):213-7 - PMID: 25043036 - PMCID: PMC4134374 - DOI: 10.1038/nature13380

Sun Y, Revach OY, Anderson S, Kessler EA, Wolfe CH, Jenney A, Mills CE, Robitschek EJ, Davis TGR, Kim S, Fu A, Ma X, Gwee J, Tiwari P, Du PP, Sindurakar P, Tian J, Mehta A, Schneider AM, Yizhak K, Sade-Feldman M, LaSalle T, Sharova T, Xie H, Liu S, Michaud WA, Saad-Beretta R, Yates KB, Iracheta-Vellve A, Spetz JKE, Qin X, Sarosiek KA, Zhang G, Kim JW, Su MY, Cicerchia AM, Rasmussen MQ, Klempner SJ, Juric D, Pai SI, Miller DM, Giobbie-Hurder A, Chen JH, Pelka K, Frederick DT, Stinson S, Ivanova E, Aref AR, Paweletz CP, Barbie DA, Sen DR, Fisher DE, Corcoran RB, Hacohen N, Sorger PK, Flaherty KT, Boland GM, Manguso RT, Jenkins RW

Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature. 2023;615(7950):158-167 - PMID: 36634707 - PMCID: PMC10171827 - DOI: 10.1038/s41586-023-05704-6

Oliveira G, Stromhaug K, Cieri N, Iorgulescu JB, Klaeger S, Wolff JO, Rachimi S, Chea V, Krause K, Freeman SS, Zhang W, Li S, Braun DA, Neuberg D, Carr SA, Livak KJ, Frederick DT, Fritsch EF, Wind-Rotolo M, Hacohen N, Sade-Feldman M, Yoon CH, Keskin DB, Ott PA, Rodig SJ, Boland GM, Wu CJ

Landscape of helper and regulatory antitumour CD4+ T cells in melanoma. Nature. 2022;605(7910):532-538 - PMID: 35508657 - PMCID: PMC9815755 - DOI: 10.1038/s41586-022-04682-5

Li J, Hubisz MJ, Earlie EM, Duran MA, Hong C, Varela AA, Lettera E, Deyell M, Tavora B, Havel JJ, Phyu SM, Amin AD, Budre K, Kamiya E, Cavallo JA, Garris C, Powell S, Reis-Filho JS, Wen H, Bettigole S, Khan AJ, Izar B, Parkes EE, Laughney AM, Bakhoum SF

Non-cell-autonomous cancer progression from chromosomal instability. Nature. 2023;620(7976):1080-1088 - PMID: 37612508 - PMCID: PMC10468402 - DOI: 10.1038/s41586-023-06464-z

Wu Q, Zhang J, Kumar S, Shen S, Kincaid M, Johnson CB, Zhang YS, Turcotte R, Alt C, Ito K, Homan S, Sherman BE, Shao TY, Slaughter A, Weinhaus B, Song B, Filippi MD, Grimes HL, Lin CP, Ito K, Way SS, Kofron JM, Lucas D

Resilient anatomy and local plasticity of naive and stress haematopoiesis. Nature. 2024;627(8005):839-846 - PMID: 38509363 - PMCID: PMC10972750 - DOI: 10.1038/s41586-024-07186-6

Foy BH, Petherbridge R, Roth MT, Zhang C, De Souza DC, Mow C, Patel HR, Patel CH, Ho SN, Lam E, Powe CE, Hasserjian RP, Karczewski KJ, Tozzo V, Higgins JM

Haematological setpoints are a stable and patient-specific deep phenotype. Nature. 2024;637(8045):430-438 - PMID: 39663453 - PMCID: PMC12085991 - DOI: 10.1038/s41586-024-08264-5

Xie X, Zhang O, Yeo MJR, Lee C, Tao R, Harry SA, Payne NC, Nam E, Paul L, Li Y, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB

Converging mechanism of UM171 and KBTBD4 neomorphic cancer mutations. Nature. 2025;639(8053):241-249 - PMID: 39939763 - PMCID: PMC11882451 - DOI: 10.1038/s41586-024-08533-3

Yeo MJR, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Nguyen K, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Carr SA, Udeshi ND, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N

UM171 glues asymmetric CRL3-HDAC1/2 assembly to degrade CoREST corepressors. Nature. 2025;639(8053):232-240 - PMID: 39939761 - PMCID: PMC11882444 - DOI: 10.1038/s41586-024-08532-4

Ling AL, Solomon IH, Landivar AM, Nakashima H, Woods JK, Santos A, Masud N, Fell G, Mo X, Yilmaz AS, Grant J, Zhang A, Bernstock JD, Torio E, Ito H, Liu J, Shono N, Nowicki MO, Triggs D, Halloran P, Piranlioglu R, Soni H, Stopa B, Bi WL, Peruzzi P, Chen E, Malinowski SW, Prabhu MC, Zeng Y, Carlisle A, Rodig SJ, Wen PY, Lee EQ, Nayak L, Chukwueke U, Gonzalez Castro LN, Dumont SD, Batchelor T, Kittelberger K, Tikhonova E, Miheecheva N, Tabakov D, Shin N, Gorbacheva A, Shumskiy A, Frenkel F, Aguilar-Cordova E, Aguilar LK, Krisky D, Wechuck J, Manzanera A, Matheny C, Tak PP, Barone F, Kovarsky D, Tirosh I, Suvà ML, Wucherpfennig KW, Ligon K, Reardon DA, Chiocca EA

Clinical trial links oncolytic immunoactivation to survival in glioblastoma. Nature. 2023;623(7985):157-166 - PMID: 37853118 - PMCID: PMC10620094 - DOI: 10.1038/s41586-023-06623-2

Baruch EN, Gleber-Netto FO, Nagarajan P, Rao X, Akhter S, Eichwald T, Xie T, Balood M, Adewale A, Naara S, Sathishkumar HN, Islam S, McCarthy W, Mattson BJ, Ferrarotto R, Wong MK, Davies MA, Jindal S, Basu S, Roversi K, Nikpoor AR, Ahmadi M, Ahmadi A, Harwood C, Leigh I, Gong D, Tallón de Lara P, Tao DL, Davidson TM, Ajami NJ, Futreal A, Rai K, Kochat V, Castillo M, Gunaratne P, Goepfert RP, Hernandez SD, Khushalani NI, Wang J, Watowich SS, Calin GA, Migden MR, Yuan M, Liu N, Ye Y, Hwang WL, Vermeer PD, D'Silva NJ, Bunimovich YL, Yaniv D, Burks JK, Gomez J, Dougherty PM, Tsai KY, Allison JP, Sharma P, Wargo JA, Myers JN, Talbot S, Gross ND, Amit M

Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy. Nature. 2025;646(8084):462-473 - PMID: 40836096 - PMCID: PMC12406299 - DOI: 10.1038/s41586-025-09370-8

Ventura A, Young A, Winslow M, Lintault L, Meissner A, Erkeland S, Newman J, Bronson R, Crowley D, Stone J, Jaenisch R, Sharp P, Jacks T

Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 2008;132(5):875-86 - PMID: 18329372 - PMCID: PMC2323338 - DOI: 10.1016/j.cell.2008.02.019

Shum WW, Da Silva N, McKee M, Smith PJ, Brown D, Breton S

Transepithelial Projections from Basal Cells are Luminal Sensors in Pseudostratified Epithelia Cell. 2008;135:1108-17 - PMID: 19070580 - PMCID: PMC2646085 - DOI: 10.1016/j.cell.2008.10.020

Bernstein B, Meissner A, Lander E

The mammalian epigenome. Cell. 2007;128(4):669-81 - PMID: 17320505 - DOI: 10.1016/j.cell.2007.01.033

Bernstein B, Mikkelsen T, Xie X, Kamal M, Huebert D, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber S, Lander E

A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell. 2006;125(2):315-26 - PMID: 16630819 - DOI: 10.1016/j.cell.2006.02.041

Bernstein B, Kamal M, Lindblad-Toh K, Bekiranov S, Bailey D, Huebert D, McMahon S, Karlsson E, Kulbokas E, Gingeras T, Schreiber S, Lander E

Genomic maps and comparative analysis of histone modifications in human and mouse. Cell. 2005;120(2):169-81 - PMID: 15680324 - DOI: 10.1016/j.cell.2005.01.001

Schreiber S, Bernstein B

Signaling network model of chromatin. Cell. 2002;111(6):771-8 - PMID: 12526804 - DOI: 10.1016/s0092-8674(02)01196-0

Zhong L, D'Urso A, Toiber D, Sebastian C, Henry RE, Vadysirisack DD, Guimaraes A, Marinelli B, Wikstrom JD, Nir T, Clish CB, Vaitheesvaran B, Iliopoulos O, Kurland I, Dor Y, Weissleder R, Shirihai OS, Ellisen LW, Espinosa JM, Mostoslavsky R

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1alpha. Cell. 2010;140(2):280-293 - PMID: 20141841 - PMCID: PMC2821045 - DOI: 10.1016/j.cell.2009.12.041

Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG

Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains. Cell. 2011;144(4):513-25 - PMID: 21335234 - PMCID: PMC3572774 - DOI: 10.1016/j.cell.2011.01.020

Walhout AJM, Aebersold R, Meyer T, Bork P, Kirschner MW

Systems Biology: What's the Next Challenge? Cell. 2011;144:6

Pittet MJ, Weissleder R

Intravital imaging. Cell. 2011;147(5):983-91 - PMID: 22118457 - PMCID: PMC3824153 - DOI: 10.1016/j.cell.2011.11.004

Ram O, Goren A, Amit I, Shoresh N, Yosef N, Ernst J, Kellis M, Gymrek M, Issner R, Coyne M, Durham T, Zhang X, Donaghey J, Epstein CB, Regev A, Bernstein BE

Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells. Cell. 2011;147(7):1628-39 - PMID: 22196736 - PMCID: PMC3312319 - DOI: 10.1016/j.cell.2011.09.057

Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, Depinho RA

Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism. Cell. 2012;149(3):656-70 - PMID: 22541435 - PMCID: PMC3472002 - DOI: 10.1016/j.cell.2012.01.058

Zullo JM, Demarco IA, Piqué-Regi R, Gaffney DJ, Epstein CB, Spooner CJ, Luperchio TR, Bernstein BE, Pritchard JK, Reddy KL, Singh H

DNA sequence-dependent compartmentalization and silencing of chromatin at the nuclear lamina. Cell. 2012;149(7):1474-87 - PMID: 22726435 - DOI: 10.1016/j.cell.2012.04.035

Sebastián C, Zwaans BM, Silberman DM, Gymrek M, Goren A, Zhong L, Ram O, Truelove J, Guimaraes AR, Toiber D, Cosentino C, Greenson JK, Macdonald AI, McGlynn L, Maxwell F, Edwards J, Giacosa S, Guccione E, Weissleder R, Bernstein BE, Regev A, Shiels PG, Lombard DB, Mostoslavsky R

The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism. Cell. 2012;151(6):1185-99 - PMID: 23217706 - PMCID: PMC3526953 - DOI: 10.1016/j.cell.2012.10.047

Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, Durham T, Miri M, Deshpande V, De Jager PL, Bennett DA, Houmard JA, Muoio DM, Onder TT, Camahort R, Cowan CA, Meissner A, Epstein CB, Shoresh N, Bernstein BE

Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues. Cell. 2013;152(3):642-54 - PMID: 23333102 - PMCID: PMC3563935 - DOI: 10.1016/j.cell.2012.12.033

Gifford CA, Ziller MJ, Gu H, Trapnell C, Donaghey J, Tsankov A, Shalek AK, Kelley DR, Shishkin AA, Issner R, Zhang X, Coyne M, Fostel JL, Holmes L, Meldrim J, Guttman M, Epstein C, Park H, Kohlbacher O, Rinn J, Gnirke A, Lander ES, Bernstein BE, Meissner A

Transcriptional and Epigenetic Dynamics during Specification of Human Embryonic Stem Cells. Cell. 2013;153(5):1149-1163 - PMID: 23664763 - PMCID: PMC3709577 - DOI: 10.1016/j.cell.2013.04.037

Suvà ML, Rheinbay E, Gillespie SM, Patel AP, Wakimoto H, Rabkin SD, Riggi N, Chi AS, Cahill DP, Nahed BV, Curry WT, Martuza RL, Rivera MN, Rossetti N, Kasif S, Beik S, Kadri S, Tirosh I, Wortman I, Shalek AK, Rozenblatt-Rosen O, Regev A, Louis DN, Bernstein BE

Reconstructing and Reprogramming the Tumor-Propagating Potential of Glioblastoma Stem-like Cells. Cell. 2014;157(3):580-94 - PMID: 24726434 - PMCID: PMC4004670 - DOI: 10.1016/j.cell.2014.02.030

Aceto N, Bardia A, Miyamoto DT, Donaldson MC, Wittner BS, Spencer JA, Yu M, Pely A, Engstrom A, Zhu H, Brannigan BW, Kapur R, Stott SL, Shioda T, Ramaswamy S, Ting DT, Lin CP, Toner M, Haber DA, Maheswaran S

Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell. 2014;158(5):1110-22 - PMID: 25171411 - PMCID: PMC4149753 - DOI: 10.1016/j.cell.2014.07.013

Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA

Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis. Cell. 2015;160(6):1246-60 - PMID: 25748654 - PMCID: PMC4380877 - DOI: 10.1016/j.cell.2015.02.038

Liu J, Lee J, Salazar Hernandez MA, Mazitschek R, Ozcan U

Treatment of obesity with celastrol. Cell. 2015;161(5):999-1011 - PMID: 26000480 - PMCID: PMC4768733 - DOI: 10.1016/j.cell.2015.05.011

Garris CS, Pittet MJ

ER Stress in Dendritic Cells Promotes Cancer. Cell. 2015;161(7):1492-3 - PMID: 26091029 - DOI: 10.1016/j.cell.2015.06.006

Yu VW, Yusuf RZ, Oki T, Wu J, Saez B, Wang X, Cook C, Baryawno N, Ziller MJ, Lee E, Gu H, Meissner A, Lin CP, Kharchenko PV, Scadden DT

Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells. Cell. 2016;167(5):1310-1322.e17 - PMID: 27863245 - DOI: 10.1016/j.cell.2016.10.045

Hulsmans M, Clauss S, Xiao L, Aguirre AD, King KR, Hanley A, Hucker WJ, Wülfers EM, Seemann G, Courties G, Iwamoto Y, Sun Y, Savol AJ, Sager HB, Lavine KJ, Fishbein GA, Capen DE, Da Silva N, Miquerol L, Wakimoto H, Seidman CE, Seidman JG, Sadreyev RI, Naxerova K, Mitchell RN, Brown D, Libby P, Weissleder R, Swirski FK, Kohl P, Vinegoni C, Milan DJ, Ellinor PT, Nahrendorf M

Macrophages Facilitate Electrical Conduction in the Heart Cell. 2017;169:510-522 - PMID: 28431249 - PMCID: PMC5474950 - DOI: 10.1016/j.cell.2017.03.050

Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, Omer AD, Robinson JT, Schlick T, Bernstein BE, Casellas R, Lander ES, Aiden EL

Cohesin Loss Eliminates All Loop Domains. Cell. 2017;171(2):305-320.e24 - PMID: 28985562 - PMCID: PMC5846482 - DOI: 10.1016/j.cell.2017.09.026

Puram SV, Tirosh I, Parikh AS, Patel AP, Yizhak K, Gillespie S, Rodman C, Luo CL, Mroz EA, Emerick KS, Deschler DG, Varvares MA, Mylvaganam R, Rozenblatt-Rosen O, Rocco JW, Faquin WC, Lin DT, Regev A, Bernstein BE

Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer. Cell. 2017;171(7):1611-1624.e24 - PMID: 29198524 - PMCID: PMC5878932 - DOI: 10.1016/j.cell.2017.10.044

Sack LM, Davoli T, Li MZ, Li Y, Xu Q, Naxerova K, Wooten EC, Bernardi RJ, Martin TD, Chen T, Leng Y, Liang AC, Scorsone KA, Westbrook TF, Wong KK, Elledge SJ

Profound Tissue Specificity in Proliferation Control Underlies Cancer Drivers and Aneuploidy Patterns. Cell. 2018;173(2):499-514.e23 - PMID: 29576454 - PMCID: PMC6643283 - DOI: 10.1016/j.cell.2018.02.037

McBrayer SK, Mayers JR, DiNatale GJ, Shi DD, Khanal J, Chakraborty AA, Sarosiek KA, Briggs KJ, Robbins AK, Sewastianik T, Shareef SJ, Olenchock BA, Parker SJ, Tateishi K, Spinelli JB, Islam M, Haigis MC, Looper RE, Ligon KL, Bernstein BE, Carrasco RD, Cahill DP, Asara JM, Metallo CM, Yennawar NH, Vander Heiden MG, Kaelin WG

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma. Cell. 2018;175(1):101-116.e25 - PMID: 30220459 - PMCID: PMC6219629 - DOI: 10.1016/j.cell.2018.08.038

van Galen P, Hovestadt V, Wadsworth Ii MH, Hughes TK, Griffin GK, Battaglia S, Verga JA, Stephansky J, Pastika TJ, Lombardi Story J, Pinkus GS, Pozdnyakova O, Galinsky I, Stone RM, Graubert TA, Shalek AK, Aster JC, Lane AA, Bernstein BE

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity. Cell. 2019;176(6):1265-1281.e24 - PMID: 30827681 - PMCID: PMC6515904 - DOI: 10.1016/j.cell.2019.01.031

Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, Druck N, Rodman C, Dionne D, Kaplan A, Bertalan MS, Small J, Pelton K, Becker S, Bonal D, Nguyen QD, Servis RL, Fung JM, Mylvaganam R, Mayr L, Gojo J, Haberler C, Geyeregger R, Czech T, Slavc I, Nahed BV, Curry WT, Carter BS, Wakimoto H, Brastianos PK, Batchelor TT, Stemmer-Rachamimov A, Martinez-Lage M, Frosch MP, Stamenkovic I, Riggi N, Rheinbay E, Monje M, Rozenblatt-Rosen O, Cahill DP, Patel AP, Hunter T, Verma IM, Ligon KL, Louis DN, Regev A, Bernstein BE, Tirosh I, Suvà ML

An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. 2019;178(4):835-849.e21 - PMID: 31327527 - PMCID: PMC6703186 - DOI: 10.1016/j.cell.2019.06.024

Johnstone SE, Reyes A, Qi Y, Adriaens C, Hegazi E, Pelka K, Chen JH, Zou LS, Drier Y, Hecht V, Shoresh N, Selig MK, Lareau CA, Iyer S, Nguyen SC, Joyce EF, Hacohen N, Irizarry RA, Zhang B, Aryee MJ, Bernstein BE

Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer. Cell. 2020;182(6):1474-1489.e23 - PMID: 32841603 - PMCID: PMC7575124 - DOI: 10.1016/j.cell.2020.07.030

Heyde A, Rohde D, McAlpine CS, Zhang S, Hoyer FF, Gerold JM, Cheek D, Iwamoto Y, Schloss MJ, Vandoorne K, Iborra-Egea O, Muñoz-Guijosa C, Bayes-Genis A, Reiter JG, Craig M, Swirski FK, Nahrendorf M, Nowak MA, Naxerova K

Increased stem cell proliferation in atherosclerosis accelerates clonal hematopoiesis Cell. 2021;184(5):1348-1361.e22 - PMID: 33636128 - PMCID: PMC8109274 - DOI: 10.1016/j.cell.2021.01.049

Nuñez JK, Chen J, Pommier GC, Cogan JZ, Replogle JM, Adriaens C, Ramadoss GN, Shi Q, Hung KL, Samelson AJ, Pogson AN, Kim JYS, Chung A, Leonetti MD, Chang HY, Kampmann M, Bernstein BE, Hovestadt V, Gilbert LA, Weissman JS

Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. 2021;184(9):2503-2519.e17 - PMID: 33838111 - PMCID: PMC8376083 - DOI: 10.1016/j.cell.2021.03.025

Cheek DM, Naxerova K

Mapping the long road to cancer. Cell. 2022;185(6):939-940 - PMID: 35263624 - DOI: 10.1016/j.cell.2022.02.020

Burger ML, Cruz AM, Crossland GE, Gaglia G, Ritch CC, Blatt SE, Bhutkar A, Canner D, Kienka T, Tavana SZ, Barandiaran AL, Garmilla A, Schenkel JM, Hillman M, de Los Rios Kobara I, Li A, Jaeger AM, Hwang WL, Westcott PMK, Manos MP, Holovatska MM, Hodi FS, Regev A, Santagata S, Jacks T

Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors. Cell. 2021;184(19):4996-5014.e26 - PMID: 34534464 - PMCID: PMC8522630 - DOI: 10.1016/j.cell.2021.08.020

Deindl S, Hwang WL, Hota SK, Blosser TR, Prasad P, Bartholomew B, Zhuang X

ISWI remodelers slide nucleosomes with coordinated multi-base-pair entry steps and single-base-pair exit steps. Cell. 2013;152(3):442-52 - PMID: 23374341 - PMCID: PMC3647478 - DOI: 10.1016/j.cell.2012.12.040

Gungabeesoon J, Gort-Freitas NA, Kiss M, Bolli E, Messemaker M, Siwicki M, Hicham M, Bill R, Koch P, Cianciaruso C, Duval F, Pfirschke C, Mazzola M, Peters S, Homicsko K, Garris C, Weissleder R, Klein AM, Pittet MJ

A neutrophil response linked to tumor control in immunotherapy. Cell. 2023;186(7):1448-1464.e20 - PMID: 37001504 - PMCID: PMC10132778 - DOI: 10.1016/j.cell.2023.02.032

Perez JM, Josephson L, O'Loughlin T, Hogemann D, Weissleder R

Magnetic relaxation switches capable of sensing molecular interactions Nat Biotechnol. 2002;20:816-20 - PMID: 12134166 - DOI: 10.1038/nbt720

Weissleder R

A clearer vision for in vivo imaging Nat Biotechnol. 2001;19:316-7 - PMID: 11283581 - DOI: 10.1038/86684

Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R

Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells Nat Biotechnol. 2000;18:410-4 - PMID: 10748521 - DOI: 10.1038/74464

Weissleder R, Tung CH, Mahmood U, Bogdanov A Jr

In vivo imaging of tumors with protease-activated near-infrared fluorescent probes Nat Biotechnol. 1999;17:375-8 - PMID: 10207887 - DOI: 10.1038/7933

Ntziachristos V, Ripoll J, Wang L, Weissleder R

Looking and Listening to light: the evolution of whole-body photonic imaging Nat Biotechnol. 2005;23:313-320 - PMID: 15765087 - DOI: 10.1038/nbt1074

Weissleder R, Kelly K, Sun E, Shtatland T, Josephson L.

Cell-specific targeting of nanoparticles by multivalent attachment of small molecules Nat Biotechnol. 2005;23:1418-1423 - PMID: 16244656 - DOI: 10.1038/nbt1159

Peterson R, Shaw S, Peterson T, Milan D, Zhong T, Schreiber S, MacRae C, Fishman M

Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation. Nat Biotechnol. 2004;22(5):595-9 - PMID: 15097998 - DOI: 10.1038/nbt963

Harris RA, Wang T, Coarfa C, Nagarajan RP, Hong C, Downey SL, Johnson BE, Fouse SD, Delaney A, Zhao Y, Olshen A, Ballinger T, Zhou X, Forsberg KJ, Gu J, Echipare L, O'Geen H, Lister R, Pelizzola M, Xi Y, Epstein CB, Bernstein BE, Hawkins RD, Ren B, Chung WY, Gu H, Bock C, Gnirke A, Zhang MQ, Haussler D, Ecker JR, Li W, Farnham PJ, Waterland RA, Meissner A, Marra MA, Hirst M, Milosavljevic A, Costello JF

Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications. Nat Biotechnol. 2010;28(10):1097-105 - PMID: 20852635 - PMCID: PMC2955169 - DOI: 10.1038/nbt.1682

Bernstein BE, Stamatoyannopoulos JA, Costello JF, Ren B, Milosavljevic A, Meissner A, Kellis M, Marra MA, Beaudet AL, Ecker JR, Farnham PJ, Hirst M, Lander ES, Mikkelsen TS, Thomson JA

The NIH Roadmap Epigenomics Mapping Consortium. Nat Biotechnol. 2010;28(10):1045-8 - PMID: 20944595 - PMCID: PMC3607281 - DOI: 10.1038/nbt1010-1045

Leuschner F, Dutta P, Gorbatov R, Novobrantseva TI, Donahoe JS, Courties G, Lee KM, Kim JI, Markmann JF, Marinelli B, Panizzi P, Lee WW, Iwamoto Y, Milstein S, Epstein-Barash H, Cantley W, Wong J, Cortez-Retamozo V, Newton A, Love K, Libby P, Pittet MJ, Swirski FK, Koteliansky V, Langer R, Weissleder R, Anderson DG, Nahrendorf M

Therapeutic siRNA silencing in inflammatory monocytes in mice Nat Biotechnol. 2011;29(11):1005-10 - PMID: 21983520 - PMCID: PMC3212614 - DOI: 10.1038/nbt.1989

Mendenhall EM, Williamson KE, Reyon D, Zou JY, Ram O, Joung JK, Bernstein BE

Locus-specific editing of histone modifications at endogenous enhancers. Nat Biotechnol. 2013;31(12):1133-6 - PMID: 24013198 - PMCID: PMC3858395 - DOI: 10.1038/nbt.2701

Zangi L, Lui KO, von Gise A, Ma Q, Ebina W, Ptaszek LM, Später D, Xu H, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction. Nat Biotechnol. 2013;31(10):898-907 - PMID: 24013197 - PMCID: PMC4058317 - DOI: 10.1038/nbt.2682

Maeder ML, Angstman JF, Richardson ME, Linder SJ, Cascio VM, Tsai SQ, Ho QH, Sander JD, Reyon D, Bernstein BE, Costello JF, Wilkinson MF, Joung JK

Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins. Nat Biotechnol. 2013;31(12):1137-42 - PMID: 24108092 - PMCID: PMC3858462 - DOI: 10.1038/nbt.2726

Im H*, Shao H*, Park YI, Peterson VM, Castro CM, Weissleder R*, Lee H*

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor Nat Biotechnol. 2014;32(5):490-5 - PMID: 24752081 - PMCID: PMC4356947 - DOI: 10.1038/nbt.2886

Rotem A, Ram O, Shoresh N, Sperling RA, Goren A, Weitz DA, Bernstein BE

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state. Nat Biotechnol. 2015;33(11):1165-72 - PMID: 26458175 - PMCID: PMC4636926 - DOI: 10.1038/nbt.3383

Najm FJ, Strand C, Donovan KF, Hegde M, Sanson KR, Vaimberg EW, Sullender ME, Hartenian E, Kalani Z, Fusi N, Listgarten J, Younger ST, Bernstein BE, Root DE, Doench JG

Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens. Nat Biotechnol. 2017;36(2):179-189 - PMID: 29251726 - PMCID: PMC5800952 - DOI: 10.1038/nbt.4048

Whitman JD, Hiatt J, Mowery CT, Shy BR, Yu R, Yamamoto TN, Rathore U, Goldgof GM, Whitty C, Woo JM, Gallman AE, Miller TE, Levine AG, Nguyen DN, Bapat SP, Balcerek J, Bylsma SA, Lyons AM, Li S, Wong AW, Gillis-Buck EM, Steinhart ZB, Lee Y, Apathy R, Lipke MJ, Smith JA, Zheng T, Boothby IC, Isaza E, Chan J, Acenas DD, Lee J, Macrae TA, Kyaw TS, Wu D, Ng DL, Gu W, York VA, Eskandarian HA, Callaway PC, Warrier L, Moreno ME, Levan J, Torres L, Farrington LA, Loudermilk RP, Koshal K, Zorn KC, Garcia-Beltran WF, Yang D, Astudillo MG, Bernstein BE, Gelfand JA, Ryan ET, Charles RC, Iafrate AJ, Lennerz JK, Miller S, Chiu CY, Stramer SL, Wilson MR, Manglik A, Ye CJ, Krogan NJ, Anderson MS, Cyster JG, Ernst JD, Wu AHB, Lynch KL, Bern C, Hsu PD, Marson A

Evaluation of SARS-CoV-2 serology assays reveals a range of test performance. Nat Biotechnol. 2020;38(10):1174-1183 - PMID: 32855547 - PMCID: PMC7740072 - DOI: 10.1038/s41587-020-0659-0

Shareef SJ, Bevill SM, Raman AT, Aryee MJ, van Galen P, Hovestadt V, Bernstein BE

Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells. Nat Biotechnol. 2021;39(9):1086-1094 - PMID: 33958785 - PMCID: PMC8434949 - DOI: 10.1038/s41587-021-00910-x

Millar DG, Ramjiawan RR, Kawaguchi K, Gupta N, Chen J, Zhang S, Nojiri T, Ho WW, Aoki S, Jung K, Chen I, Shi F, Heather JM, Shigeta K, Morton LT, Sepulveda S, Wan L, Joseph R, Minogue E, Khatri A, Bardia A, Ellisen LW, Corcoran RB, Hata AN, Pai SI, Jain RK, Fukumura D, Duda DG, Cobbold M

Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy. Nat Biotechnol. 2020;38(4):420-425 - PMID: 32042168 - PMCID: PMC7456461 - DOI: 10.1038/s41587-019-0404-8

Ko J, Wilkovitsch M, Oh J, Kohler RH, Bolli E, Pittet MJ, Vinegoni C, Sykes DB, Mikula H, Weissleder R, Carlson JCT

Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes Nat Biotechnol. 2022;40(11):1654-1662 - PMID: 35654978 - PMCID: PMC9669087 - DOI: 10.1038/s41587-022-01339-6

Song J, Cho MH, Cho H, Song Y, Lee SW, Nam HC, Yoon TH, Shin JC, Hong JS, Kim Y, Ekanayake E, Jeon J, You DG, Im SG, Choi GS, Park JS, Carter BC, Balaj L, Seo AN, Miller MA, Park SY, Kang T, Castro CM, Lee H

Amplifying mutational profiling of extracellular vesicle mRNA with SCOPE. Nat Biotechnol. 2024;43(9):1485-1495 - PMID: 39375445 - DOI: 10.1038/s41587-024-02426-6

Gustafsson K, Isaev S, Mirsanaye K, Hofmann J, Kooshesh KA, Baryawno N, Kiem A, Severe N, Zhao T, Scadden EW, Spencer JA, Burns C, Akilan K, Barkas N, Gessessew H, Kokkaliaris KD, Lin CP, Kharchenko PV, Scadden DT

Mesenchymal thymic niche cells enable regeneration of the adult thymus and T cell immunity. Nat Biotechnol. 2025;:ePub - PMID: 41168496 - DOI: 10.1038/s41587-025-02864-w

Lee H, Shin TH, Cheon J, Weissleder R

Recent Developments in Magnetic Diagnostic Systems Chem Rev. 2015;115(19):10690-724 - PMID: 26258867 - PMCID: PMC5791529 - DOI: 10.1021/cr500698d

Shao H, Im H, Castro CM, Breakefield X, Weissleder R, Lee H

New Technologies for Analysis of Extracellular Vesicles. Chem Rev. 2018;118(4):1917-1950 - PMID: 29384376 - PMCID: PMC6029891 - DOI: 10.1021/acs.chemrev.7b00534

Tannous B*, Grimm J*, Perry K, Chen J, Weissleder R, Breakefield X.

Metabolic Biotinylation of Cell Surface Receptors for in vivo Imaging Nat Methods. 2006;3(5):391-396 - PMID: 16628210 - DOI: 10.1038/nmeth875

Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V

In vivo imaging of Drosophila melanogaster pupae with mesoscopic fluorescence tomography. Nat Methods. 2007;5(1):45-7 - PMID: 18066071 - DOI: 10.1038/nmeth1149

Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA

A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods. 2008;5:171-173 - PMID: 18204457 - PMCID: PMC2699561 - DOI: 10.1038/nmeth.1177

Goren A, Ozsolak F, Shoresh N, Ku M, Adli M, Hart C, Gymrek M, Zuk O, Regev A, Milos PM, Bernstein BE

Chromatin profiling by directly sequencing small quantities of immunoprecipitated DNA. Nat Methods. 2009;7(1):47-9 - PMID: 19946276 - PMCID: PMC2862482 - DOI: 10.1038/nmeth.1404

Adli M, Zhu J, Bernstein BE

Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors. Nat Methods. 2010;7(8):615-8 - PMID: 20622861 - PMCID: PMC2924612 - DOI: 10.1038/nmeth.1478

Chittajallu DR, Florian S, Kohler RH, Iwamoto Y, Orth JD, Weissleder R*, Danuser G*, Mitchison TJ*

In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy Nat Methods. 2015;12(6):577-585 - PMID: 25867850 - PMCID: PMC4579269 - DOI: 10.1038/nmeth.3363

Glenn DR#, Lee K#, Park H, Weissleder R, Yacoby A, Lukin MD, Lee H*, Walsworth RL*, Connolly CB*

Single-cell magnetic imaging using a quantum diamond microscope. Nat Methods. 2015;12(8):736-738 - PMID: 26098019 - PMCID: PMC4521973 - DOI: 10.1038/nmeth.3449

Kong L, Tang J, Little JP, Yu Y, Lämmermann T, Lin CP, Germain RN, Cui M

Continuous volumetric imaging via an optical phase-locked ultrasound lens. Nat Methods. 2015;12(8):759-762 - PMID: 26167641 - PMCID: PMC4551496 - DOI: 10.1038/nmeth.3476

Haase C, Gustafsson K, Mei S, Yeh SC, Richter D, Milosevic J, Turcotte R, Kharchenko PV, Sykes DB, Scadden DT, Lin CP

Image-seq: spatially resolved single-cell sequencing guided by in situ and in vivo imaging. Nat Methods. 2022;19(12):1622-1633 - PMID: 36424441 - PMCID: PMC9718684 - DOI: 10.1038/s41592-022-01673-2

Corsten MF, Shah K

Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare. Lancet Oncol. 2008;9(4):376-84 - PMID: 18374291 - DOI: 10.1016/S1470-2045(08)70099-8

Harisinghani M

Nanoparticle-enhanced MRI: are we there yet? Lancet Oncol. 2008;9(9):814-815 - PMID: 18760237 - DOI: 10.1016/S1470-2045(08)70215-8

Khosroshahi A, Stone JR, Pratt DS, Deshpande V, Stone JH

Painless jaundice with serial multi-organ dysfunction. Lancet Oncol. 2009;373(9673):1494 - PMID: 19394539 - DOI: 10.1016/S0140-6736(09)60615-2

Herrmann K, Schwaiger M, Lewis JS, Solomon SB, McNeil BJ, Baumann M, Gambhir SS, Hricak H, Weissleder R

Radiotheranostics: a roadmap for future development Lancet Oncol. 2020;21(3):e146–56 - PMID: 32135118 - PMCID: PMC7367151 - DOI: 10.1016/S1470-2045(19)30821-6 - Cover

Shi DD, Guo JA, Hoffman HI, Su J, Mino-Kenudson M, Barth JL, Schenkel JM, Loeffler JS, Shih HA, Hong TS, Wo JY, Aguirre AJ, Jacks T, Zheng L, Wen PY, Wang TC, Hwang WL

Therapeutic avenues for cancer neuroscience: translational frontiers and clinical opportunities. Lancet Oncol. 2022;23(2):e62-e74 - PMID: 35114133 - PMCID: PMC9516432 - DOI: 10.1016/S1470-2045(21)00596-9

Hricak H, Mayerhoefer ME, Herrmann K, Lewis JS, Pomper MG, Hess CP, Riklund K , Scott AM, Weissleder R

Advances and challenges in precision imaging Lancet Oncol. 2025;26:e34-e45 - PMID: 39756454 - PMCID: PMC12117531 - DOI: 10.1016/S1470-2045(24)00395-4

Bernstock JD, Ling A, Chiocca EA

Combined gene therapies for high-grade glioma. Lancet Oncol. 2023;24(9):949-950 - PMID: 37657467 - DOI: 10.1016/S1470-2045(23)00389-3

Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA

Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis Cancer Cell. 2002;1:269-77 - PMID: 12086863 - DOI: 10.1016/s1535-6108(02)00046-6

Ji H, Li D, Chen L, Shimamura T, Kobayashi S, McNamara K, Mahmood U, Mitchell A, Sun Y, Al-Hashem R, Chirieac LR, Padera R, Bronson RT, Kim W, Janne PA, Shapiro GI, Tenen D, Johnson BE, Weissleder R, Sharpless NE, Wong KK

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell. 2006;9(6):485-95 - PMID: 16730237 - DOI: 10.1016/j.ccr.2006.04.022

Wurdinger T, Tannous BA, Saydam O, Skog J, Grau S, Soutschek J, Weissleder R, Breakefield XO, Krichevsky AM

miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells. Cancer Cell. 2008;14(5):382-393 - PMID: 18977327 - PMCID: PMC2597164 - DOI: 10.1016/j.ccr.2008.10.005

Rheinbay E, Louis DN, Bernstein BE, Suvà ML

A Tell-Tail Sign of Chromatin: Histone Mutations Drive Pediatric Glioblastoma. Cancer Cell. 2012;21(3):329-331 - PMID: 22439930 - DOI: 10.1016/j.ccr.2012.03.001

Abdel-Wahab O, Adli M, Lafave LM, Gao J, Hricik T, Shih AH, Pandey S, Patel JP, Chung YR, Koche R, Perna F, Zhao X, Taylor JE, Park CY, Carroll M, Melnick A, Nimer SD, Jaffe JD, Aifantis I, Bernstein BE, Levine RL

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression. Cancer Cell. 2012;22(2):180-93 - PMID: 22897849 - PMCID: PMC3422511 - DOI: 10.1016/j.ccr.2012.06.032

Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järås M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root DE, Scadden DT, Hynes RO, Mukherjee S, Stegmaier K, Jordan CT, Ebert BL

In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling. Cancer Cell. 2013;24(1):45-58 - PMID: 23770013 - PMCID: PMC3746037 - DOI: 10.1016/j.ccr.2013.05.004

Riggi N, Knoechel B, Gillespie SM, Rheinbay E, Boulay G, Suvà ML, Rossetti NE, Boonseng WE, Oksuz O, Cook EB, Formey A, Patel A, Gymrek M, Thapar V, Deshpande V, Ting DT, Hornicek FJ, Nielsen GP, Stamenkovic I, Aryee MJ, Bernstein BE, Rivera MN

EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma. Cancer Cell. 2014;26(5):668-81 - PMID: 25453903 - PMCID: PMC4492343 - DOI: 10.1016/j.ccell.2014.10.004

Pfirschke C, Garris C, Pittet MJ

Common TLR5 Mutations Control Cancer Progression. Cancer Cell. 2015;27(1):1-3 - PMID: 25584886 - DOI: 10.1016/j.ccell.2014.12.008

Pfirschke C, Siwicki M, Liao HW, Pittet MJ

Tumor Microenvironment: No Effector T Cells without Dendritic Cells. Cancer Cell. 2017;31(5):614-615 - PMID: 28486102 - DOI: 10.1016/j.ccell.2017.04.007

Kleppe M, Koche R, Zou L, van Galen P, Hill CE, Dong L, De Groote S, Papalexi E, Hanasoge Somasundara AV, Cordner K, Keller M, Farnoud N, Medina J, McGovern E, Reyes J, Roberts J, Witkins M, Rapaport F, Teruya-Feldstein J, Qi J, Rampal R, Bernstein BE, Bradner JE, Levine RL

Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms. Cancer Cell. 2017;33(1):29-43.e7 - PMID: 29249691 - PMCID: PMC5760343 - DOI: 10.1016/j.ccell.2017.11.009

Rahme GJ, Gaskell E, Bernstein BE

GABPβ1L Wakes Up TERT. Cancer Cell. 2018;34(3):358-360 - PMID: 30205042 - DOI: 10.1016/j.ccell.2018.08.011

Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, Bernstein BE, Alani R, Golub TR, Cole PA, Filbin MG, Shi Y

Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell. 2019;36(5):528-544.e10 - PMID: 31631026 - DOI: 10.1016/j.ccell.2019.09.005

Freed-Pastor WA, Lambert LJ, Ely ZA, Pattada NB, Bhutkar A, Eng G, Mercer KL, Garcia AP, Lin L, Rideout WM, Hwang WL, Schenkel JM, Jaeger AM, Bronson RT, Westcott PMK, Hether TD, Divakar P, Reeves JW, Deshpande V, Delorey T, Phillips D, Yilmaz OH, Regev A, Jacks T

The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer. Cancer Cell. 2021;39(10):1342-1360.e14 - PMID: 34358448 - PMCID: PMC8511341 - DOI: 10.1016/j.ccell.2021.07.007

Gong D, Arbesfeld-Qiu JM, Perrault E, Bae JW, Hwang WL

Spatial oncology: Translating contextual biology to the clinic. Cancer Cell. 2024;42(10):1653-1675 - PMID: 39366372 - PMCID: PMC12051486 - DOI: 10.1016/j.ccell.2024.09.001

Hwang WL, Perrault EN, Birbrair A, Mattson BJ, Gutmann DH, Mabbott DJ, Cukierman E, Repasky EA, Sloan EK, Zong H, Demir IE, Saloman JL, Borniger JC, Hu J, Dietrich J, Breunig JJ, Kaan Cifcibası,, K, Ahmad Kasm KA, Valiente M, Wintermark M, Acharya MM, Scheff NN, D'Silva NJ, Vermeer PD, Wong RJ, Talbot S, Hervey-Jumper SL, Wang TC, Ye Y, Pan Y, Bunimovich YL, Amit M

Integrating priorities at the intersection of cancer and neuroscience. Cancer Cell. 2024;43(1):1-5 - PMID: 39423816 - PMCID: PMC11732710 - DOI: 10.1016/j.ccell.2024.09.014

Weissleder R.

Molecular Imaging in Cancer Science. 2006;312:1168-1171 - PMID: 16728630 - DOI: 10.1126/science.1125949

Shaw S, Wang J

Knotting of a DNA chain during ring closure. Science. 1993;260(5107):533-6 - PMID: 8475384 - DOI: 10.1126/science.8475384

Sundrud MS, Koralov SB, Feuerer M, Calado DP, Kozhaya AE, Rhule-Smith A, Lefebvre RE, Unutmaz D, Mazitschek R, Waldner H, Whitman M, Keller T, Rao A

Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response. Science. 2009;324(5932):1334-1338 - PMID: 19498172 - PMCID: PMC2803727 - DOI: 10.1126/science.1172638

Swirski* FK, Nahrendorf* M, Etzrodt M, Wildgruber M, Cortez-Retamozo V, Panizzi P, Figueiredo JL, Kohler RH, Chudnovskiy A, Waterman P, Aikawa E, Mempel TR, Libby P, Weissleder R, Pittet MJ

Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites Science. 2009;325 (5940):612-6 - PMID: 19644120 - PMCID: PMC2803111 - DOI: 10.1126/science.1175202

Chi A, Bernstein B

Developmental biology. Pluripotent chromatin state. Science. 2009;323(5911):220-1 - PMID: 19131621 - PMCID: PMC4126799 - DOI: 10.1126/science.1166261

Huang D, Swanson E, Lin C, Schuman J, Stinson W, Chang W, Hee M, Flotte T, Gregory K, Puliafito C

Optical coherence tomography. Science. 1991;254:1178-81 - PMID: 1957169 - PMCID: PMC4638169 - DOI: 10.1126/science.1957169

Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A

Unbiased Reconstruction of a Mammalian Transcriptional Network Mediating Pathogen Responses. Science. 2009;326(5950):257-63 - PMID: 19729616 - PMCID: PMC2879337 - DOI: 10.1126/science.1179050

Lieberman-Aiden E, van Berkum NL, Williams L, Imakaev M, Ragoczy T, Telling A, Amit I, Lajoie BR, Sabo PJ, Dorschner MO, Sandstrom R, Bernstein B, Bender MA, Groudine M, Gnirke A, Stamatoyannopoulos J, Mirny LA, Lander ES, Dekker J

Comprehensive mapping of long-range interactions reveals folding principles of the human genome. Science. 2009;326(5950):289-93 - PMID: 19815776 - PMCID: PMC2858594 - DOI: 10.1126/science.1181369

Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D

The structure of haplotype blocks in the human genome. Science. 2002;296(5576):2225-9 - PMID: 12029063 - DOI: 10.1126/science.1069424

Rauch PJ*, Chudnovskiy A*, Robbins CS*, Weber GF, Etzrodt M, Hilgendorf I, Tiglao E, Figueiredo JL, Iwamoto Y, Theurl I, Gorbatov R, Waring MT, Chicoine AT, Mouded M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK

Innate Response Activator B Cells Protect Against Microbial Sepsis Science. 2012;335(6068):597-601 - PMID: 22245738 - PMCID: PMC3279743 - DOI: 10.1126/science.1215173

Ryan RJ, Bernstein BE

Molecular biology. Genetic events that shape the cancer epigenome. Science. 2012;336(6088):1513-4 - PMID: 22723401 - DOI: 10.1126/science.1223730

Swirski FK, Nahrendorf M

Leukocyte behavior in atherosclerosis, myocardial infarction, and heart failure. Science. 2013;339(6116):161-6 - PMID: 23307733 - PMCID: PMC3891792 - DOI: 10.1126/science.1230719

Suvà ML, Riggi N, Bernstein BE

Epigenetic reprogramming in cancer. Science. 2013;339(6127):1567-70 - PMID: 23539597 - PMCID: PMC3821556 - DOI: 10.1126/science.1230184

Viaud S, Saccheri F, Mignot G, Yamazaki T, Daillère R, Hannani D, Enot DP, Pfirschke C, Engblom C, Pittet MJ, Schlitzer A, Ginhoux F, Apetoh L, Chachaty E, Woerther PL, Eberl G, Bérard M, Ecobichon C, Clermont D, Bizet C, Gaboriau-Routhiau V, Cerf-Bensussan N, Opolon P, Yessaad N, Vivier E, Ryffel B, Elson CO, Doré J, Kroemer G, Lepage P, Boneca IG, Ghiringhelli F, Zitvogel L

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide. Science. 2013;342(6161):971-6 - PMID: 24264990 - PMCID: PMC4048947 - DOI: 10.1126/science.1240537

Katsimpardi L, Litterman NK, Schein PA, Miller CM, Loffredo FS, Wojtkiewicz GR, Chen JW, Lee RT, Wagers AJ, Rubin LL

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors. Science. 2014;344(6184):630-4 - PMID: 24797482 - PMCID: PMC4123747 - DOI: 10.1126/science.1251141

Patel AP, Tirosh I, Trombetta JJ, Shalek AK, Gillespie SM, Wakimoto H, Cahill DP, Nahed BV, Curry WT, Martuza RL, Louis DN, Rozenblatt-Rosen O, Suvà ML, Regev A, Bernstein BE

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma. Science. 2014;344(6190):1396-401 - PMID: 24925914 - PMCID: PMC4123637 - DOI: 10.1126/science.1254257

Weber GF, Chousterman BG, He S, Fenn AM, Nairz M, Anzai A, Brenner T, Uhle F, Iwamoto Y, Robbins CS, Noiret L, Maier SL, Zönnchen T, Rahbari NN, Schölch S, Klotzsche-von Ameln A, Chavakis T, Weitz J, Hofer S, Weigand MA, Nahrendorf M, Weissleder R, Swirski FK

Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis. Science. 2015;347(6227):1260-1265 - PMID: 25766237 - PMCID: PMC4376966 - DOI: 10.1126/science.aaa4268

Nahrendorf M, Swirski FK

Neutrophil-macrophage communication in inflammation and atherosclerosis. Science. 2015;349(6245):237-8 - PMID: 26185231 - DOI: 10.1126/science.aac7801

Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, Alvarez D, Sprachman M, Evavold C, Magnuson A, von Andrian UH, Glatz K, Breakefield XO, Mempel TR, Weissleder R, Pittet MJ

SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions Science. 2016;352(6282):242-246 - PMID: 26989197 - PMCID: PMC4960636 - DOI: 10.1126/science.aaf1328

Shema E, Jones D, Shoresh N, Donohue L, Ram O, Bernstein BE

Single-molecule decoding of combinatorially modified nucleosomes. Science. 2016;352(6286):717-21 - PMID: 27151869 - PMCID: PMC4904710 - DOI: 10.1126/science.aad7701

Ito K, Turcotte R, Cui J, Zimmerman SE, Pinho S, Mizoguchi T, Arai F, Runnels JM, Alt C, Teruya-Feldstein J, Mar JC, Singh R, Suda T, Lin CP, Frenette PS, Ito K

Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance. Science. 2016;354(6316):1156-1160 - PMID: 27738012 - PMCID: PMC5164878 - DOI: 10.1126/science.aaf5530

Venteicher AS, Tirosh I, Hebert C, Yizhak K, Neftel C, Filbin MG, Hovestadt V, Escalante LE, Shaw ML, Rodman C, Gillespie SM, Dionne D, Luo CC, Ravichandran H, Mylvaganam R, Mount C, Onozato ML, Nahed BV, Wakimoto H, Curry WT, Iafrate AJ, Rivera MN, Frosch MP, Golub TR, Brastianos PK, Getz G, Patel AP, Monje M, Cahill DP, Rozenblatt-Rosen O, Louis DN, Bernstein BE, Regev A, Suvà ML

Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq. Science. 2017;355(6332):ePub - PMID: 28360267 - PMCID: PMC5519096 - DOI: 10.1126/science.aai8478

Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK

Origins of lymphatic and distant metastases in human colorectal cancer. Science. 2017;357(6346):55-60 - PMID: 28684519 - PMCID: PMC5536201 - DOI: 10.1126/science.aai8515

Flavahan WA, Gaskell E, Bernstein BE

Epigenetic plasticity and the hallmarks of cancer. Science. 2017;357(6348):ePub - PMID: 28729483 - PMCID: PMC5940341 - DOI: 10.1126/science.aal2380

Engblom C*, Pfirschke C*, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ

Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils Science. 2017;358:eaal5081 - PMID: 29191879 - PMCID: PMC6343476 - DOI: 10.1126/science.aal5081

Filbin MG, Tirosh I, Hovestadt V, Shaw ML, Escalante LE, Mathewson ND, Neftel C, Frank N, Pelton K, Hebert CM, Haberler C, Yizhak K, Gojo J, Egervari K, Mount C, van Galen P, Bonal DM, Nguyen QD, Beck A, Sinai C, Czech T, Dorfer C, Goumnerova L, Lavarino C, Carcaboso AM, Mora J, Mylvaganam R, Luo CC, Peyrl A, Popović M, Azizi A, Batchelor TT, Frosch MP, Martinez-Lage M, Kieran MW, Bandopadhayay P, Beroukhim R, Fritsch G, Getz G, Rozenblatt-Rosen O, Wucherpfennig KW, Louis DN, Monje M, Slavc I, Ligon KL, Golub TR, Regev A, Bernstein BE, Suvà ML

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq. Science. 2018;360(6386):331-335 - PMID: 29674595 - PMCID: PMC5949869 - DOI: 10.1126/science.aao4750

Choi SH, Bylykbashi E, Chatila ZK, Lee SW, Pulli B, Clemenson GD, Kim E, Rompala A, Oram MK, Asselin C, Aronson J, Zhang C, Miller SJ, Lesinski A, Chen JW, Kim DY, van Praag H, Spiegelman BM, Gage FH, Tanzi RE

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model. Science. 2018;361(6406):ePub - PMID: 30190379 - PMCID: PMC6149542 - DOI: 10.1126/science.aan8821

Hulsmans M, Schloss MJ, Lee IH, Bapat A, Iwamoto Y, Vinegoni C, Paccalet A, Yamazoe M, Grune J, Pabel S, Momin N, Seung H, Kumowski N, Pulous FE, Keller D, Bening C, Green U, Lennerz JK, Mitchell RN, Lewis A, Casadei B, Iborra-Egea O, Bayes-Genis A, Sossalla S, Ong CS, Pierson RN, Aster JC, Rohde D, Wojtkiewicz GR, Weissleder R, Swirski FK, Tellides G, Tolis G, Melnitchouk S, Milan DJ, Ellinor PT, Naxerova K, Nahrendorf M

Recruited macrophages elicit atrial fibrillation. Science. 2023;381(6654):231-239 - PMID: 37440641 - PMCID: PMC10448807 - DOI: 10.1126/science.abq3061

Bill R, Wirapati P, Messemaker M, Roh W, Zitti B, Duval F, Kiss M, Park JC, Saal TM, Hoelzl J, Tarussio D, Benedetti F, Tissot S, Kandalaft L, Varrone M, Ciriello G, McKee TA, Monnier Y, Mermod M, Blaum EM, Gushterova I, Gonye ALK, Hacohen N, Getz G, Mempel TR, Klein AM, Weissleder R, Faquin WC, Sadow PM, Lin D, Pai SI, Sade-Feldman M, Pittet MJ

CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers. Science. 2023;381(6657):515-524 - PMID: 37535729 - PMCID: PMC10755760 - DOI: 10.1126/science.ade2292

Pessoa Rodrigues C, Collins JM, Yang S, Martinez C, Kim JW, Lama C, Nam AS, Alt C, Lin C, Zon LI

Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells. Science. 2024;385(6714):eadn1629 - PMID: 39264994 - PMCID: PMC12012832 - DOI: 10.1126/science.adn1629

Nahrendorf M, Ginhoux F, Swirski FK

Immune system influence on physiology. Science. 2025;389(6760):594-599 - PMID: 40773571 - PMCID: PMC12629239 - DOI: 10.1126/science.adx4380

Kumowski N, Pabel S, Grune J, Momin N, Ninh VK, Stengel L, Mentkowski KI, Iwamoto Y, Zheng Y, Lee IH, Matthias J, Wirth JO, Pulous FE, Seung H, Paccalet A, Muse CG, Ting KKY, Delgado P, Lewis AJM, Kaushal V, Kreso A, Brown D, Hayat S, Kramann R, Swirski FK, Naxerova K, Propheter DC, Hooper LV, Moskowitz MA, King KR, Rosenthal N, Hulsmans M, Nahrendorf M

Resistin-like molecule γ attacks cardiomyocyte membranes and promotes ventricular tachycardia. Science. 2025;389(6764):1043-1048 - PMID: 40906843 - DOI: 10.1126/science.adp7361

Tawakol A, Ishai A, Takx RA, Figueroa AL, Ali A, Kaiser Y, Truong QA, Solomon CJ, Calcagno C, Mani V, Tang CY, Mulder WJ, Murrough JW, Hoffmann U, Nahrendorf M, Shin LM, Fayad ZA, Pitman RK

Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study. Lancet. 2017;389(10071):834-845 - PMID: 28088338 - PMCID: PMC7864285 - DOI: 10.1016/S0140-6736(16)31714-7

Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D

Arthritis critically dependent on innate immune system players Immunity. 2002;16:157-68 - PMID: 11869678 - DOI: 10.1016/s1074-7613(02)00275-3

Mempel T, Pittet M, Khazaie K, Weninger W, Weissleder R, von Boehmer H, von Adrian U.

Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation Immunity. 2006;25(1):129-41 - PMID: 16860762 - DOI: 10.1016/j.immuni.2006.04.015

Cortez-Retamozo V, Etzrodt M, Newton A, Ryan R, Pucci F, Sio SW, Kuswanto W, Rauch PJ, Chudnovskiy A, Iwamoto Y, Kohler R, Marinelli B, Gorbatov R, Wojtkiewicz G, Panizzi P, Mino-Kenudson M, Forghani R, Figueiredo JL, Chen JW, Xavier R, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ

Angiotensin II Drives the Production of Tumor-Promoting Macrophages Immunity. 2013;38(2):296-308 - PMID: 23333075 - PMCID: PMC3582771 - DOI: 10.1016/j.immuni.2012.10.015

Bronte V, Pittet MJ

The spleen in local and systemic regulation of immunity. Immunity. 2013;39(5):806-18 - PMID: 24238338 - PMCID: PMC3912742 - DOI: 10.1016/j.immuni.2013.10.010

Pfirschke C, Engblom C, Rickelt S, Cortez-Retamozo V, Garris C, Pucci F, Yamasaki T, Poirier-Colame V, Newton A, Redouane Y, Lin YJ, Wojtkiewicz G, Iwamoto Y, Mino-Kenudson M, Huynh TG, Hynes RO, Freeman GJ Kroemer G, Zitvogel L, Weissleder R, Pittet MJ

Immunogenic Chemotherapy Sensitizes Tumors to Checkpoint Blockade Therapy Immunity. 2016;44:1-12 - PMID: 26872698 - PMCID: PMC4758865 - DOI: 10.1016/j.immuni.2015.11.024

Schloss MJ, Nahrendorf M

Some Macrophages Are Softies. Immunity. 2018;49(2):199-201 - PMID: 30134196 - DOI: 10.1016/j.immuni.2018.08.007

Braza MS, van Leent MMT, Lameijer M, Sanchez-Gaytan BL, Arts RJW, Pérez-Medina C, Conde P, Garcia MR, Gonzalez-Perez M, Brahmachary M, Fay F, Kluza E, Kossatz S, Dress RJ, Salem F, Rialdi A, Reiner T, Boros P, Strijkers GJ, Calcagno CC, Ginhoux F, Marazzi I, Lutgens E, Nicolaes GAF, Weber C, Swirski FK, Nahrendorf M, Fisher EA, Duivenvoorden R, Fayad ZA, Netea MG, Mulder WJM, Ochando J

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance. Immunity. 2018;49(5):819-828.e6 - PMID: 30413362 - PMCID: PMC6251711 - DOI: 10.1016/j.immuni.2018.09.008

Garris CS*, Arlauckas SP*, Kohler RH, Trefny MP, Garren S, Piot C, Engblom C, Pfirschke C, Siwicki M, Gungabeesoon J, Freeman GJ, Warren SE, Ong S, Browning E, Twitty CG, Pierce RH, Le MH, Algazi AP, Daud AI, Pai SI, Zippelius A, Weissleder R, Pittet MJ

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12 Immunity. 2018;49:1-14 - PMID: 30552023 - PMCID: PMC6301092 - DOI: 10.1016/j.immuni.2018.09.024

Zilionis R*, Engblom C*, Pfirschke C, Savova V, Zemmour D, Saatcioglu HD, Krishnan I, Maroni G, Meyerovitz CV, Kerwin CM, Choi S, Richards WG, De Rienzo A, Tenen DG, Bueno R, Levantini E, Pittet MJ**, Klein AM**

Single-Cell Transcriptomics of Human and Mouse Lung Cancers Reveals Conserved Myeloid Populations across Individuals and Species. Immunity. 2019;50(5):1317-1334.e10 - PMID: 30979687 - PMCID: PMC6620049 - DOI: 10.1016/j.immuni.2019.03.009

Hoyer FF*, Naxerova K*, Schloss MJ, Hulsmans M, Nair AV, Dutta P, Calcagno DM, Herisson F, Anzai A, Sun Y, Wojtkiewicz G, Rohde D, Frodermann V, Vandoorne K, Courties G, Iwamoto Y, Garris CS, Williams DL, Breton S, Brown D, Whalen M, Libby P, Pittet MJ, King KR, Weissleder R, Swirski FK, Nahrendorf M

Tissue-Specific Macrophage Responses to Remote Injury Impact the Outcome of Subsequent Local Immune Challenge. Immunity. 2019;51(5):899-914.e7 - PMID: 31732166 - PMCID: PMC6892583 - DOI: 10.1016/j.immuni.2019.10.010

Bajpai G, Nahrendorf M

Infectious and lifestyle modifiers of immunity and host resilience. Immunity. 2021;54(6):1110-1122 - PMID: 34107270 - DOI: 10.1016/j.immuni.2021.05.011

Schenkel JM, Herbst RH, Canner D, Li A, Hillman M, Shanahan SL, Gibbons G, Smith OC, Kim JY, Westcott P, Hwang WL, Freed-Pastor WA, Eng G, Cuoco MS, Rogers P, Park JK, Burger ML, Rozenblatt-Rosen O, Cong L, Pauken KE, Regev A, Jacks T

Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes. Immunity. 2021;54(10):2338-2353.e6 - PMID: 34534439 - PMCID: PMC8604155 - DOI: 10.1016/j.immuni.2021.08.026

Zagorulya M, Yim L, Morgan DM, Edwards A, Torres-Mejia E, Momin N, McCreery CV, Zamora IL, Horton BL, Fox JG, Wittrup KD, Love JC, Spranger S

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer. Immunity. 2023;56(2):386-405.e10 - PMID: 36736322 - PMCID: PMC10880816 - DOI: 10.1016/j.immuni.2023.01.010

Janssen H, Kahles F, Liu D, Downey J, Koekkoek LL, Roudko V, D'Souza D, McAlpine CS, Halle L, Poller WC, Chan CT, He S, Mindur JE, Kiss MG, Singh S, Anzai A, Iwamoto Y, Kohler RH, Chetal K, Sadreyev RI, Weissleder R, Kim-Schulze S, Merad M, Nahrendorf M, Swirski FK

Monocytes re-enter the bone marrow during fasting and alter the host response to infection. Immunity. 2023;56(4):783-796.e7 - PMID: 36827982 - PMCID: PMC10101885 - DOI: 10.1016/j.immuni.2023.01.024

Kiss MG, Mindur JE, Yates AG, Lee D, Fullard JF, Anzai A, Poller WC, Christie KA, Iwamoto Y, Roudko V, Downey J, Chan CT, Huynh P, Janssen H, Ntranos A, Hoffmann JD, Jacob W, Goswami S, Singh S, Leppert D, Kuhle J, Kim-Schulze S, Nahrendorf M, Kleinstiver BP, Probert F, Roussos P, Swirski FK, McAlpine CS

Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis. Immunity. 2023;56(7):1502-1514.e8 - PMID: 37160117 - PMCID: PMC10524830 - DOI: 10.1016/j.immuni.2023.04.013

Pittet MJ, Di Pilato M, Garris C, Mempel TR

Dendritic cells as shepherds of T cell immunity in cancer. Immunity. 2023;56(10):2218-2230 - PMID: 37708889 - PMCID: PMC10591862 - DOI: 10.1016/j.immuni.2023.08.014

Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005;37(7):739-44 - PMID: 15924139 - PMCID: PMC1360984 - DOI: 10.1038/ng1592

Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006;38(5):531-9 - PMID: 16604073 - DOI: 10.1038/ng1777

Andriopoulos Jr B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet. 2009;41(4):482-7 - PMID: 19252486 - PMCID: PMC2810136 - DOI: 10.1038/ng.335

Reich DE, Schaffner SF, Daly MJ, McVean G, Mullikin JC, Higgins JM, Richter DJ, Lander ES, Altshuler D

Human genome sequence variation and the influence of gene history, mutation and recombination. Nat Genet. 2002;32(1):135-42 - PMID: 12161752 - DOI: 10.1038/ng947

Knoechel B, Roderick JE, Williamson KE, Zhu J, Lohr JG, Cotton MJ, Gillespie SM, Fernandez D, Ku M, Wang H, Piccioni F, Silver SJ, Jain M, Pearson D, Kluk MJ, Ott CJ, Shultz LD, Brehm MA, Greiner DL, Gutierrez A, Stegmaier K, Kung AL, Root DE, Bradner JE, Aster JC, Kelliher MA, Bernstein BE

An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemia. Nat Genet. 2014;46(4):364-70 - PMID: 24584072 - PMCID: PMC4086945 - DOI: 10.1038/ng.2913

Drier Y, Cotton MJ, Williamson KE, Gillespie SM, Ryan RJ, Kluk MJ, Carey CD, Rodig SJ, Sholl LM, Afrogheh AH, Faquin WC, Queimado L, Qi J, Wick MJ, El-Naggar AK, Bradner JE, Moskaluk CA, Aster JC, Knoechel B, Bernstein BE

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma. Nat Genet. 2016;48(3):265-72 - PMID: 26829750 - PMCID: PMC4767593 - DOI: 10.1038/ng.3502

Wang X, Lee RS, Alver BH, Haswell JR, Wang S, Mieczkowski J, Drier Y, Gillespie SM, Archer TC, Wu JN, Tzvetkov EP, Troisi EC, Pomeroy SL, Biegel JA, Tolstorukov MY, Bernstein BE, Park PJ, Roberts CW

SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation. Nat Genet. 2016;49(2):289-295 - PMID: 27941797 - PMCID: PMC5285474 - DOI: 10.1038/ng.3746

Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S, , Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types. Nat Genet. 2018;50(4):621-629 - PMID: 29632380 - PMCID: PMC5896795 - DOI: 10.1038/s41588-018-0081-4

Shema E, Bernstein BE, Buenrostro JD

Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution. Nat Genet. 2018;51(1):19-25 - PMID: 30559489 - DOI: 10.1038/s41588-018-0290-x

Naxerova K

Clonal competition in a confined space. Nat Genet. 2020;52(6):553-554 - PMID: 32424354 - DOI: 10.1038/s41588-020-0638-x

Reiter JG, Hung WT, Lee IH, Nagpal S, Giunta P, Degner S, Liu G, Wassenaar ECE, Jeck WR, Taylor MS, Farahani AA, Marble HD, Knott S, Kranenburg O, Lennerz JK, Naxerova K

Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases. Nat Genet. 2020;52(7):692-700 - PMID: 32451459 - PMCID: PMC7343611 - DOI: 10.1038/s41588-020-0633-2

Hwang WL, Jagadeesh KA, Guo JA, Hoffman HI, Yadollahpour P, Reeves JW, Mohan R, Drokhlyansky E, Van Wittenberghe N, Ashenberg O, Farhi SL, Schapiro D, Divakar P, Miller E, Zollinger DR, Eng G, Schenkel JM, Su J, Shiau C, Yu P, Freed-Pastor WA, Abbondanza D, Mehta A, Gould J, Lambden C, Porter CBM, Tsankov A, Dionne D, Waldman J, Cuoco MS, Nguyen L, Delorey T, Phillips D, Barth JL, Kem M, Rodrigues C, Ciprani D, Roldan J, Zelga P, Jorgji V, Chen JH, Ely Z, Zhao D, Fuhrman K, Fropf R, Beechem JM, Loeffler JS, Ryan DP, Weekes CD, Ferrone CR, Qadan M, Aryee MJ, Jain RK, Neuberg DS, Wo JY, Hong TS, Xavier R, Aguirre AJ, Rozenblatt-Rosen O, Mino-Kenudson M, Castillo CF, Liss AS, Ting DT, Jacks T, Regev A

Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment. Nat Genet. 2022;54(8):1178-1191 - PMID: 35902743 - PMCID: PMC10290535 - DOI: 10.1038/s41588-022-01134-8 - Cover

Shiau C, Cao J, Gong D, Gregory MT, Caldwell NJ, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Bae JW, Zhao R, Schurman N, Barth JL, Ganci ML, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Castillo CF, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL

Spatially resolved analysis of pancreatic cancer identifies therapy-associated remodeling of the tumor microenvironment. Nat Genet. 2024;56(11):2466-2478 - PMID: 39227743 - PMCID: PMC11816915 - DOI: 10.1038/s41588-024-01890-9

Blohmer M, Cheek DM, Hung WT, Kessler M, Chatzidimitriou F, Wang J, Hung W, Lee IH, Gorelick AN, Wassenaar EC, Yang CY, Yeh YC, Ho HL, Speiser D, Karsten MM, Lanuti M, Pai SI, Kranenburg O, Lennerz JK, Chou TY, Kloor M, Naxerova K

Quantifying cell divisions along evolutionary lineages in cancer. Nat Genet. 2025;57(3):706-717 - PMID: 39905260 - DOI: 10.1038/s41588-025-02078-5

Zhou VW, Goren A, Bernstein BE

Charting histone modifications and the functional organization of mammalian genomes. Nat Rev Genet. 2010;12(1):7-18 - PMID: 21116306 - DOI: 10.1038/nrg2905

Swirski FK, Nahrendorf M

Cardioimmunology: the immune system in cardiac homeostasis and disease. Nat Rev Immunol. 2018;18(12):733-744 - PMID: 30228378 - DOI: 10.1038/s41577-018-0065-8

Swirski FK, Nahrendorf M

Reply to 'Cardioimmunology of arrhythmias: the role of autoimmune and inflammatory cardiac channelopathies'. Nat Rev Immunol. 2019;19(1):65 - PMID: 30552386 - DOI: 10.1038/s41577-018-0099-y

Stoeck A, Lejnine S, Truong A, Pan L, Wang H, Zang C, Yuan J, Ware C, MacLean J, Garrett-Engele PW, Kluk M, Laskey J, Haines BB, Moskaluk C, Zawel L, Fawell S, Gilliland G, Zhang T, Kremer B, Knoechel B, Bernstein BE, Pear WS, Liu XS, Aster JC, Sathyanarayanan S

Discovery of biomarkers predictive of GSI response in triple negative breast cancer and adenoid cystic carcinoma. Cancer Discov. 2014;4(10):1154-67 - PMID: 25104330 - PMCID: PMC4184927 - DOI: 10.1158/2159-8290.CD-13-0830

Ryan RJ, Drier Y, Whitton H, Cotton MJ, Kaur J, Issner R, Gillespie S, Epstein CB, Nardi V, Sohani AR, Hochberg EP, Bernstein BE

Detection of Enhancer-Associated Rearrangements Reveals Mechanisms of Oncogene Dysregulation in B-cell Lymphoma. Cancer Discov. 2015;5(10):1058-71 - PMID: 26229090 - PMCID: PMC4592453 - DOI: 10.1158/2159-8290.CD-15-0370

Miller MA, Oudin MJ, Sullivan RJ, Wang SJ, Meyer AS, Im H, Frederick DT, Tadros J, Griffith LG, Lee H, Weissleder R, Flaherty KT, Gertler FB, Lauffenburger DA

Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance. Cancer Discov. 2016;6(4):382-99 - PMID: 26984351 - PMCID: PMC5087317 - DOI: 10.1158/2159-8290.CD-15-0933

Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, Raulet DH, Weinberg RA

Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells. Cancer Discov. 2016;6(6):630-49 - PMID: 27072748 - PMCID: PMC4918202 - DOI: 10.1158/2159-8290.CD-15-1157

Goyal L, Saha SK, Liu LY, Siravegna G, Leshchiner I, Ahronian LG, Lennerz JK, Vu P, Deshpande V, Kambadakone A, Mussolin B, Reyes S, Henderson L, Sun JE, Van Seventer EE, Gurski JM, Baltschukat S, Schacher-Engstler B, Barys L, Stamm C, Furet P, Ryan DP, Stone JR, Iafrate AJ, Getz G, Graus Porta D, Tiedt R, Bardelli A, Juric D, Corcoran RB, Bardeesy N, Zhu AX

Polyclonal Secondary FGFR2 Mutations Drive Acquired Resistance to FGFR Inhibition in Patients with FGFR2 Fusion-Positive Cholangiocarcinoma. Cancer Discov. 2016;7(3):252-263 - PMID: 28034880 - PMCID: PMC5433349 - DOI: 10.1158/2159-8290.CD-16-1000

Kato S, Weng QY, Insco ML, Chen KY, Muralidhar S, Pozniak J, Diaz JMS, Drier Y, Nguyen N, Lo JA, van Rooijen E, Kemeny LV, Zhan Y, Feng Y, Silkworth W, Powell CT, Liau BB, Xiong Y, Jin J, Newton-Bishop J, Zon LI, Bernstein BE, Fisher DE

Gain-of-function genetic alterations of G9a drive oncogenesis. Cancer Discov. 2020;10(7):980-997 - PMID: 32269030 - PMCID: PMC7334057 - DOI: 10.1158/2159-8290.CD-19-0532

Bianchi A, De Castro Silva I, Deshpande NU, Singh S, Mehra S, Garrido VT, Guo X, Nivelo LA, Kolonias DS, Saigh SJ, Wieder E, Rafie CI, Dosch AR, Zhou Z, Umland O, Amirian H, Ogobuiro IC, Zhang J, Ban Y, Shiau C, Nagathihalli NS, Montgomery EA, Hwang WL, Brambilla R, Komanduri K, Villarino AV, Toska E, Stanger BZ, Gabrilovich DI, Merchant NB, Datta J

Cell-autonomous Cxcl1 sustains tolerogenic circuitries and stromal inflammation via neutrophil-derived TNF in pancreatic cancer. Cancer Discov. 2023;13(6):1428-1453 - PMID: 36946782 - PMCID: PMC10259764 - DOI: 10.1158/2159-8290.CD-22-1046

Nahrendorf M, Aikawa E, Figueiredo JL, Stangenberg L, van den Borne S, Blankesteijn M, Sosnovik D, Jaffer F, Tung CH, Weissleder R

Transglutaminase activity in acute infarcts predicts healing outcome and let ventricular remodelling : implications for FXIII therapy and antithrombin use in myocardial infarction Eur Heart J. 2008;29:445-454 - PMID: 18276618 - DOI: 10.1093/eurheartj/ehm558

Matter CM, Stuber M, Nahrendorf M

Imaging of the unstable plaque: how far have we got? Eur Heart J. 2009;30(21):2566-74 - PMID: 19833636 - PMCID: PMC2771148 - DOI: 10.1093/eurheartj/ehp419

Hjortnaes J, Butcher J, Figueiredo JL, Riccio M, Kohler RH, Kozloff KM, Weissleder R, Aikawa E

Arterial and aortic valve calcification inversely correlates with osteoporotic bone remodelling: a role for inflammation. Eur Heart J. 2010;31(16):1975-84 - PMID: 20601388 - PMCID: PMC2921509 - DOI: 10.1093/eurheartj/ehq237

van der Laan AM, Ter Horst EN, Delewi R, Begieneman MP, Krijnen PA, Hirsch A, Lavaei M, Nahrendorf M, Horrevoets AJ, Niessen HW, Piek JJ

Monocyte subset accumulation in the human heart following acute myocardial infarction and the role of the spleen as monocyte reservoir. Eur Heart J. 2013;35(6):376-85 - PMID: 23966310 - PMCID: PMC3916776 - DOI: 10.1093/eurheartj/eht331

Amabile N, Cheng S, Renard JM, Larson MG, Ghorbani A, McCabe E, Griffin G, Guerin C, Ho JE, Shaw SY, Cohen KS, Vasan RS, Tedgui A, Boulanger CM, Wang TJ

Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study. Eur Heart J. 2014;35(42):2972-9 - PMID: 24742886 - PMCID: PMC4223610 - DOI: 10.1093/eurheartj/ehu153

Leuschner F, Courties G, Dutta P, Mortensen LJ, Gorbatov R, Sena B, Novobrantseva TI, Borodovsky A, Fitzgerald K, Koteliansky V, Iwamoto Y, Bohlender M, Meyer S, Lasitschka F, Meder B, Katus HA, Lin C, Libby P, Swirski FK, Anderson DG, Weissleder R, Nahrendorf M

Silencing of CCR2 in myocarditis. Eur Heart J. 2014;36(23):1478-88 - PMID: 24950695 - PMCID: PMC4465633 - DOI: 10.1093/eurheartj/ehu225

Nahrendorf M, Swirski FK

Innate immune cells in ischaemic heart disease: does myocardial infarction beget myocardial infarction Eur Heart J. 2015;37(11):868-72 - PMID: 26351395 - PMCID: PMC4789592 - DOI: 10.1093/eurheartj/ehv453

Hara T, Ughi GJ, McCarthy JR, Erdem SS, Mauskapf A, Lyon SC, Fard AM, Edelman ER, Tearney GJ, Jaffer FA

Intravascular fibrin molecular imaging improves the detection of unhealed stents assessed by optical coherence tomography in vivo. Eur Heart J. 2015;38(6):447-455 - PMID: 26685129 - PMCID: PMC5837565 - DOI: 10.1093/eurheartj/ehv677

van der Valk FM, Kuijk C, Verweij SL, Stiekema LC, Kaiser Y, Zeerleder S, Nahrendorf M, Voermans C, Stroes ES

Increased haematopoietic activity in patients with atherosclerosis. Eur Heart J. 2017;38(6):425-432 - PMID: 27357356 - DOI: 10.1093/eurheartj/ehw246

Frodermann V, Nahrendorf M

Neutrophil-macrophage cross-talk in acute myocardial infarction. Eur Heart J. 2017;38(3):198-200 - PMID: 28158564 - PMCID: PMC5837392 - DOI: 10.1093/eurheartj/ehw085

Nahrendorf M, Swirski FK

Cholesterol, CCR2, and monocyte phenotypes in atherosclerosis. Eur Heart J. 2017;38(20):1594-1596 - PMID: 28329093 - DOI: 10.1093/eurheartj/ehx098

Hoyer FF, Nahrendorf M

Neutrophil contributions to ischaemic heart disease. Eur Heart J. 2017;38(7):465-472 - PMID: 28363210 - DOI: 10.1093/eurheartj/ehx017

Hoogeveen RM, Nahrendorf M, Riksen NP, Netea MG, de Winther MPJ, Lutgens E, Nordestgaard B, Neidhart M, Stroes ESG, Catapano AL, Bekkering S

Monocyte and haematopoietic progenitor reprogramming as common mechanism underlying chronic inflammatory and cardiovascular diseases. Eur Heart J. 2018;39(38):3521-3527 - PMID: 29069365 - PMCID: PMC6174026 - DOI: 10.1093/eurheartj/ehx581

Yvan-Charvet L, Swirski FK

Is defective cholesterol efflux an integral inflammatory component in myelopoiesis-driven cardiovascular diseases? Eur Heart J. 2018;39(23):2168-2171 - PMID: 29771312 - DOI: 10.1093/eurheartj/ehy269

Vromman A, Ruvkun V, Shvartz E, Wojtkiewicz G, Santos Masson G, Tesmenitsky Y, Folco E, Gram H, Nahrendorf M, Swirski FK, Sukhova GK, Libby P

Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis. Eur Heart J. 2019;40(30):2482-2491 - PMID: 30698710 - PMCID: PMC6685323 - DOI: 10.1093/eurheartj/ehz008

Leuschner F, Nahrendorf M

Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction. Eur Heart J. 2020;41(9):989-994 - PMID: 30945736 - PMCID: PMC7778432 - DOI: 10.1093/eurheartj/ehz159

Rohde D, Nahrendorf M

Clonal and diverse: revisiting cardiac endothelial cells after myocardial infarction. Eur Heart J. 2019;40(30):2521-2522 - PMID: 31162523 - PMCID: PMC6685322 - DOI: 10.1093/eurheartj/ehz375

Swirski FK

ESC William Harvey Lecture on Basic Science 2020. Eur Heart J. 2020;41(46):4373-4374 - PMID: 33349865 - DOI: 10.1093/eurheartj/ehaa766

Hinterdobler J, Schott S, Jin H, Meesmann A, Steinsiek AL, Zimmermann AS, Wobst J, Müller P, Mauersberger C, Vilne B, Baecklund A, Chen CS, Moggio A, Braster Q, Molitor M, Krane M, Kempf WE, Ladwig KH, Hristov M, Hulsmans M, Hilgendorf I, Weber C, Wenzel P, Scheiermann C, Maegdefessel L, Soehnlein O, Libby P, Nahrendorf M, Schunkert H, Kessler T, Sager HB

Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis. Eur Heart J. 2021;42(39):4077-4088 - PMID: 34279021 - PMCID: PMC8516477 - DOI: 10.1093/eurheartj/ehab371

Stiekema LCA, Willemsen L, Kaiser Y, Prange KHM, Wareham NJ, Boekholdt SM, Kuijk C, de Winther MPJ, Voermans C, Nahrendorf M, Stroes ESG, Kroon J

Impact of cholesterol on proinflammatory monocyte production by the bone marrow. Eur Heart J. 2021;42(42):4309-4320 - PMID: 34343254 - PMCID: PMC8572558 - DOI: 10.1093/eurheartj/ehab465

Steffens S, Nahrendorf M, Madonna R

Immune cells in cardiac homeostasis and disease: emerging insights from novel technologies. Eur Heart J. 2021;43(16):1533-1541 - PMID: 34897403 - PMCID: PMC9020986 - DOI: 10.1093/eurheartj/ehab842

Libby P, Nahrendorf M, Swirski FK

Mischief in the marrow: a root of cardiovascular evil. Eur Heart J. 2022;43(19):1829-1831 - PMID: 35567561 - DOI: 10.1093/eurheartj/ehac149

Clauss S, Nahrendorf M, Kääb S

Leducq-funded programme: immune targets for the treatment of atrial fibrillation. Eur Heart J. 2025;46(25):2369-2371 - PMID: 40326349 - DOI: 10.1093/eurheartj/ehaf176

Rabin O, Manuel Perez J, Grimm J, Wojtkiewicz G, Weissleder R

An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nat Mater. 2006;5(2):118-22 - PMID: 16444262 - DOI: 10.1038/nmat1571

Weissleder R, Nahrendorf M, Pittet MJ

Imaging macrophages with nanoparticles. Nat Mater. 2014;13(2):125-38 - PMID: 24452356 - DOI: 10.1038/nmat3780

Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM, Farokhzad OC, Mahmoudi M

Cellular uptake of nanoparticles: journey inside the cell. Chem Soc Rev. 2017;46(14):4218-4244 - PMID: 28585944 - PMCID: PMC5593313 - DOI: 10.1039/c6cs00636a

Marten K, Bremer C, Khazaie K, Sameni M, Sloane B, Tung CH, Weissleder R

Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice Gastroenterology. 2002;122:406-14 - PMID: 11832455 - DOI: 10.1053/gast.2002.30990

Mahmood U, Wallace MB

Molecular imaging in gastrointestinal disease. Gastroenterology. 2007;132(1):11-4 - PMID: 17241854 - DOI: 10.1053/j.gastro.2006.12.013

Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity. Gastroenterology. 2008;134(4):1028-37 - PMID: 18395084 - DOI: 10.1053/j.gastro.2008.01.070

Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B, Lin HY, Pietrangelo A, Babitt JL

Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis. Gastroenterology. 2009;137(4):1489-97 - PMID: 19591830 - PMCID: PMC2757523 - DOI: 10.1053/j.gastro.2009.06.057

Corradini E, Schmidt PJ, Meynard D, Garuti C, Montosi G, Chen S, Vukicevic S, Pietrangelo A, Lin HY, Babitt JL

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice. Gastroenterology. 2010;139(5):1721-9 - PMID: 20682319 - PMCID: PMC3295242 - DOI: 10.1053/j.gastro.2010.07.044

Parekkadan B, Upadhyay R, Dunham J, Iwamoto Y, Mizoguchi E, Mizoguchi A, Weissleder R, Yarmush ML

Bone Marrow Stromal Cell Transplants Prevent Experimental Enterocolitis and Require Host CD11b+ Splenocytes. Gastroenterology. 2010;140(3):966-975.e4 - PMID: 20955701 - PMCID: PMC3033974 - DOI: 10.1053/j.gastro.2010.10.013

Corradini E, Rozier M, Meynard D, Odhiambo A, Lin HY, Feng Q, Migas MC, Britton RS, Babitt JL, Fleming RE

Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe. Gastroenterology. 2011;141(5):1907-14 - PMID: 21745449 - PMCID: PMC3634343 - DOI: 10.1053/j.gastro.2011.06.077

Conway KL, Kuballa P, Song JH, Patel KK, Castoreno AB, Yilmaz OH, Jijon HB, Zhang M, Aldrich LN, Villablanca EJ, Peloquin JM, Goel G, Lee IA, Mizoguchi E, Shi HN, Bhan AK, Shaw SY, Schreiber SL, Virgin HW, Shamji AF, Stappenbeck TS, Reinecker HC, Xavier RJ

Atg16l1 is Required for Autophagy in Intestinal Epithelial Cells and Protection of Mice from Salmonella Infection. Gastroenterology. 2013;145(6):1347-57 - PMID: 23973919 - PMCID: PMC3840157 - DOI: 10.1053/j.gastro.2013.08.035

Yang KS, Ciprani D, O'Shea A, Liss A, Yang R, Fletcher-Mercaldo S, Mino-Kenudson M, Castillo CF, Weissleder R

Extracellular Vesicle Analysis Allows for Identification of Invasive IPMN Gastroenterology. 2020;160(4):1345-1358.e11 - PMID: 33301777 - PMCID: PMC7956058 - DOI: 10.1053/j.gastro.2020.11.046

Küçükköse E, Laoukili J, Gorelick AN, Degner S, Lacle M, van den Bent L, Peters NA, Verheem A, Hung WT, Frenkel NC, Wassenaar E, Lansu N, Lenos KJ, Vermeulen L, Koopman M, Roodhart JML, Kops GJPL, Borel Rinkes IHM, Hagendoorn J, Naxerova K, Kranenburg O

Lymphatic invasion of plakoglobin-dependent tumor cell clusters drives formation of polyclonal lung metastases in colon cancer. Gastroenterology. 2023;165(2):429-444.e15 - PMID: 36906044 - DOI: 10.1053/j.gastro.2023.02.047

Rudin M, Weissleder R

Molecular imaging in drug discovery and development Nat Rev Drug Discov. 2003;2:123-31 - PMID: 12563303 - DOI: 10.1038/nrd1007

Cephas AT, Hwang WL, Maitra A, Parnas O, DelGiorno KE

It is better to light a candle than to curse the darkness: single-cell transcriptomics sheds new light on pancreas biology and disease. Gut. 2023;72(6):1211-1219 - PMID: 36997301 - PMCID: PMC10988578 - DOI: 10.1136/gutjnl-2022-329313

Swirski FK, Nahrendorf M, Libby P

The ins and outs of inflammatory cells in atheromata. Cell Metab. 2012;15(2):135-6 - PMID: 22326216 - DOI: 10.1016/j.cmet.2012.01.012

Dai N, Zhao L, Wrighting D, Krämer D, Majithia A, Wang Y, Cracan V, Borges-Rivera D, Mootha VK, Nahrendorf M, Thorburn DR, Minichiello L, Altshuler D, Avruch J

IGF2BP2/IMP2-Deficient Mice Resist Obesity through Enhanced Translation of Ucp1 mRNA and Other mRNAs Encoding Mitochondrial Proteins. Cell Metab. 2015;21(4):609-21 - PMID: 25863250 - PMCID: PMC4663978 - DOI: 10.1016/j.cmet.2015.03.006

Siwicki M, Engblom C, Pittet MJ

Gal3 Links Inflammation and Insulin Resistance. Cell Metab. 2016;24(5):655-656 - PMID: 27829136 - DOI: 10.1016/j.cmet.2016.10.014

Jain IH, Zazzeron L, Goldberger O, Marutani E, Wojtkiewicz GR, Ast T, Wang H, Schleifer G, Stepanova A, Brepoels K, Schoonjans L, Carmeliet P, Galkin A, Ichinose F, Zapol WM, Mootha VK

Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation. Cell Metab. 2019;30(4):824-832.e3 - PMID: 31402314 - PMCID: PMC6903907 - DOI: 10.1016/j.cmet.2019.07.006

Guan D, Men Y, Bartlett A, Hernández MAS, Xu J, Yi X, Li HS, Kong D, Mazitschek R, Ozcan U

Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss. Cell Metab. 2024;36(4):857-876.e10 - PMID: 38569472 - DOI: 10.1016/j.cmet.2024.02.007

Haun JB, Devaraj NK, Hilderbrand SA, Lee H, Weissleder R

Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection Nat Nanotechnol. 2010;5(9):660-5 - PMID: 20676091 - PMCID: PMC2934903 - DOI: 10.1038/nnano.2010.148

Zhao W, Schafer S, Choi J, Yamanaka YJ, Lombardi ML, Bose S, Carlson AL, Phillips JA, Teo W, Droujinine IA, Cui CH, Jain RK, Lammerding J, Love JC, Lin CP, Sarkar D, Karnik R, Karp JM

Cell-surface sensors for real-time probing of cellular environments. Nat Nanotechnol. 2011;6(8):524-31 - PMID: 21765401 - PMCID: PMC3163485 - DOI: 10.1038/nnano.2011.101

Lee H, Lytton-Jean AK, Chen Y, Love KT, Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman M, Peng CG, Charisse K, Borodovsky A, Manoharan M, Donahoe JS, Truelove J, Nahrendorf M, Langer R, Anderson DG

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat Nanotechnol. 2012;7(6):389-93 - PMID: 22659608 - PMCID: PMC3898745 - DOI: 10.1038/nnano.2012.73

Chung HJ, Castro CM, Im H, Lee H*, Weissleder R*

A magneto-DNA nanoparticle system for rapid detection and phenotyping of bacteria Nat Nanotechnol. 2013;8(5):369-75 - PMID: 23644570 - PMCID: PMC3711657 - DOI: 10.1038/nnano.2013.70

Dahlman JE, Barnes C, Khan O, Thiriot A, Jhunjunwala S, Shaw TE, Xing Y, Sager HB, Sahay G, Speciner L, Bader A, Bogorad RL, Yin H, Racie T, Dong Y, Jiang S, Seedorf D, Dave A, Sandu KS, Webber MJ, Novobrantseva T, Ruda VM, Lytton-Jean AK, Levins CG, Kalish B, Mudge DK, Perez M, Abezgauz L, Dutta P, Smith L, Charisse K, Kieran MW, Fitzgerald K, Nahrendorf M, Danino D, Tuder RM, von Andrian UH, Akinc A, Panigrahy D, Schroeder A, Kotelianski V, Langer R, Anderson DG

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight. Nat Nanotechnol. 2014;9(8):648-55 - PMID: 24813696 - PMCID: PMC4207430 - DOI: 10.1038/nnano.2014.84

Im H, Huang XJ, Gu B, Choi YK

A dielectric-modulated field-effect transistor for biosensing. Nat Nanotechnol. 2007;2(7):430-4 - PMID: 18654328 - DOI: 10.1038/nnano.2007.180

Senders ML, Meerwaldt AE, van Leent MMT, Sanchez-Gaytan BL, van de Voort JC, Toner YC, Maier A, Klein ED, Sullivan NAT, Sofias AM, Groenen H, Faries C, Oosterwijk RS, van Leeuwen EM, Fay F, Chepurko E, Reiner T, Duivenvoorden R, Zangi L, Dijkhuizen RM, Hak S, Swirski FK, Nahrendorf M, Pérez-Medina C, Teunissen AJP, Fayad ZA, Calcagno C, Strijkers GJ, Mulder WJM

Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging. Nat Nanotechnol. 2020;15(5):398-405 - PMID: 32313216 - PMCID: PMC7416336 - DOI: 10.1038/s41565-020-0642-4

Li R, Ng TSC, Wang SJ, Prytyskach M, Rodell CB, Mikula H, Kohler RH, Garlin MA, Lauffenburger DA, Parangi S, Dinulescu DM, Bardeesy N, Weissleder R, Miller MA

Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS-mutant cancer Nat Nanotechnol. 2021;16(7):830-839 - PMID: 33958764 - PMCID: PMC8491539 - DOI: 10.1038/s41565-021-00897-1

Maglia G, Heron AJ, Hwang WL, Holden MA, Mikhailova E, Li Q, Cheley S, Bayley H

Droplet networks with incorporated protein diodes show collective properties. Nat Nanotechnol. 2009;4(7):437-40 - PMID: 19581896 - DOI: 10.1038/nnano.2009.121

Rodell CB, Arlauckas SP, Cuccarese MF, Garris CS, Li R, Ahmed MS, Kohler RH, Pittet MJ, Weissleder R

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy. Nat Biomed Eng. 2018;2:578-588 - PMID: 31015631 - PMCID: PMC6192054 - DOI: 10.1038/s41551-018-0236-8

Im H, Pathania D, McFarland PJ, Sohani AR, Degani I, Allen M, Coble M, Kilcoyne A, Hong S, Rohrer L, Abramson JS, Dryden-Peterson S, Fexon L, Pivovarov M, Chabner B, Lee H, Castro CM, Weissleder R

Design and clinical validation of a point-of-care device for the diagnosis of lymphoma via contrast- enhanced microholography and machine learning Nat Biomed Eng. 2018;2(9):666-674 - PMID: 30555750 - PMCID: PMC6291220 - DOI: 10.1038/s41551-018-0265-3

Lameijer M, Binderup T, van Leent MMT, Senders ML, Fay F, Malkus J, Sanchez-Gaytan BL, Teunissen AJP, Karakatsanis N, Robson P, Zhou X, Ye Y, Wojtkiewicz G, Tang J, Seijkens TTP, Kroon J, Stroes ESG, Kjaer A, Ochando J, Reiner T, Pérez-Medina C, Calcagno C, Fisher EA, Zhang B, Temel RE, Swirski FK, Nahrendorf M, Fayad ZA, Lutgens E, Mulder WJM, Duivenvoorden R

Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates. Nat Biomed Eng. 2018;2(5):279-292 - PMID: 30936448 - PMCID: PMC6447057 - DOI: 10.1038/s41551-018-0221-2

Lee H, Castro CM

Thermophoretically enriched detection. Nat Biomed Eng. 2019;3(3):163-164 - PMID: 30948812 - DOI: 10.1038/s41551-019-0364-9

Weissleder R, Pittet MJ

The expanding landscape of inflammatory cells affecting cancer therapy Nat Biomed Eng. 2020;4(5):489-498 - PMID: 32203281 - PMCID: PMC7405944 - DOI: 10.1038/s41551-020-0524-y

Krohn-Grimberghe M, Mitchell MJ, Schloss MJ, Khan OF, Courties G, Guimaraes PPG, Rohde D, Cremer S, Kowalski PS, Sun Y, Tan M, Webster J, Wang K, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Nayar R, Frodermann V, Hulsmans M, Chung A, Hoyer FF, Swirski FK, Langer R, Anderson DG, Nahrendorf M

Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche. Nat Biomed Eng. 2020;4(11):1076-1089 - PMID: 33020600 - PMCID: PMC7655681 - DOI: 10.1038/s41551-020-00623-7

Cheong J, Yu H, Lee CY, Lee JU, Choi HJ, Lee JH, Lee H, Cheon J

Fast detection of SARS-CoV-2 RNA via the integration of plasmonic thermocycling and fluorescence detection in a portable device. Nat Biomed Eng. 2020;4(12):1159-1167 - PMID: 33273713 - PMCID: PMC8202505 - DOI: 10.1038/s41551-020-00654-0

Park J, Park JS, Huang CH, Jo A, Cook K, Wang R, Lin HY, Van Deun J, Li H, Min J, Wang L, Yoon G, Carter BS, Balaj L, Choi GS, Castro CM, Weissleder R, Lee H

An integrated magneto-electrochemical device for the rapid profiling of tumour extracellular vesicles from blood plasma Nat Biomed Eng. 2021;5(7):678-689 - PMID: 34183802 - PMCID: PMC8437135 - DOI: 10.1038/s41551-021-00752-7

Andreou C, Weissleder R, Kircher MF

Multiplexed imaging in oncology Nat Biomed Eng. 2022;6(5):527-540 - PMID: 35624151 - DOI: 10.1038/s41551-022-00891-5

Senders ML, Calcagno C, Tawakol A, Nahrendorf M, Mulder WJM, Fayad ZA

PET/MR imaging of inflammation in atherosclerosis. Nat Biomed Eng. 2022;7(3):202-220 - PMID: 36522465 - DOI: 10.1038/s41551-022-00970-7

Janizek JD, Dincer AB, Celik S, Chen H, Chen W, Naxerova K, Lee SI

Uncovering expression signatures of synergistic drug responses via ensembles of explainable machine-learning models. Nat Biomed Eng. 2023;7(6):811-829 - PMID: 37127711 - PMCID: PMC11149694 - DOI: 10.1038/s41551-023-01034-0

Qiu W, Dincer AB, Janizek JD, Celik S, Pittet MJ, Naxerova K, Lee SI

Deep profiling of gene expression across 18 human cancers. Nat Biomed Eng. 2024;9(3):333-355 - PMID: 39690287 - DOI: 10.1038/s41551-024-01290-8

Kaiser Y, Garris CS, Marinari E, Kim HS, Oh J, Pedard M, Halabi EA, Choi M, Parvanian S, Kohler R, Migliorini D, Weissleder R

Targeting immunosuppressive myeloid cells via implant-mediated slow release of small molecules to prevent glioblastoma recurrence Nat Biomed Eng. 2025;:ePub - PMID: 41125869 - DOI: 10.1038/s41551-025-01533-2

Jaffer F, Weissleder R

Molecular Imaging in the Clinical Arena JAMA. 2005;293(7):855-62 - PMID: 15713776 - DOI: 10.1001/jama.293.7.855

Min JK, Leipsic J, Pencina MJ, Berman DS, Koo BK, van Mieghem C, Erglis A, Lin FY, Dunning AM, Apruzzese P, Budoff MJ, Cole JH, Jaffer FA, Leon MB, Malpeso J, Mancini GB, Park SJ, Schwartz RS, Shaw LJ, Mauri L

Diagnostic Accuracy of Fractional Flow Reserve From Anatomic CT Angiography. JAMA. 2012;308(12):1237-45 - PMID: 22922562 - PMCID: PMC4281479 - DOI: 10.1001/2012.jama.11274

Langer R, Weissleder R

Nanotechnology. JAMA. 2015;313(2):135-136 - PMID: 25585320 - DOI: 10.1001/jama.2014.16315

Xing M, Alzahrani AS, Carson KA, Viola D, Elisei R, Bendlova B, Yip L, Mian C, Vianello F, Tuttle RM, Robenshtok E, Fagin JA, Puxeddu E, Fugazzola L, Czarniecka A, Jarzab B, O'Neill CJ, Sywak MS, Lam AK, Riesco-Eizaguirre G, Santisteban P, Nakayama H, Tufano RP, Pai SI, Zeiger MA, Westra WH, Clark DP, Clifton-Bligh R, Sidransky D, Ladenson PW, Sykorova V

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer. JAMA. 2013;309(14):1493-501 - PMID: 23571588 - PMCID: PMC3791140 - DOI: 10.1001/jama.2013.3190

Weissleder R, Ntziachristos V

Shedding light onto live molecular targets Nature Med. 2003;9:123-8 - PMID: 12514725 - DOI: 10.1038/nm0103-123

Ntziachristos V, Tung CH, Bremer C, Weissleder R

Fluorescence molecular tomography resolves protease activity in vivo Nature Med. 2002;8:757-60 - PMID: 12091907 - DOI: 10.1038/nm729

Bremer C, Tung CH, Weissleder R

In vivo molecular target assessment of matrix metalloproteinase inhibition Nature Med. 2001;7:743-8 - PMID: 11385514 - DOI: 10.1038/89126

Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP

In vivo magnetic resonance imaging of transgene expression Nature Med. 2000;6:351-5 - PMID: 10700241 - DOI: 10.1038/73219

Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T

A spatially and temporally restricted mouse model of soft tissue sarcoma. Nature Med. 2007;13(8):992-997 - PMID: 17676052 - DOI: 10.1038/nm1602

Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nature Med. 2008;14(2):181-7 - PMID: 18193058 - DOI: 10.1038/nm1703

Kaushal S, Amiel G, Guleserian K, Shapira O, Perry T, Sutherland F, Rabkin E, Moran A, Schoen F, Atala A, Soker S, Bischoff J, Mayer J

Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nature Med. 2001;7:1035-40 - PMID: 11533707 - PMCID: PMC2818999 - DOI: 10.1038/nm0901-1035

Shimizu K, Sugiyama S, Aikawa M, Fukumoto Y, Rabkin E, Libby P, Mitchell R

Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy. Nature Med. 2001;7:738-41 - PMID: 11385513 - DOI: 10.1038/89121

Lee H, Sun E, Ham D, Weissleder R

Chip-NMR biosensor for detection and molecular analysis of cells. Nature Med. 2008;14(8):869-74 - PMID: 18607350 - PMCID: PMC2729055 - DOI: 10.1038/nm.1711

Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, Garcia-Echeverria C, Weissleder R, Mahmood U, Cantley LC, Wong KK

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nature Med. 2008;14(12)::1351-1356 - PMID: 19029981 - PMCID: PMC2683415 - DOI: 10.1038/nm.1890

Dagia N, Gadhoum S, Knoblauch C, Spencer J, Zamiri P, Lin CP, Sackstein R

G-CSF induces E-selectin ligand expression on human myeloid cells. Nature Med. 2006;12:1185-90 - PMID: 16980970 - DOI: 10.1038/nm1470

Fan Z, Spencer JA, Lu Y, Pitsillides CM, Singh G, Kim P, Yun SH, Toxavidis V, Strom TB, Lin CP, Koulmanda M

In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response. Nature Med. 2010;16(6):718-22 - PMID: 20495571 - PMCID: PMC2894571 - DOI: 10.1038/nm.2155

Breton S, Smith PJ, Lui B, Brown D

Acidification of the male reproductive tract by a proton pumping (H+)-ATPase. Nature Med. 1996;2(4):470-2 - PMID: 8597961 - DOI: 10.1038/nm0496-470

Panizzi P*, Nahrendorf M*, Jose-Luiz Figueiredo JL, Panizzi J, Marinelli B, Iwamoto Y, Keliher E, Maddur AA, Waterman P, Kroh HK, Leuschner F, Aikawa E, Swirski FK, Pittet MJ, Hackeng TM, Fuentes-Prior P, Schneewind O, Bock PE, Weissleder R

In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation Nature Med. 2011;17(9):1142-6 - PMID: 21857652 - PMCID: PMC3169740 - DOI: 10.1038/nm.2423

Yoo H, Kim JW, Shishkov M, Namati E, Morse T, Shubochkin R, McCarthy JR, Ntziachristos V, Bouma BE, Jaffer FA, Tearney GJ

Intra-arterial catheter for simultaneous microstructural and molecular imaging in vivo. Nature Med. 2011;17(12):1680-4 - PMID: 22057345 - PMCID: PMC3233646 - DOI: 10.1038/nm.2555

Shao H, Chung J, Balaj L, Charest A, Bigner DD, Carter BS, Hochberg FH, Breakefield XO, Weissleder R*, Lee H*

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy Nature Med. 2012;18(12):1835-1840 - PMID: 23142818 - PMCID: PMC3518564 - DOI: 10.1038/nm.2994

Robbins CS, Hilgendorf I, Weber GF, Theurl I, Iwamoto Y, Figueiredo JL, Gorbatov R, Sukhova GK, Gerhardt LM, Smyth D, Zavitz CC, Shikatani EA, Parsons M, Rooijen NV, Lin HY, Husain M, Libby P, Nahrendorf M, Weissleder R, Swirski FK

Local proliferation dominates lesional macrophage accumulation in atherosclerosis Nature Med. 2013;19(9):1166-72 - PMID: 23933982 - PMCID: PMC3769444 - DOI: 10.1038/nm.3258

Garris C, Pittet MJ

Therapeutically reeducating macrophages to treat GBM. Nature Med. 2013;19(10):1207-1208 - PMID: 24100977 - DOI: 10.1038/nm.3355

Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT

Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nature Med. 2013;19(11):1513-7 - PMID: 24162813 - PMCID: PMC3827980 - DOI: 10.1038/nm.3364

Heidt T, Sager HB, Courties G, Dutta P, Iwamoto Y, Zaltsman A, von Zur Muhlen C, Bode C, Fricchione GL, Denninger J, Lin CP, Vinegoni C, Libby P, Swirski FK, Weissleder R, Nahrendorf M

Chronic variable stress activates hematopoietic stem cells Nature Med. 2014;20(7):754-758 - PMID: 24952646 - PMCID: PMC4087061 - DOI: 10.1038/nm.3589

Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver Nature Med. 2016;22(8):945-951 - PMID: 27428900 - PMCID: PMC4957133 - DOI: 10.1038/nm.4146

King KR, Aguirre AD, Ye YX, Sun Y, Roh JD, Ng Jr RP, Kohler RH, Arlauckas SP, Iwamoto Y, Savol A, Sadreyev RI, Kelly M, Fitzgibbons TP, Fitzgerald KA, Mitchison T, Libby P, Nahrendorf M, Weissleder R

IRF3 and type I interferons fuel a fatal response to myocardial infarction Nature Med. 2017;23(12):1481-1487 - PMID: 29106401 - PMCID: PMC6477926 - DOI: 10.1038/nm.4428

Binnewies M, Roberts EW, Kersten K, Chan V, Fearon DF, Merad M, Coussens LM, Gabrilovich DI, Ostrand-Rosenberg S, Hedrick CC, Vonderheide RH, Pittet MJ, Jain RK, Zou W, Howcroft TK, Woodhouse EC, Weinberg RA, Krummel MF

Understanding the tumor immune microenvironment (TIME) for effective therapy. Nature Med. 2018;24(5):541-550 - PMID: 29686425 - PMCID: PMC5998822 - DOI: 10.1038/s41591-018-0014-x

Nahrendorf M

Myeloid cell contributions to cardiovascular health and disease Nature Med. 2018;24(6):711-720 - PMID: 29867229 - PMCID: PMC7301893 - DOI: 10.1038/s41591-018-0064-0

Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ

The human heart contains distinct macrophage subsets with divergent origins and functions. Nature Med. 2018;24(8):1234-1245 - PMID: 29892064 - PMCID: PMC6082687 - DOI: 10.1038/s41591-018-0059-x

Frodermann V, Rohde D, Courties G, Severe N, Schloss MJ, Amatullah H, McAlpine CS, Cremer S, Hoyer FF, Ji F, van Koeverden ID, Herisson F, Honold L, Masson GS, Zhang S, Grune J, Iwamoto Y, Schmidt SP, Wojtkiewicz GR, Lee IH, Gustafsson K, Pasterkamp G, de Jager SCA, Sadreyev RI, MacFadyen J, Libby P, Ridker P, Scadden DT, Naxerova K, Jeffrey KL, Swirski FK, Nahrendorf M

Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells Nature Med. 2019;25(11):1761-1771 - PMID: 31700184 - PMCID: PMC6858591 - DOI: 10.1038/s41591-019-0633-x

Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R

In vivo imaging of proteolytic activity in atherosclerosis Circulation. 2002;105:2766-71 - PMID: 12057992 - DOI: 10.1161/01.cir.0000017860.20619.23

Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R

Molecular Imaging of Factor XIIIa Activity in Thrombosis Using a Novel, Near-Infrared Fluorescent Contrast Agent That Covalently Links to Thrombi. Circulation. 2004;110(2):170-6 - PMID: 15210587 - DOI: 10.1161/01.CIR.0000134484.11052.44

Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL.

Near-Infrared Fluorescent Imaging of Matrix Metalloproteinase Activity After Myocardial Infarction Circulation. 2005;111:1800-1805 - PMID: 15809374 - PMCID: PMC3733536 - DOI: 10.1161/01.CIR.0000160936.91849.9F

Nahrendorf M, Hu K, Frantz S, Jaffer F, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlohner S, Novikov M, Dickneite G, Reed G, Jakob P, Rosenzweig A, Bauer W, Weissleder R, Ertl G.

Factor XIII Deficiency Causes Cardiac Rupture, Impairs Wound Healing, and Aggravates Cardiac Remodeling in Mice with Myocardial Infarction Circulation. 2006;113(9):1196-1202 - PMID: 16505171 - PMCID: PMC4066325 - DOI: 10.1161/CIRCULATIONAHA.105.602094

Heller EA, Liu E, Tager AM, Yuan Q, Lin AY, Ahluwalia N, Jones K, Koehn SL, Lok VM, Aikawa E, Moore KJ, Luster AD, Gerszten RE

Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells. Circulation. 2006;113(19):2301-12 - PMID: 16682613 - DOI: 10.1161/CIRCULATIONAHA.105.605121

Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P

Inflammation in Atherosclerosis. Visualizing Matrix Metalloproteinase Action in Macrophages In Vivo. Circulation. 2006;114:55-62 - PMID: 16801460 - DOI: 10.1161/CIRCULATIONAHA.106.619056

Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R

Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis. Circulation. 2006;114:1504-1511 - PMID: 17000904 - DOI: 10.1161/CIRCULATIONAHA.106.646380

Aikawa E, Nahrendorf M, Sosnovik D, Lok VM, Jaffer FA, Aikawa M, Weissleder R

Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease. Circulation. 2007;115:377-386 - PMID: 17224478 - DOI: 10.1161/CIRCULATIONAHA.106.654913

Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V

Fluorescence Tomography and Magnetic Resonance Imaging of Myocardial Macrophage Infiltration in Infarcted Myocardium In Vivo. Circulation. 2007;115:1384-1391 - PMID: 17339546 - DOI: 10.1161/CIRCULATIONAHA.106.663351

Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, Weissleder R

Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor. Circulation. 2007;115(17):2292-8 - PMID: 17420353 - DOI: 10.1161/CIRCULATIONAHA.106.660340

Sosnovik DE, Nahrendorf M, Weissleder R

Molecular magnetic resonance imaging in cardiovascular medicine. Circulation. 2007;115(15):2076-86 - PMID: 17438163 - DOI: 10.1161/CIRCULATIONAHA.106.658930

Jaffer FA, Libby P, Weissleder R

Molecular imaging of cardiovascular disease. Circulation. 2007;116(9):1052-61 - PMID: 17724271 - DOI: 10.1161/CIRCULATIONAHA.106.647164

Aikawa E, Nahrendorf M, Figueiredo JL, Swirski F, Shtatland T, Kohler RH, Jaffer F, Aikawa M, Weissleder R.

Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation. 2007;116(24):2841-50 - PMID: 18040026 - DOI: 10.1161/CIRCULATIONAHA.107.732867

Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik D, Aikawa E, Libby P, Swirski F, Weissleder R.

Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis Circulation. 2007;117:379-387 - PMID: 18158358 - PMCID: PMC2663426 - DOI: 10.1161/CIRCULATIONAHA.107.741181

Kircher M, Grimm J, Swirski FK, Libby P, Gerszten R, Allport J, Weissleder R

Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions. Circulation. 2008;117:388-395 - PMID: 18172031 - PMCID: PMC2705289 - DOI: 10.1161/CIRCULATIONAHA.107.719765

Nahrendorf M*, Sosnovik D*, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R

Activatable Magnetic Resonance Imaging Agent Reports Myeloperoxidase Activity in Healing Infarcts and Noninvasively Detects the Antiinflammatory Effects of Atorvastatin on Ischemia-Reperfusion Injury. Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051 - DOI: 10.1161/CIRCULATIONAHA.107.756510

Libby P, Nahrendorf M, Pittet MJ, Swirski FK

Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal. Circulation. 2008;117(25):3168-70 - PMID: 18574058 - DOI: 10.1161/CIRCULATIONAHA.108.783068

Aikawa E, Whittaker P, Farber M, Mendelson K, Padera R, Aikawa M, Schoen F

Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation. 2006;113:1344-52 - PMID: 16534030 - DOI: 10.1161/CIRCULATIONAHA.105.591768

Aikawa M, Sugiyama S, Hill C, Voglic S, Rabkin E, Fukumoto Y, Schoen F, Witztum J, Libby P

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma. Circulation. 2002;106:1390-6 - PMID: 12221058 - DOI: 10.1161/01.cir.0000028465.52694.9b

Deguchi J, Aikawa E, Libby P, Vachon J, Inada M, Krane S, Whittaker P, Aikawa M

Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques. Circulation. 2005;112:2708-15 - PMID: 16230484 - DOI: 10.1161/CIRCULATIONAHA.105.562041

Lindsey M, Gannon J, Aikawa M, Schoen F, Rabkin E, Lopresti-Morrow L, Crawford J, Black S, Libby P, Mitchell P, Lee R

Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction. Circulation. 2002;105:753-8 - PMID: 11839633 - DOI: 10.1161/hc0602.103674

Larose E, Yeghiazarians Y, Libby P, Yucel E, Aikawa M, Kacher D, Aikawa E, Kinlay S, Schoen F, Selwyn A, Ganz P

Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging. Circulation. 2005;112:2324-31 - PMID: 16203910 - DOI: 10.1161/CIRCULATIONAHA.105.538942

Heller E, Liu E, Tager A, Sinha S, Roberts J, Koehn S, Libby P, Aikawa E, Chen J, Huang P, Freeman M, Moore K, Luster A, Gerszten R

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation. 2005;112:578-86 - PMID: 16043658 - DOI: 10.1161/CIRCULATIONAHA.105.545616

Sutherland F, Perry T, Yu Y, Sherwood M, Rabkin E, Masuda Y, Garcia G, McLellan D, Engelmayr G, Sacks M, Schoen F, Mayer J

From stem cells to viable autologous semilunar heart valve. Circulation. 2005;111:2783-91 - PMID: 15927990 - DOI: 10.1161/CIRCULATIONAHA.104.498378

Fukumoto Y, Deguchi J, Libby P, Rabkin-Aikawa E, Sakata Y, Chin M, Hill C, Lawler P, Varo N, Schoen F, Krane S, Aikawa M

Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques. Circulation. 2004;110:1953-9 - PMID: 15451791 - DOI: 10.1161/01.CIR.0000143174.41810.10

Waller C, Hiller K, Kahler E, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer W

Serial magnetic resonance imaging of microvascular remodeling in the infarcted rat heart. Circulation. 2001;103(11):1564-9 - PMID: 11257086 - DOI: 10.1161/01.cir.103.11.1564

Rabkin E, Aikawa M, Stone J, Fukumoto Y, Libby P, Schoen F

Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation. 2001;104:2525-32 - PMID: 11714645 - DOI: 10.1161/hc4601.099489

Aikawa M, Rabkin E, Sugiyama S, Voglic S, Fukumoto Y, Furukawa Y, Shiomi M, Schoen F, Libby P

An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation. 2001;103:276-83 - PMID: 11208689 - DOI: 10.1161/01.cir.103.2.276

Fukumoto Y, Libby P, Rabkin E, Hill C, Enomoto M, Hirouchi Y, Shiomi M, Aikawa M

Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. Circulation. 2001;103:993-9 - PMID: 11181475 - DOI: 10.1161/01.cir.103.7.993

Aikawa M, Voglic S, Sugiyama S, Rabkin E, Taubman M, Fallon J, Libby P

Dietary lipid lowering reduces tissue factor expression in rabbit atheroma. Circulation. 1999;100:1215-22 - PMID: 10484543 - DOI: 10.1161/01.cir.100.11.1215

Aikawa M, Rabkin E, Okada Y, Voglic S, Clinton S, Brinckerhoff C, Sukhova G, Libby P

Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization. Circulation. 1998;97:2433-44 - PMID: 9641696 - DOI: 10.1161/01.cir.97.24.2433

Nakagawa T, Sukhova G, Rabkin E, Winters G, Schoen F, Libby P

Acute rejection accelerates graft coronary disease in transplanted rabbit hearts. Circulation. 1995;92:987-93 - PMID: 7641383 - DOI: 10.1161/01.cir.92.4.987

Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R

Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis. Circulation. 2008;118(18):1802-9 - PMID: 18852366 - PMCID: PMC2729441 - DOI: 10.1161/CIRCULATIONAHA.108.785881

Aikawa E, Aikawa M, Libby P, Figueiredo JL, Rusanescu G, Iwamoto Y, Fukuda D, Kohler RH, Shi GP, Jaffer FA, Weissleder R

Arterial and Aortic Valve Calcification Abolished by Elastolytic Cathepsin S Deficiency in Chronic Renal Disease. Circulation. 2009;119(13):1785-94 - PMID: 19307473 - PMCID: PMC2717745 - DOI: 10.1161/CIRCULATIONAHA.108.827972

Christen T*, Nahrendorf M*, Wildgruber M, Swirski FK, Aikawa E, Waterman P, Shimizu K, Weissleder R, Libby P

Molecular Imaging of Innate Immune Cell Function in Transplant Rejection. Circulation. 2009;119(14):1925-32 - PMID: 19332470 - PMCID: PMC2676889 - DOI: 10.1161/CIRCULATIONAHA.108.796888

Dal-Bianco JP, Aikawa E, Bischoff J, Guerrero JL, Handschumacher MD, Sullivan S, Johnson B, Titus JS, Iwamoto Y, Wylie-Sears J, Levine RA, Carpentier A

Active Adaptation of the Tethered Mitral Valve. Insights Into a Compensatory Mechanism for Functional Mitral Regurgitation. Circulation. 2009;120(4):334-42 - PMID: 19597052 - PMCID: PMC2752046 - DOI: 10.1161/CIRCULATIONAHA.108.846782

Ronald JA*, Chen JW*, Chen Y, Hamilton AM, Rodriguez E, Reynolds F, Hegele RA, Rogers KA, Querol M, Bogdanov A, Weissleder R, Rutt BK

Enzyme-Sensitive Magnetic Resonance Imaging Targeting Myeloperoxidase Identifies Active Inflammation in Experimental Rabbit Atherosclerotic Plaques. Circulation. 2009;120(7):592-9 - PMID: 19652086 - PMCID: PMC2736635 - DOI: 10.1161/CIRCULATIONAHA.108.813998

Nahrendorf M, Pittet MJ, Swirski FK

Monocytes: protagonists of infarct inflammation and repair after myocardial infarction. Circulation. 2010;121(22):2437-45 - PMID: 20530020 - PMCID: PMC2892474 - DOI: 10.1161/CIRCULATIONAHA.109.916346

Cheng S*, Cohen KS*, Shaw SY*, Larson MG, Hwang SJ, McCabe EL, Martin RP, Klein RJ, Hashmi B, Hoffmann U, Fox CS, Vasan RS, O'Donnell CJ, Wang TJ

Association of Colony-Forming Units With Coronary Artery and Abdominal Aortic Calcification. Circulation. 2010;122(12):1176-1182 - PMID: 20823386 - PMCID: PMC3050056 - DOI: 10.1161/CIRCULATIONAHA.109.931279

Morishige K, Kacher DF, Libby P, Josephson L, Ganz P, Weissleder R, Aikawa M

High-Resolution Magnetic Resonance Imaging Enhanced With Superparamagnetic Nanoparticles Measures Macrophage Burden in Atherosclerosis. Circulation. 2010;122(17):1707-15 - PMID: 20937980 - PMCID: PMC3003265 - DOI: 10.1161/CIRCULATIONAHA.109.891804

Sakhuja R, Suh WM, Jaffer FA, Jang IK

Residual Thrombogenic Substrate After Rupture of a Lipid-Rich Plaque: Possible Mechanism of Acute Stent Thrombosis? Circulation. 2010;122(22):2349-2350 - PMID: 21147731 - DOI: 10.1161/CIRCULATIONAHA.110.970079

Buxton DB, Antman M, Danthi N, Dilsizian V, Fayad ZA, Garcia MJ, Jaff MR, Klimas M, Libby P, Nahrendorf M, Sinusas AJ, Wickline SA, Wu JC, Bonow RO, Weissleder R

Report of the national heart, lung, and blood institute working group on the translation of cardiovascular molecular imaging. Circulation. 2011;123(19):2157-63 - PMID: 21576680 - PMCID: PMC3119488 - DOI: 10.1161/CIRCULATIONAHA.110.000943

Shaw SY, Brettman AD

Phenotyping patient-derived cells for translational studies in cardiovascular disease. Circulation. 2011;124(22):2444-55 - PMID: 22125190 - PMCID: PMC3263367 - DOI: 10.1161/CIRCULATIONAHA.111.043943

Robbins CS, Chudnovskiy A, Rauch PJ, Figueiredo JL, Iwamoto Y, Gorbatov R, Etzrodt M, Weber GF, Ueno T, van Rooijen N, Mulligan-Kehoe MJ, Libby P, Nahrendorf M, Pittet MJ, Weissleder R, Swirski FK

Extramedullary Hematopoiesis Generates Ly-6Chigh Monocytes that Infiltrate Atherosclerotic Lesions. Circulation. 2011;125(2):364-74 - PMID: 22144566 - PMCID: PMC3263762 - DOI: 10.1161/CIRCULATIONAHA.111.061986

Moon H, Park HE, Kang J, Lee H, Cheong C, Lim YT, Ihm SH, Seung KB, Jaffer FA, Narula J, Chang K, Hong KS

Noninvasive Assessment of Myocardial Inflammation by Cardiovascular Magnetic Resonance in a Rat Model of Experimental Autoimmune Myocarditis. Circulation. 2012;125(21):2603-12 - PMID: 22550157 - DOI: 10.1161/CIRCULATIONAHA.111.075283

Degousee N, Simpson J, Fazel S, Scholich K, Angoulvant D, Angioni C, Schmidt H, Korotkova M, Stefanski E, Wang XH, Lindsay TF, Ofek E, Pierre S, Butany J, Jakobsson PJ, Keating A, Li RK, Nahrendorf M, Geisslinger G, Backx PH, Rubin BB

Lack of Microsomal Prostaglandin E2 Synthase-1 in Bone Marrow Derived Myeloid Cells Impairs Left Ventricular Function and Increases Mortality after Acute Myocardial Infarction. Circulation. 2012;125(23):2904-13 - PMID: 22589381 - DOI: 10.1161/CIRCULATIONAHA.112.099754

Majmudar MD, Keliher EJ, Heidt T, Leuschner F, Truelove J, Sena BF, Gorbatov R, Iwamoto Y, Dutta P, Wojtkiewicz G, Courties G, Sebas M, Borodovsky A, Fitzgerald K, Nolte MW, Dickneite G, Chen JW, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M

Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice. Circulation. 2013;127(20):2038-2046 - PMID: 23616627 - PMCID: PMC3661714 - DOI: 10.1161/CIRCULATIONAHA.112.000116

Kumar V, Patel N, Van Houzen N, Saini N

Brugada-type electrocardiographic changes induced by Fever. Circulation. 2013;127(21):2145-6 - PMID: 23716383 - DOI: 10.1161/CIRCULATIONAHA.112.000901

Kroll MW, Lakkireddy DR, Stone JR, Luceri RM

TASER Electronic Control Devices and Cardiac Arrests: Coincidental or Causal? Circulation. 2014;129(1):93-100 - PMID: 24396012 - DOI: 10.1161/CIRCULATIONAHA.113.004401

Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK

Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity. Circulation. 2014;129(16):1677-87 - PMID: 24488984 - PMCID: PMC3997655 - DOI: 10.1161/CIRCULATIONAHA.113.006381

Hara T, Truelove J, Tawakol A, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA

FDG-PET/CT Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus. Circulation. 2014;130(13):1044-52 - PMID: 25070665 - PMCID: PMC4174982 - DOI: 10.1161/CIRCULATIONAHA.114.008902

Tawakol A, Hara T, Truelove J, Wojtkiewicz GR, Hucker WJ, MacNabb MH, Brownell AL, Jokivarsi K, Kessinger CW, Jaff MR, Henke PK, Weissleder R, Jaffer FA

Response to Letter Regarding Article, "18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Enables the Detection of Recurrent Same-Site Deep Vein Thrombosis by Illuminating Recently Formed, Neutrophil-Rich Thrombus" Circulation. 2015;131(24):e531-2 - PMID: 26078375 - DOI: 10.1161/CIRCULATIONAHA.115.014802

Sager HB, Heidt T, Hulsmans M, Dutta P, Courties G, Sebas M, Wojtkiewicz GR, Tricot B, Iwamoto Y, Sun Y, Weissleder R, Libby P, Swirski FK, Nahrendorf M

Targeting Interleukin-1β Reduces Leukocyte Production After Acute Myocardial Infarction. Circulation. 2015;132(20):1880-90 - PMID: 26358260 - PMCID: PMC4651795 - DOI: 10.1161/CIRCULATIONAHA.115.016160

Cremer S, Nahrendorf M

Myeloid Cells Remodel the Mitral Valve. Circulation. 2018;137(23):2494-2496 - PMID: 29866774 - PMCID: PMC5992497 - DOI: 10.1161/CIRCULATIONAHA.118.033622

Hoyer FF, Nahrendorf M

Uremic Toxins Activate Macrophages. Circulation. 2019;139(1):97-100 - PMID: 30592654 - PMCID: PMC6394415 - DOI: 10.1161/CIRCULATIONAHA.118.037308

RamÍrez CM, Zhang X, Bandyopadhyay C, Rotllan N, Sugiyama MG, Aryal B, Liu X, He S, Kraehling JR, Ulrich V, Lin CS, Velazquez H, Lasunción MA, Li G, Suárez Y, Tellides G, Swirski FK, Lee WL, Schwartz MA, Sessa WC, Fernández-Hernando C

Caveolin-1 Regulates Atherogenesis by Attenuating LDL Transcytosis and Vascular Inflammation Independent of Endothelial Nitric Oxide Synthase Activation. Circulation. 2019;140(3):225-239 - PMID: 31154825 - PMCID: PMC6778687 - DOI: 10.1161/CIRCULATIONAHA.118.038571

Wang Y, Sano S, Oshima K, Sano M, Watanabe Y, Katanasaka Y, Yura Y, Jung C, Anzai A, Swirski FK, Gokce N, Walsh K

Wnt5a-Mediated Neutrophil Recruitment Has an Obligatory Role in Pressure Overload-Induced Cardiac Dysfunction. Circulation. 2019;140(6):487-499 - PMID: 31170826 - PMCID: PMC6684855 - DOI: 10.1161/CIRCULATIONAHA.118.038820

Hoyer FF, Zhang X, Coppin E, Vasamsetti SB, Modugu G, Schloss MJ, Rohde D, McAlpine CS, Iwamoto Y, Libby P, Naxerova K, Swirski FK, Dutta P, Nahrendorf M

Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes. Circulation. 2020;142(3):244-258 - PMID: 32316750 - PMCID: PMC7375017 - DOI: 10.1161/CIRCULATIONAHA.120.046038

Xiao L, Salem JE, Clauss S, Hanley A, Bapat A, Hulsmans M, Iwamoto Y, Wojtkiewicz G, Cetinbas M, Schloss MJ, Tedeschi J, Lebrun-Vignes B, Lundby A, Sadreyev RI, Moslehi JJ, Nahrendorf M, Ellinor PT, Milan DJ

Ibrutinib-Mediated Atrial Fibrillation Due to Inhibition of CSK. Circulation. 2020;142(25):2443-2455 - PMID: 33092403 - PMCID: PMC9661397 - DOI: 10.1161/CIRCULATIONAHA.120.049210

Nahrendorf M

Response by Nahrendorf to Letter Regarding Article, "Bone Marrow Endothelial Cells Regulate Myelopoiesis in Diabetes Mellitus". Circulation. 2021;143(2):e7-e8 - PMID: 33428432 - PMCID: PMC7939058 - DOI: 10.1161/CIRCULATIONAHA.120.051633

Bapat A, Schloss MJ, Yamazoe M, Grune J, Hulsmans M, Milan DJ, Nahrendorf M, Ellinor PT

A Mouse Model of Atrial Fibrillation in Sepsis. Circulation. 2023;147(13):1047-1049 - PMID: 36972346 - PMCID: PMC10057612 - DOI: 10.1161/CIRCULATIONAHA.122.060317

Grune J, Bajpai G, Ocak PT, Kaufmann E, Mentkowksi K, Pabel S, Kumowski N, Pulous FE, Tran KA, Rohde D, Zhang S, Iwamoto Y, Wojtkiewicz GR, Vinegoni C, Green U, Swirski FK, Stone JR, Lennerz JK, Divangahi M, Hulsmans M, Nahrendorf M

Virus-Induced Acute Respiratory Distress Syndrome Causes Cardiomyopathy Through Eliciting Inflammatory Responses in the Heart. Circulation. 2024;150(1):49-61 - PMID: 38506045 - PMCID: PMC11216864 - DOI: 10.1161/CIRCULATIONAHA.123.066433

Grune J, Nahrendorf M

Response by Grune and Nahrendorf to Letter Regarding Article, "Virus-Induced Acute Respiratory Distress Syndrome Causes Cardiomyopathy Through Eliciting Inflammatory Responses in the Heart". Circulation. 2025;151(5):e35-e36 - PMID: 39899631 - DOI: 10.1161/CIRCULATIONAHA.124.072688

Liong M, Shao H, Haun JB, Lee H, Weissleder R

Carboxymethylated Polyvinyl Alcohol Stabilizes Doped Ferrofluids for Biological Applications. Adv Mater. 2010;22(45):5168-72 - PMID: 20859943 - PMCID: PMC2993874 - DOI: 10.1002/adma.201002219

Liong M, Tassa C, Shaw SY, Lee H, Weissleder R

Multiplexed Magnetic Labeling Amplification Using Oligonucleotide Hybridization. Adv Mater. 2011;23(36):H254-7 - PMID: 21780311 - PMCID: PMC3584698 - DOI: 10.1002/adma.201101401

Yoon TJ*, Lee H*, Shao H, Hilderbrand SA, Weissleder R

Multicore Assemblies Potentiate Magnetic Properties of Biomagnetic Nanoparticles. Adv Mater. 2011;23(41):4793-7 - PMID: 21953810 - PMCID: PMC3224986 - DOI: 10.1002/adma.201102948

Hong S, Pirovich D, Kilcoyne A, Huang CH, Lee H, Weissleder R

Supramolecular Metallo-Bioadhesive for Minimally Invasive Use Adv Mater. 2016;28(39):8675-8680 - PMID: 27515068 - PMCID: PMC5144581 - DOI: 10.1002/adma.201602606

Im H, Bantz KC, Lee SH, Johnson TW, Haynes CL, Oh SH

Self-assembled plasmonic nanoring cavity arrays for SERS and LSPR biosensing. Adv Mater. 2013;25(19):2678-85 - PMID: 23436239 - DOI: 10.1002/adma.201204283

Kilic T, Gessner I, Cho Y, Jeong N, Quintana J, Weissleder R, Lee H

Zwitterionic polymer electroplating facilitates the preparation of electrode surface for biosensing. Adv Mater. 2021;34(8):e2107892 - PMID: 34890082 - PMCID: PMC8881349 - DOI: 10.1002/adma.202107892

Ferdosi S, Stukalov A, Hasan M, Tangeysh B, Brown TR, Wang T, Elgierari EM, Zhao X, Huang Y, Alavi A, Lee-McMullen B, Chu J, Figa M, Tao W, Wang J, Goldberg M, O'Brien ES, Xia H, Stolarczyk C, Weissleder R, Farias V, Batzoglou S, Siddiqui A, Farokhzad OC, Hornburg D

Enhanced competition at the nano-bio interface enables comprehensive characterization of protein corona dynamics and deep coverage of proteomes. Adv Mater. 2022;34(44):e2206008 - PMID: 35986672 - DOI: 10.1002/adma.202206008

Lugani S*, Halabi EA*, Oh J, Kohler R, Peterson H, Breakefield XO, Chiocca EAA, Miller MA, Garris C, Weissleder R

Dual Immunostimulatory Pathway Agonism through a Synthetic Nanocarrier Triggers Robust Anti-Tumor Immunity in Murine Glioblastoma. Adv Mater. 2022;35(7):e2208782 - PMID: 36427266 - PMCID: PMC10197197 - DOI: 10.1002/adma.202208782

Carrow KP, Hamilton HL, Hopps MP, Li Y, Qiao B, Payne NC, Thompson MP, Zhang X, Magassa A, Fattah M, Agarwal S, Vincent MP, Buyanova M, Bertin PA, Mazitschek R, Olvera de la Cruz M, Johnson DA, Johnson JA, Gianneschi NC

Inhibiting the Keap1/Nrf2 Protein-Protein Interaction with Protein-Like Polymers. Adv Mater. 2024;36(21):e2311467 - PMID: 38241649 - PMCID: PMC11257647 - DOI: 10.1002/adma.202311467

Kang M, Quintana J, Hu H, Teixeira VC, Olberg S, Banla LI, Rodriguez V, Hwang WL, Schuemann J, Parangi S, Weissleder R, Miller MA

Sustained and Localized Drug Depot Release using Radiation-Activated Scintillating Nanoparticles. Adv Mater. 2024;36(23):e2312326 - PMID: 38389502 - PMCID: PMC11161319 - DOI: 10.1002/adma.202312326

De Jager PL, Srivastava G, Lunnon K, Burgess J, Schalkwyk LC, Yu L, Eaton ML, Keenan BT, Ernst J, McCabe C, Tang A, Raj T, Replogle J, Brodeur W, Gabriel S, Chai HS, Younkin C, Younkin SG, Zou F, Szyf M, Epstein CB, Schneider JA, Bernstein BE, Meissner A, Ertekin-Taner N, Chibnik LB, Kellis M, Mill J, Bennett DA

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nat Neurosci. 2014;17(9):1156-1163 - PMID: 25129075 - PMCID: PMC4292795 - DOI: 10.1038/nn.3786

Herisson F, Frodermann V, Courties G, Rohde D, Sun Y, Vandoorne K, Wojtkiewicz GR, Santos Masson G, Vinegoni C, Kim J, Kim DE, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M

Direct vascular channels connect skull bone marrow and the brain surface enabling myeloid cell migration Nat Neurosci. 2018;21(9):1209-1217 - PMID: 30150661 - PMCID: PMC6148759 - DOI: 10.1038/s41593-018-0213-2

Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, Bennett DA, De Jager PL

Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nat Neurosci. 2018;22(1):37-46 - PMID: 30559478 - PMCID: PMC6516529 - DOI: 10.1038/s41593-018-0291-1

Cruz Hernández JC, Bracko O, Kersbergen CJ, Muse V, Haft-Javaherian M, Berg M, Park L, Vinarcsik LK, Ivasyk I, Rivera DA, Kang Y, Cortes-Canteli M, Peyrounette M, Doyeux V, Smith A, Zhou J, Otte G, Beverly JD, Davenport E, Davit Y, Lin CP, Strickland S, Iadecola C, Lorthois S, Nishimura N, Schaffer CB

Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer's disease mouse models. Nat Neurosci. 2019;22(3):413-420 - PMID: 30742116 - PMCID: PMC6508667 - DOI: 10.1038/s41593-018-0329-4

Pulous FE, Cruz-Hernandez JC, Yang C, Kaya Z, Paccalet A, Wojtkiewicz G, Capen D, Brown D, Wu JW, Schloss MJ, Vinegoni C, Richter D, Yamazoe M, Hulsmans M, Momin N, Grune J, Rohde D, McAlpine CS, Panizzi P, Weissleder R, Kim DE, Swirski FK, Lin CP, Moskowitz MA, Nahrendorf M

Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis. Nat Neurosci. 2022;25(5):567-576 - PMID: 35501382 - PMCID: PMC9081225 - DOI: 10.1038/s41593-022-01060-2

Pryce KD, Serafini RA, Ramakrishnan A, Nicolais A, Giosan IM, Polizu C, Torres-Berrío A, Vuppala S, Kronman H, Ruiz A, Gaspari S, Peña CJ, Sakloth F, Mitsi V, van Duzer J, Mazitschek R, Jarpe M, Shen L, Nestler EJ, Zachariou V

Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury. Nat Neurosci. 2023;26(7):1229-1244 - PMID: 37291337 - PMCID: PMC10752505 - DOI: 10.1038/s41593-023-01350-3

Mazzitelli JA, Pulous FE, Smyth LCD, Kaya Z, Rustenhoven J, Moskowitz MA, Kipnis J, Nahrendorf M

Skull bone marrow channels as immune gateways to the central nervous system. Nat Neurosci. 2023;26(12):2052-2062 - PMID: 37996526 - PMCID: PMC10894464 - DOI: 10.1038/s41593-023-01487-1

Frodermann V, Nahrendorf M

Macrophages and Cardiovascular Health. Physiol Rev. 2018;98(4):2523-2569 - PMID: 30156496 - PMCID: PMC6442921 - DOI: 10.1152/physrev.00068.2017

Razansky D, Distel M, Vinegoni C, Ma R, Perrimon N, Koster RW, Ntziachristos V

Multispectral opto-acoustic tomography of deep-seated fluorescent proteins in vivo Nat Photonics. 2009;3:412 - 417

Mahmood U

Near infrared optical applications in molecular imaging. Earlier, more accurate assessment of disease presence, disease course, and efficacy of disease treatment. IEEE Eng Med Biol. 2004;23(4):58-66 - PMID: 15508386 - DOI: 10.1109/memb.2004.1337950

Gounari F, Chang R, Cowan J, Guo Z, Dose M, Gounaris E, Khazaie K.

Loss of adenomatous polyposis coli gene function disrupts thymic development Nat Immunol. 2005;6(8):800-9 - PMID: 16025118 - PMCID: PMC4662936 - DOI: 10.1038/ni1228

Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C

Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006;7(3):284-92 - PMID: 16444258 - DOI: 10.1038/ni1306

Fu W, Wojtkiewicz G, Weissleder R, Benoist C, Mathis D

Early window of diabetes determinism in NOD mice, dependent on the complement receptor CRIg, identified by noninvasive imaging. Nat Immunol. 2012;13(4):361-8 - PMID: 22366893 - PMCID: PMC3309063 - DOI: 10.1038/ni.2233

Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, Shikatani EA, El-Maklizi M, Williams JW, Robins L, Li C, Lewis B, Yun TJ, Lee JS, Wieghofer P, Khattar R, Farrokhi K, Byrne J, Ouzounian M, Zavitz CC, Levy GA, Bauer CM, Libby P, Husain M, Swirski FK, Cheong C, Prinz M, Hilgendorf I, Randolph GJ, Epelman S, Gramolini AO, Cybulsky MI, Rubin BB, Robbins CS

Self-renewing resident arterial macrophages arise from embryonic CX3CR1+ precursors and circulating monocytes immediately after birth Nat Immunol. 2015;17(2):159-168 - PMID: 26642357 - DOI: 10.1038/ni.3343

Garris CS, Wu L, Acharya S, Arac A, Blaho VA, Huang Y, Moon BS, Axtell RC, Ho PP, Steinberg GK, Lewis DB, Sobel RA, Han DK, Steinman L, Snyder MP, Hla T, Han MH

Defective sphingosine 1-phosphate receptor 1 (S1P1) phosphorylation exacerbates TH17-mediated autoimmune neuroinflammation. Nat Immunol. 2013;14(11):1166-72 - PMID: 24076635 - PMCID: PMC4014310 - DOI: 10.1038/ni.2730

Schloss MJ, Hulsmans M, Rohde D, Lee IH, Severe N, Foy BH, Pulous FE, Zhang S, Kokkaliaris KD, Frodermann V, Courties G, Yang C, Iwamoto Y, Knudsen AS, McAlpine CS, Yamazoe M, Schmidt SP, Wojtkiewicz GR, Masson GS, Gustafsson K, Capen D, Brown D, Higgins JM, Scadden DT, Libby P, Swirski FK, Naxerova K, Nahrendorf M

B lymphocyte-derived acetylcholine limits steady-state and emergency hematopoiesis. Nat Immunol. 2022;23(4):605-618 - PMID: 35352063 - PMCID: PMC8989652 - DOI: 10.1038/s41590-022-01165-7

Chen ACY, Jaiswal S, Martinez D, Yerinde C, Ji K, Miranda V, Fung ME, Weiss SA, Zschummel M, Taguchi K, Garris CS, Mempel TR, Hacohen N, Sen DR

The aged tumor microenvironment limits T cell control of cancer. Nat Immunol. 2024;25(6):1033-1045 - PMID: 38745085 - PMCID: PMC11500459 - DOI: 10.1038/s41590-024-01828-7

Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Cote D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood. 2007;109:2708-17 - PMID: 17119115 - PMCID: PMC1852222 - DOI: 10.1182/blood-2006-07-035857

Leleu X, Jia X, Runnels J, Ngo HT, Moreau AS, Farag M, Spencer JA, Pitsillides CM, Hatjiharissi E, Roccaro A, O'Sullivan G, McMillin DW, Moreno D, Kiziltepe T, Carrasco R, Treon SP, Hideshima T, Anderson KC, Lin CP, Ghobrial IM

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia. Blood. 2007;110:4417-26 - PMID: 17761832 - PMCID: PMC2234792 - DOI: 10.1182/blood-2007-05-092098

Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood. 2008;111(10):5195-204 - PMID: 18326817 - PMCID: PMC2384142 - DOI: 10.1182/blood-2007-09-111567

Rufer N, Zippelius A, Batard P, Pittet M, Kurth I, Corthesy P, Cerottini J, Leyvraz S, Roosnek E, Nabholz M, Romero P

Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood. 2003;102:1779-87 - PMID: 12750165 - DOI: 10.1182/blood-2003-02-0420

Kerre T, De Smet G, De Smedt M, Zippelius A, Pittet M, Langerak A, De Bosscher J, Offner F, Vandekerckhove B, Plum J

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells. Blood. 2002;99:1620-6 - PMID: 11861276 - DOI: 10.1182/blood.v99.5.1620

Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J, Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE, Anderson KC, Ghobrial IM

microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922 - DOI: 10.1182/blood-2009-01-198408

Azab AK, Azab F, Blotta S, Pitsillides CM, Thompson B, Runnels JM, Roccaro AM, Ngo HT, Melhem MR, Sacco A, Jia X, Anderson KC, Lin CP, Rollins BJ, Ghobrial IM

Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma. Blood. 2009;114(3):619-29 - PMID: 19443661 - PMCID: PMC2713475 - DOI: 10.1182/blood-2009-01-199281

Azab A, Runnels J, Pitsillides C, Moreau A, Azab F, Leleu X, Jia X, Wright R, Ospina B, Carlson A, Alt C, Burwick N, Roccaro A, Ngo H, Farag M, Melhem M, Sacco A, Munshi N, Hideshima T, Rollins B, Anderson K, Kung A, Lin CP, Ghobrial I

CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy. Blood. 2009;113:4341-51 - PMID: 19139079 - PMCID: PMC2676090 - DOI: 10.1182/blood-2008-10-186668

Kunstfeld R, Hirakawa S, Hong Y-K, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin CP, Fiebiger E, Wu Y, Hicklin D, Bohlen P, Detmar M

VEGF-A overexpression leads to lymphatic vessel enlargement and persistent skin inflammation Blood. 2004;104:1048-57

Higgins JM, Sloan SR

Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders. Blood. 2008;112(6):2546-53 - PMID: 18535200 - DOI: 10.1182/blood-2008-03-146415

Higgins JM, Sloan SR

Response: Other factors may contribute to differences between sickle cell and non-sickle cell patients. Blood. 2010;115(21):4315-6 - PMID: 20508172

Meynard D, Vaja V, Sun CC, Corradini E, Chen S, Lopez-Otin C, Grgurevic L, Hong CC, Stirnberg M, Gutschow M, Vukicevic S, Babitt JL, Lin HY

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice. Blood. 2011;118(3):747-56 - PMID: 21622652 - PMCID: PMC3142910 - DOI: 10.1182/blood-2011-04-348698

Theurl I, Schroll A, Sonnweber T, Nairz M, Theurl M, Willenbacher W, Eller K, Wolf D, Seifert M, Sun CC, Babitt JL, Hong CC, Menhall T, Gearing P, Lin HY, Weiss G

Pharmacologic inhibition of hepcidin expression reverses anemia of chronic disease in rats. Blood. 2011;118(18):4977-84 - PMID: 21730356 - PMCID: PMC3208302 - DOI: 10.1182/blood-2011-03-345066

Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA

Differential niche and Wnt requirements during acute myeloid leukemia progression. Blood. 2011;118(10):2849-56 - PMID: 21765021 - PMCID: PMC3172801 - DOI: 10.1182/blood-2011-03-345165

Sarkar D, Spencer JA, Phillips JA, Zhao W, Schafer S, Spelke DP, Mortensen LJ, Ruiz JP, Vemula PK, Sridharan R, Kumar S, Karnik R, Lin CP, Karp JM

Engineered cell homing. Blood. 2011;118(25):e184-91 - PMID: 22034631 - PMCID: PMC3242725 - DOI: 10.1182/blood-2010-10-311464

Maiso P, Liu Y, Morgan B, Azab A, Ren P, Martin MB, Zhang Y, Liu Y, Sacco A, Ngo H, Azab F, Quang P, Rodig SJ, Lin CP, Roccaro A, Rommel C, Ghobrial IM

Defining the role of TORC1 and TORC2 in multiple myeloma. Blood. 2011;118(26):6860-70 - PMID: 22045983 - PMCID: PMC3245208 - DOI: 10.1182/blood-2011-03-342394

Azab AK, Quang P, Azab F, Pitsillides C, Thompson B, Chonghaile T, Patton JT, Maiso P, Monrose V, Sacco A, Ngo HT, Flores LM, Lin CP, Magnani JL, Kung AL, Letai A, Carrasco R, Roccaro AM, Ghobrial IM

P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment. Blood. 2011;119(6):1468-78 - PMID: 22096244 - PMCID: PMC3286211 - DOI: 10.1182/blood-2011-07-368050

Santo L, Hideshima T, Kung AL, Tseng JC, Tamang D, Yang M, Jarpe M, van Duzer JH, Mazitschek R, Ogier WC, Cirstea D, Rodig S, Eda H, Scullen T, Canavese M, Bradner J, Anderson KC, Jones SS, Raje N

Preclinical activity, pharmacodynamic and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma. Blood. 2012;119(11):2579-89 - PMID: 22262760 - PMCID: PMC3337713 - DOI: 10.1182/blood-2011-10-387365

Mosley AJ, Meekings KN, McCarthy C, Shepherd D, Cerundolo V, Mazitschek R, Tanaka Y, Taylor GP, Bangham CR

Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection. Blood. 2006;108(12):3801-7 - PMID: 16912225 - DOI: 10.1182/blood-2006-03-013235

Azab AK, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, Thompson B, Maiso P, Sun JD, Hart CP, Roccaro AM, Sacco A, Ngo HT, Lin CP, Kung AL, Carrasco RD, Vanderkerken K, Ghobrial IM

Hypoxia promotes dissemination of multiple myeloma through acquisition of endothelial to mesenchymal transition-like features. Blood. 2012;119(24):5782-94 - PMID: 22394600 - PMCID: PMC3382938 - DOI: 10.1182/blood-2011-09-380410

Cohen KS, Cheng S, Larson MG, Cupples LA, McCabe EL, Wang YA, Ngwa JS, Martin RP, Klein RJ, Hashmi B, Ge Y, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ

Circulating CD34+ progenitor cell frequency is associated with clinical and genetic factors. Blood. 2013;121(8):e50-6 - PMID: 23287867 - PMCID: PMC3578962 - DOI: 10.1182/blood-2012-05-424846

Levy O, Zhao W, Mortensen LJ, Leblanc S, Tsang K, Fu M, Phillips JA, Sagar V, Anandakumaran P, Ngai J, Cui CH, Eimon P, Angel M, Lin CP, Yanik MF, Karp JM

mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation. Blood. 2013;122(14):e23-e32 - PMID: 23980067 - PMCID: PMC3790516 - DOI: 10.1182/blood-2013-04-495119

Meynard D, Babitt JL, Lin HY

The liver: conductor of systemic iron regulation. Blood. 2013;123(2):168-76 - PMID: 24200681 - PMCID: PMC3888285 - DOI: 10.1182/blood-2013-06-427757

Babitt JL, Lin HY

BuMPing iron with modified heparins. Blood. 2014;123(10):1440-1 - PMID: 24627550 - PMCID: PMC3945857 - DOI: 10.1182/blood-2014-01-549519

Nicolaou F, Teodoridis JM, Park H, Georgakis A, Farokhzad OC, Böttinger EP, Da Silva N, Rousselot P, Chomienne C, Ferenczi K, Arnaout MA, Shelley CS

CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD. Blood. 2003;101(10):4033-41 - PMID: 12576324 - DOI: 10.1182/blood-2002-01-0324

Da Silva N, Bharti A, Shelley CS

hnRNP-K and Pur(alpha) act together to repress the transcriptional activity of the CD43 gene promoter. Blood. 2002;100(10):3536-44 - PMID: 12411317 - DOI: 10.1182/blood.V100.10.3536

Saez B, Ferraro F, Yusuf RZ, Cook CM, Yu VW, Pardo-Saganta A, Sykes SM, Palchaudhuri R, Schajnovitz A, Lotinun S, Lymperi S, Mendez-Ferrer S, Del Toro R, Day R, Vasic R, Acharya SS, Baron R, Lin CP, Yamaguchi Y, Wagers AJ, Scadden DT

Inhibiting stromal cell heparan sulfate synthesis improves stem cell mobilization and enables engraftment without cytotoxic conditioning. Blood. 2014;124(19):2937-47 - PMID: 25202142 - PMCID: PMC4224192 - DOI: 10.1182/blood-2014-08-593426

Renneville A, Van Galen P, Canver MC, McConkey M, Krill-Burger JM, Dorfman DM, Holson EB, Bernstein BE, Orkin SH, Bauer DE, Ebert BL

EHMT1 and EHMT2 inhibition induce fetal hemoglobin expression. Blood. 2015;126(16):1930-9 - PMID: 26320100 - PMCID: PMC4608240 - DOI: 10.1182/blood-2015-06-649087

Nai A, Rubio A, Campanella A, Gourbeyre O, Artuso I, Bordini J, Gineste A, Latour C, Besson-Fournier C, Lin HY, Coppin H, Roth MP, Camaschella C, Silvestri L, Meynard D

Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice. Blood. 2016;127(19):2327-36 - PMID: 26755707 - PMCID: PMC4865590 - DOI: 10.1182/blood-2015-11-681494

Canali S, Zumbrennen-Bullough KB, Core AB, Wang CY, Nairz M, Bouley R, Swirski FK, Babitt JL

Endothelial cells produce bone morphogenetic protein 6 required for iron homeostasis in mice. Blood. 2016;129(4):405-414 - PMID: 27864295 - PMCID: PMC5270389 - DOI: 10.1182/blood-2016-06-721571

Wang CY, Core AB, Canali S, Zumbrennen-Bullough KB, Ozer S, Umans L, Zwijsen A, Babitt JL

Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice. Blood. 2017;130(1):73-83 - PMID: 28438754 - PMCID: PMC5501149 - DOI: 10.1182/blood-2016-12-759423

Wang CY, Babitt JL

Liver iron sensing and body iron homeostasis. Blood. 2018;133(1):18-29 - PMID: 30401708 - PMCID: PMC6318427 - DOI: 10.1182/blood-2018-06-815894

Wang CY, Xu Y, Traeger L, Dogan DY, Xiao X, Steinbicker AU, Babitt JL

Erythroferrone lowers hepcidin by sequestering BMP2/6 heterodimer from binding to the BMP type I receptor ALK3. Blood. 2020;135(6):453-456 - PMID: 31800957 - PMCID: PMC7005366 - DOI: 10.1182/blood.2019002620

Park SY, Matte A, Jung Y, Ryu J, Wilson AB, Han EYA, Liu M, Carbone C, Melisi D, Nagasawa T, Locascio JJ, Lin CP, Silberstein LE, De Franceschi L

Pathologic angiogenesis in the bone marrow of humanized sickle cell mice is reversible by blood transfusion. Blood. 2020;135(23):2071-2084 - PMID: 31990287 - PMCID: PMC7273832 - DOI: 10.1182/blood.2019002227

Al-Samkari H, Karp Leaf RS, Dzik WH, Carlson JC, Fogerty AE, Waheed A, Goodarzi K, Bendapudi P, Bornikova L, Gupta S, Leaf D, Kuter DJ, Rosovsky RP

COVID and Coagulation: Bleeding and Thrombotic Manifestations of SARS-CoV2 Infection. Blood. 2020;136(4):489-500 - PMID: 32492712 - PMCID: PMC7378457 - DOI: 10.1182/blood.2020006520

Man CH, Mercier FE, Liu N, Dong W, Stephanopoulos G, Jiang L, Jung Y, Lin CP, Leung AYH, Scadden DT

Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth. Blood. 2022;139(4):502-522 - PMID: 34610101 - PMCID: PMC8796654 - DOI: 10.1182/blood.2021011563

Miller P, Fell G, Foy B, Scherer A, Gibson CJ, Sperling AS, Burugula BB, Nakao T, Uddin MM, Warren H, Bry L, Pozdnyakova O, Frigault MJ, Bick AG, Neuberg D, Higgins JM, Mansour M, Natarajan P, Kim AS, Kitzman J, Ebert BL

Clonal Hematopoiesis of Indeterminate Potential and Risk of Death from COVID-19. Blood. 2022;140(18):1993-1997 - PMID: 36096050 - PMCID: PMC9474399 - DOI: 10.1182/blood.2022018052

Rhee C, Scadden EW, Wong LP, Schiroli G, Mazzola MC, Chea PL, Kato H, Hoyer FF, Mistry M, Lee BK, Kim J, Nahrendorf M, Mansour M, Sykes DB, Sadreyev R, Scadden DT

Limited plasticity of monocyte fate and function associated with epigenetic scripting at the level of progenitors. Blood. 2023;142(7):658-674 - PMID: 37267513 - PMCID: PMC10447620 - DOI: 10.1182/blood.2023020257

Aiden AP, Rivera MN, Rheinbay E, Ku M, Coffman EJ, Truong TT, Vargas SO, Lander ES, Haber DA, Bernstein BE

Wilms Tumor Chromatin Profiles Highlight Stem Cell Properties and a Renal Developmental Network. Cell Stem Cell. 2010;6(6):591-602 - PMID: 20569696 - PMCID: PMC2897075 - DOI: 10.1016/j.stem.2010.03.016

Koche RP, Smith ZD, Adli M, Gu H, Ku M, Gnirke A, Bernstein BE, Meissner A

Reprogramming factor expression initiates widespread targeted chromatin remodeling. Cell Stem Cell. 2011;8(1):96-105 - PMID: 21211784 - PMCID: PMC3220622 - DOI: 10.1016/j.stem.2010.12.001

Park D, Spencer JA, Koh BI, Kobayashi T, Fujisaki J, Clemens TL, Lin CP, Kronenberg HM, Scadden DT

Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration. Cell Stem Cell. 2012;10(3):259-72 - PMID: 22385654 - PMCID: PMC3652251 - DOI: 10.1016/j.stem.2012.02.003

Silberstein LE, Lin CP

A new image of the hematopoietic stem cell vascular niche. Cell Stem Cell. 2013;13(5):514-6 - PMID: 24209758 - PMCID: PMC4148778 - DOI: 10.1016/j.stem.2013.10.012

Dutta P, Sager HB, Stengel KR, Naxerova K, Courties G, Saez B, Silberstein L, Heidt T, Sebas M, Sun Y, Wojtkiewicz G, Feruglio PF, King K, Baker JN, van der Laan AM, Borodovsky A, Fitzgerald K, Hulsmans M, Hoyer F, Iwamoto Y, Vinegoni C, Brown D, Di Carli M, Libby P, Hiebert SW, Scadden DT, Swirski FK, Weissleder R, Nahrendorf M

Myocardial Infarction Activates CCR2(+) Hematopoietic Stem and Progenitor Cells Cell Stem Cell. 2015;16 (5):477-487 - PMID: 25957903 - PMCID: PMC4426344 - DOI: 10.1016/j.stem.2015.04.008

Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT

Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators. Cell Stem Cell. 2016;19(4):530-543 - PMID: 27524439 - PMCID: PMC5402355 - DOI: 10.1016/j.stem.2016.07.004

Liau BB, Sievers C, Donohue LK, Gillespie SM, Flavahan WA, Miller TE, Venteicher AS, Hebert CH, Carey CD, Rodig SJ, Shareef SJ, Najm FJ, van Galen P, Wakimoto H, Cahill DP, Rich JN, Aster JC, Suvà ML, Patel AP, Bernstein BE

Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Cell Stem Cell. 2016;20(2):233-246.e7 - PMID: 27989769 - PMCID: PMC5291795 - DOI: 10.1016/j.stem.2016.11.003

Scaramozza A, Park D, Kollu S, Beerman I, Sun X, Rossi DJ, Lin CP, Scadden DT, Crist C, Brack AS

Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress. Cell Stem Cell. 2019;24(6):944-957.e5 - PMID: 31006621 - PMCID: PMC6597014 - DOI: 10.1016/j.stem.2019.03.020

Severe N, Karabacak NM, Gustafsson K, Baryawno N, Courties G, Kfoury Y, Kokkaliaris KD, Rhee C, Lee D, Scadden EW, Garcia-Robledo JE, Brouse T, Nahrendorf M, Toner M, Scadden DT

Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping. Cell Stem Cell. 2019;25(4):570-583.e7 - PMID: 31279774 - PMCID: PMC6778015 - DOI: 10.1016/j.stem.2019.06.003

Bonora M, Morganti C, van Gastel N, Ito K, Calura E, Zanolla I, Ferroni L, Zhang Y, Jung Y, Sales G, Martini P, Nakamura T, Lasorsa FM, Finkel T, Lin CP, Zavan B, Pinton P, Georgakoudi I, Romualdi C, Scadden DT, Ito K

A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate. Cell Stem Cell. 2024;31(3):359-377.e10 - PMID: 38458178 - PMCID: PMC10957094 - DOI: 10.1016/j.stem.2024.02.004

Ferraro GB, Ali A, Luengo A, Kodack DP, Deik A, Abbott KL, Bezwada D, Blanc L, Prideaux B, Jin X, Possada JM, Chen J, Chin CR, Amoozgar Z, Ferreira R, Chen I, Naxerova K, Ng C, Westermark AM, Duquette M, Roberge S, Lindeman NI, Lyssiotis CA, Nielsen J, Housman DE, Duda DG, Brachtel E, Golub TR, Cantley LC, Asara JM, Davidson SM, Fukumura D, Dartois VA, Clish CB, Jain RK, Vander Heiden MG

Fatty acid synthesis is required for breast cancer brain metastasis. Nat Cancer. 2021;2(4):414-428 - PMID: 34179825 - PMCID: PMC8223728 - DOI: 10.1038/s43018-021-00183-y

Burr R, Leshchiner I, Costantino CL, Blohmer M, Sundaresan T, Cha J, Seeger K, Guay S, Danysh BP, Gore I, Jacobs RA, Slowik K, Utro F, Rhrissorrakrai K, Levovitz C, Barth JL, Dubash T, Chirn B, Parida L, Sequist LV, Lennerz JK, Mino-Kenudson M, Maheswaran S, Naxerova K, Getz G, Haber DA

Developmental mosaicism underlying EGFR-mutant lung cancer presenting with multiple primary tumors. Nat Cancer. 2024;5(11):1681-1696 - PMID: 39406916 - PMCID: PMC11584400 - DOI: 10.1038/s43018-024-00840-y

Liu JF, Herold C, Gray KP, Penson RT, Horowitz N, Konstantinopoulos PA, Castro CM, Hill SJ, Curtis J, Luo W, Matulonis UA, Cannistra SA, Dizon DS

Assessment of Combined Nivolumab and Bevacizumab in Relapsed Ovarian Cancer: A Phase 2 Clinical Trial. JAMA Oncol. 2019;5(12):1731-1738 - PMID: 31600397 - PMCID: PMC6802049 - DOI: 10.1001/jamaoncol.2019.3343

Hwang WL, Niemierko A, Efstathiou JA

Comparing Adjuvant vs Early-Salvage Radiotherapy After Radical Prostatectomy-Reply. JAMA Oncol. 2018;4(11):1620-1621 - PMID: 30422248 - DOI: 10.1001/jamaoncol.2018.3552

Hwang WL, Tendulkar RD, Niemierko A, Agrawal S, Stephans KL, Spratt DE, Hearn JW, Koontz BF, Lee WR, Michalski JM, Pisansky TM, Liauw SL, Abramowitz MC, Pollack A, Moghanaki D, Anscher MS, Den RB, Zietman AL, Stephenson AJ, Efstathiou JA

Comparison Between Adjuvant and Early-Salvage Postprostatectomy Radiotherapy for Prostate Cancer With Adverse Pathological Features. JAMA Oncol. 2018;4(5):e175230 - PMID: 29372236 - PMCID: PMC5885162 - DOI: 10.1001/jamaoncol.2017.5230

Hwang WL, Niemierko A, Hwang KL, Hubbeling H, Schapira E, Gainor JF, Keane FK

Clinical Outcomes in Patients With Metastatic Lung Cancer Treated With PD-1/PD-L1 Inhibitors and Thoracic Radiotherapy. JAMA Oncol. 2018;4(2):253-255 - PMID: 28973343 - PMCID: PMC5838581 - DOI: 10.1001/jamaoncol.2017.3808

Lee CY, Degani I, Cheong J, Weissleder R, Lee JH, Cheon J, Lee H

Development of Integrated Systems for On-Site Infection Detection. Acc Chem Res. 2021;54(21):3991-4000 - PMID: 34677927 - PMCID: PMC9099220 - DOI: 10.1021/acs.accounts.1c00498

Cheon J, Qin J, Lee LP, Lee H

Advances in Biosensor Technologies for Infection Diagnostics. Acc Chem Res. 2022;55(2):121-122 - PMID: 35038867 - DOI: 10.1021/acs.accounts.1c00647

Villalba JA, Hilburn CF, Garlin MA, Elliott GA, Li Y, Kunitoki K, Poli S, Alba GA, Madrigal E, Taso M, Price MC, Aviles AJ, Araujo-Medina M, Bonanno L, Boyraz B, Champion SN, Harris CK, Helland TL, Hutchison B, Jobbagy S, Marshall MS, Shepherd DJ, Barth JL, Hung YP, Ly A, Hariri LP, Turbett SE, Pierce VM, Branda JA, Rosenberg ES, Mendez-Pena J, Chebib I, Rosales IA, Smith RN, Miller MA, Rosas IO, Hardin CC, Baden LR, Medoff BD, Colvin RB, Little BP, Stone JR, Mino-Kenudson M, Shih AR

Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and ARDS. Am J Respir Crit Care Med. 2022;206(7):857-873 - PMID: 35671465 - PMCID: PMC9799276 - DOI: 10.1164/rccm.202109-2150OC

Devaraj NK, Weissleder R

Biomedical Applications of Tetrazine Cycloadditions. Accounts Chem Res. 2011;44(9):816-27 - PMID: 21627112 - PMCID: PMC3166440 - DOI: 10.1021/ar200037t

Tassa C, Shaw SY, Weissleder R

Dextran-Coated Iron Oxide Nanoparticles: A Versatile Platform for Targeted Molecular Imaging, Molecular Diagnostics, and Therapy. Accounts Chem Res. 2011;44(10):842-52 - PMID: 21661727 - PMCID: PMC3182289 - DOI: 10.1021/ar200084x

Hurtado-Lorenzo A, Skinner M, El Annan J, Futai M, Sun-Wada GH, Bourgoin S, Casanova J, Wildeman A, Bechoua S, Ausiello DA, Brown D, Marshansky V

V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat Cell Biol. 2006;8(2):124-36 - PMID: 16415858 - DOI: 10.1038/ncb1348

Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA

Programming human pluripotent stem cells into white and brown adipocytes. Nat Cell Biol. 2012;14(2):209-19 - PMID: 22246346 - PMCID: PMC3385947 - DOI: 10.1038/ncb2411

Brumbaugh J, Kim IS, Ji F, Huebner AJ, Di Stefano B, Schwarz BA, Charlton J, Coffey A, Choi J, Walsh RM, Schindler JW, Anselmo A, Meissner A, Sadreyev RI, Bernstein BE, Hock H, Hochedlinger K

Inducible histone K-to-M mutations are dynamic tools to probe the physiological role of site-specific histone methylation in vitro and in vivo. Nat Cell Biol. 2019;21(11):1449-1461 - PMID: 31659274 - PMCID: PMC6858577 - DOI: 10.1038/s41556-019-0403-5

Barth I, Lee H

Phase-driven progress in nanophotonic biosensing. Light Sci Appl. 2024;13(1):76 - PMID: 38494520 - PMCID: PMC10944832 - DOI: 10.1038/s41377-024-01415-3

Barth I, Lee H

Nanophotonic sensing and label-free imaging of extracellular vesicles. Light Sci Appl. 2025;14(1):177 - PMID: 40295495 - PMCID: PMC12037801 - DOI: 10.1038/s41377-025-01866-2

Lim PJ, Duarte TL, Arezes J, Garcia-Santos D, Hamdi A, Pasricha SR, Armitage AE, Mehta H, Wideman S, Santos AG, Santos-Gonçalves A, Morovat A, Hughes JR, Soilleux E, Wang CY, Bayer AL, Klenerman P, Willberg CB, Hartley RC, Murphy MP, Babitt JL, Ponka P, Porto G, Drakesmith H

Nrf2 controls iron homeostasis in haemochromatosis and thalassaemia via Bmp6 and hepcidin. Nat Metab. 2019;1(5):519-531 - PMID: 31276102 - PMCID: PMC6609153 - DOI: 10.1038/s42255-019-0063-6

Kakkar A, Traverso G, Farokhzad OC, Weissleder R, Langer R

Evolution of macromolecular complexity in drug delivery systems. Nat Rev Chem. 2017;1(8):ePub - PMID: 31286060 - PMCID: PMC6613785 - DOI: 10.1038/s41570-017-0063

Jaffer F, Libby P, Weissleder R.

Molecular and Cellular Imaging of Atherosclerosis, Emerging Applications J Am Coll Cardiol. 2006;47:1328-1338 - PMID: 16580517 - DOI: 10.1016/j.jacc.2006.01.029

Nahrendorf M, Hu K, Hiller K, Galuppo P, Fraccarollo D, Schweizer G, Haase A, Ertl G, Bauer W, Bauersachs J

Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study. J Am Coll Cardiol. 2002;40(9):1695-700 - PMID: 12427425 - DOI: 10.1016/s0735-1097(02)02375-6

Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schar M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M

Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using positive contrast magnetic resonance imaging. J Am Coll Cardiol. 2008;52:483-91 - PMID: 18672170 - PMCID: PMC2628468 - DOI: 10.1016/j.jacc.2008.03.063

Jaffer FA

Assessing niacin as an atherosclerosis therapeutic agent valuable insights provided by high-resolution vascular magnetic resonance imaging. J Am Coll Cardiol. 2009;54(19):1795-6 - PMID: 19874993 - DOI: 10.1016/j.jacc.2009.07.026

Panizzi P, Swirski FK, Figueiredo JL, Waterman P, Sosnovik DE, Aikawa E, Libby P, Pittet M, Weissleder R, Nahrendorf M

Impaired infarct healing in atherosclerotic mice with Ly-6C(hi) monocytosis. J Am Coll Cardiol. 2010;55(15):1629-38 - PMID: 20378083 - PMCID: PMC2852892 - DOI: 10.1016/j.jacc.2009.08.089

Jaffer FA, Calfon MA, Rosenthal A, Mallas G, Razansky RN, Mauskapf A, Weissleder R, Libby P, Ntziachristos V

Two-dimensional intravascular near-infrared fluorescence molecular imaging of inflammation in atherosclerosis and stent-induced vascular injury. J Am Coll Cardiol. 2011;57(25):2516-26 - PMID: 21679853 - PMCID: PMC3123768 - DOI: 10.1016/j.jacc.2011.02.036

Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, Dutta P, Iwamoto Y, Ueno T, Begieneman MPV, Niessen HWM, Piek JJ, Vinegoni C, Pittet MJ, Swirski FK, Tawakol A, Di Carli M, Weissleder R, Nahrendorf M

PET/MRI of Inflammation in Myocardial Infarction J Am Coll Cardiol. 2012;59:153-163 - PMID: 22222080 - PMCID: PMC3257823 - DOI: 10.1016/j.jacc.2011.08.066

Swirski FK, Nahrendorf M

Macrophage - stem cell crosstalk after myocardial infarction. J Am Coll Cardiol. 2013;62(20):1902-4 - PMID: 23973700 - DOI: 10.1016/j.jacc.2013.07.058

Courties G, Heidt T, Sebas M, Iwamoto Y, Jeon D, Truelove J, Tricot B, Wojtkiewicz G, Dutta P, Sager HB, Borodovsky A, Novobrantseva T, Klebanov B, Fitzgerald K, Anderson DG, Libby P, Swirski FK, Weissleder R, Nahrendorf M

In vivo silencing of the transcription factor IRF5 reprograms the macrophage phenotype and improves infarct healing. J Am Coll Cardiol. 2013;63(15):1556-66 - PMID: 24361318 - PMCID: PMC3992176 - DOI: 10.1016/j.jacc.2013.11.023

Taqueti VR, Nahrendorf M, Di Carli MF

Translational molecular imaging: repurposing an old technique to track cell migration into human atheroma. J Am Coll Cardiol. 2014;64(10):1030-2 - PMID: 25190239 - DOI: 10.1016/j.jacc.2014.07.004

Nahrendorf M, Frantz S, Swirski FK, Mulder WJ, Randolph G, Ertl G, Ntziachristos V, Piek JJ, Stroes ES, Schwaiger M, Mann DL, Fayad ZA

Imaging Systemic Inflammatory Networks in Ischemic Heart Disease. J Am Coll Cardiol. 2015;65(15):1583-1591 - PMID: 25881940 - PMCID: PMC4401833 - DOI: 10.1016/j.jacc.2015.02.034

Libby P, Nahrendorf M, Swirski FK

Leukocytes Link Local and Systemic Inflammation in Ischemic Cardiovascular Disease: An Expanded "Cardiovascular Continuum" J Am Coll Cardiol. 2016;67(9):1091-103 - PMID: 26940931 - PMCID: PMC4779182 - DOI: 10.1016/j.jacc.2015.12.048

Xing L, Higuma T, Wang Z, Aguirre AD, Mizuno K, Takano M, Dauerman HL, Park SJ, Jang Y, Kim CJ, Kim SJ, Choi SY, Itoh T, Uemura S, Lowe H, Walters DL, Barlis P, Lee S, Lerman A, Toma C, Tan JWC, Yamamoto E, Bryniarski K, Dai J, Zanchin T, Zhang S, Yu B, Lee H, Fujimoto J, Fuster V, Jang IK

Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography: A 4-Year Follow-Up Study. J Am Coll Cardiol. 2017;69(20):2502-2513 - PMID: 28521888 - DOI: 10.1016/j.jacc.2017.03.556

Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN

Unraveling Vascular Inflammation: From Immunology to Imaging. J Am Coll Cardiol. 2017;70(11):1403-1412 - PMID: 28882238 - PMCID: PMC5658004 - DOI: 10.1016/j.jacc.2017.07.750

Swirski FK, Nahrendorf M

Clonal Hematopoiesis Wages War on the Myocardium. J Am Coll Cardiol. 2018;71(8):887-889 - PMID: 29471940 - DOI: 10.1016/j.jacc.2017.12.038

Fayad ZA, Swirski FK, Calcagno C, Robbins CS, Mulder W, Kovacic JC

Monocyte and Macrophage Dynamics in the Cardiovascular System: JACC Macrophage in CVD Series (Part 3). J Am Coll Cardiol. 2018;72(18):2198-2212 - PMID: 30360828 - PMCID: PMC6258199 - DOI: 10.1016/j.jacc.2018.08.2150

Hsue PY, Li D, Ma Y, Ishai A, Manion M, Nahrendorf M, Ganz P, Ridker PM, Deeks SG, Tawakol A

IL-1β Inhibition Reduces Atherosclerotic Inflammation in HIV Infection. J Am Coll Cardiol. 2018;72(22):2809-2811 - PMID: 30497570 - PMCID: PMC8723182 - DOI: 10.1016/j.jacc.2018.09.038

Libby P, Nahrendorf M, Swirski FK

Reply: The Networks Between the Sympathetic Nervous System and Immune System in Atherosclerosis. J Am Coll Cardiol. 2016;68(4):432 - PMID: 27443446 - DOI: 10.1016/j.jacc.2016.05.017

Ferraro B, Leoni G, Hinkel R, Ormanns S, Paulin N, Ortega-Gomez A, Viola JR, de Jong R, Bongiovanni D, Bozoglu T, Maas SL, D'Amico M, Kessler T, Zeller T, Hristov M, Reutelingsperger C, Sager HB, Döring Y, Nahrendorf M, Kupatt C, Soehnlein O

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair. J Am Coll Cardiol. 2019;73(23):2990-3002 - PMID: 31196457 - DOI: 10.1016/j.jacc.2019.03.503

Tawakol A, Osborne MT, Wang Y, Hammed B, Tung B, Patrich T, Oberfeld B, Ishai A, Shin LM, Nahrendorf M, Warner ET, Wasfy J, Fayad ZA, Koenen K, Ridker PM, Pitman RK, Armstrong KA

Stress-Associated Neurobiological Pathway Linking Socioeconomic Disparities to Cardiovascular Disease. J Am Coll Cardiol. 2019;73(25):3243-3255 - PMID: 31248544 - PMCID: PMC6767929 - DOI: 10.1016/j.jacc.2019.04.042

Libby P, Swirski FK, Nahrendorf M

The Myocardium: More Than Myocytes. J Am Coll Cardiol. 2019;74(25):3136-3138 - PMID: 31856970 - DOI: 10.1016/j.jacc.2019.10.031

Cremer S, Schloss MJ, Vinegoni C, Foy BH, Zhang S, Rohde D, Hulsmans M, Fumene Feruglio P, Schmidt S, Wojtkiewicz G, Higgins JM, Weissleder R, Swirski FK, Nahrendorf M

Diminished Reactive Hematopoiesis and Cardiac Inflammation in a Mouse Model of Recurrent Myocardial Infarction. J Am Coll Cardiol. 2020;75(8):901-915 - PMID: 32130926 - PMCID: PMC7254576 - DOI: 10.1016/j.jacc.2019.12.056

Nahrendorf M

Innate Lymphoid Cells Participate in Myocardial Inflammation After Ischemia. J Am Coll Cardiol. 2021;78(11):1143-1144 - PMID: 34503683 - DOI: 10.1016/j.jacc.2021.07.013

Aguirre AD, Arbab-Zadeh A, Soeda T, Fuster V, Jang IK

Optical Coherence Tomography of Plaque Vulnerability and Rupture: JACC Focus Seminar Part 1/3. J Am Coll Cardiol. 2021;78(12):1257-1265 - PMID: 34531027 - PMCID: PMC9851427 - DOI: 10.1016/j.jacc.2021.06.050

Atri M, Zhang Z, Marques H, Gorelick J, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Gold M,

Utility of preoperative ferumoxtran-10 enhanced MRI to evaluate retroperitoneal lymph node metastasis in advanced cervical cancer: Results of ACRIN 6671/GOG 0233. J Clin Oncol. 2011;29(15_suppl):5035 - PMID: 28023716

Gold M, Zhang Z, Marques H, Gorelick J, Landrum LM, Mannel RS, Chuang LT, Yu JQ, McCourt CK, Harisinghani M, Sohaib A, Koh D, Raman S, Gee MS, Choi H, Atri M

MRI prior to systematic lymphadenectomy in patients with locally advanced cervical cancer. J Clin Oncol. 2011;29(15_suppl):5042 - PMID: 28023697

Santo L, Hideshima T, Kung AL, Yang M, Tamang D, Jarpe M, van Duzer JH, Mazitschek R, Cirstea D, Patel K, Tseng J, Rodig S, Pozzi S, Bradner J, Anderson KC, Jones SS, Raje NS

The effect of selective inhibition of HDAC6 with ACY1215 on bortezomib activity in multiple myeloma (MM). J Clin Oncol. 2011;29(15_suppl):e18569 - PMID: 28023028

D'Souza G, Gross ND, Pai SI, Haddad R, Anderson KS, Rajan S, Gerber J, Gillison ML, Posner MR

Oral human papillomavirus (HPV) infection in HPV-positive patients with oropharyngeal cancer and their partners. J Clin Oncol. 2014;32(23):2408-15 - PMID: 24778397 - PMCID: PMC4263818 - DOI: 10.1200/JCO.2014.55.1341

Chapman S, Dobrovolskaia M, Farahani K, Goodwin A, Joshi A, Lee H, Meade T, Pomper M, Ptak K, Rao J, Singh R, Sridhar S, Stern S, Wang A, Weaver JB, Woloschak G, Yang L

Nanoparticles for cancer imaging: The good, the bad, and the promise. Nano Today. 2013;8(5):454-460 - PMID: 25419228 - PMCID: PMC4240321 - DOI: 10.1016/j.nantod.2013.06.001

Haun JB*, Castro CM*, Wang R, Peterson VM, Marinelli BS, Lee H, Weissleder R.

Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples Sci Transl Med. 2011;3(71):71ra16 - PMID: 21346169 - PMCID: PMC3086073 - DOI: 10.1126/scitranslmed.3002048

Vinegoni C, Botnaru I, Aikawa E, Calfon MA, Iwamoto Y, Folco EJ, Ntziachristos V, Weissleder R, Libby P, Jaffer FA

Indocyanine Green Enables Near-Infrared Fluorescence Imaging of Lipid-Rich, Inflamed Atherosclerotic Plaques Sci Transl Med. 2011;3 (84) ra45):84ra45 - PMID: 21613624 - PMCID: PMC3112179 - DOI: 10.1126/scitranslmed.3001577

Ferraro F, Lymperi S, Méndez-Ferrer S, Saez B, Spencer JA, Yeap BY, Masselli E, Graiani G, Prezioso L, Rizzini EL, Mangoni M, Rizzoli V, Sykes SM, Lin CP, Frenette PS, Quaini F, Scadden DT

Diabetes impairs hematopoietic stem cell mobilization by altering niche function. Sci Transl Med. 2011;3(104):104ra101 - PMID: 21998408 - PMCID: PMC3754876 - DOI: 10.1126/scitranslmed.3002191

Wood DK, Soriano A, Mahadevan L, Higgins JM, Bhatia SN

A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease. Sci Transl Med. 2012;4(123):123ra26 - PMID: 22378926 - PMCID: PMC3633235 - DOI: 10.1126/scitranslmed.3002738

Issadore D, Chung J*, Shao H*, Liong M, Ghazani AA, Castro CM, Weissleder R*, Lee H*

Ultrasensitive Clinical Enumeration of Rare Cells ex Vivo Using a Micro-Hall Detector Sci Transl Med. 2012;4 (141):141ra92 - PMID: 22764208 - PMCID: PMC3603277 - DOI: 10.1126/scitranslmed.3003747

Ullal AV*, Peterson V*, Agasti SS, Tuang S, Juric D, Castro CM, Weissleder R

Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates Sci Transl Med. 2014;6(219):219ra9 - PMID: 24431113 - PMCID: PMC4063286 - DOI: 10.1126/scitranslmed.3007361

Kobzik L, Swirski FK

MARCOing Monocytes for Elimination. Sci Transl Med. 2014;6(219):219fs4 - PMID: 24431109 - PMCID: PMC4374341 - DOI: 10.1126/scitranslmed.3008448

Mulder WJ, Jaffer FA, Fayad ZA, Nahrendorf M

Imaging and Nanomedicine in Inflammatory Atherosclerosis. Sci Transl Med. 2014;6(239):239sr1 - PMID: 24898749 - PMCID: PMC4110972 - DOI: 10.1126/scitranslmed.3005101

Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R

Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin Sci Transl Med. 2014;6 (261):261ra152 - PMID: 25378644 - PMCID: PMC4330962 - DOI: 10.1126/scitranslmed.3009318

Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R

The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015;7(288):288ra77 - PMID: 25995223 - PMCID: PMC4675670 - DOI: 10.1126/scitranslmed.aaa3575

Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamal N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R

Predicting therapeutic nano-medicine efficacy using a companion MR imaging nanoparticle. Sci Transl Med. 2015;7:314 - PMID: 26582898 - PMCID: PMC5462466 - DOI: 10.1126/scitranslmed.aac6522

Sager HB, Dutta P, Dahlman JE, Hulsmans M, Courties G, Sun Y, Heidt T, Vinegoni C, Borodovsky A, Fitzgerald K, Wojtkiewicz GR, Iwamoto Y, Tricot B, Khan OF, Kauffman KJ, Xing Y, Shaw TE, Libby P, Langer R, Weissleder R, Swirski FK, Anderson DG, Nahrendorf M

RNAi targeting multiple cell adhesion molecules reduces immune cell recruitment and vascular inflammation after myocardial infarction Sci Transl Med. 2016;8:342 - PMID: 27280687 - PMCID: PMC5125383 - DOI: 10.1126/scitranslmed.aaf1435

Weissleder R, Schwaiger MC, Gambhir SS, Hricak H

Imaging approaches to optimize molecular therapies Sci Transl Med. 2016;8(355):355ps16 - PMID: 27605550 - DOI: 10.1126/scitranslmed.aaf3936

Malka R, Nathan DM, Higgins JM

Mechanistic modeling of hemoglobin glycation and red blood cell kinetics enables personalized diabetes monitoring Sci Transl Med. 2016;8:359ra130 - PMID: 27708063 - PMCID: PMC5714656 - DOI: 10.1126/scitranslmed.aaf9304

Castro CM

Taking cancer drug screening very personally. Sci Transl Med. 2016;8(367):367ec190 - PMID: 27903858 - DOI: 10.1126/scitranslmed.aal2799

Castro CM

Good to the last "emulsified" drop. Sci Transl Med. 2017;9(373):ePub - PMID: 28100835 - DOI: 10.1126/scitranslmed.aal4993

Miller MA

Richer data with personalized GEMs. Sci Transl Med. 2017;9(381):ePub - PMID: 28298424 - DOI: 10.1126/scitranslmed.aam9865

King KR

Squeeze-E squeeze-E. Sci Transl Med. 2017;9(382):ePub - PMID: 28330860 - DOI: 10.1126/scitranslmed.aan0766

Miller MA

Nanoparticles improve economic mileage for CARs. Sci Transl Med. 2017;9(387):ePub - PMID: 28446684 - DOI: 10.1126/scitranslmed.aan2784

King KR

Stunning neutrophils changes the forecast: No more showers. Sci Transl Med. 2017;9(388):ePub - PMID: 28469035 - DOI: 10.1126/scitranslmed.aan3775

Arlauckas SP*, Garris CS*, Kohler RH, Kitaoka M, Cuccarese MF, Yang KS, Miller MA, Carlson JC, Freeman GJ, Anthony RM, Weissleder R, Pittet MJ

In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy Sci Transl Med. 2017;9(389):eaal3604 - PMID: 28490665 - PMCID: PMC5734617 - DOI: 10.1126/scitranslmed.aal3604

Yang KS*, Im H*, Hong S, Pergolini I, Del Castillo AF, Wang R, Clardy S, Huang CH, Pille C, Ferrone S, Yang R, Castro CM, Lee H, Del Castillo CF, Weissleder R

Multiparametric plasma EV profiling facilitates diagnosis of pancreatic malignancy Sci Transl Med. 2017;9(391):eaal3226 - PMID: 28539469 - PMCID: PMC5846089 - DOI: 10.1126/scitranslmed.aal3226

Miller MA, Chandra R, Cuccarese MF, Pfirschke C, Engblom C, Stapleton S, Adhikary U, Kohler RH, Mohan JF, Pittet MJ, Weissleder R

Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts Sci Transl Med. 2017;9(392):eaal0225 - PMID: 28566423 - PMCID: PMC6681815 - DOI: 10.1126/scitranslmed.aal0225

Miller MA

Driver mutations take the wheel in invasive yet nonmalignant disease. Sci Transl Med. 2017;9(393):ePub - PMID: 28592567 - DOI: 10.1126/scitranslmed.aan8194

Miller MA

Nanotransfection brings progress that’s more than skin-deep Sci Transl Med. 2017;9(405):eaao4216

Miller MA

Counting on carbon quantum dots to clear infection Sci Transl Med. 2017;9(399):eaao0969

Miller MA

It’s what’s inside that counts for nanoparticle vaccines Sci Transl Med. 2017;9(417):eaar2438 - DOI: 10.1126/scitranslmed.aar2438

Miller MA

Less is more for anticancer therapy combinations Sci Transl Med. 2017;9 (411):aap8166 - DOI: 10.1126/scitranslmed.aap8166

Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, Wong CSF, Kloepper J, Das R, Tam A, Tanboon J, Duda DG, Miller CR, Siegel MB, Anders CK, Sanders M, Estrada MV, Schlegel R, Arteaga CL, Brachtel E, Huang A, Fukumura D, Engelman JA, Jain RK

The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation. Sci Transl Med. 2017;9(391):ePub - PMID: 28539475 - PMCID: PMC5917603 - DOI: 10.1126/scitranslmed.aal4682

Miller MA

Gold photothermal therapy: A positive for negative margins Sci Transl Med. 2018;10(423):eaar7512 - DOI: 10.1126/scitranslmed.aar7512

Binderup T, Duivenvoorden R, Fay F, van Leent MMT, Malkus J, Baxter S, Ishino S, Zhao Y, Sanchez-Gaytan B, Teunissen AJP, Frederico YCA, Tang J, Carlucci G, Lyashchenko S, Calcagno C, Karakatsanis N, Soultanidis G, Senders ML, Robson PM, Mani V, Ramachandran S, Lobatto ME, Hutten BA, Granada JF, Reiner T, Swirski FK, Nahrendorf M, Kjaer A, Fisher EA, Fayad ZA, Pérez-Medina C, Mulder WJM

Imaging-assisted nanoimmunotherapy for atherosclerosis in multiple species. Sci Transl Med. 2019;11(506):ePub - PMID: 31434756 - PMCID: PMC7328283 - DOI: 10.1126/scitranslmed.aaw7736

Naxerova K

A new function for polycomb in immune evasion Sci Transl Med. 2019;11(514):eaaz3718 - DOI: 10.1126/scitranslmed.aaz3718

Harisinghani MG, O’Shea A, Weissleder R

Advances in clinical MRI technology Sci Transl Med. 2019;11 (523):eaba2591 - PMID: 31852796 - DOI: 10.1126/scitranslmed.aba2591

Naxerova K

Tumor mutations are not alone in the plasma Sci Transl Med. 2019;11(522):eaaz9767 - DOI: 10.1126/scitranslmed.aaz9767

Naxerova K

Interrogating CD8+ T cell reactivity on a genome-wide scale Sci Transl Med. 2019;11(506):eaaz0302 - DOI: 10.1126/scitranslmed.aaz0302

Naxerova K

From micrographs to microsatellites in one bold step Sci Transl Med. 2019;11(498):eaax9570 - DOI: 10.1126/scitranslmed.aax9570

Naxerova K

Somatic mutations are improving their bad rap Sci Transl Med. 2019;11(490):eaax4871 - DOI: 10.1126/scitranslmed.aax4871

Weissleder R, Lee H, Ko J, Pittet MJ

COVID-19 diagnostics in context Sci Transl Med. 2020;12(546):eabc1931 - PMID: 32493791 - DOI: 10.1126/scitranslmed.abc1931

Min J*, Chin LK*, Oh J, Landeros C, Vinegoni C, Lee J, Lee SJ, Park JY, Liu AQ, Castro CM, Lee H, Im H, Weissleder R

CytoPAN—Portable cellular analyses for rapid point-of-care cancer diagnosis Sci Transl Med. 2020;12:eaaz9746 - PMID: 32759277 - PMCID: PMC8217912 - DOI: 10.1126/scitranslmed.aaz9746

Panizzi P, Krohn-Grimberghe M, Keliher E, Ye YX, Grune J, Frodermann V, Sun Y, Muse CG, Bushey K, Iwamoto Y, van Leent MMT, Meerwaldt A, Toner YC, Munitz J, Maier A, Soultanidis G, Calcagno C, Pérez-Medina C, Carlucci G, Riddell KP, Barney S, Horne G, Anderson B, Maddur-Appajaiah A, Verhamme IM, Bock PE, Wojtkiewicz GR, Courties G, Swirski FK, Church WR, Walz PH, Tillson DM, Mulder WJM, Nahrendorf M

Multimodal imaging of bacterial-host interface in mice and piglets with Staphylococcus aureus endocarditis. Sci Transl Med. 2020;12(568):ePub - PMID: 33148623 - PMCID: PMC7818516 - DOI: 10.1126/scitranslmed.aay2104

van Leent MMT, Beldman TJ, Toner YC, Lameijer MA, Rother N, Bekkering S, Teunissen AJP, Zhou X, van der Meel R, Malkus J, Nauta SA, Klein ED, Fay F, Sanchez-Gaytan BL, Pérez-Medina C, Kluza E, Ye YX, Wojtkiewicz G, Fisher EA, Swirski FK, Nahrendorf M, Zhang B, Li Y, Zhang B, Joosten LAB, Pasterkamp G, Boltjes A, Fayad ZA, Lutgens E, Netea MG, Riksen NP, Mulder WJM, Duivenvoorden R

Prosaposin mediates inflammation in atherosclerosis. Sci Transl Med. 2021;13(584):eabe1433 - PMID: 33692130 - PMCID: PMC8209679 - DOI: 10.1126/scitranslmed.abe1433

Garris CS, Wong JL, Ravetch JV, Knorr DA

Dendritic cell targeting with Fc-enhanced CD40 antibody agonists induces durable antitumor immunity in humanized mouse models of bladder cancer. Sci Transl Med. 2021;13(594):eabd1346 - PMID: 34011627 - PMCID: PMC8325152 - DOI: 10.1126/scitranslmed.abd1346

Yu H, Lee H, Cheong J, Woo SW, Oh J, Oh HK, Lee JH, Zheng H, Castro CM, Yoo YE, Kim MG, Cheon J, Weissleder R, Lee H

A rapid assay provides on-site quantification of tetrahydrocannabinol in oral fluid Sci Transl Med. 2021;13(616):eabe2352 - PMID: 34669441 - PMCID: PMC9126021 - DOI: 10.1126/scitranslmed.abe2352 - Cover

Weissleder R

Leveraging technology to address current and future world issues. Sci Transl Med. 2022;14(666):eabq0606 - PMID: 36223448 - DOI: 10.1126/scitranslmed.abq0606 - Cover

Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R

In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas Cancer Res. 2004;64:273-8 - PMID: 14729634 - DOI: 10.1158/0008-5472.can-03-1123

Grimm J, Perez JM, Josephson L, Weissleder R

Novel nanosensors for rapid analysis of telomerase activity Cancer Res. 2004;64:639-43 - PMID: 14744779 - DOI: 10.1158/0008-5472.can-03-2798

Zhao M, Josephson L, Tang Y, Weissleder R

Magnetic sensors for protease assays Angew Chem Int Ed Engl. 2003;42:1375-8 - PMID: 12671972 - DOI: 10.1002/anie.200390352

Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A Jr

Near-infrared fluorescent imaging of tumor apoptosis Cancer Res. 2003;63:1936-42 - PMID: 12702586

Kircher MF, Allport, JR, Graves EE, Love V, Josephson L, Lichtman AH, Weissleder R

In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors Cancer Res. 2003;63:6838-46 - PMID: 14583481

Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L

A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation Cancer Res. 2003;63:8122-5 - PMID: 14678964

Pham W, Weissleder R, Tung CH

An azulene dimer as a near-infrared quencher Angew Chem Int Ed Engl. 2002;41:3659-62, 3519 - PMID: 12370922 - DOI: 10.1002/1521-3773(20021004)41:19<3659::AID-ANIE3659>3.0.CO;2-Q

Tung CH, Mahmood U, Bredow S, Weissleder R

In vivo imaging of proteolytic enzyme activity using a novel molecular reporter Cancer Res. 2000;60:4953-8 - PMID: 10987312

Simonova M, Wall A, Weissleder R, Bogdanov A Jr

Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells Cancer Res. 2000;60:6656-62 - PMID: 11118049

Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout D, Weissleder R

In Vivo Imaging of ?-Galactosidase Activity Using Far Red Fluorescent Switch Cancer Res. 2004;64:1579-1583 - PMID: 14996712 - DOI: 10.1158/0008-5472.can-03-3226

Tsourkas A, Hofstetter O, Hofstetter H, Weissleder R, Josephson L

Magnetic Relaxation Switch Immunosensors Detect Enantiomeric Impurities Angew Chem Int Ed Engl. 2004;43(18):2395-2399 - PMID: 15114571 - DOI: 10.1002/anie.200352998

Shah K, Tung CH, Yang K, Weissleder R, Breakefield XO

Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy Cancer Res. 2004;64(9):3236-42 - PMID: 15126365 - DOI: 10.1158/0008-5472.can-03-3516

Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS

Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res. 2004;64(12):4069-77 - PMID: 15205313 - DOI: 10.1158/0008-5472.CAN-04-1243

Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R

Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res. 2004;64(17):6247-51 - PMID: 15342411 - DOI: 10.1158/0008-5472.CAN-04-0817

Montet X, Ntziachristos V, Grimm J, Weissleder R.

Tomographic Fluorescence Mapping of Tumor Targets Cancer Res. 2005;65 (14):6330-6336 - PMID: 16024635 - DOI: 10.1158/0008-5472.CAN-05-0382

Tang Y, Kim M, Carrasco D, Kung AL, Chin L, Weissleder R.

In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging Cancer Res. 2005;65(18):8324-30 - PMID: 16166309 - DOI: 10.1158/0008-5472.CAN-05-0027

Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA Jr.

Detection of Early Antiangiogenic Effects in Human Colon Adenocarcinoma Xenografts: In vivo Changes of Tumor Blood Volume in Response to Experimental VEGFR Tyrosine Kinase Inhibitor Cancer Res. 2005;65(20):9253-60 - PMID: 16230386 - DOI: 10.1158/0008-5472.CAN-03-2619

Choi YD, Weissleder R, Tung CH.

Selective antitumor effect of novel protease-mediated photodynamic agent Cancer Res. 2006;66 (14):7225-7229 - PMID: 16849570 - DOI: 10.1158/0008-5472.CAN-06-0448

Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K.

Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo Cancer Res. 2007;67 (15):7335-7342 - PMID: 17671203 - DOI: 10.1158/0008-5472.CAN-07-0077

Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K

MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell Delivered S-TRAIL in Human Gliomas. Cancer Res. 2007;67(19):8994-9000 - PMID: 17908999 - DOI: 10.1158/0008-5472.CAN-07-1045

Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Rachamimov AS, Hochberg FH, Weissleder R, Martuza RL, Chiocca EA

Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 2007;67(19):9398-406 - PMID: 17909049 - PMCID: PMC2850558 - DOI: 10.1158/0008-5472.CAN-07-1063

Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R

Detection of early prostate cancer using a hepsin-targeted imaging agent. Cancer Res. 2008;68(7):2286-91 - PMID: 18381435 - PMCID: PMC2709884 - DOI: 10.1158/0008-5472.CAN-07-1349

Koh I, Hong R, Weissleder R, Josephson L

Sensitive NMR Sensors Detect Antibodies to Influenza. Angew Chem Int Ed Engl. 2008;47(22):4119-4121 - PMID: 18428168 - PMCID: PMC2668198 - DOI: 10.1002/anie.200800069

Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Lienard D, Lejeune F, Rimoldi D, Guillaume P, Meidenbauer N, Mackensen A, Rufer N, Lubenow N, Speiser D, Cerottini J, Romero P, Pittet M

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res. 2004;64:2865-73 - PMID: 15087405 - DOI: 10.1158/0008-5472.can-03-3066

Meidenbauer N, Zippelius A, Pittet M, Laumer M, Vogl S, Heymann J, Rehli M, Seliger B, Schwarz S, Le Gal F, Dietrich P, Andreesen R, Romero P, Mackensen A

High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res. 2004;64:6319-26 - PMID: 15342421 - DOI: 10.1158/0008-5472.CAN-04-1341

Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Lienard D, Gugerli O, Ferradini L, Robert C, Avril M, Zitvogel L, Angevin E

Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res. 2004;64:2192-8 - PMID: 15026362 - DOI: 10.1158/0008-5472.can-03-2969

Valmori D, Pittet M, Vonarbourg C, Rimoldi D, Lienard D, Speiser D, Dunbar R, Cerundolo V, Cerottini J, Romero P

Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376. Cancer Res. 1999;59:4050-5 - PMID: 10463606

Valmori D, Dutoit V, Lienard D, Rimoldi D, Pittet M, Champagne P, Ellefsen K, Sahin U, Speiser D, Lejeune F, Cerottini J, Romero P

Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients. Cancer Res. 2000;60:4499-506 - PMID: 10969798

Valmori D, Pittet M, Rimoldi D, Lienard D, Dunbar R, Cerundolo V, Lejeune F, Cerottini J, Romero P

An antigen-targeted approach to adoptive transfer therapy of cancer. Cancer Res. 1999;59:2167-73 - PMID: 10232604

Kelly K, Manos E, Jensen G, Nadauld L, Jones D

APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. Cancer Res. 2000;60:1021-7 - PMID: 10706119

Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD

Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors. Cancer Res. 2009;69(8):3472-81 - PMID: 19351838 - PMCID: PMC2785462 - DOI: 10.1158/0008-5472.CAN-08-3886

Lee H*, Yoon TJ*, Weissleder R

Ultrasensitive Detection of Bacteria Using Core-Shell Nanoparticles and an NMR-Filter System. Angew Chem Int Ed Engl. 2009;48(31):5657-60 - PMID: 19554581 - PMCID: PMC2453069 - DOI: 10.1002/anie.200901791

Devaraj NK, Upadhyay R, Haun JB, Hilderbrand SA, Weissleder R

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition. Angew Chem Int Ed Engl. 2009;48(38):7013-6 - PMID: 19697389 - PMCID: PMC2790075 - DOI: 10.1002/anie.200903233

Georgakoudi I, Solban N, Novak J, Rice WL, Wei X, Hasan T, Lin CP

In vivo flow cytometry: a new method for enumerating circulating cancer cells. Cancer Res. 2004;64(15):5044-7 - PMID: 15289300 - PMCID: PMC2824432 - DOI: 10.1158/0008-5472.CAN-04-1058

Devaraj NK, Hilderbrand S, Upadhyay R, Mazitschek R, Weissleder R

Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells. Angew Chem Int Ed Engl. 2010;19 (49):2869-2872 - PMID: 20306505 - PMCID: PMC3433403 - DOI: 10.1002/anie.200906120

Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, Fisher PB, Sarkar D

Molecular Mechanism of Chemoresistance by Astrocyte Elevated Gene-1. Cancer Res. 2010;70(8):3249-58 - PMID: 20388796 - PMCID: PMC2855753 - DOI: 10.1158/0008-5472.CAN-09-4009

Taniguchi CM, Winnay J, Kondo T, Bronson RT, Guimaraes AR, Aleman JO, Luo J, Stephanopoulos G, Weissleder R, Cantley LC, Kahn CR

The Phosphoinositide 3-Kinase Regulatory Subunit p85{alpha} Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling. Cancer Res. 2010;70(13):5305-5315 - PMID: 20530665 - PMCID: PMC3204358 - DOI: 10.1158/0008-5472.CAN-09-3399

Bagci-Onder T, Wakimoto H, Anderegg M, Cameron C, Shah K

A dual PI3K/mTOR inhibitor, PI-103, cooperates with stem cell delivered TRAIL in experimental glioma models. Cancer Res. 2010;71(1):154-63 - PMID: 21084267 - DOI: 10.1158/0008-5472.CAN-10-1601

Reiner T, Keliher EJ, Earley S, Marinelli B, Weissleder R

Synthesis and In Vivo Imaging of a (18) F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method. Angew Chem Int Ed Engl. 2011;50(8):1922-5 - PMID: 21328671 - PMCID: PMC3471140 - DOI: 10.1002/anie.201006579

Yoon TJ*, Lee H*, Shao H, Weissleder R

Highly magnetic core-shell nanoparticles with a unique magnetization mechanism. Angew Chem Int Ed Engl. 2011;50(20):4663-6 - PMID: 21495138 - PMCID: PMC3334859 - DOI: 10.1002/anie.201100101

Orth JD, Kohler RH, Foijer F, Sorger PK, Weissleder R, Mitchison TJ

Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics. Cancer Res. 2011;71(13):4608-16 - PMID: 21712408 - PMCID: PMC3129392 - DOI: 10.1158/0008-5472.CAN-11-0412

Budin G, Yang KS, Reiner T, Weissleder R

Bioorthogonal Probes for Polo-like Kinase 1 Imaging and Quantification. Angew Chem Int Ed Engl. 2011;50(40):9378-81 - PMID: 21948435 - PMCID: PMC3187564 - DOI: 10.1002/anie.201103273

Agasti SS, Liong M, Tassa C, Chung HJ, Shaw SY, Lee H, Weissleder R

Supramolecular Host-Guest Interaction for Labeling and Detection of Cellular Biomarkers. Angew Chem Int Ed Engl. 2011;51(2):450-4 - PMID: 22113923 - PMCID: PMC3309171 - DOI: 10.1002/anie.201105670

Karver MR, Weissleder R, Hilderbrand SA

Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging. Angew Chem Int Ed Engl. 2011;51(4):920-2 - PMID: 22162316 - PMCID: PMC3304098 - DOI: 10.1002/anie.201104389

Rosenbaum C, Baumhof P, Mazitschek R, Müller O, Giannis A, Waldmann H

Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors. Angew Chem Int Ed Engl. 2004;43(2):224-8 - PMID: 14695616 - DOI: 10.1002/anie.200352582

Huwe A, Mazitschek R, Giannis A

Small molecules as inhibitors of cyclin-dependent kinases. Angew Chem Int Ed Engl. 2003;42(19):2122-38 - PMID: 12761741 - DOI: 10.1002/anie.200200540

Stahl P, Kissau L, Mazitschek R, Giannis A, Waldmann H

Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors. Angew Chem Int Ed Engl. 2002;41(7):1174-8 - PMID: 12491250 - DOI: 10.1002/1521-3773(20020402)41:7<1174::aid-anie1174>3.0.co;2-v

Stieber F, Mazitschek R, Soric N, Giannis A, Waldmann H

Traceless solid-phase synthesis of 2-aminothiazoles: receptor tyrosine kinase inhibitors with dual selectivity for Tie-2 and VEGFR-2. Angew Chem Int Ed Engl. 2002;41(24):4757-61 - PMID: 12481350 - DOI: 10.1002/anie.200290040

Mazitschek R, Mülbaier M, Giannis A

IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids. Angew Chem Int Ed Engl. 2002;41(21):4059-61 - PMID: 12412081 - DOI: 10.1002/1521-3773(20021104)41:21<4059::AID-ANIE4059>3.0.CO;2-R

Baumhof P, Mazitschek R, Giannis A

A Mild and Effective Method for the Transesterification of Carboxylic Acid Esters P.B. and R.M. are grateful to the Land Baden-Württemberg for a scholarship from the Landesgraduiertenförderung. Angew Chem Int Ed Engl. 2001;40(19):3672-3674 - PMID: 11592218 - DOI: 10.1002/1521-3773(20011001)40:19<3672::aid-anie3672>3.0.co;2-y

Wernert N, Stanjek A, Kiriakidis S, Hügel A, Jha HC, Mazitschek R, Giannis A

Inhibition of Angiogenesis In Vivo by ets-1 Antisense Oligonucleotides-Inhibition of Ets-1 Transcription Factor Expression by the Antibiotic Fumagillin. Angew Chem Int Ed Engl. 1999;38(21):3228-3231 - PMID: 10556911 - DOI: 10.1002/(sici)1521-3773(19991102)38:21<3228::aid-anie3228>3.0.co;2-8

Hendricks JA, Keliher EJ, Wan D, Hilderbrand SA, Weissleder R, Mazitschek R

Synthesis of [(18) F]BODIPY: Bifunctional Reporter for Hybrid Optical/Positron Emission Tomography Imaging. Angew Chem Int Ed Engl. 2012;51(19):4603-6 - PMID: 22473535 - PMCID: PMC3343182 - DOI: 10.1002/anie.201107957

Earley S, Vinegoni C, Dunham J, Gorbatov R, Fumene Feruglio P, Weissleder R

In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single cell resolution. Cancer Res. 2012;72(12):2949-56 - PMID: 22505651 - PMCID: PMC3603290 - DOI: 10.1158/0008-5472.CAN-11-4096

Yang KS, Budin G, Reiner T, Vinegoni C, Weissleder R

Bioorthogonal Imaging of Aurora Kinase A in Live Cells. Angew Chem Int Ed Engl. 2012;51(27):6598-603 - PMID: 22644700 - PMCID: PMC3523717 - DOI: 10.1002/anie.201200994

Budin G*, Chung HJ*, Lee H, Weissleder R

A Magnetic Gram Stain for Bacterial Detection. Angew Chem Int Ed Engl. 2012;51(31):7752-5 - PMID: 22744868 - PMCID: PMC3496380 - DOI: 10.1002/anie.201202982

Beck S, Bernstein BE, Campbell RM, Costello JF, Dhanak D, Ecker JR, Greally JM, Issa JP, Laird PW, Polyak K, Tycko B, Jones PA,

A Blueprint for an International Cancer Epigenome Consortium. A Report from the AACR Cancer Epigenome Task Force. Cancer Res. 2012;72(24):6319-6324 - PMID: 23188507 - DOI: 10.1158/0008-5472.CAN-12-3658

Carlson JC, Meimetis LG, Hilderbrand SA, Weissleder R

BODIPY-Tetrazine Derivatives as Superbright Bioorthogonal Turn-on Probes. Angew Chem Int Ed Engl. 2013;52(27):6917-6920 - PMID: 23712730 - PMCID: PMC3875324 - DOI: 10.1002/anie.201301100

Yang* KS, Budin* G, Tassa C, Kister O, Weissleder R

Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells Angew Chem Int Ed Engl. 2013;52(40):10593-7 - PMID: 23960025 - PMCID: PMC3856564 - DOI: 10.1002/anie.201304096

Bronisz A, Wang Y, Nowicki MO, Peruzzi P, Ansari KI, Ogawa D, Balaj L, De Rienzo G, Mineo M, Nakano I, Ostrowski MC, Hochberg F, Weissleder R, Lawler SE, Chiocca EA, Godlewski J

Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1. Cancer Res. 2013;74(3):738-50 - PMID: 24310399 - PMCID: PMC3928601 - DOI: 10.1158/0008-5472.CAN-13-2650

Meimetis LG, Carlson JC, Giedt RJ, Kohler RH, Weissleder R

Ultrafluorogenic Coumarin-Tetrazine Probes for Real-Time Biological Imaging. Angew Chem Int Ed Engl. 2014;53(29):7531-4 - PMID: 24915832 - PMCID: PMC4122131 - DOI: 10.1002/anie.201403890

Viaud S, Daillère R, Boneca IG, Lepage P, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L

Harnessing the Intestinal Microbiome for Optimal Therapeutic Immunomodulation. Cancer Res. 2014;74(16):4217-4221 - PMID: 25074615 - PMCID: PMC6700746 - DOI: 10.1158/0008-5472.CAN-14-0987

Chan CT, Qi J, Smith W, Paranal R, Mazitschek R, West N, Reeves R, Chiosis G, Schreiber SL, Bradner JE, Paulmurugan R, Gambhir SS

Syntheses and Discovery of a Novel Class of Cinnamic Hydroxamates as Histone Deacetylase (HDAC) Inhibitors by Multimodality Molecular Imaging in Living Subjects. Cancer Res. 2014;74(24):7475-86 - PMID: 25320008 - PMCID: PMC4315624 - DOI: 10.1158/0008-5472.CAN-14-0197

Tesfay L, Clausen KA, Kim JW, Hedge P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV

Hepcidin regulation in prostate and its disruption in prostate cancer. Cancer Res. 2015;75(11):2254-63 - PMID: 25858146 - PMCID: PMC4454355 - DOI: 10.1158/0008-5472.CAN-14-2465

Ricklefs F, Mineo M, Rooj AK, Nakano I, Charest A, Weissleder R, Breakefield XO, Chiocca EA, Godlewski J, Bronisz A

Extracellular vesicles from high grade glioma exchange diverse pro-oncogenic signals that maintain intratumoral heterogeneity. Cancer Res. 2016;76(10):2876-2881 - PMID: 27013191 - PMCID: PMC4873326 - DOI: 10.1158/0008-5472.CAN-15-3432

Josephson L, Perez JM, Weissleder R

Magnetic Nanosensors for the Detection of Oligonucleotide Sequences. Angew Chem Int Ed Engl. 2001;40(17):3204-3206 - PMID: 29712059 - DOI: 10.1002/1521-3773(20010903)40:17<3204::AID-ANIE3204>3.0.CO;2-H

Choudhary A, Manna D, Maji B, Gangopadhyay SA, Cox KJ, Zhou Q, Law B, Mazitschek R

A singular system with precise dosing and spatiotemporal control of CRISPR-Cas9. Angew Chem Int Ed Engl. 2019;58(19):6285-6289 - PMID: 30834641 - PMCID: PMC7067309 - DOI: 10.1002/anie.201900788

Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R

Ultra-fast cycling for multiplexed cellular fluorescence imaging. Angew Chem Int Ed Engl. 2020;59(17):6839-6846 - PMID: 32004403 - PMCID: PMC11853113 - DOI: 10.1002/anie.201915153

Lyford-Pike S, Peng S, Young GD, Taube JM, Westra WH, Akpeng B, Bruno TC, Richmon JD, Wang H, Bishop JA, Chen L, Drake CG, Topalian SL, Pardoll DM, Pai SI

Evidence for a role of the PD-1:PD-L1 pathway in immune resistance of HPV-associated head and neck squamous cell carcinoma. Cancer Res. 2013;73(6):1733-41 - PMID: 23288508 - PMCID: PMC3602406 - DOI: 10.1158/0008-5472.CAN-12-2384

Mattox AK, Lee J, Westra WH, Pierce RH, Ghossein R, Faquin WC, Diefenbach TJ, Morris LG, Lin DT, Wirth LJ, Lefranc-Torres A, Ishida E, Chakravarty PD, Johnson L, Zeng YC, Chen H, Poznansky MC, Iyengar NM, Pai SI

PD-1 Expression in Head and Neck Squamous Cell Carcinomas Derives Primarily from Functionally Anergic CD4+ TILs in the Presence of PD-L1+ TAMs. Cancer Res. 2017;77(22):6365-6374 - PMID: 28947422 - PMCID: PMC5690870 - DOI: 10.1158/0008-5472.CAN-16-3453

Kang TH, Noh KH, Kim JH, Bae HC, Lin KY, Monie A, Pai SI, Hung CF, Wu TC, Kim TW

Ectopic expression of X-linked lymphocyte-regulated protein pM1 renders tumor cells resistant to antitumor immunity. Cancer Res. 2010;70(8):3062-70 - PMID: 20395201 - PMCID: PMC2861497 - DOI: 10.1158/0008-5472.CAN-09-3856

Kang TH, Lee JH, Song CK, Han HD, Shin BC, Pai SI, Hung CF, Trimble C, Lim JS, Kim TW, Wu TC

Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination. Cancer Res. 2007;67(2):802-11 - PMID: 17234792 - PMCID: PMC3181129 - DOI: 10.1158/0008-5472.CAN-06-2638

Pai SI, Wu GS, Ozören N, Wu L, Jen J, Sidransky D, El-Deiry WS

Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 1998;58(16):3513-8 - PMID: 9721851

Halabi EA, Gessner I, Yang K, Kim JJ, Jana R, Peterson HM, Spitzberg J, Weissleder R

Magnetic Silica-Coated Fluorescent Microspheres (MagSiGlow) for Simultaneous Detection of Tumor-Associated Proteins. Angew Chem Int Ed Engl. 2024;63(24):e202318870 - PMID: 38578432 - PMCID: PMC11998990 - DOI: 10.1002/anie.202318870

Rodriguez-Castellanos VE, Quintana JM, Martin JM, Goemans MA, Banla LI, Ng TSC, Weissleder R, Miller MA

Radiation-Triggered Payload Release Enhances Bispecific Antibody Efficacy. Cancer Res. 2025;:ePub - PMID: 41066595 - DOI: 10.1158/0008-5472.CAN-25-0517

Tozzo V, Genco M, Omololu SO, Mow C, Patel HR, Patel CH, Ho SN, Lam E, Abdulsater B, Patel N, Cohen RM, Nathan DM, Powe CE, Wexler DJ, Higgins JM

Estimating Glycemia From HbA1c and CGM: Analysis of Accuracy and Sources of Discrepancy. Diabetes Care. 2024;47(3):460-466 - PMID: 38394636 - PMCID: PMC10909686 - DOI: 10.2337/dc23-1177

Insin N, Tracy JB, Lee H, Zimmer JP, Westervelt RM, Bawendi MG

Incorporation of iron oxide nanoparticles and quantum dots into silica microspheres. ACS Nano. 2008;2(2):197-202 - PMID: 19206619 - DOI: 10.1021/nn700344x

Fourches D, Pu D, Tassa C, Weissleder R, Shaw SY, Mumper RJ, Tropsha A

Quantitative Nanostructure-Activity Relationship Modeling. ACS Nano. 2010;4(10):5703-12 - PMID: 20857979 - PMCID: PMC2997621 - DOI: 10.1021/nn1013484

Haun J, Devaraj NK, Marinelli B, Lee H, Weissleder R

Probing Intracellular Biomarkers and Mediators of Cell Activation Using Nanosensors and Bioorthogonal Chemistry. ACS Nano. 2011;5(4):3204-13 - PMID: 21351804 - PMCID: PMC3088084 - DOI: 10.1021/nn200333m

Chung H, Reiner T, Budin G, Min C, Liong M, Issadore D, Lee H, Weissleder R

Ubiquitous Detection of Gram-Positive Bacteria with Bioorthogonal Magnetofluorescent Nanoparticles. ACS Nano. 2011;5(11):8834-41 - PMID: 21967150 - PMCID: PMC3222727 - DOI: 10.1021/nn2029692

Ullal AV, Reiner T, Yang KS, Gorbatov R, Min C, Issadore D, Lee H, Weissleder R

Nanoparticle Mediated Measurement of Target-Drug Binding in Cancer Cells. ACS Nano. 2011;5(11):9216-24 - PMID: 21962084 - PMCID: PMC3297118 - DOI: 10.1021/nn203450p

Peterson VM, Castro CM, Lee H, Weissleder R

Orthogonal Amplification of Nanoparticles for Improved Diagnostic Sensing. ACS Nano. 2012;6(4):3506-13 - PMID: 22424443 - PMCID: PMC3337350 - DOI: 10.1021/nn300536y

Min C, Shao H, Liong M, Yoon TJ, Weissleder R, Lee H

Mechanism of Magnetic Relaxation Switching Sensing. ACS Nano. 2012;6(8):6821-8 - PMID: 22762250 - PMCID: PMC3429660 - DOI: 10.1021/nn301615b

Rho J, Chung J, Im H, Liong M, Shao H, Castro CM, Weissleder R, Lee H

Magnetic Nanosensor for Detection and Profiling of Erythrocyte-Derived Microvesicles. ACS Nano. 2013;7(12):11227-33 - PMID: 24295203 - PMCID: PMC3898036 - DOI: 10.1021/nn405016y

Lai CP, Mardini O, Ericsson M, Prabhakar S, Maguire C, Chen JW, Tannous BA, Breakefield XO

Dynamic Biodistribution of Extracellular Vesicles In Vivo Using a Multimodal Imaging Reporter. ACS Nano. 2014;8(1):483-94 - PMID: 24383518 - PMCID: PMC3934350 - DOI: 10.1021/nn404945r

Lee K, Shao H, Weissleder R, Lee H

Acoustic Purification of Extracellular Microvesicles. ACS Nano. 2015;9(3):2321-7 - PMID: 25672598 - PMCID: PMC4373978 - DOI: 10.1021/nn506538f

Nair AV, Keliher EJ, Core AB, Brown D, Weissleder R

Characterizing the Interactions of Organic Nanoparticles with Renal Epithelial Cells in Vivo. ACS Nano. 2015;9(4):3641-53 - PMID: 25790730 - PMCID: PMC4414893 - DOI: 10.1021/acsnano.5b00428

Jeong S, Park J, Pathania D, Castro CM, Weissleder R, Lee H

Integrated Magneto-Electrochemical Sensor for Exosome Analysis. ACS Nano. 2016;10(2):1802-1809 - PMID: 26808216 - PMCID: PMC4802494 - DOI: 10.1021/acsnano.5b07584

Seo KJ, Qiang Y, Bilgin I, Kar S, Vinegoni C, Weissleder R, Fang H

Transparent Electrophysiology Microelectrodes and Interconnects from Metal Nanomesh. ACS Nano. 2017;11(4):4365-4372 - PMID: 28391679 - DOI: 10.1021/acsnano.7b01995

Wittenberg NJ, Im H, Johnson TW, Xu X, Warrington AE, Rodriguez M, Oh SH

Facile assembly of micro- and nanoarrays for sensing with natural cell membranes. ACS Nano. 2011;5(9):7555-64 - PMID: 21842844 - PMCID: PMC3183111 - DOI: 10.1021/nn202554t

Im H, Lee SH, Wittenberg NJ, Johnson TW, Lindquist NC, Nagpal P, Norris DJ, Oh SH

Template-stripped smooth Ag nanohole arrays with silica shells for surface plasmon resonance biosensing. ACS Nano. 2011;5(8):6244-53 - PMID: 21770414 - PMCID: PMC3160512 - DOI: 10.1021/nn202013v

Im H, Lindquist NC, Lesuffleur A, Oh SH

Atomic layer deposition of dielectric overlayers for enhancing the optical properties and chemical stability of plasmonic nanoholes. ACS Nano. 2010;4(2):947-54 - PMID: 20131870 - DOI: 10.1021/nn901842r

Lin HY, Huang CH, Park J, Pathania D, Castro CM, Fasano A, Weissleder R, Lee H

Integrated Magneto-Chemical Sensor For On-Site Food Allergen Detection. ACS Nano. 2017;11(10):10062-10069 - PMID: 28792732 - DOI: 10.1021/acsnano.7b04318

Park J, Lin HY, Assaker JP, Jeong S, Huang CH, Kurdi A, Lee K, Fraser K, Min C, Eskandari S, Routray S, Tannous BA, Abdi R, Riella L, Chandraker A, Castro CM, Weissleder R, Lee H, Azzi JR

Integrated Kidney Exosome Analysis (iKEA) For The Detection Of Kidney Transplant Rejection. ACS Nano. 2017;11(11):11041-11046 - PMID: 29053921 - PMCID: PMC6237084 - DOI: 10.1021/acsnano.7b05083

Park K, Kim H, Kim S, Lee K, Park S, Song J, Min C, Khanam F, Rashu R, Bhuiyan TR, Ryan ET, Qadri F, Weissleder R, Cheon J, Charles RC, Lee H

Nano-Magnetic System For Rapid Diagnosis Of Acute Infection. ACS Nano. 2017;11(11):11425-11432 - PMID: 29121461 - PMCID: PMC6296367 - DOI: 10.1021/acsnano.7b06074

Lee K, Fraser K, Ghaddar B, Yang K, Kim E, Balaj L, Chiocca A, Breakefield XO, Lee H, Weissleder R

Multiplexed Profiling of Single Extracellular Vesicles. ACS Nano. 2018;12(1):494-503 - PMID: 29286635 - PMCID: PMC5898240 - DOI: 10.1021/acsnano.7b07060

Min J, Nothing M, Coble B, Zheng H, Park J, Im H, Weber GF, Castro CM, Swirski FK, Weissleder R, Lee H

Integrated Biosensor for Rapid and Point-Of-Care Sepsis Diagnosis. ACS Nano. 2018;12(4):3378-3384 - PMID: 29533646 - PMCID: PMC6019292 - DOI: 10.1021/acsnano.7b08965

Min J, Im H, Allen M, McFarland PJ, Degani I, Yu H, Normandin E, Pathania D, Patel J, Castro CM, Weissleder R, Lee H

Computational Optics Enables Breast Cancer Profiling in Point-Of-Care Settings. ACS Nano. 2018;12(9):9081-9090 - PMID: 30113824 - PMCID: PMC6519708 - DOI: 10.1021/acsnano.8b03029

Kim HY, Li R, Ng TSC, Courties G, Rodell CB, Prytyskach M, Kohler RH, Pittet M, Nahrendorf M, Weissleder R, Miller MA

Quantitative Imaging of Tumor Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin. ACS Nano. 2018;12(12):12015-12029 - PMID: 30508377 - PMCID: PMC6482841 - DOI: 10.1021/acsnano.8b04338

Miller MA, Mikula H, Luthria G, Li R, Kronister S, Prytyskach M, Kohler RH, Mitchison T, Weissleder R

Modular Nanoparticulate Prodrug Design Enables Efficient Treatment of Solid Tumors Using Bioorthogonal Activation. ACS Nano. 2018;12(12):12814-12826 - PMID: 30550257 - PMCID: PMC6307086 - DOI: 10.1021/acsnano.8b07954

Erel-Akbaba G, Carvalho LA, Tian T, Zinter M, Akbaba H, Obeid PJ, Chiocca EA, Weissleder R, Kantarci AG, Tannous BA

Radiation-Induced Targeted Nanoparticle- Based Gene Delivery for Brain Tumor Therapy ACS Nano. 2019;13(4):4028-4040 - PMID: 30916923 - PMCID: PMC7104714 - DOI: 10.1021/acsnano.8b08177

Huang CH, Park YI, Lin HY, Pathania D, Park KS, Avila-Wallace M, Castro CM, Weissleder R, Lee H

Compact and Filter-Free Luminescence Biosensor for Mobile In-Vitro Diagnoses. ACS Nano. 2019;13(10):11698-11706 - PMID: 31461265 - PMCID: PMC7307311 - DOI: 10.1021/acsnano.9b05634

Chin LK*, Son T*, Hong JS, Liu AQ, Skog J, Castro CM, Weissleder R, Lee H*, Im H*

Plasmonic Sensors for Extracellular Vesicle Analysis: From Scientific Development to Translational Research. ACS Nano. 2020;14(11):14528-14548 - PMID: 33119256 - PMCID: PMC8423498 - DOI: 10.1021/acsnano.0c07581

Ko J*, Wang Y*, Sheng K, Weitz DA, Weissleder R

Sequencing-Based Protein Analysis of Single Extracellular Vesicles ACS Nano. 2021;15(3):5631-5638 - PMID: 33687214 - PMCID: PMC8742254 - DOI: 10.1021/acsnano.1c00782

Tian T, Liang R, Erel-Akbaba G, Saad L, Obeid PJ, Gao J, Chiocca EA, Weissleder R, Tannous BA

Immune Checkpoint Inhibition in GBM Primed with Radiation by Engineered Extracellular Vesicles. ACS Nano. 2022;16(2):1940-1953 - PMID: 35099172 - PMCID: PMC9020451 - DOI: 10.1021/acsnano.1c05505

Chin LK, Yang JY, Chousterman B, Jung S, Kim DG, Kim DH, Lee S, Castro CM, Weissleder R, Park SG, Im H

Dual-Enhanced Plasmonic Biosensing for Point-of-Care Sepsis Detection. ACS Nano. 2023;17(4):3610-3619 - PMID: 36745820 - PMCID: PMC10150330 - DOI: 10.1021/acsnano.2c10371

Fredrich IR*, Halabi EA*, Kohler RH, Ge X, Garris CS, Weissleder R

Highly Active Myeloid Therapy for Cancer. ACS Nano. 2023;17(20):20666-20679 - PMID: 37824733 - PMCID: PMC10941024 - DOI: 10.1021/acsnano.3c08034

Tran HL, Zheng W, Issadore DA, Im H, Cho YK, Zhang Y, Liu D, Liu Y, Li B, Liu F, Wong DTW, Sun J, Qian K, He M, Wan M, Zeng Y, Cheng K, Huang TJ, Chiu DT, Lee LP, Zheng L, Godwin AK, Kalluri R, Soper SA, Hu TY

Extracellular Vesicles for Clinical Diagnostics: From Bulk Measurements to Single-Vesicle Analysis. ACS Nano. 2025;19(31):28021-28109 - PMID: 40720603 - PMCID: PMC12356129 - DOI: 10.1021/acsnano.5c00706

Kim HS, Simpson GG, Carrothers J, Nguyen YTM, Kohler R, Hong S, Cha S, Kim DH, Garris CS, Weissleder R

A Myeloid Cell-Targeted Immunostimulant Cocktail (MyTai) Enhances Cancer Immunotherapy. ACS Nano. 2025;19(41):36451-36464 - PMID: 41061756 - DOI: 10.1021/acsnano.5c10081

Jaffer FA, Weissleder R

Seeing within: molecular imaging of the cardiovascular system Circ Res. 2004;94(4):433-45 - PMID: 15001542 - DOI: 10.1161/01.RES.0000119321.18573.5A

Kelly KA, Allport JR, Tsourkas A, Shinde-Patil VR, Josephson L, Weissleder R.

Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle Circ Res. 2005;96(3):327-36 - PMID: 15653572 - DOI: 10.1161/01.RES.0000155722.17881.dd

Nahrendorf M, Sosnovik D, Waterman P, Swirski F, Pande A, Aikawa E, Figueiredo JL, Pittet M, Weissleder R.

Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct Circ Res. 2007;100:1218-1225 - PMID: 17379832 - DOI: 10.1161/01.RES.0000265064.46075.31

Paruchuri S, Yang J, Aikawa E, Melero-Martin J, Khan Z, Loukogeorgakis S, Schoen F, Bischoff J

Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-{beta}2. Circ Res. 2006;99(8):861-9 - PMID: 16973908 - PMCID: PMC2810464 - DOI: 10.1161/01.RES.0000245188.41002.2c

Aikawa M, Rabkin E, Voglic S, Shing H, Nagai R, Schoen F, Libby P

Lipid lowering promotes accumulation of mature smooth muscle cells expressing smooth muscle myosin heavy chain isoforms in rabbit atheroma. Circ Res. 1998;83:1015-26 - PMID: 9815149 - DOI: 10.1161/01.res.83.10.1015

Leuschner F, Panizzi P, Chico-Calero I, Lee WW, Ueno T, Cortez-Retamozo V, Waterman P, Gorbatov R, Marinelli B, Iwamoto Y, Chudnovskiy A, Figueiredo JL, Sosnovik DE, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M

Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction. Circ Res. 2010;107(11):1364-73 - PMID: 20930148 - PMCID: PMC2992104 - DOI: 10.1161/CIRCRESAHA.110.227454

Leuschner F, Nahrendorf M

Molecular imaging of coronary atherosclerosis and myocardial infarction: considerations for the bench and perspectives for the clinic. Circ Res. 2011;108(5):593-606 - PMID: 21372291 - PMCID: PMC3397211 - DOI: 10.1161/CIRCRESAHA.110.232678

Nahrendorf M, McCarthy JR, Libby P

Over a hump for imaging atherosclerosis: nanobodies visualize vascular cell adhesion molecule-1 in inflamed plaque. Circ Res. 2012;110(7):902-3 - PMID: 22461358 - DOI: 10.1161/CIRCRESAHA.112.267260

Courties G, Nahrendorf M

Enlightened stem cells in the heart: more efficient and safer reporter gene imaging. Circ Res. 2012;111(12):1486-7 - PMID: 23223928 - DOI: 10.1161/CIRCRESAHA.112.280982

Majmudar MD, Yoo J, Keliher E, Truelove JJ, Iwamoto Y, Sena B, Dutta P, Borodovsky A, Fitzgerald K, Di Carli MF, Libby P, Anderson D, Swirski FK, Weissleder R, Nahrendorf M

Polymeric Nanoparticle PET/MR Imaging Allows Macrophage Detection in Atherosclerotic Plaques. Circ Res. 2013;112(5):755-61 - PMID: 23300273 - PMCID: PMC3586287 - DOI: 10.1161/CIRCRESAHA.111.300576

Jung K, Kim P, Leuschner F, Gorbatov R, Kim JK, Ueno T, Nahrendorf M, Yun SH

Endoscopic Time-Lapse Imaging of Immune Cells in Infarcted Mouse Hearts. Circ Res. 2013;112(6):891-899 - PMID: 23392842 - PMCID: PMC3834270 - DOI: 10.1161/CIRCRESAHA.111.300484

Swirski FK, Robbins CS

Neutrophils usher monocytes into sites of inflammation. Circ Res. 2013;112(5):744-5 - PMID: 23449542 - DOI: 10.1161/CIRCRESAHA.113.300867

Nahrendorf M, Swirski FK

Monocyte and macrophage heterogeneity in the heart. Circ Res. 2013;112(12):1624-33 - PMID: 23743228 - PMCID: PMC3753681 - DOI: 10.1161/CIRCRESAHA.113.300890

Nahrendorf M, Swirski FK

Fluorescent leukocytes enter plaque on the microscope stage. Circ Res. 2014;114(5):740-1 - PMID: 24577957 - PMCID: PMC3957183 - DOI: 10.1161/CIRCRESAHA.114.303520

Hilgendorf I, Gerhardt L, Tan TC, Winter C, Holderried TA, Chousterman BG, Iwamoto Y, Liao R, Zirlik A, Scherrer-Crosbie M, Hedrick CC, Libby P, Nahrendorf M, Weissleder R, Swirski FK

Ly-6Chigh Monocytes Depend on Nr4a1 to Balance both Inflammatory and Reparative Phases in the Infarcted Myocardium. Circ Res. 2014;114(10):1611-22 - PMID: 24625784 - PMCID: PMC4017349 - DOI: 10.1161/CIRCRESAHA.114.303204

Heidt T, Courties G, Dutta P, Sager H, Sebas M, Iwamoto Y, Sun Y, Da Silva N, Panizzi P, van der Laan AM, Swirski FK, Weissleder R, Nahrendorf M

Differential Contribution of Monocytes to Heart Macrophages in Steady-State and After Myocardial Infarction. Circ Res. 2014;115(2):284-95 - PMID: 24786973 - PMCID: PMC4082439 - DOI: 10.1161/CIRCRESAHA.115.303567

Nahrendorf M, Swirski FK

Regulating repair: regulatory T cells in myocardial infarction. Circ Res. 2014;115(1):7-9 - PMID: 24951758 - PMCID: PMC4094354 - DOI: 10.1161/CIRCRESAHA.114.304295

Swirski FK, Nahrendorf M

Do vascular smooth muscle cells differentiate to macrophages in atherosclerotic lesions? Circ Res. 2014;115(7):605-6 - PMID: 25214571 - PMCID: PMC4166538 - DOI: 10.1161/CIRCRESAHA.114.304925

Courties G, Herisson F, Sager H, Heidt T, Ye Y, Ying W, Sun Y, Severe N, Dutta P, Scharff J, Scadden D, Weissleder R, Swirski FK, Moskowitz MA, Nahrendorf M

Ischemic Stroke Activates Hematopoietic Bone Marrow Stem Cells. Circ Res. 2015;116(3):407-17 - PMID: 25362208 - PMCID: PMC4312511 - DOI: 10.1161/CIRCRESAHA.116.305207

Nahrendorf M, Swirski FK

Lifestyle Effects on Hematopoiesis and Atherosclerosis. Circ Res. 2015;116(5):884-894 - PMID: 25722442 - PMCID: PMC4347940 - DOI: 10.1161/CIRCRESAHA.116.303550

Konishi M, Erdem SS, Weissleder R, Lichtman AH, McCarthy J, Libby P

Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis. Circ Res. 2015;117(6):502-12 - PMID: 26199323 - PMCID: PMC4553143 - DOI: 10.1161/CIRCRESAHA.115.306364

Ye YX, Calcagno C, Binderup T, Courties G, Keliher E, Wojtkiewicz GR, Iwamoto Y, Tang J, Perez-Medina C, Mani V, Ishino S, Johnbeck CB, Knigge U, Fayad ZA, Libby P, Weissleder R, Tawakol A, Dubey S, Belanger AP, Di Carli MF, Swirski FK, Kjær A, Mulder W, Nahrendorf M

Imaging Macrophage and Hematopoietic Progenitor Proliferation in Atherosclerosis. Circ Res. 2015;117(10):835-45 - PMID: 26394773 - PMCID: PMC4619168 - DOI: 10.1161/CIRCRESAHA.115.307024

McAlpine CS, Swirski FK

Circadian Influence on Metabolism and Inflammation in Atherosclerosis. Circ Res. 2016;119(1):131-41 - PMID: 27340272 - PMCID: PMC4922503 - DOI: 10.1161/CIRCRESAHA.116.308034

Sager HB, Hulsmans M, Lavine KJ, Beltrami Moreira MB, Heidt T, Courties G, Sun Y, Iwamoto Y, Tricot B, Khan OF, Dahlman JE, Borodovsky A, Fitzgerald K, Anderson DG, Weissleder R, Libby P, Swirski FK, Nahrendorf M

Proliferation and Recruitment Contribute to Myocardial Macrophage Expansion in Chronic Heart Failure. Circ Res. 2016;119(7):853-64 - PMID: 27444755 - PMCID: PMC5378496 - DOI: 10.1161/CIRCRESAHA.116.309001

Nahrendorf M, Swirski FK

Abandoning M1/M2 for a Network Model of Macrophage Function. Circ Res. 2016;119(3):414-7 - PMID: 27458196 - PMCID: PMC4965179 - DOI: 10.1161/CIRCRESAHA.116.309194

Swirski FK, Nahrendorf M

Bone Marrow Takes Center Stage in Cardiovascular Disease. Circ Res. 2016;119(6):701-3 - PMID: 27587406 - PMCID: PMC5012290 - DOI: 10.1161/CIRCRESAHA.116.309584

Honold L, Nahrendorf M

Resident and Monocyte-Derived Macrophages in Cardiovascular Disease. Circ Res. 2018;122(1):113-127 - PMID: 29301844 - PMCID: PMC5777215 - DOI: 10.1161/CIRCRESAHA.117.311071

Franck G, Mawson T, Sausen G, Salinas M, Masson GS, Cole A, Beltrami-Moreira M, Chatzizisis Y, Quillard T, Tesmenitsky Y, Shvartz E, Sukhova GK, Swirski FK, Nahrendorf M, Aikawa E, Croce KJ, Libby P

Flow Perturbation Mediates Neutrophil Recruitment and Potentiates Endothelial Injury via TLR2 in Mice: Implications for Superficial Erosion. Circ Res. 2017;121(1):31-42 - PMID: 28428204 - PMCID: PMC5488735 - DOI: 10.1161/CIRCRESAHA.117.310694

Loyer X, Zlatanova I, Devue C, Yin M, Howangyin KY, Klaihmon P, Guerin CL, Kheloufi M, Vilar J, Zannis K, Fleischmann BK, Hwang DW, Park J, Lee H, Menasche P, Silvestre JS, Boulanger CM

Intra-Cardiac Release of Extracellular Vesicles Shapes Inflammation Following Myocardial Infarction. Circ Res. 2018;123(1):100-106 - PMID: 29592957 - PMCID: PMC6023578 - DOI: 10.1161/CIRCRESAHA.117.311326

Vandoorne K, Rohde D, Kim HY, Courties G, Wojtkiewicz GR, Honold L, Hoyer FF, Frodermann V, Nayar R, Herisson FE, Jung Y, Désogère P, Vinegoni C, Caravan P, Weissleder R, Sosnovik DE, Lin CP, Swirski FK, Nahrendorf M

Imaging the Vascular Bone Marrow Niche During Inflammatory Stress. Circ Res. 2018;123(4):415-427 - PMID: 29980569 - PMCID: PMC6202141 - DOI: 10.1161/CIRCRESAHA.118.313302

Swirski FK

A CRISPR Take on Clonal Hematopoiesis. Circ Res. 2018;123(3):313-314 - PMID: 30026373 - DOI: 10.1161/CIRCRESAHA.118.313347

Hulsmans M, Aguirre AD, Bonner M, Bapat A, Cremer S, Iwamoto Y, King KR, Swirski FK, Milan DJ, Weissleder R, Nahrendorf M

Miniaturized, Programmable Pacemaker for Long-Term Studies in the Mouse Circ Res. 2018;123(11):1208-1219 - PMID: 30571465 - PMCID: PMC6309285 - DOI: 10.1161/CIRCRESAHA.118.313429

Courties G, Frodermann V, Honold L, Zheng Y, Herisson FE, Schloss MJ, Sun Y, Presumey J, Severe N, Engblom C, Hulsmans M, Cremer S, Rohde D, Pittet MJ, Scadden D, Swirski FK, Kim DE, Moskowitz MA, Nahrendorf M

Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke. Circ Res. 2019;124(9):1372-1385 - PMID: 30782088 - PMCID: PMC6483874 - DOI: 10.1161/CIRCRESAHA.118.314518

Hulsmans M, Nahrendorf M

Smad3 Cranks Up the Appetite of Infarct Macrophages. Circ Res. 2019;125(1):71-73 - PMID: 31219739 - PMCID: PMC6588180 - DOI: 10.1161/CIRCRESAHA.119.315306

Poller WC, Nahrendorf M, Swirski FK

Hematopoiesis and Cardiovascular Disease. Circ Res. 2020;126(8):1061-1085 - PMID: 32271679 - PMCID: PMC7153537 - DOI: 10.1161/CIRCRESAHA.120.315895

Schloss MJ, Swirski FK, Nahrendorf M

Modifiable Cardiovascular Risk, Hematopoiesis, and Innate Immunity. Circ Res. 2020;126(9):1242-1259 - PMID: 32324501 - PMCID: PMC7185037 - DOI: 10.1161/CIRCRESAHA.120.315936

Kim K, Lee B, Park JH, Park JH, Lee KJ, Kwak TJ, Son T, Shin YB, Im H, Kim MG

Rapid PCR kit: lateral flow paper strip with Joule heater for SARS-CoV-2 detection. Mater Horiz. 2023;10(5):1697-1704 - PMID: 36843375 - DOI: 10.1039/d2mh01267g

Taboada E, Solanas R, Rodriguez E, Weissleder R, Roig A

Supercritical-Fluid-Assisted One-Pot Synthesis of Biocompatible Core (γ-Fe2O3)/Shell(SiO2) Nanoparticles as High Relaxivity T2-Contrast Agents for Magnetic Resonance Imaging Adv Funct Mater. 2009;19 :2319-2324

Lee S, Johnson TW, Lindquist NC, Im H, Norris DJ, Oh SH

Linewidth-Optimized Extraordinary Optical Transmission in Water with Template-Stripped Metallic Nanohole Arrays Adv Funct Mater. 2012;22(21):4439-4446

Park SG, Xiao X, Min J, Mun CW, Jung HS, Giannini V, Weissleder R, Maier SA, Im H, Kim DH

Self‐Assembly of Nanoparticle‐Spiked Pillar Arrays for Plasmonic Biosensing Adv Funct Mater. 2019;29(43):1904257 - DOI: 10.1002/adfm.201904257

Li R, Ng TSC, Garlin MA, Weissleder R*, Miller MA*

Understanding the In Vivo Fate of Advanced Materials by Imaging Adv Funct Mater. 2020;30(37):ePub - PMID: 38545084 - PMCID: PMC10972611 - DOI: 10.1002/adfm.201910369

Wang Z, Shin J, Park JH, Lee H, Kim DH, Liu H

Engineering Materials for Electrochemical Sweat Sensing Adv Funct Mater. 2021;:ePub - DOI: 10.1002/adfm.202008130

Perez JM, Simeone FJ, Saeki Y, Josephson L, Weissleder R

Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media J Am Chem Soc. 2003;125:10192-3 - PMID: 12926940 - DOI: 10.1021/ja036409g

Perez JM, O'Loughin T, Simeone F J, Weissleder R, Josephson L

DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents J Am Chem Soc. 2002;124:2856-7 - PMID: 11902860 - DOI: 10.1021/ja017773n

E.C. Wiener, F.P. Auteri, J.W. Chen, M.W. Brechbiel, O.A. Gansow, D.J. Schneider, R.L. Belford, R.B. Clarkson, P.C. Lauterbur

Molecular Dynamics of Ion-Chelate Complexes Attached to Starburst(TM) Dendrimers J Am Chem Soc. 1996;118:7774-7782

Hilderbrand S, Lim M, Lippard S

Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. J Am Chem Soc. 2004;126:4972-8 - PMID: 15080703 - DOI: 10.1021/ja038471j

Panizzi P, Nahrendorf M, Wildgruber M, Waterman P, Figueiredo JL, Aikawa E, McCarthy J, Weissleder R, Hilderbrand SA

Oxazine Conjugated Nanoparticle Detects in Vivo Hypochlorous Acid and Peroxynitrite Generation. J Am Chem Soc. 2009;131(43):15739-44 - PMID: 19817443 - PMCID: PMC2773134 - DOI: 10.1021/ja903922u

Rodriguez E, Nilges M, Weissleder R, Chen JW

Activatable magnetic resonance imaging agents for myeloperoxidase sensing: mechanism of activation, stability, and toxicity. J Am Chem Soc. 2010;132(1):168-77 - PMID: 19968300 - PMCID: PMC2802665 - DOI: 10.1021/ja905274f

Han HS, Devaraj NK, Lee J, Hilderbrand SA, Weissleder R, Bawendi MG

Development of a Bioorthogonal and Highly Efficient Conjugation Method for Quantum Dots Using Tetrazine-Norbornene Cycloaddition. J Am Chem Soc. 2010;132(23):7838-9 - PMID: 20481508 - PMCID: PMC2892974 - DOI: 10.1021/ja101677r

Brueckner C, Gotz DC, Fox SP, Ryppa C, McCarthy JR, Bruhn T, Akhigbe J, Banerjee S, Daddario P, Daniell HW, Zeller M, Boyle R, Bringmann G

Helimeric Porphyrinoids: Stereostructure and Chiral Resolution of meso-Tetraarylmorpholinochlorins. J Am Chem Soc. 2011;133(22):8740-8752 - PMID: 21534626 - DOI: 10.1021/ja202451t

Stahl P, Kissau L, Mazitschek R, Huwe A, Furet P, Giannis A, Waldmann H

Total synthesis and biological evaluation of the nakijiquinones. J Am Chem Soc. 2001;123(47):11586-93 - PMID: 11716712 - DOI: 10.1021/ja011413i

Niers JM*, Chen JW*, Lewandrowski G, Kerami M, Garanger E, Wojtkiewicz G, Waterman P, Keliher E, Weissleder R, Tannous BA

Single Reporter for Targeted Multimodal in Vivo Imaging. J Am Chem Soc. 2012;134(11):5149-56 - PMID: 22397453 - PMCID: PMC3310895 - DOI: 10.1021/ja209868g

Agasti SS, Liong M, Peterson VM, Lee H, Weissleder R

Photocleavable DNA barcode-antibody conjugates allow sensitive and multiplexed protein analysis in single cell. J Am Chem Soc. 2012;134(45):18499-18502 - PMID: 23092113 - PMCID: PMC3498844 - DOI: 10.1021/ja307689w

Chen YC, Backus KM, Merkulova M, Yang C, Brown D, Cravatt BF, Zhang C

Covalent Modulators of the Vacuolar ATPase. J Am Chem Soc. 2016;139(2):639-642 - PMID: 28010062 - PMCID: PMC5274637 - DOI: 10.1021/jacs.6b12511

Chen CH, Sarkar A, Song YA, Miller MA, Kim SJ, Griffith LG, Lauffenburger DA, Han J

Enhancing protease activity assay in droplet-based microfluidics using a biomolecule concentrator. J Am Chem Soc. 2011;133(27):10368-71 - PMID: 21671557 - PMCID: PMC3165005 - DOI: 10.1021/ja2036628

Chen CH, Miller MA, Sarkar A, Beste MT, Isaacson KB, Lauffenburger DA, Griffith LG, Han J

Multiplexed protease activity assay for low-volume clinical samples using droplet-based microfluidics and its application to endometriosis. J Am Chem Soc. 2012;135(5):1645-8 - PMID: 23157326 - PMCID: PMC3566300 - DOI: 10.1021/ja307866z

Carlson J, Mikula H, Weissleder R

Unraveling tetrazine-triggered bioorthogonal elimination enables chemical tools for ultrafast release and universal cleavage. J Am Chem Soc. 2018;140(10):3603-3612 - PMID: 29384666 - PMCID: PMC5857921 - DOI: 10.1021/jacs.7b11217

Wilkovitsch M, Haider M, Sohr B, Herrmann B, Klubnick J, Weissleder R, Carlson JCT*, Mikula H*

A Cleavable C2-Symmetric trans-Cyclooctene Enables Fast and Complete Bioorthogonal Disassembly of Molecular Probes. J Am Chem Soc. 2020;142(45):19132-19141 - PMID: 33119297 - PMCID: PMC7662912 - DOI: 10.1021/jacs.0c07922

Syeda R, Holden MA, Hwang WL, Bayley H

Screening blockers against a potassium channel with a droplet interface bilayer array. J Am Chem Soc. 2008;130(46):15543-8 - PMID: 18950170 - DOI: 10.1021/ja804968g

Hwang WL, Chen M, Cronin B, Holden MA, Bayley H

Asymmetric droplet interface bilayers. J Am Chem Soc. 2008;130(18):5878-9 - PMID: 18407631 - DOI: 10.1021/ja802089s

Hwang WL, Holden MA, White S, Bayley H

Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling. J Am Chem Soc. 2007;129(38):11854-64 - PMID: 17764183 - DOI: 10.1021/ja074071a

Halabi EA, Weissleder R

Light-Deactivated Fluorescent Probes (FLASH-Off) for Multiplexed Imaging. J Am Chem Soc. 2023;:ePub - PMID: 37018018 - PMCID: PMC11853112 - DOI: 10.1021/jacs.3c00170

Hammel FA, Payne NC, Marando VM, Mazitschek R, Walker S

Identification of a Polypeptide Inhibitor of O-GlcNAc Transferase with Picomolar Affinity. J Am Chem Soc. 2024;146(38):26320-26330 - PMID: 39276112 - PMCID: PMC11440498 - DOI: 10.1021/jacs.4c08656

Kim HS, Simpson GG, Fei F, Garris C, Weissleder R

Fluorinated Ribonucleocarbohydrate Nanoparticles Allow Ultraefficient mRNA Delivery and Protein Expression in Tumor-Associated Myeloid Cells J Am Chem Soc. 2025;147(14):11766-11776 - PMID: 40135499 - PMCID: PMC11987029 - DOI: 10.1021/jacs.4c14474

Jeon J, Liu QJ, Woo H, Barth I, Choi Y, Sang LJ, Lee H

Computationally Designed Nanobinders as Affinity Ligands in Diagnostic and Therapeutic Applications. J Am Chem Soc. 2025;147(35):32187-32198 - PMID: 40839867 - DOI: 10.1021/jacs.5c11289

Zhu Q, Fischer G, Cheng SS, Payne NC, Peter D, Mody AC, Arce-Solano S, Shen D, Lin Z, Mazitschek R, Kessler D, Woo CM

Enzyme-Activated Sugar-Coated Bifunctional Degraders. J Am Chem Soc. 2025;147(38):34672-34680 - PMID: 40937862 - DOI: 10.1021/jacs.5c09843

Levy D, Moskowitz MA

Meningeal Mechanisms and the Migraine Connection. Annu Rev Neurosci. 2023;46:39-58 - PMID: 36913712 - PMCID: PMC11412714 - DOI: 10.1146/annurev-neuro-080422-105509

Yekula A, Minciacchi VR, Morello M, Shao H, Park Y, Zhang X, Muralidharan K, Freeman MR, Weissleder R, Lee H, Carter B, Breakefield XO, Di Vizio D, Balaj L

Large and small extracellular vesicles released by glioma cells in vitro and in vivo. J Extracell Vesicles. 2019;9(1):1689784 - PMID: 31839905 - PMCID: PMC6896449 - DOI: 10.1080/20013078.2019.1689784

Hsia T, Yekula A, Batool SM, Rosenfeld YB, You DG, Weissleder R, Lee H, Carter BS, Balaj L

Glioblastoma-derived extracellular vesicle subpopulations following 5-aminolevulinic acid treatment bear diagnostic implications. J Extracell Vesicles. 2022;11(11):e12278 - PMID: 36404434 - PMCID: PMC9676504 - DOI: 10.1002/jev2.12278

Welsh JA, Goberdhan DCI, O'Driscoll L, Buzas EI, Blenkiron C, Bussolati B, Cai H, Di Vizio D, Driedonks TAP, Erdbrügger U, Falcon-Perez JM, Fu QL, Hill AF, Lenassi M, Lim SK, Mahoney MG, Mohanty S, Möller A, Nieuwland R, Ochiya T, Sahoo S, Torrecilhas AC, Zheng L, Zijlstra A, Abuelreich S, Bagabas R, Bergese P, Bridges EM, Brucale M, Burger D, Carney RP, Cocucci E, Crescitelli R, Hanser E, Harris AL, Haughey NJ, Hendrix A, Ivanov AR, Jovanovic-Talisman T, Kruh-Garcia NA, Ku'ulei-Lyn Faustino V, Kyburz D, Lässer C, Lennon KM, Lötvall J, Maddox AL, Martens-Uzunova ES, Mizenko RR, Newman LA, Ridolfi A, Rohde E, Rojalin T, Rowland A, Saftics A, Sandau US, Saugstad JA, Shekari F, Swift S, Ter-Ovanesyan D, Tosar JP, Useckaite Z, Valle F, Varga Z, van der Pol E, van Herwijnen MJC, Wauben MHM, Wehman AM, Williams S, Zendrini A, Zimmerman AJ; MISEV Consortium; Théry C, Witwer KW

Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches J Extracell Vesicles. 2024;2:e12404 - PMID: 38326288 - PMCID: PMC10850029 - DOI: 10.1002/jev2.12404

Bae JH, Lee CH, Jung D, Yea K, Song BJ, Lee H, Baek MC

Extracellular vesicle isolation and counting system (EVics) based on simultaneous tandem tangential flow filtration and large field-of-view light scattering. J Extracell Vesicles. 2024;13(7):e12479 - PMID: 38978321 - PMCID: PMC11231039 - DOI: 10.1002/jev2.12479

Lee SY, Klingeborn M, Bulte JWM, Chiu DT, Chopp M, Cutler CW, Das S, Egwuagu CE, Fowler CD, Hamm-Alvarez SF, Lee H, Liu Y, Mead B, Moore TL, Ravindran S, Shetty AK, Skog J, Witwer KW, Djalilian AR, Weaver AM

A perspective from the National Eye Institute Extracellular Vesicle Workshop: Gaps, needs, and opportunities for studies of extracellular vesicles in vision research. J Extracell Vesicles. 2024;13(12):e70023 - PMID: 39665315 - PMCID: PMC11635481 - DOI: 10.1002/jev2.70023

Obuchi W, Zargani-Piccardi A, Leandro K, Rufino-Ramos D, Di Lanni E, Frederick DM, Maalouf K, Nieland L, Xiao T, Repiton P, Vaine CA, Kleinstiver BP, Bragg DC, Lee H, Miller MA, Breakefield XO, Breyne K

Engineering of CD63 Enables Selective Extracellular Vesicle Cargo Loading and Enhanced Payload Delivery. J Extracell Vesicles. 2025;14(6):e70094 - PMID: 40527733 - PMCID: PMC12173531 - DOI: 10.1002/jev2.70094

Stangenberg L, Ellson C, Cortez-Retamozo V, Ortiz-Lopez A, Yuan H, Blois J, Smith RA, Yaffe MB, Weissleder R, Benoist C, Mathis D, Josephson L, Mahmood U

Abrogation of antibody-induced arthritis in mice by a self-activating viridin prodrug and association with impaired neutrophil and endothelial cell function. Arthritis Rheumatol. 2009;60:2314-2324 - PMID: 19644878 - PMCID: PMC3080016 - DOI: 10.1002/art.24704

Stone JH, Khosroshahi A, Hilgenberg A, Spooner A, Isselbacher EM, Stone JR

IgG4-related systemic disease and lymphoplasmacytic aortitis. Arthritis Rheumatol. 2009;60(10):3139-3145 - PMID: 19790067 - DOI: 10.1002/art.24798

Wang H, Smith RN, Spooner AE, Isselbacher EM, Cambria RP, Macgillivray TE, Stone JH, Stone JR

Giant cell aortitis of the ascending aorta without signs or symptoms of systemic vasculitis is associated with elevated risk of distal aortic events. Arthritis Rheumatol. 2012;64(1):317-9 - PMID: 21953530 - DOI: 10.1002/art.33343

Stone JH, Khosroshahi A, Deshpande V, Chan JK, Heathcote JG, Aalberse R, Azumi A, Bloch DB, Brugge WR, Carruthers MN, Cheuk W, Cornell L, Castillo CF, Ferry JA, Forcione D, Klöppel G, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Masaki Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani D, Sato Y, Smyrk T, Stone JR, Takahira M, Umehara H, Webster G, Yamamoto M, Yi E, Yoshino T, Zamboni G, Zen Y, Chari S

IgG4-Related disease: recommendations for the nomenclature of this condition and its individual organ system manifestations. Arthritis Rheumatol. 2012;64(10):3061-7 - PMID: 22736240 - PMCID: PMC5963880 - DOI: 10.1002/art.34593

Patel NJ, Tozzo V, Higgins JM, Stone JH

The effects of daily prednisone and tocilizumab on hemoglobin A1c during the treatment of giant cell arteritis. Arthritis Rheumatol. 2022;75(4):586-594 - PMID: 36383175 - DOI: 10.1002/art.42405

Yu M, Riva L, Xie H, Schindler Y, Moran TB, Cheng Y, Yu D, Hardison R, Weiss MJ, Orkin SH, Bernstein BE, Fraenkel E, Cantor AB

Insights into GATA-1-Mediated Gene Activation versus Repression via Genome-wide Chromatin Occupancy Analysis. Mol Cell. 2009;36(4):682-95 - PMID: 19941827 - PMCID: PMC2800995 - DOI: 10.1016/j.molcel.2009.11.002

Garber M, Yosef N, Goren A, Raychowdhury R, Thielke A, Guttman M, Robinson J, Minie B, Chevrier N, Itzhaki Z, Blecher-Gonen R, Bornstein C, Amann-Zalcenstein D, Weiner A, Friedrich D, Meldrim J, Ram O, Cheng C, Gnirke A, Fisher S, Friedman N, Wong B, Bernstein BE, Nusbaum C, Hacohen N, Regev A, Amit I

A High-Throughput Chromatin Immunoprecipitation Approach Reveals Principles of Dynamic Gene Regulation in Mammals. Mol Cell. 2012;47(5):810-22 - PMID: 22940246 - PMCID: PMC3873101 - DOI: 10.1016/j.molcel.2012.07.030

van Galen P, Viny AD, Ram O, Ryan RJ, Cotton MJ, Donohue L, Sievers C, Drier Y, Liau BB, Gillespie SM, Carroll KM, Cross MB, Levine RL, Bernstein BE

A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes. Mol Cell. 2015;61(1):170-80 - PMID: 26687680 - PMCID: PMC4707994 - DOI: 10.1016/j.molcel.2015.11.003

Harisinghani MG, Weissleder R

Sensitive, noninvasive detection of lymph node metastases. PLoS Med. 2004;1(3):e66 - PMID: 15630471 - PMCID: PMC539052 - DOI: 10.1371/journal.pmed.0010066

Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R

Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma. PLoS Med. 2008;5(4):e85 - PMID: 18416599 - PMCID: PMC2292750 - DOI: 10.1371/journal.pmed.0050085

Leming MJ, Bron EE, Bruffaerts R, Ou Y, Iglesias JE, Gollub RL, Im H

Challenges of implementing computer-aided diagnostic models for neuroimages in a clinical setting. NPJ Digit Med. 2023;6(1):129 - PMID: 37443276 - PMCID: PMC10345121 - DOI: 10.1038/s41746-023-00868-x

Peterson HM, Chin LK, Iwamoto Y, Oh J, Carlson JCT, Lee H, Im H, Weissleder R

Integrated Analytical System for Clinical Single-Cell Analysis Adv Sci (Weinh). 2022;9(20):e2200415 - PMID: 35508767 - PMCID: PMC9284190 - DOI: 10.1002/advs.202200415

Kim H, Sa JK, Kim J, Cho HJ, Oh HJ, Choi DH, Kang SH, Jeong DE, Nam DH, Lee H, Lee HW, Chung S

Recapitulated Crosstalk between Cerebral Metastatic Lung Cancer Cells and Brain Perivascular Tumor Microenvironment in a Microfluidic Co-Culture Chip. Adv Sci (Weinh). 2022;9(22):e2201785 - PMID: 35657027 - PMCID: PMC9353479 - DOI: 10.1002/advs.202201785

Ko J, Lucas K, Kohler RH, Halabi EA, Wilkovitsch M, Carlson JCT, Weissleder R

In Vivo Click Chemistry Enables Multiplexed Intravital Microscopy Adv Sci (Weinh). 2022;9(24):e2200064 - PMID: 35750648 - PMCID: PMC9405492 - DOI: 10.1002/advs.202200064

Jeong MH, Son T, Tae YK, Park CH, Lee HS, Chung MJ, Park JY, Castro CM, Weissleder R, Jo JH, Bang S, Im H

Plasmon-Enhanced Single Extracellular Vesicle Analysis for Cholangiocarcinoma Diagnosis. Adv Sci (Weinh). 2023;10(8):e2205148 - PMID: 36698298 - PMCID: PMC10015870 - DOI: 10.1002/advs.202205148

Roh YH, Lee CY, Lee S, Kim H, Ly A, Castro CM, Cheon J, Lee JH, Lee H

CRISPR-Enhanced Hydrogel Microparticles for Multiplexed Detection of Nucleic Acids. Adv Sci (Weinh). 2023;10(10):e2206872 - PMID: 36725305 - PMCID: PMC10074104 - DOI: 10.1002/advs.202206872

Hong JS, Son T, Castro CM, Im H

CRISPR/Cas13a-Based MicroRNA Detection in Tumor-Derived Extracellular Vesicles. Adv Sci (Weinh). 2023;10(24):e2301766 - PMID: 37340600 - PMCID: PMC10460892 - DOI: 10.1002/advs.202301766

Jo A, Green A, Medina JE, Iyer S, Ohman AW, McCarthy ET, Reinhardt F, Gerton T, Demehin D, Mishra R, Kolin DL, Zheng H, Cheon J, Crum CP, Weinberg RA, Rueda BR, Castro CM, Dinulescu DM, Lee H

Inaugurating High-Throughput Profiling of Extracellular Vesicles for Earlier Ovarian Cancer Detection. Adv Sci (Weinh). 2023;10(27):e2301930 - PMID: 37485618 - PMCID: PMC10520636 - DOI: 10.1002/advs.202301930

Das R*, Halabi EA*, Fredrich IR, Oh J, Peterson HM, Ge X, Scott E, Kohler RH, Garris CS, Weissleder R

Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery. Adv Sci (Weinh). 2023;10(33):e2303576 - PMID: 37814359 - PMCID: PMC10667837 - DOI: 10.1002/advs.202303576

Korolj A, Kohler RH, Scott E, Halabi EA, Lucas K, Carlson JCT, Weissleder R

Perfusion Window Chambers Enable Interventional Analyses of Tumor Microenvironments. Adv Sci (Weinh). 2023;10(34):e2304886 - PMID: 37870204 - PMCID: PMC10700240 - DOI: 10.1002/advs.202304886

Reynolds DE, Sun Y, Wang X, Vallapureddy P, Lim J, Pan M, Fernandez Del Castillo A, Carlson JCT, Sellmyer MA, Nasrallah M, Binder Z, O'Rourke DM, Ming GL, Song H, Ko J

Live Organoid Cyclic Imaging. Adv Sci (Weinh). 2024;11(14):e2309289 - PMID: 38326078 - PMCID: PMC11005682 - DOI: 10.1002/advs.202309289

Enbergs N*, Halabi EA*, Goubet AG, Schleyer K, Fredrich IR, Kohler RH, Garris CS, Pittet MJ, Weissleder R

Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype. Adv Sci (Weinh). 2024;11(15):e2309026 - PMID: 38342608 - PMCID: PMC11022742 - DOI: 10.1002/advs.202309026

Kartal B, Garris CS, Kim HS, Kohler RH, Carrothers J, Halabi EA, Iwamoto Y, Goubet AG, Xie Y, Wirapati P, Pittet MJ, Weissleder R

Targeted SPP1 Inhibition of Tumor-Associated Myeloid Cells Effectively Decreases Tumor Sizes. Adv Sci (Weinh). 2024;12(4):e2410360 - PMID: 39639496 - PMCID: PMC11775521 - DOI: 10.1002/advs.202410360

Condeelis J, Weissleder R

In Vivo Imaging in Cancer. Cold Spring Harb Perspect Biol. 2010;2(12):a003848 - PMID: 20861158 - PMCID: PMC2982169 - DOI: 10.1101/cshperspect.a003848

Leming M, Kim K, Bruffaerts R, Im H

Strategies for mitigating data heterogeneities in AI-based neuro-disease detection. Neuron. 2025;113(8):1129-1132 - PMID: 40037359 - DOI: 10.1016/j.neuron.2025.01.028

Jones G, Anderson JL, Nguyen PTT, Gleber-Netto FO, Hwang WL, Puduvalli VK, Monje M, Amit M

Novel approaches to clinical trial design in cancer neuroscience. Neuron. 2025;113(17):2791-2813 - PMID: 40907474 - PMCID: PMC12435926 - DOI: 10.1016/j.neuron.2025.08.015

Ashida N, Senbanerjee S, Kodama S, Foo SY, Coggins M, Spencer JA, Zamiri P, Shen D, Li L, Sciuto T, Dvorak A, Gerszten RE, Lin CP, Karin M, Rosenzweig A

IKKb regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways. Nat Commun. 2011;2:318 - PMID: 21587235 - PMCID: PMC3113230 - DOI: 10.1038/ncomms1317

Shi P, Scott MA, Ghosh B, Wan D, Wissner-Gross Z, Mazitschek R, Haggarty SJ, Yanik MF

Synapse microarray identification of small molecules that enhance synaptogenesis. Nat Commun. 2011;2:510 - PMID: 22027590 - PMCID: PMC3544154 - DOI: 10.1038/ncomms1518

Lee S, Vinegoni C, Feruglio PF, Fexon L, Gorbatov R, Pivovarov M, Sbarbati A, Nahrendorf M, Weissleder R

Real-time in vivo imaging of the beating mouse heart at microscopic resolution Nat Commun. 2012;3:1054 - PMID: 22968700 - PMCID: PMC3622400 - DOI: 10.1038/ncomms2060

Thurber GM, Yang KS, Reiner T, Kohler RH, Sorger P, Mitchison T, Weissleder R

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo. Nat Commun. 2013;4:1504 - PMID: 23422672 - PMCID: PMC3579506 - DOI: 10.1038/ncomms2506

Liong M, Hoang AN, Chung J, Gural N, Ford CB, Min C, Shah RR, Ahmad R, Fernandez-Suarez M, Fortune SM, Toner M, Lee H*, Weissleder R*

Magnetic barcode assay for genetic detection of pathogens Nat Commun. 2013;4:1752 - PMID: 23612293 - PMCID: PMC3635151 - DOI: 10.1038/ncomms2745

Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW

Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nat Commun. 2013;4:2189 - PMID: 23877263 - PMCID: PMC3740589 - DOI: 10.1038/ncomms3189

Ageta-Ishihara N, Miyata T, Ohshima C, Watanabe M, Sato Y, Hamamura Y, Higashiyama T, Mazitschek R, Bito H, Kinoshita M

Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation. Nat Commun. 2013;4:2532 - PMID: 24113571 - PMCID: PMC3826633 - DOI: 10.1038/ncomms3532

Duivenvoorden R, Tang J, Cormode DP, Mieszawska AJ, Izquierdo-Garcia D, Ozcan C, Otten MJ, Zaidi N, Lobatto ME, van Rijs SM, Priem B, Kuan EL, Martel C, Hewing B, Sager H, Nahrendorf M, Randolph GJ, Stroes ES, Fuster V, Fisher EA, Fayad ZA, Mulder WJ

A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation. Nat Commun. 2014;5:3065 - PMID: 24445279 - PMCID: PMC4001802 - DOI: 10.1038/ncomms4065

Dubach JM, Vinegoni C, Mazitschek R, Fumene Feruglio P, Cameron LA, Weissleder R

In vivo imaging of specific drug-target binding at subcellular resolution. Nat Commun. 2014;5:3946 - PMID: 24867710 - PMCID: PMC4362617 - DOI: 10.1038/ncomms4946

Lee SK, Mortensen LJ, Lin CP, Tung CH

An authentic imaging probe to track cell fate from beginning to end. Nat Commun. 2014;5:5216 - PMID: 25323442 - PMCID: PMC4852472 - DOI: 10.1038/ncomms6216

Shen K, Luk S, Hicks DF, Elman JS, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush ML, Toner M, Sgroi D, Parekkadan B

Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays. Nat Commun. 2014;5:5662 - PMID: 25489927 - PMCID: PMC4261930 - DOI: 10.1038/ncomms6662

Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, Hochberg FH, Breakefield XO, Lee H*, Weissleder R*

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma Nat Commun. 2015;6:6999 - PMID: 25959588 - PMCID: PMC4430127 - DOI: 10.1038/ncomms7999

Lai CP, Kim EY, Badr CE, Weissleder R, Mempel TR, Tannous BA, Breakefield XO

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters. Nat Commun. 2015;6:7029 - PMID: 25967391 - PMCID: PMC4435621 - DOI: 10.1038/ncomms8029

Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R

Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nat Commun. 2015;6:8692 - PMID: 26503691 - PMCID: PMC4711745 - DOI: 10.1038/ncomms9692

Signore S, Sorrentino A, Borghetti G, Cannata A, Meo M, Zhou Y, Kannappan R, Pasqualini F, O'Malley H, Sundman M, Tsigkas N, Zhang E, Arranto C, Mangiaracina C, Isobe K, Sena BF, Kim J, Goichberg P, Nahrendorf M, Isom LL, Leri A, Anversa P, Rota M

Late Na(+) current and protracted electrical recovery are critical determinants of the aging myopathy. Nat Commun. 2015;6:8803 - PMID: 26541940 - PMCID: PMC4638135 - DOI: 10.1038/ncomms9803

Roy J*, Kim B*, Hill E, Visconti P, Krapf D, Vinegoni C, Weissleder R, Brown D, Breton S

Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging. Nat Commun. 2016;7:10666 - PMID: 26868824 - PMCID: PMC4754344 - DOI: 10.1038/ncomms10666

Vinegoni C, Leon Swisher C, Fumene Feruglio P, Giedt RJ, Rousso DL, Stapleton S, Weissleder R

Real-time high dynamic range laser scanning microscopy. Nat Commun. 2016;7:11077 - PMID: 27032979 - PMCID: PMC4821995 - DOI: 10.1038/ncomms11077

Aryal B, Rotllan N, Araldi E, Ramírez CM, He S, Chousterman BG, Fenn AM, Wanschel A, Madrigal-Matute J, Warrier N, Martín-Ventura JL, Swirski FK, Suárez Y, Fernández-Hernando C

ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 - PMID: 27460411 - PMCID: PMC4974469 - DOI: 10.1038/ncomms12313

Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M

Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease. Nat Commun. 2017;8:14064 - PMID: 28091604 - PMCID: PMC5241815 - DOI: 10.1038/ncomms14064

Cuccarese MF, Dubach JM, Pfirschke C, Engblom C, Garris C, Miller MA, Pittet MJ, Weissleder R

Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3D organ imaging. Nat Commun. 2017;8:14293 - PMID: 28176769 - PMCID: PMC5309815 - DOI: 10.1038/ncomms14293

Schlomann U, Koller G, Conrad C, Ferdous T, Golfi P, Garcia AM, Höfling S, Parsons M, Costa P, Soper R, Bossard M, Hagemann T, Roshani R, Sewald N, Ketchem RR, Moss ML, Rasmussen FH, Miller MA, Lauffenburger DA, Tuveson DA, Nimsky C, Bartsch JW

ADAM8 as a drug target in pancreatic cancer. Nat Commun. 2015;6:6175 - PMID: 25629724 - PMCID: PMC5014123 - DOI: 10.1038/ncomms7175

Walsh RM, Shen EY, Bagot RC, Anselmo A, Jiang Y, Javidfar B, Wojtkiewicz GJ, Cloutier J, Chen JW, Sadreyev R, Nestler EJ, Akbarian S, Hochedlinger K

Phf8 loss confers resistance to depression-like and anxiety-like behaviors in mice. Nat Commun. 2017;8:15142 - PMID: 28485378 - PMCID: PMC5436068 - DOI: 10.1038/ncomms15142

Chen X, Park HR, Pelton M, Piao X, Lindquist NC, Im H, Kim YJ, Ahn JS, Ahn KJ, Park N, Kim DS, Oh SH

Atomic layer lithography of wafer-scale nanogap arrays for extreme confinement of electromagnetic waves. Nat Commun. 2013;4:2361 - PMID: 23999053 - DOI: 10.1038/ncomms3361

Miller MA, Askevold B, Mikula H, Kohler RH, Pirovich D, Weissleder R

Nano-palladium is a cellular catalyst for in vivo chemistry Nat Commun. 2017;8:15906 - PMID: 28699627 - PMCID: PMC5510178 - DOI: 10.1038/ncomms15906

Ingram JR, Dougan M, Rashidian M, Knoll M, Keliher EJ, Garrett S, Garforth S, Blomberg OS, Espinosa C, Bhan A, Almo SC, Weissleder R, Lodish H, Dougan SK, Ploegh HL

PD-L1 is an activation-independent marker of brown adipocytes. Nat Commun. 2017;8(1):647 - PMID: 28935898 - PMCID: PMC5608754 - DOI: 10.1038/s41467-017-00799-8

Kitano K, Schwartz DM, Zhou H, Gilpin SE, Wojtkiewicz GR, Ren X, Sommer CA, Capilla AV, Mathisen DJ, Goldstein AM, Mostoslavsky G, Ott HC

Bioengineering of functional human induced pluripotent stem cell-derived intestinal grafts. Nat Commun. 2017;8(1):765 - PMID: 29018244 - PMCID: PMC5635127 - DOI: 10.1038/s41467-017-00779-y

Shao L, Chang J, Feng W, Wang X, Williamson EA, Li Y, Schajnovitz A, Scadden D, Mortensen LJ, Lin CP, Li L, Paulson A, Downing J, Zhou D, Hromas RA

The Wave2 scaffold Hem-1 is required for transition of fetal liver hematopoiesis to bone marrow. Nat Commun. 2018;9(1):2377 - PMID: 29915352 - PMCID: PMC6006146 - DOI: 10.1038/s41467-018-04716-5

Karaayvaz M, Cristea S, Gillespie SM, Patel AP, Mylvaganam R, Luo CC, Specht MC, Bernstein BE, Michor F, Ellisen LW

Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq. Nat Commun. 2018;9(1):3588 - PMID: 30181541 - PMCID: PMC6123496 - DOI: 10.1038/s41467-018-06052-0

Giedt RJ, Pathania D, Carlson JCT, McFarland PJ, Del Castillo AF, Juric D, Weissleder R

Single-cell barcode analysis provides a rapid readout of cellular signaling pathways in clinical specimens Nat Commun. 2018;9(1):4550 - PMID: 30382095 - PMCID: PMC6208406 - DOI: 10.1038/s41467-018-07002-6

Liu P, Zhao L, Pol J, Levesque S, Petrazzuolo A, Pfirschke C, Engblom C, Rickelt S, Yamazaki T, Iribarren K, Senovilla L, Bezu L, Vacchelli E, Sica V, Melis A, Martin T, Xia L, Yang H, Li Q, Chen J, Durand S, Aprahamian F, Lefevre D, Broutin S, Paci A, Bongers A, Minard-Colin V, Tartour E, Zitvogel L, Apetoh L, Ma Y, Pittet MJ, Kepp O, Kroemer G

Crizotinib-induced immunogenic cell death in non-small cell lung cancer. Nat Commun. 2019;10(1):1486 - PMID: 30940805 - PMCID: PMC6445096 - DOI: 10.1038/s41467-019-09415-3

Pastore A, Gaiti F, Lu SX, Brand RM, Kulm S, Chaligne R, Gu H, Huang KY, Stamenova EK, Béguelin W, Jiang Y, Schulman RC, Kim KT, Alonso A, Allan JN, Furman RR, Gnirke A, Wu CJ, Melnick AM, Meissner A, Bernstein BE, Abdel-Wahab O, Landau DA

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL. Nat Commun. 2019;10(1):1874 - PMID: 31015400 - PMCID: PMC6478836 - DOI: 10.1038/s41467-019-09645-5

Liu CL, Zhang X, Liu J, Wang Y, Sukhova GK, Wojtkiewicz GR, Liu T, Tang R, Achilefu S, Nahrendorf M, Libby P, Guo J, Zhang JY, Shi GP

Na+ - H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis. Nat Commun. 2019;10(1):3978 - PMID: 31484936 - PMCID: PMC6726618 - DOI: 10.1038/s41467-019-11983-3

Tarjan DR, Flavahan WA, Bernstein BE

Epigenome editing strategies for the functional annotation of CTCF insulators. Nat Commun. 2019;10(1):4258 - PMID: 31534142 - PMCID: PMC6751197 - DOI: 10.1038/s41467-019-12166-w

Cabal-Hierro L, van Galen P, Prado MA, Higby KJ, Togami K, Mowery CT, Paulo JA, Xie Y, Cejas P, Furusawa T, Bustin M, Long HW, Sykes DB, Gygi SP, Finley D, Bernstein BE, Lane AA

Chromatin accessibility promotes hematopoietic and leukemia stem cell activity. Nat Commun. 2020;11(1):1406 - PMID: 32179749 - PMCID: PMC7076002 - DOI: 10.1038/s41467-020-15221-z

Boivin G, Faget J, Ancey PB, Gkasti A, Mussard J, Engblom C, Pfirschke C, Contat C, Pascual J, Vazquez J, Bendriss-Vermare N, Caux C, Vozenin MC, Pittet MJ, Gunzer M, Meylan E

Durable and controlled depletion of neutrophils in mice. Nat Commun. 2020;11(1):2762 - PMID: 32488020 - PMCID: PMC7265525 - DOI: 10.1038/s41467-020-16596-9

Luthria G, Li R, Wang S, Prytyskach M, Kohler RH, Lauffenburger DA, Mitchison TJ, Weissleder R, Miller MA

In vivo microscopy reveals macrophage polarization locally promotes coherent microtubule dynamics in migrating cancer cells Nat Commun. 2020;11:3521 - PMID: 32665556 - PMCID: PMC7360550 - DOI: 10.1038/s41467-020-17147-y

Javed N, Farjoun Y, Fennell TJ, Epstein CB, Bernstein BE, Shoresh N

Detecting sample swaps in diverse NGS data types using linkage disequilibrium. Nat Commun. 2020;11(1):3697 - PMID: 32728101 - PMCID: PMC7391710 - DOI: 10.1038/s41467-020-17453-5

Oki T, Mercier F, Kato H, Jung Y, McDonald TO, Spencer JA, Mazzola MC, van Gastel N, Lin CP, Michor F, Kitamura T, Scadden DT

Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML. Nat Commun. 2021;12(1):245 - PMID: 33431855 - PMCID: PMC7801403 - DOI: 10.1038/s41467-020-20491-8

Stewart-Ornstein J, Iwamoto Y, Miller MA, Prytyskach MA, Ferretti S, Holzer P, Kallen J, Furet P, Jambhekar A, Forrester WC, Weissleder R, Lahav G

p53 dynamics vary between tissues and are linked with radiation sensitivity Nat Commun. 2021;12(1):898 - PMID: 33563973 - PMCID: PMC7873198 - DOI: 10.1038/s41467-021-21145-z

Bénard A, Jacobsen A, Brunner M, Krautz C, Klösch B, Swierzy I, Naschberger E, Podolska MJ, Kouhestani D, David P, Birkholz T, Castellanos I, Trufa D, Sirbu H, Vetter M, Kremer AE, Hildner K, Hecker A, Edinger F, Tenbusch M, Mühl-Zürbes P, Steinkasserer A, Richter E, Streeck H, Berger MM, Brenner T, Weigand MA, Swirski FK, Schett G, Grützmann R, Weber GF

Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections. Nat Commun. 2021;12(1):1112 - PMID: 33602937 - PMCID: PMC7893044 - DOI: 10.1038/s41467-021-21310-4

Wang JS, Kamath T, Mazur CM, Mirzamohammadi F, Rotter D, Hojo H, Castro CD, Tokavanich N, Patel R, Govea N, Enishi T, Wu Y, da Silva Martins J, Bruce M, Brooks DJ, Bouxsein ML, Tokarz D, Lin CP, Abdul A, Macosko EZ, Fiscaletti M, Munns CF, Ryder P, Kost-Alimova M, Byrne P, Cimini B, Fujiwara M, Kronenberg HM, Wein MN

Control of osteocyte dendrite formation by Sp7 and its target gene osteocrin. Nat Commun. 2021;12(1):6271 - PMID: 34725346 - PMCID: PMC8560803 - DOI: 10.1038/s41467-021-26571-7

Yeh SA, Hou J, Wu JW, Yu S, Zhang Y, Belfield KD, Camargo FD, Lin CP

Quantification of bone marrow interstitial pH and calcium concentration by intravital ratiometric imaging. Nat Commun. 2022;13(1):393 - PMID: 35046411 - PMCID: PMC8770570 - DOI: 10.1038/s41467-022-27973-x

Foy BH, Sundt TM, Carlson JCT, Aguirre AD, Higgins JM

Human acute inflammatory recovery is defined by co-regulatory dynamics of white blood cell and platelet populations. Nat Commun. 2022;13(1):4705 - PMID: 35995789 - PMCID: PMC9395541 - DOI: 10.1038/s41467-022-32222-2

Tye MA, Payne NC, Johansson C, Singh K, Santos SA, Fagbami L, Pant A, Sylvester K, Luth MR, Marques S, Whitman M, Mota MM, Winzeler EA, Lukens AK, Derbyshire ER, Oppermann U, Wirth DF, Mazitschek R

Elucidating the path to Plasmodium prolyl-tRNA synthetase inhibitors that overcome halofuginone resistance. Nat Commun. 2022;13(1):4976 - PMID: 36008486 - PMCID: PMC9403976 - DOI: 10.1038/s41467-022-32630-4

Che M, Chaturvedi A, Munro SA, Pitzen SP, Ling A, Zhang W, Mentzer J, Ku SY, Puca L, Zhu Y, Bergman AM, Severson TM, Forster C, Liu Y, Hildebrand J, Daniel M, Wang TY, Selth LA, Hickey T, Zoubeidi A, Gleave M, Bareja R, Sboner A, Tilley W, Carroll JS, Tan W, Kohli M, Yang R, Hsieh AC, Murugan P, Zwart W, Beltran H, Huang RS, Dehm SM

Opposing transcriptional programs of KLF5 and AR emerge during therapy for advanced prostate cancer. Nat Commun. 2021;12(1):6377 - PMID: 34737261 - PMCID: PMC8568894 - DOI: 10.1038/s41467-021-26612-1

Momin N, Palmeri JR, Lutz EA, Jailkhani N, Mak H, Tabet A, Chinn MM, Kang BH, Spanoudaki V, Hynes RO, Wittrup KD

Maximizing response to intratumoral immunotherapy in mice by tuning local retention. Nat Commun. 2022;13(1):109 - PMID: 35013154 - PMCID: PMC8748612 - DOI: 10.1038/s41467-021-27390-6

Turco V, Pfleiderer K, Hunger J, Horvat NK, Karimian-Jazi K, Schregel K, Fischer M, Brugnara G, Jähne K, Sturm V, Streibel Y, Nguyen D, Altamura S, Agardy DA, Soni SS, Alsasa A, Bunse T, Schlesner M, Muckenthaler MU, Weissleder R, Wick W, Heiland S, Vollmuth P, Bendszus M, Rodell CB, Breckwoldt MO, Platten M

T cell-independent eradication of experimental glioma by intravenous TLR7/8-agonist-loaded nanoparticles. Nat Commun. 2023;14(1):771 - PMID: 36774352 - PMCID: PMC9922247 - DOI: 10.1038/s41467-023-36321-6

Spitzberg JD, Ferguson S, Yang KS, Peterson HM, Carlson JCT, Weissleder R

Multiplexed analysis of EV reveals specific biomarker composition with diagnostic impact. Nat Commun. 2023;14(1):1239 - PMID: 36870999 - PMCID: PMC9985597 - DOI: 10.1038/s41467-023-36932-z

De Souza DC, Hebert N, Esrick EB, Ciuculescu MF, Archer NM, Armant M, Audureau, Brendel C, Di Caprio G, Galactéros F, Liu D, McCabe A, Morris E, Schonbrun E, Williams D, Wood DK, Williams DA, Bartolucci P, Higgins JM

Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling. Nat Commun. 2023;14(1):5850 - PMID: 37730674 - PMCID: PMC10511721 - DOI: 10.1038/s41467-023-40923-5

Stollmann A, Garcia-Guirado J, Hong JS, Rüedi P, Im H, Lee H, Ortega Arroyo J, Quidant R

Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform. Nat Commun. 2024;15(1):4109 - PMID: 38750038 - PMCID: PMC11096335 - DOI: 10.1038/s41467-024-48132-4

Diez I, Ortiz-Terán L, Ng TSC, Albers MW, Marshall G, Orwig W, Kim CM, Bueichekú E, Montal V, Olofsson J, Vannini P, El Fahkri G, Sperling R, Johnson K, Jacobs HIL, Sepulcre J

Tau propagation in the brain olfactory circuits is associated with smell perception changes in aging. Nat Commun. 2024;15(1):4809 - PMID: 38844444 - PMCID: PMC11156945 - DOI: 10.1038/s41467-024-48462-3

Lee CY, Kim H, Degani I, Lee H, Sandoval A, Nam Y, Pascavis M, Park HG, Randall T, Ly A, Castro CM, Lee H

Empowering the on-site detection of nucleic acids by integrating CRISPR and digital signal processing. Nat Commun. 2024;15(1):6271 - PMID: 39054353 - PMCID: PMC11272939 - DOI: 10.1038/s41467-024-50588-3

Foy BH, Carlson JCT, Aguirre AD, Higgins JM

Platelet-white cell ratio is more strongly associated with mortality than other common risk ratios derived from complete blood counts. Nat Commun. 2025;16(1):1113 - PMID: 39875373 - PMCID: PMC11775293 - DOI: 10.1038/s41467-025-56251-9

Chung JY, Hong YK, Jeon E, Yang S, Park A, Weissleder R, Chong YP, Chung HJ

Effective treatment of systemic candidiasis by synergistic targeting of cell wall synthesis. Nat Commun. 2025;16(1):5532 - PMID: 40595501 - PMCID: PMC12215473 - DOI: 10.1038/s41467-025-60684-7

Ozsolak F, Goren A, Gymrek MA, Guttman M, Regev A, Bernstein BE, Milos PM

Digital transcriptome profiling from attomole-level RNA samples. Genome Res. 2010;20(4):519-25 - PMID: 20133332 - PMCID: PMC2847755 - DOI: 10.1101/gr.102129.109

Landt SG, Marinov GK, Kundaje A, Kheradpour P, Pauli F, Batzoglou S, Bernstein BE, Bickel P, Brown JB, Cayting P, Chen Y, Desalvo G, Epstein C, Fisher-Aylor KI, Euskirchen G, Gerstein M, Gertz J, Hartemink AJ, Hoffman MM, Iyer VR, Jung YL, Karmakar S, Kellis M, Kharchenko PV, Li Q, Liu T, Liu XS, Ma L, Milosavljevic A, Myers RM, Park PJ, Pazin MJ, Perry MD, Raha D, Reddy TE, Rozowsky J, Shoresh N, Sidow A, Slattery M, Stamatoyannopoulos JA, Tolstorukov MY, White KP, Xi S, Farnham PJ, Lieb JD, Wold BJ, Snyder M

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia. Genome Res. 2012;22(9):1813-31 - PMID: 22955991 - PMCID: PMC3431496 - DOI: 10.1101/gr.136184.111

Attanasio C, Nord AS, Zhu Y, Blow MJ, Biddie SC, Mendenhall EM, Dixon J, Wright CA, Hosseini R, Akiyama JA, Holt A, Plajzer-Frick I, Shoukry M, Afzal V, Ren B, Bernstein B, Rubin E, Visel A, Pennacchio L

Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis. Genome Res. 2014;24(6):920-9 - PMID: 24752179 - PMCID: PMC4032856 - DOI: 10.1101/gr.168930.113

Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC

Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006;203(1):141-152 - PMID: 16390934 - PMCID: PMC2118091 - DOI: 10.1084/jem.20050390

Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D.

Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk J Exp Med. 2007;204:1911-1922 - PMID: 17646407 - PMCID: PMC2118664 - DOI: 10.1084/jem.20070285

Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo JL, Libby P, Weissleder R, Pittet MJ

The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204(12):3037-47 - PMID: 18025128 - PMCID: PMC2118517 - DOI: 10.1084/jem.20070885

Zippelius A, Pittet M, Batard P, Rufer N, de Smedt M, Guillaume P, Ellefsen K, Valmori D, Lienard D, Plum J, MacDonald H, Speiser D, Cerottini J, Romero P

Thymic selection generates a large T cell pool recognizing a self-peptide in humans. J Exp Med. 2002;195:485-94 - PMID: 11854361 - PMCID: PMC2193620 - DOI: 10.1084/jem.20011658

Dutoit V, Rubio-Godoy V, Pittet M, Zippelius A, Dietrich P, Legal F, Guillaume P, Romero P, Cerottini J, Houghten R, Pinilla C, Valmori D

Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans. J Exp Med. 2002;196:207-16 - PMID: 12119345 - PMCID: PMC2193921 - DOI: 10.1084/jem.20020242

Romero P, Dunbar P, Valmori D, Pittet M, Ogg G, Rimoldi D, Chen J, Lienard D, Cerottini J, Cerundolo V

Ex vivo staining of metastatic lymph nodes by class I major histocompatibility complex tetramers reveals high numbers of antigen-experienced tumor-specific cytolytic T lymphocytes. J Exp Med. 1998;188:1641-50 - PMID: 9802976 - PMCID: PMC2212507 - DOI: 10.1084/jem.188.9.1641

Speiser D, Pittet M, Valmori D, Dunbar R, Rimoldi D, Lienard D, MacDonald H, Cerottini J, Cerundolo V, Romero P

In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes. J Exp Med. 1999;190:775-82 - PMID: 10499916 - PMCID: PMC2195637 - DOI: 10.1084/jem.190.6.775

Pittet M, Valmori D, Dunbar P, Speiser D, Lienard D, Lejeune F, Fleischhauer K, Cerundolo V, Cerottini J, Romero P

High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals. J Exp Med. 1999;190:705-15 - PMID: 10477554 - PMCID: PMC2195613 - DOI: 10.1084/jem.190.5.705

Chakraverty R, Cote D, Buchli J, Cotter P, Hsu R, Zhao G, Sachs T, Pitsillides C, Bronson R, Means T, Lin CP, Sykes M

An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. J Exp Med. 2006;203:2021-31 - PMID: 16880259 - PMCID: PMC2118376 - DOI: 10.1084/jem.20060376

Leuschner F, Rauch PJ, Ueno T, Gorbatov R, Marinelli B, Lee WW, Dutta P, Wei Y, Robbins C, Iwamoto Y, Sena B, Chudnovskiy A, Panizzi P, Keliher E, Higgins JM, Libby P, Moskowitz MA, Pittet MJ, Swirski FK, Weissleder R, Nahrendorf M

Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis. J Exp Med. 2012;209(1):123-37 - PMID: 22213805 - PMCID: PMC3260875 - DOI: 10.1084/jem.20111009

Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, Pandey S, Shin JY, Telis L, Liu J, Bhatt PK, Monette S, Zhao X, Mason CE, Park CY, Bernstein BE, Aifantis I, Levine RL

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo. J Exp Med. 2013;210(12):2641-59 - PMID: 24218140 - PMCID: PMC3832937 - DOI: 10.1084/jem.20131141

Weber GF, Chousterman BG, Hilgendorf I, Robbins CS, Theurl I, Gerhardt LM, Iwamoto Y, Quach TD, Ali M, Chen JW, Rothstein TL, Nahrendorf M, Weissleder R, Swirski FK

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis. J Exp Med. 2014;211(6):1243-56 - PMID: 24821911 - PMCID: PMC4042649 - DOI: 10.1084/jem.20131471

Dutta P, Hoyer FF, Grigoryeva LS, Sager HB, Leuschner F, Courties G, Borodovsky A, Novobrantseva T, Ruda VM, Fitzgerald K, Iwamoto Y, Wojtkiewicz G, Sun Y, Da Silva N, Libby P, Anderson DG, Swirski FK, Weissleder R, Nahrendorf M

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1. J Exp Med. 2015;212(4):497-512 - PMID: 25800955 - PMCID: PMC4387283 - DOI: 10.1084/jem.20141642

Anzai A, Choi JL, He S, Fenn AM, Nairz M, Rattik S, McAlpine CS, Mindur JE, Chan CT, Iwamoto Y, Tricot B, Wojtkiewicz GR, Weissleder R, Libby P, Nahrendorf M, Stone JR, Becher B, Swirski FK

The infarcted myocardium solicits GM-CSF for the detrimental oversupply of inflammatory leukocytes. J Exp Med. 2017;214(11):3293-3310 - PMID: 28978634 - PMCID: PMC5679174 - DOI: 10.1084/jem.20170689

Hulsmans M, Sager HB, Roh JD, Valero-Muñoz M, Houstis NE, Iwamoto Y, Sun Y, Wilson RM, Wojtkiewicz G, Tricot B, Osborne MT, Hung J, Vinegoni C, Naxerova K, Sosnovik DE, Zile MR, Bradshaw AD, Liao R, Tawakol A, Weissleder R, Rosenzweig A, Swirski FK, Sam F, Nahrendorf M

Cardiac macrophages promote diastolic dysfunction. J Exp Med. 2018;215(2):423-440 - PMID: 29339450 - PMCID: PMC5789416 - DOI: 10.1084/jem.20171274

Anzai A, Mindur JE, Halle L, Sano S, Choi JL, He S, McAlpine CS, Chan CT, Kahles F, Valet C, Fenn AM, Nairz M, Rattik S, Iwamoto Y, Fairweather D, Walsh K, Libby P, Nahrendorf M, Swirski FK

Self-reactive CD4+ IL-3+ T cells amplify autoimmune inflammation in myocarditis by inciting monocyte chemotaxis. J Exp Med. 2019;216(2):369-383 - PMID: 30670465 - PMCID: PMC6363430 - DOI: 10.1084/jem.20180722

Chan CT, Fenn AM, Harder NK, Mindur JE, McAlpine CS, Patel J, Valet C, Rattik S, Iwamoto Y, He S, Anzai A, Kahles F, Poller WC, Janssen H, Wong LP, Fernandez-Hernando C, Koolbergen DR, van der Laan AM, Yvan-Charvet L, Sadreyev RI, Nahrendorf M, Westerterp M, Tall AR, Gustafsson JA, Swirski FK

Liver X receptors are required for thymic resilience and T cell output. J Exp Med. 2020;217(10):ePub - PMID: 32716519 - PMCID: PMC7537384 - DOI: 10.1084/jem.20200318

Gerhard GM, Bill R, Messemaker M, Klein AM, Pittet MJ

Tumor-infiltrating dendritic cell states are conserved across solid human cancers. J Exp Med. 2021;218(1):ePub - PMID: 33601412 - PMCID: PMC7754678 - DOI: 10.1084/jem.20200264

Tseng SY, Otsuji M, Gorski K, Huang X, Slansky JE, Pai SI, Shalabi A, Shin T, Pardoll DM, Tsuchiya H

B7-DC, a new dendritic cell molecule with potent costimulatory properties for T cells. J Exp Med. 2001;193(7):839-46 - PMID: 11283156 - PMCID: PMC2193370 - DOI: 10.1084/jem.193.7.839

Han MH, Lundgren DH, Jaiswal S, Chao M, Graham KL, Garris CS, Axtell RC, Ho PP, Lock CB, Woodard JI, Brownell SE, Zoudilova M, Hunt JF, Baranzini SE, Butcher EC, Raine CS, Sobel RA, Han DK, Weissman I, Steinman L

Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice. J Exp Med. 2012;209(7):1325-34 - PMID: 22734047 - PMCID: PMC3405500 - DOI: 10.1084/jem.20101974

McAlpine CS, Kiss MG, Zuraikat FM, Cheek D, Schiroli G, Amatullah H, Huynh P, Bhatti MZ, Wong LP, Yates AG, Poller WC, Mindur JE, Chan CT, Janssen H, Downey J, Singh S, Sadreyev RI, Nahrendorf M, Jeffrey KL, Scadden DT, Naxerova K, St-Onge MP, Swirski FK

Sleep exerts lasting effects on hematopoietic stem cell function and diversity. J Exp Med. 2022;219(11):ePub - PMID: 36129517 - PMCID: PMC9499822 - DOI: 10.1084/jem.20220081

Wang Y, Cao T, Ko J, Shen Y, Zong W, Sheng K, Cao W, Sun S, Cai L, Zhou YL, Zhang XX, Zong C, Weissleder R, Weitz D

Dissolvable Polyacrylamide Beads for High-Throughput Droplet DNA Barcoding. Adv Sci. 2020;7(8):1903463 - PMID: 32328429 - PMCID: PMC7175265 - DOI: 10.1002/advs.201903463

Pai SI, Marincola FM

Peripheral Circulating CD45RA-FOXP3hi T Regulatory (TReg) II Cells Provide a Window into the Activity of Intratumoral TReg Cells. Trends Cancer. 2019;6(1):3-6 - PMID: 31952778 - PMCID: PMC7390988 - DOI: 10.1016/j.trecan.2019.11.003

Parvanian S, Ge X, Garris CS

Recent developments in myeloid immune modulation in cancer therapy. Trends Cancer. 2025;11(4):365-375 - PMID: 39794212 - DOI: 10.1016/j.trecan.2024.12.003

Shaw SY

Molecular imaging in cardiovascular disease: targets and opportunities. Nat Rev Cardiol. 2009;6(9):569-79 - PMID: 19621013 - DOI: 10.1038/nrcardio.2009.119

Swirski FK, Nahrendorf M

Inflammation: Old, caffeinated, and healthy. Nat Rev Cardiol. 2017;14(4):194-196 - PMID: 28250451 - DOI: 10.1038/nrcardio.2017.22

Swirski FK

Inflammation and CVD in 2017: From clonal haematopoiesis to the CANTOS trial. Nat Rev Cardiol. 2017;15(2):79-80 - PMID: 29263444 - DOI: 10.1038/nrcardio.2017.208

Duivenvoorden R, Senders ML, van Leent MMT, Pérez-Medina C, Nahrendorf M, Fayad ZA, Mulder WJM

Nanoimmunotherapy to treat ischaemic heart disease. Nat Rev Cardiol. 2019;16(1):21-32 - PMID: 30209355 - PMCID: PMC10621601 - DOI: 10.1038/s41569-018-0073-1

Kalman JM, Lavandero S, Mahfoud F, Nahrendorf M, Yacoub MH, Zhao D

Looking back and thinking forwards - 15 years of cardiology and cardiovascular research. Nat Rev Cardiol. 2019;16(11):651-660 - PMID: 31570832 - DOI: 10.1038/s41569-019-0261-7

Grune J, Yamazoe M, Nahrendorf M

Electroimmunology and cardiac arrhythmia. Nat Rev Cardiol. 2021;18(8):547-564 - PMID: 33654273 - PMCID: PMC9703448 - DOI: 10.1038/s41569-021-00520-9

Araki M, Park SJ, Dauerman HL, Uemura S, Kim JS, Di Mario C, Johnson TW, Guagliumi G, Kastrati A, Joner M, Holm NR, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski MP, Gonzalo N, Tearney GJ, Bouma B, Aguirre AD, Mintz GS, Stone GW, Bourantas CV, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong MK, Jang Y, Cho JM, Yan BP, Porto I, Niccoli G, Montone RA, Thondapu V, Papafaklis MI, Michalis LK, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel OC, Kurihara O, Soeda T, Sugiyama T, Kim HO, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski KL, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers LM, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto FJ, Waksman R, Garcia-Garcia HM, Maehara A, Ali Z, Finn AV, Virmani R, Kini AS, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada JF, Lerman A, Prasad A, Regar E, Saito Y, Sankardas MA, Subban V, Weissman NJ, Chen Y, Yu B, Nicholls SJ, Barlis P, West NEJ, Arbab-Zadeh A, Ye JC, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang IK

Optical coherence tomography in coronary atherosclerosis assessment and intervention. Nat Rev Cardiol. 2022;19(10):684-703 - PMID: 35449407 - PMCID: PMC9982688 - DOI: 10.1038/s41569-022-00687-9

Araki M, Park SJ, Dauerman HL, Uemura S, Kim JS, Di Mario C, Johnson TW, Guagliumi G, Kastrati A, Joner M, Holm NR, Alfonso F, Wijns W, Adriaenssens T, Nef H, Rioufol G, Amabile N, Souteyrand G, Meneveau N, Gerbaud E, Opolski MP, Gonzalo N, Tearney GJ, Bouma B, Aguirre AD, Mintz GS, Stone GW, Bourantas CV, Räber L, Gili S, Mizuno K, Kimura S, Shinke T, Hong MK, Jang Y, Cho JM, Yan BP, Porto I, Niccoli G, Montone RA, Thondapu V, Papafaklis MI, Michalis LK, Reynolds H, Saw J, Libby P, Weisz G, Iannaccone M, Gori T, Toutouzas K, Yonetsu T, Minami Y, Takano M, Raffel OC, Kurihara O, Soeda T, Sugiyama T, Kim HO, Lee T, Higuma T, Nakajima A, Yamamoto E, Bryniarski KL, Di Vito L, Vergallo R, Fracassi F, Russo M, Seegers LM, McNulty I, Park S, Feldman M, Escaned J, Prati F, Arbustini E, Pinto FJ, Waksman R, Garcia-Garcia HM, Maehara A, Ali Z, Finn AV, Virmani R, Kini AS, Daemen J, Kume T, Hibi K, Tanaka A, Akasaka T, Kubo T, Yasuda S, Croce K, Granada JF, Lerman A, Prasad A, Regar E, Saito Y, Sankardas MA, Subban V, Weissman NJ, Chen Y, Yu B, Nicholls SJ, Barlis P, West NEJ, Arbab-Zadeh A, Ye JC, Dijkstra J, Lee H, Narula J, Crea F, Nakamura S, Kakuta T, Fujimoto J, Fuster V, Jang IK

Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention. Nat Rev Cardiol. 2023;21(5):348 - PMID: 38110566 - PMCID: PMC11987009 - DOI: 10.1038/s41569-023-00982-z

Eddowes LA, Al-Hourani K, Ramamurthy N, Frankish J, Baddock HT, Sandor C, Ryan JD, Fusco DN, Arezes J, Giannoulatou E, Boninsegna S, Chevaliez S, Owens BMJ, Sun CC, Fabris P, Giordani MT, Martines D, Vukicevic S, Crowe J, Lin HY, Rehwinkel J, McHugh PJ, Binder M, Babitt JL, Chung RT, Lawless MW, Armitage AE, Webber C, Klenerman P, Drakesmith H

Antiviral activity of bone morphogenetic proteins and activins. Nat Microbiol. 2018;4(2):339-351 - PMID: 30510168 - PMCID: PMC6590058 - DOI: 10.1038/s41564-018-0301-9

Tang J, Lobatto ME, Hassing L, van der Staay S, van Rijs SM, Calcagno C, Braza MS, Baxter S, Fay F, Sanchez-Gaytan BL, Duivenvoorden R, Sager H, Astudillo YM, Leong W, Ramachandran S, Storm G, Pérez-Medina C, Reiner T, Cormode DP, Strijkers GJ, Stroes ES, Swirski FK, Nahrendorf M, Fisher EA, Fayad ZA, Mulder WJ

Inhibiting macrophage proliferation suppresses atherosclerotic plaque inflammation. Sci Adv. 2015;1(3):ePub - PMID: 26295063 - PMCID: PMC4539616 - DOI: 10.1126/sciadv.1400223

Park KS*, Huang CH*, Lee K, Yoo YE, Castro CM, Weissleder R, Lee H

Rapid identification of health care–associated infections with an integrated fluorescence anisotropy system Sci Adv. 2016;2(5):e1600300 - PMID: 28861468 - PMCID: PMC5565941 - DOI: 10.1126/sciadv.1600300

Jeong S, Eskandari R, Park SM, Alvarez J, Tee SS, Weissleder R, Kharas MG, Lee H, Keshari KR

Real-time quantitative analysis of metabolic flux in live cells using a hyperpolarized micromagnetic resonance spectrometer. Sci Adv. 2017;3(6):e1700341 - PMID: 28630930 - PMCID: PMC5473678 - DOI: 10.1126/sciadv.1700341

Ricklefs FL, Alayo Q, Krenzlin H, Mahmoud AB, Speranza MC, Nakashima H, Hayes JL, Lee K, Balaj L, Passaro C, Rooj AK, Krasemann S, Carter BS, Chen CC, Steed T, Treiber J, Rodig S, Yang K, Nakano I, Lee H, Weissleder R, Breakefield XO, Godlewski J, Westphal M, Lamszus K, Freeman GJ, Bronisz A, Lawler SE, Chiocca EA

Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles. Sci Adv. 2018;4(3):eaar2766 - PMID: 29532035 - PMCID: PMC5842038 - DOI: 10.1126/sciadv.aar2766

Wang SJ, Li R, Ng TSC, Luthria G, Oudin MJ, Prytyskach M, Kohler RH, Weissleder R, Lauffenburger DA, Miller MA

Efficient blockade of locally reciprocated tumor-macrophage signaling using a TAM-avid nanotherapy. Sci Adv. 2020;6(21):ePub - PMID: 32937338 - PMCID: PMC7244320 - DOI: 10.1126/sciadv.aaz8521

Liebel M, Ortega Arroyo J, Beltrán VS, Osmond J, Jo A, Lee H, Quidant R, van Hulst NF

3D tracking of extracellular vesicles by holographic fluorescence imaging. Sci Adv. 2020;6(45):ePub - PMID: 33148645 - PMCID: PMC7673696 - DOI: 10.1126/sciadv.abc2508

Ferguson S, Yang KS, Zelga P, Liss AS, Carlson JCT, Del Castillo CF, Weissleder R

Single-EV analysis (sEVA) of mutated proteins allows detection of stage 1 pancreatic cancer. Sci Adv. 2022;8(16):eabm3453 - PMID: 35452280 - PMCID: PMC9032977 - DOI: 10.1126/sciadv.abm3453

Ng TSC, Hu H, Kronister S, Lee C, Li R, Gerosa L, Stopka SA, Burgenske DM, Khurana I, Regan MS, Vallabhaneni S, Putta N, Scott E, Matvey D, Giobbie-Hurder A, Kohler RH, Sarkaria JN, Parangi S, Sorger PK, Agar NYR, Jacene HA, Sullivan RJ, Buchbinder E, Mikula H, Weissleder R, Miller MA

Overcoming differential tumor penetration of BRAF inhibitors using computationally guided combination therapy. Sci Adv. 2022;8(17):eabl6339 - PMID: 35486732 - PMCID: PMC9054019 - DOI: 10.1126/sciadv.abl6339

Cho YK, Kim H, Bénard A, Woo HK, Czubayko F, David P, Hansen FJ, Lee JI, Park JH, Schneck E, Weber GF, Shin IK, Lee H

Electrochemiluminescence in paired signal electrode (ECLipse) enables modular and scalable biosensing Sci Adv. 2022;8:eabq4022 - PMID: 36129990 - PMCID: PMC9491722 - DOI: 10.1126/sciadv.abq4022

Choi Y, Park JH, Jo A, Lim CW, Park JM, Hwang JW, Lee KS, Kim YS, Lee H, Moon J

Blood-derived APLP1+ extracellular vesicles are potential biomarkers for the early diagnosis of brain diseases. Sci Adv. 2025;11(1):eado6894 - PMID: 39742488 - PMCID: PMC11691634 - DOI: 10.1126/sciadv.ado6894

Gong D, Liu R, Cui Y, Rhodes M, Bae JW, Beechem JM, Hwang WL

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer. Sci Adv. 2025;11(42):eadx0632 - PMID: 41105767 - PMCID: PMC12533583 - DOI: 10.1126/sciadv.adx0632

Deutsch-Williams RJ, Xie Y, Rabinowitz Z, Goemans M, Wirapati P, Vinegoni C, Carlson JCT, Pittet M, Weissleder R

Targeting cancer-­ associated fibroblasts for real-­ time intraoperative tumor identification with a spray-­on fluorescent probe Sci Adv. 2025;11(47):eaeb5810 - PMID: 41259533 - PMCID: PMC12629203 - DOI: 10.1126/sciadv.aeb5810

Osborn EA, Jaffer FA

The year in molecular imaging. JACC Cardiovasc Imaging. 2010;3(11):1181-95 - PMID: 21071007 - PMCID: PMC3057415 - DOI: 10.1016/j.jcmg.2010.09.009

Hara T, Bhayana B, Thompson B, Kessinger CW, Khatri A, McCarthy JR, Weissleder R, Lin CP, Tearney GJ, Jaffer FA

Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence. JACC Cardiovasc Imaging. 2012;5(6):607-15 - PMID: 22698530 - PMCID: PMC3376390 - DOI: 10.1016/j.jcmg.2012.01.017

Chen JW, Figueiredo JL, Wojtkiewicz GR, Siegel C, Iwamoto Y, Kim DE, Nolte MW, Dickneite G, Weissleder R, Nahrendorf M

Selective Factor XIIa Inhibition Attenuates Silent Brain Ischemia: Application of Molecular Imaging Targeting Coagulation Pathway. JACC Cardiovasc Imaging. 2012;5(11):1127-38 - PMID: 23153913 - PMCID: PMC3502014 - DOI: 10.1016/j.jcmg.2012.01.025

Emami H, Singh P, MacNabb M, Vucic E, Lavender Z, Rudd JH, Fayad ZA, Lehrer-Graiwer J, Korsgren M, Figueroa AL, Fredrickson J, Rubin B, Hoffmann U, Truong QA, Min JK, Baruch A, Nasir K, Nahrendorf M, Tawakol A

Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans. JACC Cardiovasc Imaging. 2015;8(2):121-30 - PMID: 25577441 - PMCID: PMC6855915 - DOI: 10.1016/j.jcmg.2014.10.009

Nahrendorf M, Swirski FK

PET Imaging of Leukocytes in Patients With Acute Myocardial Infarction. JACC Cardiovasc Imaging. 2015;8(12):1427-9 - PMID: 26699111 - DOI: 10.1016/j.jcmg.2015.10.004

Nahrendorf M, Vandoorne K

Albumin-Binding MR Probe Detects High-Risk Coronary Plaques in Patients. JACC Cardiovasc Imaging. 2018;12(2):307-309 - PMID: 29361477 - DOI: 10.1016/j.jcmg.2017.11.026

Nahrendorf M

Multiorgan Imaging of Comorbidity and Cardiovascular Risk. JACC Cardiovasc Imaging. 2018;13(2 Pt 1):478-480 - PMID: 30448129 - DOI: 10.1016/j.jcmg.2018.09.017

Foy BH, Gonçalves BP, Higgins JM

Unraveling Disease Pathophysiology with Mathematical Modeling. Annu Rev Pathol. 2020;15:371-394 - PMID: 31977295 - DOI: 10.1146/annurev-pathmechdis-012419-032557

Pai SI, Westra WH

Molecular pathology of head and neck cancer: implications for diagnosis, prognosis, and treatment. Annu Rev Pathol. 2009;4:49-70 - PMID: 18729723 - PMCID: PMC3703474 - DOI: 10.1146/annurev.pathol.4.110807.092158

Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D.

Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes J Clin Invest. 2005;115(9):2454-2461 - PMID: 16110329 - PMCID: PMC1187933 - DOI: 10.1172/JCI25048

Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ

Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata J Clin Invest. 2007;117(1):195-205 - PMID: 17200719 - PMCID: PMC1716211 - DOI: 10.1172/JCI29950

Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest. 2007;117(7):1933-1939 - PMID: 17607365 - PMCID: PMC1904317 - DOI: 10.1172/JCI31342

Ducharme A, Frantz S, Aikawa M, Rabkin E, Lindsey M, Rohde L, Schoen F, Kelly R, Werb Z, Libby P, Lee R

Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest. 2000;106:55-62 - PMID: 10880048 - PMCID: PMC517910 - DOI: 10.1172/JCI8768

Laufs U, Endres M, Stagliano N, Amin-Hanjani S, Chui D, Yang S, Simoncini T, Yamada M, Rabkin E, Allen P, Huang P, Bahm M, Schoen F, Moskowitz M, Liao J

Neuroprotection mediated by changes in the endothelial actin cytoskeleton. J Clin Invest. 2000;106:15-24 - PMID: 10880044 - PMCID: PMC314365 - DOI: 10.1172/JCI9639

Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ

Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation J Clin Invest. 2008;118(12):4058-66 - PMID: 19033674 - PMCID: PMC2579705 - DOI: 10.1172/JCI36335

Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK

A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008;:ePub - PMID: 19005570 - PMCID: PMC2579884

Wang L, Harrington L, Trebicka E, Shi HN, Kagan JC, Hong CC, Lin HY, Babitt JL, Cherayil BJ

Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice. J Clin Invest. 2009;119(11):3322-8 - PMID: 19809161 - PMCID: PMC2769199 - DOI: 10.1172/JCI39939

Ueno T, Habicht A, Clarkson MR, Albin MJ, Yamaura K, Boenisch O, Popoola J, Wang Y, Yagita H, Akiba H, Ansari MJ, Yang J, Turka LA, Rothstein DM, Padera RF, Najafian N, Sayegh MH

The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest. 2008;118(2):742-51 - PMID: 18172549 - PMCID: PMC2157561 - DOI: 10.1172/JCI32451

Swirski FK, Wildgruber M, Ueno T, Figueiredo JL, Panizzi P, Iwamoto Y, Zhang E, Stone JR, Rodriguez E, Chen JW, Pittet MJ, Weissleder R, Nahrendorf M

Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice. J Clin Invest. 2010;120(7):2627-34 - PMID: 20577051 - PMCID: PMC2898607 - DOI: 10.1172/JCI42304

Gaglia JL, Guimaraes AR, Harisinghani M, Turvey SE, Jackson R, Benoist C, Mathis D, Weissleder R

Noninvasive imaging of pancreatic islet inflammation in type 1A diabetes patients. J Clin Invest. 2010;121(1):442-5 - PMID: 21123946 - PMCID: PMC3007157 - DOI: 10.1172/JCI44339

Bouley R, Breton S, Sun T, McLaughlin M, Nsumu NN, Lin HY, Ausiello DA, Brown D

Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells. J Clin Invest. 2000;106(9):1115-26 - PMID: 11067864 - PMCID: PMC301414 - DOI: 10.1172/JCI9594

Choukroun GJ, Marshansky V, Gustafson CE, McKee M, Hajjar RJ, Rosenzweig A, Brown D, Bonventre JV

Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins. J Clin Invest. 2000;106(8):983-93 - PMID: 11032858 - PMCID: PMC314339 - DOI: 10.1172/JCI8914

Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V

Evidence for bistable bacteria-neutrophil interaction and its clinical implications. J Clin Invest. 2012;122(8):3002-11 - PMID: 22820292 - PMCID: PMC3408731 - DOI: 10.1172/JCI59832

Xie Q, Wu Q, Kim L, Miller TE, Liau BB, Mack SC, Yang K, Factor DC, Fang X, Huang Z, Zhou W, Alazem K, Wang X, Bernstein BE, Bao S, Rich JN

RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation. J Clin Invest. 2016;126(7):2757-72 - PMID: 27322055 - PMCID: PMC4922685 - DOI: 10.1172/JCI86114

Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ

mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors. J Clin Invest. 2017;127(6):2433-2437 - PMID: 28481220 - PMCID: PMC5451245 - DOI: 10.1172/JCI92030

Hulsmans M, Nahrendorf M

Proliferative, degradative smooth muscle cells promote aortic disease. J Clin Invest. 2020;130(3):1096-1098 - PMID: 32039919 - PMCID: PMC7269557 - DOI: 10.1172/JCI134019

Battistone MA, Mendelsohn AC, Spallanzani RG, Allegretti AS, Liberman RN, Sesma J, Kalim S, Wall SM, Bonventre JV, Lazarowski ER, Brown D, Breton S

Pro-inflammatory P2Y14 receptor inhibition protects against ischemic acute kidney injury in mice. J Clin Invest. 2020;130(7):3734-3749 - PMID: 32287042 - PMCID: PMC7324186 - DOI: 10.1172/JCI134791

Qin T, Mattox AK, Campbell JS, Park JC, Shin KY, Li S, Sadow PM, Faquin WC, Micevic G, Daniels AJ, Haddad R, Garris CS, Pittet MJ, Mempel TR, ONeill A, Sartor MA, Pai SI

Epigenetic therapy sensitizes anti-PD-1 refractory head and neck cancers to immunotherapy rechallenge. J Clin Invest. 2025;135(6):ePub - PMID: 40091844 - PMCID: PMC11910227 - DOI: 10.1172/JCI181671

Ko J, Oh J, Ahmed MS, Carlson JCT, Weissleder R

Ultra-fast cycling for multiplexed cellular fluorescence imaging. Angew Chem Weinheim Bergstr Ger. 2020;132(17):6906-6913 - PMID: 34366494 - PMCID: PMC8340598 - DOI: 10.1002/ange.201915153

Tung CH, Weissleder R

Arginine containing peptides as delivery vectors Adv Drug Deliv Rev. 2003;55:281-94 - PMID: 12564981 - DOI: 10.1016/s0169-409x(02)00183-7

Bogdanov AA, Lewin M, Weissleder R

Approaches and agents for imaging the vascular system Adv Drug Deliv Rev. 1999;37:279-293 - PMID: 10837740 - DOI: 10.1016/s0169-409x(98)00098-2

McCarthy JR, Weissleder R

Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev. 2008;60:1241-1251 - PMID: 18508157 - PMCID: PMC2583936 - DOI: 10.1016/j.addr.2008.03.014

McCarthy JR

Multifunctional agents for concurrent imaging and therapy in cardiovascular disease. Adv Drug Deliv Rev. 2010;62(11):1023-30 - PMID: 20654664 - PMCID: PMC2974776 - DOI: 10.1016/j.addr.2010.07.004

Weissleder R, Bogdanov A, Neuwelt EA, Papisov M

Long-circulating iron oxides for MR imaging Adv Drug Deliv Rev. 1995;16:321-334

Bogdanov A, Weissleder R, Brady T

Long-circulating blood pool imaging agents Adv Drug Deliv Rev. 1995;15:335-348

Shah K

Mesenchymal stem cells engineered for cancer therapy. Adv Drug Deliv Rev. 2011;64(8):739-48 - PMID: 21740940 - PMCID: PMC3395998 - DOI: 10.1016/j.addr.2011.06.010

Miller MA, Weissleder R

Imaging the pharmacology of nanomaterials by intravital microscopy: Towards understanding their biological behavior. Adv Drug Deliv Rev. 2017;113:61-86 - PMID: 27266447 - PMCID: PMC5136524 - DOI: 10.1016/j.addr.2016.05.023

Alaarg A, Pérez-Medina C, Metselaar JM, Nahrendorf M, Fayad ZA, Storm G, Mulder WJM

Applying nanomedicine in maladaptive inflammation and angiogenesis. Adv Drug Deliv Rev. 2017;119:143-158 - PMID: 28506745 - PMCID: PMC5682240 - DOI: 10.1016/j.addr.2017.05.009

Miller MA, Weissleder R

Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior Adv Drug Deliv Rev. 2017;113:61-86 - PMID: 27266447 - PMCID: PMC5136524 - DOI: 10.1016/j.addr.2016.05.023

Vinegoni C, Feruglio PF, Gryczynski I, Mazitschek R, Weissleder R

Fluorescence anisotropy imaging in drug discovery. Adv Drug Deliv Rev. 2018;151-152:262-288 - PMID: 29410158 - PMCID: PMC6072632 - DOI: 10.1016/j.addr.2018.01.019

Hu H, Quintana J, Weissleder R, Parangi S, Miller M

Deciphering albumin-directed drug delivery by imaging. Adv Drug Deliv Rev. 2022;185:114237 - PMID: 35364124 - PMCID: PMC9117484 - DOI: 10.1016/j.addr.2022.114237

Hwang WL, Pleskow HM, Miyamoto DT

Molecular analysis of circulating tumors cells: Biomarkers beyond enumeration. Adv Drug Deliv Rev. 2018;125:122-131 - PMID: 29326053 - DOI: 10.1016/j.addr.2018.01.003

Pai SI, Matheus HR, Guastaldi FPS

Effects of periodontitis on cancer outcomes in the era of immunotherapy. Lancet Healthy Longev. 2023;4(4):e166-e175 - PMID: 37003275 - PMCID: PMC10148268 - DOI: 10.1016/S2666-7568(23)00021-1

Yang Z*, Francisco J*, Reese AS, Spriggs DR, Im H, Castro CM

Addressing cervical cancer screening disparities through advances in artificial intelligence and nanotechnologies for cellular profiling. Biophys Rev. 2021;2:011303 - PMID: 33842926 - PMCID: PMC8015256 - DOI: 10.1063/5.0043089

Vilardaga JP

Switching modes for G protein-coupled receptor activation. Nat Chem Biol. 2006;2(8):395-6 - PMID: 16850011 - DOI: 10.1038/nchembio0806-395

Yu PB, Hong CC, Sachidanandan C, Babitt JL, Deng DY, Hoyng SA, Lin HY, Bloch KD, Peterson RT

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2007;4(1):33-41 - PMID: 18026094 - PMCID: PMC2727650 - DOI: 10.1038/nchembio.2007.54

Vilardaga JP, Nikolaev VO, Lorenz K, Ferrandon S, Zhuang Z, Lohse MJ

Conformational cross-talk between alpha(2A)-adrenergic and mu-opioid receptors controls cell signaling. Nat Chem Biol. 2008;4:126-131 - PMID: 18193048 - DOI: 10.1038/nchembio.64

Ferrandon S, Feinstein TN, Castro M, Wang B, Bouley R, Potts JT, Gardella TJ, Vilardaga JP

Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. Nat Chem Biol. 2009;5(10):734-42 - PMID: 19701185 - PMCID: PMC3032084 - DOI: 10.1038/nchembio.206

Bradner JE, West N, Grachan ML, Greenberg EF, Haggarty SJ, Warnow T, Mazitschek R

Chemical phylogenetics of histone deacetylases. Nat Chem Biol. 2010;6(3):238-243 - PMID: 20139990 - PMCID: PMC2822059 - DOI: 10.1038/nchembio.313

Keller TL, Zocco D, Sundrud MS, Hendrick M, Edenius M, Yum J, Kim YJ, Lee HK, Cortese JF, Wirth DF, Dignam JD, Rao A, Yeo CY, Mazitschek R, Whitman M

Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase Nat Chem Biol. 2012;8(3):311-7 - PMID: 22327401 - PMCID: PMC3281520 - DOI: 10.1038/nchembio.790

Reis SA, Ghosh B, Hendricks JA, Szantai-Kis DM, Törk L, Ross KN, Lamb J, Read-Button W, Zheng B, Wang H, Salthouse C, Haggarty SJ, Mazitschek R

Light-controlled modulation of gene expression by chemical optoepigenetic probes. Nat Chem Biol. 2016;12(5):317-323 - PMID: 26974814 - PMCID: PMC4836974 - DOI: 10.1038/nchembio.2042

Dubach JM, Kim E, Yang K, Cuccarese M, Giedt RJ, Meimetis LG, Vinegoni C, Weissleder R

Quantitating drug-target engagement in single cells in vitro and in vivo. Nat Chem Biol. 2016;13(2):168-173 - PMID: 27918558 - PMCID: PMC5630128 - DOI: 10.1038/nchembio.2248

Payne NC, Kalyakina AS, Singh K, Tye MA, Mazitschek R

Bright and stable luminescent probes for target engagement profiling in live cells. Nat Chem Biol. 2021;17(11):1168-1177 - PMID: 34675420 - PMCID: PMC8555866 - DOI: 10.1038/s41589-021-00877-5

Isono K, Endo TA, Ku M, Yamada D, Suzuki R, Sharif J, Ishikura T, Toyoda T, Bernstein BE, Koseki H

SAM Domain Polymerization Links Subnuclear Clustering of PRC1 to Gene Silencing. Dev Cell. 2013;26(6):565-577 - PMID: 24091011 - DOI: 10.1016/j.devcel.2013.08.016

Ozturk H, Cingoz H, Tufan T, Yang J, Adair SJ, Tummala KS, Kuscu C, Kinali M, Comertpay G, Nagdas S, Goudreau BJ, Luleyap HU, Bingul Y, Ware TB, Hwang WL, Hsu KL, Kashatus DF, Ting DT, Chandel NS, Bardeesy N, Bauer TW, Adli M

ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer. Dev Cell. 2022;57(11):1331-1346.e9 - PMID: 35508175 - DOI: 10.1016/j.devcel.2022.04.014

Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R

Imaging inflammation of the pancreatic islets in type 1 diabetes. Proc Natl Acad Sci U S A. 2004;101(34):12634-9 - PMID: 15304647 - PMCID: PMC515109 - DOI: 10.1073/pnas.0404307101

Ntziachristos V, Schellenberger EA, Ripoll J, Yessayan D, Graves E, Bogdanov A Jr, Josephson L, Weissleder R

Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc Natl Acad Sci U S A. 2004;101(33):12294-9 - PMID: 15304657 - PMCID: PMC514472 - DOI: 10.1073/pnas.0401137101

Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K.

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-{beta} signals in vivo Proc Natl Acad Sci U S A. 2005;102(2):419-24 - PMID: 15623559 - PMCID: PMC544311 - DOI: 10.1073/pnas.0408197102

Grimm J, Kirsch DG, Windsor SD, Kim CF, Santiago PM, Ntziachristos V, Jacks T, Weissleder R.

Use of gene expression profiling to direct in vivo molecular imaging of lung cancer Proc Natl Acad Sci U S A. 2005;102(40):14404-14409 - PMID: 16183744 - PMCID: PMC1242291 - DOI: 10.1073/pnas.0503920102

Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V.

Volumetric tomography of fluorescent proteins through small animals in vivo Proc Natl Acad Sci U S A. 2005;102:18252-18257 - PMID: 16344470 - PMCID: PMC1317905 - DOI: 10.1073/pnas.0504628102

Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA

Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006;103:5947-5952 - PMID: 16585505 - PMCID: PMC1458678 - DOI: 10.1073/pnas.0601273103

Swirski FK, Pittet MJ, Kircher MF, Aikawa E, Jaffer FA, Libby P, Weissleder R

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A. 2006;103(27):10340-5 - PMID: 16801531 - PMCID: PMC1502459 - DOI: 10.1073/pnas.0604260103

Fulci G, Breymann L,Gianni D, Kurozomi K, Rhee S, Yu J, Kaur B, Louis D, Weissleder R, Caligiuri M, Chiocca A.

Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses Proc Natl Acad Sci U S A. 2006;103:12873-12878 - PMID: 16908838 - PMCID: PMC1568940 - DOI: 10.1073/pnas.0605496103

Finberg KE, Wagner CA, Bailey MA, Paunescu TG, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP

The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A. 2005;102(38):13616-21 - PMID: 16174750 - PMCID: PMC1224669 - DOI: 10.1073/pnas.0506769102

Pittet M, Grimm J, Berger C, Tamura T, Wojtkiewicz G, Nahrendorf M, Romero P, Swirski F, Weissleder R.

In vivo imaging of T cell delivery to tumors after adoptive transfer therapy Proc Natl Acad Sci U S A. 2007;104:12457-12461 - PMID: 17640914 - PMCID: PMC1941490 - DOI: 10.1073/pnas.0704460104

Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K

Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A. 2007;104:19977-82 - PMID: 18077429 - PMCID: PMC2148408 - DOI: 10.1073/pnas.0704620104

Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R

Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A. 2008;105:7387-7392 - PMID: 18492802 - PMCID: PMC2396702 - DOI: 10.1073/pnas.0802878105

Gold L, Brown D, He Y, Shtatland T, Singer B, Wu Y

From oligonucleotide shapes to genomic SELEX: novel biological regulatory loops. Proc Natl Acad Sci U S A. 1997;94:59-64 - PMID: 8990161 - PMCID: PMC19236 - DOI: 10.1073/pnas.94.1.59

Hahn C, Ross K, Warrington I, Mazitschek R, Kanegai C, Wright R, Kung A, Golub T, Stegmaier K

Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation. Proc Natl Acad Sci U S A. 2008;105(28):9751-6 - PMID: 18607002 - PMCID: PMC2474517 - DOI: 10.1073/pnas.0710413105

Shaw S, Wang J

Chirality of DNA trefoils: implications in intramolecular synapsis of distant DNA segments. Proc Natl Acad Sci U S A. 1997;94(5):1692-7 - PMID: 9050840 - PMCID: PMC19978 - DOI: 10.1073/pnas.94.5.1692

Breckwoldt M*, Chen JW*, Stangenberg L, Aikawa E, Rodriguez E, Qiu S, Moskowitz M, Weissleder R

Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase Proc Natl Acad Sci U S A. 2008;105 (47):18584-18589 - PMID: 19011099 - PMCID: PMC2587593 - DOI: 10.1073/pnas.0803945105

Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V

Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. Proc Natl Acad Sci U S A. 2008;105(49)::19126-19131 - PMID: 19015534 - PMCID: PMC2614726 - DOI: 10.1073/pnas.0804798105

Okazaki M, Ferrandon S, Vilardaga J, Bouxsein M, Potts J, Gardella T

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A. 2008;105(43):16525-30 - PMID: 18946036 - PMCID: PMC2571912 - DOI: 10.1073/pnas.0808750105

Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Bronson R, Chen J, Weissleder R, Housman D, Charest A.

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene function in gliomagenesis Proc Natl Acad Sci U S A. 0;:ePub

Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Pfannl R, Bronson RT, Chen JW, Weissleder R, Housman DE, Charest A

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene functions in gliomagenesis. Proc Natl Acad Sci U S A. 2009;106(8):2712-6 - PMID: 19196966 - PMCID: PMC2650331 - DOI: 10.1073/pnas.0813314106

Sasportas LS, Kasmieh R, Wakimoto H, Hingtgen S, van de Water JA, Mohapatra G, Figueiredo JL, Martuza RL, Weissleder R, Shah K

Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc Natl Acad Sci U S A. 2009;106(12):4822-7 - PMID: 19264968 - PMCID: PMC2660771 - DOI: 10.1073/pnas.0806647106

Butcher R, Ragains J, Li W, Ruvkun G, Clardy J, Mak H

Biosynthesis of the Caenorhabditis elegans dauer pheromone. Proc Natl Acad Sci U S A. 2009;106(6):1875-9 - PMID: 19174521 - PMCID: PMC2631283 - DOI: 10.1073/pnas.0810338106

Kroh H, Panizzi P, Bock P

Von Willebrand factor-binding protein is a hysteretic conformational activator of prothrombin. Proc Natl Acad Sci U S A. 2009;106(19):7786-91 - PMID: 19416890 - PMCID: PMC2683071 - DOI: 10.1073/pnas.0811750106

Lee H*, Yoon TJ*, Figueiredo JL, Swirski FK, Weissleder R

Rapid detection and profiling of cancer cells in fine-needle aspirates. Proc Natl Acad Sci U S A. 2009;106 (30):12459-12464 - PMID: 19620715 - PMCID: PMC2718371 - DOI: 10.1073/pnas.0902365106

Yoo B, Gredler R, Vozhilla N, Su Z, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher P, Sarkar D

Identification of genes conferring resistance to 5-fluorouracil. Proc Natl Acad Sci U S A. 2009;106(31):12938-43 - PMID: 19622726 - PMCID: PMC2722317 - DOI: 10.1073/pnas.0901451106

Berman SD, West JC, Danielian PS, Caron AM, Stone JR, Lees JA

Mutation of p107 exacerbates the consequences of Rb loss in embryonic tissues and causes cardiac and blood vessel defects. Proc Natl Acad Sci U S A. 2009;106(35):14932-6 - PMID: 19706423 - PMCID: PMC2736449 - DOI: 10.1073/pnas.0902408106

Evans C, Potma E, Puoris'haag M, C

Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy. Proc Natl Acad Sci U S A. 2005;102:16807-12 - PMID: 16263923 - PMCID: PMC1283840 - DOI: 10.1073/pnas.0508282102

Higgins JM, Eddington DT, Bhatia SN, Mahadevan L

Sickle cell vasoocclusion and rescue in a microfluidic device. Proc Natl Acad Sci U S A. 2007;104(51):20496-500 - PMID: 18077341 - PMCID: PMC2154459 - DOI: 10.1073/pnas.0707122105

Hung KE, Maricevich MA, Richard LG, Chen WY, Richardson MP, Kunin A, Bronson RT, Mahmood U, Kucherlapati R

Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment. Proc Natl Acad Sci U S A. 2010;107(4):1565-70 - PMID: 20080688 - PMCID: PMC2824379 - DOI: 10.1073/pnas.0908682107

Tsigkou O, Pomerantseva I, Spencer JA, Redondo PA, Hart AR, O'Doherty E, Lin Y, Friedrich CC, Daheron L, Lin CP, Sundback CA, Vacanti JP, Neville C

Regenerative Medicine Special Feature: Engineered vascularized bone grafts. Proc Natl Acad Sci U S A. 2010;107(8):3311-6 - PMID: 20133604 - PMCID: PMC2840421 - DOI: 10.1073/pnas.0905445107

Vallet S, Mukherjee S, Vaghela N, Hideshima T, Fulciniti M, Pozzi S, Santo L, Cirstea D, Patel K, Sohani AR, Guimaraes A, Xie W, Chauhan D, Schoonmaker JA, Attar E, Churchill M, Weller E, Munshi N, Seehra JS, Weissleder R, Anderson KC, Scadden DT, Raje N

Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease. Proc Natl Acad Sci U S A. 2010;107(11):5124-9 - PMID: 20194748 - PMCID: PMC2841922 - DOI: 10.1073/pnas.0911929107

Nahrendorf M, Keliher E, Marinelli B, Waterman P, Feruglio PF, Fexon L, Pivovarov M, Swirski FK, Pittet MJ, Vinegoni C, Weissleder R

Hybrid PET-optical imaging using targeted probes Proc Natl Acad Sci U S A. 2010;107(17):7910-5 - PMID: 20385821 - PMCID: PMC2867879 - DOI: 10.1073/pnas.0915163107

Bradner JE, Mak R, Tanguturi SK, Mazitschek R, Haggarty SJ, Ross K, Chang CY, Bosco J, West N, Morse E, Lin K, Shen JP, Kwiatkowski NP, Gheldof N, Dekker J, Deangelo DJ, Carr SA, Schreiber SL, Golub TR, Ebert BL

Chemical genetic strategy identifies histone deacetylase 1 (HDAC1) and HDAC2 as therapeutic targets in sickle cell disease. Proc Natl Acad Sci U S A. 2010;107(28):12617-22 - PMID: 20616024 - PMCID: PMC2906581 - DOI: 10.1073/pnas.1006774107

Higgins JM, Mahadevan L

Physiological and pathological population dynamics of circulating human red blood cells. Proc Natl Acad Sci U S A. 2010;107(47):20587-92 - PMID: 21059904 - PMCID: PMC2996693 - DOI: 10.1073/pnas.1012747107

Gao X, Eladari D, Leviel F, Tew BY, Miro-Julia

Deletion of hensin/DMBT1 blocks conversion of {beta}- to {alpha}-intercalated cells and induces distal renal tubular acidosis. Proc Natl Acad Sci U S A. 2010;107(50):21872-7 - PMID: 21098262 - PMCID: PMC3003085 - DOI: 10.1073/pnas.1010364107

Shaw SY, Blodgett DM, Ma MS, Westly EC, Clemons PA, Subramanian A, Schreiber SL

Disease allele-dependent small-molecule sensitivities in blood cells from monogenic diabetes. Proc Natl Acad Sci U S A. 2010;108(2):492-7 - PMID: 21183721 - PMCID: PMC3021060 - DOI: 10.1073/pnas.1016789108

Grover WH, Bryan AK, Diez-Silva M, Suresh S, Higgins JM, Manalis SR

Measuring single-cell density. Proc Natl Acad Sci U S A. 2011;108(27):10992-10996 - PMID: 21690360 - PMCID: PMC3131325 - DOI: 10.1073/pnas.1104651108

Wang H, Zou J, Zhao B, Johannsen E, Ashworth T, Wong H, Pear WS, Schug J, Blacklow SC, Arnett KL, Bernstein BE, Kieff E, Aster JC

Genome-wide analysis reveals conserved and divergent features of Notch1/RBPJ binding in human and murine T-lymphoblastic leukemia cells. Proc Natl Acad Sci U S A. 2011;108(36):14908-13 - PMID: 21737748 - PMCID: PMC3169118 - DOI: 10.1073/pnas.1109023108

Zhao B, Zou J, Wang H, Johannsen E, Peng CW, Quackenbush J, Mar JC, Morton CC, Freedman ML, Blacklow SC, Aster JC, Bernstein BE, Kieff E

Epstein-Barr virus exploits intrinsic B-lymphocyte transcription programs to achieve immortal cell growth. Proc Natl Acad Sci U S A. 2011;108(36):14902-7 - PMID: 21746931 - PMCID: PMC3169132 - DOI: 10.1073/pnas.1108892108

Reiner T, Thurber G, Gaglia J, Vinegoni C, Liew CW, Upadhyay R, Kohler RH, Li L, Kulkarni RN, Benoist C, Mathis D, Weissleder R

Accurate measurement of pancreatic islet {beta}-cell mass using a second-generation fluorescent exendin-4 analog. Proc Natl Acad Sci U S A. 2011;108(31):12815-20 - PMID: 21768367 - PMCID: PMC3150928 - DOI: 10.1073/pnas.1109859108

Cortez-Retamozo V, Etzrodt M, Newton A, Rauch PJ, Chudnovskiy A, Berger C, Ryan RJ, Iwamoto Y, Marinelli B, Gorbatov R, Forghani R, Novobrantseva TI, Koteliansky V, Figueiredo JL, Chen JW, Anderson DG, Nahrendorf M, Swirski FK, Weissleder R, Pittet MJ

Origins of tumor-associated macrophages and neutrophils. Proc Natl Acad Sci U S A. 2012;109(7):2491-6 - PMID: 22308361 - PMCID: PMC3289379 - DOI: 10.1073/pnas.1113744109

Devaraj NK, Thurber GM, Keliher EJ, Marinelli B, Weissleder R

Reactive polymer enables efficient in vivo bioorthogonal chemistry. Proc Natl Acad Sci U S A. 2012;109(13):4762-7 - PMID: 22411831 - PMCID: PMC3324005 - DOI: 10.1073/pnas.1113466109

Fukuda D, Aikawa E, Swirski FK, Novobrantseva TI, Kotelianski V, Gorgun CZ, Chudnovskiy A, Yamazaki H, Croce K, Weissleder R, Aster JC, Hotamisligil GS, Yagita H, Aikawa M

Notch ligand Delta-like 4 blockade attenuates atherosclerosis and metabolic disorders. Proc Natl Acad Sci U S A. 2012;109(27):E1868-77 - PMID: 22699504 - PMCID: PMC3390871 - DOI: 10.1073/pnas.1116889109

Lee J, Li M, Milwid J, Dunham J, Vinegoni C, Gorbatov R, Iwamoto Y, Wang F, Shen K, Hatfield K, Enger M, Shafiee S, McCormack E, Ebert BL, Weissleder R, Yarmush ML, Parekkadan B

Implantable microenvironments to attract hematopoietic stem/cancer cells. Proc Natl Acad Sci U S A. 2012;109(48):19638-43 - PMID: 23150542 - PMCID: PMC3511730 - DOI: 10.1073/pnas.1208384109

Kastrup CJ, Nahrendorf M, Figueiredo JL, Lee H, Kambhampati S, Lee T, Cho SW, Gorbatov R, Iwamoto Y, Dang TT, Dutta P, Yeon JH, Cheng H, Pritchard CD, Vegas AJ, Siegel CD, Macdougall S, Okonkwo M, Thai A, Stone JR, Coury AJ, Weissleder R, Langer R, Anderson DG

Painting blood vessels and atherosclerotic plaques with an adhesive drug depot. Proc Natl Acad Sci U S A. 2012;109(52):21444-9 - PMID: 23236189 - PMCID: PMC3535589 - DOI: 10.1073/pnas.1217972110

Liu Y, Shoji-Kawata S, Sumpter RM, Wei Y, Ginet V, Zhang L, Posner B, Tran KA, Green DR, Xavier RJ, Shaw SY, Clarke PG, Puyal J, Levine B

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia. Proc Natl Acad Sci U S A. 2013;110(51):20364-71 - PMID: 24277826 - PMCID: PMC3870705 - DOI: 10.1073/pnas.1319661110

Peterson VM*, Castro CM*, Chung J, Miller NC, Ullal AV, Castano MD, Penson RT, Lee H, Birrer MJ, Weissleder R

Ascites analysis by a microfluidic chip allows tumor-cell profiling Proc Natl Acad Sci U S A. 2013;110(51):E4978-86 - PMID: 24297935 - PMCID: PMC3870756 - DOI: 10.1073/pnas.1315370110

Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos JA, Weng Z, White KP, Hardison RC

Defining functional DNA elements in the human genome. Proc Natl Acad Sci U S A. 2014;111(17):6131-6138 - PMID: 24753594 - PMCID: PMC4035993 - DOI: 10.1073/pnas.1318948111

Morton AM, Sefik E, Upadhyay R, Weissleder R, Benoist C, Mathis D

Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut. Proc Natl Acad Sci U S A. 2014;111(18):6696-701 - PMID: 24753589 - PMCID: PMC4020091 - DOI: 10.1073/pnas.1405634111

Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D

Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature. Proc Natl Acad Sci U S A. 2014;111(31):11419-24 - PMID: 25049388 - PMCID: PMC4128122 - DOI: 10.1073/pnas.1410854111

Aguirre AD, Vinegoni C, Sebas M, Weissleder R

Intravital imaging of cardiac function at the single-cell level. Proc Natl Acad Sci U S A. 2014;111(31):11257-62 - PMID: 25053815 - PMCID: PMC4128110 - DOI: 10.1073/pnas.1401316111

Kellis M, Wold B, Snyder MP, Bernstein BE, Kundaje A, Marinov GK, Ward LD, Birney E, Crawford GE, Dekker J, Dunham I, Elnitski LL, Farnham PJ, Feingold EA, Gerstein M, Giddings MC, Gilbert DM, Gingeras TR, Green ED, Guigo R, Hubbard T, Kent J, Lieb JD, Myers RM, Pazin MJ, Ren B, Stamatoyannopoulos J, Weng Z, White KP, Hardison RC

Reply to Brunet and Doolittle: Both selected effect and causal role elements can influence human biology and disease. Proc Natl Acad Sci U S A. 2014;111(33):E3366 - PMID: 25275169 - PMCID: PMC4143047 - DOI: 10.1073/pnas.1410434111

Yashiro-Ohtani Y, Wang H, Zang C, Arnett KL, Bailis W, Ho Y, Knoechel B, Lanauze C, Louis L, Forsyth KS, Chen S, Chung Y, Schug J, Blobel GA, Liebhaber SA, Bernstein BE, Blacklow SC, Liu XS, Aster JC, Pear WS

Long-range enhancer activity determines Myc sensitivity to Notch inhibitors in T cell leukemia. Proc Natl Acad Sci U S A. 2014;111(46):E4946-53 - PMID: 25369933 - PMCID: PMC4246292 - DOI: 10.1073/pnas.1407079111

Magnuson AM, Thurber GM, Kohler RH, Weissleder R, Mathis D, Benoist C

Population dynamics of islet-infiltrating cells in autoimmune diabetes. Proc Natl Acad Sci U S A. 2015;112(5):1511-6 - PMID: 25605891 - PMCID: PMC4321317 - DOI: 10.1073/pnas.1423769112

Gaglia JL, Harisinghani M, Aganj I, Wojtkiewicz GR, Hedgire S, Benoist C Mathis D, Weissleder R

Noninvasive mapping of pancreatic inflammation in recent-onset type-1 diabetes patients Proc Natl Acad Sci U S A. 2015;112(7):2139-44 - PMID: 25650428 - PMCID: PMC4343112 - DOI: 10.1073/pnas.1424993112

Im H, Castro CM, Shao H, Liong M, Song J, Pathania D, Fexon L, Min C, Avila-Wallace M, Zurkiya O, Rho J, Magaoay B, Tambouret RH, Pivovarov M, Weissleder R*, Lee H*

Digital diffraction analysis enables low-cost molecular diagnostics on a smartphone Proc Natl Acad Sci U S A. 2015;112(18):5613-8 - PMID: 25870273 - PMCID: PMC4426451 - DOI: 10.1073/pnas.1501815112

Rashidian M, Keliher EJ, Bilate AM, Duarte JN, Wojtkiewicz GR, Jacobsen JT, Cragnolini J, Swee LK, Victora GD, Weissleder R, Ploegh HL

Noninvasive imaging of immune responses. Proc Natl Acad Sci U S A. 2015;112(19):6146-51 - PMID: 25902531 - PMCID: PMC4434737 - DOI: 10.1073/pnas.1502609112

Di Caprio G, Stokes C, Higgins JM, Schonbrun E

Single-cell measurement of red blood cell oxygen affinity. Proc Natl Acad Sci U S A. 2015;112(32):9984-9 - PMID: 26216973 - PMCID: PMC4538663 - DOI: 10.1073/pnas.1509252112

Pépin D, Sosulski A, Zhang L, Wang D, Vathipadiekal V, Hendren K, Coletti CM, Yu A, Castro CM, Birrer MJ, Gao G, Donahoe PK

AAV9 delivering a modified human Mullerian inhibiting substance as a gene therapy in patient-derived xenografts of ovarian cancer. Proc Natl Acad Sci U S A. 2015;112(32):E4418-27 - PMID: 26216943 - PMCID: PMC4538667 - DOI: 10.1073/pnas.1510604112

Weissleder R, Nahrendorf M

Advancing biomedical imaging Proc Natl Acad Sci U S A. 2015;112(47):14424-8 - PMID: 26598657 - PMCID: PMC4664297 - DOI: 10.1073/pnas.1508524112

Ramasamy S, Saez B, Mukhopadhyay S, Ding D, Ahmed AM, Chen X, Pucci F, Yamin R, Wang J, Pittet MJ, Kelleher CM, Scadden DT, Sweetser DA

Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway. Proc Natl Acad Sci U S A. 2016;113(7):1871-6 - PMID: 26831087 - PMCID: PMC4763742 - DOI: 10.1073/pnas.1511380113

Hosseini P, Abidi SZ, Du E, Papageorgiou DP, Choi Y, Park Y, Higgins JM, Kato GJ, Suresh S, Dao M, Yaqoob Z, So PT

Cellular normoxic biophysical markers of hydroxyurea treatment in sickle cell disease. Proc Natl Acad Sci U S A. 2016;113(34):9527-32 - PMID: 27512047 - PMCID: PMC5003247 - DOI: 10.1073/pnas.1610435113

Hideshima T, Qi J, Paranal RM, Tang W, Greenberg E, West N, Colling ME, Estiu G, Mazitschek R, Perry JA, Ohguchi H, Cottini F, Mimura N, Görgün G, Tai YT, Richardson PG, Carrasco RD, Wiest O, Schreiber SL, Anderson KC, Bradner JE

Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma. Proc Natl Acad Sci U S A. 2016;113(46):13162-13167 - PMID: 27799547 - PMCID: PMC5135369 - DOI: 10.1073/pnas.1608067113

Kirschbaum K, Sonner JK, Zeller MW, Deumelandt K, Bode J, Sharma R, Krüwel T, Fischer M, Hoffmann A, Costa da Silva M, Muckenthaler MU, Wick W, Tews B, Chen JW, Heiland S, Bendszus M, Platten M, Breckwoldt MO

In vivo nanoparticle imaging of innate immune cells can serve as a marker of disease severity in a model of multiple sclerosis. Proc Natl Acad Sci U S A. 2016;113(46):13227-13232 - PMID: 27799546 - PMCID: PMC5135308 - DOI: 10.1073/pnas.1609397113

Tang J, Baxter S, Menon A, Alaarg A, Sanchez-Gaytan BL, Fay F, Zhao Y, Ouimet M, Braza MS, Longo VA, Abdel-Atti D, Duivenvoorden R, Calcagno C, Storm G, Tsimikas S, Moore KJ, Swirski FK, Nahrendorf M, Fisher EA, Pérez-Medina C, Fayad ZA, Reiner T, Mulder WJ

Immune cell screening of a nanoparticle library improves atherosclerosis therapy. Proc Natl Acad Sci U S A. 2016;113(44):E6731-E6740 - PMID: 27791119 - PMCID: PMC5098679 - DOI: 10.1073/pnas.1609629113

Grossman SR, Zhang X, Wang L, Engreitz J, Melnikov A, Rogov P, Tewhey R, Isakova A, Deplancke B, Bernstein BE, Mikkelsen TS, Lander ES

Systematic dissection of genomic features determining transcription factor binding and enhancer function. Proc Natl Acad Sci U S A. 2017;114(7):E1291-E1300 - PMID: 28137873 - PMCID: PMC5321001 - DOI: 10.1073/pnas.1621150114

Miller MA, Meyer AS, Beste MT, Lasisi Z, Reddy S, Jeng KW, Chen CH, Han J, Isaacson K, Griffith LG, Lauffenburger DA

ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling. Proc Natl Acad Sci U S A. 2013;110(22):E2074-83 - PMID: 23674691 - PMCID: PMC3670354 - DOI: 10.1073/pnas.1222387110

Dang M, Armbruster N, Miller MA, Cermeno E, Hartmann M, Bell GW, Root DE, Lauffenburger DA, Lodish HF, Herrlich A

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways. Proc Natl Acad Sci U S A. 2013;110(24):9776-81 - PMID: 23720309 - PMCID: PMC3683718 - DOI: 10.1073/pnas.1307478110

Mohan JF, Kohler RH, Hill JA, Weissleder R, Mathis D, Benoist C

Imaging the emergence and natural progression of spontaneous autoimmune diabetes. Proc Natl Acad Sci U S A. 2017;114(37):E7776-E7785 - PMID: 28839093 - PMCID: PMC5604023 - DOI: 10.1073/pnas.1707381114

He Q, Bouley R, Liu Z, Wein MN, Zhu Y, Spatz JM, Wang CY, Divieti Pajevic P, Plagge A, Babitt JL, Bastepe M

Large G protein α-subunit XLαs limits clathrin-mediated endocytosis and regulates tissue iron levels in vivo. Proc Natl Acad Sci U S A. 2017;114(45):E9559-E9568 - PMID: 29078380 - PMCID: PMC5692581 - DOI: 10.1073/pnas.1712670114

Chaudhury A, Noiret L, Higgins JM

White blood cell population dynamics for risk stratification of acute coronary syndrome. Proc Natl Acad Sci U S A. 2017;114(46):12344-12349 - PMID: 29087321 - PMCID: PMC5699055 - DOI: 10.1073/pnas.1709228114

Chen L, Lee JW, Chou CL, Nair AV, Battistone MA, Păunescu TG, Merkulova M, Breton S, Verlander JW, Wall SM, Brown D, Burg MB, Knepper MA

Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq. Proc Natl Acad Sci U S A. 2017;114(46):E9989-E9998 - PMID: 29089413 - PMCID: PMC5699061 - DOI: 10.1073/pnas.1710964114

Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I

Stress granule-associated protein G3BP2 regulates breast tumor initiation. Proc Natl Acad Sci U S A. 2017;114(5):1033-1038 - PMID: 28096337 - PMCID: PMC5293063 - DOI: 10.1073/pnas.1525387114

Naxerova K, Brachtel E, Salk JJ, Seese AM, Power K, Abbasi B, Snuderl M, Chiang S, Kasif S, Jain RK

Hypermutable DNA chronicles the evolution of human colon cancer. Proc Natl Acad Sci U S A. 2014;111(18):E1889-98 - PMID: 24753616 - PMCID: PMC4020055 - DOI: 10.1073/pnas.1400179111

Liu J, Liao S, Diop-Frimpong B, Chen W, Goel S, Naxerova K, Ancukiewicz M, Boucher Y, Jain RK, Xu L

TGF-β blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma. Proc Natl Acad Sci U S A. 2012;109(41):16618-23 - PMID: 22996328 - PMCID: PMC3478596 - DOI: 10.1073/pnas.1117610109

Chen L, Lee JW, Chou CL, Nair AV, Battistone MA, Păunescu TG, Merkulova M, Breton S, Verlander JW, Wall SM, Brown D, Burg MB, Knepper MA

Reply to Edemir: Physiological regulation and single-cell RNA sequencing. Proc Natl Acad Sci U S A. 2018;115(3):E351-E352 - PMID: 29311339 - PMCID: PMC5777009 - DOI: 10.1073/pnas.1720333115

Ingram JR, Blomberg OS, Rashidian M, Ali L, Garforth S, Fedorov E, Fedorov AA, Bonanno JB, Le Gall C, Crowley S, Espinosa C, Biary T, Keliher EJ, Weissleder R, Almo SC, Dougan SK, Ploegh HL, Dougan M

Anti-CTLA-4 therapy requires an Fc domain for efficacy. Proc Natl Acad Sci U S A. 2018;115(15):3912-3917 - PMID: 29581255 - PMCID: PMC5899492 - DOI: 10.1073/pnas.1801524115

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT, Barker FG, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP

Genotype-targeted local therapy of glioma. Proc Natl Acad Sci U S A. 2018;115(36):E8388-E8394 - PMID: 30082399 - PMCID: PMC6130372 - DOI: 10.1073/pnas.1805751115

Magnuson AM, Kiner E, Ergun A, Park JS, Asinovski N, Ortiz-Lopez A, Kilcoyne A, Paoluzzi-Tomada E, Weissleder R, Mathis D, Benoist C

Identification and validation of a tumor-infiltrating Treg transcriptional signature conserved across species and tumor types. Proc Natl Acad Sci U S A. 2018;115(45):E10672-E10681 - PMID: 30348759 - PMCID: PMC6233093 - DOI: 10.1073/pnas.1810580115

Pineda JJ, Miller MA, Song Y, Kuhn H, Mikula H, Tallapragada N, Weissleder R, Mitchison TJ

Site occupancy calibration of taxane pharmacology in live cells and tissues Proc Natl Acad Sci U S A. 2018;115(48):E11406-E11414 - PMID: 30429313 - PMCID: PMC6275538 - DOI: 10.1073/pnas.1800047115

Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy. Proc Natl Acad Sci U S A. 2019;116(22):10674-10680 - PMID: 31040208 - PMCID: PMC6561160 - DOI: 10.1073/pnas.1819889116

Florian S, Iwamoto Y, Coughlin M, Weissleder R, Mitchison TJ

A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor Proc Natl Acad Sci U S A. 2019;116(23):11444-11453 - PMID: 31101720 - PMCID: PMC6561274 - DOI: 10.1073/pnas.1702372116

Wang C, Keliher E, Zeller MWG, Wojtkiewicz GR, Aguirre AD, Buckbinder L, Kim HY, Chen J, Maresca K, Ahmed MS, Motlagh NJ, Nahrendorf M, Chen JW

An activatable PET imaging radioprobe is a dynamic reporter of myeloperoxidase activity in vivo. Proc Natl Acad Sci U S A. 2019;116(24):11966-11971 - PMID: 31123149 - PMCID: PMC6575581 - DOI: 10.1073/pnas.1818434116

Babitt JL

Ironing out pulmonary arterial hypertension. Proc Natl Acad Sci U S A. 2019;116(26):12604-12606 - PMID: 31171658 - PMCID: PMC6601273 - DOI: 10.1073/pnas.1908298116

Heyde A, Reiter JG, Naxerova K, Nowak MA

Consecutive seeding and transfer of genetic diversity in metastasis. Proc Natl Acad Sci U S A. 2019;116(28):14129-14137 - PMID: 31239334 - PMCID: PMC6628640 - DOI: 10.1073/pnas.1819408116

Di Caprio G*, Schonbrun E*, Gonçalves BP, Valdez JM, Wood DK, Higgins JM

High-throughput assessment of hemoglobin polymer in single red blood cells from sickle cell patients under controlled oxygen tension. Proc Natl Acad Sci U S A. 2019;116(50):25236-25242 - PMID: 31767751 - PMCID: PMC6911208 - DOI: 10.1073/pnas.1914056116

Kim Y, Sundrud MS, Zhou C, Edenius M, Zocco D, Powers K, Zhang M, Mazitschek R, Rao A, Yeo CY, Noss EH, Brenner MB, Whitman M, Keller TL

Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. Proc Natl Acad Sci U S A. 2020;117(16):8900-8911 - PMID: 32253314 - PMCID: PMC7183223 - DOI: 10.1073/pnas.1913788117

Chen IX, Newcomer K, Pauken KE, Juneja VR, Naxerova K, Wu MW, Pinter M, Sen DR, Singer M, Sharpe AH, Jain RK

A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade. Proc Natl Acad Sci U S A. 2020;117(38):23684-23694 - PMID: 32907939 - PMCID: PMC7519254 - DOI: 10.1073/pnas.2002806117

Zaidman NA, Tomilin VN, Hassanzadeh Khayyat N, Damarla M, Tidmore J, Capen DE, Brown D, Pochynyuk OM, Pluznick JL

Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion. Proc Natl Acad Sci U S A. 2020;117(42):26470-26481 - PMID: 33004624 - PMCID: PMC7584995 - DOI: 10.1073/pnas.2007620117

Zhang Y, Kohrn BF, Yang M, Nachmanson D, Soong TR, Lee IH, Tao Y, Clevers H, Swisher EM, Brentnall TA, Loeb LA, Kennedy SR, Salk JJ, Naxerova K, Risques RA

PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage. Proc Natl Acad Sci U S A. 2021;118(31):ePub - PMID: 34330826 - PMCID: PMC8346827 - DOI: 10.1073/pnas.2023373118

Wang J, Jalali Motlagh N, Wang C, Wojtkiewicz GR, Schmidt S, Chau C, Narsimhan R, Kullenberg EG, Zhu C, Linnoila J, Yao Z, Chen JW

d-mannose suppresses oxidative response and blocks phagocytosis in experimental neuroinflammation. Proc Natl Acad Sci U S A. 2021;118(44):ePub - PMID: 34702739 - PMCID: PMC8673064 - DOI: 10.1073/pnas.2107663118

Ho WW, Gomes-Santos IL, Aoki S, Datta M, Kawaguchi K, Talele NP, Roberge S, Ren J, Liu H, Chen IX, Andersson P, Chatterjee S, Kumar AS, Amoozgar Z, Zhang Q, Huang P, Ng MR, Chauhan VP, Xu L, Duda DG, Clark JW, Pittet MJ, Fukumura D, Jain RK

Dendritic cell paucity in mismatch repair-proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy. Proc Natl Acad Sci U S A. 2021;118(45):ePub - PMID: 34725151 - PMCID: PMC8609309 - DOI: 10.1073/pnas.2105323118

Datta M, Chatterjee S, Perez EM, Gritsch S, Roberge S, Duquette M, Chen IX, Naxerova K, Kumar AS, Ghosh M, Emblem KE, Ng MR, Ho WW, Kumar P, Krishnan S, Dong X, Speranza MC, Neagu MR, Iorgulescu JB, Huang RY, Youssef G, Reardon DA, Sharpe AH, Freeman GJ, Suvà ML, Xu L, Jain RK

Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models. Proc Natl Acad Sci U S A. 2023;120(6):e2219199120 - PMID: 36724255 - PMCID: PMC9963691 - DOI: 10.1073/pnas.2219199120

Qiang Y, Sissoko A, Liu ZL, Dong T, Zheng F, Kong F, Higgins JM, Karniadakis GE, Buffet PA, Suresh S, Dao M

Microfluidic study of retention and elimination of abnormal red blood cells by human spleen with implications for sickle cell disease. Proc Natl Acad Sci U S A. 2023;120(6):e2217607120 - PMID: 36730189 - PMCID: PMC9963977 - DOI: 10.1073/pnas.2217607120

Lutz EA, Agarwal Y, Momin N, Cowles SC, Palmeri JR, Duong E, Hornet V, Sheen A, Lax BM, Rothschilds AM, Irvine DJ, Spranger S, Wittrup KD

Alum-anchored intratumoral retention improves the tolerability and antitumor efficacy of type I interferon therapies. Proc Natl Acad Sci U S A. 2022;119(36):e2205983119 - PMID: 36037341 - PMCID: PMC9457244 - DOI: 10.1073/pnas.2205983119

Aldawood ZA, Mancinelli L, Geng X, Yeh SA, Di Carlo R, C Leite T, Gustafson J, Wilk K, Yozgatian J, Garakani S, Bassir SH, Cunningham ML, Lin CP, Intini G

Expansion of the sagittal suture induces proliferation of skeletal stem cells and sustains endogenous calvarial bone regeneration. Proc Natl Acad Sci U S A. 2023;120(16):e2120826120 - PMID: 37040407 - PMCID: PMC10120053 - DOI: 10.1073/pnas.2120826120

Lau KS, Cortez-Retamozo V, Philips SR, Pittet MJ, Lauffenburger DA, Haigis KM

Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium PLoS Biol. 2012;10(9):e1001393 - PMID: 23055830 - PMCID: PMC3463506 - DOI: 10.1371/journal.pbio.1001393

Kelloff GJ, Krohn KA, Larson SM, Weissleder R, Mankoff DA, Hoffman JM, Link JM, Guyton KZ, Eckelman WC, Scher HI, O

The progress and promise of molecular imaging probes in oncologic drug development. Clin Cancer Res. 2005;11(22):7967-85 - PMID: 16299226 - DOI: 10.1158/1078-0432.CCR-05-1302

Ayyoub M, Zippelius A, Pittet M, Rimoldi D, Valmori D, Cerottini J, Romero P, Lejeune F, Lienard D, Speiser D

Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1. Clin Cancer Res. 2003;9:669-77 - PMID: 12576434

Pittet M, Speiser D, Lienard D, Valmori D, Guillaume P, Dutoit V, Rimoldi D, Lejeune F, Cerottini J, Romero P

Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide. Clin Cancer Res. 2001;7:796s-803s - PMID: 11300475

Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK

Regression of drug-resistant lung cancer by the combination of rosiglitazone and Carboplatin. Clin Cancer Res. 2008;14(20):6478-86 - PMID: 18927287 - PMCID: PMC2696122 - DOI: 10.1158/1078-0432.CCR-08-1128

Kleijn A*, Chen JW*, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G

Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clin Cancer Res. 2011;17(13):4484-93 - PMID: 21558403 - PMCID: PMC3131449 - DOI: 10.1158/1078-0432.CCR-11-0575

Bazzaro M, Lin Z, Santillan A, Lee MK, Wang MC, Chan KC, Bristow RE, Mazitschek R, Bradner J, Roden RB

Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor. Clin Cancer Res. 2008;14(22):7340-7 - PMID: 19010849 - PMCID: PMC2744414 - DOI: 10.1158/1078-0432.CCR-08-0642

Pucci F, Pittet MJ

Molecular Pathways: Tumor-derived microvesicles and their interactions with immune cells in vivo. Clin Cancer Res. 2013;19(10):2598-604 - PMID: 23426276 - PMCID: PMC3655093 - DOI: 10.1158/1078-0432.CCR-12-0962

Alagesan B, Contino G, Guimaraes AR, Corcoran RB, Desphande V, Wojtkiewicz GR, Hezel AF, Wong KK, Loda M, Weissleder R, Benes CH, Engelman JA, Bardeesy N

Combined MEK and PI3K inhibition in a mouse model of pancreatic cancer. Clin Cancer Res. 2014;21(2):396-404 - PMID: 25348516 - PMCID: PMC4447091 - DOI: 10.1158/1078-0432.CCR-14-1591

Gainor JF, Shaw AT, Sequist LV, Fu X, Azzoli CG, Piotrowska Z, Huynh TG, Zhao L, Fulton L, Schultz K, Howe E, Farago AF, Sullivan RJ, Stone JR, Digumarthy S, Moran T, Hata AN, Yagi Y, Yeap BY, Engelman JA, Mino-Kenudson M

EGFR Mutations and ALK Rearrangements Are Associated with Low Response Rates to PD-1 Pathway Blockade in Non-Small Cell Lung Cancer (NSCLC): A Retrospective Analysis. Clin Cancer Res. 2016;22(18):4585-93 - PMID: 27225694 - PMCID: PMC5026567 - DOI: 10.1158/1078-0432.CCR-15-3101

Miller MA, Sullivan RJ, Lauffenburger DA

Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer. Clin Cancer Res. 2016;23(3):623-629 - PMID: 27895032 - PMCID: PMC5290119 - DOI: 10.1158/1078-0432.CCR-16-0869

Song KA, Niederst MJ, Lochmann TL, Hata AN, Kitai H, Ham J, Floros KV, Hicks MA, Hu H, Mulvey HE, Drier Y, Heisey DAR, Hughes MT, Patel NU, Lockerman E, Garcia AR, Gillepsie S, Archibald HL, Gomez-Caraballo M, Nulton TJ, Windle B, Piotrowska Z, Sahingur SE, Taylor SM, Dozmorov MG, Sequist LV, Bernstein BE, Ebi H, Engelman JA, Faber AC

Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM. Clin Cancer Res. 2017;24(1):197-208 - PMID: 29051323 - PMCID: PMC5959009 - DOI: 10.1158/1078-0432.CCR-17-1577

Liu H, Naxerova K, Pinter M, Incio J, Lee H, Shigeta K, Ho WW, Crain JA, Jacobson A, Michelakos T, Dias-Santos D, Zanconato A, Hong TS, Clark JW, Murphy JE, Ryan DP, Deshpande V, Lillemoe KD, Fernandez-Del Castillo C, Downes M, Evans RM, Michaelson J, Ferrone CR, Boucher Y, Jain RK

Use of Angiotensin System Inhibitors Is Associated with Immune Activation and Longer Survival in Nonmetastatic Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2017;23(19):5959-5969 - PMID: 28600474 - PMCID: PMC5856249 - DOI: 10.1158/1078-0432.CCR-17-0256

Liu J, Liao S, Huang Y, Samuel R, Shi T, Naxerova K, Huang P, Kamoun W, Jain RK, Fukumura D, Xu L

PDGF-D improves drug delivery and efficacy via vascular normalization, but promotes lymphatic metastasis by activating CXCR4 in breast cancer. Clin Cancer Res. 2011;17(11):3638-48 - PMID: 21459800 - PMCID: PMC3107920 - DOI: 10.1158/1078-0432.CCR-10-2456

Ippen FM, Alvarez-Breckenridge CA, Kuter BM, Fink AL, Bihun IV, Lastrapes M, Penson T, Schmidt SP, Wojtkiewicz GR, Ning J, Subramanian M, Giobbie-Hurder A, Martinez-Lage M, Carter SL, Cahill DP, Wakimoto H, Brastianos PK

The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA-Mutant Breast Cancer Brain Metastases. Clin Cancer Res. 2019;25(11):3374-3383 - PMID: 30796030 - PMCID: PMC6685218 - DOI: 10.1158/1078-0432.CCR-18-3049

Algazi AP, Twitty CG, Tsai KK, Le M, Pierce R, Browning E, Hermiz R, Canton DA, Bannavong D, Oglesby A, Francisco M, Fong L, Pittet MJ, Arlauckas SP, Garris C, Levine LP, Bifulco C, Ballesteros-Merino C, Bhatia S, Gargosky S, Andtbacka RHI, Fox BA, Rosenblum MD, Daud AI

Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma. Clin Cancer Res. 2020;26(12):2827-2837 - PMID: 32376655 - PMCID: PMC9354653 - DOI: 10.1158/1078-0432.CCR-19-2217

Muralidharan K, Yekula A, Small JL, Rosh ZS, Kang KM, Wang L, Lau S, Zheng H, Lee H, Bettegowda C, Chicoine MR, Kalkanis S, Shankar GM, Nahed BV, Curry WT, Jones PS, Cahill DP, Balaj L, Carter BS

TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas. Clin Cancer Res. 2020;27(1):169-178 - PMID: 33051308 - PMCID: PMC7785705 - DOI: 10.1158/1078-0432.CCR-20-3083

Wu CY, Yang LH, Yang HY, Knoff J, Peng S, Lin YH, Wang C, Alvarez RD, Pai SI, Roden RB, Hung CF, Wu TC

Enhanced cancer radiotherapy through immunosuppressive stromal cell destruction in tumors. Clin Cancer Res. 2013;20(3):644-57 - PMID: 24300786 - PMCID: PMC3946442 - DOI: 10.1158/1078-0432.CCR-13-1334

Chuang CM, Monie A, Wu A, Pai SI, Hung CF

Combination of viral oncolysis and tumor-specific immunity to control established tumors. Clin Cancer Res. 2009;15(14):4581-8 - PMID: 19584165 - PMCID: PMC3076709 - DOI: 10.1158/1078-0432.CCR-08-2685

Ha PK, Pai SI, Westra WH, Gillison ML, Tong BC, Sidransky D, Califano JA

Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res. 2002;8(5):1203-9 - PMID: 12006539

Capone RB, Pai SI, Koch WM, Gillison ML, Danish HN, Westra WH, Daniel R, Shah KV, Sidransky D

Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma. Clin Cancer Res. 2000;6(11):4171-5 - PMID: 11106228

Garris CS, Luke JJ

Dendritic Cells, the T-cell-inflamed Tumor Microenvironment, and Immunotherapy Treatment Response. Clin Cancer Res. 2020;26(15):3901-3907 - PMID: 32332013 - PMCID: PMC7607412 - DOI: 10.1158/1078-0432.CCR-19-1321

Oh J, Carlson JCT, Landeros C, Lee H, Ferguson S, Faquin WC, Clark JR, Pittet MJ, Pai SI, Weissleder R

Rapid serial immunoprofiling of the tumor immune microenvironment by fine needle sampling Clin Cancer Res. 2021;27(17):4781-4793 - PMID: 34233961 - PMCID: PMC8416923 - DOI: 10.1158/1078-0432.CCR-21-1252

Guo JA, Hoffman HI, Weekes CD, Zheng L, Ting DT, Hwang WL

Refining the Molecular Framework for Pancreatic Cancer with Single-cell and Spatial Technologies. Clin Cancer Res. 2021;27(14):3825-3833 - PMID: 33653818 - PMCID: PMC8282742 - DOI: 10.1158/1078-0432.CCR-20-4712

Guo JA, Hoffman HI, Shroff SG, Chen P, Hwang PG, Kim DY, Kim DW, Cheng SW, Zhao D, Mahal BA, Alshalalfa M, Niemierko A, Wo JY, Loeffler JS, Fernandez-Del Castillo C, Jacks T, Aguirre AJ, Hong TS, Mino-Kenudson M, Hwang WL

Pan-cancer Transcriptomic Predictors of Perineural Invasion Improve Occult Histopathologic Detection. Clin Cancer Res. 2021;27(10):2807-2815 - PMID: 33632928 - PMCID: PMC8127360 - DOI: 10.1158/1078-0432.CCR-20-4382

Hu H, Ng TSC, Kang M, Scott E, Li R, Quintana JM, Matvey D, Vantaku VR, Weissleder R, Parangi S, Miller MA

Thyroid cancers exhibit oncogene-enhanced macropinocytosis that is restrained by IGF1R and promotes albumin-drug-conjugate response. Clin Cancer Res. 2023;29(17):3457-3470 - PMID: 37289199 - PMCID: PMC10527034 - DOI: 10.1158/1078-0432.CCR-22-2976

Pai SI, Faivre S, Licitra L, Machiels JP, Vermorken JB, Bruzzi P, Gruenwald V, Giglio RE, Leemans CR, Seiwert TY, Soulieres D

Comparative analysis of the phase III clinical trials of anti-PD1 monotherapy in head and neck squamous cell carcinoma patients (CheckMate 141 and KEYNOTE 040). J Immunother Cancer. 2019;7(1):96 - PMID: 30944020 - PMCID: PMC6446400 - DOI: 10.1186/s40425-019-0578-0

Gastman B, Agarwal PK, Berger A, Boland G, Broderick S, Butterfield LH, Byrd D, Fecci PE, Ferris RL, Fong Y, Goff SL, Grabowski MM, Ito F, Lim M, Lotze MT, Mahdi H, Malafa M, Morris CD, Murthy P, Neves RI, Odunsi A, Pai SI, Prabhakaran S, Rosenberg SA, Saoud R, Sethuraman J, Skitzki J, Slingluff CL, Sondak VK, Sunwoo JB, Turcotte S, Yeung CC, Kaufman HL

Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery Committee. J Immunother Cancer. 2020;8(2):ePub - PMID: 33199512 - PMCID: PMC7670953 - DOI: 10.1136/jitc-2020-001583

Clifton GT, Rothenberg M, Ascierto PA, Begley G, Cecchini M, Eder JP, Ghiringhelli F, Italiano A, Kochetkova M, Li R, Mechta-Grigoriou F, Pai SI, Provenzano P, Puré E, Ribas A, Schalper KA, Fridman WH

Developing a definition of immune exclusion in cancer: results of a modified Delphi workshop. J Immunother Cancer. 2023;11(6):ePub - PMID: 37290925 - PMCID: PMC10254706 - DOI: 10.1136/jitc-2023-006773

Shah K, Russinova E, Gadella T, Willemse J, De Vries S

The Arabidopsis kinase-associated protein phosphatase controls internalization of the somatic embryogenesis receptor kinase 1. Gene Dev. 2002;16(13):1707-20 - PMID: 12101128 - PMCID: PMC186368 - DOI: 10.1101/gad.220402

de Sousa Lopes S, Roelen B, Monteiro R, Emmens R, Lin HY, Li E, Lawson K, Mummery C

BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Gene Dev. 2004;18(15):1838-49 - PMID: 15289457 - PMCID: PMC517404 - DOI: 10.1101/gad.294004

Li G, Margueron R, Ku M, Chambon P, Bernstein BE, Reinberg D

Jarid2 and PRC2, partners in regulating gene expression. Gene Dev. 2010;24(4):368-80 - PMID: 20123894 - PMCID: PMC2816736 - DOI: 10.1101/gad.1886410

Peterson KA, Nishi Y, Ma W, Vedenko A, Shokri L, Zhang X, McFarlane M, Baizabal JM, Junker JP, van Oudenaarden A, Mikkelsen T, Bernstein BE, Bailey TL, Bulyk ML, Wong WH, McMahon AP

Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning. Gene Dev. 2012;26(24):2802-16 - PMID: 23249739 - PMCID: PMC3533082 - DOI: 10.1101/gad.207142.112

Koch PD, Quintana J, Ahmed MS, Kohler RH, Weissleder R

Small Molecule Imaging Agent for Mutant KRAS G12C Advanced Therapeutics. 2021;:2000290 - DOI: 10.1002/adtp.202000290

Shao H, Min C, Issadore D, Liong M, Yoon TJ, Weissleder R, Lee H

Magnetic Nanoparticles and microNMR for Diagnostic Applications. Theranostics. 2012;2(1):55-65 - PMID: 22272219 - PMCID: PMC3263516 - DOI: 10.7150/thno.3465

Shan G, Weissleder R, Hilderbrand SA

Upconverting Organic Dye Doped Core-Shell Nano-Composites for Dual-Modality NIR Imaging and Photo-Thermal Therapy. Theranostics. 2013;3(4):267-74 - PMID: 23606913 - PMCID: PMC3630527 - DOI: 10.7150/thno.5226

Wildgruber M, Swirski FK, Zernecke A

Molecular Imaging of Inflammation in Atherosclerosis. Theranostics. 2013;3(11):865-884 - PMID: 24312156 - PMCID: PMC3841337 - DOI: 10.7150/thno.5771

Yoon YI, Kwon YS, Cho HS, Heo SH, Park KS, Park SG, Lee SH, Hwang SI, Kim YI, Jae HJ, Ahn GJ, Cho YS, Lee H*, Lee HJ*, Yoon TJ*

Ultrasound-Mediated Gene and Drug Delivery Using a Microbubble-Liposome Particle System Theranostics. 2014;4(11):1133-1144

Turetsky A, Lee K, Song J, Giedt RJ, Kim E, Kovach AE, Hochberg EP, Castro CM, Lee H, Weissleder R

On chip analysis of CNS lymphoma in cerebrospinal fluid. Theranostics. 2015;5(8):796-804 - PMID: 26000053 - PMCID: PMC4440438 - DOI: 10.7150/thno.11220

Kim JY, Ryu JH, Schellingerhout D, Sun IC, Lee SK, Jeon S, Kim J, Kwon IC, Nahrendorf M, Ahn CH, Kim K, Kim DE

Direct Imaging of Cerebral Thromboemboli Using Computed Tomography and Fibrin-targeted Gold Nanoparticles. Theranostics. 2015;5(10):1098-114 - PMID: 26199648 - PMCID: PMC4508499 - DOI: 10.7150/thno.11679

Stein-Merlob AF, Kessinger CW, Erdem SS, Zelada H, Hilderbrand SA, Lin CP, Tearney GJ, Jaff MR, Reed GL, Henke PK, McCarthy JR, Jaffer FA

Blood Accessibility to Fibrin in Venous Thrombosis is Thrombus Age-Dependent and Predicts Fibrinolytic Efficacy: An In Vivo Fibrin Molecular Imaging Study. Theranostics. 2015;5(12):1317-27 - PMID: 26516370 - PMCID: PMC4615735 - DOI: 10.7150/thno.12494

Pathania D*, Im H*, Kilcoyne A, Sohani AR, Fexon L, Pivovarov M, Abramson JS, Randall TC, Chabner BA, Weissleder R, Lee H, Castro CM

Holographic Assessment of Lymphoma Tissue (HALT) for Global Oncology Field Applications Theranostics. 2016;6(10):1603-10 - PMID: 27446494 - PMCID: PMC4955059 - DOI: 10.7150/thno.15534

Mikula H, Stapleton S, Kohler RH, Vinegoni C, Weissleder R

Design and Development of Fluorescent Vemurafenib Analogs for In Vivo Imaging. Theranostics. 2017;7(5):1257-1265 - PMID: 28435463 - PMCID: PMC5399591 - DOI: 10.7150/thno.18238

Arlauckas SP*, Garren SB*, Garris CS, Kohler RH, Oh J, Pittet MJ, Weissleder R

Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages Theranostics. 2018;8(21):5842-5854 - PMID: 30613266 - PMCID: PMC6299430 - DOI: 10.7150/thno.26888

Ammari M, Presumey J, Ponsolles C, Roussignol G, Roubert C, Escriou V, Toupet K, Mausset-Bonnefont AL, Cren M, Robin M, Georgel P, Nehmar R, Taams L, Grün J, Grützkau A, Häupl T, Pers YM, Jorgensen C, Duroux-Richard I, Courties G, Apparailly F

Delivery of miR-146a to Ly6Chigh Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis. Theranostics. 2018;8(21):5972-5985 - PMID: 30613275 - PMCID: PMC6299444 - DOI: 10.7150/thno.29313

Bae SH, Jo A, Park JH, Lim CW, Choi Y, Oh J, Park JM, Kong T, Weissleder R, Lee H, Moon J

Bioassay for monitoring the anti-aging effect of cord blood treatment. Theranostics. 2019;9(1):1-10 - PMID: 30662549 - PMCID: PMC6332798 - DOI: 10.7150/thno.30422

Pathania D, Landeros C, Rohrer L, D’Agostino V, Hong S, Degani I, Avila-Wallace M, Pivovarov M, Randall T, Weissleder R, Lee H, Im H, Castro CM

Point-of-care cervical cancer screening using deep learning-based microholography Theranostics. 2019;9(26):8438-8447 - PMID: 31879529 - PMCID: PMC6924258 - DOI: 10.7150/thno.37187

Ng TSC, Garlin MA, Weissleder R, Miller MA

Understanding the EPR effect through image-guided systems pharmacology Theranostics. 2019;:ePub

Rodell CB, Ahmed MS, Garris CS, Pittet MJ, Weissleder R

Development of adamantane-conjugated TLR7/8 agonists for supramolecular delivery and cancer immunotherapy Theranostics. 2019;9(26):8426-8436 - PMID: 31879528 - PMCID: PMC6924259 - DOI: 10.7150/thno.35434

Rodell CB, Koch PD, Weissleder R

Screening for new macrophage therapeutics. Theranostics. 2019;9(25):7714-7729 - PMID: 31695796 - PMCID: PMC6831478 - DOI: 10.7150/thno.34421

Wang C, Pulli B, Jalali Motlagh N, Li A, Wojtkiewicz GR, Schmidt SP, Wu Y, Zeller MWG, Chen JW

A versatile imaging platform with fluorescence and CT imaging capabilities that detects myeloperoxidase activity and inflammation at different scales. Theranostics. 2019;9(25):7525-7536 - PMID: 31695784 - PMCID: PMC6831463 - DOI: 10.7150/thno.36264

Woo HK, Cho YK, Lee CY, Lee H, Castro CM, Lee H

Characterization and modulation of surface charges to enhance extracellular vesicle isolation in plasma. Theranostics. 2022;12(5):1988-1998 - PMID: 35265194 - PMCID: PMC8899565 - DOI: 10.7150/thno.69094 - Cover

Dosta P, Puigmal N, Cryer AM, Rodríguez AL, Scott E, Weissleder R, Miller MA, Artzi N

Polymeric microneedles enable simultaneous delivery of cancer immunomodulatory drugs and detection of skin biomarkers. Theranostics. 2023;13(1):1-15 - PMID: 36593949 - PMCID: PMC9800729 - DOI: 10.7150/thno.73966

Kim HS, Halabi EA, Enbergs N, Kohler RH, Fei F, Garris CS, Weissleder R

A non-lipid nucleic acid delivery vector with dendritic cell tropism and stimulation. Theranostics. 2024;14(7):2934-2945 - PMID: 38773971 - PMCID: PMC11103498 - DOI: 10.7150/thno.95267

Das R, Ge X, Fei F, Parvanian S, Weissleder R*, Garris CS*

Lipid Nanoparticle-mRNA Engineered Dendritic Cell Based Adoptive Cell Therapy Enhances Cancer Immune Response. Small Methods. 2024;9(1):e2400633 - PMID: 39039995 - PMCID: PMC11740962 - DOI: 10.1002/smtd.202400633

Wang C*, Jalali Motlagh N*, Wojtkiewicz GR, Yang H, Kim HH, Chen JW

A specific and adaptable approach to track CD206+ macrophages by molecular MRI and fluorescence imaging. Theranostics. 2025;15(3):1094-1109 - PMID: 39776805 - PMCID: PMC11700851 - DOI: 10.7150/thno.96488

Pittet M, Mempel T

Regulation of T Cell Migration and Effector Functions-Insights from in Vivo Imaging Studies Immunol Rev. 2007;:ePub

Pittet MJ, Mempel TR

Regulation of T-cell migration and effector functions: insights from in vivo imaging studies. Immunol Rev. 2008;221:107-29 - PMID: 18275478 - DOI: 10.1111/j.1600-065X.2008.00584.x

Romero P, Valmori D, Pittet M, Zippelius A, Rimoldi D, Levy F, Dutoit V, Ayyoub M, Rubio-Godoy V, Michielin O, Guillaume P, Batard P, Luescher I, Lejeune F, Lienard D, Rufer N, Dietrich P, Speiser D, Cerottini J

Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev. 2002;188:81-96 - PMID: 12445283 - DOI: 10.1034/j.1600-065x.2002.18808.x

Dutta P, Nahrendorf M

Regulation and consequences of monocytosis. Immunol Rev. 2014;262(1):167-78 - PMID: 25319334 - PMCID: PMC4203415 - DOI: 10.1111/imr.12219

Cheung PW, Bouley R, Brown D

Targeting the Trafficking of Kidney Water Channels for Therapeutic Benefit. Annu Rev Pharmacol Toxicol. 2019;60:175-194 - PMID: 31561739 - PMCID: PMC7334826 - DOI: 10.1146/annurev-pharmtox-010919-023654

Raju V, Reddy R, Javan AC, Hajihossainlou B, Weissleder R, Guiseppi-Elie A, Kurabayashi K, Jones SA, Faghih RT

Tracking inflammation status for improving patient prognosis: A review of current methods, unmet clinical needs and opportunities. Biotechnol Adv. 2025;82:108592 - PMID: 40324661 - PMCID: PMC12173025 - DOI: 10.1016/j.biotechadv.2025.108592

Perez JM, Simeone FJ, Tsourkas A, Josephson L, Weissleder R

Peroxidase substrate nanosensors for MR imaging Nano Lett. 0;4:119-122

McCarthy JR, Perez JM, Brueckner C, Weissleder R

Polymeric Nanoparticle Preparation that Eradicates Tumors. Nano Lett. 2005;5:2552-6 - PMID: 16351214 - DOI: 10.1021/nl0519229

Quinti L, Weissleder R, Tung CH

A Fluorescent Nanosensor for Apoptotic Cells Nano Lett. 2006;6 (3):488-490 - PMID: 16522048 - DOI: 10.1021/nl0524694

Lee H, Purdon AM, Chu V, Westervelt RM

Controlled Assembly of Magnetic Nanoparticles from Magnetotactic Bacteria Using Microelectromagnets Arrays Nano Lett. 0;4(5):995

Ghosh K, Kanapathipillai M, Korin N, McCarthy JR, Ingber D

Polymeric Nanomaterials for Islet Targeting and Immunotherapeutic Delivery. Nano Lett. 2011;12(1):203-8 - PMID: 22196766 - PMCID: PMC3280082 - DOI: 10.1021/nl203334c

Xu C, Miranda-Nieves D, Ankrum JA, Matthiesen ME, Phillips J, Roes I, Wojtkiewicz GR, Juneja V, Kultima JR, Zhao W, Vemula PK, Lin CP, Nahrendorf M, Karp JM

Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticle Loaded Poly(lactide-co-glycolide) Microparticles. Nano Lett. 2012;12(8):4131-9 - PMID: 22769232 - PMCID: PMC3552518 - DOI: 10.1021/nl301658q

Epa VC, Burden FR, Tassa C, Weissleder R, Shaw SY, Winkler DA

Modelling biological activities of nanoparticles. Nano Lett. 2012;12(11):5808-5812 - PMID: 23039907 - DOI: 10.1021/nl303144k

Im H, Bantz KC, Lindquist NC, Haynes CL, Oh SH

Vertically oriented sub-10-nm plasmonic nanogap arrays. Nano Lett. 2010;10(6):2231-6 - PMID: 20499849 - DOI: 10.1021/nl1012085

Ortiz-Orruño U, Jo A, Lee H, van Hulst NF, Liebel M

Precise Nanosizing with High Dynamic Range Holography. Nano Lett. 2020;21(1):317-322 - PMID: 33346670 - PMCID: PMC8326875 - DOI: 10.1021/acs.nanolett.0c03699

Nunes P, Ernandez T, Roth I, Qiao X, Strebel D, Bouley R, Charollais A, Ramadori P, Foti M, Meda P, Féraille E, Brown D, Hasler U

Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters. Autophagy. 2013;9(4):550-67 - PMID: 23380587 - PMCID: PMC3627670 - DOI: 10.4161/auto.23662

Corradini E, Meynard D, Wu Q, Chen S, Ventura P, Pietrangelo A, Babitt JL

Serum and liver iron differently regulate the bone morphogenetic protein 6 (BMP6)-SMAD signaling pathway in mice. Hepatology. 2011;54(1):273-84 - PMID: 21488083 - PMCID: PMC3277401 - DOI: 10.1002/hep.24359

Wang CY, Xiao X, Bayer A, Xu Y, Dev S, Canali S, Nair AV, Masia R, Babitt JL

Ablation of hepatocyte Smad1, Smad5 and Smad8 causes severe tissue iron loading and liver fibrosis in mice. Hepatology. 2019;70(6):1986-2002 - PMID: 31127639 - PMCID: PMC6874904 - DOI: 10.1002/hep.30780

Xiao X, Dev S, Canali S, Bayer A, Xu Y, Agarwal A, Wang CY, Babitt JL

Endothelial Bmp2 knockout exacerbates hemochromatosis in Hfe knockout mice but not Bmp6 knockout mice. Hepatology. 2020;72(2):642-655 - PMID: 31778583 - PMCID: PMC7253321 - DOI: 10.1002/hep.31048

Ferguson S, Yang KS, Weissleder R

Single extracellular vesicle analysis for early cancer detection Trends in Molecular Medicine. 2022;28(8):681-692 - PMID: 35624008 - PMCID: PMC9339504 - DOI: 10.1016/j.molmed.2022.05.003

Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg F, Weissleder R, Carson W, Chiocca A, Kaur B.

Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy J Natl Cancer Inst. 2007;(99) 23:1768-1781 - PMID: 18042934 - DOI: 10.1093/jnci/djm229

Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, Huang P, Fukumura D, Engelman JA, Jain RK

Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment. J Natl Cancer Inst. 2015;108(2):ePub - PMID: 26547932 - PMCID: PMC4862418 - DOI: 10.1093/jnci/djv313

Hwang WL, Wolfson RL, Niemierko A, Marcus KJ, DuBois SG, Haas-Kogan D

Clinical Impact of Tumor Mutational Burden in Neuroblastoma. J Natl Cancer Inst. 2019;111(7):695-699 - PMID: 30307503 - PMCID: PMC6624164 - DOI: 10.1093/jnci/djy157

Gupta S, Hanna PE, Ouyang T, Yamada KS, Sawtell R, Wang Q, Katz-Agranov N, Feghali L, Krasner CN, Bouberhan S, Castro CM, Sise ME

Kidney Function in Patients with Ovarian Cancer Treated with Poly (ADP-ribose) polymerase (PARP) Inhibitors. J Natl Cancer Inst. 2023;115(7):831-837 - PMID: 37074956 - PMCID: PMC10323894 - DOI: 10.1093/jnci/djad070

Batool SM, Yekula A, Khanna P, Hsia T, Gamblin AS, Ekanayake E, Escobedo AK, You DG, Castro CM, Im H, Kilic T, Garlin MA, Skog J, Dinulescu DM, Dudley J, Agrawal N, Cheng J, Abtin F, Aberle DR, Chia D, Elashoff D, Grognan T, Krysan K, Oh SS, Strom C, Tu M, Wei F, Xian RR, Skates SJ, Zhang DY, Trinh T, Watson M, Aft R, Rawal S, Agarwal A, Kesmodel SB, Yang C, Shen C, Hochberg FH, Wong DTW, Patel AA, Papadopoulos N, Bettegowda C, Cote RJ, Srivastava S, Lee H, Carter BS, Balaj L

The Liquid Biopsy Consortium: Challenges and opportunities for early cancer detection and monitoring. Cell Rep Med. 2023;4(10):101198 - PMID: 37716353 - PMCID: PMC10591039 - DOI: 10.1016/j.xcrm.2023.101198

Batool SM, Hsia T, Beecroft A, Lewis B, Ekanayake E, Rosenfeld Y, Escobedo AK, Gamblin AS, Rawal S, Cote RJ, Watson M, Wong DTW, Patel AA, Skog J, Papadopoulos N, Bettegowda C, Castro CM, Lee H, Srivastava S, Carter BS, Balaj L

Extrinsic and intrinsic preanalytical variables affecting liquid biopsy in cancer. Cell Rep Med. 2023;4(10):101196 - PMID: 37725979 - PMCID: PMC10591035 - DOI: 10.1016/j.xcrm.2023.101196

Oh J*, Hoelzl J*, Carlson JCT, Bill R, Peterson HM, Faquin WC, Pittet MJ, Pai SI, Weissleder R

Spatial analysis identifies DC niches as predictors of pembrolizumab therapy in head and neck squamous cell cancer Cell Rep Med. 2025;6(5):102100 - PMID: 40311615 - PMCID: PMC12147904 - DOI: 10.1016/j.xcrm.2025.102100

Kurata K, Bott AJ, Tye MA, Yamamoto L, Samur MK, Tai YT, Dunford J, Johansson C, Senbabaoglu F, Philpott M, Palmer C, Ramasamy K, Gooding S, Smilova M, Gaeta G, Guo M, Christianson JC, Payne NC, Singh K, Karagoz K, Stokes ME, Ortiz M, Hagner P, Thakurta A, Cribbs A, Mazitschek R, Hideshima T, Anderson KC, Oppermann U

Prolyl-tRNA synthetase as a novel therapeutic target in multiple myeloma. Blood Cancer J. 2023;13(1):12 - PMID: 36631435 - PMCID: PMC9834298 - DOI: 10.1038/s41408-023-00787-w

Mattoo H, Mahajan VS, Maehara T, Deshpande V, Della-Torre E, Wallace ZS, Kulikova M, Drijvers JM, Daccache J, Carruthers MN, Castellino F, Stone JR, Stone JH, Pillai S

Clonal expansion of CD4(+) cytotoxic T lymphocytes in patients with IgG4-related disease. J Allergy Clin Immunol. 2016;138(3):825-38 - PMID: 26971690 - PMCID: PMC5014627 - DOI: 10.1016/j.jaci.2015.12.1330

Park CO, Fu X, Jiang X, Pan Y, Teague JE, Collins N, Tian T, O'Malley JT, Emerson RO, Kim JH, Jung Y, Watanabe R, Fuhlbrigge RC, Carbone FR, Gebhardt T, Clark RA, Lin CP, Kupper TS

Staged development of long lived TCRαβ Th17 resident memory T cell population to Candida albicans after skin infection. J Allergy Clin Immunol. 2017;142(2):647-662 - PMID: 29128674 - PMCID: PMC5943196 - DOI: 10.1016/j.jaci.2017.09.042

Sun Z, Kim JH, Kim SH, Kim HR, Zhang K, Pan Y, Ko MK, Kim BM, Chu H, Lee HR, Kim HL, Kim JH, Fu X, Hyun YM, Yun KN, Kim JY, Lee DW, Song SY, Lin CP, Clark RA, Lee KH, Kupper TS, Park CO

Skin-resident natural killer T cells participate in cutaneous allergic inflammation in atopic dermatitis. J Allergy Clin Immunol. 2021;147(5):1764-1777 - PMID: 33516870 - PMCID: PMC9272812 - DOI: 10.1016/j.jaci.2020.11.049

Marshansky V, Futai M

The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function. Curr Opin Cell Biol. 2008;20(4):415-26 - PMID: 18511251 - PMCID: PMC7111286 - DOI: 10.1016/j.ceb.2008.03.015

Naxerova K, Di Stefano B, Makofske JL, Watson EV, de Kort MA, Martin TD, Dezfulian M, Ricken D, Wooten EC, Kuroda MI, Hochedlinger K, Elledge SJ

Integrated loss- and gain-of-function screens define a core network governing human embryonic stem cell behavior. Genes Dev. 2021;35(21-22):1527-1547 - PMID: 34711655 - PMCID: PMC8559676 - DOI: 10.1101/gad.349048.121

Kumar V, Donahue DM, Patel N

An unexpected complication during cardiac catheterization: blood clot cast of the tracheobronchial tree: first case during cardiac catheterization. JACC Cardiovasc Interv. 2013;6(4):e19 - PMID: 23597616 - DOI: 10.1016/j.jcin.2012.11.007

Zeng X, Zou L, Levine RA, Guerrero JL, Handschumacher MD, Sullivan SM, Braithwaite GJ, Stone JR, Solis J, Muratoglu OK, Vlahakes GJ, Hung J

Efficacy of Polymer Injection for Ischemic Mitral Regurgitation: Persistent Reduction of Mitral Regurgitation and Attenuation of Left Ventricular Remodeling. JACC Cardiovasc Interv. 2015;8(2):355-63 - PMID: 25596792 - PMCID: PMC5645299 - DOI: 10.1016/j.jcin.2014.09.016

Shah K, Bureau E, Kim DE, Yang K, Tang Y, Weissleder R, Breakefield XO.

Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression Ann Neurol. 2005;57(1):34-41 - PMID: 15622535 - DOI: 10.1002/ana.20306

Hadjikhani N, Albrecht DS, Mainero C, Ichijo E, Ward N, Granziera C, Zürcher NR, Akeju O, Bonnier G, Price J, Hooker JM, Napadow V, Nahrendorf M, Loggia ML, Moskowitz MA

Extra-axial inflammatory signal in parameninges in migraine with visual aura. Ann Neurol. 2020;87(6):939-949 - PMID: 32239542 - PMCID: PMC7313427 - DOI: 10.1002/ana.25731

Kim J, Jang HJ, Schellingerhout D, Lee SK, Kim H, Kim YD, Lee KY, Choi HY, Cho HJ, Jang SS, Jeon S, Kwon IC, Kim K, Ryu WS, Nahrendorf M, Choi S, Kim DE

Short-Term Cessation of Dabigatran Causes a Paradoxical Prothrombotic State. Ann Neurol. 2020;89(3):444-458 - PMID: 33219556 - DOI: 10.1002/ana.25964

Ryu WS, Schellingerhout D, Hong KS, Jeong SW, Kim BJ, Kim JT, Lee KB, Park TH, Park SS, Park JM, Kang K, Cho YJ, Park HK, Lee BC, Yu KH, Oh MS, Lee SJ, Kim JG, Cha JK, Kim DH, Lee J, Han MK, Park MS, Choi KH, Nahrendorf M, Lee J, Bae HJ, Kim DE

Relation of Pre-stroke Aspirin Use With Cerebral Infarct Volume and Functional Outcomes. Ann Neurol. 2021;90(5):763-776 - PMID: 34536234 - PMCID: PMC9292882 - DOI: 10.1002/ana.26219

Pfirschke C, Zilionis R, Engblom C, Messemaker M, Zou AE, Rickelt S, Gort-Freitas NA, Lin Y, Bill R, Siwicki M, Gungabeesoon J, Sprachman MM, Marquard AN, Rodell CB, Cuccarese MF, Quintana J, Ahmed MS, Kohler RH, Savova V, Weissleder R, Klein AM, Pittet MJ

Macrophage-targeted therapy unlocks antitumoral crosstalk between IFN𝛾-secreting lymphocytes and IL12-producing dendritic cells. Cancer Immunol Res. 2021;10(1):40-55 - PMID: 34795032 - PMCID: PMC10132467 - DOI: 10.1158/2326-6066.CIR-21-0326

Siwicki M, Pittet MJ

Versatile neutrophil functions in cancer. Semin Immunol. 2021;57:101538 - PMID: 34876331 - DOI: 10.1016/j.smim.2021.101538

Snyder PJ, Alber J, Alt C, Bain LJ, Bouma BE, Bouwman FH, DeBuc DC, Campbell MCW, Carrillo MC, Chew EY, Cordeiro MF, Dueñas MR, Fernández BM, Koronyo-Hamaoui M, La Morgia C, Carare RO, Sadda SR, van Wijngaarden P, Snyder HM

Retinal imaging in Alzheimer's and neurodegenerative diseases. Alzheimers Dement. 2020;17(1):103-111 - PMID: 33090722 - PMCID: PMC8062064 - DOI: 10.1002/alz.12179

Leming M, Im H

Differential dementia detection from multimodal brain images in a real-world dataset. Alzheimers Dement. 2025;21:e70362 - PMID: 40596742 - PMCID: PMC12213449 - DOI: 10.1002/alz.70362

Johnson J, Wiley R, Fattouh R, Swirski F, Gajewska B, Coyle A, Gutierrez-Ramos J, Ellis R, Inman M, Jordana M

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am J Resp Crit Care. 2004;169(3):378-85 - PMID: 14597485 - DOI: 10.1164/rccm.200308-1094OC

Ntziachristos V

Fluorescence Molecular Imaging. Annu Rev Biomed Eng. 2006;8:1-33 - PMID: 16834550 - DOI: 10.1146/annurev.bioeng.8.061505.095831

Rohde D, Vandoorne K, Lee IH, Grune J, Zhang S, McAlpine CS, Schloss MJ, Nayar R, Courties G, Frodermann F, Wojtkiewicz G, Honold L, Chen Q, Schmidt S, Iwamoto Y, Sun Y, Cremer S, Hoyer FF, Iborra-Egea O, Muñoz-Guijosa C, Fei Ji F, Zhou B, Adams RH, Wythe JD, Hidalgo J, Watanabe H, Jung Y, van der Laan AM, Piek JJ, Kfoury Y, Désogère PA, Vinegoni C, Dutta P, Sadreyev RI, Caravan P, Bayes-Genis A, Libby P, Scadden DT, Lin CP Naxerova K, Swirski FK, Nahrendorf M

Bone marrow endothelial dysfunction promotes myeloid cell expansion in cardiovascular disease Nat Cardiovasc Res. 2022;1:28–44 - PMID: 35747128 - PMCID: PMC9216333 - DOI: 10.1038/s44161-021-00002-8

Grune J, Lewis AJM, Yamazoe M, Hulsmans M, Rohde D, Xiao L, Zhang S, Ott C, Calcagno DM, Zhou Y, Timm K, Shanmuganathan M, Pulous FE, Schloss MJ, Foy BH, Capen D, Vinegoni C, Wojtkiewicz GR, Iwamoto I, Grune T, Brown D, Higgins J, Ferreira VM, Herring N, Channon KM, Neubauer S, Oxford Acute Myocardial Infarction (OxAMI) Study, Sosnovik DE, Milan DJ, Swirski FK, King KR, Aguirre AD, Ellinor PT, Nahrendorf M

Neutrophils incite and macrophages avert electrical storm after myocardial infarction Nat Cardiovasc Res. 2022;1(7):649-664 - PMID: 36034743 - PMCID: PMC9410341 - DOI: 10.1038/s44161-022-00094-w

Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee IH, Mentkowski K, Grune J, Schloss MJ, Honold L, Iwamoto Y, Zheng Y, Bredella MA, Buckless C, Ghoshhajra B, Thondapu V, van der Laan AM, Piek JJ, Niessen HWM, Pallante F, Carnevale R, Perrotta S, Carnevale D, Iborra-Egea O, Muñoz-Guijosa C, Galvez-Monton C, Bayes-Genis A, Vidoudez C, Trauger SA, Scadden D, Swirski FK, Moskowitz MA, Naxerova K, Nahrendorf M

Bone marrow adipocytes fuel emergency hematopoiesis after myocardial infarction. Nat Cardiovasc Res. 2023;2(12):1277-1290 - PMID: 38344689 - PMCID: PMC10857823 - DOI: 10.1038/s44161-023-00388-7

Pulous FE, Nahrendorf M

Aortic-intima-resident macrophages are guardians of arterial health. Nat Cardiovasc Res. 2022;1(1):4-5 - PMID: 39196109 - DOI: 10.1038/s44161-021-00008-2

Khetarpal SA, Li H, Vitale T, Rhee J, Challa S, Castro C, Pabel S, Sun Y, Liu J, Bogoslavski D, Vargas-Castillo A, Smythers AL, Blackmore KA, Grauvogel L, Mittenbühler MJ, Khandekar MJ, Curtin C, Narvaez-Paliza JM, Wang C, Houstis NE, Sprenger HG, Jurgens SJ, Biddinger KJ, Kuznetsov A, Freeman R, Ellinor PT, Nahrendorf M, Paulo JA, Gygi SP, Dumesic PA, Asnani A, Aragam KG, Puigserver P, Roh JD, Spiegelman BM, Rosenzweig A

Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α. Nat Cardiovasc Res. 2025;4(10):1277-1294 - PMID: 40993371 - DOI: 10.1038/s44161-025-00712-3

Yamazoe M, Ting KKY, Lee IH, Bapat A, Lewis A, Xiao L, Pulous FE, Mentkowski K, Paccalet A, Momin N, Seung H, Dolejsi T, Kumowski N, Schloss MJ, Iwamoto Y, Ramos G, Chan K, Antoniades C, Casadei B, Swirski FK, Ellinor PT, Naxerova K, Pabel S, Hulsmans M, Nahrendorf M

B cells promote atrial fibrillation via autoantibodies. Nat Cardiovasc Res. 2025;4(10):1381-1396 - PMID: 41062615 - PMCID: PMC12520985 - DOI: 10.1038/s44161-025-00724-z

Nahrendorf M, Spindler M, Hu K, Bauer L, Ritter O, Nordbeck P, Quaschning T, Hiller K, Wallis J, Ertl G, Bauer W, Neubauer S

Creatine kinase knockout mice show left ventricular hypertrophy and dilatation, but unaltered remodeling post-myocardial infarction. Cardiovasc Res. 2005;65(2):419-27 - PMID: 15639481 - DOI: 10.1016/j.cardiores.2004.10.006

Nahrendorf M, Frantz S, Hu K, von zur Mahlen C, Tomaszewski M, Scheuermann H, Kaiser R, Jazbutyte V, Beer S, Bauer W, Neubauer S, Ertl G, Allolio B, Callies F

Effect of testosterone on post-myocardial infarction remodeling and function. Cardiovasc Res. 2003;57(2):370-8 - PMID: 12566109 - DOI: 10.1016/s0008-6363(02)00701-0

Pelzer T, Jazbutyte V, Hu K, Segerer S, Nahrendorf M, Nordbeck P, Bonz AW, Muck J, Fritzemeier KH, Hegele-Hartung C, Ertl G, Neyses L

The estrogen receptor-alpha agonist 16alpha-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats. Cardiovasc Res. 2005;67(4):604-12 - PMID: 15950203 - DOI: 10.1016/j.cardiores.2005.04.035

Hu K, Gaudron P, Anders HJ, Weidemann F, Turschner O, Nahrendorf M, Ertl G

Chronic effects of early started angiotensin converting enzyme inhibition and angiotensin AT1-receptor subtype blockade in rats with myocardial infarction: role of bradykinin. Cardiovasc Res. 1998;39(2):401-12 - PMID: 9798525 - DOI: 10.1016/s0008-6363(98)00090-x

Frantz S, Nahrendorf M

Cardiac macrophages and their role in ischemic heart disease. Cardiovasc Res. 2014;102(2):240-8 - PMID: 24501331 - PMCID: PMC3989449 - DOI: 10.1093/cvr/cvu025

Verweij SL, Duivenvoorden R, Stiekema LCA, Nurmohamed NS, van der Valk FM, Versloot M, Verberne HJ, Stroes ESG, Nahrendorf M, Bekkering S, Bernelot Moens SJ

CCR2 expression on circulating monocytes is associated with arterial wall inflammation assessed by 18F-FDG PET/CT in patients at risk for cardiovascular disease. Cardiovasc Res. 2018;114(3):468-475 - PMID: 29186373 - DOI: 10.1093/cvr/cvx224

Hoyer FF, Nahrendorf M

Interferon-ɣ regulates cardiac myeloid cells in myocardial infarction. Cardiovasc Res. 2019;115(13):1815-1816 - PMID: 31161218 - PMCID: PMC6803813 - DOI: 10.1093/cvr/cvz143

Rohde D, Nahrendorf M

Bad company: monocytes in HIV and atherosclerosis. Cardiovasc Res. 2021;117(4):993-994 - PMID: 33693568 - PMCID: PMC7982997 - DOI: 10.1093/cvr/cvab058

Liu T, Meng Z, Liu J, Li J, Zhang Y, Deng Z, Luo S, Wang M, Huang Q, Zhang S, Fendt P, Devouassoux J, Li D, McKenzie ANJ, Nahrendorf M, Libby P, Guo J, Shi GP

Group 2 innate lymphoid cells protect mouse heart from myocardial infarction injury via interleukin 5, eosinophils, and dendritic cells. Cardiovasc Res. 2022;119(4):1046-1061 - PMID: 36063432 - PMCID: PMC10153644 - DOI: 10.1093/cvr/cvac144

Corey KE, Kartoun U, Zheng H, Chung RT, Shaw SY

Using an Electronic Medical Records Database to Identify Non-Traditional Cardiovascular Risk Factors in Nonalcoholic Fatty Liver Disease. Am J Gastroenterol. 2016;111(5):671-6 - PMID: 26925881 - PMCID: PMC4864030 - DOI: 10.1038/ajg.2016.44

Daniel KD, Kim GY, Vassiliou CC, Galindo M, Guimaraes AR, Weissleder R, Charest A, Langer R, Cima MJ

Implantable diagnostic device for cancer monitoring. Biosens Bioelectron. 2009;24(11):3252-7 - PMID: 19442510 - PMCID: PMC2738970 - DOI: 10.1016/j.bios.2009.04.010

Ng EX, Miller MA, Jing T, Chen CH

Single cell multiplexed assay for proteolytic activity using droplet microfluidics. Biosens Bioelectron. 2016;81:408-14 - PMID: 26995287 - DOI: 10.1016/j.bios.2016.03.002

Huber S, Min C, Staat C, Oh J, Castro CM, Haase A, Weissleder R, Gleich B, Lee H

Multichannel digital heteronuclear magnetic resonance biosensor. Biosens Bioelectron. 2018;126:240-248 - PMID: 30445298 - PMCID: PMC6483068 - DOI: 10.1016/j.bios.2018.10.052

Lee CY, Degani I, Cheong J, Lee JH, Choi HJ, Cheon J, Lee H

Fluorescence polarization system for rapid COVID-19 diagnosis Biosens Bioelectron. 2021;178:113049 - PMID: 33540323 - PMCID: PMC7846465 - DOI: 10.1016/j.bios.2021.113049

Oh HK, Kim K, Park J, Im H, Maher S, Kim MG

Plasmon color-preserved gold nanoparticle clusters for high sensitivity detection of SARS-CoV-2 based on lateral flow immunoassay. Biosens Bioelectron. 2022;205:114094 - PMID: 35202985 - PMCID: PMC8851749 - DOI: 10.1016/j.bios.2022.114094

Ansah IB, Leming M, Lee SH, Yang JY, Mun C, Noh K, An T, Lee S, Kim DH, Kim M, Im H, Park SG

Label-free detection and discrimination of respiratory pathogens based on electrochemical synthesis of biomaterials-mediated plasmonic composites and machine learning analysis. Biosens Bioelectron. 2023;227:115178 - PMID: 36867960 - PMCID: PMC10165532 - DOI: 10.1016/j.bios.2023.115178

Kwak TJ, Son T, Hong JS, Winter UA, Jeong MH, McLean C, Weissleder R, Lee H, Castro CM, Im H

Electrokinetically enhanced label-free plasmonic sensing for rapid detection of tumor-derived extracellular vesicles. Biosens Bioelectron. 2023;237:115422 - PMID: 37301179 - PMCID: PMC10527155 - DOI: 10.1016/j.bios.2023.115422

Lee S, Lee J, Kim H, Lee H, Park HG

Novel lateral flow assay to detect H2O2 by utilizing self-biotinylation of G-quadruplex. Biosens Bioelectron. 2024;267:116811 - PMID: 39378787 - DOI: 10.1016/j.bios.2024.116811

Cho YK, Choi Y, Kim S, Kim H, Chow KF, Shin IS, Park JH, Lee H

Scalable electrochemical system for rapid on-site detection of food allergens. Biosens Bioelectron. 2025;273:117142 - PMID: 39832405 - PMCID: PMC11788024 - DOI: 10.1016/j.bios.2025.117142

Woo HK, Nam Y, Park HG, Lee H

Bridging laboratory innovation to translational research and commercialization of extracellular vesicle isolation and detection. Biosens Bioelectron. 2025;282:117475 - PMID: 40300344 - PMCID: PMC12076185 - DOI: 10.1016/j.bios.2025.117475

Rashidian M, Keliher E, Dougan M, Juras PK, Cavallari M, Wojtkiewicz GR, Jacobsen J, Edens JG, Tas JM, Victora G, Weissleder R, Ploegh H

The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer. ACS Cent Sci. 2015;1(3):142-147 - PMID: 26955657 - PMCID: PMC4778250 - DOI: 10.1021/acscentsci.5b00121

Kilic T, Cho YK, Jeong N, Shin IS, Carter BS, Balaj L, Weissleder R, Lee H

Multielectrode Spectroscopy Enables Rapid and Sensitive Molecular Profiling of Extracellular Vesicles. ACS Cent Sci. 2022;8(1):110-117 - PMID: 35111901 - PMCID: PMC8802188 - DOI: 10.1021/acscentsci.1c01193

Quintana JM, Kang M, Hu H, Ng TSC, Wojtkiewicz GR, Scott E, Parangi S, Schuemann J, Weissleder R, Miller MA

Extended Pharmacokinetics Improve Site-Specific Prodrug Activation Using Radiation. ACS Cent Sci. 2024;10(7):1371-1382 - PMID: 39071065 - PMCID: PMC11273447 - DOI: 10.1021/acscentsci.4c00354

Staudt M, Carlson JCT

Building a Medicinal Chemistry Framework for Bioorthogonal Probes. ACS Cent Sci. 2025;11(6):823-825 - PMID: 40606006 - PMCID: PMC12220826 - DOI: 10.1021/acscentsci.5c00917

Zaharchuk G, Mandeville JB, Bogdanov AA Jr, Weissleder R, Rosen BR, Marota JJ

Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension Stroke. 1999;30:2197-204; discussion 2204-5 - PMID: 10512929 - DOI: 10.1161/01.str.30.10.2197

Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R

Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine Model Stroke. 2004;35:952-7 - PMID: 14988578 - DOI: 10.1161/01.STR.0000120308.21946.5D

Kim DE, Kim JY, Nahrendorf M, Lee SK, Ryu JH, Kim K, Kwon IC, Schellingerhout D

Direct Thrombus Imaging as a Means to Control the Variability of Mouse Embolic Infarct Models: The Role of Optical Molecular Imaging. Stroke. 2011;42(12):3566-73 - PMID: 22020025 - DOI: 10.1161/STROKEAHA.111.629428

Kim DE, Kim JY, Schellingerhout D, Ryu JH, Lee SK, Jeon S, Lee JS, Kim J, Jang HJ, Park JE, Kim EJ, Kwon IC, Ahn CH, Nahrendorf M, Kim K

Quantitative Imaging of Cerebral Thromboemboli In Vivo: The Effects of Tissue-Type Plasminogen Activator. Stroke. 2017;48(5):1376-1385 - PMID: 28432262 - DOI: 10.1161/STROKEAHA.117.016511

Jang HJ, Kim J, Kim H, Kim T, Chung J, Cremer S, Krohn-Grimberghe M, Kim EJ, Schellingerhout D, Nahrendorf M, Kim DE

Inhibiting Monocyte Migration Reduces Arterial Thrombosis and Facilitates Thrombolysis. Stroke. 2025;56(12):3438-3453 - PMID: 41070446 - PMCID: PMC12636086 - DOI: 10.1161/STROKEAHA.125.052352

Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura N, Ohguchi H, Cottini F, Jakubikova J, Munshi NC, Haggarty SJ, Richardson PG, Hideshima T, Anderson KC

Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myeloma. Leukemia. 2013;28(3):680-9 - PMID: 23913134 - PMCID: PMC4165599 - DOI: 10.1038/leu.2013.231

Hideshima T, Mazitschek R, Santo L, Mimura N, Gorgun G, Richardson PG, Raje N, Anderson KC

Induction of differential apoptotic pathways in multiple myeloma cells by class selective histone deacetylase inhibitors. Leukemia. 2013;28(2):457-60 - PMID: 24150220 - PMCID: PMC4405100 - DOI: 10.1038/leu.2013.301

Eda H, Santo L, Cirstea DD, Yee AJ, Scullen TA, Nemani N, Mishima Y, Waterman PR, Arastu-Kapur S, Evans E, Singh J, Kirk CJ, Westlin WF, Raje NS

A novel Bruton's tyrosine kinase inhibitor CC-292 in combination with the proteasome inhibitor carfilzomib impacts the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity. Leukemia. 2014;28(9):1892-901 - PMID: 24518207 - DOI: 10.1038/leu.2014.69

Touhami M, Fauvel-Lafève F, Da Silva N, Chomienne C, Legrand C

Induction of thrombospondin-1 by all-trans retinoic acid modulates growth and differentiation of HL-60 myeloid leukemia cells. Leukemia. 1997;11(12):2137-42 - PMID: 9447832 - DOI: 10.1038/sj.leu.2400866

Gruss HJ, DaSilva N, Hu ZB, Uphoff CC, Goodwin RG, Drexler HG

Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines. Leukemia. 1994;8(12):2083-94 - PMID: 7528856

DaSilva N, Hu ZB, Ma W, Rosnet O, Birnbaum D, Drexler HG

Expression of the FLT3 gene in human leukemia-lymphoma cell lines. Leukemia. 1994;8(5):885-8 - PMID: 8182945

Harada T, Ohguchi H, Grondin Y, Kikuchi S, Sagawa M, Tai YT, Mazitschek R, Hideshima T, Anderson KC

HDAC3 regulates DNMT1 expression in multiple myeloma: Therapeutic implications. Leukemia. 2017;31(12):2670-2677 - PMID: 28490812 - PMCID: PMC5681897 - DOI: 10.1038/leu.2017.144

Yassin M, Aqaqe N, Yassin AA, van Galen P, Kugler E, Bernstein BE, Koren-Michowitz M, Canaani J, Nagler A, Lechman ER, Dick JE, Wienholds E, Izraeli S, Milyavsky M

A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity. Leukemia. 2019;33(8):2061-2077 - PMID: 30705411 - DOI: 10.1038/s41375-019-0386-z

Ho M, Chen T, Liu J, Dowling P, Hideshima T, Zhang L, Morelli E, Camci-Unal G, Wu X, Tai YT, Wen K, Samur M, Schlossman RL, Mazitschek R, Kavanagh EL, Lindsay S, Harada T, McCann A, Anderson KC, O'Gorman P, Bianchi G

Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling. Leukemia. 2019;34(1):196-209 - PMID: 31142847 - PMCID: PMC6883144 - DOI: 10.1038/s41375-019-0493-x

Mendenhall EM, Bernstein BE

DNA-protein interactions in high definition. Genome Biol. 2012;13(1):139 - PMID: 22283870 - PMCID: PMC3334573 - DOI: 10.1186/gb-2012-13-1-139

Ku M, Jaffe JD, Koche RP, Rheinbay E, Endoh M, Koseki H, Carr SA, Bernstein BE

H2A.Z landscapes and dual modifications in pluripotent and multipotent stem cells underlie complex genome regulatory functions. Genome Biol. 2012;13(10):R85 - PMID: 23034477 - PMCID: PMC3491413 - DOI: 10.1186/gb-2012-13-10-r85

Herman JD, Rice DP, Ribacke U, Silterra J, Deik AA, Moss EL, Broadbent KM, Neafsey DE, Desai MM, Clish CB, Mazitschek R, Wirth DF

A genomic and evolutionary approach reveals non-genetic drug resistance in malaria. Genome Biol. 2014;15(11):511 - PMID: 25395010 - PMCID: PMC4272547 - DOI: 10.1186/PREACCEPT-1067113631444973

Naxerova K, Bult CJ, Peaston A, Fancher K, Knowles BB, Kasif S, Kohane IS

Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers. Genome Biol. 2008;9(7):R108 - PMID: 18611264 - PMCID: PMC2530866 - DOI: 10.1186/gb-2008-9-7-r108

Eyler CE, Matsunaga H, Hovestadt V, Vantine SJ, van Galen P, Bernstein BE

Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance. Genome Biol. 2020;21(1):174 - PMID: 32669109 - PMCID: PMC7364565 - DOI: 10.1186/s13059-020-02085-1

Danaher P, McGuire D, Wu L, Patrick M, Kroeppler D, Zhai H, Olgun DG, Gong D, Cao J, Hwang WL, Schmid J, Beechem JM

InSituCor: exploring spatially correlated genes conditional on the cell type landscape. Genome Biol. 2025;26(1):105 - PMID: 40275395 - PMCID: PMC12020328 - DOI: 10.1186/s13059-025-03554-1

Chen W, Sun CC, Chen S, Meynard D, Babitt JL, Lin HY

A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum. Haematologica. 2012;98(2):296-304 - PMID: 22875629 - PMCID: PMC3561439 - DOI: 10.3324/haematol.2012.070136

Ramsey H, Zhang Q, Brown DE, Steensma DP, Lin CP, Wu MX

Stress-induced hematopoietic failure in the absence of immediate early response gene X-1. Haematologica. 2013;99(2):282-91 - PMID: 24056813 - PMCID: PMC3912958 - DOI: 10.3324/haematol.2013.092452

Geisness AC, Azul M, Williams D, Szafraniec H, De Souza DC, Higgins JM, Wood DK

Ionophore-mediated swelling of erythrocytes as a therapeutic mechanism in sickle cell disease. Haematologica. 2021;107(6):1438-1447 - PMID: 34706495 - PMCID: PMC9152977 - DOI: 10.3324/haematol.2021.278666

Chung J*, Shao H*, Reiner T, Issadore D, Weissleder R, Lee H

Cell Sorting: Microfluidic Cell Sorter (μFCS) for On-chip Capture and Analysis of Single Cells Adv Healthc Mater. 2012;1(4):432-6 - PMID: 23184773 - PMCID: PMC3508764 - DOI: 10.1002/adhm.201200046

Issadore D*, Chung HJ*, Chung J, Budin G, Weissleder R*, Lee H*

μHall Chip for Sensitive Detection of Bacteria Adv Healthc Mater. 2013;2(9):1224-8 - PMID: 23495188 - PMCID: PMC4340655 - DOI: 10.1002/adhm.201200380

Liong M, Im H, Majmudar MD, Aguirre AD, Sebas M, Lee H*, Weissleder R*

Magnetic Ligation Method for Quantitative Detection of MicroRNAs. Adv Healthc Mater. 2014;3(7):1015-9 - PMID: 24532323 - PMCID: PMC4107040 - DOI: 10.1002/adhm.201300672

Hong S, Carlson J, Lee H, Weissleder R

Bioorthogonal Radiopaque Hydrogel for Endoscopic Delivery and Universal Tissue Marking. Adv Healthc Mater. 2015;5(4):421-426 - PMID: 26688173 - PMCID: PMC4811597 - DOI: 10.1002/adhm.201500780

Gessner I, Park JH, Lin HY, Lee H, Weissleder R

Magnetic Gold Nanoparticles with Idealized Coating for Enhanced Point-Of-Care Sensing. Adv Healthc Mater. 2021;11(2):e2102035 - PMID: 34747576 - PMCID: PMC8770610 - DOI: 10.1002/adhm.202102035

Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R

Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis. Brain. 2008;131(Pt 4):1123-33 - PMID: 18234693 - PMCID: PMC4044727 - DOI: 10.1093/brain/awn004

Polasek M, Fuchs BC, Uppal R, Schühle DT, Alford JK, Loving GS, Yamada S, Wei L, Lauwers GY, Guimaraes AR, Tanabe KK, Caravan P

Molecular MR Imaging of Liver Fibrosis: A Feasibility Study using Rat and Mouse Models. J Hepatol. 2012;57(3):549-55 - PMID: 22634342 - PMCID: PMC3423553 - DOI: 10.1016/j.jhep.2012.04.035

Ladapo JA, Jaffer FA, Weinstein MC, Froelicher ES

Projected Cost-effectiveness of Smoking Cessation Interventions in Patients Hospitalized With Myocardial Infarction. Arch Intern Med. 2011;171(1):39-45 - PMID: 21220659 - DOI: 10.1001/archinternmed.2010.479

Conedera FM, Runnels JM, Stein JV, Alt C*, Enzmann V*, Lin CP*

Assessing the role of T cells in response to retinal injury to uncover new therapeutic targets for the treatment of retinal degeneration. J Neuroinflammation. 2023;20(1):206 - PMID: 37689689 - PMCID: PMC10492418 - DOI: 10.1186/s12974-023-02867-x

Conedera FM, Kokona D, Zinkernagel MS, Stein JV, Lin CP, Alt C, Enzmann V

Macrophages coordinate immune response to laser-induced injury via extracellular traps. J Neuroinflammation. 2024;21(1):68 - PMID: 38500151 - PMCID: PMC10949579 - DOI: 10.1186/s12974-024-03064-0

Bogdanov A, Weissleder R

The development of in vivo imaging systems to study gene expression. Trends Biotechnol. 1998;16(1):5-10 - PMID: 9470227 - DOI: 10.1016/S0167-7799(97)01150-5

Zhao M, Weissleder R

Intracellular cargo delivery using tat peptide and derivatives Med Res Rev. 2004;24:1-12 - PMID: 14595670 - DOI: 10.1002/med.10056

Pittet M, Zippelius A, Valmori D, Speiser D, Cerottini J, Romero P

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor. Trends Immunol. 2002;23:325-8 - PMID: 12103339 - DOI: 10.1016/s1471-4906(02)02244-5

Squadrito ML, Etzrodt M, De Palma M, Pittet MJ

MicroRNA-mediated control of macrophages and its implications for cancer. Trends Immunol. 2013;34(7):350-9 - PMID: 23498847 - PMCID: PMC3700601 - DOI: 10.1016/j.it.2013.02.003

Swirski FK, Robbins CS, Nahrendorf M

Development and Function of Arterial and Cardiac Macrophages. Trends Immunol. 2016;37(1):32-40 - PMID: 26748179 - PMCID: PMC4706986 - DOI: 10.1016/j.it.2015.11.004

Armstrong JF, Campo B, Alexander SPH, Arendse LB, Cheng X, Davenport AP, Faccenda E, Fidock DA, Godinez-Macias KP, Harding SD, Kato N, Lee MCS, Luth MR, Mazitschek R, Mittal N, Niles JC, Okombo J, Ottilie S, Pasaje CFA, Probst AS, Rawat M, Rocamora F, Sakata-Kato T, Southan C, Spedding M, Tye MA, Yang T, Zhao N, Davies JA

Advances in Malaria Pharmacology and the online Guide to MALARIA PHARMACOLOGY: IUPHAR Review X. Br J Pharmacol. 2023;180(15):1899-1929 - PMID: 37197802 - DOI: 10.1111/bph.16144

Taghdiri N, Calcagno DM, Fu Z, Huang K, Kohler RH, Weissleder R, Coleman TP, King KR

Macrophage calcium reporter mice reveal immune cell communication in vitro and in vivo. Cell Rep Methods. 2021;1(8):ePub - PMID: 35079727 - PMCID: PMC8786215 - DOI: 10.1016/j.crmeth.2021.100132

Yue H, Nowak RP, Overwijn D, Payne NC, Fischinger S, Atyeo C, Lam EC, St Denis K, Brais LK, Konishi Y, Sklavenitis-Pistofidis R, Baden LR, Nilles EJ, Karlson EW, Yu XG, Li JZ, Woolley AE, Ghobrial IM, Meyerhardt JA, Balazs AB, Alter G, Mazitschek R, Fischer ES

Diagnostic TR-FRET assays for detection of antibodies in patient samples. Cell Rep Methods. 2023;3(3):100421 - PMID: 37056371 - PMCID: PMC10088089 - DOI: 10.1016/j.crmeth.2023.100421

Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen P, Chiocca EA, Lawler SE

Preclinical investigation of gene-mediated cytotoxic immunotherapy and checkpoint blockade in glioblastoma. Neuro Oncol. 2018;20(2):225-235 - PMID: 29016938 - PMCID: PMC5777502 - DOI: 10.1093/neuonc/nox139

Fraser K, Jo A, Giedt J, Vinegoni C, Yang KS, Peruzzi P, Chiocca EA, Breakefield XO, Lee H, Weissleder R

Characterization of single microvesicles in plasma from glioblastoma patients. Neuro Oncol. 2019;21(5):606-615 - PMID: 30561734 - PMCID: PMC6502493 - DOI: 10.1093/neuonc/noy187

Hwang WL, Marciscano AE, Niemierko A, Kim DW, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Loeffler JS, Oh KS, Shih HA, Larvie M

Imaging and extent of surgical resection predict risk of meningioma recurrence better than WHO histopathological grade. Neuro Oncol. 2015;18(6):863-72 - PMID: 26597949 - PMCID: PMC4864259 - DOI: 10.1093/neuonc/nov285

Chen E, Ling AL, Reardon DA, Chiocca EA

Lessons learned from phase 3 trials of immunotherapy for glioblastoma: Time for longitudinal sampling? Neuro Oncol. 2024;26(2):211-225 - PMID: 37995317 - PMCID: PMC10836778 - DOI: 10.1093/neuonc/noad211

Ling AL, Chiocca EA

Oncolytic immunoactivation associates with survival in a glioblastoma clinical trial. Neuro Oncol. 2024;26(2):209-210 - PMID: 37941468 - PMCID: PMC10836764 - DOI: 10.1093/neuonc/noad216

Chand S, Jo A, Vellichirammal NN, Gowen A, Guda C, Schaal V, Odegaard K, Lee H, Pendyala G, Yelamanchili AV

Comprehensive Characterization of Nanosized Extracellular Vesicles from Central and Peripheral Organs: Implications for Preclinical and Clinical Applications ACS Appl Mater Interfaces. 2020;9:8906–8919 - DOI: 10.1021/acsanm.0c01654

Choi JH, Chin LK, Woo BM, Song Y, Seol MJ, Hong Y, Liu AQ, Jang S, Ploegh H, Im H, Lee D

Hydrogel-Based Stamping Technology for Solution-Free Blood Cell Staining. ACS Appl Mater Interfaces. 2021;13(19):22124-22130 - PMID: 33870697 - DOI: 10.1021/acsami.0c22521

Kim K, Son T, Hong JS, Kwak TJ, Jeong MH, Weissleder R, Im H

Physisorption of Affinity Ligands Facilitates Extracellular Vesicle Detection with Low Non-Specific Binding to Plasmonic Gold Substrates. ACS Appl Mater Interfaces. 2022;14(23):26548-26556 - PMID: 35653580 - PMCID: PMC9715849 - DOI: 10.1021/acsami.2c07317

Chin LK, Li H, Choi JH, Iwamoto Y, Oh J, Min J, Beak SK, Yoo D, Castro CM, Lee D, Im H

Hydrogel Stamping for Rapid, Multiplexed, Point-of-Care Immunostaining of Cells and Tissues. ACS Appl Mater Interfaces. 2022;14(24):27613-27622 - PMID: 35671240 - DOI: 10.1021/acsami.2c05071

Arai MS, Kim H, Pascavis M, Cha B, Brambilla G, Cho YK, Park J, Vilela RRC, de Camargo ASS, Castro CM, Lee H

Upconverting Nanoparticle-based Enhanced Luminescence Lateral-Flow Assay for Urinary Biomarker Monitoring. ACS Appl Mater Interfaces. 2024;16(29):38243-38251 - PMID: 38980927 - DOI: 10.1021/acsami.4c06117

You DG, Jung JM, Kim CH, An JY, Bui VD, Lee J, Um W, Jo DG, Cho YW, Lee DS, Balaj L, Lee H, Park JH

Stem Cell-Derived Extracellular Vesicle-Bearing Injectable Hydrogel for Collagen Generation in Dermis. ACS Appl Mater Interfaces. 2024;16(29):37698-37706 - PMID: 38980897 - DOI: 10.1021/acsami.4c07434

Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bunemann M

Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends Pharmacol Sci. 2008;29(3):159-65 - PMID: 18262662 - DOI: 10.1016/j.tips.2007.12.002

Liao KP, Diogo D, Cui J, Cai T, Okada Y, Gainer VS, Murphy SN, Gupta N, Mirel D, Ananthakrishnan AN, Szolovits P, Shaw SY, Raychaudhuri S, Churchill S, Kohane I, Karlson EW, Plenge RM

Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls. Ann Rheum Dis. 2013;73(6):1170-1175 - PMID: 23716066 - PMCID: PMC3815491 - DOI: 10.1136/annrheumdis-2012-203202

Libby P, DiCarli M, Weissleder R

The Vascular Biology of Atherosclerosis and Imaging Targets. J Nucl Med. 2010;51 Suppl 1:33S-37S - PMID: 20395349 - DOI: 10.2967/jnumed.109.069633

Kramer CM, Sinusas AJ, Sosnovik DE, French BA, Bengel FM

Multimodality Imaging of Myocardial Injury and Remodeling. J Nucl Med. 2010;51 Suppl 1:107S-121S - PMID: 20395347 - PMCID: PMC3078824 - DOI: 10.2967/jnumed.109.068221

Bogdanov AA, Callahan RJ, Wilkinson RA, Martin C, Cameron JA, Fischman AJ, Brady TJ, Weissleder R

Synthetic copolymer kit for radionuclide blood-pool imaging. J Nucl Med. 1994;35(11):1880-6 - PMID: 7965173

Majmudar MD, Nahrendorf M

Cardiovascular Molecular Imaging: The Road Ahead. J Nucl Med. 2012;53(5):673-676 - PMID: 22492729 - PMCID: PMC3744821 - DOI: 10.2967/jnumed.111.099838

Zeglis BM, Sevak KK, Reiner T, Mohindra P, Carlin SD, Zanzonico P, Weissleder R, Lewis JS

A Pretargeted PET Imaging Strategy Based on Bioorthogonal Diels-Alder Click Chemistry. J Nucl Med. 2013;54(8):1389-96 - PMID: 23708196 - PMCID: PMC4151562 - DOI: 10.2967/jnumed.112.115840

Kilcoyne A, Harisinghani MG, Mahmood U

Prostate Cancer Imaging and Therapy: Potential Role of Nanoparticles. J Nucl Med. 2016;57(Suppl 3):105S-110S - PMID: 27694162 - DOI: 10.2967/jnumed.115.170738

Quintana JM*, Jiang F*, Kang M, Valladolid Onecha V, Könik A, Qin L, Rodriguez VE, Hu H, Borges N, Khurana I, Banla LI, Le Fur M, Caravan P, Schuemann J, Bertolet A, Weissleder R, Miller MA, Ng TSC

Localized In Vivo Prodrug Activation Using Radionuclides. J Nucl Med. 2025;66(1):91-97 - PMID: 39753366 - PMCID: PMC11705795 - DOI: 10.2967/jnumed.124.268559

Morini E, Gao D, Montgomery CM, Salani M, Mazzasette C, Krussig TA, Swain B, Dietrich P, Narasimhan J, Gabbeta V, Dakka A, Hedrick J, Zhao X, Weetall M, Naryshkin NA, Wojtkiewicz GG, Ko CP, Talkowski ME, Dragatsis I, Slaugenhaupt SA

ELP1 Splicing Correction Reverses Proprioceptive Sensory Loss in Familial Dysautonomia. Am J Hum Genet. 2019;104(4):638-650 - PMID: 30905397 - PMCID: PMC6451698 - DOI: 10.1016/j.ajhg.2019.02.009

Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D

Impaired Tubular Uptake Explains Albuminuria in Early Diabetic Nephropathy. J Am Soc Nephrol. 2008;20(3):489-94 - PMID: 19118149 - PMCID: PMC2653682 - DOI: 10.1681/ASN.2008050503

Izawa A*, Ueno T*, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R

Importance of donor- and recipient-derived selectins in cardiac allograft rejection. J Am Soc Nephrol. 2007;18(11):2929-36 - PMID: 17928506 - DOI: 10.1681/ASN.2006111261

Ueno T, Tanaka K, Jurewicz M, Murayama T, Guleria I, Fiorina P, Paez JC, Augello A, Vergani A, Wong M, Smith RN, Abdi R

Divergent role of donor dendritic cells in rejection versus tolerance of allografts. J Am Soc Nephrol. 2009;20(3):535-44 - PMID: 19129312 - PMCID: PMC2653678 - DOI: 10.1681/ASN.2008040377

Xia Y, Babitt JL, Bouley R, Zhang Y, Silva ND, Chen S, Zhuang Z, Samad TA, Brenner GJ, Anderson JL, Hong CC, Schneyer AL, Brown D, Lin HY

Dragon Enhances BMP Signaling and Increases Transepithelial Resistance in Kidney Epithelial Cells. J Am Soc Nephrol. 2010;21(4):666-77 - PMID: 20167703 - PMCID: PMC2844302 - DOI: 10.1681/ASN.2009050511

Bouley R, Lu HA, Nunes P, Da Silva N, McLaughlin M, Chen Y, Brown D

Calcitonin Has a Vasopressin-like Effect on Aquaporin-2 Trafficking and Urinary Concentration. J Am Soc Nephrol. 2010;22(1):59-72 - PMID: 21071524 - PMCID: PMC3014035 - DOI: 10.1681/ASN.2009121267

Breton S, Marsolais M, Lapointe JY, Laprade R

Cell volume increases of physiologic amplitude activate basolateral K and CI conductances in the rabbit proximal convoluted tubule. J Am Soc Nephrol. 1996;7(10):2072-87 - PMID: 8915967 - DOI: 10.1681/ASN.V7102072

Breton S, Brown D

Cold-induced microtubule disruption and relocalization of membrane proteins in kidney epithelial cells. J Am Soc Nephrol. 1998;9(2):155-66 - PMID: 9527391 - DOI: 10.1681/ASN.V92155

Sabolić I, Herak-Kramberger CM, Breton S, Brown D

Na/K-ATPase in intercalated cells along the rat nephron revealed by antigen retrieval. J Am Soc Nephrol. 1999;10(5):913-22 - PMID: 10232676 - DOI: 10.1681/ASN.V105913

Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Desch

Pendrin regulation in mouse kidney primarily is chloride-dependent. J Am Soc Nephrol. 2006;17(8):2153-63 - PMID: 16825334 - DOI: 10.1681/ASN.2005101054

Brown D, Wagner CA

Molecular Mechanisms of Acid-Base Sensing by the Kidney. J Am Soc Nephrol. 2012;23(5):774-80 - PMID: 22362904 - PMCID: PMC3338302 - DOI: 10.1681/ASN.2012010029

Chen Y, Rice W, Gu Z, Li J, Huang J, Brenner MB, Van Hoek A, Xiong J, Gundersen GG, Norman JC, Hsu VW, Fenton RA, Brown D, Lu HA

Aquaporin 2 Promotes Cell Migration and Epithelial Morphogenesis. J Am Soc Nephrol. 2012;23(9):1506-17 - PMID: 22859853 - PMCID: PMC3431417 - DOI: 10.1681/ASN.2012010079

Babitt JL, Lin HY

Mechanisms of Anemia in CKD. J Am Soc Nephrol. 2012;23(10):1631-4 - PMID: 22935483 - PMCID: PMC3458456 - DOI: 10.1681/ASN.2011111078

Brown D, Jenny Lu HA

Aquaporin-2 Inhibitors: Fishing in the Chemical Pool. J Am Soc Nephrol. 2013;24(5):685-6 - PMID: 23599384 - DOI: 10.1681/ASN.2013030243

Cheung PW, Nomura N, Nair AV, Pathomthongtaweechai N, Ueberdiek L, Jenny Lu HA, Brown D, Bouley R

EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption. J Am Soc Nephrol. 2016;:ePub - PMID: 26961350 - DOI: 10.1681/ASN.2015080903

Trepiccione F, Gerber SD, Grahammer F, López-Cayuqueo KI, Baudrie V, Păunescu TG, Capen DE, Picard N, Alexander RT, Huber TB, Chambrey R, Brown D, Houillier P, Eladari D, Simons M

Renal Atp6ap2/(Pro)renin Receptor Is Required for Normal Vacuolar H+-ATPase Function but Not for the Renin-Angiotensin System. J Am Soc Nephrol. 2016;27(11):3320-3330 - PMID: 27044666 - PMCID: PMC5084887 - DOI: 10.1681/ASN.2015080915

Cheung PW, Nomura N, Nair AV, Pathomthongtaweechai N, Ueberdiek L, Lu HA, Brown D, Bouley R

EGF Receptor Inhibition by Erlotinib Increases Aquaporin 2-Mediated Renal Water Reabsorption. J Am Soc Nephrol. 2016;27(10):3105-3116 - PMID: 27694161 - PMCID: PMC5042667 - DOI: 10.1681/ASN.2015080903

Mumtaz R, Trepiccione F, Hennings JC, Huebner AK, Serbin B, Picard N, Ullah AK, Păunescu TG, Capen DE, Lashhab RM, Mouro-Chanteloup I, Alper SL, Wagner CA, Cordat E, Brown D, Eladari D, Hübner CA

Intercalated Cell Depletion and Vacuolar H+-ATPase Mistargeting in an AE1 R607H Knockin Model. J Am Soc Nephrol. 2016;28(5):1507-1520 - PMID: 27932475 - PMCID: PMC5407715 - DOI: 10.1681/ASN.2016020169

Nigwekar SU, Weiser JM, Kalim S, Xu D, Wibecan JL, Dougherty SM, Mercier-Lafond L, Corapi KM, Eneanya ND, Holbrook EH, Brown D, Thadhani RI, Păunescu TG

Characterization and Correction of Olfactory Deficits in Kidney Disease. J Am Soc Nephrol. 2017;28(11):3395-3403 - PMID: 28775001 - PMCID: PMC5661283 - DOI: 10.1681/ASN.2016121308

Battistone MA, Nair AV, Barton CR, Liberman RN, Peralta MA, Capen DE, Brown D, Breton S

Extracellular Adenosine Stimulates Vacuolar ATPase-Dependent Proton Secretion in Medullary Intercalated Cells. J Am Soc Nephrol. 2017;29(2):545-556 - PMID: 29222395 - PMCID: PMC5791049 - DOI: 10.1681/ASN.2017060643

Leaf DE, Rajapurkar M, Lele SS, Mukhopadhyay B, Boerger EAS, Mc Causland FR, Eisenga MF, Singh K, Babitt JL, Kellum JA, Palevsky PM, Christov M, Waikar SS

Iron, Hepcidin, and Death in Human AKI. J Am Soc Nephrol. 2019;30(3):493-504 - PMID: 30737269 - PMCID: PMC6405140 - DOI: 10.1681/ASN.2018100979

Little MH, Brown D, Humphreys BD, McMahon AP, Miner JH, Sands JM, Weisz OA, Mullins C, Hoshizaki D,

Defining Kidney Biology to Understand Renal Disease. Clin J Am Soc Nephrol. 2013;9(4):809-11 - PMID: 24370769 - PMCID: PMC3974369 - DOI: 10.2215/CJN.10851013

Soehnlein O, Swirski FK

Hypercholesterolemia links hematopoiesis with atherosclerosis. Trends Endocrin Met. 2012;24(3):129-136 - PMID: 23228326 - PMCID: PMC4302393 - DOI: 10.1016/j.tem.2012.10.008

Jeong MH, Im H*, Dahl JB*

Non-contact microfluidic analysis of the stiffness of single large extracellular vesicles from IDH1-mutated glioblastoma cells. Adv Mater Technol. 2023;8(7):ePub - PMID: 37649709 - PMCID: PMC10465107 - DOI: 10.1002/admt.202201412

Corradini E, Babitt JL, Lin HY

The RGM/DRAGON family of BMP co-receptors. Cytokine Growth Factor Rev. 2009;20(5-6):389-98 - PMID: 19897400 - PMCID: PMC3715994 - DOI: 10.1016/j.cytogfr.2009.10.008

Hilderbrand SA, Weissleder R

Near-infrared fluorescence: application to in vivo molecular imaging. Curr Opin Chem Biol. 2009;14:1-9 - PMID: 19879798 - DOI: 10.1016/j.cbpa.2009.09.029

Ng TSC, Allen HH, Rashidian M, Miller MA

Probing immune infiltration dynamics in cancer by in-vivo imaging. Curr Opin Chem Biol. 2022;67:102117 - PMID: 35219177 - PMCID: PMC9118268 - DOI: 10.1016/j.cbpa.2022.102117

Fu W, Farache J, Clardy SM, Hattori K, Mander P, Lee K, Rioja I, Weissleder R, Prinjha RK, Benoist C, Mathis D

Epigenetic modulation of type-1 diabetes via a dual effect on pancreatic macrophages and β cells. eLife. 2014;3:e04631 - PMID: 25407682 - PMCID: PMC4270084 - DOI: 10.7554/eLife.04631

Khor B, Gagnon JD, Goel G, Roche MI, Conway KL, Tran K, Aldrich LN, Sundberg TB, Paterson AM, Mordecai S, Dombkowski D, Schirmer M, Tan PH, Bhan AK, Roychoudhuri R, Restifo NP, O'Shea JJ, Medoff BD, Shamji AF, Schreiber SL, Sharpe AH, Shaw SY, Xavier RJ

The kinase DYRK1A reciprocally regulates the differentiation of Th17 and regulatory T cells. eLife. 2015;4:ePub - PMID: 25998054 - PMCID: PMC4441007 - DOI: 10.7554/eLife.05920

Shah N, Wang P, Wongvipat J, Karthaus WR, Abida W, Armenia J, Rockowitz S, Drier Y, Bernstein BE, Long HW, Freedman ML, Arora VK, Zheng D, Sawyers CL

Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancer. eLife. 2017;6:ePub - PMID: 28891793 - PMCID: PMC5593504 - DOI: 10.7554/eLife.27861

Naxerova K, Elledge SJ

Taking the brakes off telomerase. eLife. 2015;4:ePub - PMID: 26194808 - PMCID: PMC4507575 - DOI: 10.7554/eLife.09519

Chaudhury A, Miller GD, Eichner D, Higgins JM

Single-cell modeling of routine clinical blood tests reveals transient dynamics of human response to blood loss. eLife. 2019;8:ePub - PMID: 31845889 - PMCID: PMC6917488 - DOI: 10.7554/eLife.48590

Harada BT, Hwang WL, Deindl S, Chatterjee N, Bartholomew B, Zhuang X

Stepwise nucleosome translocation by RSC remodeling complexes. eLife. 2016;5:ePub - PMID: 26895087 - PMCID: PMC4769157 - DOI: 10.7554/eLife.10051

Shah VS, Hou J, Vinarsky V, Xu J, Surve M, Lin CP, Rajagopal J

Autofluorescence imaging permits label free cell type assignment in unmodified airway and reveals the dynamic formation of airway secretory cell associated antigen passages (SAPs). eLife. 2023;12:ePub - PMID: 36994985 - PMCID: PMC10154029 - DOI: 10.7554/eLife.84375

Mandt REK, Luth MR, Tye MA, Mazitschek R, Ottilie S, Winzeler EA, Lafuente-Monasterio MJ, Gamo FJ, Wirth DF, Lukens AK

Diverse evolutionary pathways challenge the use of collateral sensitivity as a strategy to suppress resistance. eLife. 2023;12:ePub - PMID: 37737220 - PMCID: PMC10695565 - DOI: 10.7554/eLife.85023

Jochems J, Boulden J, Lee BG, Blendy JA, Jarpe M, Mazitschek R, Van Duzer JH, Berton O

Antidepressant-Like Properties of Novel HDAC6 Selective Inhibitors with Improved Brain Bioavailability. Neuropsychopharmacology. 2013;39(2):389-400 - PMID: 23954848 - PMCID: PMC3870780 - DOI: 10.1038/npp.2013.207

Gerosa L, Chidley C, Fröhlich F, Sanchez G, Lim SK, Muhlich J, Chen JY, Vallabhaneni S, Baker GJ, Schapiro D, Atanasova MI, Chylek LA, Shi T, Yi L, Nicora CD, Claas A, Ng TSC, Kohler RH, Lauffenburger DA, Weissleder R, Miller MA, Qian WJ, Wiley HS, Sorger PK

Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells. Cell Syst. 2020;11(5):478-494.e9 - PMID: 33113355 - PMCID: PMC8009031 - DOI: 10.1016/j.cels.2020.10.002

Miller MA, Arlauckas S, Weissleder R

Prediction of Anti-cancer Nanotherapy Efficacy by Imaging Nanotheranostics. 2017;1(3):296-312 - PMID: 29071194 - PMCID: PMC5646731 - DOI: 10.7150/ntno.20564

Arlauckas S, Oh N, Li R, Weissleder R, Miller MA

Macrophage imaging and subset analysis using single-cell RNA sequencing. Nanotheranostics. 2021;5(1):36-56 - PMID: 33391974 - PMCID: PMC7738942 - DOI: 10.7150/ntno.50185

Choy E, Yelensky R, Bonakdar S, Plenge RM, Saxena R, De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C, Rivas M, Dermitzakis ET, Cahir-McFarland E, Kieff E, Hafler D, Daly MJ, Altshuler D

Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines PLoS Genet. 2008;4(11):e1000287 - PMID: 19043577 - PMCID: PMC2583954 - DOI: 10.1371/journal.pgen.1000287

Ku M, Koche R, Rheinbay E, Mendenhall E, Endoh M, Mikkelsen T, Presser A, Nusbaum C, Xie X, Chi A, Adli M, Kasif S, Ptaszek L, Cowan C, Lander E, Koseki H, Bernstein B

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet. 2008;4(10):e1000242 - PMID: 18974828 - PMCID: PMC2567431 - DOI: 10.1371/journal.pgen.1000242

Mendenhall EM, Koche RP, Truong T, Zhou VW, Issac B, Chi AS, Ku M, Bernstein BE

GC-Rich Sequence Elements Recruit PRC2 in Mammalian ES Cells. PLoS Genet. 2010;6(12):e1001244 - PMID: 21170310 - PMCID: PMC3000368 - DOI: 10.1371/journal.pgen.1001244

Ziller MJ, Müller F, Liao J, Zhang Y, Gu H, Bock C, Boyle P, Epstein CB, Bernstein BE, Lengauer T, Gnirke A, Meissner A

Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types. PLoS Genet. 2011;7(12):e1002389 - PMID: 22174693 - PMCID: PMC3234221 - DOI: 10.1371/journal.pgen.1002389

Endoh M, Endo TA, Endoh T, Isono K, Sharif J, Ohara O, Toyoda T, Ito T, Eskeland R, Bickmore WA, Vidal M, Bernstein BE, Koseki H

Histone H2A Mono-Ubiquitination Is a Crucial Step to Mediate PRC1-Dependent Repression of Developmental Genes to Maintain ES Cell Identity. PLoS Genet. 2012;8(7):e1002774 - PMID: 22844243 - PMCID: PMC3405999 - DOI: 10.1371/journal.pgen.1002774

Ferder IC, Fung L, Ohguchi Y, Zhang X, Lassen KG, Capen D, Brown D, Xavier RJ, Wang N

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice. PLoS Genet. 2019;15(5):e1008084 - PMID: 31059511 - PMCID: PMC6502318 - DOI: 10.1371/journal.pgen.1008084

Viaud S, Daillère R, Boneca IG, Lepage P, Langella P, Chamaillard M, Pittet MJ, Ghiringhelli F, Trinchieri G, Goldszmid R, Zitvogel L

Gut microbiome and anticancer immune response: really hot Sh*t! Cell Death Differ. 2014;22(2):199-214 - PMID: 24832470 - PMCID: PMC4291500 - DOI: 10.1038/cdd.2014.56

Shtatland T, Gill S, Javornik B, Johansson H, Singer B, Uhlenbeck O, Zichi D, Gold L

Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. Nucleic Acids Res. 2000;28:E93 - PMID: 11058143 - PMCID: PMC113162 - DOI: 10.1093/nar/28.21.e93

Singer B, Shtatland T, Brown D, Gold L

Libraries for genomic SELEX. Nucleic Acids Res. 1997;25:781-6 - PMID: 9016629 - PMCID: PMC146522 - DOI: 10.1093/nar/25.4.781

Abrams E, Shtatland T, Lerman L

PCR assay for a polymorphic TaqI site in the human K-ras-2 gene on chromosome 12p (KRAS2). Nucleic Acids Res. 1991;19:4795 - PMID: 1679926 - PMCID: PMC328755 - DOI: 10.1093/nar/19.17.4795

Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites. Nucleic Acids Res. 2013;41(19):e181 - PMID: 23945932 - PMCID: PMC3799455 - DOI: 10.1093/nar/gkt716

Brown CR, Gupta S, Qin J, Racie T, He G, Lentini S, Malone R, Yu M, Matsuda S, Shulga-Morskaya S, Nair AV, Theile CS, Schmidt K, Shahraz A, Goel V, Parmar RG, Zlatev I, Schlegel MK, Nair JK, Jayaraman M, Manoharan M, Brown D, Maier MA, Jadhav V

Investigating the pharmacodynamic durability of GalNAc-siRNA conjugates. Nucleic Acids Res. 2020;48(21):11827-11844 - PMID: 32808038 - PMCID: PMC7708070 - DOI: 10.1093/nar/gkaa670

Babitt JL, Lin HY

The molecular pathogenesis of hereditary hemochromatosis. Semin Liver Dis. 2011;31(3):280-92 - PMID: 21901658 - DOI: 10.1055/s-0031-1286059

Pittet MJ, Garris CS, Arlauckas SP, Weissleder R

Recording the wild lives of immune cells. Sci Immunol. 2018;3(27):ePub - PMID: 30194240 - PMCID: PMC6771424 - DOI: 10.1126/sciimmunol.aaq0491

Calcagno DM, Ng RP, Toomu A, Zhang C, Huang K, Aguirre AD, Weissleder R, Daniels LB, Fu Z, King KR

Type I interferon responses to ischemic injury begin in the bone marrow of mice and humans and depend on Tet2, Nrf2, and Irf3 Sci Immunol. 2020;5(51):ePub - PMID: 32978242 - PMCID: PMC7808338 - DOI: 10.1126/sciimmunol.aaz1974

Siwicki M, Gort-Freitas NA, Messemaker M, Bill R, Gungabeesoon J, Engblom C, Zilionis R, Garris C, Gerhard GM, Kohl A, Lin Y, Zou AE, Cianciaruso C, Bolli E, Pfirschke C, Lin YJ, Piot C, Mindur JE, Talele N, Kohler RH, Iwamoto Y, Mino-Kenudson M, Pai SI, deVito C, Koessler T, Merkler D, Coukos A, Wicky A, Fraga M, Sempoux C, Jain RK, Dietrich PY, Michielin O, Weissleder R, Klein AM, Pittet MJ

Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy. Sci Immunol. 2021;6(61):eabi7083 - PMID: 34215680 - PMCID: PMC8845079 - DOI: 10.1126/sciimmunol.abi7083

Adamson RJ, Payne NC, Bartual SG, Mazitschek R, Bullock AN

Structural and biochemical characterization establishes a detailed understanding of KEAP1-CUL3 complex assembly. Free Radic Biol Med. 2023;204:215-225 - PMID: 37156295 - PMCID: PMC10564622 - DOI: 10.1016/j.freeradbiomed.2023.04.021

Malka R, Brugnara C, Cialic R, Higgins JM

Non-Parametric Combined Reference Regions and Prediction of Clinical Risk. Clin Chem. 2020;66(2):363-372 - PMID: 32040586 - PMCID: PMC7055670 - DOI: 10.1093/clinchem/hvz020

Pittet M, Swirski F, Reynolds F, Josephson L, Weissleder R.

Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles Nat Protoc. 2006;1(1):73-79 - PMID: 17406214 - DOI: 10.1038/nprot.2006.11

Lo Celso C, Lin CP, Scadden DT

In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow. Nat Protoc. 2010;6(1):1-14 - PMID: 21212779 - PMCID: PMC3382040 - DOI: 10.1038/nprot.2010.168

Adli M, Bernstein BE

Whole-genome chromatin profiling from limited numbers of cells using nano-ChIP-seq. Nat Protoc. 2011;6(10):1656-68 - PMID: 21959244 - PMCID: PMC4493313 - DOI: 10.1038/nprot.2011.402

Vinegoni C, Aguirre AD, Lee S, Weissleder R

Imaging the beating heart in the mouse using intravital microscopy techniques. Nat Protoc. 2015;10(11):1802-1819 - PMID: 26492138 - PMCID: PMC5380003 - DOI: 10.1038/nprot.2015.119

Vinegoni C, Fumene Feruglio P, Brand C, Lee S, Nibbs AE, Stapleton S, Shah S, Gryczynski I, Reiner T, Mazitschek R, Weissleder R

Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging. Nat Protoc. 2017;12(7):1472-1497 - PMID: 28686582 - PMCID: PMC5928516 - DOI: 10.1038/nprot.2017.043

Chen J, Landegger LD, Sun Y, Ren J, Maimon N, Wu L, Ng MR, Chen JW, Zhang N, Zhao Y, Gao X, Fujita T, Roberge S, Huang P, Jain RK, Plotkin SR, Stankovic KM, Xu L

A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma. Nat Protoc. 2019;14(2):541-555 - PMID: 30617350 - PMCID: PMC6571021 - DOI: 10.1038/s41596-018-0105-7

Bremer C, Mustafa M, Bogdanov A Jr, Ntziachristos V, Petrovsky A, Weissleder R

Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice Radiology. 2003;226:214-20 - PMID: 12511693 - DOI: 10.1148/radiol.2261012140

Mahmood U, Tung CH, Tang Y, Weissleder R

Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice Radiology. 2002;224:446-51 - PMID: 12147841 - DOI: 10.1148/radiol.2242011589

Bremer C, Tung CH, Bogdanov A Jr, Weissleder R

Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes Radiology. 2002;222:814-8 - PMID: 11867806 - DOI: 10.1148/radiol.2223010812

Weissleder R, Mahmood U

Molecular imaging Radiology. 2001;219:316-33 - PMID: 11323453 - DOI: 10.1148/radiology.219.2.r01ma19316

Moore A, Josephson L, Bhorade RM, Basilion JP, Weissleder R

Human transferrin receptor gene as a marker gene for MR imaging Radiology. 2001;221:244-50 - PMID: 11568347 - DOI: 10.1148/radiol.2211001784

Bremer C, Bredow S, Mahmood U, Weissleder R, Tung CH

Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model Radiology. 2001;221:523-9 - PMID: 11687699 - DOI: 10.1148/radiol.2212010368

Moore A, Marecos E, Bogdanov A Jr, Weissleder R

Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model Radiology. 2000;214:568-74 - PMID: 10671613 - DOI: 10.1148/radiology.214.2.r00fe19568

Weissleder R

Molecular imaging: exploring the next frontier Radiology. 1999;212:609-14 - PMID: 10478223 - DOI: 10.1148/radiology.212.3.r99se18609

Mahmood U, Tung CH, Bogdanov A Jr, Weissleder R

Near-infrared optical imaging of protease activity for tumor detection Radiology. 1999;213:866-70 - PMID: 10580968 - DOI: 10.1148/radiology.213.3.r99dc14866

Funovics MA, Weissleder R, Mahmood U

Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 2004;231(3):659-66 - PMID: 15163807 - DOI: 10.1148/radiol.2313030831

Mahmood U

Can MR Imaging Be Used to Track Delivery of Intravascularly Administered Stem Cells? Radiology. 2004;233(3):625-6 - PMID: 15564396 - DOI: 10.1148/radiol.2333041190

Chen JW, Querol Sans M, Bogdanov Jr A, Weissleder R

Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates Radiology. 2006;240 (2):473-81 - PMID: 16864673 - DOI: 10.1148/radiol.2402050994

Mahmood U

Can a clinically used chemoembolization vehicle improve transgene delivery? Radiology. 2006;240(3):619-20 - PMID: 16926318 - DOI: 10.1148/radiol.2403060761

Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D

Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by using Real-time Bioluminescent Imaging. Radiology. 2006;241(3):822-830 - PMID: 17114629 - DOI: 10.1148/radiol.2413050466

Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R.

Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007;242 (3):751-758 - PMID: 17325064 - DOI: 10.1148/radiol.2423052065

Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U

Colonic Adenocarcinomas: Near-Infrared Microcatheter Imaging of Smart Probes for Early Detection. Radiology. 2007;244(1):232-8 - PMID: 17507718 - DOI: 10.1148/radiol.2441052114

Upadhyay R, Sheth RA, Weissleder R, Mahmood U

Quantitative Real-time Catheter-based Fluorescence Molecular Imaging in Mice. Radiology. 2007;245(2):523-31 - PMID: 17940307 - DOI: 10.1148/radiol.2452061613

Nahrendorf M, Hiller K, Theisen D, Hu K, Waller C, Kaiser R, Haase A, Ertl G, Brinkmann R, Bauer W

Effect of transmyocardial laser revascularization on myocardial perfusion and left ventricular remodeling after myocardial infarction in rats. Radiology. 2002;225(2):487-93 - PMID: 12409584 - DOI: 10.1148/radiol.2252011325

Goldberg M, Gazelle G, Boland G, Hahn P, Mayo-Smith W, Pivovarov M, Halpern E, Wittenberg J

Focal hepatic lesions: effect of three-dimensional wavelet compression on detection at CT. Radiology. 1997;202:159-65 - PMID: 8988206 - DOI: 10.1148/radiology.202.1.8988206

Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U

Human Breast Cancer Tumor Models: Molecular Imaging of Drug Susceptibility and Dosing during HER2/neu-targeted Therapy. Radiology. 2008;248(3):925-35 - PMID: 18647846 - PMCID: PMC2798096 - DOI: 10.1148/radiol.2482071496

Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schar M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M

Off-Resonance Angiography: A New Method to Depict Vessels--Phantom and Rabbit Studies. Radiology. 2008;249(2)::501-509 - PMID: 18780823 - PMCID: PMC2657865 - DOI: 10.1148/radiol.2491071706

Sosnovik DE

Will molecular MR imaging play a role in identification and treatment of patients with vulnerable atherosclerotic plaques? Radiology. 2009;251:309-10 - PMID: 19401565 - DOI: 10.1148/radiol.2512090268

Sheth RA, Tam JM, Maricevich MA, Josephson L, Mahmood U

Quantitative Endovascular Fluorescence-based Molecular Imaging through Blood of Arterial Wall Inflammation. Radiology. 2009;251(3):813-21 - PMID: 19474377 - PMCID: PMC2687531 - DOI: 10.1148/radiol.2513081450

Pandharipande PV, Gervais DA, Hartman RI, Harisinghani MG, Feldman AS, Mueller PR, Gazelle GS

Renal Mass Biopsy to Guide Treatment Decisions for Small Incidental Renal Tumors: A Cost-effectiveness Analysis. Radiology. 2010;256(3):836-46 - PMID: 20720070 - PMCID: PMC2923731 - DOI: 10.1148/radiol.10092013

de Marco G, Bogdanov A, Marecos E, Moore A, Simonova M, Weissleder R

MR imaging of gene delivery to the central nervous system with an artificial vector. Radiology. 1998;208(1):65-71 - PMID: 9646794 - DOI: 10.1148/radiology.208.1.9646794

Weissleder R, Simonova M, Bogdanova A, Bredow S, Enochs WS, Bogdanov A

MR imaging and scintigraphy of gene expression through melanin induction. Radiology. 1997;204(2):425-9 - PMID: 9240530 - DOI: 10.1148/radiology.204.2.9240530

Enochs WS, Petherick P, Bogdanova A, Mohr U, Weissleder R

Paramagnetic metal scavenging by melanin: MR imaging. Radiology. 1997;204(2):417-23 - PMID: 9240529 - DOI: 10.1148/radiology.204.2.9240529

Harisinghani MG, Saini S, Weissleder R, Halpern EF, Schima W, Rubin DL, Stillman AE, Sica GT, Small WC, Hahn PF

Differentiation of liver hemangiomas from metastases and hepatocellular carcinoma at MR imaging enhanced with blood-pool contrast agent Code-7227. Radiology. 1997;202(3):687-91 - PMID: 9051017 - DOI: 10.1148/radiology.202.3.9051017

Harika L, Weissleder R, Poss K, Papisov MI

Macromolecular intravenous contrast agent for MR lymphography: characterization and efficacy studies. Radiology. 1996;198(2):365-70 - PMID: 8596833 - DOI: 10.1148/radiology.198.2.8596833

Gupta H, Wilkinson RA, Bogdanov AA, Callahan RJ, Weissleder R

Inflammation: imaging with methoxy poly(ethylene glycol)-poly-L-lysine-DTPA, a long-circulating graft copolymer. Radiology. 1995;197(3):665-9 - PMID: 7480736 - DOI: 10.1148/radiology.197.3.7480736

Zimmer C, Weissleder R, Poss K, Bogdanova A, Wright SC, Enochs WS

MR imaging of phagocytosis in experimental gliomas. Radiology. 1995;197(2):533-8 - PMID: 7480707 - DOI: 10.1148/radiology.197.2.7480707

Zimmer C, Weissleder R, O'Connor D, LaPointe L, Brady TJ, Enochs WS

Cerebral iron oxide distribution: in vivo mapping with MR imaging. Radiology. 1995;196(2):521-7 - PMID: 7617871 - DOI: 10.1148/radiology.196.2.7617871

Gupta H, Weissleder R, Bogdanov AA, Brady TJ

Experimental gastrointestinal hemorrhage: detection with contrast-enhanced MR imaging and scintigraphy. Radiology. 1995;196(1):239-44 - PMID: 7784574 - DOI: 10.1148/radiology.196.1.7784574

Weissleder R

Liver MR imaging with iron oxides: toward consensus and clinical practice. Radiology. 1994;193(3):593-5 - PMID: 7972790 - DOI: 10.1148/radiology.193.3.7972790

Reimer P, Weissleder R, Shen T, Knoefel WT, Brady TJ

Pancreatic receptors: initial feasibility studies with a targeted contrast agent for MR imaging. Radiology. 1994;193(2):527-31 - PMID: 7972773 - DOI: 10.1148/radiology.193.2.7972773

van Everdingen KJ, Enochs WS, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R

Determinants of in vivo MR imaging of slow axonal transport. Radiology. 1994;193(2):485-91 - PMID: 7526413 - DOI: 10.1148/radiology.193.2.7526413

Weissleder R, Heautot JF, Schaffer BK, Nossiff N, Papisov MI, Bogdanov A, Brady TJ

MR lymphography: study of a high-efficiency lymphotrophic agent. Radiology. 1994;191(1):225-30 - PMID: 8134576 - DOI: 10.1148/radiology.191.1.8134576

Bogdanov AA, Weissleder R, Frank HW, Bogdanova AV, Nossif N, Schaffer BK, Tsai E, Papisov MI, Brady TJ

A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology. 1993;187(3):701-6 - PMID: 8497616 - DOI: 10.1148/radiology.187.3.8497616

Reimer P, Weissleder R, Wittenberg J, Brady TJ

Receptor-directed contrast agents for MR imaging: preclinical evaluation with affinity assays. Radiology. 1992;182(2):565-9 - PMID: 1732982 - DOI: 10.1148/radiology.182.2.1732982

Weissleder R, Lee AS, Khaw BA, Shen T, Brady TJ

Antimyosin-labeled monocrystalline iron oxide allows detection of myocardial infarct: MR antibody imaging. Radiology. 1992;182(2):381-5 - PMID: 1732953 - DOI: 10.1148/radiology.182.2.1732953

Weissleder R, Lee AS, Fischman AJ, Reimer P, Shen T, Wilkinson R, Callahan RJ, Brady TJ

Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging. Radiology. 1991;181(1):245-9 - PMID: 1887040 - DOI: 10.1148/radiology.181.1.1887040

Reimer P, Weissleder R, Brady TJ, Yeager AE, Baldwin BH, Tennant BC, Wittenberg J

Experimental hepatocellular carcinoma: MR receptor imaging. Radiology. 1991;180(3):641-5 - PMID: 1871273 - DOI: 10.1148/radiology.180.3.1871273

Seneterre E, Weissleder R, Jaramillo D, Reimer P, Lee AS, Brady TJ, Wittenberg J

Bone marrow: ultrasmall superparamagnetic iron oxide for MR imaging. Radiology. 1991;179(2):529-33 - PMID: 2014305 - DOI: 10.1148/radiology.179.2.2014305

Reimer P, Weissleder R, Lee AS, Buettner S, Wittenberg J, Brady TJ

Asialoglycoprotein receptor function in benign liver disease: evaluation with MR imaging. Radiology. 1991;178(3):769-74 - PMID: 1994416 - DOI: 10.1148/radiology.178.3.1994416

Lee AS, Weissleder R, Brady TJ, Wittenberg J

Lymph nodes: microstructural anatomy at MR imaging. Radiology. 1991;178(2):519-22 - PMID: 1987619 - DOI: 10.1148/radiology.178.2.1987619

Reimer P, Weissleder R, Lee AS, Wittenberg J, Brady TJ

Receptor imaging: application to MR imaging of liver cancer. Radiology. 1990;177(3):729-34 - PMID: 2243978 - DOI: 10.1148/radiology.177.3.2243978

Hahn PF, Stark DD, Lewis JM, Saini S, Elizondo G, Weissleder R, Fretz CJ, Ferrucci JT

First clinical trial of a new superparamagnetic iron oxide for use as an oral gastrointestinal contrast agent in MR imaging. Radiology. 1990;175(3):695-700 - PMID: 2343116 - DOI: 10.1148/radiology.175.3.2343116

Weissleder R, Elizondo G, Wittenberg J, Lee AS, Josephson L, Brady TJ

Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology. 1990;175(2):494-8 - PMID: 2326475 - DOI: 10.1148/radiology.175.2.2326475

Weissleder R, Elizondo G, Wittenberg J, Rabito CA, Bengele HH, Josephson L

Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging. Radiology. 1990;175(2):489-93 - PMID: 2326474 - DOI: 10.1148/radiology.175.2.2326474

Elizondo G, Weissleder R, Stark DD, Guerra J, Garza J, Fretz CJ, Todd LE, Ferrucci JT

Hepatic cirrhosis and hepatitis: MR imaging enhanced with superparamagnetic iron oxide. Radiology. 1990;174(3 Pt 1):797-801 - PMID: 2305063 - DOI: 10.1148/radiology.174.3.2305063

Hahn PF, Stark DD, Weissleder R, Elizondo G, Saini S, Ferrucci JT

Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology. 1990;174(2):361-6 - PMID: 2296646 - DOI: 10.1148/radiology.174.2.2296646

Fretz CJ, Elizondo G, Weissleder R, Hahn PF, Stark DD, Ferrucci JT

Superparamagnetic iron oxide-enhanced MR imaging: pulse sequence optimization for detection of liver cancer. Radiology. 1989;172(2):393-7 - PMID: 2748820 - DOI: 10.1148/radiology.172.2.2748820

Weissleder R, Thrall JH

The lymphatic system: diagnostic imaging studies. Radiology. 1989;172(2):315-7 - PMID: 2748809 - DOI: 10.1148/radiology.172.2.2748809

Weissleder R, Elizondo G, Josephson L, Compton CC, Fretz CJ, Stark DD, Ferrucci JT

Experimental lymph node metastases: enhanced detection with MR lymphography. Radiology. 1989;171(3):835-9 - PMID: 2717761 - DOI: 10.1148/radiology.171.3.2717761

Dousset M, Weissleder R, Hendrick RE, Stark DD, Fretz CJ, Elizondo G, Hahn PF, Saini S, Ferrucci JT

Short TI inversion-recovery imaging of the liver: pulse-sequence optimization and comparison with spin-echo imaging. Radiology. 1989;171(2):327-33 - PMID: 2704797 - DOI: 10.1148/radiology.171.2.2704797

Rummeny E, Weissleder R, Sironi S, Stark DD, Comptom CC, Hahn PF, Saini S, Wittenberg J, Ferrucci JT

Central scars in primary liver tumors: MR features, specificity, and pathologic correlation. Radiology. 1989;171(2):323-6 - PMID: 2539605 - DOI: 10.1148/radiology.171.2.2539605

Weissleder H, Weissleder R

Interstitial lymphangiography: initial clinical experience with a dimeric nonionic contrast agent. Radiology. 1989;170(2):371-4 - PMID: 2911660 - DOI: 10.1148/radiology.170.2.2911660

Weissleder R, Hahn PF, Stark DD, Elizondo G, Saini S, Todd LE, Wittenberg J, Ferrucci JT

Superparamagnetic iron oxide: enhanced detection of focal splenic tumors with MR imaging. Radiology. 1988;169(2):399-403 - PMID: 3174987 - DOI: 10.1148/radiology.169.2.3174987

Stark DD, Weissleder R, Elizondo G, Hahn PF, Saini S, Todd LE, Wittenberg J, Ferrucci JT

Superparamagnetic iron oxide: clinical application as a contrast agent for MR imaging of the liver. Radiology. 1988;168(2):297-301 - PMID: 3393649 - DOI: 10.1148/radiology.168.2.3393649

Weissleder H, Weissleder R

Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology. 1988;167(3):729-35 - PMID: 3363131 - DOI: 10.1148/radiology.167.3.3363131

Tsang YM, Stark DD, Chen MC, Weissleder R, Wittenberg J, Ferrucci JT

Hepatic micrometastases in the rat: ferrite-enhanced MR imaging. Radiology. 1988;167(1):21-4 - PMID: 3347724 - DOI: 10.1148/radiology.167.1.3347724

Weissleder R, Stark DD, Rummeny EJ, Compton CC, Ferrucci JT

Splenic lymphoma: ferrite-enhanced MR imaging in rats. Radiology. 1988;166(2):423-30 - PMID: 3336717 - DOI: 10.1148/radiology.166.2.3336717

Elizondo G, Weissleder R, Stark DD, Todd LE, Compton C, Wittenberg J, Ferrucci JT

Amebic liver abscess: diagnosis and treatment evaluation with MR imaging. Radiology. 1987;165(3):795-800 - PMID: 2891154 - DOI: 10.1148/radiology.165.3.2891154

Waller C, Kahler E, Hiller KH, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer WR

Myocardial perfusion and intracapillary blood volume in rats at rest and with coronary dilatation: MR imaging in vivo with use of a spin-labeling technique. Radiology. 2000;215(1):189-97 - PMID: 10751486 - DOI: 10.1148/radiology.215.1.r00ap07189

Nahrendorf M, Sosnovik DE

Science to practice: will magnetic guidance of microbubbles play a role in clinical molecular imaging? Radiology. 2011;260(2):309-10 - PMID: 21778448 - DOI: 10.1148/radiol.11111017

Su HS, Nahrendorf M, Panizzi PR, Breckwoldt MO, Rodriguez E, Iwamoto Y, Aikawa E, Weissleder R, Chen JW

Vasculitis: Molecular Imaging by Targeting the Inflammatory Enzyme Myeloperoxidase. Radiology. 2011;262(1):181-90 - PMID: 22084204 - PMCID: PMC3244672 - DOI: 10.1148/radiol.11110040

Forghani R, Wojtkiewicz GR, Zhang Y, Seeburg D, Bautz BR, Pulli B, Milewski AR, Atkinson WL, Iwamoto Y, Zhang ER, Etzrodt M, Rodriguez E, Robbins CS, Swirski FK, Weissleder R, Chen JW

Demyelinating Diseases: Myeloperoxidase as an Imaging Biomarker and Therapeutic Target. Radiology. 2012;263(2):451-60 - PMID: 22438365 - PMCID: PMC3329272 - DOI: 10.1148/radiol.12111593

Sosnovik DE, Nahrendorf M, Caravan P

Science to Practice: How Will Myocardial Inflammation Be Imaged with MR Imaging? Radiology. 2012;264(2):309-11 - PMID: 22821689 - PMCID: PMC6939999 - DOI: 10.1148/radiol.12121094

Pulli B, Bure L, Wojtkiewicz GR, Iwamoto Y, Ali M, Li D, Schob S, Li-Chun Hsieh K, Jacobs AH, Chen JW

Multiple Sclerosis: Myeloperoxidase Immunoradiology Improves Detection of Acute and Chronic Disease in Experimental Model. Radiology. 2014;275(2):480-9 - PMID: 25494298 - PMCID: PMC4455671 - DOI: 10.1148/radiol.14141495

Zhang Y, Seeburg DP, Pulli B, Wojtkiewicz GR, Bure L, Atkinson W, Schob S, Iwamoto Y, Ali M, Zhang W, Rodriguez E, Milewski A, Keliher EJ, Wang C, Pan Y, Swirski FK, Chen JW

Myeloperoxidase Nuclear Imaging for Epileptogenesis. Radiology. 2015;278(3):822-30 - PMID: 26397127 - PMCID: PMC4770943 - DOI: 10.1148/radiol.2015141922

Albadawi H, Chen JW, Oklu R, Wu Y, Wojtkiewicz G, Pulli B, Milner JD, Cambria RP, Watkins MT

Spinal Cord Inflammation: Molecular Imaging after Thoracic Aortic Ischemia Reperfusion Injury. Radiology. 2016;282(1):202-211 - PMID: 27509542 - PMCID: PMC5207124 - DOI: 10.1148/radiol.2016152222

Pulli B, Wojtkiewicz G, Iwamoto Y, Ali M, Zeller MW, Bure L, Wang C, Choi Y, Masia R, Guimaraes AR, Corey KE, Chen JW

Molecular MR Imaging of Myeloperoxidase Distinguishes Steatosis from Steatohepatitis in Nonalcoholic Fatty Liver Disease. Radiology. 2017;284(2):390-400 - PMID: 28358240 - PMCID: PMC5548451 - DOI: 10.1148/radiol.2017160588

Hoffmann A, Pfeil J, Mueller AK, Jin J, Deumelandt K, Helluy X, Wang C, Heiland S, Platten M, Chen JW, Bendszus M, Breckwoldt MO

MRI of Iron Oxide Nanoparticles and Myeloperoxidase Activity Links Inflammation to Brain Edema in Experimental Cerebral Malaria. Radiology. 2018;290(2):359-367 - PMID: 30615566 - DOI: 10.1148/radiol.2018181051

Li A, Wu Y, Pulli B, Wojtkiewicz GR, Iwamoto Y, Wang C, Li JH, Ali M, Feng X, Yao Z, Chen JW

Myeloperoxidase Molecular MRI Reveals Synergistic Combination Therapy in Murine Experimental Autoimmune Neuroinflammation. Radiology. 2019;293(1):158-165 - PMID: 31478802 - PMCID: PMC6776885 - DOI: 10.1148/radiol.2019182492

Ng TSC, Gunda V, Li R, Prytyskach M, Iwamoto Y, Kohler RH, Parangi S, Weissleder R, Miller MA

Detecting Immune Response to Therapies Targeting PDL1 and BRAF by Using Ferumoxytol MRI and Macrin in Anaplastic Thyroid Cancer Radiology. 2020;298(1):123-132 - PMID: 33107799 - PMCID: PMC7771993 - DOI: 10.1148/radiol.2020201791

Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD

The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int. 2007;71(6):504-13 - PMID: 17228368 - DOI: 10.1038/sj.ki.5002041

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Controversies in nephrology: Response to ''renal albumin handling, facts, and artifacts'' Kidney Int. 2007;72(10):1195-7 - PMID: 17851467 - DOI: 10.1038/sj.ki.5002528

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Response to ''Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique'' Kidney Int. 2007;72:1411 - PMID: 18004315

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Response to ''On the origin of albuminuria'' Kidney Int. 2007;72:1409-10 - PMID: 18004312

Gutierrez O, Lin H

Refractory hyponatremia. Kidney Int. 2007;71(1):79-82 - PMID: 16985516 - DOI: 10.1038/sj.ki.5001845

Zalyapin EA, Bouley R, Hasler U, Vilardaga JP, Lin HY, Brown D, Ausiello DA

Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling. Kidney Int. 2008;74(12):1557-67 - PMID: 18813286 - PMCID: PMC3730289 - DOI: 10.1038/ki.2008.412

Miller RL, Lucero OM, Riemondy KA, Baumgartner BK, Brown D, Breton S, Nelson RD

The V-ATPase B1-subunit promoter drives expression of Cre recombinase in intercalated cells of the kidney. Kidney Int. 2008;75(4):435-9 - PMID: 19052537 - PMCID: PMC4301582 - DOI: 10.1038/ki.2008.569

Miranda KC, Bond DT, McKee M, Skog J, Paunescu TG, Da Silva N, Brown D, Russo LM

Nucleic acids within urinary exosomes/microvesicles are potential biomarkers for renal disease. Kidney Int. 2010;78(2):191-9 - PMID: 20428099 - PMCID: PMC4451567 - DOI: 10.1038/ki.2010.106

Schreiner R, Frindt G, Diaz F, Carvajal-Gonzalez JM, Perez Bay AE, Palmer LG, Marshansky V, Brown D, Philp NJ, Rodriguez-Boulan E

The absence of a clathrin adapter confers unique polarity essential to proximal tubule function. Kidney Int. 2010;78(4):382-8 - PMID: 20531453 - PMCID: PMC3684398 - DOI: 10.1038/ki.2010.166

Brown D, Breton S

Sorting proteins to their target membranes. Kidney Int. 2000;57(3):816-24 - PMID: 10720934 - DOI: 10.1046/j.1523-1755.2000.00920.x

Bouley R

Corin: a key protein of an adaptive renal mechanism to respond to salt variation? Kidney Int. 2012;82(1):7-8 - PMID: 22699378 - DOI: 10.1038/ki.2012.123

Huang J, McKee M, Huang HD, Xiang A, Davidson AJ, Lu HA

A zebrafish model of conditional targeted podocyte ablation and regeneration. Kidney Int. 2013;83(6):1193-200 - PMID: 23466998 - PMCID: PMC3672345 - DOI: 10.1038/ki.2013.6

David V, Martin A, Isakova T, Spaulding C, Qi L, Ramirez V, Zumbrennen-Bullough KB, Sun CC, Lin HY, Babitt JL, Wolf M

Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production. Kidney Int. 2016;89(1):135-46 - PMID: 26535997 - PMCID: PMC4854810 - DOI: 10.1038/ki.2015.290

Sise ME, Wisocky J, Rosales IA, Chute D, Holmes JA, Corapi KM, Babitt JL, Tangren JS, Hashemi N, Lundquist AL, Williams WW, Mount DB, Andersson KL, Rennke HG, Smith RN, Colvin R, Thadhani RI, Chung RT

Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy. Kidney Int. 2016;1(3):135-143 - PMID: 27990496 - PMCID: PMC5155703 - DOI: 10.1016/j.ekir.2016.06.006

Bourgeois S, Bounoure L, Mouro-Chanteloup I, Colin Y, Brown D, Wagner CA

The ammonia transporter RhCG modulates urinary acidification by interacting with the vacuolar proton-ATPases in renal intercalated cells. Kidney Int. 2017;93(2):390-402 - PMID: 29054531 - PMCID: PMC6166241 - DOI: 10.1016/j.kint.2017.07.027

Moore A, Bonner-Weir S, Weissleder R

Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes Diabetes. 2001;50:2231-6 - PMID: 11574403 - DOI: 10.2337/diabetes.50.10.2231

Russo LM, del Re E, Brown D, Lin HY

Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor. Diabetes. 2007;56(2):380-8 - PMID: 17259382 - DOI: 10.2337/db06-1018

Cameron-Vendrig A, Reheman A, Siraj MA, Xu XR, Wang Y, Lei X, Afroze T, Shikatani E, El-Mounayri O, Noyan H, Weissleder R, Ni H, Husain M

Glucagon-like peptide-1 receptor activation attenuates platelet aggregation and thrombosis. Diabetes. 2016;65(6):1714-23 - PMID: 26936963 - DOI: 10.2337/db15-1141

Cruz DN, Perazella MA, Bellomo R, de Cal M, Polanco N, Corradi V, Lentini P, Nalesso F, Ueno T, Ranieri VM, Ronco C

Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review. Crit Care. 2008;11(2):R47 - PMID: 17448226 - PMCID: PMC2206475 - DOI: 10.1186/cc5780

McCarthy J, Jaffer F, Weissleder R.

A Macrophage Targeted Theranostic Nanoparticle for Biomedical Applications Small. 2006;2(8-9):983-987 - PMID: 17193154 - DOI: 10.1002/smll.200600139

Sun EY, Weissleder R, Josephson L.

Continuous Analyte Sensing with Magnetic Nanoswitches Small. 2006;(2) 10:1144-1147 - PMID: 17193579 - DOI: 10.1002/smll.200600204

McCarthy JR, Korngold E, Weissleder R, Jaffer FA

A Light-Activated Theranostic Nanoagent for Targeted Macrophage Ablation in Inflammatory Atherosclerosis. Small. 2010;6(18):2041-9 - PMID: 20721949 - PMCID: PMC3018665 - DOI: 10.1002/smll.201000596

Agasti SS, Kohler RH, Liong M, Peterson VM, Lee H, Weissleder R

Dual Imaging and Photoactivated Nanoprobe for Controlled Cell Tracking. Small. 2012;9(2):222-7 - PMID: 22996932 - PMCID: PMC3552149 - DOI: 10.1002/smll.201201007

Liu R, Rallo R, Weissleder R, Tassa C, Shaw S, Cohen Y

Nano-SAR Development for Bioactivity of Nanoparticles with Considerations of Decision Boundaries. Small. 2013;9(9-10):1842-52 - PMID: 23423856 - DOI: 10.1002/smll.201201903

Im H, Oh SH

Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges. Small. 2013;10(4):680-4 - PMID: 24123889 - DOI: 10.1002/smll.201301475

Koo H, Choi M, Kim E, Hahn SK, Weissleder R, Yun SH

Bioorthogonal Click Chemistry-Based Synthetic Cell Glue. Small. 2015;11(48):6458-66 - PMID: 26768353 - PMCID: PMC5556392 - DOI: 10.1002/smll.201502972

Im H, Oh SH

Oxidation sharpening, template stripping, and passivation of ultra-sharp metallic pyramids and wedges. Small. 2013;10(4):680-4 - PMID: 24123889 - DOI: 10.1002/smll.201301475

Hennings JC, Picard N, Huebner AK, Stauber T, Maier H, Brown D, Jentsch TJ, Vargas-Poussou R, Eladari D, Hübner CA

A mouse model for distal renal tubular acidosis reveals a previously unrecognized role of the V-ATPase a4 subunit in the proximal tubule. EMBO Mol Med. 2012;4(10):1057-71 - PMID: 22933323 - PMCID: PMC3491836 - DOI: 10.1002/emmm.201201527

Meyer IS, Jungmann A, Dieterich C, Zhang M, Lasitschka F, Werkmeister S, Haas J, Müller OJ, Boutros M, Nahrendorf M, Katus HA, Hardt SE, Leuschner F

The cardiac microenvironment uses non-canonical WNT signaling to activate monocytes after myocardial infarction. EMBO Mol Med. 2017;9(9):1279-1293 - PMID: 28774883 - PMCID: PMC5582413 - DOI: 10.15252/emmm.201707565

Hingtgen SD, Kasmieh R, van de Water J, Weissleder R, Shah K

Determining Multiple Aspects of Stem Cell-Based Therapies Using Novel Diagnostic and Therapeutic Multifunctional Molecules. Stem Cells. 2010;28(4):832-41 - PMID: 20127797 - PMCID: PMC3021283 - DOI: 10.1002/stem.313

Teo GS, Yang Z, Carman CV, Karp JM, Lin CP

Intravital Imaging of Mesenchymal Stem Cell Trafficking and Association with Platelets and Neutrophils. Stem Cells. 2015;33(1):265-277 - PMID: 25263183 - PMCID: PMC4270897 - DOI: 10.1002/stem.1848

Dykstra B, Lee J, Mortensen LJ, Yu H, Wu ZL, Lin CP, Rossi DJ, Sackstein R

Glycoengineering of E-selectin ligands by intracellular versus extracellular fucosylation differentially affects osteotropism of human mesenchymal stem cells. Stem Cells. 2016;34(10):2501-2511 - PMID: 27335219 - PMCID: PMC5064874 - DOI: 10.1002/stem.2435

Hewett J, Nery F, Niland B, Ge P, Tan P, Hadwiger P, Tannous B, Sah D, Breakefield X

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells. Hum Mol Genet. 2008;17:1436-45 - PMID: 18258738 - PMCID: PMC2861568 - DOI: 10.1093/hmg/ddn032

Reis SA, Thompson MN, Lee JM, Fossale E, Kim HH, Liao JK, Moskowitz MA, Shaw SY, Dong L, Haggarty SJ, Macdonald ME, Seong IS

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis. Hum Mol Genet. 2011;20(12):2344-55 - PMID: 21447599 - PMCID: PMC3098733 - DOI: 10.1093/hmg/ddr127

Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H

Impaired Hepcidin Expression in Alpha-1-Antitrypsin Deficiency Associated with Iron Overload and Progressive Liver Disease. Hum Mol Genet. 2015;24(21):6254-63 - PMID: 26310624 - PMCID: PMC4599680 - DOI: 10.1093/hmg/ddv348

Morini E, Dietrich P, Salani M, Downs HM, Wojtkiewicz GR, Alli S, Brenner A, Nilbratt M, LeClair JW, Oaklander AL, Slaugenhaupt SA, Dragatsis I

Sensory and autonomic deficits in a new humanized mouse model of familial dysautonomia. Hum Mol Genet. 2016;25(6):1116-28 - PMID: 26769677 - PMCID: PMC4764193 - DOI: 10.1093/hmg/ddv634

Pulli B, Ali M, Iwamoto Y, Zeller MW, Schob S, Linnoila JJ, Chen JW

Myeloperoxidase - Hepatocyte - Stellate Cell Crosstalk Promotes Hepatocyte Injury and Fibrosis in Experimental NASH. Antioxid Redox Signal. 2015;23(16):1255-1269 - PMID: 26058518 - PMCID: PMC4677570 - DOI: 10.1089/ars.2014.6108

Lauriol J, Keith K, Jaffré F, Couvillon A, Saci A, Goonasekera SA, McCarthy JR, Kessinger CW, Wang J, Ke Q, Kang PM, Molkentin JD, Carpenter C, Kontaridis MI

RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis. Sci Signal. 2014;7(348):ra100 - PMID: 25336613 - PMCID: PMC4300109 - DOI: 10.1126/scisignal.2005262

Meyer AS, Miller MA, Gertler FB, Lauffenburger DA

The receptor AXL diversifies EGFR signaling and limits the response to EGFR-targeted inhibitors in triple-negative breast cancer cells. Sci Signal. 2013;6(287):ra66 - PMID: 23921085 - PMCID: PMC3947921 - DOI: 10.1126/scisignal.2004155

McCarthy J, Kelly KA, Sun EY, Weissleder R.

Targeted delivery of multifunctional magnetic nanoparticles Nanomedicine. 2007;2(2):153-167 - PMID: 17716118 - DOI: 10.2217/17435889.2.2.153

Martinez-Boubeta C, Balcells L, Cristool R, Sanfeliu C, Rodriguez E, Weissleder R, Lope-Piedrafita S, Simeonidis K, Angelakeris M, Sandiumenge F, Calleja A, Casas L, Monty C, Martinez B

Self-assembled Multifunctional Fe/MgO Nanospheres for Magnetic Resonance Imaging and Hyperthermia. Nanomedicine. 2009;6(2):362-370 - PMID: 19800988 - DOI: 10.1016/j.nano.2009.09.003

McCarthy JR

The future of theranostic nanoagents. Nanomedicine. 2009;4(7):693-5 - PMID: 19839803 - DOI: 10.2217/nnm.09.58

Ghazani A, Pectasides M, Sharma A, Castro CM, Mino-Kenudson M, Lee H, Shepard JA, Weissleder R

Molecular characterization of scant lung tumor cells using iron-oxide nanoparticles and micro-nuclear magnetic resonance. Nanomedicine. 2013;10 :661-668 - PMID: 24200523 - PMCID: PMC3966960 - DOI: 10.1016/j.nano.2013.10.008

Gee MS, Ghazani AA, Haq R, Wargo JA, Sebas M, Sullivan RJ, Lee H, Weissleder R

Point of care assessment of melanoma tumor signaling and metastatic burden from μNMR analysis of tumor fine needle aspirates and peripheral blood. Nanomedicine. 2016;13(3):821-828 - PMID: 27993725 - PMCID: PMC5392428 - DOI: 10.1016/j.nano.2016.12.006

Jiménez-Dinamarca I, Prado Y, Tapia P, Gatica S, Alt C, Lin CP, Reyes-Martínez C, Feijóo CG, Aravena C, González-Canacer A, Correa S, Varela D, Cabello-Verrugio C, Simon F

Disseminated intravascular coagulation phenotype is regulated by the TRPM7 channel during sepsis. Biol Res. 2023;56(1):8 - PMID: 36869357 - PMCID: PMC9983216 - DOI: 10.1186/s40659-023-00419-4

Jiménez-Dinamarca I, Prado Y, Tapia P, Gatica S, Alt C, Lin CP, Reyes-Martínez C, Feijóo CG, Aravena C, González-Canacer A, Correa S, Varela D, Cabello-Verrugio C, Simon F

Correction: Disseminated intravascular coagulation phenotype is regulated by the TRPM7 channel during sepsis. Biol Res. 2023;56(1):24 - PMID: 37165417 - PMCID: PMC10173557 - DOI: 10.1186/s40659-023-00433-6

Engelmayr G, Rabkin E, Sutherland F, Schoen F, Mayer J, Sacks M

The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue. Biomaterials . 2005;26:175-87 - PMID: 15207464 - DOI: 10.1016/j.biomaterials.2004.02.035

Ramaswamy S, Gottlieb D, Engelmayr GC, Aikawa E, Schmidt DE, Gaitan-Leon DM, Sales VL, Mayer JE, Sacks MS

The role of organ level conditioning on the promotion of engineered heart valve tissue development in-vitro using mesenchymal stem cells. Biomaterials . 2009;31(6):1114-25 - PMID: 19944458 - PMCID: PMC2813971 - DOI: 10.1016/j.biomaterials.2009.10.019

Kraehenbuehl TP, Ferreira LS, Hayward AM, Nahrendorf M, van der Vlies AJ, Vasile E, Weissleder R, Langer R, Hubbell JA

Human embryonic stem cell-derived microvascular grafts for cardiac tissue preservation after myocardial infarction. Biomaterials . 2010;32(4):1102-9 - PMID: 21035182 - PMCID: PMC6805145 - DOI: 10.1016/j.biomaterials.2010.10.005

Cheng H, Byrska-Bishop M, Zhang CT, Kastrup CJ, Hwang NS, Tai AK, Lee WW, Xu X, Nahrendorf M, Langer R, Anderson DG

Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell-selectin interaction kinetics. Biomaterials . 2012;33(20):5004-12 - PMID: 22494889 - PMCID: PMC3366278 - DOI: 10.1016/j.biomaterials.2012.03.065

Desai RM, Koshy ST, Hilderbrand SA, Mooney DJ, Joshi NS

Versatile click alginate hydrogels crosslinked via tetrazine-norbornene chemistry. Biomaterials . 2015;50:30-7 - PMID: 25736493 - DOI: 10.1016/j.biomaterials.2015.01.048

Wright ME, Yu JK, Jain D, Maeda A, Yeh SA, DaCosta RS, Lin CP, Santerre JP

Engineering functional microvessels in synthetic polyurethane random-pore scaffolds by harnessing perfusion flow. Biomaterials . 2020;256:120183 - PMID: 32622017 - DOI: 10.1016/j.biomaterials.2020.120183

Im H, Wittenberg NJ, Lesuffleur A, Lindquist NC, Oh SH

Membrane protein biosensing with plasmonic nanopore arrays and pore-spanning lipid membranes. Chem Sci. 2010;1(6):688-696 - PMID: 21218136 - PMCID: PMC3015192 - DOI: 10.1039/C0SC00365D

Timms L, Zhou T, Qiao J, Gharagouzloo C, Mishra V, Lahoud RM, Chen JW, Harisinghani M, Sridhar S

Super High Contrast USPIO-Enhanced Cerebrovascular Angiography Using Ultrashort Time-to-Echo MRI. Int J Biomed Imaging. 2024;2024:9763364 - PMID: 38644981 - PMCID: PMC11032209 - DOI: 10.1155/2024/9763364

Ng TSC, Liu M, Robertson M, Könik A, Cheng SC, Bakht MK, Harrington K, Wolanski A, Gilbert L, Preston M, Mossanen M, Beltran H, Hirsch MS, Sonpavde G, Jacene HA

A pilot study of [18F]F-fluciclovine positron emission tomography/computed tomography for staging muscle invasive bladder cancer preceding radical cystectomy. Eur J Nucl Med Mol Imaging. 2025;52(11):4092-4101 - PMID: 40257614 - DOI: 10.1007/s00259-025-07287-y

Amako Y, Ichikawa S, Lloyd HC, Payne NC, Lin Z, Boghossian AS, Rees MG, Ronan MM, Roth JA, Zhu Q, Budnik B, Mazitschek R, Woo CM

The contribution of cyclic imide stereoisomers on cereblon-dependent activity. Chem Sci. 2025;16(25):11519-11529 - PMID: 40443985 - PMCID: PMC12117711 - DOI: 10.1039/d5sc01371b

Borges N, Losee M, Liu M, Cheng SC, Könik A, Ritzer J, Wolanski A, Ng TSC, Choudhury AD, Taplin ME, Ravi P, Jacene H

Effect of bone marrow disease on hematologic toxicity and response to [177Lu]Lu-PSMA-617 therapy: insights from PSMA-PET/CT imaging. Eur J Nucl Med Mol Imaging. 2025;:ePub - PMID: 40908334 - DOI: 10.1007/s00259-025-07541-3

Courties G, Moskowitz MA, Nahrendorf M

The Innate Immune System After Ischemic Injury: Lessons to Be Learned From the Heart and Brain. JAMA Neurol. 2014;71(2):233-6 - PMID: 24296962 - PMCID: PMC3946050 - DOI: 10.1001/jamaneurol.2013.5026

Demers M, Sturtevant S, Guertin KR, Gupta D, Desai K, Vieira BF, Li W, Hicks A, Ismail A, Gonçalves BP, Di Caprio G, Schonbrun E, Hansen S, Musayev FN, Safo MK, Wood DK, Higgins JM, Light DR

MetAP2 inhibition modifies hemoglobin S to delay polymerization and improves blood flow in sickle cell disease. Blood Adv. 2021;5(5):1388-1402 - PMID: 33661300 - PMCID: PMC7948285 - DOI: 10.1182/bloodadvances.2020003670

Foy B, Stefely J, Bendapudi PK, Hasserjian RP, Al-Samkari H, Louissaint A, Fitzpatrick M, Hutchison B, Mow C, Collins J, Patel H, Patel C, Patel N, Ho S, Kaufman RM, Dzik W', Higgins JM, Makar RS

Computer vision quantitation of erythrocyte shape abnormalities provides diagnostic, prognostic, and mechanistic insight. Blood Adv. 2023;7(16):4621-4630 - PMID: 37146262 - PMCID: PMC10448422 - DOI: 10.1182/bloodadvances.2022008967

Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy S, Boitano A, Nahrendorf M, Scadden DT

Clearing and replacing tissue-resident myeloid cells with an anti-CD45-antibody-drug conjugate. Blood Adv. 2023;7(22):6964-6973 - PMID: 37748049 - PMCID: PMC10690556 - DOI: 10.1182/bloodadvances.2023010561

Sosnovik DE, Weissleder R

Emerging concepts in molecular MRI. Curr Opin Biotech. 2007;18(1):4-10 - PMID: 17126545 - DOI: 10.1016/j.copbio.2006.11.001

Wunder A, Tung CH, Muller-Ladner U, Weissleder R, Mahmood U

In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arth Rheum/AR C Res. 2004;50(8):2459-65 - PMID: 15334458 - DOI: 10.1002/art.20379

Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arth Rheum/AR C Res. 2007;56(1):117-128 - PMID: 17195214 - DOI: 10.1002/art.22303

Mendenhall E, Bernstein B

Chromatin state maps: new technologies, new insights. Curr Opin Genet Dev. 2008;18(2):109-15 - PMID: 18339538 - PMCID: PMC2486450 - DOI: 10.1016/j.gde.2008.01.010

Khazaie K, von Boehmer H

The impact of CD4(+)CD25(+) Treg on tumor specific CD8(+) T cell cytotoxicity and cancer. Semin Cancer Biol. 2006;16(2):124-136 - PMID: 16443370 - DOI: 10.1016/j.semcancer.2005.11.006

Speiser D, Pittet M, Rimoldi D, Guillaume P, Luescher I, Lienard D, Lejeune F, Cerottini J, Romero P

Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. Semin Cancer Biol. 2003;13:461-72 - PMID: 15001165 - DOI: 10.1016/j.semcancer.2003.09.010

Jijon HB, Suarez-Lopez L, Diaz OE, Das S, De Calisto J, Yaffe MB, Pittet MJ, Mora JR, Belkaid Y, Xavier RJ, Villablanca EJ

Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system. Mucosal Immunol. 2017;11(3):703-715 - PMID: 29139475 - PMCID: PMC5953762 - DOI: 10.1038/mi.2017.91

Shah K, Tang Y, Breakefield X, Weissleder R

Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo Oncogene. 2003;22:6865-72 - PMID: 14534533 - DOI: 10.1038/sj.onc.1206748

van Eekelen M, Sasportas LS, Kasmieh R, Yip S, Figueiredo JL, Louis DN, Weissleder R, Shah K

Human stem cells expressing novel TSP-1 variant have anti-angiogenic effect on brain tumors. Oncogene. 2010;29(22):3185-95 - PMID: 20305695 - PMCID: PMC3390229 - DOI: 10.1038/onc.2010.75

Aranda F, Bloy N, Pesquet J, Petit B, Chaba K, Sauvat A, Kepp O, Khadra N, Enot D, Pfirschke C, Pittet M, Zitvogel L, Kroemer G, Senovilla L

Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer. Oncogene. 2014;34(23):3053-62 - PMID: 25065595 - DOI: 10.1038/onc.2014.234

Helman E, Naxerova K, Kohane IS

DNA hypermethylation in lung cancer is targeted at differentiation-associated genes. Oncogene. 2011;31(9):1181-8 - PMID: 21804601 - DOI: 10.1038/onc.2011.307

Trink B, Pai SI, Spunt SL, Raman V, Cairns P, Jen J, Gabrielson E, Sukumar S, Sidransky D

Absence of TSG101 transcript abnormalities in human cancers. Oncogene. 1998;16(21):2815-8 - PMID: 9652749 - DOI: 10.1038/sj.onc.1201795

Linnoila J, Jalali Motlagh N, Jachimiec G, Lin CJ, Küllenberg E, Wojtkiewicz G, Tanzi R, Chen JW

Optimizing animal models of autoimmune encephalitis using active immunization. Front Immunol. 2023;14:1177672 - PMID: 37520559 - PMCID: PMC10374403 - DOI: 10.3389/fimmu.2023.1177672

Sarkar B, Arlauckas SP, Cuccarese MF, Garris CS, Weissleder R, Rodell CB

Host-functionalization of macrin nanoparticles to enable drug loading and control tumor-associated macrophage phenotype Frontiers in Immunology (molecular innate immunity section). 2024;15:1331480 - PMID: 38545103 - PMCID: PMC10965546 - DOI: 10.3389/fimmu.2024.1331480

King K, Grazette LP, Paltoo DN, McDevitt JT, Sia SK, Barrett PM, Apple FS, Gurbel PA, Weissleder R, Leeds H, Iturriaga EJ, Rao A, Adhikari B, Desvigne-Nickens P, Galis ZS, Libby P

Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group. JACC Basic Transl Sci. 2016;1(1-2):73-86 - PMID: 26977455 - PMCID: PMC4787294 - DOI: 10.1016/j.jacbts.2016.01.008

She A, Kurtser I, Reis SA, Hennig K, Lai J, Lang A, Zhao WN, Mazitschek R, Dickerson BC, Herz J, Haggarty SJ

Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal Dementia. Cell Chem Biol. 2017;24(7):892-906.e5 - PMID: 28712747 - PMCID: PMC5695697 - DOI: 10.1016/j.chembiol.2017.06.010

Ali M, Pulli B, Courties G, Tricot B, Sebas M, Iwamoto Y, Hilgendorf I, Schob S, Dong A, Zheng W, Skoura A, Kalgukar A, Cortes C, Ruggeri R, Swirski FK, Nahrendorf M, Buckbinder L, Chen JW

Myeloperoxidase Inhibition Improves Ventricular Function and Remodeling After Experimental Myocardial Infarction JACC Basic Transl Sci. 2016;1(7):633-643 - PMID: 30167547 - PMCID: PMC6113523 - DOI: 10.1016/j.jacbts.2016.09.004

Koch PD, Rodell CB, Kohler RH, Pittet MJ, Weissleder R

Myeloid Cell-Targeted Nanocarriers Efficiently Inhibit Cellular Inhibitor of Apoptosis for Cancer Immunotherapy. Cell Chem Biol. 2020;27(1):94-104.e5 - PMID: 31902676 - PMCID: PMC7422681 - DOI: 10.1016/j.chembiol.2019.12.007

Payne NC, Mazitschek R

Resolving the deceptive isoform and complex selectivity of HDAC1/2 inhibitors. Cell Chem Biol. 2022;29(7):1140-1152.e5 - PMID: 35298895 - DOI: 10.1016/j.chembiol.2022.03.002

Payne NC, Maksoud S, Tannous BA, Mazitschek R

A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader. Cell Chem Biol. 2022;29(8):1333-1340.e5 - PMID: 35649410 - PMCID: PMC9391279 - DOI: 10.1016/j.chembiol.2022.05.003

Maier A, Toner YC, Munitz J, Sullivan NAT, Sakurai K, Meerwaldt AE, Brechbühl EES, Prévot G, van Elsas Y, Maas RJF, Ranzenigo A, Soultanidis G, Rashidian M, Pérez-Medina C, Heo GS, Gropler RJ, Liu Y, Reiner T, Nahrendorf M, Swirski FK, Strijkers GJ, Teunissen AJP, Calcagno C, Fayad ZA, Mulder WJM, van Leent MMT

Multiparametric Immunoimaging Maps Inflammatory Signatures in Murine Myocardial Infarction Models. JACC Basic Transl Sci. 2023;8(7):801-816 - PMID: 37547068 - PMCID: PMC10401290 - DOI: 10.1016/j.jacbts.2022.12.014

Gopal AA, Fernandez B, Delano J, Weissleder R, Dubach JM

PARP trapping is governed by the PARP inhibitor dissociation rate constant. Cell Chem Biol. 2024;31(7):1373-1382.e10 - PMID: 38262416 - PMCID: PMC11259578 - DOI: 10.1016/j.chembiol.2023.12.019

Ichikawa S, Payne NC, Xu W, Chang CF, Vallavoju N, Frome S, Flaxman HA, Mazitschek R, Woo CM

The cyclimids: Degron-inspired cereblon binders for targeted protein degradation. Cell Chem Biol. 2024;31(6):1162-1175.e10 - PMID: 38320555 - PMCID: PMC12136240 - DOI: 10.1016/j.chembiol.2024.01.003

Antolin AA, Aye Y, Bar-Peled L, De Vita E, Dudkina N, Jewett MC, Kiely-Collins H, Mazitschek R, Zhang ZJ

What is chemical biology? Cell Chem Biol. 2024;31(9):1562-1565 - PMID: 39303695 - DOI: 10.1016/j.chembiol.2024.08.011

Lloyd HC, Li Y, Payne NC, Zhao Z, Xu W, Kroupova A, Zollman D, Long T, Kabir F, Chen M, Freeman R, Feng EY, Xi SY, Hsu YC, Ciulli A, Mazitschek R, Woo CM

A method for the detection and enrichment of endogenous cereblon substrates. Cell Chem Biol. 2025;32(8):1028-1041.e13 - PMID: 40782806 - PMCID: PMC12360616 - DOI: 10.1016/j.chembiol.2025.07.002

Nahrendorf M

Recognizing Early Career Translational Investigators. JACC Basic Transl Sci. 2025;10(8):101362 - PMID: 40866044 - PMCID: PMC12399141 - DOI: 10.1016/j.jacbts.2025.101362

Nahrendorf M

Unleashing the Power of the Beehive to Begin a New Era for JACC: Basic to Translational Science. JACC Basic Transl Sci. 2025;10(8):101360 - PMID: 40866039 - PMCID: PMC12399142 - DOI: 10.1016/j.jacbts.2025.101360

Kumowski N, Nahrendorf M

On Macrophage Culture. JACC Basic Transl Sci. 2025;10(9):101375 - PMID: 40992828 - PMCID: PMC12539482 - DOI: 10.1016/j.jacbts.2025.101375

Bopp S, Fagbami L, Deik A, Taccheri C, Pant A, Luth M, Chen D, Tye MA, Ullah I, Kreuzer J, Morris R, Haas W, Winzeler EA, Clish C, Lukens AK, Mazitschek R, Wirth DF

Disruption of P. falciparum amino acid transporter elevates intracellular proline and induces resistance to Prolyl-tRNA synthetase inhibitors. Cell Chem Biol. 2025;32(10):1293-1302.e5 - PMID: 41061700 - DOI: 10.1016/j.chembiol.2025.09.007

Nahrendorf M

Recognizing Early Career Translational Investigators. JACC Basic Transl Sci. 2025;10(10):101398 - PMID: 41161898 - PMCID: PMC12665410 - DOI: 10.1016/j.jacbts.2025.101398

Ferreira AV, Nahrendorf M

Metabolic Memory Resides in the Hematopoietic Marrow and in Arterial Resident Leukocytes. JACC Basic Transl Sci. 2025;10(10):101392 - PMID: 41161897 - PMCID: PMC12665419 - DOI: 10.1016/j.jacbts.2025.101392

Nahrendorf M

Recognizing Early Career Translational Investigators. JACC Basic Transl Sci. 2025;10(11):101410 - PMID: 41298046 - DOI: 10.1016/j.jacbts.2025.101410

Nahrendorf M, Kumowski N, Steffens S

Neutrophils in Myocardial Infarction. JACC Basic Transl Sci. 2025;10(11):101408 - PMID: 41298044 - DOI: 10.1016/j.jacbts.2025.101408

Novobrantseva TI, Borodovsky A, Wong J, Klebanov B, Zafari M, Yucius K, Querbes W, Ge P, Ruda VM, Milstein S, Speciner L, Duncan R, Barros S, Basha G, Cullis P, Akinc A, Donahoe JS, Narayanannair Jayaprakash K, Jayaraman M, Bogorad RL, Love K, Whitehead K, Levins C, Manoharan M, Swirski FK, Weissleder R, Langer R, Anderson DG, de Fougerolles A, Nahrendorf M, Koteliansky V

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells. Mol Ther Nucleic Acids. 2012;1:e4 - PMID: 23344621 - PMCID: PMC3381593 - DOI: 10.1038/mtna.2011.3

Ko J, Wang Y, Carlson JCT, Marquard A, Gungabeesoon J, Charest A, Weitz D, Pittet MJ, Weissleder R

Single Extracellular Vesicle Protein Analysis Using Immuno- Droplet Digital Polymerase Chain Reaction Amplification Adv Biosyst. 2020;:ePub - DOI: 10.1002/adbi.201900307

Van Deun J, Jo A, Li H, Lin HY, Weissleder R, Im H, Lee H

Integrated Dual-Mode Chromatography to Enrich Extracellular Vesicles from Plasma. Adv Biosyst. 2020;4(12):e1900310 - PMID: 32351054 - PMCID: PMC7606548 - DOI: 10.1002/adbi.201900310

Ferguson S, Weissleder R

Modeling EV Kinetics for Use in Early Cancer Detection Adv Biosyst. 2020;4(12):e1900305 - PMID: 32394646 - PMCID: PMC7658022 - DOI: 10.1002/adbi.201900305

Min J, Son T, Hong JS, Cheah PS Wegemann A, Murlidharan K, Weissleder R, Lee H, Im H

Plasmon-Enhanced Biosensing for Multiplexed Profiling of Extracellular Vesicles Adv Biosyst. 2020;2020:2000003 - PMID: 32815321 - PMCID: PMC7718316 - DOI: 10.1002/adbi.202000003 - Cover

Yang KS, Lin HY, Curley C, Welch MW, Wolpin BM, Lee H, Weissleder R, Im H*, Castro CM*

Bead-Based Extracellular Vesicle Analysis Using Flow Cytometry. Adv Biosyst. 2020;4(12):e2000203 - PMID: 33103361 - PMCID: PMC7718389 - DOI: 10.1002/adbi.202000203

Ko J, Wang Y, Carlson JCT, Marquard A, Gungabeesoon J, Charest A, Weitz D, Pittet MJ, Weissleder R

Single Extracellular Vesicle Protein Analysis Using Immuno-Droplet Digital Polymerase Chain Reaction Amplification. Adv Biosyst. 2020;4(12):e1900307 - PMID: 33274611 - PMCID: PMC8491538 - DOI: 10.1002/adbi.201900307

Weissleder R

The Magical World of Circulating Vesicles. Adv Biosyst. 2020;4(12):e2000475 - PMID: 33274610 - DOI: 10.1002/adbi.202000475

Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO.

Codon-optimized gaussia luciferase cDNA for Mammalian gene expression in culture and in vivo Mol Ther. 2005;11(3):435-43 - PMID: 15727940 - DOI: 10.1016/j.ymthe.2004.10.016

Shah K, Tung CH, Breakefield X, Weissleder R.

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis Mol Ther. 2005;11 (6):926-931 - PMID: 15922963 - DOI: 10.1016/j.ymthe.2005.01.017

Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA

Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging. Mol Ther. 2006;4(6):779-88 - PMID: 16996314 - PMCID: PMC2819149 - DOI: 10.1016/j.ymthe.2006.08.008

Hamed HA, Yacoub A, Park MA, Eulitt PJ, Dash R, Sarkar D, Dmitriev IP, Lesniak MS, Shah K, Grant S, Curiel DT, Fisher PB, Dent P

Inhibition of Multiple Protective Signaling Pathways and Ad.5/3 Delivery Enhances mda-7/IL-24 Therapy of Malignant Glioma. Mol Ther. 2010;18(6):1130-42 - PMID: 20179672 - PMCID: PMC2889737 - DOI: 10.1038/mt.2010.29

Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL

Bevacizumab With Angiostatin-armed oHSV Increases Antiangiogenesis and Decreases Bevacizumab-induced Invasion in U87 Glioma. Mol Ther. 2011;20(1):37-45 - PMID: 21915104 - PMCID: PMC3255598 - DOI: 10.1038/mt.2011.187

Noh KH, Kang TH, Kim JH, Pai SI, Lin KY, Hung CF, Wu TC, Kim TW

Activation of Akt as a mechanism for tumor immune evasion. Mol Ther. 2008;17(3):439-47 - PMID: 19107122 - PMCID: PMC2835083 - DOI: 10.1038/mt.2008.255

Filz von Reiterdank I, Bento R, Dinicu AT, Taveras C, Hassan M, Mojoudi M, Chen H, Ellis BW, Wojtkiewicz G, Weissleder R, Uygun BE, Cetrulo CL, Coert JH, Mink van der Molen AB, Parekkadan B, Uygun K

Genetically Engineered Organs for Early Reporting of Transplant Rejection. Mol Ther. 2025;:ePub - PMID: 41088753 - DOI: 10.1016/j.ymthe.2025.10.024

Wilk K, Yeh SA, Mortensen LJ, Ghaffarigarakani S, Lombardo CM, Bassir SH, Aldawood ZA, Lin CP, Intini G

Postnatal Calvarial Skeletal Stem Cells Expressing PRX1 Reside Exclusively in the Calvarial Sutures and Are Required for Bone Regeneration. Stem Cell Reports. 2017;8(4):933-946 - PMID: 28366454 - PMCID: PMC5390237 - DOI: 10.1016/j.stemcr.2017.03.002

Godlewski J, Ferrer-Luna R, Rooj AK, Mineo M, Ricklefs F, Takeda YS, Nowicki MO, Salińska E, Nakano I, Lee H, Weissleder R, Beroukhim R, Chiocca EA, Bronisz A

MicroRNA Signatures and Molecular Subtypes of Glioblastoma: The Role of Extracellular Transfer. Stem Cell Reports. 2017;8(6):1497-1505 - PMID: 28528698 - PMCID: PMC5470095 - DOI: 10.1016/j.stemcr.2017.04.024

Liu CL, Liu X, Wang Y, Deng Z, Liu T, Sukhova GK, Wojtkiewicz GR, Tang R, Zhang JY, Achilefu S, Nahrendorf M, Libby P, Wang X, Shi GP

Reduced Nhe1 (Na+-H+ Exchanger-1) Function Protects ApoE-Deficient Mice From Ang II (Angiotensin II)-Induced Abdominal Aortic Aneurysms. Hypertension. 2020;76(1):87-100 - PMID: 32475310 - PMCID: PMC7289683 - DOI: 10.1161/HYPERTENSIONAHA.119.14485

Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R.

Mapping of nodal disease in locally advanced prostate cancer: Rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy Int J Radiat Oncol Biol Phys. 2005;63(4):1262-9 - PMID: 16253781 - DOI: 10.1016/j.ijrobp.2005.07.952

Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG

Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2009;74(4):1207-16 - PMID: 19545786 - PMCID: PMC2733223 - DOI: 10.1016/j.ijrobp.2009.02.052

Macdonald SM, Harisinghani MG, Katkar A, Napolitano B, Wolfgang J, Taghian AG

Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer. Int J Radiat Oncol Biol Phys. 2009;77(4):1098-104 - PMID: 19836160 - DOI: 10.1016/j.ijrobp.2009.06.002

Kirsch DG, Grimm J, Guimaraes AR, Wojtkiewicz GR, Perez BA, Santiago PM, Anthony NK, Forbes T, Doppke K, Weissleder R, Jacks T

Imaging Primary Lung Cancers in Mice to Study Radiation Biology. Int J Radiat Oncol Biol Phys. 2010;76(4):973-977 - PMID: 20206017 - PMCID: PMC2847457 - DOI: 10.1016/j.ijrobp.2009.11.038

Kirsch DG, Grimm J, Guimaraes AR, Weissleder R

In response to dr. Garbow and colleagues. Int J Radiat Oncol Biol Phys. 2011;79(3):959 - PMID: 21281902

Mahmood U, Bang A, Chen YH, Mak RH, Lorch JH, Hanna GJ, Nishino M, Manuszak C, Thrash EM, Severgnini M, Sanborn M, Sridharan V, Margalit DN, Tishler RB, Busse PM, Willers H, Mamon HJ, Yoo HJ, Pai SI, Wirth LJ, Haddad RI, Chau NG, Schoenfeld JD

A Randomized Phase 2 Study of Pembrolizumab With or Without Radiation in Patients With Recurrent or Metastatic Adenoid Cystic Carcinoma. Int J Radiat Oncol Biol Phys. 2020;109(1):134-144 - PMID: 32781104 - PMCID: PMC9361179 - DOI: 10.1016/j.ijrobp.2020.08.018

Hwang WL, Su J, Shiau C, Wang PL, Guo JA, Lester NA, Barth JL, Hoffman HI, Aguirre A, Hong TS, Wo JY, Ting D, Zheng L, Mino-Kenudson M, Jacks T

Molecular Mechanisms of Intratumoral Nerve Recruitment and Perineural Invasion Elucidated with Spatial Transcriptomics and CRISPR Activation. Int J Radiat Oncol Biol Phys. 2023;117(2S):S21 - PMID: 37784453 - DOI: 10.1016/j.ijrobp.2023.06.244

Banla LI, Hwang WL, Willers H

The R's of Radiation Therapy: Do We Need More or Do We Move On? Int J Radiat Oncol Biol Phys. 2024;119(3):734-736 - PMID: 38851274 - DOI: 10.1016/j.ijrobp.2024.02.008

Motlagh NJ, Wang C, Kim HH, Jun Y, Kim D, Lee S, Chen JW

Aging Intensifies Myeloperoxidase Activity after Ischemic Stroke. Aging Dis. 2024;15(6):2650-2664 - PMID: 39325942 - PMCID: PMC11567251 - DOI: 10.14336/AD.2023.1640

Breton S, Brown D

Regulation of Luminal Acidification by the V-ATPase. Physiology (Bethesda). 2013;28(5):318-29 - PMID: 23997191 - PMCID: PMC3768094 - DOI: 10.1152/physiol.00007.2013

Reckelhoff JF, Brown D, Molina PE

APS Takes a Look in the Mirror. Physiology (Bethesda). 2016;31(6):384-385 - PMID: 27708041 - DOI: 10.1152/physiol.00023.2016

Brown D, Sands JM, Reckelhoff JF

APS: The Times They Are A-Changin'. Physiology (Bethesda). 2017;32(6):400-401 - PMID: 28978629 - DOI: 10.1152/physiol.00025.2017

Sands JM, Hay M, Brown D

APS: Moving Forward to Aid Our Membership. Physiology (Bethesda). 2018;33(6):370-371 - PMID: 30303777 - DOI: 10.1152/physiol.00039.2018

Basilion JP, Yeon S, Botnar R

Magnetic Resonance Imaging: Utility as a Molecular Imaging Modality. Curr Top Dev Biol. 2005;70(c):1-33 - PMID: 16338335 - DOI: 10.1016/S0070-2153(05)70001-6

Gros J, Hu JK, Vinegoni C, Feruglio PF, Weissleder R, Tabin CJ

WNT5A/JNK and FGF/MAPK Pathways Regulate the Cellular Events Shaping the Vertebrate Limb Bud. Curr Top Dev Biol. 2010;20(22):1993-2002 - PMID: 21055947 - PMCID: PMC2998074 - DOI: 10.1016/j.cub.2010.09.063

Mahmood U, Josephson L

Molecular MR Imaging Probes P IEEE. 0;93 (4):800-808

Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R

Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008;28:4406-13 - PMID: 18434519 - PMCID: PMC3021321 - DOI: 10.1523/JNEUROSCI.0296-08.2008

Samad T, Srinivasan A, Karchewski L, Jeong S, Campagna J, Ji R, Fabrizio D, Zhang Y, Lin HY, Bell E, Woolf C

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci. 2004;24(8):2027-36 - PMID: 14985445 - PMCID: PMC6730385 - DOI: 10.1523/JNEUROSCI.4115-03.2004

Ma CH, Brenner GJ, Omura T, Samad OA, Costigan M, Inquimbert P, Niederkofler V, Salie R, Sun CC, Lin HY, Arber S, Coppola G, Woolf CJ, Samad TA

The BMP Coreceptor RGMb Promotes While the Endogenous BMP Antagonist Noggin Reduces Neurite Outgrowth and Peripheral Nerve Regeneration by Modulating BMP Signaling. J Neurosci. 2011;31(50):18391-18400 - PMID: 22171041 - PMCID: PMC3243947 - DOI: 10.1523/JNEUROSCI.4550-11.2011

Paly JJ, Efstathiou JA, Hedgire SS, Chung PW, O'Malley M, Shah A, Bekelman JE, Harisinghani M, Shipley WU, Zietman AL, Beard C

Mapping patterns of nodal metastases in seminoma: Rethinking radiotherapy fields. Radiother Oncol. 2013;106(1):64-8 - PMID: 23321493 - DOI: 10.1016/j.radonc.2012.12.002

Yuan Y, Andronesi OC, Bortfeld TR, Richter C, Wolf R, Guimaraes AR, Hong TS, Seco J

Feasibility study of in vivo MRI based dosimetric verification of proton end-of-range for liver cancer patients. Radiother Oncol. 2013;106(3):378-82 - PMID: 23473960 - DOI: 10.1016/j.radonc.2013.01.016

Niyazi M, Niemierko A, Paganetti H, Söhn M, Schapira E, Goldberg S, Adams J, Kim V, Oh KS, Hwang WL, Lu HM, Belka C, Busse PM, Loeffler JS, Shih HA

Volumetric and actuarial analysis of brain necrosis in proton therapy using a novel mixture cure model. Radiother Oncol. 2019;142:154-161 - PMID: 31563411 - DOI: 10.1016/j.radonc.2019.09.008

Holzschuh JC, Mix M, Ruf J, Hölscher T, Kotzerke J, Vrachimis A, Doolan P, Ilhan H, Marinescu IM, Spohn SKB, Fechter T, Kuhn D, Bronsert P, Gratzke C, Grosu R, Kamran SC, Heidari P, Ng TSC, Könik A, Grosu AL, Zamboglou C

Deep Learning based Automated Delineation of the Intraprostatic Gross Tumour Volume in PSMA-PET for Patients with Primary Prostate Cancer. Radiother Oncol. 2023;188:109774 - PMID: 37394103 - PMCID: PMC10862258 - DOI: 10.1016/j.radonc.2023.109774

Etzrodt M, Cortez-Retamozo V, Newton A, Zhao J, Ng A, Wildgruber M, Romero P, Wurdinger T, Xavier RJ, Geissmann F, Meylan E, Nahrendorf M, Swirski FK, Baltimore D, Weissleder R, Pittet MJ

Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb Cell Rep. 2012;1(4):1-8 - PMID: 22545247 - PMCID: PMC3334310 - DOI: 10.1016/j.celrep.2012.02.009

Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W

Inhibitory Effects of Robo2 on Nephrin: A Crosstalk between Positive and Negative Signals Regulating Podocyte Structure. Cell Rep. 2012;2(1):52-61 - PMID: 22840396 - PMCID: PMC3627357 - DOI: 10.1016/j.celrep.2012.06.002

Mak AB, Nixon AM, Kittanakom S, Stewart JM, Chen GI, Curak J, Gingras AC, Mazitschek R, Neel BG, Stagljar I, Moffat J

Regulation of CD133 by HDAC6 Promotes β-Catenin Signaling to Suppress Cancer Cell Differentiation. Cell Rep. 2012;2(4):951-63 - PMID: 23084749 - PMCID: PMC3590846 - DOI: 10.1016/j.celrep.2012.09.016

Rheinbay E, Suvà ML, Gillespie SM, Wakimoto H, Patel AP, Shahid M, Oksuz O, Rabkin SD, Martuza RL, Rivera MN, Louis DN, Kasif S, Chi AS, Bernstein BE

An Aberrant Transcription Factor Network Essential for Wnt Signaling and Stem Cell Maintenance in Glioblastoma. Cell Rep. 2013;3(5):1567-1579 - PMID: 23707066 - PMCID: PMC3774301 - DOI: 10.1016/j.celrep.2013.04.021

Lan YY, Londoño D, Bouley R, Rooney MS, Hacohen N

Dnase2a Deficiency Uncovers Lysosomal Clearance of Damaged Nuclear DNA via Autophagy. Cell Rep. 2014;9(1):180-92 - PMID: 25284779 - PMCID: PMC4555847 - DOI: 10.1016/j.celrep.2014.08.074

Levy O, Mortensen LJ, Boquet G, Tong Z, Perrault C, Benhamou B, Zhang J, Stratton T, Han E, Safaee H, Musabeyezu J, Yang Z, Multon MC, Rothblatt J, Deleuze JF, Lin CP, Karp JM

A Small-Molecule Screen for Enhanced Homing of Systemically Infused Cells. Cell Rep. 2015;10(8):1261-1268 - PMID: 25732817 - PMCID: PMC4361231 - DOI: 10.1016/j.celrep.2015.01.057

Pucci F, Rickelt S, Newton AP, Garris C, Nunes E, Evavold C, Pfirschke C, Engblom C, Mino-Kenudson M, Hynes RO, Weissleder R, Pittet MJ

PF4 Promotes Platelet Production and Lung Cancer Growth. Cell Rep. 2016;17(7):1764-1772 - PMID: 27829148 - PMCID: PMC5108525 - DOI: 10.1016/j.celrep.2016.10.031

Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS

A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas. Cell Rep. 2017;21(3):784-797 - PMID: 29045844 - PMCID: PMC5687286 - DOI: 10.1016/j.celrep.2017.09.066

Zaborowski MP, Lee K, Na YJ, Sammarco A, Zhang X, Iwanicki M, Cheah PS, Lin HY, Zinter M, Chou CY, Fulci G, Tannous BA, Lai CP, Birrer MJ, Weissleder R, Lee H, Breakefield XO

Methods for Systematic Identification of Membrane Proteins for Specific Capture of Cancer-Derived Extracellular Vesicles. Cell Rep. 2019;27(1):255-268.e6 - PMID: 30943406 - PMCID: PMC6528836 - DOI: 10.1016/j.celrep.2019.03.003

Shikatani EA, Besla R, Ensan S, Upadhye A, Khyzha N, Li A, Emoto T, Chiu F, Degousee N, Moreau JM, Perry HM, Thayaparan D, Cheng HS, Pacheco S, Smyth D, Noyan H, Zavitz CCJ, Bauer CMT, Hilgendorf I, Libby P, Swirski FK, Gommerman JL, Fish JE, Stampfli MR, Cybulsky MI, Rubin BB, Paige CJ, Bender TP, McNamara CA, Husain M, Robbins CS

c-Myb Exacerbates Atherosclerosis through Regulation of Protective IgM-Producing Antibody-Secreting Cells. Cell Rep. 2019;27(8):2304-2312.e6 - PMID: 31116977 - DOI: 10.1016/j.celrep.2019.04.090

Gyuris A, Navarrete-Perea J, Jo A, Cristea S, Zhou S, Fraser K, Wei Z, Krichevsky AM, Weissleder R, Lee H, Gygi SP, Charest A

Physical and Molecular Landscapes of Mouse Glioma Extracellular Vesicles Define Heterogeneity. Cell Rep. 2019;27(13):3972-3987.e6 - PMID: 31242427 - PMCID: PMC6604862 - DOI: 10.1016/j.celrep.2019.05.089

Pfirschke C, Engblom C, Gungabeesoon J, Lin Y, Rickelt S, Zilionis R, Messemaker M, Siwicki M, Gerhard GM, Kohl A, Meylan E, Weissleder R, Klein AM, Pittet MJ

Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils. Cell Rep. 2020;32(12):108164 - PMID: 32966785 - PMCID: PMC7508173 - DOI: 10.1016/j.celrep.2020.108164

Kim IS, Wu J, Rahme GJ, Battaglia S, Dixit A, Gaskell E, Chen H, Pinello L, Bernstein BE

Parallel Single-Cell RNA-Seq and Genetic Recording Reveals Lineage Decisions in Developing Embryoid Bodies. Cell Rep. 2020;33(1):108222 - PMID: 33027665 - PMCID: PMC7646252 - DOI: 10.1016/j.celrep.2020.108222

Barrett TJ, Corr EM, van Solingen C, Schlamp F, Brown EJ, Koelwyn GJ, Lee AH, Shanley LC, Spruill TM, Bozal F, de Jong A, Newman AAC, Drenkova K, Silvestro M, Ramkhelawon B, Reynolds HR, Hochman JS, Nahrendorf M, Swirski FK, Fisher EA, Berger JS, Moore KJ

Chronic stress primes innate immune responses in mice and humans. Cell Rep. 2021;36(10):109595 - PMID: 34496250 - PMCID: PMC8493594 - DOI: 10.1016/j.celrep.2021.109595

Guo JA, Gong D, Evans K, Takahashi K, Jambhale AD, Shiau C, Yu P, Wang S, Wu WW, Chugh S, Kapner KS, Dilly J, Zhao D, Chen P, Smith EL, Mancias JD, Vazquez F, Singh H, Hwang WL, Aguirre AJ

Integrative genomic identification of therapeutic targets for pancreatic cancer. Cell Rep. 2025;44(9):116191 - PMID: 40848256 - DOI: 10.1016/j.celrep.2025.116191

Park J*, Im H*, Hong S, Castro CM, Weissleder R, Hakho Lee H

Analyses of Intravesicular Exosomal Proteins Using a Nano-Plasmonic System ACS Photonics. 2017;5(2):487-494 - PMID: 29805987 - PMCID: PMC5966285 - DOI: 10.1021/acsphotonics.7b00992

Giacomini KM, Yee SW, Koleske ML, Zou L, Matsson P, Chen E, Kroetz DL, Miller MA, Gozalpour E, Chu X

New and emerging research on solute carrier (SLC) and ABC transporters in drug discovery and development: Outlook from the International Transporter Consortium. Clin Pharmacol Ther. 2022;112(3):540-561 - PMID: 35488474 - PMCID: PMC9398938 - DOI: 10.1002/cpt.2627

Lee H, Liu Y, Ham D, Westervelt RM

Integrated cell manipulation system--CMOS/microfluidic hybrid. Lab Chip. 2007;7(3):331-7 - PMID: 17330164 - DOI: 10.1039/b700373k

Issadore D, Shao H, Chung J, Newton A, Pittet M, Weissleder R, Lee H

Self-assembled magnetic filter for highly efficient immunomagnetic separation. Lab Chip. 2010;11(1):147-51 - PMID: 20949198 - PMCID: PMC3005961 - DOI: 10.1039/c0lc00149j

Issadore D, Min C, Liong M, Chung J, Weissleder R, Lee H

Miniature magnetic resonance system for point-of-care diagnostics. Lab Chip. 2011;11(13):2282-7 - PMID: 21547317 - PMCID: PMC3115660 - DOI: 10.1039/c1lc20177h

Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY

On-chip bioorthogonal chemistry enables immobilization of in situ modified nanoparticles and small molecules for label-free monitoring of protein binding and reaction kinetics. Lab Chip. 2012;12(17):3103-10 - PMID: 22760641 - PMCID: PMC3411869 - DOI: 10.1039/c2lc40337d

Castro CM, Ghazani AA, Chung J, Shao H, Issadore D, Yoon TJ, Weissleder R, Lee H

Miniaturized nuclear magnetic resonance platform for detection and profiling of circulating tumor cells. Lab Chip. 2013;14(1):14-23 - PMID: 23835814 - PMCID: PMC3844052 - DOI: 10.1039/c3lc50621e

Issadore D, Park YI, Shao H, Min C, Lee K, Liong M, Weissleder R*, Lee H*

Magnetic sensing technology for molecular analyses. Lab Chip. 2014;14(14):2385-97 - PMID: 24887807 - PMCID: PMC4098149 - DOI: 10.1039/c4lc00314d

Im H, Park YI, Pathania D, Castro CM, Weissleder R, Lee H

Digital diffraction detection of protein markers for avian influenza. Lab Chip. 2016;16(8):1340-5 - PMID: 26980325 - PMCID: PMC4829473 - DOI: 10.1039/c5lc01558h

Ng EX, Miller MA, Jing T, Lauffenburger DA, Chen CH

Low-volume multiplexed proteolytic activity assay and inhibitor analysis through a pico-injector array. Lab Chip. 2015;15(4):1153-9 - PMID: 25553996 - DOI: 10.1039/c4lc01162g

Lindquist NC, Lesuffleur A, Im H, Oh SH

Sub-micron resolution surface plasmon resonance imaging enabled by nanohole arrays with surrounding Bragg mirrors for enhanced sensitivity and isolation. Lab Chip. 2008;9(3):382-7 - PMID: 19156286 - DOI: 10.1039/b816735d

Im H, Lee K, Weissleder R, Lee H, Castro CM

Novel nanosensing technologies for exosome detection and profiling. Lab Chip. 2017;17(17):2892-2898 - PMID: 28745363 - PMCID: PMC5572557 - DOI: 10.1039/c7lc00247e

Min C, Park J, Mun JK, Lim Y, Min J, Lim JW, Kang DM, Ahn HK, Shin TH, Cheon J, Lee HS, Weissleder R, Castro CM, Lee H

Integrated microHall magnetometer to measure the magnetic properties of nanoparticles. Lab Chip. 2017;17(23):4000-4007 - PMID: 29067383 - PMCID: PMC5698130 - DOI: 10.1039/c7lc00934h

Szafraniec HM, Valdez JM, Iffrig E, Lam WA, Higgins JM, Pearce P, Wood DK

Feature tracking microfluidic analysis reveals differential roles of viscosity and friction in sickle cell blood. Lab Chip. 2022;22(8):1565-1575 - PMID: 35315465 - PMCID: PMC9004467 - DOI: 10.1039/d1lc01133b

Lucas K, Oh J, Hoelzl J, Weissleder R

Cellular point-of-care diagnostics using an inexpensive layer-stack microfluidic device. Lab Chip. 2022;22:2145 - 2154 - PMID: 35514273 - PMCID: PMC9214713 - DOI: 10.1039/d2lc00162d

Iyer V, Yang Z, Ko J, Weissleder R, Issadore D

Advancing microfluidic diagnostic chips into clinical use: a review of current challenges and opportunities. Lab Chip. 2022;22(17):3110-3121 - PMID: 35674283 - PMCID: PMC9798730 - DOI: 10.1039/d2lc00024e

Gonçalves I, den Ruijter H, Nahrendorf M, Pasterkamp G

Detecting the vulnerable plaque in patients. J Intern Med. 2015;278(5):520-30 - PMID: 26306911 - DOI: 10.1111/joim.12414

Nahrendorf M

Myeloid cells in cardiovascular organs. J Intern Med. 2018;285(5):491-502 - PMID: 30585362 - PMCID: PMC6497541 - DOI: 10.1111/joim.12844

Shaw SY, Cheng S, Cupples LA, Larson MG, McCabe EL, Ngwa JS, Wang YA, Martin RP, Klein RJ, Hashmi B, Ajijola OA, Lau E, O'Donnell CJ, Vasan RS, Cohen KS, Wang TJ

Genetic and Clinical Correlates of Early Outgrowth Colony Forming Units. Circ Cardiovasc Genet. 2011;4(3):296-304 - PMID: 21493818 - PMCID: PMC3339257 - DOI: 10.1161/CIRCGENETICS.110.958470

Hall JL, Ryan JJ, Bray BE, Brown C, Lanfear D, Newby LK, Relling MV, Risch NJ, Roden DM, Shaw SY, Tcheng JE, Tenenbaum J, Wang TN, Weintraub WS

Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association. Circ Cardiovasc Genet. 2016;9(2):193-202 - PMID: 26976545 - PMCID: PMC5646218 - DOI: 10.1161/HCG.0000000000000029

McCarthy JR, Bhaumik J, Karver MR, Sibel Erdem S, Weissleder R

Targeted nanoagents for the detection of cancers. Mol Oncol. 2010;4(6):511-28 - PMID: 20851695 - PMCID: PMC2981649 - DOI: 10.1016/j.molonc.2010.08.003

Tsourkas A, Newton G, Perez JM, Basilion J, Weissleder R.

Detection of Peroxidase-Mediated Dityrosine Formation with Enhanced Yellow Fluorescent Protein Anal Chem. 2005;77:2862-2867 - PMID: 15859603 - DOI: 10.1021/ac0480747

Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L

Multiparameter Magnetic Relaxation Switch Assays. Anal Chem. 2007;(79) 23:8863-9 - PMID: 17983206 - DOI: 10.1021/ac701976p

Koh I, Hong R, Weissleder R, Josephson L

Nanoparticle-Target Interactions Parallel Antibody-Protein Interactions. Anal Chem. 2009;81(9):3618-22 - PMID: 19323458 - PMCID: PMC2690647 - DOI: 10.1021/ac802717c

Niers JM, Chen JW, Weissleder R, Tannous BA

Enhanced in Vivo Imaging of Metabolically Biotinylated Cell Surface Reporters. Anal Chem. 2011;83(3):994-9 - PMID: 21214190 - PMCID: PMC3059349 - DOI: 10.1021/ac102758m

Roussakis E, Spencer JA, Lin CP, Vinogradov SA

Two-Photon Antenna-Core Oxygen Probe with Enhanced Performance. Anal Chem. 2014;86(12):5937-45 - PMID: 24848643 - PMCID: PMC4066907 - DOI: 10.1021/ac501028m

Wittenberg NJ, Im H, Xu X, Wootla B, Watzlawik J, Warrington AE, Rodriguez M, Oh SH

High-affinity binding of remyelinating natural autoantibodies to myelin-mimicking lipid bilayers revealed by nanohole surface plasmon resonance. Anal Chem. 2012;84(14):6031-9 - PMID: 22762372 - PMCID: PMC3417152 - DOI: 10.1021/ac300819a

Im H, Sutherland JN, Maynard JA, Oh SH

Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics. Anal Chem. 2012;84(4):1941-7 - PMID: 22235895 - PMCID: PMC3307221 - DOI: 10.1021/ac300070t

Im H, Lesuffleur A, Lindquist NC, Oh SH

Plasmonic nanoholes in a multichannel microarray format for parallel kinetic assays and differential sensing. Anal Chem. 2009;81(8):2854-9 - PMID: 19284776 - PMCID: PMC2720634 - DOI: 10.1021/ac802276x

Ng EX, Sun G, Wei SC, Miller MA, Dasgupta R, Lam PYP, Chen CH

Ultrafast Single-Cell Level Enzymatic Tumor Profiling. Anal Chem. 2018;91(2):1277-1285 - PMID: 30362713 - DOI: 10.1021/acs.analchem.8b02576

Stopka SA, Bodineau C, Baquer G, Lin JR, Hossain MA, Martinez CJ, Regan MS, Ruiz D, Fletcher SM, Pourquié O, Lutsenko S, Payne CN, Agar JN, Mazitschek R, McDannold NJ, Sorger PK, Santagata S, Agar NYR

Spatial Profiling of Elements through Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging. Anal Chem. 2025;97(45):25334-25345 - PMID: 41201007 - DOI: 10.1021/acs.analchem.5c05632

Figueiredo JL, Nahrendorf M, Sosnovik DE, Weissleder R

MRI of a Novel Murine Working Heart Transplant Model Circ Heart Fail. 2009;2:272-274 - PMID: 19718275 - PMCID: PMC2733535 - DOI: 10.1161/CIRCHEARTFAILURE.109.852707

He S, Chousterman BG, Fenn A, Anzai A, Nairz M, Brandt M, Hilgendorf I, Sun Y, Ye YX, Iwamoto Y, Tricot B, Weissleder R, Macphee C, Libby P, Nahrendorf M, Swirski FK

Lp-PLA2 Antagonizes Left Ventricular Healing After Myocardial Infarction by Impairing the Appearance of Reparative Macrophages. Circ Heart Fail. 2015;8(5):980-7 - PMID: 26232205 - PMCID: PMC4568849 - DOI: 10.1161/CIRCHEARTFAILURE.115.002334

Valero-Muñoz M, Li S, Wilson RM, Hulsmans M, Aprahamian T, Fuster JJ, Nahrendorf M, Scherer PE, Sam F

Heart Failure With Preserved Ejection Fraction Induces Beiging in Adipose Tissue. Circ Heart Fail. 2016;9(1):e002724 - PMID: 26721917 - PMCID: PMC4698901 - DOI: 10.1161/CIRCHEARTFAILURE.115.002724

Naxerova K

Defining the role of lymph node metastasis in systemic breast cancer evolution. EBioMedicine. 2020;57:102852 - PMID: 32574957 - PMCID: PMC7322247 - DOI: 10.1016/j.ebiom.2020.102852

Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP

Association Between Reduced Plasma 25-hydroxy Vitamin D and Increased Risk of Cancer in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2013;12(5):821-7 - PMID: 24161349 - PMCID: PMC3995841 - DOI: 10.1016/j.cgh.2013.10.011

Ananthakrishnan AN, Cheng SC, Cai T, Cagan A, Gainer VS, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP

Serum Inflammatory Markers and Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2014;12(8):1342-1348.e1 - PMID: 24407106 - PMCID: PMC4085150 - DOI: 10.1016/j.cgh.2013.12.030

Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Scoville E, Konijeti GG, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP

Thromboprophylaxis is associated with reduced post-hospitalization venous thromboembolic events in patients with inflammatory bowel diseases. Clin Gastroenterol Hepatol. 2014;12(11):1905-1910 - PMID: 24632349 - PMCID: PMC4162859 - DOI: 10.1016/j.cgh.2014.02.034

Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP

Colonoscopy is Associated with a Reduced Risk for Colon Cancer and Mortality in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2014;13(2):322-329.e1 - PMID: 25041865 - PMCID: PMC4297589 - DOI: 10.1016/j.cgh.2014.07.018

Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I

Statin use is Associated With Reduced Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases. Clin Gastroenterol Hepatol. 2016;14(7):973-9 - PMID: 26905907 - PMCID: PMC4912917 - DOI: 10.1016/j.cgh.2016.02.017

Sanford NN, Mahal BA, Royce TJ, Pike LRG, Hwang WL

Sex Disparity and Copy Number Alterations in Esophageal Squamous Cell Carcinoma. Clin Gastroenterol Hepatol. 2018;17(6):1207-1209 - PMID: 30120994 - DOI: 10.1016/j.cgh.2018.08.026

Jaffer FA, Tung CH, Gerszten RE, Weissleder R

In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe Arterioscler Thromb Vasc Biol. 2002;22:1929-35 - PMID: 12426227 - DOI: 10.1161/01.atv.0000033089.56970.2d

Simoncini T, Rabkin E, Liao J

Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells. Arterioscler Thromb Vasc Biol. 2003;23:198-203 - PMID: 12588759 - DOI: 10.1161/01.atv.0000053846.71621.93

Jaffer FA, Libby P, Weissleder R

Optical and Multimodality Molecular Imaging. Insights Into Atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29(7):1017-24 - PMID: 19359659 - PMCID: PMC2733228 - DOI: 10.1161/ATVBAHA.108.165530

Swirski FK, Weissleder R, Pittet MJ

Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2009;29(10):1424-32 - PMID: 19372462 - PMCID: PMC2746262 - DOI: 10.1161/ATVBAHA.108.180521

Nahrendorf M, Waterman P, Thurber G, Groves K, Rajopadhye M, Panizzi P, Marinelli B, Aikawa E, Pittet MJ, Swirski FK, Weissleder R

Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors. Arterioscler Thromb Vasc Biol. 2009;29(10):1444-51 - PMID: 19608968 - PMCID: PMC2746251 - DOI: 10.1161/ATVBAHA.109.193086

Deguchi JO, Yamazaki H, Aikawa E, Aikawa M

Chronic Hypoxia Activates the Akt and {beta}-Catenin Pathways in Human Macrophages. Arterioscler Thromb Vasc Biol. 2009;29(10):1664-70 - PMID: 19644051 - DOI: 10.1161/ATVBAHA.109.194043

Chang K, Francis SA, Aikawa E, Figueiredo JL, Kohler RH, McCarthy JR, Weissleder R, Plutzky J, Jaffer FA

Pioglitazone Suppresses Inflammation In Vivo in Murine Carotid Atherosclerosis. Novel Detection by Dual-Target Fluorescence Molecular Imaging. Arterioscler Thromb Vasc Biol. 2010;30(10):1933-9 - PMID: 20689078 - PMCID: PMC3030475 - DOI: 10.1161/ATVBAHA.110.206342

Nahrendorf M, Keliher E, Marinelli B, Leuschner F, Robins CS, Gerszten RE, Pittet MJ, Swirski FK, Weissleder R

Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography-Computed Tomography. Arterioscler Thromb Vasc Biol. 2011;31(4):750-7 - PMID: 21252070 - PMCID: PMC3060293 - DOI: 10.1161/ATVBAHA.110.221499

Swirski FK

The spatial and developmental relationships in the macrophage family. Arterioscler Thromb Vasc Biol. 2011;31(7):1517-22 - PMID: 21677294 - PMCID: PMC3117206 - DOI: 10.1161/ATVBAHA.110.221150

Ripplinger CM, Kessinger CW, Li C, Kim JW, McCarthy JR, Weissleder R, Henke PK, Lin CP, Jaffer FA

Inflammation Modulates Murine Venous Thrombosis Resolution In Vivo: Assessment by Multimodal Fluorescence Molecular Imaging. Arterioscler Thromb Vasc Biol. 2012;32(11):2616-24 - PMID: 22995524 - PMCID: PMC3516622 - DOI: 10.1161/ATVBAHA.112.251983

Hilgendorf I, Swirski FK, Robbins CS

Monocyte Fate in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2014;35(2):272-9 - PMID: 25538208 - DOI: 10.1161/ATVBAHA.114.303565

Dutta P, Nahrendorf M

Monocytes in Myocardial Infarction. Arterioscler Thromb Vasc Biol. 2015;35(5):1066-70 - PMID: 25792449 - PMCID: PMC4409536 - DOI: 10.1161/ATVBAHA.114.304652

Calcagno C, Mulder WJ, Nahrendorf M, Fayad ZA

Systems Biology and Noninvasive Imaging of Atherosclerosis. Arterioscler Thromb Vasc Biol. 2016;36(2):e1-8 - PMID: 26819466 - PMCID: PMC4861402 - DOI: 10.1161/ATVBAHA.115.306350

Babaev VR, Ding L, Zhang Y, May JM, Lin CP, Fazio S, Linton MF

Macrophage IκB Kinase α Deficiency Suppresses Akt Phosphorylation, Reduces Cell Survival, and Decreases Early Atherosclerosis. Arterioscler Thromb Vasc Biol. 2016;36(4):598-607 - PMID: 26848161 - PMCID: PMC4808396 - DOI: 10.1161/ATVBAHA.115.306931

Dutta P, Hoyer FF, Sun Y, Iwamoto Y, Tricot B, Weissleder R, Magnani JL, Swirski FK, Nahrendorf M

E-Selectin Inhibition Mitigates Splenic HSC Activation and Myelopoiesis in Hypercholesterolemic Mice With Myocardial Infarction. Arterioscler Thromb Vasc Biol. 2016;36(9):1802-8 - PMID: 27470513 - PMCID: PMC5001901 - DOI: 10.1161/ATVBAHA.116.307519

Vergallo R, Uemura S, Soeda T, Minami Y, Cho JM, Ong DS, Aguirre AD, Gao L, Biasucci LM, Crea F, Yu B, Lee H, Kim CJ, Jang IK

Prevalence and Predictors of Multiple Coronary Plaque Ruptures: In Vivo 3-Vessel Optical Coherence Tomography Imaging Study. Arterioscler Thromb Vasc Biol. 2016;36(11):2229-2238 - PMID: 27634834 - DOI: 10.1161/ATVBAHA.116.307891

Libby P, King K

Biomarkers: A Challenging Conundrum in Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2015;35(12):2491-5 - PMID: 26543097 - DOI: 10.1161/ATVBAHA.115.305233

Fenn AM, Swirski FK

Monocytosis, Hypercholesterolemia, and the Kinase That Binds Them. Arterioscler Thromb Vasc Biol. 2017;37(2):173-175 - PMID: 28122772 - DOI: 10.1161/ATVBAHA.116.308768

Swirski FK

Rings of Fire. Arterioscler Thromb Vasc Biol. 2018;38(8):1671-1672 - PMID: 30354199 - DOI: 10.1161/ATVBAHA.118.311389

Mindur JE, Swirski FK

Growth Factors as Immunotherapeutic Targets in Cardiovascular Disease. Arterioscler Thromb Vasc Biol. 2019;39(7):1275-1287 - PMID: 31092009 - PMCID: PMC6613384 - DOI: 10.1161/ATVBAHA.119.311994

Nahrendorf M

Tuning Into Immune Cell Responses of Chronic Stress With Intravital Microscopy. Arterioscler Thromb Vasc Biol. 2024;44(12):2507-2508 - PMID: 39445423 - DOI: 10.1161/ATVBAHA.124.321865

Querol M, Chen JW, Weissleder R, Bogdanov A Jr.

DTPA-bisamide-Based MR Sensor Agents for Peroxidase Imaging Org Lett. 2005;7(9):1719-22 - PMID: 15844889 - DOI: 10.1021/ol050208v

Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA

A Highly Selective Fluorescent Probe for Thiol Bioimaging. Org Lett. 2007;10 :37-40 - PMID: 18062694 - DOI: 10.1021/ol702539v

McCarthy JR, Jenkins HA, Bruckner C

Free base meso-tetraaryl-morpholinochlorins and porpholactone from meso-tetraaryl-2,3-dihydroxy-chlorin. Org Lett. 2003;5(1):19-22

Urgaonkar S, Cortese JF, Barker RH, Cromwell M, Serrano AE, Wirth DF, Clardy J, Mazitschek R

A Concise Silylamine Approach to 2-Amino-3-hydroxy-indoles with Potent in vivo Antimalaria Activity. Org Lett. 2010;12(18):3998-4001 - PMID: 20718474 - PMCID: PMC7479540 - DOI: 10.1021/ol101566h

Castro CM, Im H, Le C, Lee H, Weissleder R, Birrer MJ

Exploring alternative ovarian cancer biomarkers using innovative nanotechnology strategies. Cancer Metastasis Rev. 2015;34(1):75-82 - PMID: 25543192 - PMCID: PMC5474936 - DOI: 10.1007/s10555-014-9546-9

Tong T, Yang Z, Chen JW, Zhu J, Yao Z

Dynamic 1H-MRS assessment of brain tumors: A novel approach for differential diagnosis of glioma. Oncotarget. 2015;6(31):32257-32265 - PMID: 26337080 - PMCID: PMC4741675 - DOI: 10.18632/oncotarget.4899

Nahrendorf M, Dutta P

Targeting splenic hematopoietic stem cells in cardiovascular disease. Oncotarget. 2015;6(24):19918-9 - PMID: 26343366 - PMCID: PMC4652955 - DOI: 10.18632/oncotarget.4918

Cotter K, Liberman R, Sun-Wada G, Wada Y, Sgroi D, Naber S, Brown D, Breton S, Forgac M

The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer. Oncotarget. 2016;7(29):46142-46157 - PMID: 27323815 - PMCID: PMC5216787 - DOI: 10.18632/oncotarget.10063

Huang P, Almeciga-Pinto I, Jarpe M, van Duzer JH, Mazitschek R, Yang M, Jones SS, Quayle SN

Selective HDAC inhibition by ACY-241 enhances the activity of paclitaxel in solid tumor models. Oncotarget. 2017;8(2):2694-2707 - PMID: 27926524 - PMCID: PMC5356834 - DOI: 10.18632/oncotarget.13738

Hideshima T, Mazitschek R, Qi J, Mimura N, Tseng JC, Kung AL, Bradner JE, Anderson KC

HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer. Oncotarget. 2017;8(46):80109-80123 - PMID: 29113288 - PMCID: PMC5655183 - DOI: 10.18632/oncotarget.19019

Hideshima T, Mazitschek R, Qi J, Mimura N, Tseng JC, Kung AL, Bradner JE, Anderson KC

HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer. Oncotarget. 2017;8(46):80109-80123 - PMID: 29113288 - PMCID: PMC5655183 - DOI: 10.18632/oncotarget.19019

Seldon CS, Meiyappan K, Hoffman H, Guo JA, Goel N, Hwang WL, Nguyen PL, Mahal BA, Alshalalfa M

Genomic alterations predictive of poor clinical outcomes in pan-cancer. Oncotarget. 2022;13:1069-1077 - PMID: 36187555 - PMCID: PMC9518688 - DOI: 10.18632/oncotarget.28276

Hwang I, Oh H, Santo E, Kim DY, Chen JW, Bronson RT, Locasale JW, Na Y, Lee J, Reed S, Toth M, Yu WH, Muller FL, Paik J

FOXO protects against age-progressive axonal degeneration. Aging Cell. 2017;17(1):ePub - PMID: 29178390 - PMCID: PMC5771393 - DOI: 10.1111/acel.12701

Lan YY, Heather JM, Eisenhaure T, Garris CS, Lieb D, Raychowdhury R, Hacohen N

Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation. Aging Cell. 2019;18(2):e12901 - PMID: 30706626 - PMCID: PMC6413746 - DOI: 10.1111/acel.12901

Hilderbrand S, Weissleder R.

Optimized pH-responsive cyanine fluorochromes for detection of acidic environments Chem Commun. 2007;(26):2747-9 - PMID: 17594041 - DOI: 10.1039/b703764c

Kim YM, Hilderbrand S, Weissleder R, Tung CH

Sugar sensing based on induced pH changes Chem Commun. 2007;(22):2299-2301 - PMID: 17534523 - DOI: 10.1039/b700741h

McCarthy JR, Hyland MA, Bruckner C

Indaphyrin, a meso-tetraphenylsecochlorin-derived chromophore incorporating o-phenyl-to-β-linkages Chem Commun. 2003;:1738-9

Garanger E, Aikawa E, Reynolds F, Weissleder R, Josephson L

Simplified syntheses of complex multifunctional nanomaterials. Chem Commun. 2008;39:4792-4 - PMID: 18830495 - PMCID: PMC2692914 - DOI: 10.1039/b809537j

Hilderbrand SA, Shao F, Salthouse C, Mahmood U, Weissleder R

Upconverting luminescent nanomaterials: application to in vivo bioimaging. Chem Commun. 2009;28:4188-90 - PMID: 19585016 - PMCID: PMC2748243 - DOI: 10.1039/b905927j

Garanger E, Hilderbrand SA, Blois JT, Sosnovik DE, Weissleder R, Josephson L

A DNA-binding Gd chelate for the detection of cell death by MRI. Chem Commun. 2009;(29):4444-6 - PMID: 19597620 - PMCID: PMC2754278 - DOI: 10.1039/b907375b

Agasti SS, Laughney AM, Kohler RH, Weissleder R

A photoactivatable drug–caged fluorophore conjugate allows direct quantification of intracellular drug transport Chem Commun. 2013;49(94):11050-2 - PMID: 24135896 - PMCID: PMC3856557 - DOI: 10.1039/c3cc46089d

Kim E, Yang KS, Giedt RJ, Weissleder R

Red Si-rhodamine drug conjugates enable imaging in GFP cells. Chem Commun. 2014;50(34):4504-7 - PMID: 24663433 - PMCID: PMC4028821 - DOI: 10.1039/c4cc00144c

Meimetis LG, Giedt R, Mikyla H, Carlson J, Kohler R, Pirovich DB, Weissleder R

Fluorescent vinblastine probes for live cell imaging Chem Commun. 2016;52(64):9953-6 - PMID: 27439765 - PMCID: PMC4970878 - DOI: 10.1039/c6cc04129a

Hong S, Park KS, Weissleder R, Castro CM, Lee H

Facile silicification of plastic surface for bioassays. Chem Commun. 2017;53(13):2134-2137 - PMID: 28134385 - PMCID: PMC5327824 - DOI: 10.1039/c6cc09359k

Miller MA, Kim E, Cuccarese MF, Plotkin AL, Prytyskach M, Kohler RH, Pittet MJ, Weissleder R

Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease Chem Commun. 2017;54(1):42-45 - PMID: 29185561 - PMCID: PMC5736449 - DOI: 10.1039/c7cc07581b

Inoue Y, Yu YM, Kurihara T, Vasilyev A, Ibrahim A, Oklu R, Zhao G, Nair AV, Brown D, Fischman AJ, Tompkins RG, Irimia D

Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2. Crit Care Med. 2016;44(5):e241-52 - PMID: 26509319 - PMCID: PMC4833510 - DOI: 10.1097/CCM.0000000000001397

Li K, Rodosthenous RS, Kashanchi F, Gingeras T, Gould SJ, Kuo LS, Kurre P, Lee H, Leonard JN, Liu H, Lombo TB, Momma S, Nolan JP, Ochocinska MJ, Pegtel DM, Sadovsky Y, Sánchez-Madrid F, Valdes KM, Vickers KC, Weaver AM, Witwer KW, Zeng Y, Das S, Raffai RL, Howcroft TK

Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop. JCI Insight. 2018;3(7):ePub - PMID: 29618663 - PMCID: PMC5928855 - DOI: 10.1172/jci.insight.98942

Oh J, Magnuson A, Benoist C, Pittet MJ, Weissleder R

Age-related tumor growth in mice is related to integrin α 4 in CD8+ T cells JCI Insight. 2018;3(21):ePub - PMID: 30385729 - PMCID: PMC6238736 - DOI: 10.1172/jci.insight.122961

Tsai HC, Huang Y, Garris CS, Moreno MA, Griffin CW, Han MH

Effects of sphingosine-1-phosphate receptor 1 phosphorylation in response to FTY720 during neuroinflammation. JCI Insight. 2016;1(9):e86462 - PMID: 27699272 - PMCID: PMC5033897 - DOI: 10.1172/jci.insight.86462

Bapat A, Li G, Xiao L, Yeri A, Hulsmans M, Grune J, Yamazoe M, Schloss MJ, Iwamoto Y, Tedeschi JG, Yang X, Nahrendorf M, Rosenzweig A, Ellinor PT, Das S, Milan D

Genetic inhibition of serum glucocorticoid kinase 1 prevents obesity-related atrial fibrillation. JCI Insight. 2022;7(19):ePub - PMID: 35998035 - PMCID: PMC9675459 - DOI: 10.1172/jci.insight.160885

Chen SY, Kung HC, Espinoza B, Washington I, Chen K, Wang J, Zlomke H, Loycano MA, Wang R, Pickup M, Burns Iii WR, Fu J, Hwang WL, Zheng L

Targeting heterogeneous tumor microenvironments in pancreatic cancer mouse models of metastasis by TGFβ depletion. JCI Insight. 2024;9(21):ePub - PMID: 39298276 - PMCID: PMC11610749 - DOI: 10.1172/jci.insight.182766

McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW

Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy. Neuroimage. 2008;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022

Hyde D, de Kleine R, MacLaurin S, Miller E, Brooks D, Krucker T, Ntziachristos V

Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model. Neuroimage. 2009;44(4):1304-11 - PMID: 19041402 - DOI: 10.1016/j.neuroimage.2008.10.038

Shiau C, Su J, Guo JA, Hong TS, Wo JY, Jagadeesh KA, Hwang WL

Treatment-associated remodeling of the pancreatic cancer endothelium at single-cell resolution. Front Oncol. 2022;12:929950 - PMID: 36185212 - PMCID: PMC9524152 - DOI: 10.3389/fonc.2022.929950

Yuan H, Luo J, Weissleder R, Cantley L, Josephson L

Wortmannin-C20 Conjugates Generate Wortmannin. J Med Chem. 2006;49(2):740-747 - PMID: 16420059 - DOI: 10.1021/jm050699p

Galande A, Hilderbrand S, Weissleder R, Tung CH.

Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core J Med Chem. 2006;49(15):4715-20 - PMID: 16854078 - DOI: 10.1021/jm051001a

Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L.

Multivalent effects of RGD peptides obtained by nanoparticle display J Med Chem. 2006;49(20):6087-6093

Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L

Slow Self-Activation Enhances The Potency of Viridin Prodrugs. J Med Chem. 2008;51(15):4699-707 - PMID: 18630894 - PMCID: PMC2663427 - DOI: 10.1021/jm800374f

Estiu G, Greenberg E, Harrison C, Kwiatkowski N, Mazitschek R, Bradner J, Wiest O

Structural origin of selectivity in class II-selective histone deacetylase inhibitors. J Med Chem. 2008;51:2898-906 - PMID: 18412327 - DOI: 10.1021/jm7015254

Patel V, Mazitschek R, Coleman B, Nguyen C, Urgaonkar S, Cortese J, Barker RH, Greenberg E, Tang W, Bradner JE, Schreiber SL, Duraisingh MT, Wirth DF, Clardy J

Identification and Characterization of Small Molecule Inhibitors of a Class I Histone Deacetylase from Plasmodium falciparum. J Med Chem. 2009;52(8):2185-7 - PMID: 19317450 - PMCID: PMC2669731 - DOI: 10.1021/jm801654y

Hendricks JA, Keliher EJ, Marinelli B, Reiner T, Weissleder R, Mazitschek R

In Vivo PET-imaging of Histone Deacetylases by 18F-Suberoylanilide Hydroxamic Acid (18F-SAHA). J Med Chem. 2011;54(15):5576-82 - PMID: 21721525 - PMCID: PMC3150598 - DOI: 10.1021/jm200620f

Kissau L, Stahl P, Mazitschek R, Giannis A, Waldmann H

Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold. J Med Chem. 2003;46(14):2917-31 - PMID: 12825933 - DOI: 10.1021/jm0307943

Wang C, Cheng D, Jalali Motlagh N, Kuellenberg EG, Wojtkiewicz GR, Schmidt SP, Stocker R, Chen JW

Highly Efficient Activatable MRI Probe to Sense Myeloperoxidase Activity. J Med Chem. 2021;64(9):5874-5885 - PMID: 33945286 - PMCID: PMC8564765 - DOI: 10.1021/acs.jmedchem.1c00038

Lewin M, Bredow S, Sergeyev N, Marecos E, Bogdanov A Jr, Weissleder R

In vivo assessment of vascular endothelial growth factor-induced angiogenesis Int J Cancer. 1999;83:798-802 - PMID: 10597197 - DOI: 10.1002/(sici)1097-0215(19991210)83:6<798::aid-ijc16>3.0.co;2-w

Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U.

A novel mouse model for segmental orthotopic colon cancer Int J Cancer. 2005;117(3):335-9 - PMID: 15900588 - DOI: 10.1002/ijc.21185

Figueiredo JL, Alencar H, Weissleder R, Mahmood U

Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006;118(11):2672-7 - PMID: 16380983 - DOI: 10.1002/ijc.21713

Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U

Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007;(121) 11:2492-2500 - PMID: 17683072 - DOI: 10.1002/ijc.22995

Kirkin V, Thiele W, Baumann P, Mazitschek R, Rohde K, Fellbrich G, Weich H, Waltenberger J, Giannis A, Sleeman JP

MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo. Int J Cancer. 2004;112(6):986-93 - PMID: 15386354 - DOI: 10.1002/ijc.20509

Brotherton JM, Jit M, Gravitt PE, Brisson M, Kreimer AR, Pai SI, Fakhry C, Monsonego J, Franceschi S

Eurogin Roadmap 2015: How has HPV knowledge changed our practice: Vaccines. Int J Cancer. 2016;139(3):510-7 - PMID: 26916230 - PMCID: PMC7388730 - DOI: 10.1002/ijc.30063

Lacy-Hulbert A*, Ueno T*, Ito T, Jurewicz M, Izawa A, Smith RN, Chase CM, Tanaka K, Fiorina P, Russell PS, Auchincloss H, Sayegh MH, Hynes RO, Abdi R

Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection. Am J Transplant. 2007;7(5):1080-90 - PMID: 17359504 - DOI: 10.1111/j.1600-6143.2007.01757.x

Yamaura K, Boenisch O, Watanabe T, Ueno T, Vanguri V, Yang J, Tanaka K, Guleria I, Borst J, Zhai Y, Kupiec-Weglinski JW, Najafian N

Differential Requirement of CD27 Costimulatory Signaling for Naive Versus Alloantigen-Primed Effector/Memory CD8(+) T Cells. Am J Transplant. 2010;10(5):1210-20 - PMID: 20353477 - PMCID: PMC2889922 - DOI: 10.1111/j.1600-6143.2010.03089.x

Jurewicz M, Ueno T, Azzi J, Tanaka K, Murayama T, Yang S, Sayegh MH, Niimi M, Abdi R

Donor Antioxidant Strategy Prolongs Cardiac Allograft Survival by Attenuating Tissue Dendritic Cell Immunogenicity. Am J Transplant. 2010;11(2):348-355 - PMID: 21182586 - DOI: 10.1111/j.1600-6143.2010.03360.x

Starling RC, Stehlik J, Baran DA, Armstrong B, Stone JR, Ikle D, Morrison Y, Bridges ND, Putheti P, Strom TB, Bhasin M, Guleria I, Chandraker A, Sayegh M, Daly KP, Briscoe DM, Heeger PS,

Multicenter Analysis of Immune Biomarkers and Heart Transplant Outcomes: Results of the Clinical Trials in Organ Transplantation-05 Study. Am J Transplant. 2015;16(1):121-36 - PMID: 26260101 - PMCID: PMC4948061 - DOI: 10.1111/ajt.13422

Zhang Y, Dong H, Seeburg DP, Wojtkiewicz GR, Waterman P, Pulli B, Forghani R, Ali M, Iwamoto Y, Swirski FK, Chen JW

Multimodal Molecular Imaging Demonstrates Myeloperoxidase Regulation of Matrix Metalloproteinase Activity in Neuroinflammation. Mol Neurobiol. 2018;56(2):954-962 - PMID: 29808380 - PMCID: PMC6261713 - DOI: 10.1007/s12035-018-1137-2

Deshpande V, Zen Y, Chan JK, Yi EE, Sato Y, Yoshino T, Klöppel G, Heathcote JG, Khosroshahi A, Ferry JA, Aalberse RC, Bloch DB, Brugge WR, Bateman AC, Carruthers MN, Chari ST, Cheuk W, Cornell LD, Fernandez-Del Castillo C, Forcione DG, Hamilos DL, Kamisawa T, Kasashima S, Kawa S, Kawano M, Lauwers GY, Masaki Y, Nakanuma Y, Notohara K, Okazaki K, Ryu JK, Saeki T, Sahani DV, Smyrk TC, Stone JR, Takahira M, Webster GJ, Yamamoto M, Zamboni G, Umehara H, Stone JH

Consensus statement on the pathology of IgG4-related disease. Mod Pathol. 2012;25(9):1181-92 - PMID: 22596100 - DOI: 10.1038/modpathol.2012.72

Siddiquee Z, Smith RN, Stone JR

An elevated IgG4 response in chronic infectious aortitis is associated with aortic atherosclerosis. Mod Pathol. 2015;28(11):1428-34 - PMID: 26336884 - DOI: 10.1038/modpathol.2015.105

Michelson D, Chin WW, Dworkin RH, Freeman R, Herrmann DN, Mazitschek R, Pop-Busui R, Shaibani A, Vornov J, Jones M, Jarpe M, Hader B, Viera T, Hylan M, Kachmar T, Jones S

A randomized, double-blind, placebo-controlled study of histone deacetylase type 6 inhibition for the treatment of painful diabetic peripheral neuropathy. Pain Rep. 2023;8(6):e1114 - PMID: 37899940 - PMCID: PMC10611336 - DOI: 10.1097/PR9.0000000000001114

Law B, Curino A, Bugge TH, Weissleder R, Tung CH

Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter. Chem Biol. 2004;11(1):99-106 - PMID: 15112999 - DOI: 10.1016/j.chembiol.2003.12.017

Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L

Covalent Reactions of Wortmannin under Physiological Conditions. Chem Biol. 2007;14(3):321-8 - PMID: 17379147 - DOI: 10.1016/j.chembiol.2007.02.007

Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P

A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chem Biol. 2007;14:1221-31 - PMID: 18022561 - PMCID: PMC2785040 - DOI: 10.1016/j.chembiol.2007.10.005

Dong CK, Urgaonkar S, Cortese JF, Gamo FJ, Garcia-Bustos JF, Lafuente MJ, Patel V, Ross L, Coleman BI, Derbyshire ER, Clish CB, Serrano AE, Cromwell M, Barker RH, Dvorin JD, Duraisingh MT, Wirth DF, Clardy J, Mazitschek R

Identification and Validation of Tetracyclic Benzothiazepines as Plasmodium falciparum Cytochrome bc(1) Inhibitors. Chem Biol. 2011;18(12):1602-10 - PMID: 22195562 - PMCID: PMC3474356 - DOI: 10.1016/j.chembiol.2011.09.016

Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN

A robust small-molecule microarray platform for screening cell lysates. Chem Biol. 2006;13(5):493-504 - PMID: 16720270 - DOI: 10.1016/j.chembiol.2006.03.004

Kozloff KM, Weissleder R, Mahmood U

Non-Invasive Optical Detection of Bone Mineral. J Bone Miner Res. 2007;(22) 8:1208-1216 - PMID: 17488196 - DOI: 10.1359/jbmr.070504

Turan S, Fernandez-Rebollo E, Aydin C, Zoto T, Reyes M, Bounoutas G, Chen M, Weinstein LS, Erben RG, Marshansky V, Bastepe M

Postnatal establishment of allelic Gαs silencing as a plausible explanation for delayed onset of parathyroid hormone-resistance due to heterozygous Gαs disruption. J Bone Miner Res. 2014;29(3):749-60 - PMID: 23956044 - PMCID: PMC3926912 - DOI: 10.1002/jbmr.2070

Tokarz D, Martins JS, Petit ET, Lin CP, Demay MB, Liu ES

Hormonal regulation of osteocyte perilacunar and canalicular remodeling in the Hyp mouse model of XLH. J Bone Miner Res. 2017;33(3):499-509 - PMID: 29083055 - PMCID: PMC6005377 - DOI: 10.1002/jbmr.3327

Quillard T, Croce K, Jaffer FA, Weissleder R, Libby P

Molecular imaging of macrophage protease activity in cardiovascular inflammation in vivo. Thromb Haemostasis. 2011;105(5):828-36 - PMID: 21225096 - PMCID: PMC3087830 - DOI: 10.1160/TH10-09-0589

Ayers BC, Olverson G, Chukwudi C, Higuita ML, Ajenu E, Bolger-Chen M, Catricala J, Pitti A, Moshe YK, Kang J, Aguirre AD, Sundt TM, Michel E, Osho A, Tessier SN, Alireza Rabi S, D'Alessandro D

Video kinematics of an unloaded, ex-vivo beating heart can predict future loaded heart function. J Heart Lung Transplant. 2025;44(11):1823-1826 - PMID: 40716473 - DOI: 10.1016/j.healun.2025.07.023

Sosnovik DE, Nahrendorf M, Weissleder R

Targeted imaging of myocardial damage. Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275 - DOI: 10.1038/ncpcardio1115

Vinegoni C, Dubach JM, Thurber GM, Miller MA, Mazitschek R, Weissleder R

Advances in measuring single-cell pharmacokinetics and pharmacology in vivo. Drug Discov Today. 2015;20(9):1087-92 - PMID: 26024776 - PMCID: PMC4567932 - DOI: 10.1016/j.drudis.2015.05.011

Nordbeck P, Bauer WR, Fidler F, Warmuth M, Hiller KH, Nahrendorf M, Maxfield M, Wurtz S, Geistert W, Broscheit J, Jakob PM, Ritter O

Feasibility of Real-Time MRI With a Novel Carbon Catheter for Interventional Electrophysiology Circ Arrhythmia Electrophysiol. 2009;2(3):258-267 - PMID: 19808476 - DOI: 10.1161/CIRCEP.108.778357

Cook L, Sengelmann M, Winkler B, Nagl C, Koch S, Schlomann U, Slater EP, Miller MA, von Strandmann EP, Dorsam B, Preuber C, Bartsch JW

ADAM8-Dependent Extracellular Signaling in the Tumor Microenvironment Involves Regulated Release of Lipocalin 2 and MMP-9. Int J Mol Sci. 2022;23(4):ePub - PMID: 35216088 - PMCID: PMC8875419 - DOI: 10.3390/ijms23041976

Zeller MWG, Wang C, Keliher EJ, Wojtkiewicz GR, Aguirre A, Maresca K, Su C, Buckbinder L, Wang J, Nahrendorf M, Chen JW

Myeloperoxidase PET Imaging Tracks Intracellular and Extracellular Treatment Changes in Experimental Myocardial Infarction. Int J Mol Sci. 2023;24(6):ePub - PMID: 36982778 - PMCID: PMC10057533 - DOI: 10.3390/ijms24065704

Sosnovik DE, Nahrendorf M, Weissleder R

Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271 - DOI: 10.1007/s00395-008-0710-7

Nahrendorf M, Sosnovik DE, Weissleder R

MR-optical imaging of cardiovascular molecular targets. Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635 - DOI: 10.1007/s00395-008-0707-2

Lindau A, Härdtner C, Hergeth SP, Blanz KD, Dufner B, Hoppe N, Anto-Michel N, Kornemann J, Zou J, Gerhardt LM, Heidt T, Willecke F, Geis S, Stachon P, Wolf D, Libby P, Swirski FK, Robbins CS, McPheat W, Hawley S, Braddock M, Gilsbach R, Hein L, von Zur Mühlen C, Bode C, Zirlik A, Hilgendorf I

Atheroprotection through SYK inhibition fails in established disease when local macrophage proliferation dominates lesion progression. Basic Res Cardiol. 2016;111(2):20 - PMID: 26891724 - PMCID: PMC4759214 - DOI: 10.1007/s00395-016-0535-8

Härdtner C, Kornemann J, Krebs K, Ehlert CA, Jander A, Zou J, Starz C, Rauterberg S, Sharipova D, Dufner B, Hoppe N, Dederichs TS, Willecke F, Stachon P, Heidt T, Wolf D, von Zur Mühlen C, Madl J, Kohl P, Kaeser R, Boettler T, Pieterman EJ, Princen HMG, Ho-Tin-Noé B, Swirski FK, Robbins CS, Bode C, Zirlik A, Hilgendorf I

Inhibition of macrophage proliferation dominates plaque regression in response to cholesterol lowering. Basic Res Cardiol. 2020;115(6):78 - PMID: 33296022 - PMCID: PMC7725697 - DOI: 10.1007/s00395-020-00838-4

Truslow JG, Goto S, Homilius M, Mow C, Higgins JM, MacRae CA, Deo RC

Cardiovascular Risk Assessment Using Artificial Intelligence-Enabled Event Adjudication and Hematologic Predictors. Circ Cardiovasc Qual Outcomes. 2022;15(6):e008007 - PMID: 35477255 - PMCID: PMC9208816 - DOI: 10.1161/CIRCOUTCOMES.121.008007

Groen A, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison T

A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci. 2008;121(Pt 14):2293-300 - PMID: 18559893 - PMCID: PMC2902979 - DOI: 10.1242/jcs.024018

Zilberman Y, Ballestrem C, Carramusa L, Mazitschek R, Khochbin S, Bershadsky A

Regulation of microtubule dynamics by inhibition of the tubulin deacetylase HDAC6. J Cell Sci. 2009;122(Pt 19):3531-41 - PMID: 19737819 - DOI: 10.1242/jcs.046813

Tran AD, Marmo TP, Salam AA, Che S, Finkelstein E, Kabarriti R, Xenias HS, Mazitschek R, Hubbert C, Kawaguchi Y, Sheetz MP, Yao TP, Bulinski JC

HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions. J Cell Sci. 2007;120(Pt 8):1469-79 - PMID: 17389687 - DOI: 10.1242/jcs.03431

Ruan YC, Wang Y, Da Silva N, Kim B, Diao RY, Hill E, Brown D, Chan HC, Breton S

CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation via the ZONAB pathway. J Cell Sci. 2014;127(Pt 20):4396-408 - PMID: 25107366 - PMCID: PMC4197086 - DOI: 10.1242/jcs.148098

Li W, Jin WW, Tsuji K, Chen Y, Nomura N, Su L, Yui N, Arthur J, Cotecchia S, Păunescu TG, Brown D, Lu HAJ

Direct interaction of ezrin and AQP2 and its role in AQP2 trafficking. J Cell Sci. 2017;130(17):2914-2925 - PMID: 28754689 - PMCID: PMC5612225 - DOI: 10.1242/jcs.204842

Battistone MA, Spallanzani RG, Mendelsohn AC, Capen D, Nair AV, Brown D, Breton S

Novel role of proton-secreting epithelial cells in sperm maturation and mucosal immunity. J Cell Sci. 2019;133(5):ePub - PMID: 31636115 - PMCID: PMC7003979 - DOI: 10.1242/jcs.233239

Faris JE, Blaszkowsky LS, McDermott S, Guimaraes AR, Szymonifka J, Huynh MA, Ferrone CR, Wargo JA, Allen JN, Dias LE, Kwak EL, Lillemoe KD, Thayer SP, Murphy JE, Zhu AX, Sahani DV, Wo JY, Clark JW, Fernandez-Del Castillo C, Ryan DP, Hong TS

FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience. Oncologist. 2013;18(5):543-548 - PMID: 23657686 - PMCID: PMC3662845 - DOI: 10.1634/theoncologist.2012-0435

Schoenberg SO, Attenberger UI, Solomon SB, Weissleder R

Developing a Roadmap for Interventional Oncology. Oncologist. 2018;23(10):1162-1170 - PMID: 29959284 - PMCID: PMC6263130 - DOI: 10.1634/theoncologist.2017-0654

Jeng-Miller KW, Miller MA, Heier JS

Ocular Effects of MEK Inhibitor Therapy: Literature Review, Clinical Presentation, and Best Practices for Mitigation. Oncologist. 2024;29(5):e616-e621 - PMID: 38527005 - PMCID: PMC11067803 - DOI: 10.1093/oncolo/oyae014

Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA and Gropler RJ

Multimodality Cardiovascular Molecular Imaging, Part I Circ Cardiovasc Imaging. 2008;1(3):244-256 - PMID: 19808549 - DOI: 10.1161/CIRCIMAGING.108.824359

Nahrendorf M, Sosnovik D, French B, Swirski FK, Bengel F, Sadeghi MM, Lindner JR, Wu JC, Kraitchman DL, Fayad ZA, Sinusas AJ

Multimodality Cardiovascular Molecular Imaging, Part II Circ Cardiovasc Imaging. 2009;2:56-70 - PMID: 19808565 - PMCID: PMC2760054 - DOI: 10.1161/CIRCIMAGING.108.839092

Sosnovik DE, Wang R, Dai G, Wang T, Aikawa E, Novikov M, Rosenzweig A, Gilbert RJ and Wedeen VJ

Diffusion Spectrum MRI Tractography Reveals the Presence of a Complex Network of Residual Myofibers in Infarcted Myocardium Circ Cardiovasc Imaging. 2009;2:206-212 - PMID: 19808594 - PMCID: PMC2760045 - DOI: 10.1161/CIRCIMAGING.108.815050

Sosnovik DE, Nahrendorf M, Panizzi P, Matsui T, Aikawa E, Dai G, Li L, Reynolds F, Dorn GW, Weissleder R, Josephson L, Rosenzweig A

Molecular MRI Detects Low Levels of Cardiomyocyte Apoptosis in a Transgenic Model of Chronic Heart Failure. Circ Cardiovasc Imaging. 2009;2(6):468-475 - PMID: 19920045 - PMCID: PMC2782621 - DOI: 10.1161/CIRCIMAGING.109.863779

Sosnovik DE, Garanger E, Aikawa E, Nahrendorf M, Figuiredo JL, Dai G, Reynolds F, Rosenzweig A, Weissleder R, Josephson L

Molecular MRI of Cardiomyocyte Apoptosis With Simultaneous Delayed-Enhancement MRI Distinguishes Apoptotic and Necrotic Myocytes In Vivo: Potential for Midmyocardial Salvage in Acute Ischemia. Circ Cardiovasc Imaging. 2009;2(6):460-467 - PMID: 19920044 - PMCID: PMC2780438 - DOI: 10.1161/CIRCIMAGING.109.859678

Nordbeck P, Hiller KH, Fidler F, Warmuth M, Burkard N, Nahrendorf M, Jakob PM, Quick HH, Ertl G, Bauer WR, Ritter O

Feasibility of Contrast Enhanced and Non-Enhanced MRI for Intra- and Postprocedural Lesion Visualization in Interventional Electrophysiology: Animal Studies and Early Delineation of Isthmus Ablation Lesions in Patients with Typical Atrial Flutter. Circ Cardiovasc Imaging. 2011;4(3):282-94 - PMID: 21415125 - DOI: 10.1161/CIRCIMAGING.110.957670

Nahrendorf M

Imaging of infarct healing predicts left ventricular remodeling and evolution of heart failure: focus on protease activity. Circ Cardiovasc Imaging. 2011;4(4):351-3 - PMID: 21772011 - PMCID: PMC3141180 - DOI: 10.1161/CIRCIMAGING.111.966671

Huang S, Chen HH, Yuan H, Dai G, Schuhle DT, Mekkaoui C, Ngoy S, Liao R, Caravan P, Josephson L, Sosnovik DE

Molecular MRI of Acute Necrosis with a Novel DNA-Binding Gadolinium Chelate: Kinetics of Cell Death and Clearance in Infarcted Myocardium. Circ Cardiovasc Imaging. 2011;4(6):729-737 - PMID: 21836081 - PMCID: PMC3370828 - DOI: 10.1161/CIRCIMAGING.111.966374

Sosnovik DE, Nahrendorf M

Cells and Iron Oxide Nanoparticles on the Move: Magnetic Resonance Imaging of Monocyte Homing and Myocardial Inflammation in Patients With ST-Elevation Myocardial Infarction. Circ Cardiovasc Imaging. 2012;5(5):551-4 - PMID: 22991284 - PMCID: PMC3529959 - DOI: 10.1161/CIRCIMAGING.112.978932

Chen HH, Mekkaoui C, Cho H, Ngoy S, Marinelli B, Waterman P, Nahrendorf M, Liao R, Josephson L, Sosnovik DE

Fluorescence Tomography of Rapamycin-Induced Autophagy and Cardioprotection In Vivo. Circ Cardiovasc Imaging. 2013;6(3):441-7 - PMID: 23537953 - PMCID: PMC3805276 - DOI: 10.1161/CIRCIMAGING.112.000074

Ueno T, Dutta P, Keliher E, Leuschner F, Majmudar M, Marinelli B, Iwamoto Y, Figueiredo JL, Christen T, Swirski FK, Libby P, Weissleder R, Nahrendorf M

Nanoparticle PET-CT Detects Rejection and Immunomodulation in Cardiac Allografts. Circ Cardiovasc Imaging. 2013;6(4):568-73 - PMID: 23771986 - PMCID: PMC3734553 - DOI: 10.1161/CIRCIMAGING.113.000481

Taqueti VR, Di Carli MF, Jerosch-Herold M, Sukhova GK, Murthy VL, Folco EJ, Kwong RY, Ozaki CK, Belkin M, Nahrendorf M, Weissleder R, Libby P

Increased Microvascularization and Vessel Permeability Associate with Active Inflammation in Human Atheromata. Circ Cardiovasc Imaging. 2014;7(6):920-929 - PMID: 25170063 - PMCID: PMC4237630 - DOI: 10.1161/CIRCIMAGING.114.002113

Nahrendorf M, Swirski FK

Imaging systemic inflammation in patients with acute myocardial infarction. Circ Cardiovasc Imaging. 2014;7(5):762-4 - PMID: 25227235 - DOI: 10.1161/CIRCIMAGING.114.002410

Rischpler C, Dirschinger RJ, Nekolla SG, Kossmann H, Nicolosi S, Hanus F, van Marwick S, Kunze KP, Meinicke A, Götze K, Kastrati A, Langwieser N, Ibrahim T, Nahrendorf M, Schwaiger M, Laufwitz KL

Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome Circ Cardiovasc Imaging. 2016;9:e004316 - PMID: 27056601 - PMCID: PMC4826716 - DOI: 10.1161/CIRCIMAGING.115.004316

Vandoorne K, Nahrendorf M

Multiparametric Imaging of Organ System Interfaces. Circ Cardiovasc Imaging. 2017;10(4):ePub - PMID: 28360260 - PMCID: PMC5419074 - DOI: 10.1161/CIRCIMAGING.116.005613

Stein-Merlob AF, Hara T, McCarthy JR, Mauskapf A, Hamilton JA, Ntziachristos V, Libby P, Jaffer FA

Atheroma Susceptible to Thrombosis Exhibit Impaired Endothelial Permeability In Vivo as Assessed by Nanoparticle-Based Fluorescence Molecular Imaging. Circ Cardiovasc Imaging. 2017;10(5):ePub - PMID: 28487316 - PMCID: PMC5509162 - DOI: 10.1161/CIRCIMAGING.116.005813

Nahrendorf M, Hoyer FF, Meerwaldt AE, van Leent MMT, Senders ML, Calcagno C, Robson PM, Soultanidis G, Pérez-Medina C, Teunissen AJP, Toner YC, Ishikawa K, Fish K, Sakurai K, van Leeuwen EM, Klein ED, Sofias AM, Reiner T, Rohde D, Aguirre AD, Wojtkiewicz G, Schmidt S, Iwamoto Y, Izquierdo-Garcia D, Caravan P, Swirski FK, Weissleder R, Mulder WJM

Imaging Cardiovascular and Lung Macrophages With the Positron Emission Tomography Sensor 64Cu-Macrin in Mice, Rabbits, and Pigs. Circ Cardiovasc Imaging. 2020;13(10):e010586 - PMID: 33076700 - PMCID: PMC7583675 - DOI: 10.1161/CIRCIMAGING.120.010586

Nahrendorf M, Wiesmann F, Hiller K, Han H, Hu K, Waller C, Ruff J, Haase A, Ertl G, Bauer W

In vivo assessment of cardiac remodeling after myocardial infarction in rats by cine-magnetic resonance imaging. J Cardiovasc Magn Reson. 2001;2(3):171-80 - PMID: 11545114 - DOI: 10.3109/10976640009146565

Sosnovik DE, Caravan P

Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents J Cardiovasc Magn Reson. 2009;2:87-94

Sosnovik DE, Wang R, Dai G, Reese TG, Wedeen VJ

Diffusion MR tractography of the heart. J Cardiovasc Magn Reson. 2009;11(1):47 - PMID: 19912654 - PMCID: PMC2781805 - DOI: 10.1186/1532-429X-11-47

Mekkaoui C, Huang S, Chen HH, Dai G, Reese TG, Kostis WJ, Thiagalingam A, Maurovich-Horvat P, Ruskin JN, Hoffmann U, Jackowski MP, Sosnovik DE

Fiber architecture in remodeled myocardium revealed with a quantitative diffusion CMR tractography framework and histological validation. J Cardiovasc Magn Reson. 2012;14(1):70 - PMID: 23061749 - PMCID: PMC3506570 - DOI: 10.1186/1532-429X-14-70

Global Cardiovascular Magnetic Resonance Registry (GCMR) Investigators, Kwong RY, Petersen SE, Schulz-Menger J, Arai AE, Bingham SE, Chen Y, Choi YL, Cury RC, Ferreira VM, Flamm SD, Steel K, Bandettini WP, Martin ET, Nallamshetty L, Neubauer S, Raman SV, Schelbert EB, Valeti US, Cao JJ, Reichek N, Young AA, Fexon L, Pivovarov M, Ferrari VA, Simonetti OP

The global cardiovascular magnetic resonance registry (GCMR) of the society for cardiovascular magnetic resonance (SCMR): its goals, rationale, data infrastructure, and current developments. J Cardiovasc Magn Reson. 2017;19(1):23 - PMID: 28187739 - PMCID: PMC5303267 - DOI: 10.1186/s12968-016-0321-7

Law B, Weissleder R, Tung CH

Peptide-based Biomaterials for Protease-Enhanced Drug Delivery Biomacromolecules. 2006;7(4):1261-1265 - PMID: 16602747 - DOI: 10.1021/bm050920f

Law B, Tung CH

Structural modification of protease inducible preprogrammed nanofiber precursor. Biomacromolecules. 2008;9:421-5 - PMID: 18177006 - DOI: 10.1021/bm7012026

Yoshida S, Shimada M, Ueno T, Kitamura Y, Matsuzaki S, Nishikubo S, Nagae M, Nakanishi K, Murata J, Yoshino M

Successful endoscopic submucosal dissection of duodenal cancer. Endoscopy. 2008;40 Suppl 2:E132-3 - PMID: 18633861 - DOI: 10.1055/s-2007-995685

Yoshida S, Shimada M, Ueno T, Kato A, Yoshino M

Latex hand glove: a safe and convenient device for the endoscopic removal of foreign bodies. Endoscopy. 2008;40 Suppl 2:E195-6 - PMID: 18709613 - DOI: 10.1055/s-2008-1077420

Yoshida S, Shimada M, Ueno T, Yoshino M

Exuberant mucosal granulation by a self-expanding metal stent leading to complete closure of esophageal perforation. Endoscopy. 2008;40 Suppl 2:E244-5 - PMID: 18991221 - DOI: 10.1055/s-2008-1077526

Park KS, Charles RC, Ryan ET, Weissleder R*, Lee H*

Fluorescence polarization-based nucleic acid testing for rapid and cost-effective diagnosis of infectious disease Chem Eur J. 2015;21(46):16359-63 - PMID: 26420633 - PMCID: PMC4816641 - DOI: 10.1002/chem.201502934

Schellenberger EA, Bogdanov A Jr, Petrovsky A, Ntziachristos V, Weissleder R, Josephson L

Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy Neoplasia. 2003;5:187-92 - PMID: 12869301 - PMCID: PMC1502408 - DOI: 10.1016/S1476-5586(03)80050-7

Allport JR, Weissleder R

Murine Lewis lung carcinoma-derived endothelium expresses markers of endothelial activation and requires tumor-specific extracellular matrix in vitro Neoplasia. 2003;5:205-17 - PMID: 12869304 - PMCID: PMC1502407 - DOI: 10.1016/S1476-5586(03)80053-2

Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO

Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2 Neoplasia. 2002;4:501-9 - PMID: 12407444 - PMCID: PMC1503664 - DOI: 10.1038/sj.neo.7900265

Melder RJ, Munn LL, Stoll BR, Marecos EM, Baxter LT, Weissleder R, Jain RK

Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: comparison with physiologically based pharmacokinetic model Neoplasia. 2002;4:3-8 - PMID: 11922388 - PMCID: PMC1503314 - DOI: 10.1038/sj/neo/7900209

Ichikawa T, Hogemann D, Saeki Y, Tyminski E, Terada K, Weissleder R, Chiocca EA, Basilion JP

MRI of transgene expression: correlation to therapeutic gene expression Neoplasia. 2002;4:523-30 - PMID: 12407446 - PMCID: PMC1503666 - DOI: 10.1038/sj.neo.7900266

Bogdanov AA Jr, Lin CP, Simonova M, Matuszewski L, Weissleder R

Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment Neoplasia. 2002;4:228-36 - PMID: 11988842 - PMCID: PMC1531696 - DOI: 10.1038/sj/neo/7900238

Bogdanov A Jr, Marecos E, Cheng HC, Chandrasekaran L, Krutzsch HC, Roberts DD, Weissleder R

Treatment of experimental brain tumors with trombospondin-1 derived peptides: an in vivo imaging study Neoplasia. 1999;1:438-45 - PMID: 10933059 - PMCID: PMC1508110 - DOI: 10.1038/sj.neo.7900044

Hogemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP.

The transferrin receptor: a potential molecular imaging marker for human cancer. Neoplasia. 2003;5(6):495-506 - PMID: 14965443 - PMCID: PMC1502574 - DOI: 10.1016/s1476-5586(03)80034-9

Messerli SM, Prabhakar S, Tang Y, Shah K, Cortes ML, Murthy V, Weissleder R, Breakefield XO, Tung CH

A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. Neoplasia. 2004;6(2):95-105 - PMID: 15140398 - PMCID: PMC1502090 - DOI: 10.1593/neo.03214

Shinde Patil VR, Friedrich EB, Wolley AE, Gerszten RE, Allport JR, Weissleder R.

Bone Marrow-Derived lin(-)c-kit(+)Sca-1(+) Stem Cells Do Not Contribute to Vasculogenesis in Lewis Lung Carcinoma Neoplasia. 2005;7(3):234-40 - PMID: 15799823 - PMCID: PMC1501134 - DOI: 10.1593/neo.04523

Reichardt W, Hu-Lowe D, Torres D, Weissleder R, Bogdanov A Jr.

Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model Neoplasia. 2005;7(9):847-53 - PMID: 16229807 - PMCID: PMC1351316 - DOI: 10.1593/neo.05139

Funovics M, Montet X, Reynolds F, Weissleder R, Josephson L.

Nanoparticles for the Optical Imaging of Tumor E-selectin Neoplasia. 2005;7(10):904-11 - PMID: 16242073 - DOI: 10.1593/neo.05352

Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R

Novel Multiwavelength Microscopic Scanner for Mouse Imaging. Neoplasia. 2005;7(11):977-983 - PMID: 16331883 - PMCID: PMC1502018 - DOI: 10.1593/neo.05376

Sato F, Fukuhara H, Basilion JP

Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo. Neoplasia. 2005;7(9):838-46 - PMID: 16229806 - PMCID: PMC1501932 - DOI: 10.1593/neo.05145

Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L.

Nanoparticle Imaging of Integrins on Tumor Cells Neoplasia. 2006;8(3):214-222 - PMID: 16611415 - PMCID: PMC1578521 - DOI: 10.1593/neo.05769

Trehin R, Figueiredo JL, Pittet M, Weissleder R, Josephson L, Mahmood U.

Fluorescent Nanoparticle Uptake for Brain Tumor Visualization Neoplasia. 2006;8(4):302-311 - PMID: 16756722 - PMCID: PMC1600680 - DOI: 10.1593/neo.05751

Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL

In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006;8(9):772-80 - PMID: 16984734 - PMCID: PMC1584300 - DOI: 10.1593/neo.06331

Kelly KA, Waterman P, Weissleder R.

In vivo imaging of molecularly targeted phage Neoplasia. 2006;8 (12):1011-1018

Kock N, Kasmieh R, Weissleder R, Shah K

Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL. Neoplasia. 2007;9(5):435-42 - PMID: 17534449 - PMCID: PMC1877976 - DOI: 10.1593/neo.07223

Harisinghani M, Ross R, Guimaraes A, Weissleder R

Utility of a New Bolus-Injectable Nanoparticle for Clinical Cancer Staging Neoplasia. 2007;(9)12:1160-1165 - PMID: 18084623 - PMCID: PMC2134912 - DOI: 10.1593/neo.07940

Kelly K, Jones D

Isolation of a colon tumor specific binding peptide using phage display selection. Neoplasia. 2003;5:437-44 - PMID: 14670181 - PMCID: PMC1550331 - DOI: 10.1016/s1476-5586(03)80046-5

Perez JM, Grimm J, Josephson L, Weissleder R

Integrated nanosensors to determine levels and functional activity of human telomerase. Neoplasia. 2008;10(10):1066-72 - PMID: 18813356 - PMCID: PMC2546593 - DOI: 10.1593/neo.08350

Leimgruber A, Berger C, Cortez-Retamozo V, Etzrodt M, Newton A, Waterman P, Figueiredo JL, Kohler R, Elpek N, Mempel TR, Swirski FK, Nahrendorf M, Weissleder R, Pittet MJ

Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle Neoplasia. 2009;11(5):459-468 - PMID: 19412430 - PMCID: PMC2672160 - DOI: 10.1593/neo.09356

Reiner T, Lacy J, Keliher EJ, Yang KS, Ullal A, Kohler RH, Vinegoni C, Weissleder R

Imaging Therapeutic PARP Inhibition In Vivo through Bioorthogonally Developed Companion Imaging Agents Neoplasia. 2012;14(3):169-177 - PMID: 22496617 - PMCID: PMC3323895 - DOI: 10.1593/neo.12414

Ghazani AA, Castro CM, Gorbatov R, Lee H, Weissleder R

Sensitive and Direct Detection of Circulating Tumor Cells by Multimarker µ-Nuclear Magnetic Resonance. Neoplasia. 2012;14(5):388-95 - PMID: 22745585 - PMCID: PMC3384426 - DOI: 10.1596/neo.12696

Keliher EJ, Reiner T, Earley S, Klubnick J, Tassa C, Lee AJ, Ramaswamy S, Bardeesy N, Hanahan D, Depinho RA, Castro CM, Weissleder R

Targeting cathepsin e in pancreatic cancer by a small molecule allows in vivo detection. Neoplasia. 2013;15(7):684-93 - PMID: 23814481 - PMCID: PMC3689232 - DOI: 10.1593/neo.13276

Ali M, Fulci G, Grigalavicius M, Pulli B, Li A, Wojtkiewicz GR, Wang C, Hsieh KL, Linnoila JJ, Theodossiou TA, Chen JW

Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy. Neoplasia. 2022;26:100779 - PMID: 35247801 - PMCID: PMC8894277 - DOI: 10.1016/j.neo.2022.100779

van Solinge TS, Oh J, Abels E, Koch P, Breakefield XO, Weissleder R, Broekman MLD

Probing the glioma micro-environment: analysis using biopsy in combination with ultra-fast cyclic immunolabeling. Neoplasia. 2024;57:101051 - PMID: 39270598 - PMCID: PMC11415813 - DOI: 10.1016/j.neo.2024.101051

Frantz S, Hofmann U, Fraccarollo D, Schäfer A, Kranepuhl S, Hagedorn I, Nieswandt B, Nahrendorf M, Wagner H, Bayer B, Pachel C, Schön MP, Kneitz S, Bobinger T, Weidemann F, Ertl G, Bauersachs J

Monocytes/macrophages prevent healing defects and left ventricular thrombus formation after myocardial infarction. FASEB J. 2013;27(3):871-81 - PMID: 23159933 - DOI: 10.1096/fj.12-214049

Miller TE, Garcia Beltran WF, Bard AZ, Gogakos T, Anahtar MN, Astudillo MG, Yang D, Thierauf J, Fisch AS, Mahowald GK, Fitzpatrick MJ, Nardi V, Feldman J, Hauser BM, Caradonna TM, Marble HD, Ritterhouse LL, Turbett SE, Batten J, Georgantas NZ, Alter G, Schmidt AG, Harris JB, Gelfand JA, Poznansky MC, Bernstein BE, Louis DN, Dighe A, Charles RC, Ryan ET, Branda JA, Pierce VM, Murali MR, Iafrate AJ, Rosenberg ES, Lennerz JK

Clinical sensitivity and interpretation of PCR and serological COVID-19 diagnostics for patients presenting to the hospital. FASEB J. 2020;34(10):13877-13884 - PMID: 32856766 - PMCID: PMC7461169 - DOI: 10.1096/fj.202001700RR

Li JH, Forghani R, Bure L, Wojtkiewicz GR, Wu Y, Iwamoto Y, Ali M, Li A, Wang C, Jalali Motlagh N, Papadakis AI, Pusztaszeri MP, Spatz A, Curtin H, Cheng YS, Chen JW

Molecular immuno-imaging improves tumor detection in head and neck cancer. FASEB J. 2022;36(1):e22092 - PMID: 34919761 - PMCID: PMC9584652 - DOI: 10.1096/fj.202100864R

Kim DE, Jaffer FA, Weissleder R, Tung CH, Schellingerhout D.

Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis J Cereb Blood Flow Metab. 2005;25(2):226-33 - PMID: 15678125 - DOI: 10.1038/sj.jcbfm.9600023

Forghani R, Kim HJ, Wojtkiewicz GR, Bure L, Wu Y, Hayase M, Wei Y, Zheng Y, Moskowitz MA, Chen JW

Myeloperoxidase propagates damage and is a potential therapeutic target for subacute stroke. J Cereb Blood Flow Metab. 2014;35(3):485-93 - PMID: 25515211 - PMCID: PMC4348390 - DOI: 10.1038/jcbfm.2014.222

Kim HJ, Wei Y, Wojtkiewicz GR, Lee JY, Moskowitz MA, Chen JW

Reducing myeloperoxidase activity decreases inflammation and increases cellular protection in ischemic stroke. J Cereb Blood Flow Metab. 2018;39(9):1864-1877 - PMID: 29673284 - PMCID: PMC6727136 - DOI: 10.1177/0271678X18771978

Bouley R, Yui N, Terlouw A, Cheung PW, Brown D

Chlorpromazine Induces Basolateral Aquaporin-2 Accumulation via F-Actin Depolymerization and Blockade of Endocytosis in Renal Epithelial Cells. Cells. 2020;9(4):ePub - PMID: 32340337 - PMCID: PMC7226349 - DOI: 10.3390/cells9041057

Robbins CS, Swirski FK

The multiple roles of monocyte subsets in steady state and inflammation. Cell Mol Life Sci. 2010;67(16):2685-93 - PMID: 20437077 - PMCID: PMC11115635 - DOI: 10.1007/s00018-010-0375-x

Mahmood U, Weissleder R

Near-infrared optical imaging of proteases in cancer Mol Cancer Ther. 2003;2:489-96 - PMID: 12748311

Law B, Quinti L, Choi YD, Weissleder R, Tung CH

A Mitochondrial Targeted Fusion Peptide Exhibits Remarkable Cytotoxicity Mol Cancer Ther. 2006;5 (8):1944-1949 - PMID: 16928814 - DOI: 10.1158/1535-7163.MCT-05-0509

Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K

Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol Cancer Ther. 2008;7(11):3575-85 - PMID: 19001440 - PMCID: PMC2748233 - DOI: 10.1158/1535-7163.MCT-08-0640

Tannous BA, Christensen AP, Pike L, Wurdinger T, Perry KF, Saydam O, Jacobs AH, Garcia-Anoveros J, Weissleder R, Sena-Esteves M, Corey DP, Breakefield XO

Mutant Sodium Channel for Tumor Therapy. Mol Cancer Ther. 2009;17(5):810-9 - PMID: 19259066 - PMCID: PMC2751883 - DOI: 10.1038/mt.2009.33

Smith A, Blois J, Yuan H, Aikawa E, Ellson C, Figueiredo JL, Weissleder R, Kohler R, Yaffe MB, Cantley LC, Josephson L

The antiproliferative cytostatic effects of a self-activating viridin prodrug. Mol Cancer Ther. 2009;8(6):1666-1675 - PMID: 19509266 - PMCID: PMC2740925 - DOI: 10.1158/1535-7163.MCT-08-1012

Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B

Enhanced Antitumor Efficacy of Vasculostatin (Vstat120) Expressing Oncolytic HSV-1. Mol Cancer Ther. 2009;18(2):285-94 - PMID: 19844198 - PMCID: PMC2818668 - DOI: 10.1038/mt.2009.232

Emdad L, Sarkar D, Lee SG, Su ZZ, Yoo BK, Dash R, Yacoub A, Fuller CE, Shah K, Dent P, Bruce JN, Fisher PB

Astrocyte elevated gene-1: a novel target for human glioma therapy. Mol Cancer Ther. 2010;9(1):79-88 - PMID: 20053777 - PMCID: PMC3165052 - DOI: 10.1158/1535-7163.MCT-09-0752

Thurber G, Reiner T, Yang K, Kohler R, Weissleder R

Effect of Small Molecule Modification on Single Cell Pharmacokinetics of PARP Inhibitors. Mol Cancer Ther. 2014;13(4):986-95 - PMID: 24552776 - PMCID: PMC3981972 - DOI: 10.1158/1535-7163.MCT-13-0801

Oudin MJ, Barbier L, Schäfer C, Kosciuk T, Miller MA, Han S, Jonas O, Lauffenburger DA, Gertler FB

MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer. Mol Cancer Ther. 2016;16(1):143-155 - PMID: 27811011 - PMCID: PMC5359014 - DOI: 10.1158/1535-7163.MCT-16-0413

Framme C, Alt C, Schnell S, Brinkmann R, Lin CP

[Selective RPE laser treatment with a scanned cw laser beam in rabbits] Ophthalmologie. 2005;102(5):491-6 - PMID: 15883846 - DOI: 10.1007/s00347-004-1139-5

Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palu G, Irimia D, Toner M, Weissleder R, Poznansky MC

Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control. J Immunol. 2006;176(5):2902-14 - PMID: 16493048 - DOI: 10.4049/jimmunol.176.5.2902

Campanella GS, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewicz GR, Weissleder R, Luster AD

Oligomerization of CXCL10 Is Necessary for Endothelial Cell Presentation and In Vivo Activity. J Immunol. 2006;177:6991-8 - PMID: 17082614 - DOI: 10.4049/jimmunol.177.10.6991

Pittet M, Gati A, Le Gal F, Bioley G, Guillaume P, de Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Zippelius A

Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex. J Immunol. 2006;176:2330-6 - PMID: 16455990 - DOI: 10.4049/jimmunol.176.4.2330

Zippelius A, Bioley G, Le Gal F, Rufer N, Brandes M, Batard P, De Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Pittet M

Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J Immunol. 2004;172:2773-7 - PMID: 14978076 - DOI: 10.4049/jimmunol.172.5.2773

Pittet M, Rubio-Godoy V, Bioley G, Guillaume P, Batard P, Speiser D, Luescher I, Cerottini J, Romero P, Zippelius A

Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells. J Immunol. 2003;171:1844-9 - PMID: 12902485 - DOI: 10.4049/jimmunol.171.4.1844

Dietrich P, Le Gal F, Dutoit V, Pittet M, Trautman L, Zippelius A, Cognet I, Widmer V, Walker P, Michielin O, Guillaume P, Connerotte T, Jotereau F, Coulie P, Romero P, Cerottini J, Bonneville M, Valmori D

Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen. J Immunol. 2003;170:5103-9 - PMID: 12734356 - DOI: 10.4049/jimmunol.170.10.5103

Valmori D, Dutoit V, Schnuriger V, Quiquerez A, Pittet M, Guillaume P, Rubio-Godoy V, Walker P, Rimoldi D, Lienard D, Cerottini J, Romero P, Dietrich P

Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity. J Immunol. 2002;168:4231-40 - PMID: 11937585 - DOI: 10.4049/jimmunol.168.8.4231

Pittet M, Zippelius A, Speiser D, Assenmacher M, Guillaume P, Valmori D, Lienard D, Lejeune F, Cerottini J, Romero P

Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases. J Immunol. 2001;166:7634-40 - PMID: 11390521 - DOI: 10.4049/jimmunol.166.12.7634

Speiser D, Colonna M, Ayyoub M, Cella M, Pittet M, Batard P, Valmori D, Guillaume P, Lienard D, Cerottini J, Romero P

The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells. J Immunol. 2001;167:6165-70 - PMID: 11714776 - DOI: 10.4049/jimmunol.167.11.6165

Pittet M, Speiser D, Valmori D, Cerottini J, Romero P

Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression. J Immunol. 2000;164:1148-52 - PMID: 10640724 - DOI: 10.4049/jimmunol.164.3.1148

Alvarez D, Swirski F, Yang T, Fattouh R, Croitoru K, Bramson J, Stampfli M, Jordana M

Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues. J Immunol. 2006;176(4):2568-80 - PMID: 16456019 - DOI: 10.4049/jimmunol.176.4.2568

Gajewska B, Tafuri A, Swirski F, Walker T, Johnson J, Shea T, Shahinian A, Goncharova S, Mak T, Stampfli M, Jordana M

B7RP-1 is not required for the generation of Th2 responses in a model of allergic airway inflammation but is essential for the induction of inhalation tolerance. J Immunol. 2005;174(5):3000-5 - PMID: 15728513 - DOI: 10.4049/jimmunol.174.5.3000

Swirski F, Sajic D, Robbins C, Gajewska B, Jordana M, Stampfli M

Chronic exposure to innocuous antigen in sensitized mice leads to suppressed airway eosinophilia that is reversed by granulocyte macrophage colony-stimulating factor. J Immunol. 2002;169:3499-506 - PMID: 12244139 - DOI: 10.4049/jimmunol.169.7.3499

Romero P, Zippelius A, Kurth I, Pittet M, Touvrey C, Iancu E, Corthesy P, Devevre E, Speiser D, Rufer N

Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes. J Immunol. 2007;178(7):4112-9 - PMID: 17371966 - DOI: 10.4049/jimmunol.178.7.4112

Ito T*, Ueno T*, Clarkson MR, Yuan X, Jurewicz MM, Yagita H, Azuma M, Sharpe AH, Auchincloss H, Sayegh MH, Najafian N

Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo. J Immunol. 2005;174(11):6648-56 - PMID: 15905503 - DOI: 10.4049/jimmunol.174.11.6648

Izawa A, Yamaura K, Albin MJ, Jurewicz M, Tanaka K, Clarkson MR, Ueno T, Habicht A, Freeman GJ, Yagita H, Abdi R, Pearson T, Greiner DL, Sayegh MH, Najafian N

A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo. J Immunol. 2007;179(2):786-96 - PMID: 17617568 - DOI: 10.4049/jimmunol.179.2.786

Tanaka K, Albin MJ, Yuan X, Yamaura K, Habicht A, Murayama T, Grimm M, Waaga AM, Ueno T, Padera RF, Yagita H, Azuma M, Shin T, Blazar BR, Rothstein DM, Sayegh MH, Najafian N

PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol. 2007;179(8):5204-10 - PMID: 17911605 - PMCID: PMC2291549 - DOI: 10.4049/jimmunol.179.8.5204

Boenisch O, D'Addio F, Watanabe T, Elyaman W, Magee CN, Yeung MY, Padera RF, Rodig SJ, Murayama T, Tanaka K, Yuan X, Ueno T, Jurisch A, Mfarrej B, Akiba H, Yagita H, Najafian N

TIM-3: a novel regulatory molecule of alloimmune activation. J Immunol. 2010;185(10):5806-19 - PMID: 20956339 - PMCID: PMC3619947 - DOI: 10.4049/jimmunol.0903435

Xia Y, Cortez-Retamozo V, Niederkofler V, Salie R, Chen S, Samad TA, Hong CC, Arber S, Vyas JM, Weissleder R, Pittet MJ, Lin HY

Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages. J Immunol. 2011;186(3):1369-76 - PMID: 21187450 - PMCID: PMC3670585 - DOI: 10.4049/jimmunol.1002047

Zhi L, Kim P, Thompson BD, Pitsillides C, Bankovich AJ, Yun SH, Lin CP, Cyster JG, Wu MX

FTY720 Blocks Egress of T Cells in Part by Abrogation of Their Adhesion on the Lymph Node Sinus. J Immunol. 2011;187(5):2244-51 - PMID: 21788441 - PMCID: PMC3167479 - DOI: 10.4049/jimmunol.1100670

Marshansky V, Wang X, Bertrand R, Luo H, Duguid W, Chinnadurai G, Kanaan N, Vu MD, Wu J

Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells. J Immunol. 2001;166(5):3130-42 - PMID: 11207265 - DOI: 10.4049/jimmunol.166.5.3130

Riella LV*, Ueno T*, Batal I, De Serres SA, Bassil R, Elyaman W, Yagita H, Medina-Pestana JO, Chandraker A, Najafian N

Blockade of notch ligand delta1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation. J Immunol. 2011;187(9):4629-38 - PMID: 21949024 - PMCID: PMC3197868 - DOI: 10.4049/jimmunol.1004076

Li HW, Andreola G, Carlson AL, Shao S, Lin CP, Zhao G, Sykes M

Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation. J Immunol. 2015;195(3):1282-92 - PMID: 26085679 - PMCID: PMC4506852 - DOI: 10.4049/jimmunol.1401511

Misaghi S, Garris CS, Sun Y, Nguyen A, Zhang J, Sebrell A, Senger K, Yan D, Lorenzo MN, Heldens S, Lee WP, Xu M, Wu J, DeForge L, Sai T, Dixit VM, Zarrin AA

Increased targeting of donor switch region and IgE in Sgamma1-deficient B cells. J Immunol. 2010;185(1):166-73 - PMID: 20511552 - DOI: 10.4049/jimmunol.1000515

Hilgendorf I, Swirski FK

Folate receptor: a macrophage "achilles' heel"? J Am Heart Assoc. 2012;1(4):e004036 - PMID: 23130179 - PMCID: PMC3487350 - DOI: 10.1161/JAHA.112.004036

Secemsky EA, Butala NM, Kartoun U, Mahmood S, Wasfy JH, Kennedy KF, Shaw SY, Yeh RW

Use of Chronic Oral Anticoagulation and Associated Outcomes Among Patients Undergoing Percutaneous Coronary Intervention. J Am Heart Assoc. 2016;5(10):ePub - PMID: 27792650 - PMCID: PMC5121523 - DOI: 10.1161/JAHA.116.004310

Minami Y, Wang Z, Aguirre AD, Ong DS, Kim CJ, Uemura S, Soeda T, Lee H, Fujimoto J, Jang IK

Clinical Predictors for Lack of Favorable Vascular Response to Statin Therapy in Patients With Coronary Artery Disease: A Serial Optical Coherence Tomography Study. J Am Heart Assoc. 2017;6(11):e006241 - PMID: 29092845 - PMCID: PMC5721742 - DOI: 10.1161/JAHA.117.006241

Calcagno DM, Zhang C, Toomu A, Huang K, Ninh VK, Miyamoto S, Aguirre AD, Fu Z, Heller Brown J, King KR

SiglecF(HI) Marks Late-Stage Neutrophils of the Infarcted Heart: A Single-Cell Transcriptomic Analysis of Neutrophil Diversification. J Am Heart Assoc. 2021;10(4):e019019 - PMID: 33525909 - PMCID: PMC7955351 - DOI: 10.1161/JAHA.120.019019

Ott C, Pappritz K, Hegemann N, John C, Jeuthe S, McAlpine CS, Iwamoto Y, Lauryn JH, Klages J, Klopfleisch R, Van Linthout S, Swirski F, Nahrendorf M, Kintscher U, Grune T, Kuebler WM, Grune J

Spontaneous Degenerative Aortic Valve Disease in New Zealand Obese Mice. J Am Heart Assoc. 2021;10(23):e023131 - PMID: 34779224 - PMCID: PMC9075397 - DOI: 10.1161/JAHA.121.023131

Castro MM, Kim B, Games PD, Hill E, Neves CA, Serrão JE, Breton S, Machado-Neves M

Distribution pattern of ZO-1 and claudins in the epididymis of vampire bats. Tissue Barriers. 2020;8(3):1779526 - PMID: 32552339 - PMCID: PMC7549744 - DOI: 10.1080/21688370.2020.1779526

Bremer C, Ntziachristos V, Weitkamp B, Theilmeier G, Heindel W, Weissleder R.

Optical Imaging of Spontaneous Breast Tumors Using Protease Sensing Invest Radiol. 2005;(6):321-327 - PMID: 15905717 - DOI: 10.1097/01.rli.0000163797.23172.90

Frank H, Loewe R, Loewe C, Oberhuber G, Schwaighofer B, Huber K, Weissleder R

Efficacy of thrombolytic therapy in pulmonary embolism determined by MION-enhanced MRA: an experimental study in rabbits. Invest Radiol. 1998;33(12):853-7 - PMID: 9851818 - DOI: 10.1097/00004424-199812000-00002

Cheng HC, Khan MA, Bogdanov A, Kwong K, Weissleder R

Relative blood volume measurements by magnetic resonance imaging facilitate detection of testicular torsion. Invest Radiol. 1997;32(12):763-9 - PMID: 9406017 - DOI: 10.1097/00004424-199712000-00007

Schulze E, Ferrucci JT, Poss K, Lapointe L, Bogdanova A, Weissleder R

Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro. Invest Radiol. 1995;30(10):604-10 - PMID: 8557500 - DOI: 10.1097/00004424-199510000-00006

Weissleder R, Bogdanov A, Frank H, Nossiff N, Bogdanova A, Schaffer BK, Brady T, Wittenberg J

AUR Memorial Award 1993. A drug system (PDH) for interventional radiology. Synthesis, properties, and efficacy. Invest Radiol. 1993;28(12):1083-9 - PMID: 8307710 - DOI: 10.1097/00004424-199312000-00001

Reimer P, Weissleder R, Nickeleit V, Brady TJ

Animal models for magnetic resonance imaging research of the liver. Invest Radiol. 1992;27(5):390-3 - PMID: 1582824 - DOI: 10.1097/00004424-199205000-00014

Cohen RM, Franco RS, Smith EP, Higgins JM

When the A1c and the blood glucose don't match: how much is determined by race, by genetics, by differences in mean red blood cell age? J Clin Endocrinol Metab. 2019;104(3):707-710 - PMID: 30445523 - DOI: 10.1210/jc.2018-02409

Edelson PK, James KE, Leong A, Arenas J, Cayford M, Callahan MJ, Bernstein SN, Tangren JS, Hivert MF, Higgins JM, Nathan DM, Powe CE

Longitudinal Changes in the Relationship Between Hemoglobin A1c and Glucose Tolerance Across Pregnancy and Postpartum. J Clin Endocrinol Metab. 2020;105(5):e1999-2007 - PMID: 32010954 - PMCID: PMC7236626 - DOI: 10.1210/clinem/dgaa053

Powe CE, James K, Higgins JM

Response to Letter to the Editor from Marie Monlun: "Longitudinal changes in the relationship between Hemoglobin A1c and glucose tolerance across pregnancy and post-partum". J Clin Endocrinol Metab. 2021;106(1):e401-e402 - PMID: 32589732 - PMCID: PMC7765642 - DOI: 10.1210/clinem/dgaa402

Grüber G, Marshansky V

New insights into structure-function relationships between archeal ATP synthase (A1A0) and vacuolar type ATPase (V1V0). Bioessays. 2008;30(11-12):1096-109 - PMID: 18937357 - DOI: 10.1002/bies.20827

Valdez JM, Datta YH, Higgins JM, Wood DK

A microfluidic platform for simultaneous quantification of oxygen-dependent viscosity and shear thinning in sickle cell blood. APL Bioeng. 2019;3(4):046102 - PMID: 31803859 - PMCID: PMC6881198 - DOI: 10.1063/1.5118212

Baskaran JP, Weldy A, Guarin J, Munoz G, Shpilker PH, Kotlik M, Subbiah N, Wishart A, Peng Y, Miller MA, Cowen L, Oudin MJ

Cell shape, and not 2D migration, predicts extracellular matrix-driven 3D cell invasion in breast cancer. APL Bioeng. 2020;4(2):026105 - PMID: 32455252 - PMCID: PMC7202897 - DOI: 10.1063/1.5143779

Song TH, Cao M, Min J, Im H, Lee H, Lee K

Diffraction-informed deep learning for molecular-specific holograms of breast cancer cells. APL Bioeng. 2025;9(3):036107 - PMID: 40708806 - PMCID: PMC12289329 - DOI: 10.1063/5.0246495

Libby P, Nahrendorf M, Swirski FK

Monocyte heterogeneity in cardiovascular disease. Semin Immunopathol. 2013;35(5):553-62 - PMID: 23839097 - PMCID: PMC3755757 - DOI: 10.1007/s00281-013-0387-3

Swirski FK, Hilgendorf I, Robbins CS

From proliferation to proliferation: monocyte lineage comes full circle. Semin Immunopathol. 2014;36(2):137-48 - PMID: 24435095 - PMCID: PMC3991755 - DOI: 10.1007/s00281-013-0409-1

Chousterman BG, Swirski FK, Weber GF

Cytokine storm and sepsis disease pathogenesis. Semin Immunopathol. 2017;39(5):517-528 - PMID: 28555385 - DOI: 10.1007/s00281-017-0639-8

Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK

N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption. Mol Cell Biol. 2006;26(11):4185-200 - PMID: 16705170 - PMCID: PMC1489079 - DOI: 10.1128/MCB.01055-05

Gabriely G, Wurdinger T, Kesari S, Esau C, Burchard J, Linsley P, Krichevsky A

MiR-21 Promotes Glioma Invasion by Targeting MMP Regulators. Mol Cell Biol. 2008;28(17):5369-80 - PMID: 18591254 - PMCID: PMC2519720 - DOI: 10.1128/MCB.00479-08

Li X, Isono KI, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H

Mammalian Polycomblike Pcl2/Mtf2 is a novel regulatory component of PRC2 that can differentially modulate Polycomb activity at both the Hox gene cluster and at Cdkn2a genes. Mol Cell Biol. 2010;31(2):351-64 - PMID: 21059868 - PMCID: PMC3019975 - DOI: 10.1128/MCB.00259-10

de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H, Bradner JE, Mazitschek R, Kozikowski AP, Matthias P, Hancock WW

HDAC6 and HSP90 Control The Functions Of Foxp3+ T-Regulatory Cells. Mol Cell Biol. 2011;31(10):2066-78 - PMID: 21444725 - PMCID: PMC3133361 - DOI: 10.1128/MCB.05155-11

Li X, Isono K, Yamada D, Endo TA, Endoh M, Shinga J, Mizutani-Koseki Y, Otte AP, Casanova M, Kitamura H, Kamijo T, Sharif J, Ohara O, Toyada T, Bernstein BE, Brockdorff N, Koseki H

Mammalian Polycomb-Like Pcl2/Mtf2 Is a Novel Regulatory Component of PRC2 That Can Differentially Modulate Polycomb Activity both at the Hox Gene Cluster and at Cdkn2a Genes. Mol Cell Biol. 2014;34(14):2773 - PMID: 24951669 - PMCID: PMC4097671

Aragon Han P, Olson MT, Fazeli R, Prescott JD, Pai SI, Schneider EB, Tufano RP, Zeiger MA

The impact of molecular testing on the surgical management of patients with thyroid nodules. Ann Surg Oncol. 2014;21(6):1862-9 - PMID: 24522987 - DOI: 10.1245/s10434-014-3508-x

Fan KY, Gogineni H, Zaboli D, Lake S, Zahurak ML, Best SR, Levine MA, Tang M, Zinreich ES, Saunders JR, Califano JA, Blanco RG, Pai SI, Messing B, Ha PK

Comparison of acute toxicities in two primary chemoradiation regimens in the treatment of advanced head and neck squamous cell carcinoma. Ann Surg Oncol. 2012;19(6):1980-7 - PMID: 22290566 - PMCID: PMC3715048 - DOI: 10.1245/s10434-012-2219-4

Keung EZ, Krause KJ, Maxwell J, Morris CD, Crago AM, Houdek MT, Kane J, Lewis V, Callegaro D, Miller B, Lazar AJ, Gladdy R, Raut CP, Fabbri N, Al-Refaie W, Fairweather M, Wong SL, Roland CL

ASO Visual Abstract: Sentinel Lymph Node Biopsy for Extremity and Truncal Soft Tissue Sarcomas-A Systematic Review of the Literature. Ann Surg Oncol. 2023;30(2):970-971 - PMID: 36323987 - DOI: 10.1245/s10434-022-12754-z

Keung EZ, Krause KJ, Maxwell J, Morris CD, Crago AM, Houdek MT, Kane J, Lewis V, Callegaro D, Miller B, Lazar AJ, Gladdy R, Raut CP, Fabbri N, Al-Refaie W, Fairweather M, Wong SL, Roland CL

Sentinel Lymph Node Biopsy for Extremity and Truncal Soft Tissue Sarcomas: A Systematic Review of the Literature. Ann Surg Oncol. 2022;30(2):958-967 - PMID: 36307665 - DOI: 10.1245/s10434-022-12688-6

Parikh AS, Puram SV, Faquin WC, Richmon JD, Emerick KS, Deschler DG, Varvares MA, Tirosh I, Bernstein BE, Lin DT

Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis. Oral Oncol. 2019;99:104458 - PMID: 31704557 - PMCID: PMC7382966 - DOI: 10.1016/j.oraloncology.2019.104458

Pai SI, Zandberg DP, Strome SE

The role of antagonists of the PD-1:PD-L1/PD-L2 axis in head and neck cancer treatment. Oral Oncol. 2016;61:152-8 - PMID: 27503244 - PMCID: PMC5690560 - DOI: 10.1016/j.oraloncology.2016.08.001

Pai SI

Mission impossible: how HPV-associated head and neck cancers escape a primed immune response. Oral Oncol. 2013;49(8):723-5 - PMID: 23643070 - DOI: 10.1016/j.oraloncology.2013.03.453

Anderson KS, Gerber JE, D'Souza G, Pai SI, Cheng JN, Alam R, Kesiraju S, Chowell D, Gross ND, Haddad R, Gillison ML, Posner M

Biologic predictors of serologic responses to HPV in oropharyngeal cancer: The HOTSPOT study. Oral Oncol. 2015;51(8):751-8 - PMID: 26094591 - PMCID: PMC4982366 - DOI: 10.1016/j.oraloncology.2015.05.007

Pai SI, Jack Lee J, Carey TE, Westra WH, Ferrone S, Moore C, Mosunjac MB, Shin DM, Ferris RL, HNC SPORE HIV supplement consortium

HLA class I antigen processing machinery (APM) component expression and PD-1:PD-L1 pathway activation in HIV-infected head and neck cancers. Oral Oncol. 2017;77:92-97 - PMID: 29362132 - PMCID: PMC5786382 - DOI: 10.1016/j.oraloncology.2017.12.014

Smith DF, Maleki Z, Coughlan D, Gooi Z, Akpeng B, Ogawa T, Bishop JA, Frick KD, Agrawal N, Gourin CG, Ha PK, Koch WM, Richmon JD, Westra WH, Pai SI

Human papillomavirus status of head and neck cancer as determined in cytologic specimens using the hybrid-capture 2 assay. Oral Oncol. 2014;50(6):600-4 - PMID: 24630260 - PMCID: PMC4318229 - DOI: 10.1016/j.oraloncology.2014.02.011

Joseph AW, Ogawa T, Bishop JA, Lyford-Pike S, Chang X, Phelps TH, Westra WH, Pai SI

Molecular etiology of second primary tumors in contralateral tonsils of human papillomavirus-associated index tonsillar carcinomas. Oral Oncol. 2012;49(3):244-8 - PMID: 23062994 - PMCID: PMC3548989 - DOI: 10.1016/j.oraloncology.2012.09.009

Sanford NN, Hwang WL, Pike LRG, Lam AC, Royce TJ, Mahal BA

Trimodality therapy for HPV-positive oropharyngeal cancer: A population-based study: Trimodality therapy for HPV+ OPC. Oral Oncol. 2019;98:28-34 - PMID: 31536843 - PMCID: PMC7358785 - DOI: 10.1016/j.oraloncology.2019.09.009

Pike LRG, Hwang WL, Royce TJ, Sanford NN, Mahal BA

HPV status predicts for improved survival following chemotherapy in metastatic squamous cell carcinoma of the oropharynx. Oral Oncol. 2018;86:69-74 - PMID: 30409322 - DOI: 10.1016/j.oraloncology.2018.09.007

Park BJ, Mattox AK, Clayburgh D, Patel M, Bell RB, Yueh B, Leidner R, Xiao H, Couey M, Li S, Qin T, Sartor MA, Cairns B, MacDonough T, Halliwill K, Deschler D, Lin DT, Faquin WC, Sadow PM, Pai SI

Chemoradiation therapy alters the PD-L1 score in locoregional recurrent squamous cell carcinomas of the head and neck. Oral Oncol. 2022;135:106183 - PMID: 36215771 - PMCID: PMC10283355 - DOI: 10.1016/j.oraloncology.2022.106183

Leming M, Das S, Im H

Construction of a confounder-free clinical MRI dataset in the Mass General Brigham system for classification of Alzheimer's disease. Artif Intell Med. 2022;129:102309 - PMID: 35659387 - PMCID: PMC9295028 - DOI: 10.1016/j.artmed.2022.102309

Shah K, Breakefield XO

HSV Amplicon Vectors for Cancer Therapy. Curr Gene Ther. 2006;6(3):361-70 - PMID: 16787187 - DOI: 10.2174/156652306777592063

Sun CC, Vaja V, Babitt JL, Lin HY

Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation. Am J Hematol. 2012;87(4):392-400 - PMID: 22290531 - PMCID: PMC3653431 - DOI: 10.1002/ajh.23110

Golub MS, Hogrefe CE, Malka R, Higgins JM

Developmental Plasticity of red blood cell homeostasis. Am J Hematol. 2014;89(5):459-66 - PMID: 24415575 - PMCID: PMC4086753 - DOI: 10.1002/ajh.23666

Archer NM, Shmukler BE, Andolfo I, Vandorpe DH, Gnanasambandam R, Higgins JM, Rivera A, Fleming MD, Sachs F, Gottlieb PA, Iolascon A, Brugnara C, Alper SL, Nathan DG

Hereditary xerocytosis revisited. Am J Hematol. 2014;89(12):1142-1146 - PMID: 25044010 - PMCID: PMC4237618 - DOI: 10.1002/ajh.23799

Patel H, Patel H, Higgins JM

Modulation of Red Blood Cell Population Dynamics is a Fundamental Homeostatic Response to Disease. Am J Hematol. 2015;90(5):422-8 - PMID: 25691355 - PMCID: PMC4717489 - DOI: 10.1002/ajh.23982

Canali S, Wang CY, Zumbrennen-Bullough KB, Bayer A, Babitt JL

Bmp2 controls iron homeostasis in mice independent of Bmp6. Am J Hematol. 2017;92(11):1204-1213 - PMID: 28815688 - PMCID: PMC5986189 - DOI: 10.1002/ajh.24888

Lu X, Chaudhury A, Higgins JM, Wood DK

Oxygen-dependent flow of sickle trait blood as an in vitro therapeutic benchmark for sickle cell disease treatments. Am J Hematol. 2018;93(10):1227-1235 - PMID: 30033564 - PMCID: PMC6604607 - DOI: 10.1002/ajh.25227

Wang CY, Canali S, Bayer A, Dev S, Agarwal A, Babitt JL

Iron, erythropoietin, and inflammation regulate hepcidin in Bmp2-deficient mice, but serum iron fails to induce hepcidin in Bmp6-deficient mice. Am J Hematol. 2018;94(2):240-248 - PMID: 30478858 - PMCID: PMC6492930 - DOI: 10.1002/ajh.25366

Foy BH, Li A, McClung J, Ranganath R, Higgins JM

Data-driven physiologic thresholds for iron deficiency associated with hematologic decline. Am J Hematol. 2019;95(3):302-309 - PMID: 31849101 - DOI: 10.1002/ajh.25706

Conrad C, Dorzweiler K, Miller MA, Lauffenburger DA, Strik H, Bartsch JW

Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis. Fluids Barriers CNS. 2017;14(1):22 - PMID: 28806983 - PMCID: PMC5556623 - DOI: 10.1186/s12987-017-0070-5

Frenk NE, Spring L, Muzikansky A, Vadvala HV, Gurski JM, Henderson LE, Mino-Kenudson M, Ly A, Bardia A, Finkelstein D, Engelman J, Mueller PR, Juric D, Weissleder R

High-Content Biopsies Facilitate Molecular Analyses and Do Not Increase Complication Rates in Patients With Advanced Solid Tumors. JCO Precis Oncol. 2017;1:1-9 - PMID: 35172508 - DOI: 10.1200/PO.17.00081

Konstantinopoulos PA, Cai M, Lee EK, Krasner C, Campos SM, Liu JF, Horowitz NS, Shea M, Parsons HA, Wright AA, Bouberhan S, Penson RT, Yeku O, Hayes M, Sawyer H, Polak M, Castro CM, Cheng SC, Weipert CM, Matulonis UA

Serial Circulating Tumor DNA Sequencing to Monitor Response and Define Acquired Resistance to Letrozole/Abemaciclib in Endometrial Cancer. JCO Precis Oncol. 2025;9:e2400882 - PMID: 40209137 - DOI: 10.1200/PO-24-00882

Babitt JL, Lin HY

Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD. Am J Kidney Dis. 2010;55(4):726-41 - PMID: 20189278 - PMCID: PMC2905036 - DOI: 10.1053/j.ajkd.2009.12.030

Shayakul C, Breton S, Brown D, Alper SL

Gene therapy of inherited renal tubular disease. Am J Kidney Dis. 1999;34(2):374-9 - PMID: 10430991 - DOI: 10.1016/s0272-6386(99)70372-0

Pai SI, Faquin WC, Sadow PM, Pittet MJ, Weissleder R

New Technology on the Horizon: Fast Analytical Screening Technique FNA (FAST-FNA) Enables Rapid, Multiplex Biomarker Analysis in Head and Neck Cancers Cancer Cytopathol. 2020;128(11):782-791 - PMID: 32841527 - PMCID: PMC8276888 - DOI: 10.1002/cncy.22305

Pai SI, Faquin WC

Programmed cell death ligand 1 as a biomarker in head and neck cancer. Cancer Cytopathol. 2017;125(7):529-533 - PMID: 28472542 - PMCID: PMC5690557 - DOI: 10.1002/cncy.21872

Bishop JA, Maleki Z, Valsamakis A, Ogawa T, Chang X, Pai SI, Westra WH

Application of the hybrid capture 2 assay to squamous cell carcinomas of the head and neck: a convenient liquid-phase approach for the reliable determination of human papillomavirus status. Cancer Cytopathol. 2011;120(1):18-25 - PMID: 21751428 - PMCID: PMC3197962 - DOI: 10.1002/cncy.20175

Oh J, Yoo TY, Saal TM, Tsay L, Faquin WC, Carlson JCT, Deschler DG, Pai SI, Weissleder R

Multiplexed single-cell analysis of FNA allows accurate diagnosis of salivary gland tumors. Cancer Cytopathol. 2022;130(8):581-594 - PMID: 35666645 - PMCID: PMC9542730 - DOI: 10.1002/cncy.22594

Gultepe E, Reynoso FJ, Jhaveri A, Kulkarni P, Nagesha D, Ferris C, Harisinghani M, Campbell RB, Sridhar S

Monitoring of magnetic targeting to tumor vasculature through MRI and biodistribution. Nanomedicine (Lond). 2010;5(8):1173-82 - PMID: 21039195 - DOI: 10.2217/nnm.10.84

Chen HH, Feng Y, Zhang M, Chao W, Josephson L, Shaw SY, Sosnovik DE

Protective Effect of the Apoptosis-Sensing Nanoparticle AnxCLIO-Cy5.5. Nanomedicine (Lond). 2011;8(3):291-298 - PMID: 21704591 - PMCID: PMC3319055 - DOI: 10.1016/j.nano.2011.06.012

McCarthy JR, Jaffer FA

The role of nanomedicine in the imaging and therapy of thrombosis. Nanomedicine (Lond). 2011;6(8):1291-3 - PMID: 22026372 - PMCID: PMC3332076 - DOI: 10.2217/nnm.11.128

Weissleder R, Castro C

Interview: Nanomedicine in oncology: miniaturized means to an enormous end. Nanomedicine (Lond). 2011;6(9):1495-8 - PMID: 22077461 - DOI: 10.2217/nnm.11.138

McCarthy JR, Sazonova IY, Erdem SS, Hara T, Thompson BD, Patel P, Botnaru I, Lin CP, Reed GL, Weissleder R, Jaffer FA

Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy. Nanomedicine (Lond). 2012;7(7):1017-28 - PMID: 22348271 - PMCID: PMC3360120 - DOI: 10.2217/nnm.11.179

McCarthy JR

Book review: the handbook of nanomedicine (2nd edition). Nanomedicine (Lond). 2013;8(2):173-5 - PMID: 23394153

Ghazani AA, McDermott S, Pectasides M, Sebas M, Mino-Kenudson M, Lee H, Weissleder R, Castro CM

Comparison of select cancer biomarkers in human circulating and bulk tumor cells using magnetic nanoparticles and miniaturized micro-NMR system. Nanomedicine (Lond). 2013;9(7):1009-17 - PMID: 23570873 - PMCID: PMC4330975 - DOI: 10.1016/j.nano.2013.03.011

King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA

E2F3 plays an essential role in cardiac development and function. Cell Cycle. 2008;7(23):3775-80 - PMID: 19029823 - PMCID: PMC2723769 - DOI: 10.4161/cc.7.23.7240

Krukowski K, Ma J, Golonzhka O, Laumet GO, Gutti T, van Duzer JH, Mazitschek R, Jarpe MB, Heijnen CJ, Kavelaars A

HDAC6 inhibition effectively reverses chemotherapy-induced peripheral neuropathy. Pain. 2017;158(6):1126-1137 - PMID: 28267067 - PMCID: PMC5435512 - DOI: 10.1097/j.pain.0000000000000893

Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U

Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006;64(4):589-97 - PMID: 16996355 - DOI: 10.1016/j.gie.2006.02.048

Stone JR

Aortitis, periaortitis, and retroperitoneal fibrosis, as manifestations of IgG4-related systemic disease. Curr Opin Rheumatol. 2011;23(1):88-94 - PMID: 21037477 - DOI: 10.1097/BOR.0b013e3283412f7c

Unizony S, Stone JH, Stone JR

New treatment strategies in large-vessel vasculitis. Curr Opin Rheumatol. 2013;25(1):3-9 - PMID: 23114585 - DOI: 10.1097/BOR.0b013e32835b133a

Leong SP, Naxerova K, Keller L, Pantel K, Witte M

Molecular mechanisms of cancer metastasis via the lymphatic versus the blood vessels. Clin Exp Metastasis. 2021;39(1):159-179 - PMID: 34767139 - PMCID: PMC8967809 - DOI: 10.1007/s10585-021-10120-z

Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R

Molecular imaging of myocardial infarction. J Mol Cell Cardiol. 2006;41:921-933 - PMID: 17067633 - DOI: 10.1016/j.yjmcc.2006.09.008

Nahrendorf M

Macrophages in the infarct: fiery friends or friendly fire? J Mol Cell Cardiol. 2012;53(5):591-2 - PMID: 22975014 - DOI: 10.1016/j.yjmcc.2012.09.001

Hulsmans M, Sam F, Nahrendorf M

Monocyte and macrophage contributions to cardiac remodeling. J Mol Cell Cardiol. 2015;93:149-55 - PMID: 26593722 - PMCID: PMC4846552 - DOI: 10.1016/j.yjmcc.2015.11.015

Shao F, Yuan H, Josephson L, Weissleder R, Hilderbrand SA

Facile Synthesis of Monofunctional Pentamethine Carbocyanine Fluorophores. Dyes Pigm. 2011;90(2):119-122 - PMID: 21475610 - PMCID: PMC3070263 - DOI: 10.1016/j.dyepig.2010.12.008

Kim H, Lee S, Lee KW, Kim ES, Kim HM, Im H, Yoon HC, Ko JG, Kim E

Indolizine-based fluorescent compounds array for noninvasive monitoring of glucose in bio-fluids using on-device machine learning Dyes Pigm. 2023;215:2023 - DOI: 10.1016/j.dyepig.2023.111287

Wang L, Trebicka E, Fu Y, Ellenbogen S, Hong CC, Babitt JL, Lin HY, Cherayil BJ

The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease. Inflamm Bowel Dis. 2012;18(1):112-9 - PMID: 21351217 - PMCID: PMC3139830 - DOI: 10.1002/ibd.21675

Gounaris E, Martin J, Ishihara Y, Khan MW, Lee G, Sinh P, Chen EZ, Angarone M, Weissleder R, Khazaie K, Barrett TA

Fluorescence Endoscopy of Cathepsin Activity Discriminates Dysplasia from Colitis. Inflamm Bowel Dis. 2013;19(7):1339-1345 - PMID: 23591598 - PMCID: PMC4306589 - DOI: 10.1097/MIB.0b013e318281f3f8

Ananthakrishnan AN, Cagan A, Gainer VS, Cai T, Cheng SC, Savova G, Chen P, Szolovits P, Xia Z, De Jager PL, Shaw SY, Churchill S, Karlson EW, Kohane I, Plenge RM, Murphy SN, Liao KP

Normalization of Plasma 25-Hydroxy Vitamin D Is Associated with Reduced Risk of Surgery in Crohn's Disease. Inflamm Bowel Dis. 2013;19(9):1921-1927 - PMID: 23751398 - PMCID: PMC3720838 - DOI: 10.1097/MIB.0b013e3182902ad9

Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP, Xavier RJ

Common Genetic Variants Influence Circulating Vitamin D Levels in Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2015;21(11):2507-2514 - PMID: 26241000 - PMCID: PMC4615315 - DOI: 10.1097/MIB.0000000000000524

Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Murphy SN, Liao KP, Kohane I

Identification of Nonresponse to Treatment Using Narrative Data in an Electronic Health Record Inflammatory Bowel Disease Cohort. Inflamm Bowel Dis. 2016;22(1):151-158 - PMID: 26332313 - PMCID: PMC4772891 - DOI: 10.1097/MIB.0000000000000580

Ananthakrishnan AN, Cagan A, Cai T, Gainer VS, Shaw SY, Savova G, Churchill S, Karlson EW, Kohane I, Liao KP, Murphy SN

Comparative Effectiveness of Infliximab and Adalimumab in Crohn's Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2016;22(4):880-885 - PMID: 26933751 - PMCID: PMC4792716 - DOI: 10.1097/MIB.0000000000000754

Byun H, Hillman TR, Higgins JM, Diez-Silva M, Peng Z, Dao M, Dasari RR, Suresh S, Park Y

Optical measurement of biomechanical properties of individual erythrocytes from a sickle cell patient. Acta Biomater. 2012;8(11):4130-8 - PMID: 22820310 - PMCID: PMC3576574 - DOI: 10.1016/j.actbio.2012.07.011

Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC

Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006;12(5):797-806 - PMID: 16556935 - PMCID: PMC1440893 - DOI: 10.1261/rna.2300406

Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bunemann M

Kinetics of G-protein-coupled receptor signals in intact cells. Brit J Pharmacol. 2008;153 Suppl 1:S125-32 - PMID: 18193071 - PMCID: PMC2268076 - DOI: 10.1038/sj.bjp.0707656

Bredow S, Lewin M, Hofmann B, Marecos E, Weissleder R

Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin Eur J Cancer. 2000;36:675-81 - PMID: 10738134 - DOI: 10.1016/s0959-8049(99)00335-4

Weissleder R, Cheng HC, Marecos E, Kwong K, Bogdanov A

Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions. Eur J Cancer. 1998;34(9):1448-54 - PMID: 9849430 - DOI: 10.1016/s0959-8049(98)00195-6

Stieber F, Grether U, Mazitschek R, Soric N, Giannis A, Waldmann H

Multistep solid-phase synthesis of an antibiotic and receptor tyrosine kinase inhibitors using the traceless phenylhydrazide linker. Chemistry. 2003;9(14):3282-91 - PMID: 12866072 - DOI: 10.1002/chem.200304821

Vunnam S, Reddy A, Mazitschek R, Lukens AK, Wirth DF, Li L, Naumov P, O'Connor MJ, Al-Tel TH

Intramolecular Diaza-Diels-Alder Protocol: A Novel Diastereoselective and Modular One-Step Synthesis of Constrained Polycyclic Frameworks. Chemistry. 2017;23(17):4137-4148 - PMID: 27997727 - DOI: 10.1002/chem.201605231

Vunnam S, Mazitschek R, Kariem NM, Reddy A, Rabeh W, Li L, O'Connor MJ, Al-Tel TH

Modular Bi-Directional One-Pot Strategies for the Diastereoselective Synthesis of Structurally Diverse Collections of Constrained β-Carboline-Benzoxazepines. Chemistry. 2017;23(57):14182-14192 - PMID: 28770556 - DOI: 10.1002/chem.201702495

Kuba W, Sohr B, Keppel P, Svatunek D, Humhal V, Stöger B, Goldeck M, Carlson JCT, Mikula H

Oxidative Desymmetrization Enables the Concise Synthesis of a trans-Cyclooctene Linker for Bioorthogonal Bond-Cleavage. Chemistry. 2022;29(3):e202203069 - PMID: 36250260 - PMCID: PMC10098836 - DOI: 10.1002/chem.202203069

van der Laan AM, Nahrendorf M, Piek JJ

Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response. Heart. 2012;98(18):1384-90 - PMID: 22904145 - DOI: 10.1136/heartjnl-2012-301623

Jaffe AT, Pallarès-López R, Raines JK, Aguirre AD, Anthony BW

Noninvasive Quantitative Compression Ultrasound Central Venous Pressure: A Clinical Pilot Study. BME Front. 2025;6:0115 - PMID: 40110344 - PMCID: PMC11922486 - DOI: 10.34133/bmef.0115

Speiser D, Lienard D, Pittet M, Batard P, Rimoldi D, Guillaume P, Cerottini J, Romero P

In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells. Eur J Immunol. 2002;32:731-41 - PMID: 11870617 - DOI: 10.1002/1521-4141(200203)32:3<731::AID-IMMU731>3.0.CO;2-H

Speiser D, Migliaccio M, Pittet M, Valmori D, Lienard D, Lejeune F, Reichenbach P, Guillaume P, Lascher I, Cerottini J, Romero P

Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells. Eur J Immunol. 2001;31:459-66 - PMID: 11180110 - DOI: 10.1002/1521-4141(200102)31:2<459::aid-immu459>3.0.co;2-y

Speiser D, Valmori D, Rimoldi D, Pittet M, Lienard D, Cerundolo V, MacDonald H, Cerottini J, Romero P

CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients. Eur J Immunol. 1999;29:1990-9 - PMID: 10382762 - DOI: 10.1002/(SICI)1521-4141(199906)29:06<1990::AID-IMMU1990>3.0.CO;2-9

Swirski F, Gajewska B, Robbins C, D'Sa A, Johnson J, Pouladi M, Inman M, Stampfli M

Concomitant airway expression of granulocyte-macrophage colony-stimulating factor and decorin, a natural inhibitor of transforming growth factor-beta, breaks established inhalation tolerance. Eur J Immunol. 2004;34(9):2375-86 - PMID: 15307170 - DOI: 10.1002/eji.200425012

Pittet MJ, Swirski FK

Monocytes link atherosclerosis and cancer. Eur J Immunol. 2011;41(9):2519-22 - PMID: 21952809 - PMCID: PMC3817567 - DOI: 10.1002/eji.201141727

Ueno T, Yeung MY, McGrath M, Yang S, Zaman N, Snawder B, Padera RF, Magee CN, Gorbatov R, Hashiguchi M, Azuma M, Freeman GJ, Sayegh MH, Najafian N

Intact B7-H3 signaling promotes allograft prolongation through preferential suppression of Th1 effector responses. Eur J Immunol. 2012;42(9):2343-53 - PMID: 22733595 - PMCID: PMC3822046 - DOI: 10.1002/eji.201242501

Galande A, Weissleder R, Tung CH.

An Effective Method of On-Resin Disulfide Bond Formation in Peptides J Comb Chem. 2005;7:174-177 - PMID: 15762743 - DOI: 10.1021/cc049839r

Garanger E, Blois J, Hilderbrand SA, Shao F, Josephson L

Divergent Oriented Synthesis For the Design of Reagents for Protein Conjugation. J Comb Chem. 2009;12(1):57-64 - PMID: 19928910 - PMCID: PMC2877490 - DOI: 10.1021/cc900141b

Weissleder R, Marfil A, Martinez HR, Rangel-Guerra RA

Limb girdle type muscular dystrophy associated with a Wolff-Parkinson-White syndrome. J Neurol Neurosurg Psych. 1987;50(4):500-1 - PMID: 3585373 - PMCID: PMC1031899 - DOI: 10.1136/jnnp.50.4.500

Rabkin-Aikawa E, Aikawa M, Farber M, Kratz J, Garcia-Cardena G, Kouchoukos N, Mitchell M, Jonas R, Schoen F

Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site. J Thorac Cardiovasc Surg. 2004;128:552-61 - PMID: 15457156 - DOI: 10.1016/j.jtcvs.2004.04.016

Ong CS, Reinertsen E, Sun H, Moonsamy P, Mohan N, Funamoto M, Kaneko T, Shekar PS, Schena S, Lawton JS, D'Alessandro DA, Westover MB, Aguirre AD, Sundt TM

Prediction of operative mortality for patients undergoing cardiac surgical procedures without established risk scores. J Thorac Cardiovasc Surg. 2021;165(4):1449-1459.e15 - PMID: 34607725 - PMCID: PMC8918430 - DOI: 10.1016/j.jtcvs.2021.09.010

Jeong MH, Han H, Lagares D, Im H

Recent Advances in Molecular Diagnosis of Pulmonary Fibrosis for Precision Medicine ACS Pharmacol Transl Sci. 2022;5(8):520-538 - PMID: 35983278 - PMCID: PMC9379941 - DOI: 10.1021/acsptsci.2c00028

Wagner CA, L

A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse. Pflug Arch Eur J Phy. 2003;446(5):623-32 - PMID: 12748863 - DOI: 10.1007/s00424-003-1082-3

Hegemann N, Sang P, Kim JH, Koçana C, Momin N, Klages J, Kucherenko MM, Knosalla C, O'Brien B, Simmons S, Nahrendorf M, Kuebler WM, Grune J

Ultrasonographic assessment of pulmonary and central venous congestion in experimental heart failure. Am J Physiol Heart Circ Physiol. 2023;326(2):H433-H440 - PMID: 38099848 - PMCID: PMC11219047 - DOI: 10.1152/ajpheart.00735.2023

Knierim M, Bommer T, Paulus M, Riedl D, Fink S, Pöppl A, Reetz F, Wang P, Maier L, Voigt N, Nahrendorf M, Sossalla S, Streckfuss-Bömeke K, Pabel S

Cellular calcium handling and electrophysiology are modulated by chronic physiological pacing in human induced pluripotent stem cell-derived cardiomyocytes. Am J Physiol Heart Circ Physiol. 2024;327(5):H1244-H1254 - PMID: 39302711 - DOI: 10.1152/ajpheart.00536.2024

Petrozziello T, Motlagh NJ, Monsanto RZB, Lei D, Murcar MG, Penney EB, Bragg DC, Fernandez-Cerado C, Legarda GP, Sy M, Muñoz E, Ang MC, Diesta CCE, Zhang C, Tanzi RE, Qureshi IA, Chen JW, Sadri-Vakili G

Targeting Myeloperoxidase to Reduce Neuroinflammation in X-Linked Dystonia Parkinsonism. CNS Neurosci Ther. 2024;30(11):e70109 - PMID: 39500625 - PMCID: PMC11537767 - DOI: 10.1111/cns.70109

Swirski F, Gajewska B, Alvarez D, Ritz S, Cundall M, Cates E, Coyle A, Gutierrez-Ramos J, Inman M, Jordana M, Stampfli M

Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice. Clin Exp Allergy. 2002;32:411-21 - PMID: 11940072 - DOI: 10.1046/j.1365-2222.2002.01291.x

Piccirillo G M, Binda E, Fiocco R, Vescovi L, Shah K

Brain cancer stem cells. J Mol Med. 2009;87(11):1087-95 - PMID: 19784875 - DOI: 10.1007/s00109-009-0535-3

Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM

Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells. J Gen Physiol. 2004;124(4):395-407 - PMID: 15452200 - PMCID: PMC2233909 - DOI: 10.1085/jgp.200409120

Li C, Breton S, Morrison R, Cannon CL, Emma F, Sanchez-Olea R, Bear C, Strange K

Recombinant pICln forms highly cation-selective channels when reconstituted into artificial and biological membranes. J Gen Physiol. 1998;112(6):727-36 - PMID: 9834142 - PMCID: PMC2229450 - DOI: 10.1085/jgp.112.6.727

Xu Y, Ashline D, Liu L, Tassa C, Shaw SY, Ravid K, Layne MD, Reinhold V, Robbins PW

The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis. J Lipid Res. 2014;56(2):266-76 - PMID: 25528754 - PMCID: PMC4306681 - DOI: 10.1194/jlr.M053017

Stokes KL, Cortez-Retamozo V, Acosta J, Lauderback B, Robles-Oteiza C, Cicchini M, Pittet MJ, Feldser DM

Natural killer cells limit the clearance of senescent lung adenocarcinoma cells. Oncogenesis. 2019;8(4):24 - PMID: 30936429 - PMCID: PMC6443683 - DOI: 10.1038/s41389-019-0133-3

Pojoga LH, Romero JR, Yao TM, Loutraris P, Ricchiuti V, Coutinho P, Guo C, Lapointe N, Stone JR, Adler GK, Williams GH

Caveolin-1 Ablation Reduces the Adverse Cardiovascular Effects of N-{omega}-Nitro-L-Arginine Methyl Ester and Angiotensin II. Endocrinology. 2010;151(3):1236-46 - PMID: 20097717 - PMCID: PMC2840694 - DOI: 10.1210/en.2009-0514

Liu Z, Segawa H, Aydin C, Reyes M, Erben RG, Weinstein LS, Chen M, Marshansky V, Frohlich LF, Bastepe M

Transgenic Overexpression of the Extra-Large Gs{alpha} Variant XL{alpha}s Enhances Gs{alpha}-Mediated Responses in the Mouse Renal Proximal Tubule in Vivo. Endocrinology. 2011;152(4):1222-33 - PMID: 21303955 - PMCID: PMC3060637 - DOI: 10.1210/en.2010-1034

Chen S, Webber MJ, Vilardaga JP, Khatri A, Brown D, Ausiello DA, Lin HY, Bouley R

Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand. Endocrinology. 2011;152(10):3893-904 - PMID: 21828182 - PMCID: PMC3176653 - DOI: 10.1210/en.2011-1049

Xia Y, Sidis Y, Mukherjee A, Samad TA, Brenner G, Woolf CJ, Lin HY, Schneyer A

Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis. Endocrinology. 2005;146(8):3614-21 - PMID: 15890774 - PMCID: PMC1351303 - DOI: 10.1210/en.2004-1676

Jun HJ, Roy J, Smith TB, Wood LB, Lane K, Woolfenden S, Punko D, Bronson RT, Haigis KM, Breton S, Charest A

ROS1 Signaling Regulates Epithelial Differentiation in the Epididymis. Endocrinology. 2014;155(9):3661-73 - PMID: 24971615 - PMCID: PMC4138574 - DOI: 10.1210/en.2014-1341

Canali S, Core AB, Zumbrennen-Bullough KB, Merkulova M, Wang CY, Schneyer A, Pietrangelo A, Babitt JL

Activin B induces noncanonical SMAD1/5/8 signaling via BMP type I receptors in hepatocytes: evidence for a role in hepcidin induction by inflammation in male mice. Endocrinology. 2016;157(3):1146-62 - PMID: 26735394 - PMCID: PMC4769363 - DOI: 10.1210/en.2015-1747

Canali S, Vecchi C, Garuti C, Montosi G, Babitt JL, Pietrangelo A

The SMAD pathway is required for hepcidin response during endoplasmic reticulum stress. Endocrinology. 2016;157(10):3935-3945 - PMID: 27483343 - PMCID: PMC5045507 - DOI: 10.1210/en.2016-1258

Hilderbrand S, Lippard S

Cobalt chemistry with mixed aminotroponiminate salicylaldiminate ligands: synthesis, characterization, and nitric oxide reactivity. Inorg Chem. 2004;43:4674-82 - PMID: 15257596 - DOI: 10.1021/ic049776h

Hilderbrand S, Lippard S

Nitric oxide reactivity of fluorophore coordinated carboxylate-bridged diiron(II) and dicobalt(II) complexes. Inorg Chem. 2004;43:5294-301 - PMID: 15310207 - DOI: 10.1021/ic049649l

Nolan E, Burdette S, Harvey J, Hilderbrand S, Lippard S

Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorg Chem. 2004;43:2624-35 - PMID: 15074981 - DOI: 10.1021/ic035158+

Brown D, Breton S, Ausiello DA, Marshansky V

Sensing, Signaling and Sorting Events in Kidney Epithelial Cell Physiology. Traffic. 2009;10(3):275-84 - PMID: 19170982 - PMCID: PMC2896909 - DOI: 10.1111/j.1600-0854.2008.00867.x

Beaulieu V, Da Silva N, Pastor-Soler N, Brown CR, Smith PJ, Brown D, Breton S

Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling. J Biol Chem. 2005;280(9):8452-63 - PMID: 15591047 - DOI: 10.1074/jbc.M412750200

Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D

Heat shock protein 70 interacts with aquaporin-2 (AQP2) and regulates its trafficking. J Biol Chem. 2007;282(39):28721-32 - PMID: 17636261 - DOI: 10.1074/jbc.M611101200

Pietrement C, Da Silva N, Silberstein C, James M, Marsolais M, Van Hoek A, Brown D, Pastor-Soler N, Ameen N, Laprade R, Ramesh V, Breton S

Role of NHERF1, CFTR and cAMP in the regulation of aquaporin 9 J Biol Chem. 2008;283:2986-96 - PMID: 18055461 - DOI: 10.1074/jbc.M704678200

Johnson E, Lee Y, Sander T, Rabkin E, Schoen F, Kaushal S, Bischoff J

NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells. J Biol Chem. 2003;278:1686-92 - PMID: 12427739 - PMCID: PMC2813494 - DOI: 10.1074/jbc.M210250200

Shah K, Vervoort J, de Vries S

Role of threonines in the Arabidopsis thaliana somatic embryogenesis receptor kinase 1 activation loop in phosphorylation. J Biol Chem. 2001;276(44):41263-9 - PMID: 11509554 - DOI: 10.1074/jbc.M102381200

Xia Y, Yu P, Sidis Y, Beppu H, Bloch K, Schneyer A, Lin H

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem. 2007;282(25):18129-40 - PMID: 17472960 - DOI: 10.1074/jbc.M701679200

Babitt J, Zhang Y, Samad T, Xia Y, Tang J, Campagna J, Schneyer A, Woolf C, Lin HY

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem. 2005;280(33):29820-7 - PMID: 15975920 - DOI: 10.1074/jbc.M503511200

del Re E, Sidis Y, Fabrizio D, Lin HY, Schneyer A

Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system. J Biol Chem. 2004;279(51):53126-35 - PMID: 15475360 - DOI: 10.1074/jbc.M408090200

del Re E, Babitt J, Pirani A, Schneyer A, Lin HY

In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2. J Biol Chem. 2004;279(21):22765-72 - PMID: 14996829 - DOI: 10.1074/jbc.M401350200

Hasler U, Nunes P, Bouley R, Lu HA, Matsuzaki T, Brown D

Acute hypertonicity alters aquaporin-2 trafficking and induces a MAP kinase-dependent accumulation at the plasma membrane of renal epithelial cells. J Biol Chem. 2008;283(39):26643-61 - PMID: 18664568 - PMCID: PMC2546545 - DOI: 10.1074/jbc.M801071200

Schuetz A, Min J, Allali-Hassani A, Schapira M, Shuen M, Loppnau P, Mazitschek R, Kwiatkowski N, Lewis T, Maglathin R, McLean T, Bochkarev A, Plotnikov A, Vedadi M, Arrowsmith C

Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. J Biol Chem. 2008;283(17):11355-63 - PMID: 18285338 - PMCID: PMC2431080 - DOI: 10.1074/jbc.M707362200

Kawada J, Zou P, Mazitschek R, Bradner JE, Cohen JI

Tubacin kills Epstein-Barr virus (EBV)-Burkitt lymphoma cells by inducing reactive oxygen species and EBV lymphoblastoid cells by inducing apoptosis. J Biol Chem. 2009;284(25):17102-9 - PMID: 19386607 - PMCID: PMC2719348 - DOI: 10.1074/jbc.M809090200

Tharp A, Laha M, Panizzi P, Thompson M, Fuentes-Prior P, Bock P

Plasminogen substrate recognition by the streptokinase-plasminogen catalytic complex is facilitated by Arg253, Lys256, and Lys257 in the streptokinase beta-domain and Kringle 5 of the substrate. J Biol Chem. 2009;284(29):19511-21 - PMID: 19473980 - PMCID: PMC2740577 - DOI: 10.1074/jbc.M109.005512

Wiles KG, Panizzi P, Kroh HK, Bock PE

Skizzle is a novel plasminogen and plasmin binding protein from Streptococcus agalactiae that targets proteins of human fibrinolysis to promote plasmin generation. J Biol Chem. 2010;285(27):21153-64 - PMID: 20435890 - PMCID: PMC2898333 - DOI: 10.1074/jbc.M110.107730

Maenz DD, Chenu C, Breton S, Berteloot A

pH-dependent heterogeneity of acidic amino acid transport in rabbit jejunal brush border membrane vesicles. J Biol Chem. 1992;267(3):1510-6 - PMID: 1346136

Breton S, Wiederhold T, Marshansky V, Nsumu NN, Ramesh V, Brown D

The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells. J Biol Chem. 2000;275(24):18219-24 - PMID: 10748165 - DOI: 10.1074/jbc.M909857199

Pastor-Soler N, Beaulieu V, Litvin TN, Da Silva N, Chen Y, Brown D, Buck J, Levin LR, Breton S

Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling. J Biol Chem. 2003;278(49):49523-9 - PMID: 14512417 - PMCID: PMC3652382 - DOI: 10.1074/jbc.M309543200

van Balkom BW, van Raak M, Breton S, Pastor-Soler N, Bouley R, van der Sluijs P, Brown D, Deen PM

Hypertonicity is involved in redirecting the aquaporin-2 water channel into the basolateral, instead of the apical, plasma membrane of renal epithelial cells. J Biol Chem. 2002;278(2):1101-7 - PMID: 12374804 - DOI: 10.1074/jbc.M207339200

Li Y, Si R, Feng Y, Chen HH, Zou L, Wang E, Zhang M, Warren HS, Sosnovik DE, Chao W

Myocardial ischemia activates an injurious innate immune signaling via cardiac heat shock protein 60 and Toll-like receptor 4. J Biol Chem. 2011;286(36):31308-19 - PMID: 21775438 - PMCID: PMC3173057 - DOI: 10.1074/jbc.M111.246124

Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ

DRAGON, a bone morphogenetic protein co-receptor. J Biol Chem. 2005;280(14):14122-9 - PMID: 15671031 - DOI: 10.1074/jbc.M410034200

Maranda B, Brown D, Bourgoin S, Casanova JE, Vinay P, Ausiello DA, Marshansky V

Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomes. J Biol Chem. 2001;276(21):18540-50 - PMID: 11278939 - DOI: 10.1074/jbc.M011577200

Hosokawa H, Dip PV, Merkulova M, Bakulina A, Zhuang Z, Khatri A, Jian X, Keating SM, Bueler SA, Rubinstein JL, Randazzo PA, Ausiello DA, Gruber G, Marshansky V

The N-terminus of a-Subunit Isoforms is Involved in Signaling between V-ATPase and Cytohesin-2. J Biol Chem. 2013;288(8):5896-913 - PMID: 23288846 - PMCID: PMC3581410 - DOI: 10.1074/jbc.M112.409169

Feinstein TN, Yui N, Webber MJ, Wehbi VL, Stevenson HP, King JD, Hallows KR, Brown D, Bouley R, Vilardaga JP

Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin. J Biol Chem. 2013;288(39):27849-60 - PMID: 23935101 - PMCID: PMC3784700 - DOI: 10.1074/jbc.M112.445098

Zumbrennen-Bullough K, Wu Q, Core AB, Canali S, Chen W, Theurl I, Meynard D, Babitt JL

MicroRNA-130a is upregulated in mouse liver by iron deficiency and targets the bone morphogenetic protein (BMP) receptor ALK2 to attenuate BMP signaling and hepcidin transcription. J Biol Chem. 2014;289(34):23796-808 - PMID: 25002578 - PMCID: PMC4156078 - DOI: 10.1074/jbc.M114.577387

Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW

ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein. J Biol Chem. 2011;286(47):40443-51 - PMID: 21956108 - PMCID: PMC3220463 - DOI: 10.1074/jbc.M111.280495

Otu HH*, Naxerova K*, Ho K, Can H, Nesbitt N, Libermann TA, Karp SJ

Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns. J Biol Chem. 2007;282(15):11197-204 - PMID: 17227769 - DOI: 10.1074/jbc.M608441200

Rangarajan N, Gordy CL, Askew L, Bevill SM, Elston TC, Errede B, Hurst JH, Kelley JB, Sheetz JB, Suzuki SK, Valentin NH, Young E, Dohlman HG

Systematic analysis of F-box proteins reveals a new branch of the yeast mating pathway. J Biol Chem. 2019;294(40):14717-14731 - PMID: 31399514 - PMCID: PMC6779436 - DOI: 10.1074/jbc.RA119.010063

Chen S, Reynolds F, Yu L, Weissleder R, Josephson L

A screening paradigm for the design of improved polymer-coated superparamagnetic iron oxide nanoparticles J Mater Chem. 2009;19:6387-6392

Zimmer C, Wright SC, Engelhardt RT, Johnson GA, Kramm C, Breakefield XO, Weissleder R

Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface. Exp Neurol. 1997;143(1):61-9 - PMID: 9000446 - DOI: 10.1006/exnr.1996.6350

Enochs WS, Schaffer B, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R

MR imaging of slow axonal transport in vivo. Exp Neurol. 1993;123(2):235-42 - PMID: 8405287 - DOI: 10.1006/exnr.1993.1156

Sinnott JA, Dai W, Liao KP, Shaw SY, Ananthakrishnan AN, Gainer VS, Karlson EW, Churchill S, Szolovits P, Murphy S, Kohane I, Plenge R, Cai T

Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records. Hum Genet. 2014;133(11):1369-82 - PMID: 25062868 - PMCID: PMC4185241 - DOI: 10.1007/s00439-014-1466-9

Bogdanov A Jr, Tung CH, Bredow S, Weissleder R

DNA binding chelates for nonviral gene delivery imaging Gene Ther. 2001;8:515-22 - PMID: 11319618 - DOI: 10.1038/sj.gt.3301410

Schellingerhout D, Rainov NG, Breakefield XO, Weissleder R

Quantitation of HSV mass distribution in a rodent brain tumor model Gene Ther. 2000;7:1648-55 - PMID: 11083473 - DOI: 10.1038/sj.gt.3301272

Shah K, Jacobs A, Breakefield XO, Weissleder R

Molecular imaging of gene therapy for cancer Gene Ther. 2004;11(15):1175-87 - PMID: 15141158 - DOI: 10.1038/sj.gt.3302278

Pai SI, Lin YY, Macaes B, Meneshian A, Hung CF, Wu TC

Prospects of RNA interference therapy for cancer. Gene Ther. 2006;13(6):464-77 - PMID: 16341059 - DOI: 10.1038/sj.gt.3302694

Wu A, Zeng Q, Kang TH, Peng S, Roosinovich E, Pai SI, Hung CF

Innovative DNA vaccine for human papillomavirus (HPV)-associated head and neck cancer. Gene Ther. 2010;18(3):304-12 - PMID: 20981112 - PMCID: PMC3032008 - DOI: 10.1038/gt.2010.151

Kang TH, Chung JY, Monie A, Pai SI, Hung CF, Wu TC

Enhancing DNA vaccine potency by co-administration of xenogenic MHC class-I DNA. Gene Ther. 2009;17(4):531-40 - PMID: 19940864 - PMCID: PMC2851845 - DOI: 10.1038/gt.2009.152

Kim JW, Hung CF, Juang J, He L, Kim TW, Armstrong DK, Pai SI, Chen PJ, Lin CT, Boyd DA, Wu TC

Comparison of HPV DNA vaccines employing intracellular targeting strategies. Gene Ther. 2004;11(12):1011-8 - PMID: 14985791 - DOI: 10.1038/sj.gt.3302252

Wang TL, Ling M, Shih IM, Pham T, Pai SI, Lu Z, Kurman RJ, Pardoll DM, Wu TC

Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity. Gene Ther. 2000;7(9):726-33 - PMID: 10822298 - DOI: 10.1038/sj.gt.3301160

Filz von Reiterdank I, Mojoudi M, Bento R, Taggart MS, Dinicu AT, Wojtkiewicz G, Coert JH, Mink van der Molen AB, Weissleder R, Parekkadan B, Uygun K

Ex vivo machine perfusion as a platform for lentiviral gene delivery in rat livers. Gene Ther. 2025;32(4):421-429 - PMID: 40263629 - DOI: 10.1038/s41434-025-00536-7

Moskowitz MA

Rethinking migraine with aura: Why cortical spreading depolarization (depression), not aura, causes headaches. Cephalalgia. 2025;45(9):3331024251370629 - PMID: 40891631 - DOI: 10.1177/03331024251370629

Merkulova M, Bakulina A, Thaker YR, Gruber G, Marshansky V

Specific motifs of the V-ATPase a2-subunit isoform interact with catalytic and regulatory domains of ARNO. Biochim Biophys Acta. 2010;1797(8):1398-1409 - PMID: 20153292 - DOI: 10.1016/j.bbabio.2010.02.009

Moore A, Basilion JP, Chiocca EA, Weissleder R

Measuring transferrin receptor gene expression by NMR imaging. Biochim Biophys Acta. 1998;1402(3):239-49 - PMID: 9606982 - DOI: 10.1016/s0167-4889(98)00002-0

Bogdanov A, Simonova M, Weissleder R

Design of metal-binding green fluorescent protein variants. Biochim Biophys Acta. 1998;1397(1):56-64 - PMID: 9545533 - DOI: 10.1016/s0167-4781(97)00221-2

Bogdanov AA, Martin C, Weissleder R, Brady TJ

Trapping of dextran-coated colloids in liposomes by transient binding to aminophospholipid: preparation of ferrosomes. Biochim Biophys Acta. 1994;1193(1):212-8 - PMID: 7518693 - DOI: 10.1016/0005-2736(94)90350-6

Da Silva N, Pietrement C, Brown D, Breton S

Segmental and cellular expression of aquaporins in the male excurrent duct. Biochim Biophys Acta. 2006;1758(8):1025-33 - PMID: 16935257 - DOI: 10.1016/j.bbamem.2006.06.026

Marshansky V, Rubinstein JL, Grüber G

Eukaryotic V-ATPase: Novel Structural Findings and Functional Insights. Biochim Biophys Acta. 2014;1837(6):857-879 - PMID: 24508215 - DOI: 10.1016/j.bbabio.2014.01.018

Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R

SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration. J Leukocyte biol. 2006;81(3):748-56 - PMID: 17178915 - DOI: 10.1189/jlb.1105664

Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF

A colorimetric high throughput screen for the detection of heme crystallization inhibitors. Antimicrob Agents Chemother. 2009;53(6):2564-8 - PMID: 19307367 - PMCID: PMC2687197 - DOI: 10.1128/AAC.01466-08

Weissleder R, Poss K, Wilkinson R, Zhou C, Bogdanov A

Quantitation of slow drug release from an implantable and degradable gentamicin conjugate by in vivo magnetic resonance imaging. Antimicrob Agents Chemother. 1995;39(4):839-45 - PMID: 7785981 - PMCID: PMC162639 - DOI: 10.1128/aac.39.4.839

Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman BI, Angulo-Barturen I, Jimenez-Diaz MB, Magan N, Gomez V, Ferrer S, Santos Marti

Aminoindoles: a Novel Scaffold with Potent Activity against Plasmodium falciparum. Antimicrob Agents Chemother. 2011;55(6):2612-22 - PMID: 21422215 - PMCID: PMC3101419 - DOI: 10.1128/AAC.01714-10

Liston SD, Whitesell L, McLellan CA, Mazitschek R, Petraitis V, Petraitiene R, Kavaliauskas P, Walsh TJ, Cowen LE

Antifungal activity of gepinacin-scaffold GPI anchor biosynthesis inhibitors with improved metabolic stability. Antimicrob Agents Chemother. 2020;64(10):ePub - PMID: 32661007 - PMCID: PMC7508603 - DOI: 10.1128/AAC.00899-20

Păunescu TG, Shum WW, Huynh C, Lechner L, Goetze B, Brown D, Breton S

High-resolution helium ion microscopy of epididymal epithelial cells and their interaction with spermatozoa. Mol Hum Reprod. 2014;20(10):929-37 - PMID: 25015675 - PMCID: PMC4172170 - DOI: 10.1093/molehr/gau052

Shi S, Hoogaars WM, de Gorter DJ, van Heiningen SH, Lin HY, Hong CC, Kemaladewi DU, Aartsma-Rus A, Ten Dijke P, 't Hoen PA

BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model. Neurobiol Dis. 2010;41(2):353-60 - PMID: 20940052 - PMCID: PMC3674857 - DOI: 10.1016/j.nbd.2010.10.003

Hughes BN, Jorgensen KA, Cummings S, Morah D, Krause K, Rauh-Hain JA, Herzog TJ

Systematic mapping review of guidelines for BRCA1/2 genetic testing globally: investigating geographic and regional disparities in health equity for women and families at risk for hereditary ovarian cancer. Int J Gynecol Cancer. 2023;33(2):250-256 - PMID: 36368709 - PMCID: PMC12234120 - DOI: 10.1136/ijgc-2022-003913

Setoguchi S, Higgins JM, Mogun H, Mootha VK, Avorn J

Propranolol and the risk of hospitalized myopathy: Translating chemical genomics findings into population-level hypotheses. Am Heart J. 2010;159(3):428-433 - PMID: 20211305 - DOI: 10.1016/j.ahj.2009.12.008

Larkin M, Nathan DM, Bebu I, Krause-Steinrauf H, Herman WH, Higgins JM, Tiktin M, Cohen RM, Lund C, Bergenstal RM, Johnson M, Arends V, Research Group G

Rationale and Design for a GRADE Substudy of Continuous Glucose Monitoring. Diabetes Technol Ther. 2019;21(12):682-690 - PMID: 31393176 - PMCID: PMC7207016 - DOI: 10.1089/dia.2019.0202

Huang X, Im H, Lee D, Kim H, Choi Y

Ferrocene Functionalized Single-Walled Carbon Nanotube Bundles. Hybrid Interdigitated Construction Film for l-Glutamate Detection J Phys Chem C. 2007;111(3):1200-1206

Cortez-Retamozo V, Etzrodt M, Pittet MJ

Regulation of Macrophage and Dendritic Cell Responses by Their Lineage Precursors. J Innate Immunity. 2012;4(5-6):411-23 - PMID: 22433183 - PMCID: PMC3498093 - DOI: 10.1159/000335733

Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE

Noninvasive imaging of apoptosis in cardiovascular disease. Heart Fail Rev. 2008;13(2)::163-173 - PMID: 18074226 - PMCID: PMC2597223 - DOI: 10.1007/s10741-007-9068-4

Kilic T, Weissleder R, Lee H

Molecular and immunological diagnostic tests of COVID-19 – current status and challenges iScience. 2020;23(8):101406 - PMID: 32771976 - PMCID: PMC7381402 - DOI: 10.1016/j.isci.2020.101406

Poli V, Pui-Yan Ma V, Di Gioia M, Broggi A, Benamar M, Chen Q, Mazitschek R, Haggarty SJ, Chatila TA, Karp JM, Zanoni I

Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation. iScience. 2021;24(11):103256 - PMID: 34761180 - PMCID: PMC8567386 - DOI: 10.1016/j.isci.2021.103256

Higgins JM, Eddington DT, Bhatia SN, Mahadevan L

Statistical dynamics of flowing red blood cells by morphological image processing. PLoS Comput Biol. 2009;5(2):e1000288 - PMID: 19214200 - PMCID: PMC2631282 - DOI: 10.1371/journal.pcbi.1000288

Malka R, Delgado FF, Manalis SR, Higgins JM

In Vivo Volume and Hemoglobin Dynamics of Human Red Blood Cells. PLoS Comput Biol. 2014;10(10):e1003839 - PMID: 25299941 - PMCID: PMC4191880 - DOI: 10.1371/journal.pcbi.1003839

Miller M, Hafner M, Sontag E, Davidsohn N, Subramanian S, Purnick PE, Lauffenburger D, Weiss R

Modular design of artificial tissue homeostasis: robust control through synthetic cellular heterogeneity. PLoS Comput Biol. 2012;8(7):e1002579 - PMID: 22829755 - PMCID: PMC3400602 - DOI: 10.1371/journal.pcbi.1002579

Diamant N, Reinertsen E, Song S, Aguirre AD, Stultz CM, Batra P

Patient contrastive learning: A performant, expressive, and practical approach to electrocardiogram modeling. PLoS Comput Biol. 2022;18(2):e1009862 - PMID: 35157695 - PMCID: PMC8880931 - DOI: 10.1371/journal.pcbi.1009862

Tung CH, Quinti L, Jaffer F, Weissleder R

A Branched Fluorescent Peptide Probe for Imaging of Activated Platelets Mol Pharmacol. 2005;2:92-95 - PMID: 15804182 - DOI: 10.1021/mp0499048

Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV

8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells. Mol Pharmacol. 2007;72(5):1137-45 - PMID: 17675586 - DOI: 10.1124/mol.107.038117

Kelly K*, Shaw SY*, Nahrendorf M, Kristoff K, Aikawa E, Schreiber SL, Clemons PA, Weissleder R.

Unbiased discovery of in vivo imaging probes through in vitro profiling of nanoparticle libraries. Integr Biol (Camb). 2009;1(4):311-317 - PMID: 20023731 - PMCID: PMC2748356 - DOI: 10.1039/b821775k

Taqueti VR, Jaffer FA

High-resolution molecular imaging via intravital microscopy: illuminating vascular biology in vivo. Integr Biol (Camb). 2013;5(2):278-90 - PMID: 23135362 - PMCID: PMC3558556 - DOI: 10.1039/c2ib20194a

Miller MA, Barkal L, Jeng K, Herrlich A, Moss M, Griffith LG, Lauffenburger DA

Proteolytic Activity Matrix Analysis (PrAMA) for simultaneous determination of multiple protease activities. Integr Biol (Camb). 2010;3(4):422-38 - PMID: 21180771 - PMCID: PMC3173501 - DOI: 10.1039/c0ib00083c

Jalali Motlagh N, Wang C, Kuellenberg EG, Wojtkiewicz GR, Schmidt S, Chen JW

D-Mannose Slows Glioma Growth by Modulating Myeloperoxidase Activity. Cancers (Basel). 2021;13(24):ePub - PMID: 34944979 - PMCID: PMC8699108 - DOI: 10.3390/cancers13246360

Hsia T, Small JL, Yekula A, Batool SM, Escobedo AK, Ekanayake E, You DG, Lee H, Carter BS, Balaj L

Systematic Review of Photodynamic Therapy in Gliomas. Cancers (Basel). 2023;15(15):ePub - PMID: 37568734 - PMCID: PMC10417382 - DOI: 10.3390/cancers15153918

Rami A, Zhong C, Muniz M, Xie W, Khorasanchi A, Gallagher J, Mohammadi S, Fein D, Voter AF, Stoltenberg H, Gopalakrishan D, Yang Y, Ng TSC, Gafita A, Childs DS, Jacene H, Ravi P

Race and Outcomes to [177Lu]Lu-PSMA-617 in Advanced Prostate Cancer. Cancers (Basel). 2025;17(12):ePub - PMID: 40563610 - PMCID: PMC12191161 - DOI: 10.3390/cancers17121960

Ruan YC, Shum WW, Belleannée C, Da Silva N, Breton S

ATP secretion in the male reproductive tract: essential role of CFTR. J Physiol. 2012;590(Pt 17):4209-22 - PMID: 22711960 - PMCID: PMC3473280 - DOI: 10.1113/jphysiol.2012.230581

Cheung PW, Terlouw A, Janssen SA, Brown D, Bouley R

Inhibition of non-receptor tyrosine kinase Src induces phosphoserine 256-independent aquaporin-2 membrane accumulation. J Physiol. 2018;597(6):1627-1642 - PMID: 30488437 - PMCID: PMC6418769 - DOI: 10.1113/JP277024

Battistone MA, Merkulova M, Park YJ, Peralta MA, Gombar F, Brown D, Breton S

Unraveling purinergic regulation in the epididymis: Activation of V-ATPase-dependent acidification by luminal ATP and adenosine. J Physiol. 2019;597(7):1957-1973 - PMID: 30746715 - PMCID: PMC6441927 - DOI: 10.1113/JP277565

Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model. ACS Chem Biol. 2009;4(7):527-33 - PMID: 19572548 - PMCID: PMC2745594 - DOI: 10.1021/cb900084v

McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S

Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity. ACS Chem Biol. 2012;7(9):1520-8 - PMID: 22724584 - DOI: 10.1021/cb300235m

Shaw SY, Tran K, Castoreno AB, Peloquin JM, Lassen KG, Khor B, Aldrich LN, Tan PH, Graham DB, Kuballa P, Goel G, Daly MJ, Shamji AF, Schreiber SL, Xavier RJ

Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules. ACS Chem Biol. 2013;8(12):2724-33 - PMID: 24168452 - PMCID: PMC3951132 - DOI: 10.1021/cb400352d

McLellan CA, Whitesell L, King OD, Lancaster AK, Mazitschek R, Lindquist S

Correction to Inhibiting GPI Anchor Biosynthesis in Fungi Stresses the Endoplasmic Reticulum and Enhances Immunogenicity. ACS Chem Biol. 2012;9(4):1061 - PMID: 22724584 - DOI: 10.1021/cb300235m

Iaconelli J, Huang JH, Berkovitch SS, Chattopadhyay S, Mazitschek R, Schreiber SL, Haggarty SJ, Karmacharya R

HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells. ACS Chem Biol. 2015;10(3):883-90 - PMID: 25546293 - PMCID: PMC4372110 - DOI: 10.1021/cb500838r

Iaconelli J, Lalonde J, Watmuff B, Liu B, Mazitschek R, Haggarty SJ, Karmacharya R

Lysine Deacetylation by HDAC6 Regulates the Kinase Activity of AKT in Human Neural Progenitor Cells. ACS Chem Biol. 2017;12(8):2139-2148 - PMID: 28628306 - PMCID: PMC6747705 - DOI: 10.1021/acschembio.6b01014

Koch PD, Ahmed MS, Kohler RH, Li R, Weissleder R

Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand. ACS Chem Biol. 2019;15(1):151-157 - PMID: 31809013 - PMCID: PMC7808335 - DOI: 10.1021/acschembio.9b00724

Badr CE, da Hora CC, Kirov AB, Tabet E, Amante R, Maksoud S, Nibbs AE, Fitzsimons E, Boukhali M, Chen JW, Chiu NHL, Nakano I, Haas W, Mazitschek R, Tannous BA

Obtusaquinone is a cysteine modifying compound that targets Keap1 for degradation. ACS Chem Biol. 2020;15(6):1445-1454 - PMID: 32338864 - PMCID: PMC7995447 - DOI: 10.1021/acschembio.0c00104

Pittet MJ, Nahrendorf M, Swirski FK

The journey from stem cell to macrophage. Ann N Y Acad Sci. 2014;1319(1):1-18 - PMID: 24673186 - PMCID: PMC4074243 - DOI: 10.1111/nyas.12393

Bhaumik J, Weissleder R, McCarthy JR

Synthesis and Photophysical Properties of Sulfonamidophenyl Porphyrins as Models for Activatable Photosensitizers. J Org Chem. 2009;74(16):5894-901 - PMID: 19610602 - PMCID: PMC2888918 - DOI: 10.1021/jo900832y

Brueckner C, Ogikubo J, McCarthy JR, Akhigbe J, Hyland MA, Daddario P, Worlinsky JL, Zeller M, Engle JT, Ziegler CJ, Ranaghan MJ, Sandberg MN, Birge RR

meso-Arylporpholactones and their Reduction Products. J Org Chem. 2012;77(15):6480-94 - PMID: 22734444 - PMCID: PMC3411881 - DOI: 10.1021/jo300963m

Srinivasulu V, Srikanth G, Khanfar MA, Abu-Yousef IA, Majdalawieh AF, Mazitschek R, Setty SC, Sebastian A, Al-Tel TH

Stereodivergent Complexity-to-Diversity Strategy en Route to the Synthesis of Nature-Inspired Skeleta. J Org Chem. 2022;87(2):1377-1397 - PMID: 35014258 - DOI: 10.1021/acs.joc.1c02698

Bogdanov AA, Lin CP, Kang HW

Optical imaging of the adoptive transfer of human endothelial cells in mice using anti-human CD31 monoclonal antibody. Pharmacol Res. 2007;24:1186-92 - PMID: 17373582 - PMCID: PMC2795329 - DOI: 10.1007/s11095-006-9219-7

Roedl JB, Harisinghani MG, Colen RR, Fischman AJ, Blake MA, Mathisen DJ, Mueller PR

Assessment of treatment response and recurrence in esophageal carcinoma based on tumor length and standardized uptake value on positron emission tomography-computed tomography. Ann Thorac Surg. 2008;86:1131-8 - PMID: 18805147 - DOI: 10.1016/j.athoracsur.2008.05.019

Kim KM, Cambria RP, Isselbacher EM, Baker JN, LaMuraglia GM, Stone JR, MacGillivray TE

Contemporary Surgical Approaches and Outcomes in Adults With Kommerell Diverticulum. Ann Thorac Surg. 2014;98(4):1347-1354 - PMID: 25134861 - DOI: 10.1016/j.athoracsur.2014.05.045

Heng E, Stone JR, Kim JB, Lee H, MacGillivray TE, Sundt TM

Comparative Histology of Aortic Dilatation Associated With Bileaflet Versus Trileaflet Aortic Valves. Ann Thorac Surg. 2015;100(6):2095-2101 - PMID: 26338050 - DOI: 10.1016/j.athoracsur.2015.05.105

Raghu VK, Moonsamy P, Sundt TM, Ong CS, Singh S, Cheng A, Hou M, Denning L, Gleason TG, Aguirre AD, Lu MT

Deep learning to predict mortality after cardiothoracic surgery using preoperative chest radiographs. Ann Thorac Surg. 2022;115(1):257-264 - PMID: 35609650 - PMCID: PMC11373441 - DOI: 10.1016/j.athoracsur.2022.04.056

Fagbami L, Deik AA, Herman JD, Singh K, Santos SA, Bopp S, Lukens AK, Clish CB, Wirth DF, Mazitschek R

The adaptive proline response in P. falciparum is independent of PfeIK1 and eIF2α signaling. ACS Infect Dis. 2019;5(4):515-520 - PMID: 30773881 - PMCID: PMC6747701 - DOI: 10.1021/acsinfecdis.8b00363

Michot C, Le Goff C, Mahaut C, Afenjar A, Brooks AS, Campeau PM, Destree A, Di Rocco M, Donnai D, Hennekam R, Heron D, Jacquemont S, Kannu P, Lin AE, Manouvrier-Hanu S, Mansour S, Marlin S, McGowan R, Murphy H, Raas-Rothschild A, Rio M, Simon M, Stolte-Dijkstra I, Stone JR, Sznajer Y, Tolmie J, Touraine R, van den Ende J, Van der Aa N, van Essen T, Verloes A, Munnich A, Cormier-Daire V

Myhre and LAPS syndromes: clinical and molecular review of 32 patients. Eur J Hum Genet. 2014;22(11):1272-7 - PMID: 24424121 - PMCID: PMC4200423 - DOI: 10.1038/ejhg.2013.288

Chen WT, Mahmood U, Weissleder R, Tung CH

Arthritis imaging using a near-infrared fluorescence folate-targeted probe Arthritis Res Ther. 2005;7:R310-R317 - PMID: 15743478 - PMCID: PMC1065321 - DOI: 10.1186/ar1483

Rao SM, Auger JL, Gaillard P, Weissleder R, Wada E, Torres R, Kojima M, Benoist C, Mathis D, Binstadt BA

The neuropeptide neuromedin U promotes autoantibody-mediated arthritis. Arthritis Res Ther. 2012;14(1):R29 - PMID: 22314006 - PMCID: PMC3392824 - DOI: 10.1186/ar3732

Lee S, Vinegoni C, Sebas M, Weissleder R

Automated motion artifact removal for intravital microscopy, without a priori information. Sci Rep. 2014;4:4507 - PMID: 24676021 - PMCID: PMC3968488 - DOI: 10.1038/srep04507

Turetsky A, Kim E, Kohler RH, Miller MA, Weissleder R

Single cell imaging of Bruton's tyrosine kinase using an irreversible inhibitor. Sci Rep. 2014;4:4782 - PMID: 24759210 - PMCID: PMC3998017 - DOI: 10.1038/srep04782

Yang KS, Kohler RH, Landon M, Giedt R, Weissleder R

Single cell resolution in vivo imaging of DNA damage following PARP inhibition Sci Rep. 2015;5:10129 - PMID: 25984718 - PMCID: PMC4434991 - DOI: 10.1038/srep10129

Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, Hanna RN, Wu R, Swirski FK, Geissmann F, Hedrick CC

The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus. Sci Rep. 2015;5:10055 - PMID: 26091486 - PMCID: PMC4473761 - DOI: 10.1038/srep10055

Clardy SM, James F. Mohan JF, Vinegoni C, Keliher EJ, Iwamoto Y, Benoist C, Mathis D, Weissleder R

Rapid, high efficiency isolation of pancreatic ß-cells Sci Rep. 2015;5:13681 - PMID: 26330153 - PMCID: PMC4557033 - DOI: 10.1038/srep13681

Merkulova M, Păunescu TG, Azroyan A, Marshansky V, Breton S, Brown D

Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation. Sci Rep. 2015;5:14827 - PMID: 26442671 - PMCID: PMC4595830 - DOI: 10.1038/srep14827

Kuijten MM, Hannah Degeling M, Chen JW, Wojtkiewicz G, Waterman P, Weissleder R, Azzi J, Nicolay K, Tannous BA

Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging. Sci Rep. 2015;5:17220 - PMID: 26610702 - PMCID: PMC4661695 - DOI: 10.1038/srep17220

Wu JW, Turcotte R, Alt C, Runnels JM, Tsao H, Lin CP

Defining Clonal Color in Fluorescent Multi-Clonal Tracking Sci Rep. 2016;6:24303 - PMID: 27073117 - PMCID: PMC4829845 - DOI: 10.1038/srep24303

Song J, Leon Swisher C, Im H, Jeong S, Pathania D, Iwamoto Y, Pivovarov M, Weissleder R, Lee H

Sparsity-Based Pixel Super Resolution for Lens-Free Digital In-line Holography. Sci Rep. 2016;6:24681 - PMID: 27098438 - PMCID: PMC4838824 - DOI: 10.1038/srep24681

Yang Z, Concannon J, Ng KS, Seyb K, Mortensen LJ, Ranganath S, Gu F, Levy O, Tong Z, Martyn K, Zhao W, Lin CP, Glicksman MA, Karp JM

Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation. Sci Rep. 2016;6:30263 - PMID: 27457881 - PMCID: PMC4960598 - DOI: 10.1038/srep30263

Park KS, Chung HJ, Khanam F, Lee H, Rashu R, Bhuiyan MT, Berger A, Harris JB, Calderwood SB, Ryan ET, Qadri F, Weissleder R, Charles RC

A magneto-DNA nanoparticle system for the rapid and sensitive diagnosis of enteric fever. Sci Rep. 2016;6:32878 - PMID: 27605393 - PMCID: PMC5015101 - DOI: 10.1038/srep32878

Giedt RJ, Fumene Feruglio P, Pathania D, Yang KS, Kilcoyne A, Vinegoni C, Mitchison TJ, Weissleder R

Computational imaging reveals mitochondrial morphology as a biomarker of cancer phenotype and drug response Sci Rep. 2016;6:32985 - PMID: 27609668 - PMCID: PMC5017129 - DOI: 10.1038/srep32985

Beam AL, Kartoun U, Pai JK, Chatterjee AK, Fitzgerald TP, Shaw SY, Kohane IS

Predictive Modeling of Physician-Patient Dynamics That Influence Sleep Medication Prescriptions and Clinical Decision-Making. Sci Rep. 2017;7:42282 - PMID: 28181568 - PMCID: PMC5299453 - DOI: 10.1038/srep42282

Miller MA, Moss ML, Powell G, Petrovich R, Edwards L, Meyer AS, Griffith LG, Lauffenburger DA

Targeting autocrine HB-EGF signaling with specific ADAM12 inhibition using recombinant ADAM12 prodomain. Sci Rep. 2015;5:15150 - PMID: 26477568 - PMCID: PMC4609913 - DOI: 10.1038/srep15150

Turcotte R, Alt C, Runnels JM, Ito K, Wu JW, Zaher W, Mortensen LJ, Silberstein L, Côté DC, Kung AL, Ito K, Lin CP

Image-guided transplantation of single cells in the bone marrow of live animals. Sci Rep. 2017;7(1):3875 - PMID: 28634334 - PMCID: PMC5478633 - DOI: 10.1038/s41598-017-02896-6

Nairz M, Haschka D, Dichtl S, Sonnweber T, Schroll A, Aßhoff M, Mindur JE, Moser PL, Wolf D, Swirski FK, Theurl I, Cerami A, Brines M, Weiss G

Cibinetide dampens innate immune cell functions thus ameliorating the course of experimental colitis. Sci Rep. 2017;7(1):13012 - PMID: 29026145 - PMCID: PMC5638901 - DOI: 10.1038/s41598-017-13046-3

Brannen A, Eggert M, Nahrendorf M, Arnold R, Panizzi P

Correlation of 360-degree Surface Mapping In Vivo Bioluminescence with Multi-Spectral Optoacoustic Tomography in Human Xenograft Tumor Models. Sci Rep. 2018;8(1):3321 - PMID: 29463820 - PMCID: PMC5820276 - DOI: 10.1038/s41598-018-21668-4

Yeh SA, Wilk K, Lin CP, Intini G

In Vivo 3D Histomorphometry Quantifies Bone Apposition and Skeletal Progenitor Cell Differentiation. Sci Rep. 2018;8(1):5580 - PMID: 29615817 - PMCID: PMC5882859 - DOI: 10.1038/s41598-018-23785-6

Aganj I, Harisinghani MG, Weissleder R, Fischl B

Unsupervised medical image segmentation based on the local center of mass Sci Rep. 2018;8:13012 - PMID: 30158534 - PMCID: PMC6115387 - DOI: 10.1038/s41598-018-31333-5

Vasaturo M, Cotugno R, Fiengo L, Vinegoni C, Dal Piaz F, De Tommasi N

The anti-tumor diterpene oridonin is a direct inhibitor of Nucleolin in cancer cells. Sci Rep. 2018;8(1):16735 - PMID: 30425290 - PMCID: PMC6233161 - DOI: 10.1038/s41598-018-35088-x

Kim SJ*, Wang C*, Zhao B, Im H, Min J, Choi HJ, Tadros J, Choi NR, Castro CM, Weissleder R, Lee H, Lee K

Deep transfer learning-based hologram classification for molecular diagnostics. Sci Rep. 2018;8(1):17003 - PMID: 30451953 - PMCID: PMC6242900 - DOI: 10.1038/s41598-018-35274-x

Carvajal G, Brukman NG, Weigel Muñoz M, Battistone MA, Guazzone VA, Ikawa M, Haruhiko M, Lustig L, Breton S, Cuasnicu PS

Impaired male fertility and abnormal epididymal epithelium differentiation in mice lacking CRISP1 and CRISP4. Sci Rep. 2018;8(1):17531 - PMID: 30510210 - PMCID: PMC6277452 - DOI: 10.1038/s41598-018-35719-3

Tan X, Patil R, Bartosik P, Runnels JM, Lin CP, Niedre M

In Vivo Flow Cytometry of Extremely Rare Circulating Cells. Sci Rep. 2019;9(1):3366 - PMID: 30833671 - PMCID: PMC6399281 - DOI: 10.1038/s41598-019-40143-2

Zaborowski MP, Cheah PS, Zhang X, Bushko I, Lee K, Sammarco A, Zappulli V, Maas SLN, Allen RM, Rumde P, György B, Aufiero M, Schweiger MW, Lai CP, Weissleder R, Lee H, Vickers KC, Tannous BA, Breakefield XO

Membrane-bound Gaussia luciferase as a tool to track shedding of membrane proteins from the surface of extracellular vesicles. Sci Rep. 2019;9(1):17387 - PMID: 31758005 - PMCID: PMC6874653 - DOI: 10.1038/s41598-019-53554-y

Figueiredo JL, Santa-Cruz F, Lima-Filho JL, Hilgendorf I, Aikawa M, Pittet MJ, Nahrendorf M, Weissleder R, Swirski FK, Robbins CS

A durable murine model of spleen transplantation with arterial and venous anastomoses. Sci Rep. 2020;10(1):3979 - PMID: 32132617 - PMCID: PMC7055260 - DOI: 10.1038/s41598-020-60983-7

Vinegoni C, Fumene Feruglio P, Courties G, Schmidt S, Hulsmans M, Lee S, Wang R, Sosnovik D, Nahrendorf M, Weissleder R

Fluorescence microscopy tensor imaging representations for large-scale dataset analysis. Sci Rep. 2020;10(1):5632 - PMID: 32221334 - PMCID: PMC7101442 - DOI: 10.1038/s41598-020-62233-2

Hou J, Lin CP, Intini G

Activation of creER recombinase in the mouse calvaria induces local recombination without effects on distant skeletal segments. Sci Rep. 2021;11(1):8214 - PMID: 33859263 - PMCID: PMC8050205 - DOI: 10.1038/s41598-021-87611-2

Yang KS, O'Shea A, Zelga P, Liss AS, Del Castillo CF, Weissleder R

Extracellular vesicle analysis of plasma allows differential diagnosis of atypical pancreatic serous cystadenoma. Sci Rep. 2023;13(1):10969 - PMID: 37414831 - PMCID: PMC10325992 - DOI: 10.1038/s41598-023-37966-5

Bagramyan A, Lin CP

Miniaturized microscope for non-invasive imaging of leukocyte-endothelial interaction in human microcirculation. Sci Rep. 2023;13(1):17881 - PMID: 37857684 - PMCID: PMC10587353 - DOI: 10.1038/s41598-023-45018-1

Rosenthal ZC, Fass DM, Payne NC, She A, Patnaik D, Hennig KM, Tesla R, Werthmann GC, Guhl C, Reis SA, Wang X, Chen Y, Placzek M, Williams NS, Hooker J, Herz J, Mazitschek R, Haggarty SJ

Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia. Sci Rep. 2024;14(1):9064 - PMID: 38643236 - PMCID: PMC11032351 - DOI: 10.1038/s41598-024-59110-7

Landeros C, Oh J, Weissleder R, Lee H

Deep learning pipeline for automated cell profiling from cyclic imaging Sci Rep. 2024;14(1):23600 - PMID: 39384907 - PMCID: PMC11464789 - DOI: 10.1038/s41598-024-74597-w

Bozhko D, Osborn EA, Rosenthal A, Verjans JW, Hara T, Kellnberger S, Wissmeyer G, Ovsepian SV, McCarthy JR, Mauskapf A, Stein AF, Jaffer FA, Ntziachristos V

Quantitative intravascular biological fluorescence-ultrasound imaging of coronary and peripheral arteries in vivo. Eur Heart J Cardiovasc Imaging. 2017;18(11):1253-1261 - PMID: 28031233 - PMCID: PMC5837649 - DOI: 10.1093/ehjci/jew222

Bhatia RS, Kumar V, Picard MH, Weiner RB

Comparison of the 2008 and 2011 appropriate use criteria for stress echocardiography. J Am Soc Echocardiogr. 2013;26(4):339-43 - PMID: 23313389 - DOI: 10.1016/j.echo.2012.12.001

Pang Y, Tsigkou O, Spencer JA, Lin CP, Neville C, Grottkau B

Analyzing Structure and Function of Vascularization in Engineered Bone Tissue by Video-rate Intravital Microscopy and 3D Image Processing. Tissue Eng Part C Methods. 2015;21(10):1025-1031 - PMID: 25962617 - PMCID: PMC4593976 - DOI: 10.1089/ten.TEC.2015.0091

Liu J, Wang W, Liu M, Su L, Zhou H, Xia Y, Ran J, Lin HY, Yang B

Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway. Cell Signal. 2016;28(12):1842-1851 - PMID: 27575743 - DOI: 10.1016/j.cellsig.2016.08.015

Abou Haidar E, Prabhakar S, Geffrey AL, Mahamdeh M, Tomeh T, Breyne K, Roumieh E, Gurevich M, Soberman RJ, Wojtkiewicz GR, Chen JW, Han JS, Stemmer-Rachamimov A, Breakefield XO

AAV hamartin gene therapy in a stochastic, cerebral mouse model of tuberous sclerosis type 1. Mol Ther Methods Clin Dev. 2025;33(3):101556 - PMID: 40932991 - PMCID: PMC12419009 - DOI: 10.1016/j.omtm.2025.101556

Zhao WN, Ghosh B, Tyler M, Lalonde J, Joseph NF, Kosaric N, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ

Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory. ACS Chem Neurosci. 2018;9(9):2262-2273 - PMID: 29932631 - DOI: 10.1021/acschemneuro.8b00116

Graves EE, Weissleder R, Ntziachristos V

Fluorescence molecular imaging of small animal tumor models. Curr Mol Med. 2004;4(4):419-30 - PMID: 15354872 - DOI: 10.2174/1566524043360555

Russo LM, Brown D, Lin HY

The soluble transforming growth factor-beta receptor: Advantages and applications. Int J Biochem Cell B. 2008;41(3):472-6 - PMID: 18339576 - DOI: 10.1016/j.biocel.2008.01.026

Robbins C, Dawe D, Goncharova S, Pouladi M, Drannik A, Swirski F, Cox G, Stampfli M

Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness. Am J Respir Cell Mol Biol. 2004;30(2):202-11 - PMID: 12920055 - DOI: 10.1165/rcmb.2003-0259OC

Pouladi M, Robbins C, Swirski F, Cundall M, McKenzie A, Jordana M, Shapiro S, Stampfli M

Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice. Am J Respir Cell Mol Biol. 2004;30(1):84-90 - PMID: 12842850 - DOI: 10.1165/rcmb.2003-0051OC

Gajewska B, Swirski F, Alvarez D, Ritz S, Goncharova S, Cundall M, Snider D, Coyle A, Gutierrez-Ramos J, Stampfli M, Jordana M

Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation. Am J Respir Cell Mol Biol. 2001;25:326-34 - PMID: 11588010 - DOI: 10.1165/ajrcmb.25.3.4482

Kim JK, Vinarsky V, Wain JC, Zhao R, Jung K, Choi J, Lam A, Pardo-Saganta A, Breton S, Rajagopal J, Yun SH

In vivo imaging of tracheal epithelial cells in mice during airway regeneration. Am J Respir Cell Mol Biol. 2012;47(6):864-8 - PMID: 22984086 - PMCID: PMC3547097 - DOI: 10.1165/rcmb.2012-0164OC

Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Groves Kuhnle CE, Tang W, Barker DD, Mazitschek R, Schreiber SL, Tsai LH, Haggarty SJ

Crebinostat: A Novel cognitive enhancer that inhibits Histone Deacetylase activity and Modulates Chromatin-mediated Neuroplasticity. Neuropharmacology. 2012;64(1):81-96 - PMID: 22771460 - PMCID: PMC3447535 - DOI: 10.1016/j.neuropharm.2012.06.043

Nairz M, Theurl I, Swirski FK, Weiss G

"Pumping iron" - how macrophages handle iron at the systemic, microenvironmental, and cellular levels. Pflugers Arch. 2017;469(3-4):397-418 - PMID: 28251312 - PMCID: PMC5362662 - DOI: 10.1007/s00424-017-1944-8

Sheth RA, Upadhyay R, Stangenberg L, Sheth R, Weissleder R, Mahmood U

Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model. Gynecol Oncol. 2009;112(3):616-22 - PMID: 19135233 - PMCID: PMC2664404 - DOI: 10.1016/j.ygyno.2008.11.018

Oza AM, Tinker AV, Oaknin A, Shapira-Frommer R, McNeish IA, Swisher EM, Ray-Coquard I, Bell-McGuinn K, Coleman RL, O'Malley DM, Leary A, Chen LM, Provencher D, Ma L, Brenton JD, Konecny GE, Castro CM, Giordano H, Maloney L, Goble S, Lin KK, Sun J, Raponi M, Rolfe L, Kristeleit RS

Antitumor activity and safety of the PARP inhibitor rucaparib in patients with high-grade ovarian carcinoma and a germline or somatic BRCA1 or BRCA2 mutation: Integrated analysis of data from Study 10 and ARIEL2. Gynecol Oncol. 2017;147(2):267-275 - PMID: 28882436 - DOI: 10.1016/j.ygyno.2017.08.022

Krasner CN, Castro C, Penson RT, Roche M, Matulonis UA, Morgan MA, Drescher C, Armstrong DK, Wolfe JK, Lee H, Supko JG, Seiden M, Birrer MJ, Dizon DS

Final report on serial phase II trials of all-intraperitoneal chemotherapy with or without bevacizumab for women with newly diagnosed, optimally cytoreduced carcinoma of Müllerian origin. Gynecol Oncol. 2019;153(2):223-229 - PMID: 30765148 - DOI: 10.1016/j.ygyno.2019.02.004

O'Malley DM, Matulonis UA, Birrer MJ, Castro CM, Gilbert L, Vergote I, Martin LP, Mantia-Smaldone GM, Martin AG, Bratos R, Penson RT, Malek K, Moore KN

Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer. Gynecol Oncol. 2020;157(2):379-385 - PMID: 32081463 - DOI: 10.1016/j.ygyno.2020.01.037

Gilbert L, Oaknin A, Matulonis UA, Mantia-Smaldone GM, Lim PC, Castro CM, Provencher D, Memarzadeh S, Method M, Wang J, Moore KN, O'Malley DM

Safety and efficacy of mirvetuximab soravtansine, a folate receptor alpha (FRα))-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer. Gynecol Oncol. 2023;170:241-247 - PMID: 36736157 - DOI: 10.1016/j.ygyno.2023.01.020

Silberman JN, Bercow AS, Gockley AA, Eisenhauer EL, Sisodia R, Randall T, Del Carmen MG, Goodman A, Castro CM, Melamed A, Bregar AJ

Trends in the use of neoadjuvant chemotherapy for low-grade serous ovarian cancer in the United States. Gynecol Oncol. 2023;175:60-65 - PMID: 37327540 - DOI: 10.1016/j.ygyno.2023.06.001

Richardson DL, Moore KN, Vergote I, Gilbert L, Martin LP, Mantia-Smaldone GM, Castro CM, Provencher D, Matulonis UA, Stec J, Wang Y, Method M, O'Malley DM

Phase 1b study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate, in combination with carboplatin and bevacizumab in patients with platinum-sensitive ovarian cancer. Gynecol Oncol. 2024;185:186-193 - PMID: 38447347 - DOI: 10.1016/j.ygyno.2024.01.045

Matulonis UA, Vergote I, Moore KN, Martin LP, Castro CM, Gilbert L, Xia Y, Method M, Stec J, Birrer MJ, O'Malley DM

Safety and efficacy of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with pembrolizumab in patients with platinum-resistant ovarian cancer. Gynecol Oncol. 2025;200:96-104 - PMID: 40700855 - DOI: 10.1016/j.ygyno.2025.06.016

Stiekema LCA, Schnitzler JG, Nahrendorf M, Stroes ESG

The maturation of a 'neural-hematopoietic' inflammatory axis in cardiovascular disease. Curr Opin Lipidol. 2017;28(6):507-512 - PMID: 28877089 - DOI: 10.1097/MOL.0000000000000457

Lameijer MA, Tang J, Nahrendorf M, Beelen RH, Mulder WJ

Monocytes and macrophages as nanomedicinal targets for improved diagnosis and treatment of disease. Expert Rev Mol Diagn. 2013;13(6):567-80 - PMID: 23895127 - PMCID: PMC4110962 - DOI: 10.1586/14737159.2013.819216

Im H, Shao H, Weissleder R, Castro CM, Lee H

Nano-plasmonic exosome diagnostics. Expert Rev Mol Diagn. 2015;15(6):725-33 - PMID: 25936957 - PMCID: PMC4675626 - DOI: 10.1586/14737159.2015.1041378

Lasser T, Ntziachristos V

Optimization of 360 degrees projection fluorescence molecular tomography. Med Image Anal. 2007;11(4):389-99 - PMID: 17524701 - DOI: 10.1016/j.media.2007.04.003

Nahrendorf M, Hiller K, Hu K, Ertl G, Haase A, Bauer W

Cardiac magnetic resonance imaging in small animal models of human heart failure. Med Image Anal. 2003;7(3):369-75 - PMID: 12946475 - DOI: 10.1016/s1361-8415(03)00011-2

Paranya G, Vineberg S, Dvorin E, Kaushal S, Roth S, Rabkin E, Schoen F, Bischoff J

Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro. Am J Pathol. 2001;159:1335-43 - PMID: 11583961 - PMCID: PMC1850524 - DOI: 10.1016/s0002-9440(10)62520-5

Panchenko MP, Siddiquee Z, Dombkowski DM, Alekseyev YO, Lenburg ME, Walker JD, Macgillivray TE, Preffer FI, Stone JR

Protein Kinase CK1{alpha}LS Promotes Vascular Cell Proliferation and Intimal Hyperplasia. Am J Pathol. 2010;177(3):1562-72 - PMID: 20696773 - PMCID: PMC2928985 - DOI: 10.2353/ajpath.2010.100327

Muldoon LL, Nilaver G, Kroll RA, Pagel MA, Breakefield XO, Chiocca EA, Davidson BL, Weissleder R, Neuwelt EA

Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Am J Pathol. 1995;147(6):1840-51 - PMID: 7495307 - PMCID: PMC1869962

Mattox AK, Roelands J, Saal TM, Cheng Y, Rinchai D, Hendrickx W, Young GD, Diefenbach TJ, Berger AE, Westra WH, Bishop JA, Faquin WC, Marincola FM, Pittet MJ, Bedognetti D, Pai SI

Myeloid cells are enriched in tonsillar crypts providing insight into the host tropism of HPV. Am J Pathol. 2021;191(10):1774-1786 - PMID: 34303699 - PMCID: PMC8491092 - DOI: 10.1016/j.ajpath.2021.06.012

Sales VL, Mettler BA, Engelmayr GC, Aikawa E, Bischoff J, Martin DP, Exarhopoulos A, Moses M, Schoen FJ, Sacks M, Mayer J

Endothelial Progenitor Cells as a Sole Source for Ex vivo Seeding of Tissue-engineered Heart Valves. Tissue Eng. 2010;16(1):257-67 - PMID: 19698056 - PMCID: PMC2811057 - DOI: 10.1089/ten.TEA.2009.0424

Hjortnaes J, Gottlieb D, Figueiredo JL, Melero-Martin J, Kohler RH, Bischoff J, Weissleder R, Mayer J, Aikawa E

Intravital Molecular Imaging of Small-Diameter Tissue-Engineered Vascular Grafts: A Feasibility Study. Tissue Eng. 2010;16(4):597-607 - PMID: 19751103 - PMCID: PMC7875113 - DOI: 10.1089/ten.TEC.2009.0466

Kim J, Oh J, Peterson HM, Carlson JCT, Pittet MJ, Weissleder R

TNIK Inhibition Has Dual Synergistic Effects on Tumor and Associated Immune Cells Adv Biol (Weinh). 2022;6(8):e2200030 - PMID: 35675910 - PMCID: PMC9398996 - DOI: 10.1002/adbi.202200030

Lucas K

Cycling, Fasting, Fishing, and Other Things: The Emerging World of Biocompatible Chemistries Adv Biol (Weinh). 2022;7(1):e2200178 - PMID: 36047616 - PMCID: PMC10228596 - DOI: 10.1002/adbi.202200178

Hsia T, You DG, Politis MG, Batool SM, Ekanayake E, Lee H, Carter BS, Balaj L

Rigorous Comparison of Extracellular Vesicle Processing to Enhance Downstream Analysis for Glioblastoma Characterization. Adv Biol (Weinh). 2023;8(1):e2300233 - PMID: 37670402 - PMCID: PMC12247158 - DOI: 10.1002/adbi.202300233

Whitley MJ, Weissleder R, Kirsch DG

Tailoring Adjuvant Radiation Therapy by Intraoperative Imaging to Detect Residual Cancer. Semin Radiat Oncol. 2015;25(4):313-21 - PMID: 26384279 - PMCID: PMC4575408 - DOI: 10.1016/j.semradonc.2015.05.005

Schulz RB, Ripoll J, Ntziachristos V

Experimental fluorescence tomography of tissues with noncontact measurements. IEEE T Med Imaging. 2004;23(4):492-500 - PMID: 15084074 - DOI: 10.1109/TMI.2004.825633

Zacharakis G, Ripoll J, Weissleder R, Ntziachristos V.

Fluorescent protein tomography scanner for small animal imaging IEEE T Med Imaging. 2005;24(7):878-85 - PMID: 16011317 - DOI: 10.1109/tmi.2004.843254

Marias K, Ripoll J, Meyer H, Ntziachristos V, Orphanoudakis S.

Image analysis for assessing molecular activity changes in time-dependent geometries IEEE T Med Imaging. 2005;24(7):894-900 - PMID: 16011319 - DOI: 10.1109/tmi.2005.848612

Soubret A, Ripoll J, Ntziachristos V.

Accuracy of fluorescent tomography in the presence of heterogeneities: study of the normalized Born ratio IEEE T Med Imaging. 2005;24(10):1377-86 - PMID: 16229423 - DOI: 10.1109/tmi.2005.857213

Hyde D, Miller E, Brooks DH, Ntziachristos V

A statistical approach to inverting the Born ratio. IEEE T Med Imaging. 2007;26 (7):893-905 - PMID: 17649903 - DOI: 10.1109/TMI.2007.895467

Lasser T, Soubret A, Ripoll J, Ntziachristos V

Surface Reconstruction for free-space 360 degrees fluorescence molecular tomography and the effects of animal motion. IEEE T Med Imaging. 2008;27(2):188-94 - PMID: 18334440 - DOI: 10.1109/TMI.2007.904662

Belleannee C, Da Silva N, Shum WW, Marsolais M, Laprade R, Brown D, Breton S

Segmental Expression of the Bradykinin Type 2 Receptor in Rat Efferent Ducts and Epididymis and Its Role in the Regulation of Aquaporin 9. Biol Reprod. 2009;80(1):134-43 - PMID: 18829705 - PMCID: PMC2804812 - DOI: 10.1095/biolreprod.108.070797

Pittet MJ

Behavior of immune players in the tumor microenvironment. Curr Opin Oncol. 2009;21(1):53-9 - PMID: 19125019 - PMCID: PMC2901856 - DOI: 10.1097/CCO.0b013e32831bc38a

Jensen LJ, Schmitt BM, Berger UV, Nsumu NN, Boron WF, Hediger MA, Brown D, Breton S

Localization of sodium bicarbonate cotransporter (NBC) protein and messenger ribonucleic acid in rat epididymis. Biol Reprod. 1999;60(3):573-9 - PMID: 10026101 - DOI: 10.1095/biolreprod60.3.573

Jensen LJ, Stuart-Tilley AK, Peters LL, Lux SE, Alper SL, Breton S

Immunolocalization of AE2 anion exchanger in rat and mouse epididymis. Biol Reprod. 1999;61(4):973-80 - PMID: 10491632 - DOI: 10.1095/biolreprod61.4.973

Herak-Kramberger CM, Sabolić I, Blanusa M, Smith PJ, Brown D, Breton S

Cadmium inhibits vacuolar H(+)ATPase-mediated acidification in the rat epididymis. Biol Reprod. 2000;63(2):599-606 - PMID: 10906070 - DOI: 10.1095/biolreprod63.2.599

Herak-Kramberger CM, Breton S, Brown D, Kraus O, Sabolic I

Distribution of the vacuolar H+ atpase along the rat and human male reproductive tract. Biol Reprod. 2001;64(6):1699-707 - PMID: 11369598 - DOI: 10.1095/biolreprod64.6.1699

Pastor-Soler N, Bagnis C, Sabolic I, Tyszkowski R, McKee M, Van Hoek A, Breton S, Brown D

Aquaporin 9 expression along the male reproductive tract. Biol Reprod. 2001;65(2):384-93 - PMID: 11466204 - DOI: 10.1095/biolreprod65.2.384

Fisher JS, Pastor-Soler N, Sharpe RM, Breton S

Modulation of the onset of postnatal development of H(+)-ATPase-rich cells by steroid hormones in rat epididymis. Biol Reprod. 2002;67(4):1106-14 - PMID: 12297525 - DOI: 10.1095/biolreprod67.4.1106

Pastor-Soler N, Isnard-Bagnis C, Herak-Kramberger C, Sabolic I, Van Hoek A, Brown D, Breton S

Expression of aquaporin 9 in the adult rat epididymal epithelium is modulated by androgens. Biol Reprod. 2002;66(6):1716-22 - PMID: 12021052 - DOI: 10.1095/biolreprod66.6.1716

Da Silva N, Silberstein C, Beaulieu V, Pietrement C, Van Hoek AN, Brown D, Breton S

Postnatal expression of aquaporins in epithelial cells of the rat epididymis. Biol Reprod. 2005;74(2):427-38 - PMID: 16221990 - DOI: 10.1095/biolreprod.105.044735

Pietrement C, Sun-Wada GH, Silva ND, McKee M, Marshansky V, Brown D, Futai M, Breton S

Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis. Biol Reprod. 2005;74(1):185-94 - PMID: 16192400 - DOI: 10.1095/biolreprod.105.043752

Shum WW, Smith TB, Cortez-Retamozo V, Grigoryeva LS, Roy JW, Hill E, Pittet MJ, Breton S, Da Silva N

Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis. Biol Reprod. 2014;90(5):90 - PMID: 24648397 - PMCID: PMC4076373 - DOI: 10.1095/biolreprod.113.116681

Kim B, Roy J, Shum WW, Da Silva N, Breton S

Role of Testicular Luminal Factors on Basal Cell Elongation and Proliferation in the Mouse Epididymis. Biol Reprod. 2014;92(1):9 - PMID: 25411392 - PMCID: PMC4434934 - DOI: 10.1095/biolreprod.114.123943

Kim B, Breton S

The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis. Biol Reprod. 2015;94(1):22 - PMID: 26658708 - PMCID: PMC4809559 - DOI: 10.1095/biolreprod.115.134965

Meng C, Liu W, Huang H, Wang Y, Chen B, Freeman GJ, Schneyer A, Lin HY, Xia Y

Repulsive Guidance Molecule b (RGMb) Is Dispensable for Normal Gonadal Function in Mice. Biol Reprod. 2016;94(4):78 - PMID: 26911425 - DOI: 10.1095/biolreprod.115.135921

Park YJ, Battistone MA, Kim B, Breton S

Relative contribution of clear cells and principal cells to luminal pH in the mouse epididymis. Biol Reprod. 2017;96(2):366-375 - PMID: 28203710 - PMCID: PMC6213081 - DOI: 10.1095/biolreprod.116.144857

Kim B, Breton S

Androgens are essential for epithelial cell recovery after efferent duct ligation in the initial segment of the mouse epididymis. Biol Reprod. 2020;102(1):76-83 - PMID: 31403160 - PMCID: PMC7334622 - DOI: 10.1093/biolre/ioz152

Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R

In vivo tracking of neural progenitor cell migration to glioblastomas Hum Gene Ther. 2003;14:1247-54 - PMID: 12952596 - DOI: 10.1089/104303403767740786

Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X

Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005;16:1367-76 - PMID: 16390268 - DOI: 10.1089/hum.2005.16.1367

Messerli SM, Prabhakar S, Tang Y, Mahmood U, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006;17(1):20-30 - PMID: 16409122 - DOI: 10.1089/hum.2006.17.20

Schellingerhout D, Bogdanov A, Marecos E, Spear M, Breakefield X, Weissleder R

Mapping the in vivo distribution of herpes simplex virions. Hum Gene Ther. 1998;9(11):1543-9 - PMID: 9694153 - DOI: 10.1089/hum.1998.9.11-1543

Rainov NG, Zimmer C, Chase M, Kramm CM, Chiocca EA, Weissleder R, Breakefield XO

Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Hum Gene Ther. 1995;6(12):1543-52 - PMID: 8664379 - DOI: 10.1089/hum.1995.6.12-1543

Ji H, Wang TL, Chen CH, Pai SI, Hung CF, Lin KY, Kurman RJ, Pardoll DM, Wu TC

Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors. Hum Gene Ther. 1999;10(17):2727-40 - PMID: 10584920 - DOI: 10.1089/10430349950016474

Sabolic I, Herak-Kramberger CM, Antolovic R, Breton S, Brown D

Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin. Toxicology. 2005;218(2-3):149-63 - PMID: 16288946 - DOI: 10.1016/j.tox.2005.10.009

Iyer VR, Hahn PF, Blaszkowsky LS, Thayer SP, Halpern EF, Harisinghani MG

Added Value of Selected Images Embedded Into Radiology Reports to Referring Clinicians. J Am Coll Radiol. 2010;7(3):205-210 - PMID: 20193926 - PMCID: PMC3086392 - DOI: 10.1016/j.jacr.2009.10.014

Mitchell DG, Javitt MC, Glanc P, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Horowitz NS, Pandharipande PV, Pannu HK, Podrasky AE, Royal HD, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM

ACR Appropriateness Criteria Staging and Follow-up of Ovarian Cancer. J Am Coll Radiol. 2013;10(11):822-7 - PMID: 24183551 - DOI: 10.1016/j.jacr.2013.07.017

Vinegoni C, Lee S, Aguirre AD, Weissleder R

New techniques for motion-artifact-free in vivo cardiac microscopy. Front Physiol. 2015;6:147 - PMID: 26029116 - PMCID: PMC4428079 - DOI: 10.3389/fphys.2015.00147

Bassir SH, Garakani S, Wilk K, Aldawood ZA, Hou J, Yeh SA, Sfeir C, Lin CP, Intini G

Prx1 Expressing Cells Are Required for Periodontal Regeneration of the Mouse Incisor. Front Physiol. 2019;10:591 - PMID: 31231227 - PMCID: PMC6558369 - DOI: 10.3389/fphys.2019.00591

McCullar KS, Abbaspour S, Wang W, Aguirre AD, Westover MB, Klerman EB

Timing of diuretic administration effects on urine volume in hospitalized patients. Front Physiol. 2024;14:1208324 - PMID: 38321985 - PMCID: PMC10844419 - DOI: 10.3389/fphys.2023.1208324

Magudia K, Lee RS, Dibble EH, Parris D, Baniel CC, Beltran Ponce S, Laur O, Hamman S, Arleo EK, Johnstone C, Lightfoote J, Rubin E, Deitte L, Jagsi R, Kotsenas AL, Ng TSC

The State of Paid Family and Medical Leave Policies: An ACR, AAWR, SWRO Member Survey. J Am Coll Radiol. 2025;22(7):831-837 - PMID: 40174871 - DOI: 10.1016/j.jacr.2025.03.006

Davis RW, Brannen AD, Hossain MJ, Monsma S, Bock PE, Nahrendorf M, Mead D, Lodes M, Liles MR, Panizzi P

Complete genome of Staphylococcus aureus Tager 104 provides evidence of its relation to modern systemic hospital-acquired strains. BMC Genomics. 2016;17(1):179 - PMID: 26940863 - PMCID: PMC4778325 - DOI: 10.1186/s12864-016-2433-8

Kim H, Wei Y, Lee JY, Wu Y, Zheng Y, Moskowitz MA, Chen JW

Myeloperoxidase inhibition increases neurogenesis after ischemic stroke. J Pharmacol Exp Ther. 2016;359(2):262-272 - PMID: 27550713 - PMCID: PMC5074486 - DOI: 10.1124/jpet.116.235127

Wang CY, Babitt JL

Hepcidin regulation in the anemia of inflammation. Curr Opin Hematol. 2016;23(3):189-197 - PMID: 26886082 - PMCID: PMC4993159 - DOI: 10.1097/MOH.0000000000000236

Montet X, Yuan H, Weissleder R, Josephson L

Enzyme-based visualization of receptor-ligand binding in tissues. Lab Invest. 2006;86(5):517-25 - PMID: 16568109 - DOI: 10.1038/labinvest.3700404

Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA

Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer. Lab Invest. 2006;86(6):599-609 - PMID: 16607378 - DOI: 10.1038/labinvest.3700421

Deguchi JO, Huang H, Libby P, Aikawa E, Whittaker P, Sylvan J, Lee RT, Aikawa M

Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II. Lab Invest. 2009;89(3):315-26 - PMID: 19153555 - PMCID: PMC2932654 - DOI: 10.1038/labinvest.2008.167

Larson AM, Hedgire SS, Deshpande V, Stemmer-Rachamimov AO, Harisinghani MG, Ferrone CR, Shah U, Thiele EA

Pancreatic neuroendocrine tumors in patients with tuberous sclerosis complex. Clin Genet. 2011;82(6):558-63 - PMID: 22035404 - DOI: 10.1111/j.1399-0004.2011.01805.x

Lienard D, Rimoldi D, Marchand M, Dietrich P, van Baren N, Geldhof C, Batard P, Guillaume P, Ayyoub M, Pittet M, Zippelius A, Fleischhauer K, Lejeune F, Cerottini J, Romero P, Speiser D

Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA. Cancer Immunol Immunther. 2004;4:4 - PMID: 15149168

Li A, Wu Y, Linnoila J, Pulli B, Wang C, Zeller M, Ali M, Lewandrowski GK, Li J, Tricot B, Keliher E, Wojtkiewicz GR, Fulci G, Feng X, Tannous BA, Yao Z, Chen JW

Surface biotinylation of cytotoxic T lymphocytes for in vivo tracking of tumor immunotherapy in murine models. Cancer Immunol Immunther. 2016;65(12):1545-1554 - PMID: 27722909 - PMCID: PMC5101144 - DOI: 10.1007/s00262-016-1911-9

Yu S, Liao KP, Shaw SY, Gainer VS, Churchill SE, Szolovits P, Murphy SN, Kohane IS, Cai T

Toward high-throughput phenotyping: unbiased automated feature extraction and selection from knowledge sources. J Am Med Inform Assoc. 2015;22(5):993-1000 - PMID: 25929596 - PMCID: PMC4986664 - DOI: 10.1093/jamia/ocv034

Swirski FK, Nahrendorf M

Imaging macrophage development and fate in atherosclerosis and myocardial infarction. Immunol Cell Biol. 2013;91(4):297-303 - PMID: 23207281 - PMCID: PMC3875224 - DOI: 10.1038/icb.2012.72

Kang HW, Weissleder R, Bogdanov A Jr

Targeting of MPEG-protected polyamino acid carrier to human E-selectin in vitro Amino Acids. 2002;23:301-8 - PMID: 12373551 - DOI: 10.1007/s00726-001-0142-2

Pham W, Lai WF, Weissleder R, Tung CH

High efficiency synthesis of a bioconjugatable near-infrared fluorochrome Bioconjug Chem. 2003;14:1048-51 - PMID: 13129411 - DOI: 10.1021/bc034070h

Moon, WK, Lin Y, O'Loughlin T, Tang Y, Kim DE, Weissleder R, Tung CH

Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate Bioconjug Chem. 2003;14:539-45 - PMID: 12757377 - DOI: 10.1021/bc0340114

Koch AM, Reynolds F, Kircher MF, Merkle HP, Weissleder R, Josephson L

Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells Bioconjug Chem. 2003;14:1115-21 - PMID: 14624624 - DOI: 10.1021/bc034123v

Zhao M, Kircher MF, Josephson L, Weissleder R

Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake Bioconjug Chem. 2002;13:840-4 - PMID: 12121140 - DOI: 10.1021/bc0255236

Wunderbaldinger P, Josephson L, Weissleder R

Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles Bioconjug Chem. 2002;13:264-8 - PMID: 11906263 - DOI: 10.1021/bc015563u

Lin Y, Weissleder R, Tung CH

Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation Bioconjug Chem. 2002;13:605-10 - PMID: 12009952 - DOI: 10.1021/bc0155723

Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov A Jr

Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture Bioconjug Chem. 2002;13:122-7 - PMID: 11792187 - DOI: 10.1021/bc0155521

Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R

Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes Bioconjug Chem. 2002;13:554-60 - PMID: 12009946 - DOI: 10.1021/bc015555d

Hogemann D, Ntziachristos V, Josephson L, Weissleder R

High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes Bioconjug Chem. 2002;13:116-21 - PMID: 11792186 - DOI: 10.1021/bc015549h

Weissleder R, Bogdanov A Jr, Tung CH, Weinmann HJ

Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging Bioconjug Chem. 2001;12:213-9 - PMID: 11312682 - DOI: 10.1021/bc000091p

Hogemann D, Josephson L, Weissleder R, Basilion JP

Improvement of MRI probes to allow efficient detection of gene expression Bioconjug Chem. 2000;11:941-6 - PMID: 11087345 - DOI: 10.1021/bc000079x

Bhorade R, Weissleder R, Nakakoshi T, Moore A, Tung CH

Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide Bioconjug Chem. 2000;11:301-5 - PMID: 10821645 - DOI: 10.1021/bc990168d

Tung CH, Bredow S, Mahmood U, Weissleder R

Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging Bioconjug Chem. 1999;10:892-6 - PMID: 10502358 - DOI: 10.1021/bc990052h

Josephson L, Tung CH, Moore A, Weissleder R

High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates Bioconjug Chem. 1999;10:186-91 - PMID: 10077466 - DOI: 10.1021/bc980125h

Kircher MF, Weissleder R, Josephson L

A dual fluorochrome probe for imaging proteases Bioconjug Chem. 2004;15:242-8 - PMID: 15025519 - DOI: 10.1021/bc034151d

Banerjee P, Reichardt W, Weissleder R, Bogdanov A Jr

Novel hyperbranched dendron for gene transfer in vitro and in vivo. Bioconjug Chem. 2004;15(5):960-8 - PMID: 15366948 - DOI: 10.1021/bc0342128

Schellenberger EA, Sosnovik D, Weissleder R, Josephson L

Magneto/Optical annexin v, a multimodal protein. Bioconjug Chem. 2004;15(5):1062-7 - PMID: 15366960 - DOI: 10.1021/bc049905i

Pham W, Choi Y, Weissleder R, Tung CH

Developing a Peptide-Based Near-Infrared Molecular Probe for Protease Sensing. Bioconjug Chem. 2004;15(6):1403-1407 - PMID: 15546208 - DOI: 10.1021/bc049924s

Metelev V, Weissleder R, Bogdanov A Jr

Synthesis and Properties of Fluorescent NF-kappaB-Recognizing Hairpin Oligodeoxyribonucleotide Decoys. Bioconjug Chem. 2004;15(6):1481-1487 - PMID: 15546218 - DOI: 10.1021/bc049916b

Tsourkas A, Shinde-Patil VR, Kelly KA, Patel P, Wolley A, Allport JR, Weissleder R.

In Vivo Imaging of Activated Endothelium Using an Anti-VCAM-1 Magneto optical Probe Bioconjug Chem. 2005;(3):576-581 - PMID: 15898724 - DOI: 10.1021/bc050002e

Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L.

Synthesis and Activity of C11-Modified Wortmannin Probes for P13 Kinase Bioconjug Chem. 2005;(3):669-675 - PMID: 15898736 - DOI: 10.1021/bc049714f

Reynolds F, Weissleder R, Josephson L.

Protamine as an efficient membrane-translocating Peptide Bioconjug Chem. 2005;16(5):1240-5 - PMID: 16173804 - DOI: 10.1021/bc0501451

Hilderbrand SA, Kelly KA, Weissleder R, Tung CH.

Monofunctional near-infrared fluorochromes for imaging applications Bioconjug Chem. 2005;16(5):1275-81 - PMID: 16173808 - DOI: 10.1021/bc0501799

Sun EY, Josephson L, Kelly KA, Weissleder R

Development of nanoparticle libraries for biosensing. Bioconjug Chem. 2006;17(1):109-13 - PMID: 16417258 - DOI: 10.1021/bc050290e

Banerjee P, Weissleder R, Bogdanov A

Linear Polyethyleneimine Grafted to a Hyperbranched Poly(ethylene glycol)-like Core: A Copolymer for Gene Delivery. Bioconjug Chem. 2006;17(1):125-31 - PMID: 16417260 - DOI: 10.1021/bc050083e

Galande A, Weissleder R, Tung CH.

Fluorescence Probe with a pH-Sensitive Trigger Bioconjug Chem. 2006;17 (2):255-257 - PMID: 16536452 - DOI: 10.1021/bc050330e

Montet X, Weissleder R, Josephson L.

Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas Bioconjug Chem. 2006;17(4):905-911 - PMID: 16848396 - DOI: 10.1021/bc060035+

Lai KS, Ho NH, Cheng JD, Tung CH

Selective Fluorescence Probes for Dipeptidyl Peptidase Activity-Fibroblast Activation Protein and Dipeptidyl Peptidase IV. Bioconjug Chem. 2007;18(4):1246-50 - PMID: 17489551 - PMCID: PMC2562575 - DOI: 10.1021/bc0603586

Kim GY, Josephson L, Langer R, Cima MJ

Magnetic Relaxation Switch Detection of Human Chorionic Gonadotrophin. Bioconjug Chem. 2007;18(6):2024-8 - PMID: 17892270 - DOI: 10.1021/bc070110w

Law B, Weissleder R, Tung CH

Protease-Sensitive Fluorescent Nanofibers. Bioconjug Chem. 2007;(18) 6 ::1701-1704 - PMID: 17915958 - PMCID: PMC2528070 - DOI: 10.1021/bc070054z

Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L

Fate of a Bioactive Fluorescent Wortmannin Derivative in Cells. Bioconjug Chem. 2007;19:130-137 - PMID: 17988080 - DOI: 10.1021/bc7002204

Hilderbrand SA, Kelly KA, Niedre M, Weissleder R

Near Infrared Fluorescence-Based Bacteriophage Particles for Ratiometric pH Imaging. Bioconjug Chem. 2008;19(8):1635-9 - PMID: 18666791 - PMCID: PMC2705288 - DOI: 10.1021/bc800188p

Shao F, Weissleder R, Hilderbrand SA

Monofunctional Carbocyanine Dyes for Bio- and Bioorthogonal Conjugation. Bioconjug Chem. 2008;19(12): :2487-2491 - PMID: 19053316 - PMCID: PMC2656649 - DOI: 10.1021/bc800417b

Devaraj N, Weissleder R, Hilderbrand S

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging. Bioconjug Chem. 2008;19(12):2297-2299 - PMID: 19053305 - PMCID: PMC2677645 - DOI: 10.1021/bc8004446

Garanger E, Weissleder R, Josephson L

A Multifunctional Single-Attachment-Point Reagent for Controlled Protein Biotinylation. Bioconjug Chem. 2009;20(1):170-173 - PMID: 19072220 - PMCID: PMC2692913 - DOI: 10.1021/bc800392t

Devaraj NK*, Keliher EJ*, Thurber GM, Nahrendorf M, Weissleder R

(18)F Labeled Nanoparticles for in Vivo PET-CT Imaging. Bioconjug Chem. 2009;20(2):397-401 - PMID: 19138113 - PMCID: PMC2644737 - DOI: 10.1021/bc8004649

McCarthy JR, Patel P, Botnaru I, Haghayeghi P, Weissleder R, Jaffer FA

Multimodal Nanoagents for the Detection of Intravascular Thrombi. Bioconjug Chem. 2009;20(6):1251-5 - PMID: 19456115 - PMCID: PMC2733224 - DOI: 10.1021/bc9001163

Smith RA, Yuan H, Weissleder R, Cantley LC, Josephson L

A Wortmannin-Cetuximab as a Double Drug. Bioconjug Chem. 2009;20 :2185-2189 - PMID: 19883074 - PMCID: PMC3386608 - DOI: 10.1021/bc900176a

Tassa C, Duffner JL, Lewis TA, Weissleder R, Schreiber SL, Koehler AN, Shaw SY

Binding Affinity and Kinetic Analysis of Targeted Small Molecule-Modified Nanoparticles Bioconjug Chem. 2010;21:14-19 - PMID: 20028085 - PMCID: PMC2902264 - DOI: 10.1021/bc900438a

Reiner T, Kohler RH, Liew CW, Hill JA, Gaglia J, Kulkarni RN, Weissleder R

Near-Infrared Fluorescent Probe for Imaging of Pancreatic B Cells Bioconjug Chem. 2010;21:1362-1368 - PMID: 20583828 - PMCID: PMC2912453 - DOI: 10.1021/bc100184w

Marecos E, Weissleder R, Bogdanov A

Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model. Bioconjug Chem. 1998;9(2):184-91 - PMID: 9548533 - DOI: 10.1021/bc970146w

Shen TT, Bogdanov A, Bogdanova A, Poss K, Brady TJ, Weissleder R

Magnetically labeled secretin retains receptor affinity to pancreas acinar cells. Bioconjug Chem. 1996;7(3):311-6 - PMID: 8816953 - DOI: 10.1021/bc960003u

Bogdanov AA, Martin C, Bogdanova AV, Brady TJ, Weissleder R

An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties. Bioconjug Chem. 1996;7(1):144-9 - PMID: 8742003 - DOI: 10.1021/bc950089b

Zeglis BM, Mohindra P, Weissmann GI, Divilov V, Hilderbrand SA, Weissleder R, Lewis JS

A Modular Strategy for the Construction of Radiometallated Antibodies for Positron Emission Tomography Based on Inverse Electron Demand Diels-Alder Click Chemistry. Bioconjug Chem. 2011;22(10):2048-59 - PMID: 21877749 - PMCID: PMC3197258 - DOI: 10.1021/bc200288d

Karver M, Weissleder R, Hilderbrand SA

Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation. Bioconjug Chem. 2011;22(11):2263-2270 - PMID: 21950520 - PMCID: PMC3254257 - DOI: 10.1021/bc200295y

Keliher E, Yoo J, Nahrendorf M, Lewis JS, Marinelli B, Newton A, Pittet M, Weissleder R

89Zr Labeled Dextran Nanoparticles Enable in vivo Macrophage Imaging. Bioconjug Chem. 2011;22(12):2383-9 - PMID: 22035047 - PMCID: PMC3244512 - DOI: 10.1021/bc200405d

Liong M, Fernandez-Suarez M, Issadore D, Min C, Tassa C, Reiner T, Fortune SM, Toner M, Lee H, Weissleder R

Specific Pathogen Detection Using Bioorthogonal Chemistry and Diagnostic Magnetic Resonance. Bioconjug Chem. 2011;22(12):2390-4 - PMID: 22043803 - PMCID: PMC3263317 - DOI: 10.1021/bc200490r

Lu X, Agasti SS, Vinegoni C, Waterman P, Depinho R, Weissleder R

Optochemogenetics (OCG) allows more precise control of genetic engineering in mice with CreER regulators. Bioconjug Chem. 2012;23(9):1945-51 - PMID: 22917215 - PMCID: PMC3775343 - DOI: 10.1021/bc300319c

Clardy SM, Keliher EJ, Mohan JF, Sebas M, Benoist C, Mathis D, Weissleder R

Fluorescent Exendin-4 Derivatives for Pancreatic β-Cell Analysis. Bioconjug Chem. 2013;25(1):171-177 - PMID: 24328216 - PMCID: PMC4016126 - DOI: 10.1021/bc4005014

Courtis AM, Santos SA, Guan Y, Hendricks JA, Ghosh B, Szantai-Kis DM, Reis SA, Shah JV, Mazitschek R

Monoalkoxy BODIPYs - A Fluorophore Class for Bioimaging. Bioconjug Chem. 2014;25(6):1043-51 - PMID: 24797834 - PMCID: PMC4215867 - DOI: 10.1021/bc400575w

Sprachman M, Laughney A, Kohler R, Weissleder R

In Vivo Imaging of Multidrug Resistance Using a Third Generation MDR1 Inhibitor. Bioconjug Chem. 2014;25(6):1137-42 - PMID: 24806886 - PMCID: PMC4098115 - DOI: 10.1021/bc500154c

Brand C, Abdel-Atti D, Zhang Y, Carlin S, Clardy SM, Keliher EJ, Weber WA, Lewis JS, Reiner T

In Vivo Imaging of GLP-1R with a Targeted Bimodal PET/Fluorescence Imaging Agent. Bioconjug Chem. 2014;25(7):1323-30 - PMID: 24856928 - PMCID: PMC4215873 - DOI: 10.1021/bc500178d

Giedt RJ, Sprachman M, Yang K, Weissleder R

Imaging cellular distribution of Bcl inhibitors using small molecule drug conjugates. Bioconjug Chem. 2014;25(11):2081-2085 - PMID: 25333750 - PMCID: PMC4240345 - DOI: 10.1021/bc500433k

Kim E, Yang K, Kohler R, Dubach JM, Mikula H, Weissleder R

Optimized Near-IR fluorescent agents for in vivo imaging of Btk expression. Bioconjug Chem. 2015;26(8):1513-1518 - PMID: 26017814 - PMCID: PMC4772718 - DOI: 10.1021/acs.bioconjchem.5b00152

Park YI, Im H, Weissleder R, Lee H

Nanostar clustering improves the sensitivity of plasmonic assays. Bioconjug Chem. 2015;26(8):1470-1474 - PMID: 26102604 - PMCID: PMC5292976 - DOI: 10.1021/acs.bioconjchem.5b00343

Meimetis LG, Boros E, Carlson JC, Ran C, Caravan P, Weissleder R

Bioorthogonal fluorophore linked DFO - Technology enabling facile chelator quantification and multimodal imaging of antibodies. Bioconjug Chem. 2015;27(1):257-63 - PMID: 26684717 - PMCID: PMC4858350 - DOI: 10.1021/acs.bioconjchem.5b00630

Park YI, Kim E, Huang CH, Park KS, Castro CM, Lee H, Weissleder R

Facile Coating Strategy to Functionalize Inorganic Nanoparticles for Biosensing Bioconjug Chem. 2017;28(1):33-37 - PMID: 27792877 - PMCID: PMC5474933 - DOI: 10.1021/acs.bioconjchem.6b00524

Ahmed MS, Rodell CB, Hulsmans M, Kohler RH, Aguirre A, Nahrendorf M, Weissleder R

A Supramolecular Nanocarrier for Delivery of Amiodarone Anti-Arrhythmic Therapy to the Heart. Bioconjug Chem. 2019;30(3):733-740 - PMID: 30615425 - PMCID: PMC6483069 - DOI: 10.1021/acs.bioconjchem.8b00882

Marquard AN, Carlson JCT, Weissleder R

Expanding the scope of antibody rebridging with new pyridazinedione-TCO constructs. Bioconjug Chem. 2020;31(6):1616-1623 - PMID: 32286045 - PMCID: PMC7788567 - DOI: 10.1021/acs.bioconjchem.0c00155

Quintana JM, Arboleda D, Hu H, Scott E, Luthria G, Pai S, Parangi S, Weissleder R, Miller MA

Radiation Cleaved Drug-Conjugate Linkers Enable Local Payload Release. Bioconjug Chem. 2022;33(8):1474-1484 - PMID: 35833631 - PMCID: PMC9390333 - DOI: 10.1021/acs.bioconjchem.2c00174

Quintana JM, Carlson JCT, Scott E, Ng TSC, Miller MA, Weissleder R

Scission-Enhanced Molecular Imaging (SEMI). Bioconjug Chem. 2024;35(10):1543-52 - PMID: 39255972 - PMCID: PMC11488501 - DOI: 10.1021/acs.bioconjchem.4c00337

Deutsch-Williams RJ, Schleyer KA, Das R, Carrothers JE, Kohler RH, Vinegoni C, Weissleder R

FAP-Targeted Fluorescent Imaging Agents to Study Cancer-Associated Fibroblasts In Vivo. Bioconjug Chem. 2024;36(1):44-53 - PMID: 39667730 - PMCID: PMC11740949 - DOI: 10.1021/acs.bioconjchem.4c00426

Simpson GG, Quintana JM, Carrothers JE, Jiang F, Walker SA, Cho C, Weissleder R, Miller MA, Ng TSC

Fluorescent PSMA-Targeted Radiotheranostic Compounds for Multiscale Imaging. Bioconjug Chem. 2025;36(7):1448-1460 - PMID: 40574660 - PMCID: PMC12365983 - DOI: 10.1021/acs.bioconjchem.5c00139

Rabinowitz Z, Deutsch-Williams RJ, Weissleder R

Far-Red Spray-On Imaging Probes for FAP-Targeted Cancer Surgery Bioconjug Chem. 2025;36(11):2410-2422 - PMID: 41147981 - DOI: 10.1021/acs.bioconjchem.5c00420

Koch PD, Quintana J, Ahmed M, Kohler RH, Weissleder R

Small Molecule Imaging Agent For Mutant Kras G12C Adv Ther (Weinh). 2021;4(5):ePub - PMID: 33997272 - PMCID: PMC8115719 - DOI: 10.1002/adtp.202000290

Rodell CB, Baldwin P, Fernandez B, Weissleder R, Sridhar S, Dubach JM

Quantification of Cellular Drug Biodistribution Addresses Challenges in Evaluating in vitro and in vivo Encapsulated Drug Delivery. Adv Ther (Weinh). 2020;4(3):ePub - PMID: 33997266 - PMCID: PMC8114878 - DOI: 10.1002/adtp.202000125

Chang JYH, Agarwal Y, Rodrigues KA, Momin N, Ni K, Read BJ, Moyer TJ, Mehta NK, Silva M, Suh H, Melo MB, Wittrup KD, Irvine DJ

Co-Anchoring of Engineered Immunogen and Immunostimulatory Cytokines to Alum Promotes Enhanced-Humoral Immunity. Adv Ther (Weinh). 2022;5(7):2100235 - PMID: 36311814 - PMCID: PMC9595138 - DOI: 10.1002/adtp.202100235

Yoshida S, Kurokohchi K, Ueno T, Yoshino M, Shimada M, Masaki T

Hepatic von Meyenburg complex: a trigger of severe portal hypertension. Liver Int. 2008;29(4):614-5 - PMID: 19018981 - PMCID: PMC2711260 - DOI: 10.1111/j.1478-3231.2008.01903.x

Krapf D, Chun Ruan Y, Wertheimer EV, Battistone MA, Pawlak JB, Sanjay A, Pilder SH, Cuasnicu P, Breton S, Visconti PE

cSrc is necessary for epididymal development and is incorporated into sperm during epididymal transit. Dev Biol. 2012;369(1):43-53 - PMID: 22750823 - PMCID: PMC3424100 - DOI: 10.1016/j.ydbio.2012.06.017

Shah K, Weissleder R

Molecular Optical Imaging: Applications Leading to the Development of Present Day Therapeutics NeuroRx. 2005;2:215-225 - PMID: 15897946 - PMCID: PMC1064987 - DOI: 10.1602/neurorx.2.2.215

Brown D, Hasler U, Nunes P, Bouley R, Lu H

Phosphorylation events and the modulation of aquaporin 2 cell surface expression. Curr Opin Nephrol Hypertens. 2008;17(5):491-8 - PMID: 18695390 - PMCID: PMC3774073 - DOI: 10.1097/MNH.0b013e3283094eb1

Comper WD, Russo LM

The glomerular filter: an imperfect barrier is required for perfect renal function. Curr Opin Nephrol Hypertens. 2009;18(4):336-42 - PMID: 19474730 - DOI: 10.1097/MNH.0b013e32832cb96a

Marshansky V, Ausiello DA, Brown D

Physiological importance of endosomal acidification: potential role in proximal tubulopathies. Curr Opin Nephrol Hypertens. 2002;11(5):527-37 - PMID: 12187318 - DOI: 10.1097/00041552-200209000-00009

Babitt JL, Sitara D

Crosstalk between fibroblast growth factor 23, iron, erythropoietin, and inflammation in kidney disease. Curr Opin Nephrol Hypertens. 2019;28(4):304-310 - PMID: 31145704 - PMCID: PMC6693648 - DOI: 10.1097/MNH.0000000000000514

Xu C, Mu L, Roes I, Miranda-Nieves D, Nahrendorf M, Ankrum JA, Zhao W, Karp JM

Nanoparticle-based monitoring of cell therapy. Nanotechnology. 2011;22(49):494001 - PMID: 22101191 - PMCID: PMC3334527 - DOI: 10.1088/0957-4484/22/49/494001

Huang X, Li Y, Im H, Yarimaga O, Kim J, Jang D, Cho S, Cai W, Choi Y

Morphology-controlled SWCNT/polymeric microsphere arrays by a wet chemical self-assembly technique and their application for sensors Nanotechnology. 2006;17(12):2988

Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U

Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2008;44:190-198 - PMID: 19007918 - PMCID: PMC2656637 - DOI: 10.1016/j.bone.2008.10.036

Wunderbaldinger P, Josephson L, Weissleder R

Crosslinked iron oxides (CLIO): a new platform for the development of targeted MR contrast agents Acad Radiol. 2002;9 Suppl 2:S304-6 - PMID: 12188255 - DOI: 10.1016/s1076-6332(03)80210-6

Schellenberger EA, Hogemann D, Josephson L, Weissleder R

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Acad Radiol. 2002;9 Suppl 2:S310-1 - PMID: 12188257 - DOI: 10.1016/s1076-6332(03)80212-x

Ntziachristos, V, Bremer C, Tung C, Weissleder R

Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT) Acad Radiol. 2002;9 Suppl 2:S323-5 - PMID: 12188262 - DOI: 10.1016/s1076-6332(03)80217-9

Mahmood U, Weissleder R

Some tools for molecular imaging Acad Radiol. 2002;9:629-31 - PMID: 12061735 - DOI: 10.1016/s1076-6332(03)80306-9

Harisinghani MG, Barentsz JO, Hahn PF, Deserno W, de la Rosette J, Saini S, Marten K, Weissleder R

MR lymphangiography for detection of minimal nodal disease in patients with prostate cancer Acad Radiol. 2002;9 Suppl 2:S312-3 - PMID: 12188258 - DOI: 10.1016/s1076-6332(03)80213-1

Bremer C, Tung CH, Weissleder R

Molecular imaging of MMP expression and therapeutic MMP inhibition Acad Radiol. 2002;9 Suppl 2:S314-5 - PMID: 12188259 - DOI: 10.1016/s1076-6332(03)80214-3

Wagenaar DJ, Weissleder R, Hengerer A

Glossary of molecular imaging terminology Acad Radiol. 2001;8:409-20 - PMID: 11345272 - DOI: 10.1016/S1076-6332(03)80549-4

Bremer C, Weissleder R

In vivo imaging of gene expression Acad Radiol. 2001;8:15-23 - PMID: 11201452 - DOI: 10.1016/s1076-6332(03)80739-0

Harisinghani MG, Saini S, Hahn PF, Weissleder R, Mueller PR

MR imaging of lymph nodes in patients with primary abdominal and pelvic malignancies using ultrasmall superparamagnetic iron oxide (Combidex). Acad Radiol. 1998;5 Suppl 1:S167-9, discussion S183-4 - PMID: 9561072 - DOI: 10.1016/s1076-6332(98)80095-0

Hartman RI, Chang CY, Wo JY, Eisenberg JD, Hong TS, Harisinghani MG, Gazelle GS, Pandharipande PV

Optimizing Adjuvant Treatment Decisions for Stage T2 Rectal Cancer Based on Mesorectal Node Size: A Decision Analysis. Acad Radiol. 2012;20(1):79-89 - PMID: 22947271 - PMCID: PMC3525763 - DOI: 10.1016/j.acra.2012.07.010

Trinh K, Chow DZ, Park H, Habib U, Offit L, Franquet E, Almeida RR, Wang Y, Borges N, Jamal F, Jacene HA, Heidari P, Ng TSC

Evaluating the added value of concurrent contrast-enhanced diagnostic CT for PSMA-PET/CT Interpretation. Acad Radiol. 2024;32(1):275-286 - PMID: 39147641 - PMCID: PMC12173529 - DOI: 10.1016/j.acra.2024.08.008

Vinegoni C, Ralston T, Tan W, Luo W, Marks DL, Boppart SA

Integrated structural and functional imaging combining spectral-domain optical coherence and multiphoton microscopy Appl Phys Lett. 2006;88:051105

Marks DL, Vinegoni C, Bredfeldt JS, Boppart SA

Interferometric differentiation between resonant Coherent Anti-Stokes Raman Scattering and nonresonant four-wave-mixing processes Appl Phys Lett. 2004;85:5787-89

Pellegrini V, Colombelli R, Vinegoni C, Rubini S, Lantier R, Franciosi A, Beltram F, Pavesi L

Second harmonic generation in ZnSe microcavity. Appl. Phys. Lett. 1999;74:1945-47 Appl Phys Lett. 1999;74:1945-47

Cazzanelli M, Cole D, Donegan JF, Lunney JG, Middleton PG, O'Donnell KP, Vinegoni C, Pavesi L

Photoluminescence of localized excitons in pulsed laser deposited GaN Appl Phys Lett. 1998;73:3390-2

Hooper B, Domankevitz Y, Anderson R, Lin CP

Optical temperature probe Appl Phys Lett. 2001;78:2381-3

Lin CP, Kelly MW

Cavitation and acoustic emission around laser-heated microparticles Appl Phys Lett. 1998;72:2800

Hunt TP, Lee H, and Westervelt RM

Addressable micropost array for the dielectrophoretic manipulation of particles in fluid Appl Phys Lett. 0;85(26):6421-23

Lee H, Purdon AM, Westervelt RM

Manipulation of biological cells using a microelectromagnet matrix Appl Phys Lett. 0;85(6):1063-65

Fass DM, Shah R, Ghosh B, Hennig K, Norton S, Zhao WN, Reis SA, Klein PS, Mazitschek R, Maglathlin RL, Lewis TA, Haggarty SJ

Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. ACS Med Chem Lett. 2010;2(1):39-42 - PMID: 21874153 - PMCID: PMC3161516 - DOI: 10.1021/ml1001954

Lesuffleur A, Im H, Lindquist NC, Oh S

Periodic nanohole arrays with shape-enhanced plasmon resonance as real-time biosensors Appl Phys Lett. 2007;90:243110

Taktak S, Weissleder R, Josephson L

Electrode Chemistry Yields a Nanoparticle-Based NMR Sensor for Calcium. Langmuir. 2008;24 (14):7596-7598 - PMID: 18558729 - PMCID: PMC2748273 - DOI: 10.1021/la8006298

Huang XJ, Ryu SW, Im HS, Choi YK

Wet chemical needlelike assemblies of single-walled carbon nanotubes on a silicon surface. Langmuir. 2007;23(3):991-4 - PMID: 17241002 - DOI: 10.1021/la063144l

Smith RN, Ueno T, Ito T, Tanaka K, Shea SP, Abdi R

Chemokines and chronic heart allograft rejection. Transplantation. 2007;84(3):442-4 - PMID: 17700176 - DOI: 10.1097/01.tp.0000277535.02541.30

Ueno T, Yamada A, Ito T, Yeung MY, Gorbatov R, Shimizu T, Abdi R, Sayegh MH, Auchincloss H, Najafian N

Role of Nuclear Factor of Activated T Cell (NFAT) Transcription Factors in Skin and Vascularized Cardiac Allograft Rejection. Transplantation. 2011;92(5):e26-e27 - PMID: 21866037 - DOI: 10.1097/TP.0b013e318228061c

Tremblay J, Chen H, Peng J, Kunes J, Vu MD, Der Sarkissian S, deBlois D, Bolton AE, Gaboury L, Marshansky V, Gouadon E, Hamet P

Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy. Transplantation. 2002;74(10):1425-33 - PMID: 12451244 - DOI: 10.1097/00007890-200211270-00015

Ansari MJ, Fiorina P, Dada S, Guleria I, Ueno T, Yuan X, Trikudanathan S, Smith RN, Freeman G, Sayegh MH

Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. Clin Immunol. 2007;126(2):140-7 - PMID: 17889619 - DOI: 10.1016/j.clim.2007.07.019

Pirri P, Vinegoni C, Pavesi L

Optical and photoluminescence properties of a-Si(1-x)Nx:H films deposited by PECVD Phys Rev B. 2000;61:4693-8

Giorgis F, Pirri CF, Vinegoni C, Pavesi L

Luminescence processes in amorphous silicon-nitride nanometric multilayers Phys Rev B. 1999;60:11572-76

Nahrendorf M, Weissleder R, Ertl G

Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction? PLoS ONE. 2006;1:e48 - PMID: 17183677 - PMCID: PMC1762326 - DOI: 10.1371/journal.pone.0000048

Kelly KA, Carson J, McCarthy JR, Weissleder R

Novel Peptide Sequence ("IQ-tag") with High Affinity for NIR Fluorochromes Allows Protein and Cell Specific Labeling for In Vivo Imaging. PLoS ONE. 2007;2:e665 - PMID: 17653285 - PMCID: PMC1919420 - DOI: 10.1371/journal.pone.0000665

Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R

A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. PLoS ONE. 2007;2(10):e1075 - PMID: 17957257 - PMCID: PMC2034600 - DOI: 10.1371/journal.pone.0001075

Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Plough HL, Barrett TA, Weissleder R, Khazaie K

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS ONE. 2008;3:e2916 - PMID: 18698347 - PMCID: PMC2488397 - DOI: 10.1371/journal.pone.0002916

Badr C, Hewett J, Breakefield X, Tannous B

A Highly Sensitive Assay for Monitoring the Secretory Pathway and ER Stress PLoS ONE. 0;6:e571

Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L

BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. PLoS ONE. 2008;3(12):e3949 - PMID: 19079609 - PMCID: PMC2597248 - DOI: 10.1371/journal.pone.0003949

Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S

The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS ONE. 2009;4(2):e4471 - PMID: 19214237 - PMCID: PMC2637605 - DOI: 10.1371/journal.pone.0004471

Wildgruber M, Lee H, Chudnovskiy A, Yoon T, Etzrodt M, Pittet M, Nahrendorf M, Croce K, Libby P, Weissleder R, Swirski F

Monocyte subset dynamics in human atherosclerosis can be profiled with magnetic nano-sensors. PLoS ONE. 2009;4(5):e5663 - PMID: 19461894 - PMCID: PMC2680949 - DOI: 10.1371/journal.pone.0005663

Wadlow RC, Wittner BS, Finley SA, Bergquist H, Upadhyay R, Finn S, Loda M, Mahmood U, Ramaswamy S

Systems-level modeling of cancer-fibroblast interaction. PLoS ONE. 2009;4(9):e6888 - PMID: 19727395 - PMCID: PMC2731225 - DOI: 10.1371/journal.pone.0006888

Thurber GM, Figueiredo JL, Weissleder R

Multicolor Fluorescent Intravital Live Microscopy (FILM) for Surgical Tumor Resection in a Mouse Xenograft Model. PLoS ONE. 2009;4(11):e8053 - PMID: 19956597 - PMCID: PMC2779447 - DOI: 10.1371/journal.pone.0008053

Miranda KC, Karet FE, Brown D

An Extended Nomenclature for Mammalian V-ATPase Subunit Genes and Splice Variants. PLoS ONE. 2010;5(3):e9531 - PMID: 20224822 - PMCID: PMC2835735 - DOI: 10.1371/journal.pone.0009531

Bratlie KM, Dang TT, Lyle S, Nahrendorf M, Weissleder R, Langer R, Anderson DG

Rapid biocompatibility analysis of materials via in vivo fluorescence imaging of mouse models. PLoS ONE. 2010;5(4):e10032 - PMID: 20386609 - PMCID: PMC2850367 - DOI: 10.1371/journal.pone.0010032

Berny MA, Munnix IC, Auger JM, Schols SE, Cosemans JM, Panizzi P, Bock PE, Watson SP, McCarty OJ, Heemskerk JW

Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear. PLoS ONE. 2010;5(4):e10415 - PMID: 20454680 - PMCID: PMC2861630 - DOI: 10.1371/journal.pone.0010415

Gibert Y, Lattanzi VJ, Zhen AW, Vedder L, Brunet F, Faasse SA, Babitt JL, Lin HY, Hammerschmidt M, Fraenkel PG

BMP Signaling Modulates Hepcidin Expression in Zebrafish Embryos Independent of Hemojuvelin. PLoS ONE. 2011;6(1):e14553 - PMID: 21283739 - PMCID: PMC3024971 - DOI: 10.1371/journal.pone.0014553

Thurber GM, Weissleder R

A Systems Approach for Tumor Pharmacokinetics PLoS ONE. 2011;6(9):e24696 - PMID: 21935441 - PMCID: PMC3173470 - DOI: 10.1371/journal.pone.0024696

Settles M, Etzrodt M, Kosanke K, Schiemann M, Zimmermann A, Meier R, Braren R, Huber A, Rummeny EJ, Weissleder R, Swirski FK, Wildgruber M

Different capacity of monocyte subsets to phagocytose iron-oxide nanoparticles. PLoS ONE. 2011;6(10):e25197 - PMID: 21984904 - PMCID: PMC3184946 - DOI: 10.1371/journal.pone.0025197

Ryan RJ, Nitta M, Borger D, Zukerberg LR, Ferry JA, Harris NL, Iafrate AJ, Bernstein BE, Sohani AR, Le LP

EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas. PLoS ONE. 2011;6(12):e28585 - PMID: 22194861 - PMCID: PMC3237460 - DOI: 10.1371/journal.pone.0028585

Rice WL, Zhang Y, Chen Y, Matsuzaki T, Brown D, Lu HA

Differential, Phosphorylation Dependent Trafficking of AQP2 in LLC-PK1 Cells. PLoS ONE. 2012;7(2):e32843 - PMID: 22403603 - PMCID: PMC3293519 - DOI: 10.1371/journal.pone.0032843

Atkinson W*, Forghani R*, Wojtkiewicz GR, Pulli B, Iwamoto Y, Ueno T, Waterman P, Truelove J, Oklu R, Chen JW

Ligation of the Jugular Veins Does Not Result in Brain Inflammation or Demyelination in Mice PLoS ONE. 2012;7(3):e33671 - PMID: 22457780 - PMCID: PMC3310075 - DOI: 10.1371/journal.pone.0033671

Vinegoni C, Feruglio PF, Razansky D, Gorbatov R, Ntziachristos V, Sbarbati A, Nahrendorf M, Weissleder R

Mapping molecular agents distributions in whole mice hearts using born-normalized optical projection tomography. PLoS ONE. 2012;7(4):e34427 - PMID: 22509302 - PMCID: PMC3324534 - DOI: 10.1371/journal.pone.0034427

Staropoli JF, Haliw L, Biswas S, Garrett L, Hölter SM, Becker L, Skosyrski S, Da Silva-Buttkus P, Calzada-Wack J, Neff F, Rathkolb B, Rozman J, Schrewe A, Adler T, Puk O, Sun M, Favor J, Racz I, Bekeredjian R, Busch DH, Graw J, Klingenspor M, Klopstock T, Wolf E, Wurst W, Zimmer A, Lopez E, Harati H, Hill E, Krause DS, Guide J, Dragileva E, Gale E, Wheeler VC, Boustany RM, Brown DE, Breton S, Ruether K, Gailus-Durner V, Fuchs H, de Angelis MH, Cotman SL

Large-Scale Phenotyping of an Accurate Genetic Mouse Model of JNCL Identifies Novel Early Pathology Outside the Central Nervous System. PLoS ONE. 2012;7(6):e38310 - PMID: 22701626 - PMCID: PMC3368842 - DOI: 10.1371/journal.pone.0038310

Malka R, Shochat E, Rom-Kedar V

Bistability and bacterial infections. PLoS ONE. 2010;5(5):e10010 - PMID: 20463954 - PMCID: PMC2864736 - DOI: 10.1371/journal.pone.0010010

Chong NW, Koekemoer AL, Ounzain S, Samani NJ, Shin JT, Shaw SY

STARS Is Essential to Maintain Cardiac Development and Function In Vivo via a SRF Pathway. PLoS ONE. 2012;7(7):e40966 - PMID: 22815879 - PMCID: PMC3399798 - DOI: 10.1371/journal.pone.0040966

Wu Q, Sun CC, Lin HY, Babitt JL

Repulsive Guidance Molecule (RGM) Family Proteins Exhibit Differential Binding Kinetics for Bone Morphogenetic Proteins (BMPs). PLoS ONE. 2012;7(9):e46307 - PMID: 23029472 - PMCID: PMC3459908 - DOI: 10.1371/journal.pone.0046307

Păunescu TG, Rodriguez S, Benz E, McKee M, Tyszkowski R, Albers MW, Brown D

Loss of the V-ATPase B1 Subunit Isoform Expressed in Non-Neuronal Cells of the Mouse Olfactory Epithelium Impairs Olfactory Function. PLoS ONE. 2012;7(9):e45395 - PMID: 23028982 - PMCID: PMC3447883 - DOI: 10.1371/journal.pone.0045395

Wu X, Yung LM, Cheng WH, Yu PB, Babitt JL, Lin HY, Xia Y

Hepcidin Regulation by BMP Signaling in Macrophages Is Lipopolysaccharide Dependent. PLoS ONE. 2012;7(9):e44622 - PMID: 23028567 - PMCID: PMC3441567 - DOI: 10.1371/journal.pone.0044622

Rice WL, Van Hoek AN, Păunescu TG, Huynh C, Goetze B, Singh B, Scipioni L, Stern LA, Brown D

High resolution helium ion scanning microscopy of the rat kidney. PLoS ONE. 2013;8(3):e57051 - PMID: 23505418 - PMCID: PMC3591388 - DOI: 10.1371/journal.pone.0057051

Buys ES, Ko YC, Alt C, Hayton SR, Jones A, Tainsh LT, Ren R, Giani A, Clerté M, Abernathy E, Tainsh RE, Oh DJ, Malhotra R, Arora P, de Waard N, Yu B, Turcotte R, Nathan D, Scherrer-Crosbie M, Loomis SJ, Kang JH, Lin CP, Gong H, Rhee DJ, Brouckaert P, Wiggs JL, Gregory MS, Pasquale LR, Bloch KD, Ksander BR

Soluble Guanylate Cyclase α1-Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma. PLoS ONE. 2013;8(3):e60156 - PMID: 23527308 - PMCID: PMC3603933 - DOI: 10.1371/journal.pone.0060156

Giedt RJ, Koch PD, Weissleder R

Single Cell Analysis of Drug Distribution by Intravital Imaging. PLoS ONE. 2013;8(4):e60988 - PMID: 23593370 - PMCID: PMC3622689 - DOI: 10.1371/journal.pone.0060988

Prabhakar S, Goto J, Zuang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO

Stochastic model of tsc1 lesions in mouse brain. PLoS ONE. 2013;8(5):e64224 - PMID: 23696872 - PMCID: PMC3655945 - DOI: 10.1371/journal.pone.0064224

Feijó Delgado F, Cermak N, Hecht VC, Son S, Li Y, Knudsen SM, Olcum S, Higgins JM, Chen J, Grover WH, Manalis SR

Intracellular Water Exchange for Measuring the Dry Mass, Water Mass and Changes in Chemical Composition of Living Cells. PLoS ONE. 2013;8(7):e67590 - PMID: 23844039 - PMCID: PMC3699654 - DOI: 10.1371/journal.pone.0067590

Pulli B, Ali M, Forghani R, Schob S, Hsieh KL, Wojtkiewicz G, Linnoila JJ, Chen JW

Measuring myeloperoxidase activity in biological samples. PLoS ONE. 2013;8(7):e67976 - PMID: 23861842 - PMCID: PMC3702519 - DOI: 10.1371/journal.pone.0067976

Carlson AL, Fujisaki J, Wu J, Runnels JM, Turcotte R, Spencer JA, Celso CL, Scadden DT, Strom TB, Lin CP

Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label. PLoS ONE. 2013;8(8):e69257 - PMID: 23990881 - PMCID: PMC3753322 - DOI: 10.1371/journal.pone.0069257

Mortensen LJ, Levy O, Phillips JP, Stratton T, Triana B, Ruiz JP, Gu F, Karp JM, Lin CP

Quantification of Mesenchymal Stem Cell (MSC) Delivery to a Target Site Using In Vivo Confocal Microscopy. PLoS ONE. 2013;8(10):e78145 - PMID: 24205131 - PMCID: PMC3812161 - DOI: 10.1371/journal.pone.0078145

Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL

Modeling disease severity in multiple sclerosis using electronic health records. PLoS ONE. 2013;8(11):e78927 - PMID: 24244385 - PMCID: PMC3823928 - DOI: 10.1371/journal.pone.0078927

Kim E, Yang K, Weissleder R

Bioorthogonal Small Molecule Imaging Agents Allow Single-Cell Imaging of MET PLoS ONE. 2013;8 (11):e81275 - PMID: 24265843 - PMCID: PMC3827223 - DOI: 10.1371/journal.pone.0081275

Meynard D, Sun CC, Wu Q, Chen W, Chen S, Nelson CN, Waters MJ, Babitt JL, Lin HY

Inflammation Regulates TMPRSS6 Expression via STAT5. PLoS ONE. 2013;8(12):e82127 - PMID: 24376517 - PMCID: PMC3871639 - DOI: 10.1371/journal.pone.0082127

Elman JS, Murray RM, Wang F, Shen K, Gao S, Conway KE, Yarmush ML, Tannous BA, Weissleder R, Parekkadan B

Pharmacokinetics of natural and engineered secreted factors delivered by mesenchymal stromal cells. PLoS ONE. 2014;9(2):e89882 - PMID: 24587097 - PMCID: PMC3931832 - DOI: 10.1371/journal.pone.0089882

Miranda KC, Bond DT, Levin JZ, Adiconis X, Sivachenko A, Russ C, Brown D, Nusbaum C, Russo LM

Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. PLoS ONE. 2014;9(5):e96094 - PMID: 24816817 - PMCID: PMC4015934 - DOI: 10.1371/journal.pone.0096094

Mehan WA, González RG, Buchbinder BR, Chen JW, Copen WA, Gupta R, Hirsch JA, Hunter GJ, Hunter S, Johnson JM, Kelly HR, Larvie M, Lev MH, Pomerantz SR, Rapalino O, Rincon S, Romero JM, Schaefer PW, Shah V

Optimal Brain MRI Protocol for New Neurological Complaint. PLoS ONE. 2014;9(10):e110803 - PMID: 25343371 - PMCID: PMC4208779 - DOI: 10.1371/journal.pone.0110803

Hsieh LC, Chen JW, Wang LY, Tsang YM, Shueng PW, Liao LJ, Lo WC, Lin YC, Tseng CF, Kuo YS, Jhuang JY, Tien HJ, Juan HF, Hsieh CH

Predicting the severity and prognosis of trismus after intensity-modulated radiation therapy for oral cancer patients by magnetic resonance imaging. PLoS ONE. 2014;9(3):e92561 - PMID: 24658376 - PMCID: PMC3962418 - DOI: 10.1371/journal.pone.0092561

Kessinger CW, Kim JW, Henke PK, Thompson B, McCarthy JR, Hara T, Sillesen M, Margey RJ, Libby P, Weissleder R, Lin CP, Jaffer FA

Statins Improve the Resolution of Established Murine Venous Thrombosis: Reductions in Thrombus Burden and Vein Wall Scarring. PLoS ONE. 2015;10(2):e0116621 - PMID: 25680183 - PMCID: PMC4334538 - DOI: 10.1371/journal.pone.0116621

Azroyan A, Cortez-Retamozo V, Bouley R, Liberman R, Ruan YC, Kiselev E, Jacobson KA, Pittet MJ, Brown D, Breton S

Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor. PLoS ONE. 2015;10(3):e0121419 - PMID: 25799465 - PMCID: PMC4370445 - DOI: 10.1371/journal.pone.0121419

Rotem A, Ram O, Shoresh N, Sperling RA, Schnall-Levin M, Zhang H, Basu A, Bernstein BE, Weitz DA

High-Throughput Single-Cell Labeling (Hi-SCL) for RNA-Seq Using Drop-Based Microfluidics. PLoS ONE. 2015;10(5):e0116328 - PMID: 26000628 - PMCID: PMC4441486 - DOI: 10.1371/journal.pone.0116328

Abazari A, Meimetis LG, Budin G, Bale SS, Weissleder R, Toner M

Engineered Trehalose Permeable to Mammalian Cells. PLoS ONE. 2015;10(6):e0130323 - PMID: 26115179 - PMCID: PMC4482662 - DOI: 10.1371/journal.pone.0130323

Chung HJ, Pellegrini KL, Chung J, Wanigasuriya K, Jayawardene I, Lee K, Lee H, Vaidya VS, Weissleder R

Nanoparticle Detection of Urinary Markers for Point-of-Care Diagnosis of Kidney Injury. PLoS ONE. 2015;10(7):e0133417 - PMID: 26186708 - PMCID: PMC4506142 - DOI: 10.1371/journal.pone.0133417

Liao KP, Ananthakrishnan AN, Kumar V, Xia Z, Cagan A, Gainer VS, Goryachev S, Chen P, Savova GK, Agniel D, Churchill S, Lee J, Murphy SN, Plenge RM, Szolovits P, Kohane I, Shaw SY, Karlson EW, Cai T

Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts. PLoS ONE. 2015;10(8):e0136651 - PMID: 26301417 - PMCID: PMC4547801 - DOI: 10.1371/journal.pone.0136651

Rice WL, Li W, Mamuya F, McKee M, Păunescu TG, Lu HA

Polarized Trafficking of AQP2 Revealed in Three Dimensional Epithelial Culture. PLoS ONE. 2015;10(7):e0131719 - PMID: 26147297 - PMCID: PMC4493001 - DOI: 10.1371/journal.pone.0131719

Sosulski A, Horn H, Zhang L, Coletti C, Vathipadiekal V, Castro CM, Birrer MJ, Nagano O, Saya H, Lage K, Donahoe PK, Pépin D

CD44 Splice Variant v8-10 as a Marker of Serous Ovarian Cancer Prognosis. PLoS ONE. 2016;11(6):e0156595 - PMID: 27253518 - PMCID: PMC4890777 - DOI: 10.1371/journal.pone.0156595

Vafai SB, Mevers E, Higgins KW, Fomina Y, Zhang J, Mandinova A, Newman D, Shaw SY, Clardy J, Mootha VK

Natural Product Screening Reveals Naphthoquinone Complex I Bypass Factors. PLoS ONE. 2016;11(9):e0162686 - PMID: 27622560 - PMCID: PMC5021346 - DOI: 10.1371/journal.pone.0162686

Miller MA, Feng XJ, Li G, Rabitz HA

Identifying biological network structure, predicting network behavior, and classifying network state with High Dimensional Model Representation (HDMR). PLoS ONE. 2012;7(6):e37664 - PMID: 22723838 - PMCID: PMC3377689 - DOI: 10.1371/journal.pone.0037664

Tokarz D, Cisek R, Wein MN, Turcotte R, Haase C, Yeh SA, Bharadwaj S, Raphael AP, Paudel H, Alt C, Liu TM, Kronenberg HM, Lin CP

Intravital imaging of osteocytes in mouse calvaria using third harmonic generation microscopy. PLoS ONE. 2017;12(10):e0186846 - PMID: 29065178 - PMCID: PMC5655444 - DOI: 10.1371/journal.pone.0186846

Arystarkhova E, Bouley R, Liu YB, Sweadner KJ

Impaired AQP2 trafficking in Fxyd1 knockout mice: A role for FXYD1 in regulated vesicular transport. PLoS ONE. 2017;12(11):e0188006 - PMID: 29155857 - PMCID: PMC5695786 - DOI: 10.1371/journal.pone.0188006

Sahin A, Sanchez C, Bullain S, Waterman P, Weissleder R, Carter BS

Development of third generation anti-EGFRvIII chimeric T cells and EGFRvIII-expressing artificial antigen presenting cells for adoptive cell therapy for glioma. PLoS ONE. 2018;13(7):e0199414 - PMID: 29975720 - PMCID: PMC6033533 - DOI: 10.1371/journal.pone.0199414

Nair AV, Yanhong W, Paunescu TG, Bouley R, Brown D

Sex-dependent differences in water homeostasis in wild-type and V-ATPase B1-subunit deficient mice. PLoS ONE. 2019;14(8):e0219940 - PMID: 31386675 - PMCID: PMC6684071 - DOI: 10.1371/journal.pone.0219940

Chin LY, Carroll C, Raigani S, Detelich DM, Tessier SN, Wojtkiewicz GR, Schmidt SP, Weissleder R, Yeh H, Uygun K, Parekkadan B

Ex vivo perfusion-based engraftment of genetically engineered cell sensors into transplantable organs. PLoS ONE. 2019;14(12):e0225222 - PMID: 31790444 - PMCID: PMC6886851 - DOI: 10.1371/journal.pone.0225222

Peng S, Wang JW, Karanam B, Wang C, Huh WK, Alvarez RD, Pai SI, Hung CF, Wu TC, Roden RB

Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer. PLoS ONE. 2015;10(1):e116389 - PMID: 25560237 - PMCID: PMC4283968 - DOI: 10.1371/journal.pone.0116389

Wu JW, Jung Y, Yeh SA, Seo Y, Runnels JM, Burns CS, Mizoguchi T, Ito K, Spencer JA, Lin CP

Intravital fluorescence microscopy with negative contrast. PLoS ONE. 2021;16(8):e0255204 - PMID: 34351959 - PMCID: PMC8341626 - DOI: 10.1371/journal.pone.0255204

Leming M, Das S, Im H

Adversarial confound regression and uncertainty measurements to classify heterogeneous clinical MRI in Mass General Brigham. PLoS ONE. 2023;18(3):e0277572 - PMID: 36862751 - PMCID: PMC9980829 - DOI: 10.1371/journal.pone.0277572

Yoon BC, Pomerantz SR, Mercaldo ND, Goyal S, L'Italien EM, Lev MH, Buch KA, Buchbinder BR, Chen JW, Conklin J, Gupta R, Hunter GJ, Kamalian SC, Kelly HR, Rapalino O, Rincon SP, Romero JM, He J, Schaefer PW, Do S, González RG

Incorporating algorithmic uncertainty into a clinical machine deep learning algorithm for urgent head CTs. PLoS ONE. 2023;18(3):e0281900 - PMID: 36913348 - PMCID: PMC10010506 - DOI: 10.1371/journal.pone.0281900

Lee SE, Jeong SE, Hong JS, Im H, Hwang SY, Oh JK, Kim SE

Gold-Nanoparticle-Coated Magnetic Beads for ALP-Enzyme-Based Electrochemical Immunosensing in Human Plasma. Materials (Basel). 2022;15(19):ePub - PMID: 36234217 - PMCID: PMC9573121 - DOI: 10.3390/ma15196875

Stone JH, Khosroshahi A, Deshpande V, Stone JR

IgG4-related systemic disease accounts for a significant proportion of thoracic lymphoplasmacytic aortitis cases. Arthritis Care Res. 2010;62(3):316-22 - PMID: 20391477 - DOI: 10.1002/acr.20095

Unizony S, Arias-Urdaneta L, Miloslavsky E, Arvikar S, Khosroshahi A, Keroack B, Stone J, Stone J

Tocilizumab for the treatment of large-vessel vasculitis (giant cell arteritis, takayasu arteritis) and polymyalgia rheumatica. Arthritis Care Res (Hoboken). 2012;64(11):1720-9 - PMID: 22674883 - DOI: 10.1002/acr.21750

Liao KP, Cai T, Gainer VS, Cagan A, Murphy SN, Liu C, Churchill S, Shaw SY, Kohane I, Solomon DH, Plenge RM, Karlson EW

Lipid and lipoprotein levels and trends in rheumatoid arthritis compared to the general population. Arthritis Care Res (Hoboken). 2013;65(12):2046-50 - PMID: 23925980 - PMCID: PMC4060244 - DOI: 10.1002/acr.22091

Da Silva N, Shum WW, El-Annan J, Paunescu TG, McKee M, Smith PJ, Brown D, Breton S

Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit. Am J Physiol Cell Physiol. 2007;293(1):C199-210 - PMID: 17392376 - DOI: 10.1152/ajpcell.00596.2006

Pastor-Soler NM, Hallows KR, Smolak C, Gong F, Brown D, Breton S

Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells. Am J Physiol Cell Physiol. 2008;294:C488-94 - PMID: 18160485 - PMCID: PMC4303256 - DOI: 10.1152/ajpcell.00537.2007

Roelen B, Cohen O, Raychowdhury M, Chadee D, Zhang Y, Kyriakis J, Alessandrini A, Lin H

Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation. Am J Physiol Cell Physiol. 2003;285(4):C823-30 - PMID: 12801888 - DOI: 10.1152/ajpcell.00053.2003

Paunescu TG, Jones AC, Tyszkowski R, Brown D

V-ATPase expression in the mouse olfactory epithelium. Am J Physiol Cell Physiol. 2008;295(4):C923-30 - PMID: 18667600 - PMCID: PMC2575830 - DOI: 10.1152/ajpcell.00237.2008

Nunes P, Hasler U, McKee M, Lu HA, Bouley R, Brown D

A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2 (AQP2). Am J Physiol Cell Physiol. 2008;295(6):C1476-87 - PMID: 18799651 - PMCID: PMC2603565 - DOI: 10.1152/ajpcell.00344.2008

Belleannee C, Da Silva N, Shum WW, Brown D, Breton S

Role of purinergic signaling pathways in V-ATPase recruitment to the apical membrane of acidifying epididymal clear cells. Am J Physiol Cell Physiol. 2010;298(4):C817-30 - PMID: 20071692 - PMCID: PMC2853219 - DOI: 10.1152/ajpcell.00460.2009

Da Silva N, Pisitkun T, Belleannee C, Miller LR, Nelson RD, Knepper MA, Brown D, Breton S

Proteomic analysis of V-ATPase-rich cells harvested from the kidney and epididymis by fluorescence activated cell sorting. Am J Physiol Cell Physiol. 2010;298(6):C1326-42 - PMID: 20181927 - PMCID: PMC2889637 - DOI: 10.1152/ajpcell.00552.2009

Miller RL, Zhang P, Smith M, Beaulieu V, Paunescu TG, Brown D, Breton S, Nelson RD

V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice. Am J Physiol Cell Physiol. 2005;288(5):C1134-44 - PMID: 15634743 - DOI: 10.1152/ajpcell.00084.2004

Paunescu TG, Da Silva N, Marshansky V, McKee M, Breton S, Brown D

Expression of the 56-kDa B2 subunit isoform of the vacuolar H(+)-ATPase in proton-secreting cells of the kidney and epididymis. Am J Physiol Cell Physiol. 2004;287(1):C149-62 - PMID: 15013950 - DOI: 10.1152/ajpcell.00464.2003

Paunescu TG, Blazer-Yost BL, Vlahos CJ, Helman SI

LY-294002-inhibitable PI 3-kinase and regulation of baseline rates of Na(+) transport in A6 epithelia. Am J Physiol Cell Physiol. 2000;279(1):C236-47 - PMID: 10898735 - DOI: 10.1152/ajpcell.2000.279.1.C236

Merkulova M, Hurtado-Lorenzo A, Hosokawa H, Zhuang Z, Brown D, Ausiello DA, Marshansky V

Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution. Am J Physiol Cell Physiol. 2011;300(6):C1442-55 - PMID: 21307348 - PMCID: PMC3118619 - DOI: 10.1152/ajpcell.00076.2010

Shum WW, Da Silva N, Belleannee C, McKee M, Brown D, Breton S

Regulation of V-ATPase recycling via a RhoA and ROCKII dependent pathway in epididymal clear cells. Am J Physiol Cell Physiol. 2011;301(1):C31-43 - PMID: 21411727 - PMCID: PMC3129830 - DOI: 10.1152/ajpcell.00198.2010

Stevens AL, Breton S, Gustafson CE, Bouley R, Nelson RD, Kohan DE, Brown D

Aquaporin 2 is a vasopressin-independent, constitutive apical membrane protein in rat vas deferens. Am J Physiol Cell Physiol. 2000;278(4):C791-802 - PMID: 10751327 - DOI: 10.1152/ajpcell.2000.278.4.C791

Isnard-Bagnis C, Da Silva N, Beaulieu V, Yu AS, Brown D, Breton S

Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM. Am J Physiol Cell Physiol. 2003;284(1):C220-32 - PMID: 12475763 - DOI: 10.1152/ajpcell.00374.2001

El-Annan J, Brown D, Breton S, Bourgoin S, Ausiello DA, Marshansky V

Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ. Am J Physiol Cell Physiol. 2003;286(4):C768-78 - PMID: 14684384 - DOI: 10.1152/ajpcell.00250.2003

Winter C, Kampik NB, Vedovelli L, Rothenberger F, Paunescu TG, Stehberger PA, Brown D, John H, Wagner CA

Aldosterone stimulates vacuolar H+-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C dependent pathway. Am J Physiol Cell Physiol. 2011;301(5):C1251-61 - PMID: 21832245 - PMCID: PMC3213922 - DOI: 10.1152/ajpcell.00076.2011

Bouley R, Lin HY, Raychowdhury MK, Marshansky V, Brown D, Ausiello DA

Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway. Am J Physiol Cell Physiol. 2005;288(6):C1390-401 - PMID: 15677378 - DOI: 10.1152/ajpcell.00353.2004

Pitsillides CM, Runnels JM, Spencer JA, Zhi L, Wu MX, Lin CP

Cell labeling approaches for fluorescence-based in vivo flow cytometry. Cytometry A. 2011;79(10):758-65 - PMID: 21905206 - PMCID: PMC3686107 - DOI: 10.1002/cyto.a.21125

Lisi S, Botta R, Pinchera A, Collins AB, Refetoff S, Arvan P, Bu G, Grasso L, Marshansky V, Bechoua S, Hurtado-Lorenzo A, Marcocci C, Brown D, McCluskey RT, Marinò M

Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice. Am J Physiol Cell Physiol. 2005;290(4):C1160-7 - PMID: 16306127 - DOI: 10.1152/ajpcell.00382.2005

Zhang L, Alt C, Li P, White RM, Zon LI, Wei X, Lin CP

An optical platform for cell tracking in adult zebrafish. Cytometry A. 2011;81(2):176-82 - PMID: 22162445 - PMCID: PMC6383206 - DOI: 10.1002/cyto.a.21167

Brown D, Bouley R, Paunescu TG, Breton S, Lu HA

New insights into the dynamic regulation of water and acid/base balance by renal epithelial cells. Am J Physiol Cell Physiol. 2012;302(10):C1421-33 - PMID: 22460710 - PMCID: PMC3362000 - DOI: 10.1152/ajpcell.00085.2012

Yui N, Lu HA, Chen Y, Nomura N, Bouley R, Brown D

Basolateral targeting and microtubule dependent transcytosis of the aquaporin-2 water channel. Am J Physiol Cell Physiol. 2012;304(1):C38-48 - PMID: 23015545 - PMCID: PMC3543574 - DOI: 10.1152/ajpcell.00109.2012

Roy JW, Hill E, Ruan YC, Vedovelli L, Paunescu T, Brown D, Breton S

Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis. Am J Physiol Cell Physiol. 2013;305(4):C436-46 - PMID: 23761626 - PMCID: PMC3891217 - DOI: 10.1152/ajpcell.00410.2012

Schonbrun E, Malka R, Di Caprio G, Schaak D, Higgins JM

Quantitative absorption cytometry for measuring red blood cell hemoglobin mass and volume. Cytometry A. 2014;85(4):332-8 - PMID: 24677669 - PMCID: PMC4717472 - DOI: 10.1002/cyto.a.22450

Nomura N, Nunes P, Bouley R, Nair AV, Shaw S, Ueda E, Pathomthongtaweechai N, Lu HA, Brown D

High throughput chemical screening identifies AG-490 as a stimulator of aquaporin 2 membrane expression and urine concentration. Am J Physiol Cell Physiol. 2014;307(7):C597-605 - PMID: 24944200 - PMCID: PMC4187055 - DOI: 10.1152/ajpcell.00154.2014

Zuk A, Bonventre JV, Brown D, Matlin KS

Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney. Am J Physiol Cell Physiol. 1998;275(3):C711-C731 - PMID: 29585718 - DOI: 10.1152/ajpcell.1998.275.3.C711

Breton S, Hammar K, Smith PJS, Brown D

Proton secretion in the male reproductive tract: involvement of Cl--independent HCO 3 - transport. Am J Physiol Cell Physiol. 1998;275(4):C1134-C1142 - PMID: 29585324 - DOI: 10.1152/ajpcell.1998.275.4.C1134

Li R, Attari A, Prytyskach M, Garlin MA, Weissleder R, Miller MA

Single‐Cell Intravital Microscopy of Trastuzumab Quantifies Heterogeneous in vivo Kinetics Cytometry A. 2019;97(5):528-539 - PMID: 31423731 - PMCID: PMC7028488 - DOI: 10.1002/cyto.a.23872

Shon SM, Park JH, Nahrendorf M, Schellingerhout D, Kim JY, Kang BT, Jeong SW, Kim EJ, Ryu JH, Kim K, Kwon IC, Lee DK, Lee MM, Kim DE

Exercise attenuates matrix metalloproteinase activity in preexisting atherosclerotic plaque. Atherosclerosis. 2011;216(1):67-73 - PMID: 21334624 - DOI: 10.1016/j.atherosclerosis.2011.01.036

Cheng S, Wang N, Larson MG, Palmisano JN, Mitchell GF, Benjamin EJ, Vasan RS, Levy D, McCabe EL, Vita JA, Wang TJ, Shaw SY, Cohen KS, Hamburg NM

Circulating angiogenic cell populations, vascular function, and arterial stiffness. Atherosclerosis. 2011;220(1):145-50 - PMID: 22093724 - PMCID: PMC3277804 - DOI: 10.1016/j.atherosclerosis.2011.10.015

Ge Y, Cheng S, Larson MG, Ghorbani A, Martin RP, Klein RJ, O'Donnell CJ, Vasan RS, Shaw SY, Wang TJ, Cohen KS

Circulating CD31+ leukocyte frequency is associated with cardiovascular risk factors. Atherosclerosis. 2013;229(1):228-233 - PMID: 23701996 - PMCID: PMC3984590 - DOI: 10.1016/j.atherosclerosis.2013.04.017

Hink M, Shah K, Russinova E, de Vries S, Visser A

Fluorescence Fluctuation Analysis of AtSERK and BRI1 Oligomerization. Biophys J. 2007;94(3):1052-62 - PMID: 17905839 - PMCID: PMC2186235 - DOI: 10.1529/biophysj.107.112003

Pitsillides C, Joe E, Wei X, Anderson R, Lin C

Selective cell targeting with light-absorbing microparticles and nanoparticles. Biophys J. 2003;84:4023-32 - PMID: 12770906 - PMCID: PMC1302982 - DOI: 10.1016/S0006-3495(03)75128-5

Paunescu TG, Helman SI

PGE(2) activation of apical membrane Cl(-) channels in A6 epithelia: impedance analysis. Biophys J. 2001;81(2):852-66 - PMID: 11463630 - PMCID: PMC1301558 - DOI: 10.1016/S0006-3495(01)75746-3

Paunescu TG, Helman SI

cAmp activation of apical membrane Cl(-) channels: theoretical considerations for impedance analysis. Biophys J. 2001;81(2):838-51 - PMID: 11463629 - PMCID: PMC1301557 - DOI: 10.1016/S0006-3495(01)75745-1

Chow MJ, Turcotte R, Lin CP, Zhang Y

Arterial Extracellular Matrix: A Mechanobiological Study of the Contributions and Interactions of Elastin and Collagen. Biophys J. 2014;106(12):2684-2692 - PMID: 24940786 - PMCID: PMC4070071 - DOI: 10.1016/j.bpj.2014.05.014

Lu X, Wood DK, Higgins JM

Deoxygenation Reduces Sickle Cell Blood Flow at Arterial Oxygen Tension. Biophys J. 2016;110(12):2751-8 - PMID: 27332133 - PMCID: PMC4919586 - DOI: 10.1016/j.bpj.2016.04.050

Turcotte R, Mattson JM, Wu JW, Zhang Y, Lin CP

Molecular Order of Arterial Collagen Using Circular Polarization Second-Harmonic Generation Imaging. Biophys J. 2016;110(3):530-3 - PMID: 26806883 - PMCID: PMC4744203 - DOI: 10.1016/j.bpj.2015.12.030

Qi Y, Reyes A, Johnstone SE, Aryee MJ, Bernstein BE, Zhang B

Data-Driven Polymer Model for Mechanistic Exploration of Diploid Genome Organization. Biophys J. 2020;119(9):1905-1916 - PMID: 33086041 - PMCID: PMC7677132 - DOI: 10.1016/j.bpj.2020.09.009

Song TH, Cao M, Min J, Im H, Lee H, Lee K

Deep learning-based phenotyping of breast cancer cells using lens-free digital in-line holography. Biophys J. 2023;122(3S1):285a - PMID: 36783413 - DOI: 10.1016/j.bpj.2022.11.1619

Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT, Weissleder R

A Novel Method of Imaging Calcium Urolithiasis Using Fluorescence. J Urolology. 2008;179:1610-1614 - PMID: 18295253 - DOI: 10.1016/j.juro.2007.11.100

Perazzo A, Peng Z, Young YN, Feng Z, Wood DK, Higgins JM, Stone HA

The effect of rigid cells on blood viscosity: linking rheology and sickle cell anemia. Soft Matter. 2022;18(3):554-565 - PMID: 34931640 - PMCID: PMC8925304 - DOI: 10.1039/d1sm01299a

Da Silva N, Barton CR

Macrophages and dendritic cells in the post-testicular environment. Cell Tissue Res. 2015;363(1):97-104 - PMID: 26337514 - PMCID: PMC4703462 - DOI: 10.1007/s00441-015-2270-0

Menezes TP, Hill E, de Alencar Moura A, Lobo MDP, Monteiro-Moreira ACO, Breton S, Machado-Neves M

Pattern of protein expression in the epididymis of Oligoryzomys nigripes (Cricetidae, Sigmodontinae). Cell Tissue Res. 2017;372(1):135-147 - PMID: 29119327 - DOI: 10.1007/s00441-017-2714-9

Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, Snyder EY

Neural stem cell biology may be well suited for improving brain tumor therapies Cancer J. 2003;9:189-204 - PMID: 12952304 - DOI: 10.1097/00130404-200305000-00007

Funovics M, Weissleder R, Tung CH

Protease sensors for bioimaging Anal Bioanal Chem. 2003;377:956-63 - PMID: 12955390 - DOI: 10.1007/s00216-003-2199-0

Reynolds F, O'loughlin T, Weissleder R, Josephson L.

Method of Determining Nanoparticle Core Weight Anal Bioanal Chem. 2005;77(3):814-817 - PMID: 15679348 - DOI: 10.1021/ac049307x

Feldman AS, McDougal WS, Harisinghani MG

The potential of nanoparticle-enhanced imaging. Urol Oncol. 2008;26(1):65-73 - PMID: 18190834 - DOI: 10.1016/j.urolonc.2007.03.016

Huebert D, Kamal M, O'Donovan A, Bernstein B

Genome-wide analysis of histone modifications by ChIP-on-chip. Methods. 2006;40(4):365-9 - PMID: 17101450 - DOI: 10.1016/j.ymeth.2006.07.032

Nahrendorf M, Badea C, Hedlund LW, Figueiredo JL, Sosnovik DE, Johnson GA, Weissleder R

High Resolution Imaging of Murine Myocardial Infarction With Delayed Enhancement Cine Micro-CT. Am J Physiol-Heart C. 2007;292(6):3172-8 - PMID: 17322414 - PMCID: PMC2680216 - DOI: 10.1152/ajpheart.01307.2006

Nahrendorf M, Streif J, Hiller K, Hu K, Nordbeck P, Ritter O, Sosnovik D, Bauer L, Neubauer S, Jakob P, Ertl G, Spindler M, Bauer W

Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics. Am J Physiol-Heart C. 2006;290(6):H2516-21 - PMID: 16415075 - DOI: 10.1152/ajpheart.01038.2005

Nahrendorf M, Hiller K, Greiser A, Kohler S, Neuberger T, Hu K, Waller C, Albrecht M, Neubauer S, Haase A, Ertl G, Bauer W

Chronic coronary artery stenosis induces impaired function of remote myocardium: MRI and spectroscopy study in rat. Am J Physiol-Heart C. 2003;285(6):H2712-21 - PMID: 12933339 - DOI: 10.1152/ajpheart.00233.2003

Nahrendorf M, Hu K, Fraccarollo D, Hiller K, Haase A, Bauer W, Ertl G

Time course of right ventricular remodeling in rats with experimental myocardial infarction. Am J Physiol-Heart C. 2003;284(1):H241-8 - PMID: 12388245 - DOI: 10.1152/ajpheart.00537.2002

Bian Y, Sun M, Silver M, Ho KK, Marchionni MA, Caggiano AO, Stone JR, Amende I, Hampton TG, Morgan JP, Yan X

Neuregulin-1 Attenuated Doxorubicin-Induced Decrease in Cardiac Troponins. Am J Physiol-Heart C. 2009;297(6):H1974-83 - PMID: 19801490 - PMCID: PMC2793128 - DOI: 10.1152/ajpheart.01010.2008

Bouley R, Pastor-Soler N, Cohen O, McLaughlin M, Breton S, Brown D

Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra). Am J Physiol Renal Physiol. 2005;288(6):F1103-12 - PMID: 15644488 - DOI: 10.1152/ajprenal.00337.2004

Yi X, Bouley R, Lin HY, Bechoua S, Sun TX, Del Re E, Shioda T, Raychowdhury MK, Lu HA, Abou-Samra AB, Brown D, Ausiello DA

Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R. Am J Physiol Renal Physiol. 2007;292(5):F1303-13 - PMID: 17287200 - DOI: 10.1152/ajprenal.00441.2005

Paunescu TG, Da Silva N, Russo LM, McKee M, Lu HA, Breton S, Brown D

Association Of Soluble Adenylyl Cyclase (sAC) With The V-ATPase In Renal Epithelial Cells. Am J Physiol Renal Physiol. 2007;294(1):F130-8 - PMID: 17959750 - DOI: 10.1152/ajprenal.00406.2007

Paunescu TG, Russo LM, Da Silva N, Kovacikova J, Mohebbi N, Van Hoek AN, McKee M, Wagner CA, Breton S, Brown D

Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice. Am J Physiol Renal Physiol. 2007;293(6):F1915-26 - PMID: 17898041 - DOI: 10.1152/ajprenal.00160.2007

Lu HA, Matsuzaki T, Bouley R, Hasler U, Qin Q, Brown D

The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells. Am J Physiol Renal Physiol. 2008;295(1):F290-4 - PMID: 18434387 - PMCID: PMC2494506 - DOI: 10.1152/ajprenal.00072.2008

Van Hoek AN, Bouley R, Lu YX, Silberstein CM, Brown D, Wax MB, Patil RV

Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays. Am J Physiol Renal Physiol. 2009;296(6):F1396-404 - PMID: 19297454 - PMCID: PMC2692439 - DOI: 10.1152/ajprenal.00018.2009

Bouley R, Palomino Z, Tang SS, Nunes P, Kobori H, Lu HA, Shum WW, Sabolic I, Brown D, Ingelfinger JR, Jung FF

Angiotensin II and Hypertonicity Modulate Proximal Tubular Aquaporin 1 (AQP1) Expression. Am J Physiol Renal Physiol. 2009;297(6):F1575-86 - PMID: 19776169 - PMCID: PMC2801332 - DOI: 10.1152/ajprenal.90762.2008

Paunescu TG, Ljubojevic M, Russo LM, Winter C, McLaughlin MM, Wagner CA, Breton S, Brown D

Cyclic AMP stimulates apical V-ATPase accumulation, microvillar elongation and proton extrusion in kidney collecting duct A-intercalated cells. Am J Physiol Renal Physiol. 2010;298(3):F643-54 - PMID: 20053793 - PMCID: PMC2838605 - DOI: 10.1152/ajprenal.00584.2009

Zhuang Z, Marshansky V, Breton S, Brown D

Is caveolin involved in normal proximal tubule (PT) function? Presence in model PT systems but absence in situ. Am J Physiol Renal Physiol. 2010;300(1):F199-206 - PMID: 20980408 - PMCID: PMC3023221 - DOI: 10.1152/ajprenal.00513.2010

Li W, Zhang Y, Bouley R, Chen Y, Matsuzaki T, Nunes P, Hasler U, Brown D, Lu HA

Simvastatin Enhances Aquaporin 2 Surface Expression and Urinary Concentration in Vasopressin Deficient Brattleboro Rats through Modulation of Rho GTPase. Am J Physiol Renal Physiol. 2011;301(2):F309-18 - PMID: 21511701 - PMCID: PMC3154588 - DOI: 10.1152/ajprenal.00001.2011

Breton S, Nsumu NN, Galli T, Sabolic I, Smith PJ, Brown D

Tetanus toxin-mediated cleavage of cellubrevin inhibits proton secretion in the male reproductive tract. Am J Physiol Renal Physiol. 2000;278(5):F717-25 - PMID: 10807583 - DOI: 10.1152/ajprenal.2000.278.5.F717

Silver RB, Breton S, Brown D

Potassium depletion increases proton pump (H(+)-ATPase) activity in intercalated cells of cortical collecting duct. Am J Physiol Renal Physiol. 2000;279(1):F195-202 - PMID: 10894802 - DOI: 10.1152/ajprenal.2000.279.1.F195

Bagnis C, Marshansky V, Breton S, Brown D

Remodeling the cellular profile of collecting ducts by chronic carbonic anhydrase inhibition. Am J Physiol Renal Physiol. 2001;280(3):F437-48 - PMID: 11181405 - DOI: 10.1152/ajprenal.2001.280.3.F437

Bagnis C, Marsolais M, Biemesderfer D, Laprade R, Breton S

Na+/H+-exchange activity and immunolocalization of NHE3 in rat epididymis. Am J Physiol Renal Physiol. 2001;280(3):F426-36 - PMID: 11181404 - DOI: 10.1152/ajprenal.2001.280.3.F426

Breton S, Inoue T, Knepper MA, Brown D

Antigen retrieval reveals widespread basolateral expression of syntaxin 3 in renal epithelia. Am J Physiol Renal Physiol. 2002;282(3):F523-9 - PMID: 11832435 - DOI: 10.1152/ajprenal.00128.2001

Zharkikh L, Zhu X, Stricklett PK, Kohan DE, Chipman G, Breton S, Brown D, Nelson RD

Renal principal cell-specific expression of green fluorescent protein in transgenic mice. Am J Physiol Renal Physiol. 2002;283(6):F1351-64 - PMID: 12426236 - DOI: 10.1152/ajprenal.0224.2001

Breton S, Brown D

New insights into the regulation of V-ATPase-dependent proton secretion. Am J Physiol Renal Physiol. 2006;292(1):F1-10 - PMID: 17032935 - DOI: 10.1152/ajprenal.00340.2006

Bouley R, Nunes P, Andriopoulos B, McLaughlin MM, Webber MJ, Lin HY, Babitt JL, Gardella TJ, Ausiello DA, Brown D

Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin. Am J Physiol Renal Physiol. 2012;304(5):F553-64 - PMID: 23235478 - PMCID: PMC3602717 - DOI: 10.1152/ajprenal.00438.2011

Vedovelli L, Rothermel JT, Finberg KE, Wagner CA, Azroyan A, Hill E, Breton S, Brown D, Paunescu TG

Altered V-ATPase expression in renal intercalated cells isolated from B1-subunit deficient mice by fluorescence activated cell sorting. Am J Physiol Renal Physiol. 2012;304(5):F522-32 - PMID: 23269648 - PMCID: PMC3602708 - DOI: 10.1152/ajprenal.00394.2012

Paunescu TG, Lu HA, Russo LM, Pastor-Soler NM, McKee M, McLaughlin MM, Bartlett BE, Breton S, Brown D

Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells. Am J Physiol Renal Physiol. 2013;305(12):F1783-F1795 - PMID: 24133120 - PMCID: PMC3882446 - DOI: 10.1152/ajprenal.00622.2012

Lu H, Sun TX, Bouley R, Blackburn K, McLaughlin M, Brown D

Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2. Am J Physiol Renal Physiol. 2003;286(2):F233-43 - PMID: 14519593 - DOI: 10.1152/ajprenal.00179.2003

Herak-Kramberger CM, Breljak D, Ljubojević M, Matokanovic M, Lovric M, Rogic D, Brzica H, Vrhovac I, Karaica D, Micek V, Ivkovic Dupor J, Brown D, Sabolic I

Sex-dependent expression of water channel AQP1 along the rat nephron. Am J Physiol Renal Physiol. 2015;308(8):F809-21 - PMID: 25656365 - PMCID: PMC4398837 - DOI: 10.1152/ajprenal.00368.2014

Arthur J, Huang J, Nomura N, Jin WW, Li W, Cheng X, Brown D, Lu HJ

Characterization of the putative phosphorylation sites of the AQP2 c-terminus and their role in AQP2 trafficking in LLC-PK1 cells. Am J Physiol Renal Physiol. 2015;309(8):F673-9 - PMID: 26290367 - PMCID: PMC4609919 - DOI: 10.1152/ajprenal.00152.2015

David V, Francis C, Babitt JL

Ironing out the crosstalk between FGF23 and inflammation. Am J Physiol Renal Physiol. 2016;312(1):F1-F8 - PMID: 27582104 - PMCID: PMC5283889 - DOI: 10.1152/ajprenal.00359.2016

Mamuya FA, Cano-Peñalver JL, Li WU, Rodriguez-Puyol D, Rodríguez-Puyol M, Brown D, de Frutos S, Lu HJ

ILK and Cytoskeletal Architecture: An Important Determinant of AQP2 Recycling and Subsequent Entry into the Exocytotic Pathway. Am J Physiol Renal Physiol. 2016;311(6):F1346-F1357 - PMID: 27760768 - PMCID: PMC5210194 - DOI: 10.1152/ajprenal.00336.2016

Cheung PW, Ueberdiek L, Day J, Bouley R, Brown D

Protein phosphatase 2C (PP2C) is responsible for VP-induced dephosphorylation of AQP2 serine 261. Am J Physiol Renal Physiol. 2017;313(2):F404-F413 - PMID: 28381458 - PMCID: PMC5582913 - DOI: 10.1152/ajprenal.00004.2017

Mamuya FA, Xie D, Lei L, Huang M, Tsuji K, Capen DE, Yang B, Weissleder R, Păunescu TG, Lu HJ

Deletion of β-1 integrin in collecting duct principal cells leads to tubular injury and renal medullary fibrosis. Am J Physiol Renal Physiol. 2017;313(4):F1026-F1037 - PMID: 28701310 - PMCID: PMC5668581 - DOI: 10.1152/ajprenal.00038.2017

Alper SL, Stuart-Tilley AK, Biemesderfer D, Shmukler BE, Brown D

Immunolocalization of AE2 anion exchanger in rat kidney. Am J Physiol Renal Physiol. 1997;273(4):F601-F614 - PMID: 29587100 - DOI: 10.1152/ajprenal.1997.273.4.F601

Shayakul C, Kanai Y, Lee WS, Brown D, Rothstein JD, Hediger MA

Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. Am J Physiol Renal Physiol. 1997;273(6):F1023-F1029 - PMID: 29586122 - DOI: 10.1152/ajprenal.1997.273.6.F1023

Kawachi H, Kurihara H, Topham PS, Brown D, Shia MA, Orikasa M, Shimizu F, Salant DJ

Slit diaphragm-reactive nephritogenic MAb 5-1-6 alters expression of ZO-1 in rat podocytes. Am J Physiol Renal Physiol. 1997;273(6):F984-F993 - PMID: 29586119 - DOI: 10.1152/ajprenal.1997.273.6.F984

Brown D, Lee R, Bonventre JV

Redistribution of villin to proximal tubule basolateral membranes after ischemia and reperfusion. Am J Physiol Renal Physiol. 1997;273(6):F1003-F1012 - PMID: 29586118 - DOI: 10.1152/ajprenal.1997.273.6.F1003

Montet X, Rajopadhye M, Weissleder R.

An albumin-activated far-red fluorochrome for in vivo imaging ChemMedChem. 2006;1(1):66-69 - PMID: 16892337 - DOI: 10.1002/cmdc.200500028

Choi YD, McCarthy J, Weissleder R, Tung CH

Conjugation of a Photosensitizer to an Oligoarginine-based Cell-penetrating Peptide Increases the Efficacy of Photodynamic Therapy ChemMedChem. 2006;1(4):458-463 - PMID: 16892381 - DOI: 10.1002/cmdc.200500036

Choi Y, Weissleder R, Tung CH

Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate. ChemMedChem. 2006;1:698-701 - PMID: 16902920 - DOI: 10.1002/cmdc.200600053

McCarthy JR, Weissleder R

Model Systems for Fluorescence and Singlet Oxygen Quenching by Metalloporphyrins. ChemMedChem. 2007;2:360-365 - PMID: 17245681 - DOI: 10.1002/cmdc.200600244

Blazer-Yost BL, Paunescu TG, Helman SI, Lee KD, Vlahos CJ

Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption. Am J Physiol. 1999;277(3 Pt 1):C531-6 - PMID: 10484339 - DOI: 10.1152/ajpcell.1999.277.3.C531

Keliher EJ, Reiner T, Turetsky A, Hilderbrand SA, Weissleder R

High-Yielding, Two-Step (18) F Labeling Strategy for (18) F-PARP1 Inhibitors. ChemMedChem. 2011;6(3):424-7 - PMID: 21360818 - PMCID: PMC3136544 - DOI: 10.1002/cmdc.201000426

Beck JS, Breton S, Laprade R, Giebisch G

Volume regulation and intracellular calcium in the rabbit proximal convoluted tubule. Am J Physiol. 1991;260(6 Pt 2):F861-7 - PMID: 2058707 - DOI: 10.1152/ajprenal.1991.260.6.F861

Beck JS, Breton S, Mairb

Relationship between sodium transport and intracellular ATP in isolated perfused rabbit proximal convoluted tubule. Am J Physiol. 1991;261(4 Pt 2):F634-9 - PMID: 1928376 - DOI: 10.1152/ajprenal.1991.261.4.F634

Beck JS, Breton S, Giebisch G, Laprade R

Potassium conductance regulation by pH during volume regulation in rabbit proximal convoluted tubules. Am J Physiol. 1992;263(3 Pt 2):F453-8 - PMID: 1415573 - DOI: 10.1152/ajprenal.1992.263.3.F453

Breton S, Beck JS, Cardinal J, Giebisch G, Laprade R

Involvement and source of calcium in volume regulatory decrease of collapsed proximal convoluted tubule. Am J Physiol. 1992;263(4 Pt 2):F656-64 - PMID: 1415737 - DOI: 10.1152/ajprenal.1992.263.4.F656

Macri P, Breton S, Beck JS, Cardinal J, Laprade R

Basolateral K+, Cl-, and HCO3- conductances and cell volume regulation in rabbit PCT. Am J Physiol. 1993;264(2 Pt 2):F365-76 - PMID: 8447445 - DOI: 10.1152/ajprenal.1993.264.2.F365

Breton S, Beck JS, Laprade R

cAMP stimulates proximal convoluted tubule Na(+)-K(+)-ATPase activity. Am J Physiol. 1994;266(3 Pt 2):F400-10 - PMID: 8160788 - DOI: 10.1152/ajprenal.1994.266.3.F400

Breton S, Alper SL, Gluck SL, Sly WS, Barker JE, Brown D

Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice. Am J Physiol. 1995;269(6 Pt 2):F761-74 - PMID: 8594870 - DOI: 10.1152/ajprenal.1995.269.6.F761

Breton S, Marsolais M, Laprade R

Hypotonicity increases basolateral taurine permeability in rabbit proximal convoluted tubule. Am J Physiol. 1995;268(4 Pt 2):F595-603 - PMID: 7733316 - DOI: 10.1152/ajprenal.1995.268.4.F595

Breton S, Belachgar F, Marsolais M, Lapointe JY, Laprade R

Inhibition of basolateral potassium conductance by taurine in the proximal convoluted tubule. Am J Physiol. 1996;271(5 Pt 2):F1012-9 - PMID: 8945995 - DOI: 10.1152/ajprenal.1996.271.5.F1012

Breton S, Hammar K, Smith PJ, Brown D

Proton secretion in the male reproductive tract: involvement of Cl--independent HCO-3 transport. Am J Physiol. 1998;275(4 Pt 1):C1134-42 - PMID: 9755067 - DOI: 10.1152/ajpcell.1998.275.4.C1134

Emma F, Breton S, Morrison R, Wright S, Strange K

Effect of cell swelling on membrane and cytoplasmic distribution of pICln. Am J Physiol. 1998;274(6 Pt 1):C1545-51 - PMID: 9696697 - DOI: 10.1152/ajpcell.1998.274.6.C1545

Derbyshire ER, Mazitschek R, Clardy J

Characterization of Plasmodium Liver Stage Inhibition by Halofuginone. ChemMedChem. 2012;7(5):844-9 - PMID: 22438279 - PMCID: PMC3359061 - DOI: 10.1002/cmdc.201200045

Miller MA, Askevold B, Yang KS, Kohler RH, Weissleder R

Platinum Compounds for High-Resolution In Vivo Cancer Imaging. ChemMedChem. 2014;9(6):1131-5 - PMID: 24504646 - PMCID: PMC4037345 - DOI: 10.1002/cmdc.201300502

Keliher EJ, Klubnick JA Reiner T, Mazitschek R, Weissleder R

Efficient Acid-Catalyzed (18) F/(19) F Fluoride Exchange of BODIPY Dyes. ChemMedChem. 2014;9(7):1368-73 - PMID: 24596307 - PMCID: PMC4145401 - DOI: 10.1002/cmdc.201300506

Carrasco MP, Machado M, Gonçalves L, Sharma M, Gut J, Lukens AK, Wirth DF, André V, Duarte MT, Guedes RC, J V A Dos Santos D, Rosenthal PJ, Mazitschek R, Prudêncio M, Moreira R

Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites. ChemMedChem. 2016;11(19):2194-2204 - PMID: 27538856 - DOI: 10.1002/cmdc.201600327

Schleyer K, Halabi EA, Weissleder R

γ-Butyrolactone derivatives of MSA-2 are STING prodrugs ChemMedChem. 2024;19(19):e202400416 - PMID: 38887174 - PMCID: PMC11979874 - DOI: 10.1002/cmdc.202400416

McCarthy JR, Hyland MA, Bruckner C.

Synthesis of indaphyrins: meso-tetraarylsecochlorin-based porphyrinoids containing direct o-phenyl-to-beta-linkages. Org Biomol Chem. 2004;2(10):1484-91

McCarthy JR, Bhaumik J, Merbouh N, Weissleder R

High-yielding syntheses of hydrophilic conjugatable chlorins and bacteriochlorins. Org Biomol Chem. 2009;7(17):3430-6 - PMID: 19675897 - PMCID: PMC2749955 - DOI: 10.1039/b908713c

Mazitschek R, Huwe A, Giannis A

Synthesis and biological evaluation of novel fumagillin and ovalicin analogues. Org Biomol Chem. 2005;3(11):2150-4 - PMID: 15917904 - DOI: 10.1039/b503163j

Ueno T, Kaneko K, Katano H, Sato Y, Mazitschek R, Tanaka K, Hattori S, Irie S, Sata T, Ogawa-Goto K

Expansion of the trans-Golgi network following activated collagen secretion is supported by a coiled-coil microtubule-bundling protein, p180, on the ER. Exp Cell Res. 2009;316(3):329-40 - PMID: 19932094 - DOI: 10.1016/j.yexcr.2009.11.009

Pastor-Soler NM, Fisher JS, Sharpe R, Hill E, Van Hoek A, Brown D, Breton S

Aquaporin 9 expression in the developing rat epididymis is modulated by steroid hormones. Reproduction. 2009;139(3):613-21 - PMID: 19948840 - PMCID: PMC3773695 - DOI: 10.1530/REP-09-0284

Da Silva N, Cortez-Retamozo V, Reinecker HC, Wildgruber M, Hill E, Brown D, Swirski F, Pittet M, Breton S

A dense network of dendritic cells populates the murine epididymis. Reproduction. 2011;141(5):653-63 - PMID: 21310816 - PMCID: PMC3657760 - DOI: 10.1530/REP-10-0493

Shum W, Hill E, Brown D, Breton S

Plasticity of basal cells during postnatal development in the rat epididymis. Reproduction. 2013;146(5):455-469 - PMID: 23960170 - PMCID: PMC4106237 - DOI: 10.1530/REP-12-0510

Reimer P, Bader A, Weissleder R

Application of a stable cell culture assay for the functional assessment of novel MR contrast agents. Eur Radiol. 1997;7(4):527-31 - PMID: 9204333 - DOI: 10.1007/s003300050197

Salthouse C, Hilderbrand S, Weissleder R, Mahmood U

Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008;16 (26):21731-7 - PMID: 19104605 - PMCID: PMC2717740 - DOI: 10.1364/oe.16.021731

Vinegoni C, Bredfeldt J, Marks D, Boppart S

Nonlinear optical contrast enhancement for optical coherence tomography. Opt Express. 2004;12:331-41 - PMID: 19471542 - DOI: 10.1364/opex.12.000331

Lee H, Alt C, Pitsillides CM, Puoris'haag M, Lin CP

In vivo imaging flow cytometer. Opt Express. 2006;14:7789-800 - PMID: 19529148 - PMCID: PMC2801598 - DOI: 10.1364/oe.14.007789

Tsai CC, Vinegoni C, Weissleder R

Diffractionless beam in free space with adiabatic changing refractive index in a single mode tapered slab waveguide. Opt Express. 2009;17(24):21723-31 - PMID: 19997414 - PMCID: PMC2805120 - DOI: 10.1364/OE.17.021723

Vinegoni C, Fexon L, Fumene Feruglio P, Pivovarov M, Figueiredo JL, Nahrendorf M, Pozzo A, Sbarbati A, Weissleder R

High throughput transmission optical projection tomography using low cost graphics processing unit Opt Express. 2009;17(25):22320-22332 - PMID: 20052155 - PMCID: PMC2805020 - DOI: 10.1364/OE.17.022320

Li C, Pastila RK, Pitsillides C, Runnels JM, Puoris'haag M, Cote D, Lin CP

Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence. Opt Express. 2010;18(2):988-99 - PMID: 20173920 - PMCID: PMC3369551 - DOI: 10.1364/OE.18.000988

Razansky RN, Rosenthal A, Mallas G, Razansky D, Jaffer FA, Ntziachristos V

Near-infrared fluorescence catheter system for two-dimensional intravascular imaging in vivo. Opt Express. 2010;18(11):11372-81 - PMID: 20588998 - DOI: 10.1364/OE.18.011372

Mansuripur M, Zakharian AR, Lesuffleur A, Oh SH, Jones RJ, Lindquist NC, Im H, Kobyakov A, Moloney JV

Plasmonic nano-structures for optical data storage. Opt Express. 2009;17(16):14001-14 - PMID: 19654809 - DOI: 10.1364/oe.17.014001

Lesuffleur A, Im H, Lindquist NC, Lim KS, Oh SH

Laser-illuminated nanohole arrays for multiplex plasmonic microarray sensing. Opt Express. 2008;16(1):219-24 - PMID: 18521151 - DOI: 10.1364/oe.16.000219

Curry A, Hwang WL, Wax A

Epi-illumination through the microscope objective applied to darkfield imaging and microspectroscopy of nanoparticle interaction with cells in culture. Opt Express. 2006;14(14):6535-42 - PMID: 19516830 - DOI: 10.1364/oe.14.006535

Henry F, Cote D, Randolph M, Rust E, Redmond R, Kochevar I, Lin CP, Winograd J

Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy. Plast Reconstr Surg. 2009;123:123S-30S - PMID: 19182671 - DOI: 10.1097/PRS.0b013e318191c5b8

Salthouse CD, Reynolds F, Tam JM, Josephson L, Mahmood U

Quantitative Measurement of Protease-Activity with Correction of Probe Delivery and Tissue Absorption Effects. Sens Actuat B-Chem. 2009;138(2):591-597 - PMID: 20161242 - PMCID: PMC2706141 - DOI: 10.1016/j.snb.2009.02.037

Marshansky V, Hosokawa H, Merkulova M, Bakulina A, Dip PV, Thaker YR, Bjargava A, Tonra JR, Ausiello DA, Grüber G

Structural model of a2-subunit N-terminus and its binding interface for Arf-GEF CTH2: Implication for regulation of V-ATPase, CTH2 function and rational drug design. Curr Top Membr. 2019;83:77-106 - PMID: 31196611 - DOI: 10.1016/bs.ctm.2019.01.008

Marquard AN, Carlson JCT, Weissleder R

Glass Chemistry to Analyze Human Cells under Adverse Conditions ACS Omega. 2019;4:11515−11521 - PMID: 31460257 - PMCID: PMC6682085 - DOI: 10.1021/acsomega.9b01036

Park JH, Park EK, Cho YK, Shin IS, Lee H

Normalizing the Optical Signal Enables Robust Assays with Lateral Flow Biosensors. ACS Omega. 2022;7(21):17723-17731 - PMID: 35664567 - PMCID: PMC9161384 - DOI: 10.1021/acsomega.2c00793

Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE

Design of a microfluidic chip for magnetic-activated sorting of one-bead-one-compound libraries. ACS Comb Sci. 2016;18(6):271-8 - PMID: 27124678 - PMCID: PMC5321554 - DOI: 10.1021/acscombsci.5b00180

Yekula A, Hsia T, Kitchen RR, Chakrabortty SK, Yu W, Batool MS, Lewis B, Szeglowski AJ, Weissleder R, Lee H, Chi AS, Batchelor T, Carter BS, Breakefield XO, Skog J, Balaj L

Longitudinal analysis of serum-derived extracellular vesicle RNA to monitor dacomitinib treatment response in EGFR amplified recurrent glioblastoma patients. Neurooncol Adv. 2023;:ePub - DOI: 10.1093/noajnl/vdad104

Yekula A, Hsia T, Kitchen RR, Chakrabortty SK, Yu W, Batool SM, Lewis B, Szeglowski AJ, Weissleder R, Lee H, Chi AS, Batchelor T, Carter BS, Breakefield XO, Skog J, Balaj L

Longitudinal analysis of serum-derived extracellular vesicle RNA to monitor dacomitinib treatment response in EGFR-amplified recurrent glioblastoma patients. Neurooncol Adv. 2023;5(1):vdad104 - PMID: 37811539 - PMCID: PMC10559837 - DOI: 10.1093/noajnl/vdad104

Kim JJ, Hong JS, Kim H, Choi M, Winter U, Lee H, Im H

CRISPR/Cas13a-assisted amplification-free miRNA biosensor via dark-field imaging and magnetic gold nanoparticles. Sens Diagn. 2024;3(8):1310-1318 - PMID: 39129860 - PMCID: PMC11308380 - DOI: 10.1039/d4sd00081a

Romero P, Pittet M, Dutoit V, Zippelius A, Lienard D, Lejeune F, Guillaume P, Rimoldi D, Valmori D, Speiser D, Cerottini J

Therapeutic cancer vaccines based on molecularly defined human tumor antigens. Vaccine. 2002;20(4):2-7 - PMID: 12477422 - DOI: 10.1016/s0264-410x(02)00380-8

Best SR, Peng S, Juang CM, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI

Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery. Vaccine. 2009;27(40):5450-9 - PMID: 19622402 - PMCID: PMC2745985 - DOI: 10.1016/j.vaccine.2009.07.005

Bouley R, Hawthorn G, Russo L, Lin H, Ausiello D, Brown D

Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment. Biol Cell. 2006;98(4):215-32 - PMID: 16563128 - DOI: 10.1042/BC20040054

Haller JL, Hyde D, Deliolanis N, de Kleine R, Niedre M, Ntziachristos V

Visualization of Pulmonary Inflammation Using Non-invasive Fluorescence Molecular Imaging. J Appl Physiol. 2008;104(3):795-802 - PMID: 18202169 - DOI: 10.1152/japplphysiol.00959.2007

Cazzanelli M, Vinegoni C, Pavesi L

Temperature dependence of the photo luminescence of all porous silicon microcavities. J. Appl. Phys. 1999;85;1760-4 J Appl Physiol. 1999;85:1760-4

Speiser D, Pittet M, Guillaume P, Lubenow N, Hoffman E, Cerottini J, Romero P

Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring. J Immunother. 2004;27:298-308 - PMID: 15235391 - DOI: 10.1097/00002371-200407000-00006

Hedgire SS, Mino-Kenudson M, Elmi A, Thayer S, Fernandez-Del Castillo C, Harisinghani MG

Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation. Int J Nanomedicine. 2014;9:1891-1896 - PMID: 24790431 - PMCID: PMC4000182 - DOI: 10.2147/IJN.S59788

Jeun M, Park S, Lee H, Lee KH

Highly sensitive detection of protein biomarkers via nuclear magnetic resonance biosensor with magnetically engineered nanoferrite particles Int J Nanomedicine. 2016;2016:11:5497–5503 - PMID: 27799772 - PMCID: PMC5085298 - DOI: 10.2147/IJN.S118156

Santos SA, Lukens AK, Coelho L, Nogueira F, Wirth DF, Mazitschek R, Moreira R, Paulo A

Exploring the 3-piperidin-4-yl-1H-indole scaffold as a novel antimalarial chemotype. Eur J Med Chem. 2015;102:320-333 - PMID: 26295174 - DOI: 10.1016/j.ejmech.2015.07.047

Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE

Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging. NMR Biomed. 2008;21(5):453-63 - PMID: 17918777 - PMCID: PMC2629945 - DOI: 10.1002/nbm.1209

Heidt T, Nahrendorf M

Multimodal iron oxide nanoparticles for hybrid biomedical imaging. NMR Biomed. 2012;26(7):756-65 - PMID: 23065771 - PMCID: PMC3549036 - DOI: 10.1002/nbm.2872

Framme C, Alt C, Schnell S, Sherwood M, Brinkmann R, Lin CP

Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam. Invest Ophth Vis Sci. 2007;48:1782-92 - PMID: 17389512 - DOI: 10.1167/iovs.06-0797

Wei X, Runnels J, Lin C

Selective uptake of indocyanine green by reticulocytes in circulation. Invest Ophth Vis Sci. 2003;44:4489-96 - PMID: 14507897 - PMCID: PMC2830078 - DOI: 10.1167/iovs.03-0041

Alt C, Runnels JM, Mortensen LJ, Zaher W, Lin C

In vivo imaging of microglia turnover in the mouse retina after ionizing radiation and dexamethasone treatment. Invest Ophthalmol Vis Sci. 2014;55(8):5314-5319 - PMID: 25082884 - DOI: 10.1167/iovs.14-14254

Yip S, Shah K

Stem-cell based therapies for brain tumors. Curr Opin Mol Ther. 2008;10:334-42 - PMID: 18683097

Wagner CA, Mohebbi N, Uhlig U, Giebisch GH, Breton S, Brown D, Geibel JP

Angiotensin II Stimulates H-ATPase Activity in Intercalated Cells from Isolated Mouse Connecting Tubules and Cortical Collecting Ducts. Cell Physiol Biochem. 2011;28(3):513-20 - PMID: 22116365 - PMCID: PMC3709473 - DOI: 10.1159/000335112

Montes M, Rufer N, Appay V, Reynard S, Pittet M, Speiser D, Guillaume P, Cerottini J, Romero P, Leyvraz S

Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy. Clin Exp Immunol. 2005;142:292-302 - PMID: 16232216 - PMCID: PMC1809512 - DOI: 10.1111/j.1365-2249.2005.02914.x

Ritz S, Cundall M, Gajewska B, Swirski F, Wiley R, Alvarez D, Coyle A, Stampfli M, Jordana M

The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo. Clin Exp Immunol. 2004;138(2):213-20 - PMID: 15498029 - PMCID: PMC1809215 - DOI: 10.1111/j.1365-2249.2004.02618.x

Moffat BA, Reddy GR, McConville P, Hall DE, Chenevert TL, Kopelman RR, Philbert M, Weissleder R, Rehemtulla A, Ross BD

A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI Mol Imaging. 2003;2:324-32 - PMID: 14717331 - DOI: 10.1162/15353500200303163

Lin Y, Weissleder R, Tung CH

Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging Mol Imaging. 2003;2:87-92 - PMID: 12964306 - DOI: 10.1162/15353500200303121

Josephson L, Mahmood U, Wunderbaldinger P, Tang Y, Weissleder R

Pan and sentinel lymph node visualization using a near-infrared fluorescent probe Mol Imaging. 2003;2:18-23 - PMID: 12926234 - DOI: 10.1162/15353500200302154

Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U

Miniaturized multichannel near infrared endoscope for mouse imaging Mol Imaging. 2003;2:350-7 - PMID: 14717334 - DOI: 10.1162/15353500200303166

Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R

Coded aperture nuclear scintigraphy: a novel small animal imaging technique Mol Imaging. 2002;1:344-53 - PMID: 12926230 - DOI: 10.1162/15353500200221362

Schellenberger EA, Bogdanov A Jr, Hogemann D, Tait J, Weissleder R, Josephson L

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Mol Imaging. 2002;1:102-7 - PMID: 12920851 - DOI: 10.1162/15353500200202103

Ntziachristos, V, Bremer C, Graves EE, Ripoll J, Weissleder R

In vivo tomographic imaging of near-infrared fluorescent probes Mol Imaging. 2002;1:82-8 - PMID: 12920848 - DOI: 10.1162/15353500200201121

Kircher MF, Josephson L, Weissleder R

Ratio imaging of enzyme activity using dual wavelength optical reporters Mol Imaging. 2003;1:89-95 - PMID: 12920849 - DOI: 10.1162/15353500200201124

Bogdanov A Jr, Matuszewski L, Bremer C, Petrovsky A, Weissleder R

Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets Mol Imaging. 2002;1:16-23 - PMID: 12920857 - DOI: 10.1162/15353500200200001

Chen WT, Tung CH, Weissleder R

Imaging reactive oxygen species in arthritis. Mol Imaging. 2004;3(3):159-62 - PMID: 15530251 - DOI: 10.1162/15353500200404124

Gillies R, Hoffman J, Lam K, Menkens A, Piwnica-Worms D, Sullivan D, Weissleder R.

Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents Mol Imaging. 2005;4:1-6

Wunder A, Schellenberger E, Mahmood U, Bogdanov A Jr, Muller-Ladner U, Weissleder R, Josephson L.

Methotrexate-induced accumulation of fluorescent annexin v in collagen-induced arthritis Mol Imaging. 2005;4(1):1-6 - PMID: 15967121 - DOI: 10.1162/15353500200504142

Montet-Abou K, Montet X, Weissleder R, Josephson L.

Transfection agent induced nanoparticle cell loading Mol Imaging. 2005;4(3):165-71 - PMID: 16194448 - DOI: 10.1162/15353500200505100

Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R

MIPortal: A High Capacity Server for Molecular Imaging Research. Mol Imaging. 2005;4(4):425-31 - PMID: 16285904 - DOI: 10.2310/7290.2005.05136

Chen WT, Khazaie K, Zhang G, Weissleder R, Tung CH

Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe Mol Imaging. 2005;4 (1):67-74 - PMID: 15912902

Kelly KA, Clemons PA, Yu AM, Weissleder R

High throughput identification of phage-derived imaging agents Mol Imaging. 2006;5(1):24-30 - PMID: 16779967

Sun EY, Josephson L, Weissleder R.

Clickable nanoparticles for targeted imaging Mol Imaging. 2006;(5) 2:122-128 - PMID: 16954026

Jaffer F, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R

Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials Mol Imaging. 2006;(5) 2 :85-92 - PMID: 16954022

Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V

Normalized transillumination of fluorescent proteins in small animals. Mol Imaging. 2006;5 (2):153-9 - PMID: 16954030

Montet-Abou K, Montet X, Weissleder R, Josephson L

Cell internalization of magnetic nanoparticles using transfection agents. Mol Imaging. 2007;(6) 1:1-9 - PMID: 17311760

Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J

Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging. 2007;6(2):96-107 - PMID: 17445504

Sheth RA, Upadhyay R, Weissleder R, Mahmood U

Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007;6(3):147-55 - PMID: 17532881

Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U

Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007;6(4):269-76 - PMID: 17711782

Hiller K, Waller C, Nahrendorf M, Bauer W, Jakob P

Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging. Mol Imaging. 2006;5(2):115-21 - PMID: 16954025

Runnels J, Zamiri P, Spencer J, Veilleux I, Wei X, Bogdanov AA, Lin CP

Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy. Mol Imaging. 2006;5:31-40 - PMID: 16779968 - PMCID: PMC2801601

Wei X, Sipkins D, Pitsillides C, Novak J, Georgakoudi I, Lin C

Real-time detection of circulating apoptotic cells by in vivo flow cytometry. Mol Imaging. 2005;4:415-6 - PMID: 16285902 - PMCID: PMC2801924 - DOI: 10.2310/7290.2005.05148

Mohammadi S, Pompa IR, Haberman V, Kako B, Lee RJ, Saylor P, Gao X, Esfahani SA, Heidari P, Ravi P, Sayan M, Efstathiou JA, Jacene HA, Kamran SC, Ng TSC

Combination metastasis-targeted external beam radiation therapy with 177Lu-PSMA-617 in patients with advanced castration-resistant prostate cancer. Pract Radiat Oncol. 2025;15(6):e597-e605 - PMID: 40274261 - DOI: 10.1016/j.prro.2025.03.010

Ayers BC, Aguirre AD, Sundt TM, Lu MT, Jassar A

An open-source, automated machine learning approach for large-scale image retrieval for thoracic aorta analysis studies. JAMIA Open. 2025;8(4):ooaf066 - PMID: 40662082 - PMCID: PMC12257624 - DOI: 10.1093/jamiaopen/ooaf066

Noiret L, Slater A, Higgins JM

Determinants of red blood cell alloantibody detection duration: analysis of multiply alloimmunized patients supports peritransfusion factors. Transfusion. 2017;57(8):1930-1937 - PMID: 28639314 - DOI: 10.1111/trf.14157

Turner GM, Zacharakis G, Soubret A, Ripoll J, Ntziachristos V.

Complete-angle projection diffuse optical tomography by use of early photons Opt Lett. 2005;30(4):409-11 - PMID: 15762444 - DOI: 10.1364/ol.30.000409

Deliolanis N, Lasser T, Hyde D, Soubret A, Ripoll J, Ntziachristos V

Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections. Opt Lett. 2007;32(4):382-4 - PMID: 17356660 - DOI: 10.1364/ol.32.000382

Razansky D, Vinegoni C, Ntziachristos V

Multispectral photoacoustic imaging of fluorochromes in small animals. Opt Lett. 2007;32(19):2891-3 - PMID: 17909608 - DOI: 10.1364/ol.32.002891

Alt C, Veilleux I, Lee H, Pitsillides CM, Cote D, Lin CP

Retinal flow cytometer. Opt Lett. 2007;32:3450-2 - PMID: 18059963 - PMCID: PMC2794483 - DOI: 10.1364/ol.32.003450

Biss DP, Sumorok D, Burns SA, Webb RH, Zhou Y, Bifano TG, Cote D, Veilleux I, Zamiri P, Lin CP

In vivo fluorescent imaging of the mouse retina using adaptive optics. Opt Lett. 2007;32:659-61 - PMID: 17308593 - PMCID: PMC2808135 - DOI: 10.1364/ol.32.000659

Razansky D, Vinegoni C, Ntziachristos V

Polarization-sensitive optoacoustic tomography of optically diffuse tissues. Opt Lett. 2008;33(20):2308-10 - PMID: 18923605 - DOI: 10.1364/ol.33.002308

Vinegoni C, Razansky D, Figueiredo JL, Nahrendorf M, Ntziachristos V, Weissleder R

Normalized Born ratio for fluorescence optical projection tomography. Opt Lett. 2009;34(3):319-21 - PMID: 19183644 - PMCID: PMC2771918 - DOI: 10.1364/ol.34.000319

Jones G, Marks D, Vinegoni C, Boppart S

High-spectral-resolution coherent anti-Stokes Raman scattering with interferometrically detected broadband chirped pulses. Opt Lett. 2006;31(10):1543-5 - PMID: 16642166 - DOI: 10.1364/ol.31.001543

Xu C, Vinegoni C, Ralston T, Luo W, Tan W, Boppart S

Spectroscopic spectral-domain optical coherence microscopy. Opt Lett. 2006;31:1079-81 - PMID: 16625909 - DOI: 10.1364/ol.31.001079

Kumar A, Chung E, Raymond S, van de Water J, Shah K, Fukumura D, Jain R, Bacskai B, Boas D

Feasibility of in vivo imaging of fluorescent proteins using lifetime contrast. Opt Lett. 2009;34(13):2066-8 - PMID: 19572001 - PMCID: PMC2872111 - DOI: 10.1364/ol.34.002066

Vinegoni C, Razansky D, Hilderbrand SA, Shao F, Ntziachristos V, Weissleder R

Transillumination fluorescence imaging in mice using biocompatible upconverting nanoparticles Opt Lett. 2009;34(17):2566-8 - PMID: 19724491 - PMCID: PMC2749971 - DOI: 10.1364/OL.34.002566

Novak J, Georgakoudi I, Wei X, Prossin A, Lin C

In vivo flow cytometer for real-time detection and quantification of circulating cells. Opt Lett. 2004;29:77-9 - PMID: 14719666 - PMCID: PMC2801600 - DOI: 10.1364/ol.29.000077

Lin C, Webb R

Fiber-coupled multiplexed confocal microscope. Opt Lett. 2000;25:954-6 - PMID: 18064238 - DOI: 10.1364/ol.25.000954

Swanson EA, Izatt JA, Hee MR, Huang D, Lin CP, Schuman JS, Puliafito CA, Fujimoto JG

In vivo retinal imaging by optical coherence tomography. Opt Lett. 1993;18(21):1864-6 - PMID: 19829430 - DOI: 10.1364/ol.18.001864

Vinegoni C, Fumene Feruglio P, Cortez-Retamozo V, Razansky D, Medoff BD, Ntziachristos V, Sbarbati A, Pittet M, Weissleder R

Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography. Opt Lett. 2010;35(7):1088-90 - PMID: 20364226 - PMCID: PMC2900933 - DOI: 10.1364/OL.35.001088

Ntziachristos V, Weissleder R

Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Opt Lett. 2001;26(12):893-5 - PMID: 18040483 - DOI: 10.1364/ol.26.000893

Ntziachristos V, Ripoll J, Weissleder R

Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Errata. Opt Lett. 2002;27(18):1652 - PMID: 18026531 - DOI: 10.1364/ol.27.001652

Ripoll J, Nieto-Vesperinas M, Weissleder R, Ntziachristos V

Fast analytical approximation for arbitrary geometries in diffuse optical tomography. Opt Lett. 2002;27(7):527-9 - PMID: 18007854 - DOI: 10.1364/ol.27.000527

Ntziachristos V, Ripoll J, Weissleder R

Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Opt Lett. 2002;27(5):333-5 - PMID: 18007794 - DOI: 10.1364/ol.27.000333

Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP

Mortality and extraintestinal cancers in patients with primary sclerosing cholangitis and inflammatory bowel disease. J Crohns Colitis. 2014;8(9):956-63 - PMID: 24559536 - PMCID: PMC4136996 - DOI: 10.1016/j.crohns.2014.01.019

Dubach JM, Vinegoni C, Weissleder R

Steady state anisotropy two-photon microscopy resolves multiple, spectrally similar fluorophores, enabling in vivo multilabel imaging. Opt Lett. 2014;39(15):4482-4485 - PMID: 25078208 - PMCID: PMC4341989 - DOI: 10.1364/OL.39.004482

Paudel HP, Alt C, Runnels J, Lin CP

Pupil plane differential detection microscopy. Opt Lett. 2018;43(18):4410-4412 - PMID: 30211877 - PMCID: PMC6492546 - DOI: 10.1364/OL.43.004410

Sun CC, Vaja V, Chen S, Theurl I, Stepanek A, Brown DE, Cappellini MD, Weiss G, Hong CC, Lin HY, Babitt JL

A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats. Nephrol Dial Transplant. 2013;28(7):1733-1743 - PMID: 23345622 - PMCID: PMC3707526 - DOI: 10.1093/ndt/gfs584

Zumbrennen-Bullough K, Babitt JL

The iron cycle in CKD: from genetics and experimental models to CKD patients. Nephrol Dial Transplant. 2013;29(2):263-73 - PMID: 24235084 - PMCID: PMC3910345 - DOI: 10.1093/ndt/gft443

Nahrendorf M, Hiller KH, Hu K, Zeijlemaker V, Griswold M, Bauer WR

Pacing in high field cardiac magnetic resonance imaging:. Pacing Clin Electrophysiol. 2004;27(5):671-4 - PMID: 15125728 - DOI: 10.1111/j.1540-8159.2004.00506.x

Veilleux I, Spencer JA, Biss DP, C

In vivo cell tracking with video rate multimodality laser scanning microscopy IEEE J Sel Top Quant. 2008;14:10:18

Lin CP, Kelly MW, Sibayan SA, Latina MA, Anderson RR

Selective Cell Killing by Microparticle Absorption of Pulsed Laser Radiation IEEE J Sel Top Quant. 1999;5:963-8

Vinegoni C, Lee S, Feruglio PF, Weissleder R

Advanced Motion Compensation Methods for Intravital Optical Microscopy. IEEE J Sel Top Quant. 2014;20(2):ePub - PMID: 24273405 - PMCID: PMC3832946 - DOI: 10.1109/JSTQE.2013.2279314

Vinegoni C, Dubach JM, Feruglio PF, Weissleder R

Two-Photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement IEEE J Sel Top Quant. 2016;22 (3):6801607 - PMID: 27440991 - PMCID: PMC4946648 - DOI: 10.1109/JSTQE.2015.2501384

Rigosi E, Frasnelli E, Vinegoni C, Antolini R, Anfora G, Vallortigara G, Haase A

Searching for anatomical correlates of olfactory lateralization in the honeybee antennal lobes: A morphological and behavioural study. Behav Brain Res.. 2011;221(1):290-4 - PMID: 21402106 - PMCID: PMC3089663 - DOI: 10.1016/j.bbr.2011.03.015

Chung J*, Issadore D*, Ullal A*, Lee K, Weissleder R*, Lee H*

Rare cell isolation and profiling on a hybrid magnetic/size-sorting chip Biomicrofluidics. 2013;7(5):54107 - PMID: 24404070 - PMCID: PMC3790798 - DOI: 10.1063/1.4821923

Zhao WN, Hylton NK, Wang J, Chindavong PS, Alural B, Kurtser I, Subramanian A, Mazitschek R, Perlis RH, Haggarty SJ

Activation of WNT and CREB signaling pathways in human neuronal cells in response to the Omega-3 fatty acid docosahexaenoic acid (DHA). Mol Cell Neurosci. 2019;99:103386 - PMID: 31202891 - PMCID: PMC7001743 - DOI: 10.1016/j.mcn.2019.06.006

Allport JR, Shinde Patil VR, Weissleder R

Murine Neuronal Progenitor Cells are Preferentially Recruited to Tumor Vasculature via alpha(4)-integrin and SDF-1alpha-Dependent Mechanisms. Cancer Biol Ther. 2004;3(9):838-44 - PMID: 15254391 - DOI: 10.4161/cbt.3.9.1036

Shah K.

Current Advances in Molecular Imaging of Gene and Cell Therapy for Cancer Cancer Biol Ther. 2005;4(5):518-523 - PMID: 15908803 - DOI: 10.4161/cbt.4.5.1706

Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel D, Grant S, Fisher P

Searching for a cure: Gene therapy for glioblastoma. Cancer Biol Ther. 2008;7(9):1335-40 - PMID: 18708757 - DOI: 10.4161/cbt.7.9.6408

Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus W, Ramakrishnan V, Sarkar D, Shah K, Curiel D, Grant S, Fisher P, Dent P

MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biol Ther. 2008;7:917-33 - PMID: 18376144 - DOI: 10.4161/cbt.7.6.5928

Wunderbaldinger P, Josephson L, Bremer C, Moore A, Weissleder R

Detection of lymph node metastases by contrast-enhanced MRI in an experimental model Magn Reson Med. 2002;47:292-7 - PMID: 11810672 - DOI: 10.1002/mrm.10068

Moore, A, Sun PZ, Cory D, Hogemann D, Weissleder R, Lipes MA

MRI of insulitis in autoimmune diabetes Magn Reson Med. 2002;47:751-8 - PMID: 11948737 - DOI: 10.1002/mrm.10110

Kim YR, Savellano MD, Savellano DH, Weissleder R, Bogdanov A Jr

Measurement of tumor interstitial volume fraction: Method and implication for drug delivery Magn Reson Med. 2004;52(3):485-94 - PMID: 15334566 - DOI: 10.1002/mrm.20182

Chen JW, Pham W, Weissleder R, Bogdanov A Jr

Human myeloperoxidase: A potential target for molecular MR imaging in atherosclerosis. Magn Reson Med. 2004;52(5):1021-8 - PMID: 15508166 - DOI: 10.1002/mrm.20270

Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L.

Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle Magn Reson Med. 2005;54(3):718-724 - PMID: 16086367 - DOI: 10.1002/mrm.20617

Hong R, Cima MJ, Weissleder R, Josephson L

Magnetic microparticle aggregation for viscosity determination by MR. Magn Reson Med. 2008;59:515-520 - PMID: 18306403 - PMCID: PMC2740908 - DOI: 10.1002/mrm.21526

Schmitt M, Potthast A, Sosnovik DE, Polimeni JR, Wiggins GC, Triantafyllou C, Wald LL

A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla. Magn Reson Med. 2008;59:1431-1439 - PMID: 18506789 - PMCID: PMC2548273 - DOI: 10.1002/mrm.21598

Streif J, Nahrendorf M, Hiller K, Waller C, Wiesmann F, Rommel E, Haase A, Bauer W

In vivo assessment of absolute perfusion and intracapillary blood volume in the murine myocardium by spin labeling magnetic resonance imaging. Magn Reson Med. 2005;53(3):584-92 - PMID: 15723416 - DOI: 10.1002/mrm.20327

Vonken EJ, Korosoglou G, Yu J, Schar M, Weissleder R, Stuber M

On the dual contrast enhancement mechanism in frequency-selective inversion-recovery magnetic resonance angiography (IRON-MRA). Magn Reson Med. 2009;62(2):314-24 - PMID: 19526511 - PMCID: PMC2742771 - DOI: 10.1002/mrm.22027

Zaharchuk G, Bogdanov AA, Marota JJ, Shimizu-Sasamata M, Weisskoff RM, Kwong KK, Jenkins BG, Weissleder R, Rosen BR

Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): a steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction. Magn Reson Med. 1998;40(5):666-78 - PMID: 9797148 - DOI: 10.1002/mrm.1910400504

Mandeville JB, Marota JJ, Kosofsky BE, Keltner JR, Weissleder R, Rosen BR, Weisskoff RM

Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med. 1998;39(4):615-24 - PMID: 9543424 - DOI: 10.1002/mrm.1910390415

Mandeville JB, Moore J, Chesler DA, Garrido L, Weissleder R, Weisskoff RM

Dynamic liver imaging with iron oxide agents: effects of size and biodistribution on contrast. Magn Reson Med. 1997;37(6):885-90 - PMID: 9178240 - DOI: 10.1002/mrm.1910370613

Harika L, Weissleder R, Poss K, Zimmer C, Papisov MI, Brady TJ

MR lymphography with a lymphotropic T1-type MR contrast agent: Gd-DTPA-PGM. Magn Reson Med. 1995;33(1):88-92 - PMID: 7891541 - DOI: 10.1002/mrm.1910330113

Shen T, Weissleder R, Papisov M, Bogdanov A, Brady TJ

Monocrystalline iron oxide nanocompounds (MION): physicochemical properties. Magn Reson Med. 1993;29(5):599-604 - PMID: 8505895 - DOI: 10.1002/mrm.1910290504

Weissleder R

Target-specific superparamagnetic MR contrast agents. Magn Reson Med. 1991;22(2):209-12; discussion 213-5 - PMID: 1812348 - DOI: 10.1002/mrm.1910220209

Streif JU, Herold V, Szimtenings M, Lanz TE, Nahrendorf M, Wiesmann F, Rommel E, Haase A

In vivo time-resolved quantitative motion mapping of the murine myocardium with phase contrast MRI. Magn Reson Med. 2003;49(2):315-21 - PMID: 12541252 - DOI: 10.1002/mrm.10342

Chousterman BG, Swirski FK

Innate Response Activator B cells: origins and functions. Int Immunol. 2015;27(10):537-41 - PMID: 25957266 - PMCID: PMC4693688 - DOI: 10.1093/intimm/dxv028

Brown D, Paunescu TG, Breton S, Marshansky V

Regulation of the V-ATPase in kidney epithelial cells: dual role in acid-base homeostasis and vesicle trafficking. J Exp Biol. 2009;212(Pt 11):1762-72 - PMID: 19448085 - PMCID: PMC2683016 - DOI: 10.1242/jeb.028803

Shum WW, Da Silva N, Brown D, Breton S

Regulation of luminal acidification in the male reproductive tract via cell-cell crosstalk. J Exp Biol. 2009;212(Pt 11):1753-61 - PMID: 19448084 - PMCID: PMC2683015 - DOI: 10.1242/jeb.027284

Brown D, Breton S

Mitochondria-rich, proton-secreting epithelial cells. J Exp Biol. 1996;199(Pt 11):2345-58 - PMID: 9114500 - DOI: 10.1242/jeb.199.11.2345

Brown D, Smith PJ, Breton S

Role of V-ATPase-rich cells in acidification of the male reproductive tract. J Exp Biol. 1997;200(Pt 2):257-62 - PMID: 9050233 - DOI: 10.1242/jeb.200.2.257

Brown D, Breton S

H(+)V-ATPase-dependent luminal acidification in the kidney collecting duct and the epididymis/vas deferens: vesicle recycling and transcytotic pathways. J Exp Biol. 2000;203(Pt 1):137-45 - PMID: 10600682 - DOI: 10.1242/jeb.203.1.137

Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R

Novel Factor XIII Probes for Blood Coagulation Imaging Chembiochem. 2003;4:897-899 - PMID: 12964167 - DOI: 10.1002/cbic.200300602

Tung CH, Gerszten RE, Jaffer FA, Weissleder R

A novel near-infrared fluorescence sensor for detection of thrombin activation in blood Chembiochem. 2002;3:207-11 - PMID: 11921399 - DOI: 10.1002/1439-7633(20020301)3:2/3<207::AID-CBIC207>3.0.CO;2-B

Tung CH, Lin Y, Moon WK, Weissleder R

A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging Chembiochem. 2002;3:784-6 - PMID: 12203978 - DOI: 10.1002/1439-7633(20020802)3:8<784::AID-CBIC784>3.0.CO;2-X

Perez JM, Josephson L, Weissleder R

Use of magnetic nanoparticles as nanosensors to probe for molecular interactions Chembiochem. 2004;5:261-4 - PMID: 14997516 - DOI: 10.1002/cbic.200300730

Schellenberger EA, Reynolds F, Weissleder R, Josephson L

Surface-functionalized nanoparticle library yields probes for apoptotic cells Chembiochem. 2004;5:275-9 - PMID: 14997519 - DOI: 10.1002/cbic.200300713

Schellenberger EA, Weissleder R, Josephson L

Optimal modification of annexin v with fluorescent dyes Chembiochem. 2004;5:271-4 - PMID: 14997518 - DOI: 10.1002/cbic.200300741

Pham W, Kircher MF, Weissleder R, Tung CH

Enhancing membrane permeability by Fatty acylation of oligoarginine peptides. Chembiochem. 2004;5(8):1148-51 - PMID: 15300843 - DOI: 10.1002/cbic.200400063

Koch AM, Reynolds F, Merkle HP, Weissleder R, Josephson L.

Transport Of Surface-Modified Nanoparticles Through Cell Monolayers Chembiochem. 2005;6(2):337-345 - PMID: 15651046 - DOI: 10.1002/cbic.200400174

Law B, Weissleder R, Tung CH.

Mechanism-Based Fluorescent Reporter for Protein Kinase A Detection Chembiochem. 2005;6(8):1361-1367 - PMID: 16010698 - DOI: 10.1002/cbic.200500027

Ho NH, Weissleder R, Tung CH

A Self-Immolative Reporter For beta-Galactosidase Sensing. Chembiochem. 2007;8:560-566 - PMID: 17300128 - DOI: 10.1002/cbic.200600386

Reiner T, Earley S, Turetsky A, Weissleder R

Bioorthogonal Small-Molecule Ligands for PARP1 Imaging in Living Cells. Chembiochem. 2010;11(17):2374-2377 - PMID: 20967817 - PMCID: PMC3034378 - DOI: 10.1002/cbic.201000477

Addicks E, Mazitschek R, Giannis A

Synthesis and biological investigation of novel tricyclic benzodiazepinedione-based RGD analogues. Chembiochem. 2002;3(11):1078-88 - PMID: 12404633 - DOI: 10.1002/1439-7633(20021104)3:11<1078::AID-CBIC1078>3.0.CO;2-2

Derbyshire ER, Zuzarte-Luís V, Magalhães AD, Kato N, Sanschagrin PC, Wang J, Zhou W, Miduturu CV, Mazitschek R, Sliz P, Mota MM, Gray NS, Clardy J

Chemical Interrogation of the Malaria Kinome. Chembiochem. 2014;15(13):1920-30 - PMID: 25111632 - PMCID: PMC4237307 - DOI: 10.1002/cbic.201400025

Keppel P, Sohr B, Kuba W, Goldeck M, Skrinjar P, Carlson JCT, Mikula H

Tetrazine-Triggered Bioorthogonal Cleavage of trans-Cyclooctene-Caged Phenols Using a Minimal Self-Immolative Linker Strategy. Chembiochem. 2022;23(20):e202200363 - PMID: 35921044 - PMCID: PMC9804162 - DOI: 10.1002/cbic.202200363

Haase A, Rigosi E, Trona F, Anfora G, Vallortigara G, Antolini R, Vinegoni C

In-vivo two-photon imaging of the honey bee antennal lobe. Biomed Opt Express. 2010;2(1):131-8 - PMID: 21326643 - PMCID: PMC3028488 - DOI: 10.1364/BOE.1.000131

Deliolanis NC, Wurdinger T, Pike L, Tannous BA, Breakefield XO, Weissleder R, Ntziachristos V

In vivo tomographic imaging of red-shifted fluorescent proteins. Biomed Opt Express. 2011;2(4):887-900 - PMID: 21483611 - PMCID: PMC3072128 - DOI: 10.1364/BOE.2.000887

Bélanger E, Henry FP, Vallée R, Randolph MA, Kochevar IE, Winograd JM, Lin CP, Côté D

In vivo evaluation of demyelination and remyelination in a nerve crush injury model. Biomed Opt Express. 2011;2(9):2698-2708 - PMID: 22091449 - PMCID: PMC3184878 - DOI: 10.1364/BOE.2.002698

Wang K, Liu TM, Wu J, Horton NG, Lin CP, Xu C

Three-color femtosecond source for simultaneous excitation of three fluorescent proteins in two-photon fluorescence microscopy. Biomed Opt Express. 2012;3(9):1972-7 - PMID: 23024893 - PMCID: PMC3447541 - DOI: 10.1364/BOE.3.001972

Vinegoni C, Lee S, Feruglio PF, Marzola P, Nahrendorf M, Weissleder R

Sequential average segmented microscopy for high signal-to-noise ratio motion-artifact-free in vivo heart imaging. Biomed Opt Express. 2013;4(10):2095-106 - PMID: 24156067 - PMCID: PMC3799669 - DOI: 10.1364/BOE.4.002095

Turcotte R, Alt C, Mortensen LJ, Lin CP

Characterization of multiphoton microscopy in the bone marrow following intravital laser osteotomy. Biomed Opt Express. 2014;5(10):3578-88 - PMID: 25360374 - PMCID: PMC4206326 - DOI: 10.1364/BOE.5.003578

Mortensen LJ, Alt C, Turcotte R, Masek M, Liu TM, Côté DC, Xu C, Intini G, Lin CP

Femtosecond laser bone ablation with a high repetition rate fiber laser source. Biomed Opt Express. 2014;6(1):32-42 - PMID: 25657872 - PMCID: PMC4317121 - DOI: 10.1364/BOE.6.000032

Charan K, Li B, Wang M, Lin CP, Xu C

Fiber-based tunable repetition rate source for deep tissue two-photon fluorescence microscopy. Biomed Opt Express. 2018;9(5):2304-2311 - PMID: 29760989 - PMCID: PMC5946790 - DOI: 10.1364/BOE.9.002304

Ling R, Tahir W, Lin HY, Lee H, Tian L

High-throughput intensity diffraction tomography with a computational microscope. Biomed Opt Express. 2018;9(5):2130-2141 - PMID: 29760975 - PMCID: PMC5946776 - DOI: 10.1364/BOE.9.002130

Bernstein L, Ramier A, Wu J, Aiello VD, Beland MJ, Lin CP, Yun SH

Ultrahigh resolution spectral-domain optical coherence tomography using the 1000-1600 nm spectral band. Biomed Opt Express. 2022;13(4):1939-1947 - PMID: 35519264 - PMCID: PMC9045918 - DOI: 10.1364/BOE.443654

Remsen LG, McCormick CI, Roman-Goldstein S, Nilaver G, Weissleder R, Bogdanov A, Hellström I, Kroll RA, Neuwelt EA

MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis. AJNR Am J Neuroradiol. 1996;17(3):411-8 - PMID: 8881233 - PMCID: PMC8337991

Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N

Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006;105:445-54 - PMID: 16961141 - DOI: 10.3171/jns.2006.105.3.445

Kim D, Niemierko A, Hwang WL, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Oh KS, Loeffler JS, Shih HA

Histopathological prognostic factors of recurrence following definitive therapy for atypical and malignant meningiomas. J Neurosurg. 2017;128(4):1123-1132 - PMID: 28621619 - DOI: 10.3171/2016.11.JNS16913

J.W. Chen, R.L. Belford, R.B. Clarkson

Second-Sphere and Outer-Sphere Proton Relaxation of Paramagnetic Contrast Agents J Phys Chem B. 1998;102:2117-2130

J.W. Chen, R.B. Clarkson, R.L. Belford

Rotational Dynamics of MRI Paramagnetic Contrast Agents in Viscous Media J Phys Chem B. 1996;100:8093-8100

J.W. Chen, F.P. Auteri, D.E. Budil, R.L. Belford, R.B. Clarkson

Use of EPR to Investigate Rotational Dynamics of MRI Paramagnetic Contrast Agents J Phys Chem B. 1994;98:13452

Pulli B, Chen JW

Imaging Neuroinflammation - from Bench to Bedside. J Clin Cell Immunol. 2014;5:ePub - PMID: 25525560 - PMCID: PMC4266918 - DOI: 10.4172/2155-9899.1000226

Huang XJ, Im HS, Yarimaga O, Kim JH, Lee DH, Kim HS, Choi YK

Direct electrochemistry of uric acid at chemically assembled carboxylated single-walled carbon nanotubes netlike electrode. J Phys Chem B. 2006;110(43):21850-6 - PMID: 17064150 - DOI: 10.1021/jp063749q

Carney BJ, Shah K

Migration and fate of therapeutic stem cells in different brain disease models. Neuroscience. 2011;197:37-47 - PMID: 21946010 - PMCID: PMC3589128 - DOI: 10.1016/j.neuroscience.2011.08.063

Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS

Genetically engineered T cells to target EGFRvIII expressing glioblastoma. J Neuro-Oncol. 2009;94(3):373-82 - PMID: 19387557 - PMCID: PMC2730985 - DOI: 10.1007/s11060-009-9889-1

Waters JD, Sanchez C, Sahin A, Futalan D, Gonda DD, Scheer JK, Akers J, Palanichamy K, Waterman P, Chakravarti A, Weissleder R, Morse B, Marsh N, Furfine E, Chen CC, Carvajal I, Carter BS

CT322, a VEGFR-2 antagonist, demonstrates anti-glioma efficacy in orthotopic brain tumor model as a single agent or in combination with temozolomide and radiation therapy. J Neurooncol. 2012;110(1):37-48 - PMID: 22875706 - PMCID: PMC4291475 - DOI: 10.1007/s11060-012-0948-7

Lebow ES, Hwang WL, Zieminski S, Wang Y, Niemierko A, Mehan WA, Oh KS, Khandekar M, Willers H, Shih HA

Early experience with hippocampal avoidance whole brain radiation therapy and simultaneous integrated boost for brain metastases. J Neurooncol. 2020;148(1):81-88 - PMID: 32307637 - DOI: 10.1007/s11060-020-03491-y

Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM

RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport. Mol Biol Cell. 2000;11(9):3155-68 - PMID: 10982407 - PMCID: PMC14982 - DOI: 10.1091/mbc.11.9.3155

Cabrero JR, Serrador JM, Barreiro O, Mittelbrunn M, Naranjo-Suárez S, Martín-Cófreces N, Vicente-Manzanares M, Mazitschek R, Bradner JE, Avila J, Valenzuela-Fernández A, Sánchez-Madrid F

Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell. 2006;17(8):3435-45 - PMID: 16738306 - PMCID: PMC1525231 - DOI: 10.1091/mbc.E06-01-0008

Guan Y, Meurer M, Raghavan S, Rebane A, Lindquist JR, Santos S, Kats I, Davidson MW, Mazitschek R, Hughes TE, Drobizhev M, Knop M, Shah JV

Live Cell Multi-Photon Fluorescence Correlation Spectroscopy with an Improved Large Stokes Shift Fluorescent Protein. Mol Biol Cell. 2015;26(11):2054-66 - PMID: 25877871 - PMCID: PMC4472016 - DOI: 10.1091/mbc.E14-10-1473

Oudin MJ, Miller MA, Klazen JA, Kosciuk T, Lussiez A, Hughes SK, Tadros J, Bear JE, Lauffenburger DA, Gertler FB

MenaINV mediates synergistic crosstalk between signaling pathways driving chemotaxis and haptotaxis. Mol Biol Cell. 2016;27(20):3085-3094 - PMID: 27559126 - PMCID: PMC5063616 - DOI: 10.1091/mbc.E16-04-0212

Simerzin A, Ackerman EE, Fujimaki K, Kohler RH, Iwamoto Y, Heltberg MS, Jambhekar A, Weissleder R, Lahav G

Cell Confluency Affects p53 Dynamics in Response to DNA Damage. Mol Biol Cell. 2025;36(6):br16 - PMID: 40202833 - PMCID: PMC12206509 - DOI: 10.1091/mbc.E24-09-0394

Celso CL, Wu JW, Lin CP

In vivo imaging of hematopoietic stem cells and their microenvironment. J Biophotonics. 2009;2(11):619-631 - PMID: 19847800 - DOI: 10.1002/jbio.200910072

Feruglio PF, Vinegoni C, Fexon L, Thurber G, Sbarbati A, Weissleder R

Noise suppressed, multifocus image fusion for enhanced intraoperative navigation. J Biophotonics. 2012;6(4):363-70 - PMID: 22887724 - PMCID: PMC3779878 - DOI: 10.1002/jbio.201200086

Turcotte R, Wu JW, Lin CP

Intravital multiphoton photoconversion with a cell membrane dye. J Biophotonics. 2016;10(2):206-210 - PMID: 27433967 - DOI: 10.1002/jbio.201600077

Li YX, Gautam V, Brüstle A, Cockburn IA, Daria VR, Gillespie C, Gaus K, Alt C, Lee WM

Flexible polygon-mirror based laser scanning microscope platform for multiphoton in-vivo imaging. J Biophotonics. 2017;10(11):1526-1537 - PMID: 28164461 - DOI: 10.1002/jbio.201600289

Tung CH, Mueller S, Weissleder R

Novel branching membrane translocational peptide as gene delivery vector Bioorg Med Chem. 2002;10:3609-14 - PMID: 12213476 - DOI: 10.1016/s0968-0896(02)00248-1

Ho NH, Weissleder R, Tung CH

Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate. Bioorg Med Chem. 2006;16:2599-2602 - PMID: 16517162 - DOI: 10.1016/j.bmcl.2006.02.045

Estiu G, West N, Mazitschek R, Greenberg E, Bradner JE, Wiest O

On the inhibition of histone deacetylase 8. Bioorg Med Chem. 2010;18(11):4103-4110 - PMID: 20472442 - PMCID: PMC3245874 - DOI: 10.1016/j.bmc.2010.03.080

Randino R, Gazzerro P, Mazitschek R, Rodriquez M

Synthesis and biological evaluation of Santacruzamate-A based analogues. Bioorg Med Chem. 2017;25(24):6486-6491 - PMID: 29100734 - DOI: 10.1016/j.bmc.2017.10.026

El-Awady R, Saleh E, Hamoudi R, Ramadan WS, Mazitschek R, Nael MA, Elokely KM, Abou-Gharbia M, Childers WE, Srinivasulu V, Aloum L, Menon V, Al-Tel TH

Discovery of novel class of histone deacetylase inhibitors as potential anticancer agents. Bioorg Med Chem. 2021;42:116251 - PMID: 34116381 - DOI: 10.1016/j.bmc.2021.116251

Sun N, Liu Y, Lee H, Weissleder R, Ham D

CMOS RF Biosensor Utilizing Nuclear Magnetic Resonance IEEE J Solid-ST Circ. 2009;44:1629-1643

Sun N, Yoon TJ, Lee H, Andress W, Weissleder R, Ham D

Palm NMR and 1-Chip NMR IEEE J Solid-ST Circ. 2011;46(1):342-352

Goergen CJ, Sosnovik DE

From Molecules to Myofibers: Multiscale Imaging of the Myocardium. J Cardiovasc Transl Res. 2011;4(4):493-503 - PMID: 21643889 - PMCID: PMC3370890 - DOI: 10.1007/s12265-011-9284-0

Preston MA, Harisinghani MG, Mucci L, Witiuk K, Breau RH

Diagnostic tests in urology: magnetic resonance imaging (MRI) for the staging of prostate cancer. BJU Int. 2013;111(3):514-7 - PMID: 23320634 - DOI: 10.1111/j.1464-410X.2012.11447.x

Jayasena V, Brown D, Shtatland T, Gold L

In vitro selection of RNA specifically cleaved by bacteriophage T4 RegB endonuclease. Biochemistry-US. 1996;35:2349-56 - PMID: 8652576 - DOI: 10.1021/bi951879b

Senior S, Mans L, VanGuilder H, Kelly K, Hendrich M, Elgren T

Catecholase activity associated with copper-S100B. Biochemistry-US. 2003;42:4392-7 - PMID: 12693934 - DOI: 10.1021/bi0205799

Elgren T, Orville A, Kelly K, Lipscomb J, Ohlendorf D, Que L

Crystal structure and resonance Raman studies of protocatechuate 3,4-dioxygenase complexed with 3,4-dihydroxyphenylacetate. Biochemistry-US. 1997;36:11504-13 - PMID: 9298971 - DOI: 10.1021/bi970691k

Pérez-Medina C, Hak S, Reiner T, Fayad ZA, Nahrendorf M, Mulder WJM

Integrating nanomedicine and imaging. Philos Trans A Math Phys Eng Sci. 2017;375(2107):ePub - PMID: 29038380 - PMCID: PMC5647268 - DOI: 10.1098/rsta.2017.0110

Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP

Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model. Pancreas. 2008;37(4):440-4 - PMID: 18953259 - PMCID: PMC3806135 - DOI: 10.1097/MPA.0b013e31817c5113

Kwon S, Kim S, Giovannucci EL, Hidalgo M, Markey MK, Bovik AC, Kwon MJ, Kim KJ, Im H, Park JY, Bang S, Park SW, Song SY, Chung MJ

Lewis Antigen Phenotype and Survival of Patients With Pancreatic Cancer. Pancreas. 2020;49(10):1348-1354 - PMID: 33122524 - DOI: 10.1097/MPA.0000000000001687

Ahrens CC, Chiswick EL, Ravindra KC, Miller MA, Ramseier J, Isaacson KB, Lauffenburger DA, Griffith LG

Development and Application of the Metalloprotease Activity Multi-plexed Bead-based Immunoassay (MAMBI). Biochemistry. 2019;58(38):3938-3942 - PMID: 31474112 - DOI: 10.1021/acs.biochem.9b00584

Spear MA, Breakefield XO, Beltzer J, Schuback D, Weissleder R, Pardo FS, Ladner R

Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells Cancer Gene Ther. 2001;8:506-11 - PMID: 11498772 - DOI: 10.1038/sj.cgt.7700334

Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U

In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008;1:84-94 - PMID: 18633456 - PMCID: PMC2510813 - DOI: 10.1593/tlo.08118

McDermott S, Thayer SP, Fernandez-Del Castillo C, Mino-Kenudson M, Weissleder R, Harisinghani MG

Accurate prediction of nodal status in preoperative patients with pancreatic ductal adenocarcinoma using next-gen nanoparticle. Transl Oncol. 2013;6(6):670-5 - PMID: 24466369 - PMCID: PMC3890701 - DOI: 10.1593/tlo.13400

Dorsey ER, Yvonne Chan YF, McConnell MV, Shaw SY, Trister AD, Friend SH

The Use of Smartphones for Health Research. Acad Med. 2017;92(2):157-160 - PMID: 27119325 - DOI: 10.1097/ACM.0000000000001205

Moore A, Marecos E, Simonova M, Weissleder R, Bogdanov A

Novel gliosarcoma cell line expressing green fluorescent protein: A model for quantitative assessment of angiogenesis. Microvasc Res. 1998;56(3):145-53 - PMID: 9828152 - DOI: 10.1006/mvre.1998.2102

Waller C, Hiller KH, Albrecht M, Hu K, Nahrendorf M, Gattenl

Microvascular adaptation to coronary stenosis in the rat heart in vivo: a serial magnetic resonance imaging study. Microvasc Res. 2003;66(3):173-82 - PMID: 14609522 - DOI: 10.1016/s0026-2862(03)00058-x

Hilgendorf I, Swirski FK

Making a Difference: Monocyte Heterogeneity in Cardiovascular Disease. Curr Atheroscler Rep. 2012;14(5):450-9 - PMID: 22847772 - PMCID: PMC3436972 - DOI: 10.1007/s11883-012-0274-8

Aguirre AD, Shelton KT

Remote monitoring in the use of extracorporeal membrane oxygenation and acute mechanical circulatory support. Curr Opin Crit Care. 2022;28(3):308-314 - PMID: 35653252 - DOI: 10.1097/MCC.0000000000000949

Yoneyama T, Gorry M, Miller MA, Gaither-Davis A, Lin Y, Moss ML, Griffith LG, Lauffenburger DA, Stabile LP, Herman JG, Vujanovic NL

Modification of proteolytic activity matrix analysis (PrAMA) to measure ADAM10 and ADAM17 sheddase activities in cell and tissue lysates. J Cancer. 2017;8(19):3916-3932 - PMID: 29187866 - PMCID: PMC5705993 - DOI: 10.7150/jca.20779

Yoneyama T, Gorry M, Sobo-Vujanovic A, Lin Y, Vujanovic L, Gaither-Davis A, Moss ML, Miller MA, Griffith LG, Lauffenburger DA, Stabile LP, Herman J, Vujanovic NL

ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker. J Cancer. 2018;9(14):2559-2570 - PMID: 30026855 - PMCID: PMC6036891 - DOI: 10.7150/jca.24601

Graves EE, Ripoll J, Weissleder R, Ntziachristos V

A submillimeter resolution fluorescence molecular imaging system for small animal imaging Med Phys. 2003;30:901-11 - PMID: 12772999 - DOI: 10.1118/1.1568977

Ntziachristos V, Weissleder R

Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media Med Phys. 2002;29:803-9 - PMID: 12033576 - DOI: 10.1118/1.1470209

Turner GM, Soubret A, Ntziachristos V

Inversion with early photons. Med Phys. 2007;34(4):1405-11 - PMID: 17500472 - DOI: 10.1118/1.2437103

Razansky D, Ntziachristos V

Hybrid photoacoustic fluorescence molecular tomography using finite-element-based inversion. Med Phys. 2007;34(11):4293-301 - PMID: 18072494 - DOI: 10.1118/1.2786866

Allport JR, Weissleder R

In vivo imaging of gene and cell therapies Exp Hematol. 2001;29:1237-46 - PMID: 11698119 - DOI: 10.1016/s0301-472x(01)00739-1

Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M

Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells. Exp Hematol. 2010;38(4):333-9 - PMID: 20167247 - PMCID: PMC3965294 - DOI: 10.1016/j.exphem.2010.02.003

Luthria G, Lauffenburger D, Miller MA

Cell-Cell Communication Networks in Tissue: Toward Quantitatively Linking Structure with Function. Curr Opin Syst Biol. 2021;27:ePub - PMID: 34693081 - PMCID: PMC8530179 - DOI: 10.1016/j.coisb.2021.05.002

Owokuhaisa J, Turyakira E, Ssedyabane F, Tusubira D, Kajabwangu R, Musinguzi P, Galiwango M, Randall TC, Kakongi N, Castro CM, Atukunda EC, Maling S

Barriers and facilitators of retention in care after cervical cancer screening: patients' and healthcare providers' perspectives. BMC Womens Health. 2024;24(1):516 - PMID: 39272088 - PMCID: PMC11401415 - DOI: 10.1186/s12905-024-03343-1

O'Neill MJ, Weissleder R, Gervais DA, Hahn PF, Mueller PR

Tunneled peritoneal catheter placement under sonographic and fluoroscopic guidance in the palliative treatment of malignant ascites AJR Am J Roentgenol. 2001;177:615-8 - PMID: 11517056 - DOI: 10.2214/ajr.177.3.1770615

Harisinghani MG, Saini S, Weissleder R, Hahn PF, Yantiss RK, Tempany C, Wood BJ, Mueller PR

MR lymphangiography using ultrasmall superparamagnetic iron oxide in patients with primary abdominal and pelvic malignancies: radiographic-pathologic correlation AJR Am J Roentgenol. 1999;172:1347-51 - PMID: 10227514 - DOI: 10.2214/ajr.172.5.10227514

Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, Weissleder R

Ferumoxtran-10-Enhanced MR Lymphangiography: Does Contrast-Enhanced Imaging Alone Suffice for Accurate Lymph Node Characterization? AJR Am J Roentgenol. 2006;186(1):144-8 - PMID: 16357394 - DOI: 10.2214/AJR.04.1287

Saksena M, Harisinghani M, Hahn P, Kim J, Saokar A, King B, Weissleder R

Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers. AJR Am J Roentgenol. 2006;187(6):W582-8 - PMID: 17114509 - DOI: 10.2214/AJR.05.0873

Goldberg M, Pivovarov M, Mayo-Smith W, Bhalla M, Blickman J, Bramson R, Boland G, Llewellyn H, Halpern E

Application of wavelet compression to digitized radiographs. AJR Am J Roentgenol. 1994;163:463-8 - PMID: 8037051 - DOI: 10.2214/ajr.163.2.8037051

Pandharipande PV, Harisinghani MG, Ozanne EM, Specht MC, Hur C, Lee JM, Gazelle GS

Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis. AJR Am J Roentgenol. 2008;191:1308-19 - PMID: 18941062 - DOI: 10.2214/AJR.07.3861

Pandharipande PV, Mora JT, Uppot RN, Goehler A, Braschi M, Halpern EF, Gazelle GS, Harisinghani MG

Lymphotropic nanoparticle-enhanced MRI for independent prediction of lymph node malignancy: a logistic regression model. AJR Am J Roentgenol. 2009;193(3):W230-7 - PMID: 19696264 - DOI: 10.2214/AJR.08.2175

Baier ND, Hahn PF, Gervais DA, Samir A, Halpern EF, Mueller PR, Harisinghani MG

Fine-needle aspiration biopsy of thyroid nodules: experience in a cohort of 944 patients. AJR Am J Roentgenol. 2009;193(4):1175-9 - PMID: 19770344 - DOI: 10.2214/AJR.08.1840

Gee MS, Kim JY, Gervais DA, Hahn PF, Mueller PR

Management of abdominal and pelvic abscesses that persist despite satisfactory percutaneous drainage catheter placement. AJR Am J Roentgenol. 2010;194(3):815-20 - PMID: 20173165 - DOI: 10.2214/AJR.09.3282

Uppot RN, Harisinghani MG, Gervais DA

Imaging-guided percutaneous renal biopsy: rationale and approach. AJR Am J Roentgenol. 2010;194(6):1443-9 - PMID: 20489082 - DOI: 10.2214/AJR.10.4427

Sena BF, Stern JP, Pandharipande PV, Klemm B, Bulman J, Pedrosa I, Rofsky NM

Screening patients to assess renal function before administering gadolinium chelates: assessment of the choyke questionnaire. AJR Am J Roentgenol. 2010;195(2):424-8 - PMID: 20651199 - PMCID: PMC6247784 - DOI: 10.2214/AJR.09.3803

Cronin CG, Harisinghani MG, Catalano O, Blake MA

Multitechnique imaging findings of prolene plug hernia repair. AJR Am J Roentgenol. 2010;195(3):701-6 - PMID: 20729449 - DOI: 10.2214/AJR.09.4142

Callahan RJ, Bogdanov A, Fischman AJ, Brady TJ, Weissleder R

Preclinical evaluation and phase I clinical trial of a 99mTc-labeled synthetic polymer used in blood pool imaging. AJR Am J Roentgenol. 1998;171(1):137-43 - PMID: 9648777 - DOI: 10.2214/ajr.171.1.9648777

Weissleder R

Can gadolinium be safely given in renal failure? AJR Am J Roentgenol. 1996;167(1):278-9 - PMID: 8659405 - DOI: 10.2214/ajr.167.1.8659405

Lu DS, Saini S, Hahn PF, Goldberg M, Lee MJ, Weissleder R, Gerard B, Halpern E, Cats A

T2-weighted MR imaging of the upper part of the abdomen: should fat suppression be used routinely? AJR Am J Roentgenol. 1994;162(5):1095-100 - PMID: 8165989 - DOI: 10.2214/ajr.162.5.8165989

Frank H, Weissleder R, Bogdanov AA, Brady TJ

Detection of pulmonary emboli by using MR angiography with MPEG-PL-GdDTPA: an experimental study in rabbits. AJR Am J Roentgenol. 1994;162(5):1041-6 - PMID: 8165978 - DOI: 10.2214/ajr.162.5.8165978

Frank H, Weissleder R, Brady TJ

Enhancement of MR angiography with iron oxide: preliminary studies in whole-blood phantom and in animals. AJR Am J Roentgenol. 1994;162(1):209-13 - PMID: 8273667 - DOI: 10.2214/ajr.162.1.8273667

Chew FS, Weissleder R

Radiation-induced osteochondroma. AJR Am J Roentgenol. 1991;157(4):792 - PMID: 1892038 - DOI: 10.2214/ajr.157.4.1892038

Chew FS, Weissleder R

Mediastinal thymolipoma. AJR Am J Roentgenol. 1991;157(3):468 - PMID: 1872228 - DOI: 10.2214/ajr.157.3.1872228

Weissleder R, Reimer P, Lee AS, Wittenberg J, Brady TJ

MR receptor imaging: ultrasmall iron oxide particles targeted to asialoglycoprotein receptors. AJR Am J Roentgenol. 1990;155(6):1161-7 - PMID: 2122660 - DOI: 10.2214/ajr.155.6.2122660

Fretz CJ, Stark DD, Metz CE, Elizondo G, Weissleder R, Shen JH, Wittenberg J, Simeone J, Ferrucci JT

Detection of hepatic metastases: comparison of contrast-enhanced CT, unenhanced MR imaging, and iron oxide-enhanced MR imaging. AJR Am J Roentgenol. 1990;155(4):763-70 - PMID: 2119106 - DOI: 10.2214/ajr.155.4.2119106

Hahn PF, Stark DD, Saini S, Rummeny E, Elizondo G, Weissleder R, Wittenberg J, Ferrucci JT

The differential diagnosis of ringed hepatic lesions in MR imaging. AJR Am J Roentgenol. 1990;154(2):287-90 - PMID: 2153330 - DOI: 10.2214/ajr.154.2.2153330

Rummeny E, Saini S, Stark DD, Weissleder R, Compton CC, Ferrucci JT

Detection of hepatic metastases with MR imaging: spin-echo vs phase-contrast pulse sequences at 0.6 T. AJR Am J Roentgenol. 1989;153(6):1207-11 - PMID: 2683677 - DOI: 10.2214/ajr.153.6.1207

Rummeny E, Saini S, Wittenberg J, Compton C, Hahn PF, Mueller PR, Simeone JF, Stark DD, Weissleder R, Dousset MG

MR imaging of liver neoplasms. AJR Am J Roentgenol. 1989;152(3):493-9 - PMID: 2536996 - DOI: 10.2214/ajr.152.3.493

Weissleder R, Elizondo G, Stark DD, Hahn PF, Marfil J, Gonzalez JF, Saini S, Todd LE, Ferrucci JT

The diagnosis of splenic lymphoma by MR imaging: value of superparamagnetic iron oxide. AJR Am J Roentgenol. 1989;152(1):175-80 - PMID: 2783273 - DOI: 10.2214/ajr.152.1.175

Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, White DL, Jacobs P, Lewis J

Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol. 1989;152(1):167-73 - PMID: 2783272 - DOI: 10.2214/ajr.152.1.167

Rummeny E, Weissleder R, Stark DD, Saini S, Compton CC, Bennett W, Hahn PF, Wittenberg J, Malt RA, Ferrucci JT

Primary liver tumors: diagnosis by MR imaging. AJR Am J Roentgenol. 1989;152(1):63-72 - PMID: 2535770 - DOI: 10.2214/ajr.152.1.63

Wittenberg J, Stark DD, Forman BH, Hahn PF, Saini S, Weissleder R, Rummeny E, Ferrucci JT

Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR Am J Roentgenol. 1988;151(1):79-84 - PMID: 3259825 - DOI: 10.2214/ajr.151.1.79

Hahn PF, Weissleder R, Stark DD, Saini S, Elizondo G, Ferrucci JT

MR imaging of focal splenic tumors. AJR Am J Roentgenol. 1988;150(4):823-7 - PMID: 3279735 - DOI: 10.2214/ajr.150.4.823

Weissleder R, Saini S, Stark DD, Wittenberg J, Ferrucci JT

Dual-contrast MR imaging of liver cancer in rats. AJR Am J Roentgenol. 1988;150(3):561-6 - PMID: 3257610 - DOI: 10.2214/ajr.150.3.561

Weissleder R, Hahn PF, Stark DD, Rummeny E, Saini S, Wittenberg J, Ferrucci JT

MR imaging of splenic metastases: ferrite-enhanced detection in rats. AJR Am J Roentgenol. 1987;149(4):723-6 - PMID: 3498320 - DOI: 10.2214/ajr.149.4.723

Cronin CG, Gervais DA, Hahn PF, Arellano R, Guimaraes AR, Mueller PR

Treatment of Deep Intramuscular and Musculoskeletal Abscess: Experience With 99 CT-Guided Percutaneous Catheter Drainage Procedures. AJR Am J Roentgenol. 2011;196(5):1182-1188 - PMID: 21512090 - DOI: 10.2214/AJR.09.4082

Gee MS, Nimkin K, Hsu M, Israel EJ, Biller JA, Katz AJ, Mino-Kenudson M, Harisinghani MG

Prospective Evaluation of MR Enterography as the Primary Imaging Modality for Pediatric Crohn Disease Assessment. AJR Am J Roentgenol. 2011;197(1):224-31 - PMID: 21701034 - PMCID: PMC3711021 - DOI: 10.2214/AJR.10.5970

Duigenan S, Gee MS

Imaging of pediatric patients with inflammatory bowel disease. AJR Am J Roentgenol. 2012;199(4):907-15 - PMID: 22997386 - DOI: 10.2214/AJR.11.7966

Elmi A, Tabatabaei S, Talab SS, Hedgire SS, Cao K, Harisinghani M

Incidental findings at initial imaging workup of patients with prostate cancer: clinical significance and outcomes. AJR Am J Roentgenol. 2012;199(6):1305-11 - PMID: 23169722 - DOI: 10.2214/AJR.11.8417

Rajesh A, Cloud G, Harisinghani MG

Improving the quality of manuscript reviews: impact of introducing a structured electronic template to submit reviews. AJR Am J Roentgenol. 2013;200(1):20-3 - PMID: 23255737 - DOI: 10.2214/AJR.11.8299

Gunn AJ, Seethamraju RT, Hedgire S, Elmi A, Daniels GH, Harisinghani MG

Imaging Behavior of the Normal Adrenal on Ferumoxytol-Enhanced MRI: Preliminary Findings. AJR Am J Roentgenol. 2013;201(1):117-21 - PMID: 23789664 - DOI: 10.2214/AJR.12.9357

Hedgire SS, McDermott S, Borczuk D, Elmi A, Saini S, Harisinghani MG

The Spectrum of IgG4-Related Disease in the Abdomen and Pelvis. AJR Am J Roentgenol. 2013;201(1):14-22 - PMID: 23789654 - DOI: 10.2214/AJR.12.9995

Dhyani M, Anupindi SA, Ayyala R, Hahn PF, Gee MS

Defining an imaging algorithm for noncystic splenic lesions identified in young patients. AJR Am J Roentgenol. 2013;201(6):W893-9 - PMID: 24261396 - DOI: 10.2214/AJR.12.10105

Marcus C, Whitworth PW, Surasi DS, Pai SI, Subramaniam RM

PET/CT in the management of thyroid cancers. AJR Am J Roentgenol. 2014;202(6):1316-29 - PMID: 24848831 - DOI: 10.2214/AJR.13.11673

Magudia K, Arleo EK, Porter KK, Ng TSC

A Practical Guide for Paid Family and Medical Leave in Radiology, From the AJR Special Series on DEI. AJR Am J Roentgenol. 2023;221(5):575-581 - PMID: 37195791 - DOI: 10.2214/AJR.23.29327

Robbins CS, Swirski FK

Newly discovered innate response activator B cells: crucial responders against microbial sepsis. Expert Rev Clin Immunol. 2012;8(5):405-7 - PMID: 22882214 - DOI: 10.1586/eci.12.32

Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V.

Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography J Biomed Opt. 2005;10(4):44019 - PMID: 16178652 - DOI: 10.1117/1.1993427

Ntziachristos V, Turner G, Dunham J, Windsor S, Soubret A, Ripoll J, Shih HA

Planar fluorescence imaging using normalized data. J Biomed Opt. 2005;10(6):64007 - PMID: 16409072 - DOI: 10.1117/1.2136148

Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA

Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy. J Biomed Opt. 2006;11(2):21009 - PMID: 16674184 - DOI: 10.1117/1.2186337

Hsiao JK, Law B, Weissleder R, Tung CH

In-vivo imaging of tumor associated urokinase-type plasminogen activator activity. J Biomed Opt. 2006;11(3):34013 - PMID: 16822063 - DOI: 10.1117/1.2204029

Niedre MJ, Turner GM, Ntziachristos V

Time-resolved imaging of optical coefficients through murine chest cavities. J Biomed Opt. 2006;11(6):064017 - PMID: 17212540 - DOI: 10.1117/1.2400702

Kim P, Puoris'haag M, Cote D, Lin CP, Yun SH

In vivo confocal and multiphoton microendoscopy. J Biomed Opt. 2008;13(1):010501 - PMID: 18315346 - PMCID: PMC2752311 - DOI: 10.1117/1.2839043

Deliolanis NC, Kasmieh R, Wurdinger T, Tannous BA, Shah K, Ntziachristos V

Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications. J Biomed Opt. 2008;13(4):044008 - PMID: 19021336 - PMCID: PMC2749214 - DOI: 10.1117/1.2967184

Deliolanis N, Dunham J, Wurdinger T, Figueiredo J, Bakhos T, Ntziachristos V

In-vivo imaging of murine tumors using complete-angle projection fluorescence molecular tomography. J Biomed Opt. 2009;14(3):030509 - PMID: 19566290 - PMCID: PMC2881930 - DOI: 10.1117/1.3149854

Lee H, Alt C, Pitsillides C, Lin CP

Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration. J Biomed Opt. 2007;12:064034 - PMID: 18163850 - DOI: 10.1117/1.2804078

Boutrus S, Greiner C, Hwu D, Chan M, Kuperwasser C, Lin CP, Georgakoudi I

Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells. J Biomed Opt. 2007;12:020507 - PMID: 17477705 - PMCID: PMC2798734 - DOI: 10.1117/1.2722733

Roegener J, Brinkmann R, Lin CP

Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells. J Biomed Opt. 2004;9:367-71 - PMID: 15065904 - DOI: 10.1117/1.1646413

Alt C, Framme C, Schnell S, Lee H, Brinkmann R, Lin CP

Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner. J Biomed Opt. 2006;10(6):064014 - PMID: 16409079 - DOI: 10.1117/1.2136314

Calfon MA, Vinegoni C, Ntziachristos V, Jaffer FA

Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques. J Biomed Opt. 2010;15(1):011107 - PMID: 20210433 - PMCID: PMC3188610 - DOI: 10.1117/1.3280282

Runnels JM*, Carlson AL*, Pitsillides C, Thompson B, Wu J, Spencer JA, Kohler JMJ, Azab AK, Moreau AS, Rodig SJ, Kung AL, Anderson KC, Ghobrial IM, Lin CP

Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy J Biomed Opt. 2011;16(1):011006 - PMID: 21280893 - PMCID: PMC3033873 - DOI: 10.1117/1.3520571

Hajjarian Z, Xi J, Jaffer FA, Tearney GJ, Nadkarni SK

Intravascular laser speckle imaging catheter for the mechanical evaluation of the arterial wall. J Biomed Opt. 2011;16(2):026005 - PMID: 21361689 - PMCID: PMC3056316 - DOI: 10.1117/1.3533322

Imitola J, Cote D, Rasmussen S, Xie XS, Liu Y, Chitnis T, Sidman RL, Lin CP, Khoury SJ

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice. J Biomed Opt. 2011;16(2):021109 - PMID: 21361672 - PMCID: PMC3061329 - DOI: 10.1117/1.3533312

Zettergren E, Vickers D, Runnels J, Murthy SK, Lin CP, Niedre M

Instrument for fluorescence sensing of circulating cells with diffuse light in mice in vivo. J Biomed Opt. 2012;17(3):037001 - PMID: 22502573 - PMCID: PMC3380949 - DOI: 10.1117/1.JBO.17.3.037001

Kim Y, Higgins JM, Dasari RR, Suresh S, Park Y

Anisotropic light scattering of individual sickle red blood cells. J Biomed Opt. 2012;17(4):040501 - PMID: 22559667 - PMCID: PMC3602817 - DOI: 10.1117/1.JBO.17.4.040501

Lee S, Vinegoni C, Feruglio PF, Weissleder R

Improved intravital microscopy via synchronization of respiration and holder stabilization. J Biomed Opt. 2012;17(9):96018-1 - PMID: 23085919 - PMCID: PMC3449295 - DOI: 10.1117/1.JBO.17.9.096018

Achilefu S, Contag CH, Savitsky AP, Weissleder R

Chemical and Genetic Sensors in Biomedical Research. J Biomed Opt. 2005;10(4):41201 - PMID: 23171967

Pestana N, Mortensen LJ, Runnels JP, Vickers D, Murthy SK, Lin CP, Niedre M

Improved diffuse fluorescence flow cytometer prototype for high sensitivity detection of rare circulating cells in vivo. J Biomed Opt. 2013;18(7):77002 - PMID: 23831714 - PMCID: PMC3702234 - DOI: 10.1117/1.JBO.18.7.077002

Lee S, Courties G, Nahrendorf M, Weissleder R, Vinegoni C

Motion characterization scheme to minimize motion artifacts in intravital microscopy. J Biomed Opt. 2017;22(3):36005 - PMID: 28253383 - PMCID: PMC5333764 - DOI: 10.1117/1.JBO.22.3.036005

Pera V, Tan X, Runnels J, Sardesai N, Lin CP, Niedre M

Diffuse fluorescence fiber probe for in vivo detection of circulating cells. J Biomed Opt. 2017;22(3):37004 - PMID: 28290598 - PMCID: PMC5348644 - DOI: 10.1117/1.JBO.22.3.037004

Patil R, Tan X, Bartosik P, Detappe A, Runnels JM, Ghobrial I, Lin CP, Niedre M

Fluorescence monitoring of rare circulating tumor cell and cluster dissemination in a multiple myeloma xenograft model in vivo. J Biomed Opt. 2019;24(8):1-11 - PMID: 31456386 - PMCID: PMC6983486 - DOI: 10.1117/1.JBO.24.8.085004

Fumene Feruglio P, Vinegoni C, Weissleder R

Extended dynamic range imaging for noise mitigation in fluorescence anisotropy imaging. J Biomed Opt. 2020;25(8):ePub - PMID: 32820624 - PMCID: PMC7439791 - DOI: 10.1117/1.JBO.25.8.086003

Tung CH

Fluorescent peptide probes for in vivo diagnostic imaging. Biopolymers. 2004;76(5):391-403 - PMID: 15389488 - DOI: 10.1002/bip.20139

Liu X, Nielsen GP, Rosenberg AE, Waterman PR, Yang W, Choy E, Sassi S, Yang S, Harmon DC, Yang C, Schwab JH, Kobayashi E, Mankin HJ, Xavier R, Weissleder R, Duan Z, Hornicek FJ

Establishment and characterization of a novel chordoma cell line: CH22. J Orthop Res. 2012;30(10):1666-73 - PMID: 22504929 - DOI: 10.1002/jor.22113

Querol Sans M*, Chen JW*, Weissleder R, Bogdanov AA

Myeloperoxidase Activity Imaging Using (67)Ga Labeled Substrate. Mol Imaging Biol. 2005;7(6):403-10 - PMID: 16292477 - DOI: 10.1007/s11307-005-0020-5

Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R

In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging. Mol Imaging Biol. 2006;8(4):201-7 - PMID: 16791746 - DOI: 10.1007/s11307-006-0043-6

Guimaraes AR, Ross R, Figuereido JL, Waterman P, Weissleder R

MRI with Magnetic Nanoparticles Monitors Downstream Anti-Angiogenic Effects of mTOR Inhibition. Mol Imaging Biol. 2011;13(2):314-20 - PMID: 20559742 - DOI: 10.1007/s11307-010-0357-2

Thurber GM, Weissleder R

Quantitating Antibody Uptake In Vivo: Conditional Dependence on Antigen Expression Levels. Mol Imaging Biol. 2011;13(4):623-32 - PMID: 20809210 - PMCID: PMC3000888 - DOI: 10.1007/s11307-010-0397-7

Saxena A, Kessinger CW, Thompson B, McCarthy JR, Iwamoto Y, Lin CP, Jaffer FA

High-Resolution Optical Mapping of Inflammatory Macrophages Following Endovascular Arterial Injury. Mol Imaging Biol. 2013;15(3):282-9 - PMID: 23090852 - PMCID: PMC3650124 - DOI: 10.1007/s11307-012-0599-2

Lartey FM, Ahn GO, Shen B, Cord KT, Smith T, Chua JY, Rosenblum S, Liu H, James ML, Chernikova S, Lee SW, Pisani LJ, Tirouvanziam R, Chen JW, Palmer TD, Chin FT, Guzman R, Graves EE, Loo BW

PET Imaging of Stroke-Induced Neuroinflammation in Mice Using [(18)F]PBR06. Mol Imaging Biol. 2013;16(1):109-17 - PMID: 23836504 - PMCID: PMC4141125 - DOI: 10.1007/s11307-013-0664-5

Lartey FM, Ahn GO, Ali R, Rosenblum S, Miao Z, Arksey N, Shen B, Colomer MV, Rafat M, Liu H, Alejandre-Alcazar MA, Chen JW, Palmer T, Chin FT, Guzman R, Loo BW, Graves E

The Relationship Between Serial [(18) F]PBR06 PET Imaging of Microglial Activation and Motor Function Following Stroke in Mice. Mol Imaging Biol. 2014;16(6):821-9 - PMID: 24865401 - PMCID: PMC4237703 - DOI: 10.1007/s11307-014-0745-0

Carlucci G, Carney B, Brand C, Kossatz S, Irwin CP, Carlin SD, Keliher EJ, Weber W, Reiner T

Dual-Modality Optical/PET Imaging of PARP1 in Glioblastoma. Mol Imaging Biol. 2015;17(6):848-55 - PMID: 25895168 - PMCID: PMC4609241 - DOI: 10.1007/s11307-015-0858-0

Davis RW, Eggleston H, Johnson F, Nahrendorf M, Bock PE, Peterson T, Panizzi P

In Vivo Tracking of Streptococcal Infections of Subcutaneous Origin in a Murine Model. Mol Imaging Biol. 2015;17(6):793-801 - PMID: 25921659 - PMCID: PMC4807872 - DOI: 10.1007/s11307-015-0856-2

Mazitschek R, Baumhof P, Giannis A

Peptidomimetics and angiogenesis. Mini Rev Med Chem. 2002;2(5):491-506 - PMID: 12370049 - DOI: 10.2174/1389557023405710

Spear MA, Herrlinger U, Rainov N, Pechan P, Weissleder R, Breakefield XO

Targeting gene therapy vectors to CNS malignancies. J Neurovirol. 1998;4(2):133-47 - PMID: 9584951 - DOI: 10.3109/13550289809114514

Chang K, Jaffer F

Advances in fluorescence imaging of the cardiovascular system. J Nucl Cardiol. 2008;15(3):417-28 - PMID: 18513648 - DOI: 10.1016/j.nuclcard.2008.03.001

Panizzi P, Stone JR, Nahrendorf M

Endocarditis and molecular imaging. J Nucl Cardiol. 2014;21(3):486-95 - PMID: 24797384 - PMCID: PMC4106242 - DOI: 10.1007/s12350-014-9902-8

Nahrendorf M, Abbate A, Narula J

Deciphering post-infarct inflammation: Should it heal, would it hurt? J Nucl Cardiol. 2020;27(6):2100-2102 - PMID: 32086743 - DOI: 10.1007/s12350-020-02053-z

Nahrendorf M, Abbate A, Narula J

Correction to: Deciphering post-infarct inflammation: Should it heal, would it hurt? J Nucl Cardiol. 2020;27(4):1384 - PMID: 32140993 - DOI: 10.1007/s12350-020-02090-8

Lin JR, Wang H, Collins AB, Stone JR

Tongue necrosis and systemic vascular amyloidosis. Hum Pathol. 2011;42(5):734-737 - PMID: 21236468 - DOI: 10.1016/j.humpath.2010.08.011

Bouley R, Hasler U, Lu HA, Nunes P, Brown D

Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus. Semin Nephrol. 2008;28:266-78 - PMID: 18519087 - PMCID: PMC2494582 - DOI: 10.1016/j.semnephrol.2008.03.010

Brown D

Aquaporins and vasopressin signaling in kidney health and disease: introduction. Semin Nephrol. 2008;28:215-6 - PMID: 18519082 - DOI: 10.1016/j.semnephrol.2008.03.001

Lin HY

Transforming Growth Factor-β and the Kidney Revisited: Introduction. Semin Nephrol. 2012;32(3):225-7 - PMID: 22835452 - DOI: 10.1016/j.semnephrol.2012.04.010

Yeung CH, Breton S, Setiawan I, Xu Y, Lang F, Cooper TG

Increased luminal pH in the epididymis of infertile c-ros knockout mice and the expression of sodium-hydrogen exchangers and vacuolar proton pump H+-ATPase. Mol Reprod Dev. 2004;68(2):159-68 - PMID: 15095336 - DOI: 10.1002/mrd.20067

Kim B, Breton S

Localization of the gap junction protein, connexin 43, and E-cadherin/Cadherin-1 in the proximal mouse epididymis. Mol Reprod Dev. 2015;82(10):723 - PMID: 26331361

Ho NH, Weissleder R, Tung CH

Development of water-soluble far-red fluorogenic dyes for enzyme sensing Tetrahedron. 2006;62:578-585

McCarthy JR, Capetta SH, Melfi PJ, Bruckner C

Use of Ag(II) as a removable ion in porphyrin chemistry: Diol cleavage products of [meso-tetraphenyl-2,3-diolchlorinato]Ag(II) Tetrahedron. 2003;59:9137-46

Haimovich JS, Kolossváry M, Alam R, Padrós-Valls R, Lu MT, Aguirre AD

Risk stratification of chest pain in the emergency department using artificial intelligence applied to electrocardiograms. Open Heart. 2025;12(2):ePub - PMID: 40889954 - PMCID: PMC12406858 - DOI: 10.1136/openhrt-2025-003343

Boiselle PM, Patz EF, Vining DJ, Weissleder R, Shepard JA, McLoud TC

Imaging of mediastinal lymph nodes: CT, MR, and FDG PET. Radiographics. 1998;18(5):1061-9 - PMID: 9747607 - DOI: 10.1148/radiographics.18.5.9747607

Sahani DV, Bonaffini PA, Catalano OA, Guimaraes AR, Blake MA

State-of-the-Art PET/CT of the Pancreas: Current Role and Emerging Indications. Radiographics. 2012;32(4):1133-58 - PMID: 22786999 - PMCID: PMC6939848 - DOI: 10.1148/rg.324115143

Wilbur DC, Madi K, Colvin RB, Duncan LM, Faquin WC, Ferry JA, Frosch MP, Houser SL, Kradin RL, Lauwers GY, Louis DN, Mark EJ, Mino-Kenudson M, Misdraji J, Nielsen GP, Pitman MB, Rosenberg AE, Smith RN, Sohani AR, Stone JR, Tambouret RH, Wu CL, Young RH, Zembowicz A, Klietmann W

Whole-slide imaging digital pathology as a platform for teleconsultation: a pilot study using paired subspecialist correlations. Arch Pathol Lab Med. 2009;133(12):1949-53 - PMID: 19961250 - PMCID: PMC3694269 - DOI: 10.1043/1543-2165-133.12.1949

Louis DN, Gerber GK, Baron JM, Bry L, Dighe AS, Getz G, Higgins JM, Kuo FC, Lane WJ, Michaelson JS, Le LP, Mermel CH, Gilbertson JR, Golden JA

Computational pathology: an emerging definition. Arch Pathol Lab Med. 2014;138(9):1133-8 - PMID: 25171694 - DOI: 10.5858/arpa.2014-0034-ED

Bogdanov A, Wright SC, Marecos EM, Bogdanova A, Martin C, Petherick P, Weissleder R

A long-circulating co-polymer in "passive targeting" to solid tumors. J Drug Target. 1997;4(5):321-30 - PMID: 9169989 - DOI: 10.3109/10611869708995848

Salthouse CD, Weissleder R, Mahmood U

Development of a Time Domain Fluorimeter for Fluorescent Lifetime Multiplexing Analysis. IEEE T Biomed Circuits Syst. 2008;2(3):204-211 - PMID: 19830273 - PMCID: PMC2760943 - DOI: 10.1109/TBCAS.2008.2003195

Merkulova M, McKee M, Dip PV, Gruber G, Marshansky V

N-terminal domain of the V-ATPase a2-subunit displays integral membrane protein properties. Protein Sci. 2010;19(10):1850-1862 - PMID: 20669186 - PMCID: PMC2998721 - DOI: 10.1002/pro.470

Smith TB, Cortez-Retamozo V, Grigoryeva LS, Hill E, Pittet MJ, Da Silva N

Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis. Andrology. 2014;2(5):755-62 - PMID: 25082073 - PMCID: PMC4396827 - DOI: 10.1111/j.2047-2927.2014.00251.x

Sullivan R, Légaré C, Lamontagne-Proulx J, Breton S, Soulet D

Revisiting structure/functions of the human epididymis. Andrology. 2019;7(5):748-757 - PMID: 31033221 - DOI: 10.1111/andr.12633

Breton S, Nair AV, Battistone MA

Epithelial dynamics in the epididymis: role in the maturation, protection, and storage of spermatozoa. Andrology. 2019;7(5):631-643 - PMID: 31044554 - PMCID: PMC6688936 - DOI: 10.1111/andr.12632

Soubret A, Ntziachristos V

Fluorescence molecular tomography in the presence of background fluorescence. Phys Med Biol. 2006;51:3983-4001 - PMID: 16885619 - DOI: 10.1088/0031-9155/51/16/007

Razansky D, Vinegoni C, Ntziachristos V

Imaging of mesoscopic-scale organisms using selective-plane optoacoustic tomography. Phys Med Biol. 2009;54:2769-2777 - PMID: 19369709 - DOI: 10.1088/0031-9155/54/9/012

Fumene Feruglio P, Vinegoni C, Gros J, Sbarbati A, Weissleder R

Block matching 3D random noise filtering for absorption optical projection tomography. Phys Med Biol. 2010;55(18):5401-5415 - PMID: 20736500 - PMCID: PMC2934766 - DOI: 10.1088/0031-9155/55/18/009

Zettergren E, Swamy T, Runnels J, Lin CP, Niedre M

Tomographic sensing and localization of fluorescently labeled circulating cells in mice in vivo. Phys Med Biol. 2012;57(14):4627-41 - PMID: 22750660 - PMCID: PMC3555500 - DOI: 10.1088/0031-9155/57/14/4627

Hartmann C, Patil R, Lin CP, Niedre MJ

Fluorescence detection, enumeration and characterization of single circulating cells in vivo technology, applications and future prospects. Phys Med Biol. 2017;:ePub - PMID: 29115281 - DOI: 10.1088/1361-6560/aa98f9

Hartmann C, Patil R, Lin CP, Niedre M

Fluorescence detection, enumeration and characterization of single circulating cells in vivo: technology, applications and future prospects. Phys Med Biol. 2017;63(1):01TR01 - PMID: 29240559 - PMCID: PMC5753400 - DOI: 10.1088/1361-6560/aa98f9

Yonker LM, Badaki-Makun O, Alvarez-Carcamo B, Cross C, Okuducu Y, Appleman L, Greatorex J, Onu RE, Santos C, Petherbridge R, Foy BH, Cereaga D, Naiman M, Castro I, Haller L, Guthrie LB, Higgins JM, Lewandrowski KB, Irimia D

Monocyte Anisocytosis is Associated with Sepsis in Children with Suspected Infection. Shock. 2024;63(3):385-389 - PMID: 39749928 - PMCID: PMC12450074 - DOI: 10.1097/SHK.0000000000002502

Razansky D, Deliolanis N, Vinegoni C, Ntziachristos V

Deep Tissue Optical and Optoacoustic Molecular Imaging Technologies for Small Animal Research and Drug Discovery. Curr Pharm Biotechnol. 2012;13(4):504-22 - PMID: 22216767 - DOI: 10.2174/138920112799436258

Papisov M, Weissleder R

Drug delivery to lymphatic tissue. Crit Rev Ther Drug Carrier Syst. 1996;13(1-2):57-84 - PMID: 8853959

Wiesmann F, Herold V, Streiff JU, Nahrendorf M, Neubauer S, Rommel E, Haase A

Novel insights into LV remodeling after murine myocardial infarction by in vivo magnetic resonance tissue velocity mapping. Int J Cardiovasc Imaging. 2004;20(4):289-91 - PMID: 15529911 - DOI: 10.1023/b:caim.0000041945.64887.f4

Joseph P, Ishai A, MacNabb M, Abdelbaky A, Lavender ZR, Ruskin J, Nahrendorf M, Tawakol A

Atrial fibrillation is associated with hematopoietic tissue activation and arterial inflammation. Int J Cardiovasc Imaging. 2015;32(1):113-119 - PMID: 26411879 - PMCID: PMC4730873 - DOI: 10.1007/s10554-015-0766-z

Thurber GM, Figueiredo JL, Weissleder R

Detection limits of intraoperative near infrared imaging for tumor resection. J Surg Oncol. 2010;102(7):758-64 - PMID: 20872807 - PMCID: PMC3758114 - DOI: 10.1002/jso.21735

Gomez NR, Kouniavsky G, Tsai HL, Somervell H, Pai SI, Tufano RP, Umbricht C, Kowalski J, Dackiw AP, Zeiger MA

Tumor size and presence of calcifications on ultrasonography are pre-operative predictors of lymph node metastases in patients with papillary thyroid cancer. J Surg Oncol. 2011;104(6):613-6 - PMID: 21744345 - DOI: 10.1002/jso.21891

Gutiérrez OM, Sun CC, Chen W, Babitt JL, Lin HY

Statement of Concern about a Commercial Assay Used to Measure Soluble Hemojuvelin in Humans. Am J Nephrol. 2012;36(4):332-333 - PMID: 23006450 - DOI: 10.1159/000342519

Breton S, Tyszkowski R, Sabolic I, Brown D

Postnatal development of H+ ATPase (proton-pump)-rich cells in rat epididymis. Histochem Cell Biol. 1999;111(2):97-105 - PMID: 10090570 - DOI: 10.1007/s004180050339

Ananthakrishnan AN, Cheng A, Cagan A, Cai T, Gainer VS, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP

Mode of Childbirth and Long-Term Outcomes in Women with Inflammatory Bowel Diseases. Dig Dis Sci. 2014;60(2):471-7 - PMID: 25213079 - PMCID: PMC4304947 - DOI: 10.1007/s10620-014-3353-6

Corey KE, Kartoun U, Zheng H, Shaw SY

Development and Validation of an Algorithm to Identify Nonalcoholic Fatty Liver Disease in the Electronic Medical Record. Dig Dis Sci. 2015;61(3):913-9 - PMID: 26537487 - PMCID: PMC4761309 - DOI: 10.1007/s10620-015-3952-x

Castro MM, Kim B, Hill E, Fialho MC, Puga LC, Freitas MB, Breton S, Machado-Neves M

The expression patterns of aquaporin 9, vacuolar H(+)-ATPase, and cytokeratin 5 in the epididymis of the common vampire bat. Histochem Cell Biol. 2016;147(1):39-48 - PMID: 27549752 - DOI: 10.1007/s00418-016-1477-9

McDermott S, Hedgire SS, Hahn PF, Mueller PR, Harisinghani MG

Image-Guided Biopsy of Suspicious Lymph Nodes in Patients with Known Primary Malignancies. J Vasc Interv Radiol. 2012;23(3):371-6 - PMID: 22265244 - DOI: 10.1016/j.jvir.2011.11.028

Oklu R, Stone JR, Albadawi H, Watkins MT

Extracellular Traps in Lipid-Rich Lesions of Carotid Atherosclerotic Plaques: Implications for Lipoprotein Retention and Lesion Progression. J Vasc Interv Radiol. 2014;25(4):631-4 - PMID: 24581730 - DOI: 10.1016/j.jvir.2013.12.567

Lee G, Kim DW, Smart AC, Horick NK, Eyler CE, Roberts HJ, Pathak P, Goyal L, Franses J, Heather JM, Hwang WL, Grassberger C, Klempner SJ, Drapek LC, Allen JN, Blaszkowsky LS, Parikh AR, Ryan DP, Clark JW, Hong TS, Wo JY

Hypofractionated Radiotherapy-Related Lymphopenia Is Associated With Worse Survival in Unresectable Intrahepatic Cholangiocarcinoma. Am J Clin Oncol. 2024;47(8):373-382 - PMID: 38767086 - PMCID: PMC12413688 - DOI: 10.1097/COC.0000000000001108

Ssedyabane F, Niyonzima N, Nambi Najjuma J, Birungi A, Atwine R, Tusubira D, Randall TC, Castro CM, Lee H, Ngonzi J

Prevalence of cervical intraepithelial lesions and associated factors among women attending a cervical cancer clinic in Western Uganda; results based on Pap smear cytology. SAGE Open Med. 2024;12:20503121241252265 - PMID: 38764539 - PMCID: PMC11100407 - DOI: 10.1177/20503121241252265

Losee M, Kavanaugh M, Liu M, Borges N, Haberman V, Ritzer J, Wolanski A, Bhimaniya S, Choudhury AD, Hyun H, Stoltenberg H, Kilbridge KL, Morgans A, Pomerantz M, Robertson M, Sakellis C, Shah H, Taplin ME, Wei XX, Ng T, Ravi P, Jacene H

Outcome of Subsequent Therapies After 177Lu-Vipivotide Tetraxetan for Metastatic Castrate-Resistant Prostate Cancer: A Tertiary Cancer Center Experience. Prostate. 2025;85(8):742-748 - PMID: 40103237 - DOI: 10.1002/pros.24880

Ssedyabane F, Niyonzima N, Ngonzi J, Najjuma JN, Namuli A, Okeny C, Nuwashaba D, Birungi A, Kajabwangu R, Randall TC, Castro CM, Lee H, Tusubira D

Diagnostic Accuracy of Serum P16ink4A and FOX-P3 Concentrations for Detection of Cervical Lesions Among Women Attending a Cervical Cancer Clinic in Western Uganda: A Case-Control Study. Anal Cell Pathol (Amst). 2025;2025:1931921 - PMID: 40365511 - PMCID: PMC12074841 - DOI: 10.1155/ancp/1931921

Iqbal S, Dai R, Adams R, An T, Sutphin P, Paranjape C, Arellano R, Thabet A, Kalva S, Weissleder R, Zhao S

Outcomes of Percutaneous Cystic Duct Stent (PCDS) Placement for Acute Cholecystitis. J Vasc Interv Radiol. 2025;37(1):107892 - PMID: 41161411 - DOI: 10.1016/j.jvir.2025.10.023

Zhao P, Kundu J, Blanton D, Rezaeeyazdi M, Oudin MJ, Miller MA, Meyer AS, Bencherif SA, Baranov PY, Young MJ, Carrier RL

Human Retinal Progenitor Cell (hRPC) Migration in Three-Dimensional (3D) Environments of Varying Stiffness and Composition. J Tissue Eng Regen Med. 2025;2025:9963972 - PMID: 41195017 - PMCID: PMC12585844 - DOI: 10.1155/term/9963972

Oh J, Bauer L, Walker SA, Weissleder R, Iqbal S

Next-Generation Approaches to Improve the Information Content of Interventional Radiology Biopsies. J Vasc Interv Radiol. 2025;36(12):1856-1861.e1 - PMID: 41276363 - DOI: 10.1016/j.jvir.2025.09.018

Monteiro JLGC, Takusagawa T, Vasconcelos BCE, Pai SI, McCain JP, Guastaldi FPS

A rabbit model to investigate temporomandibular joint osteochondral regeneration. Oral Surg Oral Med Oral Pathol Oral Radiol. 2021;134(1):20-27 - PMID: 35165066 - DOI: 10.1016/j.oooo.2021.12.004

Marshansky V

The V-ATPase a2-subunit as a putative endosomal pH-sensor. Biochem Soc T. 2007;35:1092-9 - PMID: 17956287 - DOI: 10.1042/BST0351092

Kelly KA, Reynolds F, Weissleder R, Josephson L

Fluorescein isothiocyanate-hapten immunoassay for determination of peptide-cell interactions. Anal Biochem. 2004;330(2):181-5 - PMID: 15203322 - DOI: 10.1016/j.ab.2004.02.035

Law B, Hsiao JK, Bugge TH, Weissleder R, Tung CH.

Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples Anal Biochem. 2005;338(1):151-158 - PMID: 15707946 - DOI: 10.1016/j.ab.2004.11.039

Laha M, Panizzi P, Nahrendorf M, Bock PE

Engineering streptokinase for generation of active site-labeled plasminogen analogs. Anal Biochem. 2011;415(2):105-15 - PMID: 21570944 - PMCID: PMC3114107 - DOI: 10.1016/j.ab.2011.04.025

Moss ML, Miller MA, Vujanovic N, Yoneyama T, Rasmussen FH

Fluorescent substrates for ADAM15 useful for assaying and high throughput screening. Anal Biochem. 2016;514:42-47 - PMID: 27637923 - DOI: 10.1016/j.ab.2016.09.010

Shtatland T, Guettler D, Kossodo M, Pivovarov M, Weissleder R

PepBank - a database of peptides based on sequence text mining and public peptide data sources. BMC Bioinformatics. 2007;8(1):280 - PMID: 17678535 - PMCID: PMC1976427 - DOI: 10.1186/1471-2105-8-280

Duchrow T, Shtatland T, Guettler D, Pivovarov M, Kramer S, Weissleder R

Enhancing navigation in biomedical databases by community voting and database-driven text classification. BMC Bioinformatics. 2009;10(1):317 - PMID: 19799796 - PMCID: PMC2768718 - DOI: 10.1186/1471-2105-10-317

Rabkin-Aikawa E, Mayer J, Schoen F

Heart valve regeneration. Adv Biochem Eng Biot. 2005;94:141-79 - PMID: 15915872 - DOI: 10.1007/b100003

Schima W, Saini S, Petersein J, Weissleder R, Harisinghani M, Mayo-Smith W, Hahn PF

MR imaging of the liver with Gd-BOPTA: quantitative analysis of T1-weighted images at two different doses J Magn Reson Imaging. 1999;10:80-3 - PMID: 10398981 - DOI: 10.1002/(sici)1522-2586(199907)10:1<80::aid-jmri11>3.0.co;2-s

Hofmann, B, Bogdanov A Jr, Marecos E, Ebert W, Semmler W, Weissleder R

Mechanism of gadophrin-2 accumulation in tumor necrosis J Magn Reson Imaging. 1999;9:336-41 - PMID: 10077034 - DOI: 10.1002/(sici)1522-2586(199902)9:2<336::aid-jmri28>3.0.co;2-3

Enochs WS, Harsh G, Hochberg F, Weissleder R

Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent J Magn Reson Imaging. 1999;9:228-32 - PMID: 10077018 - DOI: 10.1002/(sici)1522-2586(199902)9:2<228::aid-jmri12>3.0.co;2-k

Korosoglou G, Tang L, Kedziorek D, Cosby K, Gilson WD, Vonken EJ, Schar M, Sosnovik D, Kraitchman DL, Weiss RG, Weissleder R, Stuber M

Positive contrast MR-lymphography using inversion recovery with ON-resonant water suppression (IRON). J Magn Reson Imaging. 2008;27(5):1175-1180 - PMID: 18425827 - PMCID: PMC2740932 - DOI: 10.1002/jmri.21337

Nahrendorf M, Wiesmann F, Hiller K, Hu K, Waller C, Ruff J, Lanz T, Neubauer S, Haase A, Ertl G, Bauer W

Serial cine-magnetic resonance imaging of left ventricular remodeling after myocardial infarction in rats. J Magn Reson Imaging. 2001;14(5):547-55 - PMID: 11747006 - DOI: 10.1002/jmri.1218

Hamilton AM, Rogers KA, Belisle AJ, Ronald JA, Rutt BK, Weissleder R, Boughner DR

Early identification of aortic valve sclerosis using iron oxide enhanced MRI. J Magn Reson Imaging. 2010;31(1):110-6 - PMID: 20027578 - PMCID: PMC5638659 - DOI: 10.1002/jmri.22008

Reimer P, Bader A, Weissleder R

Preclinical assessment of hepatocyte-targeted MR contrast agents in stable human liver cell cultures. J Magn Reson Imaging. 1998;8(3):687-9 - PMID: 9626887 - DOI: 10.1002/jmri.1880080326

Moore A, Weissleder R, Bogdanov A

Uptake of dextran-coated monocrystalline iron oxides in tumor cells and macrophages. J Magn Reson Imaging. 1998;7(6):1140-5 - PMID: 9400860 - DOI: 10.1002/jmri.1880070629

Weissleder R, Cheng HC, Bogdanova A, Bogdanov A

Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging. 1997;7(1):258-63 - PMID: 9039625 - DOI: 10.1002/jmri.1880070140

Stiskal M, Schwickert HC, Demsar F, Roberts TP, Szolar D, Weissleder R, Brasch RC

Contrast enhancement in experimental radiation-induced liver injury: comparison of hepatocellular and reticuloendothelial particulate contrast agents. J Magn Reson Imaging. 1997;6(2):286-90 - PMID: 9132091 - DOI: 10.1002/jmri.1880060205

Reimer P, Saini S, Kwong KK, Cohen MS, Weissleder R, Brady TJ

Dynamic gadolinium-enhanced echo-planar MR imaging of the liver: effect of pulse sequence and dose on enhancement. J Magn Reson Imaging. 1994;4(3):331-5 - PMID: 8061430 - DOI: 10.1002/jmri.1880040318

Enochs WS, Weissleder R

MR imaging of the peripheral nervous system. J Magn Reson Imaging. 1994;4(3):251-7 - PMID: 7520307 - DOI: 10.1002/jmri.1880040306

Weissleder R, Wang YM, Papisov M, Bogdanov A, Schaffer B, Brady TJ, Wittenberg J

Polymeric contrast agents for MR imaging of adrenal glands. J Magn Reson Imaging. 1993;3(1):93-7 - PMID: 8428107 - DOI: 10.1002/jmri.1880030116

Reimer P, Kwong KK, Weisskoff R, Cohen MS, Brady TJ, Weissleder R

Dynamic signal intensity changes in liver with superparamagnetic MR contrast agents. J Magn Reson Imaging. 1992;2(2):177-81 - PMID: 1562768 - DOI: 10.1002/jmri.1880020210

Weissleder R, Papisov M

Pharmaceutical iron oxides for MR imaging J Magn Reson Imaging. 1992;4:1-6

Sosnovik DE, Dai G, Nahrendorf M, Rosen BR, Seethamraju R

Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm. J Magn Reson Imaging. 2007;26(2):279-87 - PMID: 17654729 - DOI: 10.1002/jmri.20966

Streif JU, Hiller KH, Waller C, Nahrendorf M, Wiesmann F, Bauer WR, Rommel E, Haase A

In vivo assessment of absolute perfusion in the murine skeletal muscle with spin labeling MRI. Magnetic resonance imaging. J Magn Reson Imaging. 2003;17(1):147-52 - PMID: 12500285 - DOI: 10.1002/jmri.10229

Gee MS, Harisinghani MG

MRI in patients with inflammatory bowel disease. J Magn Reson Imaging. 2011;33(3):527-534 - PMID: 21512607 - PMCID: PMC3078716 - DOI: 10.1002/jmri.22504

Osborn EA, Jaffer FA

Advances in molecular imaging of atherosclerotic vascular disease. Curr Opin Cardiol. 2008;23:620-8 - PMID: 18830079 - PMCID: PMC3984946 - DOI: 10.1097/HCO.0b013e328310fc7e

Vinegoni C, Karlsson M, Petersson M, Sunnerud H

Statistics of polarization-dependent loss in a recirculating loop. J Lightwave Technol. 2004;22:968-76

Wegmuller M, Oberson P, Guinnard O, Huttner B, Guinnard L, Vinegoni C, Gisin N

Distributed gain measurements in Er-doped fibers with high resolution and accuracy using an Optical Frequency Domain Reflectometer. J Lightwave Technol. 2000;18:2127-32

Low A, O'Donnell C, Kathiresan S, Everett B, Chae C, Shaw S, Ellinor P, MacRae C

Aging syndrome genes and premature coronary artery disease. BMC Med Genet. 2005;6:38 - PMID: 16262891 - PMCID: PMC1289285 - DOI: 10.1186/1471-2350-6-38

Neuwelt EA, Weissleder R, Nilaver G, Kroll RA, Roman-Goldstein S, Szumowski J, Pagel MA, Jones RS, Remsen LG, McCormick CI

Delivery of virus-sized iron oxide particles to rodent CNS neurons. Neurosurgery. 1994;34(4):777-84 - PMID: 8008188 - DOI: 10.1227/00006123-199404000-00048

Shum WW, Ruan YC, Da Silva N, Breton S

Establishment of Cell-Cell Crosstalk in the Epididymis: Control of Luminal Acidification. J Androl. 2011;32(6):576-86 - PMID: 21441423 - PMCID: PMC3753098 - DOI: 10.2164/jandrol.111.012971

Da Silva N, Shum WW, Breton S

Regulation of vacuolar proton pumping ATPase-dependent luminal acidification in the epididymis. Asian J Androl. 2007;9(4):476-82 - PMID: 17589784 - DOI: 10.1111/j.1745-7262.2007.00299.x

Da Silva N, Smith TB

Exploring the role of mononuclear phagocytes in the epididymis. Asian J Androl. 2015;17(4):591-6 - PMID: 25966624 - PMCID: PMC4492049 - DOI: 10.4103/1008-682X.153540

Breton S, Ruan YC, Park YJ, Kim B

Regulation of epithelial function, differentiation, and remodeling in the epididymis. Asian J Androl. 2015;18(1):3-9 - PMID: 26585699 - PMCID: PMC4736353 - DOI: 10.4103/1008-682X.165946

Zhu B, Jaffer F, Nztiachristos V, Weissleder R

Development of a near infrared fluorescence catheter: operating characteristics and feasibility for atherosclerotic plaque detection J Phys D Appl Phys. 2005;38:2701-2707

Bogdanov A, Petherick P, Marecos E, Weissleder R

In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation. Nucl Med Biol. 1997;24(8):739-42 - PMID: 9428599 - DOI: 10.1016/s0969-8051(97)00117-0

Ntziachristos V, Bremer C, Weissleder R

Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging Eur J Radiol. 2002;13:195-208 - PMID: 12541130 - DOI: 10.1007/s00330-002-1524-x

Bremer C, Ntziachristos V, Weissleder R

Optical-based molecular imaging: contrast agents and potential medical applications Eur J Radiol. 2002;13:231-43 - PMID: 12598985 - DOI: 10.1007/s00330-002-1610-0

Wunderbaldinger P, Bogdanov A, Weissleder R

New approaches for imaging in gene therapy Eur J Radiol. 2000;34:156-65 - PMID: 10927158 - DOI: 10.1016/s0720-048x(00)00196-0

Saksena MA, Saokar A, Harisinghani MG

Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging. Eur J Radiol. 2006;58(3):367-74 - PMID: 16472955 - DOI: 10.1016/j.ejrad.2005.12.041

Boland GW, Guimaraes AS, Mueller PR

Radiology report turnaround: expectations and solutions. Eur J Radiol. 2008;18(7):1326-8 - PMID: 18327594 - DOI: 10.1007/s00330-008-0905-1

Boland GW, Guimaraes AS, Mueller PR

The radiologist's conundrum: benefits and costs of increasing CT capacity and utilization. Eur J Radiol. 2008;19(1):9-11; discussion 12 - PMID: 18766347 - DOI: 10.1007/s00330-008-1159-7

Boland GW, Guimaraes AS, Mueller PR

The evolving radiology landscape: the importance of effective leadership. Eur J Radiol. 2009;19(10):2321-5 - PMID: 19471944 - DOI: 10.1007/s00330-009-1427-1

Weissleder R, Reimer P

Iron oxide based magnetopharmaceuticals for MR imaging Eur J Radiol. 1993;3:198-212

Agarwal S, Grajo JR, Fuentes-Orrego JM, Abtahi SM, Harisinghani MG, Saini S, Hahn PF

Distinguishing hemangiomas from metastases on liver MRI performed with gadoxetate disodium: Value of the extended washout sign. Eur J Radiol. 2016;85(3):635-40 - PMID: 26860678 - DOI: 10.1016/j.ejrad.2015.12.028

Rajendran R*, Ronald JA*, Ye T, Minqin R, Chen JW, Weissleder R, Rutt BK, Halliwell B, Watt F

Nuclear Microscopy: A Novel Technique for Quantitative Imaging of Gadolinium Distribution within Tissue Sections. Microsc Micoranal. 2009;15:338-44 - PMID: 19575834 - PMCID: PMC2802450 - DOI: 10.1017/S1431927609090813

Li Y, Zhao T, Liu B, Halaweish I, Mazitschek R, Duan X, Alam HB

Inhibition of histone deacetylase 6 improves long-term survival in a lethal septic model. J Trauma Acute Care Surg. 2015;78(2):378-85 - PMID: 25757125 - PMCID: PMC4357277 - DOI: 10.1097/TA.0000000000000510

Berteloot A, Malo C, Breton S, Brunette M

Fast sampling, rapid filtration apparatus: principal characteristics and validation from studies of D-glucose transport in human jejunal brush-border membrane vesicles. J Membr Biol. 1991;122(2):111-25 - PMID: 1895337 - DOI: 10.1007/BF01872635

Laprade R, Lapointe JY, Breton S, Duplain M, Cardinal J

Intracellular potassium activity in mammalian proximal tubule: effect of perturbations in transepithelial sodium transport. J Membr Biol. 1991;121(3):249-59 - PMID: 1865489 - DOI: 10.1007/BF01951558

Macri P, Breton S, Marsolais M, Lapointe J, Laprade R

Hypertonicity decreases basolateral K+ and Cl- conductances in rabbit proximal convoluted tubule. J Membr Biol. 1997;155(3):229-37 - PMID: 9050446 - DOI: 10.1007/s002329900175

Wollack JW, Monson BJ, Dozier JK, Dalluge JJ, Poss K, Hilderbrand SA, Distefano MD

Site-Specific Labeling of Proteins and Peptides with Trans-cyclooctene Containing Handles Capable of Tetrazine Ligation. Chem Biol Drug Des. 2014;84(2):140-7 - PMID: 24899362 - PMCID: PMC4107141 - DOI: 10.1111/cbdd.12303

Kevin Li-Chun H, Schob S, Zeller MW, Pulli B, Ali M, Wang C, Chiou TT, Tsang YM, Lee PS, Stossel TP, Chen JW

Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis. J Neuroimmunol. 2015;287:36-42 - PMID: 26439960 - PMCID: PMC4595933 - DOI: 10.1016/j.jneuroim.2015.08.006

Brown D

The Discovery of Water Channels (Aquaporins). Ann Nutr Metab. 2017;70 Suppl 1:37-42 - PMID: 28614812 - DOI: 10.1159/000463061

Breton S, Brown D

Novel Proinflammatory Function of Renal Intercalated Cells. Ann Nutr Metab. 2018;72 Suppl 2:11-16 - PMID: 29925073 - DOI: 10.1159/000488303

Brinkmann R, Koop N, Ozdemir M, Alt C, Sch

Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam. Laser Surg Med. 2003;32:252-64 - PMID: 12696092 - DOI: 10.1002/lsm.10150

Lin C, Weaver Y, Birngruber R, Fujimoto J, Puliafito CP

Intraocular microsurgery with a picosecond Nd:YAG laser. Laser Surg Med. 1995;15:44-53 - PMID: 7997047 - DOI: 10.1002/lsm.1900150107

Brinkmann R, H

Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen. Laser Surg Med. 2000;27(5):451-64 - PMID: 11126439 - DOI: 10.1002/1096-9101(2000)27:5<451::AID-LSM1006>3.0.CO;2-1

Chulroek T, Kordbacheh H, Wangcharoenrung D, Cattapan K, Heidari P, Harisinghani MG

Comparative accuracy of qualitative and quantitative 18F-FDG PET/CT analysis in detection of lymph node metastasis from anal cancer. Abdom Radiol (NY). 2019;44(3):828-835 - PMID: 30694369 - DOI: 10.1007/s00261-019-01907-6

Kordbacheh H, Baliyan V, Parakh A, Wojtkiewicz GR, Hedgire S, Harisinghani MG

Pictorial review on abdominal applications of ferumoxytol in MR imaging. Abdom Radiol (NY). 2019;44(10):3273-3284 - PMID: 31378828 - DOI: 10.1007/s00261-019-02163-4

O'Shea A, Kilcoyne A, Hedgire SS, Harisinghani MG

Pelvic lymph nodes and pathways of disease spread in male pelvic malignancies. Abdom Radiol (NY). 2020;45(7):2198-2212 - PMID: 31673716 - DOI: 10.1007/s00261-019-02285-9

Atre ID, Eurboonyanun K, O'Shea A, Lahoud RM, Shih A, Kalva S, Harisinghani MG, Hedgire S

Predictors of transmural intestinal necrosis in patients presenting with acute mesenteric ischemia on computed tomography. Abdom Radiol (NY). 2020;47(5):1636-1643 - PMID: 32382818 - DOI: 10.1007/s00261-020-02558-8

Atre ID, Eurboonyanun K, Noda Y, Parakh A, O'Shea A, Lahoud RM, Sell NM, Kunitake H, Harisinghani MG

Utility of texture analysis on T2-weighted MR for differentiating tumor deposits from mesorectal nodes in rectal cancer patients, in a retrospective cohort. Abdom Radiol (NY). 2020;46(2):459-468 - PMID: 32700214 - DOI: 10.1007/s00261-020-02653-w

Lu X, Galarneau MM, Higgins JM, Wood DK

A microfluidic platform to study the effects of vascular architecture and oxygen gradients on sickle blood flow. Microcirculation. 2017;24(5):ePub - PMID: 28129479 - PMCID: PMC5505799 - DOI: 10.1111/micc.12357

Islam T, Harisinghani MG

Prostate cancer imaging: what the next decade holds. Expert Rev Med Devices. 2010;7(5):577-9 - PMID: 20822379 - DOI: 10.1586/erd.10.43

Kilcoyne A, Kaplan JL, Gee MS

Inflammatory bowel disease imaging: Current practice and future directions. World J Gastroenterol. 2016;22(3):917-32 - PMID: 26811637 - PMCID: PMC4716045 - DOI: 10.3748/wjg.v22.i3.917

Harisinghani MG, Saksena M, Ross RW, Tabatabaei S, Dahl D, McDougal S, Weissleder R

A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation. Urology. 2005;66(5):1066-71 - PMID: 16286125 - DOI: 10.1016/j.urology.2005.05.049

Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG

Pilot Study Evaluating Use of Lymphotrophic Nanoparticle-Enhanced Magnetic Resonance Imaging for Assessing Lymph Nodes in Renal Cell Cancer. Urology. 2008;71(4):708-12 - PMID: 18295316 - DOI: 10.1016/j.urology.2007.11.096

Pittet M, Speiser D, Valmori D, Rimoldi D, Lienard D, Lejeune F, Cerottini J, Romero P

Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients. Int Immunopharmacol. 2001;1:1235-47 - PMID: 11460305 - DOI: 10.1016/s1567-5769(01)00048-0

Simonova M, Weissleder R, Sergeyev N, Vilissova N, Bogdanov A Jr

Targeting of green fluorescent protein expression to the cell surface Biochem Bioph Res Co. 1999;262:638-42 - PMID: 10471377 - DOI: 10.1006/bbrc.1999.1251

Izawa A, Schatton T, Frank NY, Ueno T, Yamaura K, Pendse SS, Margaryan A, Grimm M, Gasser M, Waaga-Gasser AM, Sayegh MH, Frank MH

A novel in vivo regulatory role of P-glycoprotein in alloimmunity. Biochem Bioph Res Co. 2010;394(3):646-52 - PMID: 20230790 - PMCID: PMC3756468 - DOI: 10.1016/j.bbrc.2010.03.040

Krause K, Schumacher LY, Sachdeva UM

Advances in Imaging to Aid Segmentectomy for Lung Cancer. Surg Oncol Clin N Am. 2022;31(4):595-608 - PMID: 36243496 - DOI: 10.1016/j.soc.2022.06.003

Choi HK, Yessayan D, Choi HJ, Schellenberger E, Bogdanov A, Josephson L, Weissleder R, Ntziachristos V.

Quantitative analysis of chemotherapeutic effects in tumors using in vivo staining and correlative histology Cell Oncol. 2005;27(3):183-90 - PMID: 16037639 - PMCID: PMC4615174 - DOI: 10.1155/2005/791936

Schoepf U, Marecos EM, Melder RJ, Jain RK, Weissleder R

Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. Biotechniques. 1998;24(4):642-6, 648-51 - PMID: 9564539 - DOI: 10.2144/98244rr01

Hilderbrand SA, Weissleder R

One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes. Tetrahedron Lett. 2007;48(25):4383-4385 - PMID: 19834587 - PMCID: PMC2761723 - DOI: 10.1016/j.tetlet.2007.04.088

Pham W, Weissleder R, Tung CH

A practical approach for the preparation of monofunctional azulenyl squaraine dye. Tetrahedron Lett. 2003;44(20):3975-3978 - PMID: 20740053 - PMCID: PMC2926986 - DOI: 10.1016/S0040-4039(03)00819-0

Pham W, Weissleder R, Tung CH

Intermolecular [8+2] cycloaddition reactions of 2H-3-methoxycarbonylcyclohepta[b]furan-2-one with vinyl ethers: an approach to bicyclo[5.3.0]azulene derivatives. Tetrahedron Lett. 2002;43(1):19-20 - PMID: 20740048 - PMCID: PMC2926969 - DOI: 10.1016/S0040-4039(01)02061-5

Shao H, Yoon TJ, Liong M, Weissleder R, Lee H

Magnetic nanoparticles for biomedical NMR-based diagnostics Beilstein J Nanotechnol. 2010;1:142154 - PMID: 21977404 - PMCID: PMC3045933 - DOI: 10.3762/bjnano.1.17

Panchenko MP, Silva N, Stone JR

Up-regulation of a hydrogen peroxide-responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasia. Cardiovasc Pathol. 2008;18(3):167-72 - PMID: 18508286 - PMCID: PMC2723736 - DOI: 10.1016/j.carpath.2008.03.008

Rabkin E, Schoen F

Cardiovascular tissue engineering. Cardiovasc Pathol. 2002;11:305-17 - PMID: 12459430 - DOI: 10.1016/s1054-8807(02)00130-8

Mendelson K, Aikawa E, Mettler B, Sales V, Martin D, Mayer J, Schoen F

Healing and remodeling of bioengineered pulmonary artery patches implanted in sheep. Cardiovasc Pathol. 2007;16:277-82 - PMID: 17868878 - DOI: 10.1016/j.carpath.2007.03.008

Collins AB, Smith RN, Stone JR

Classification of amyloid deposits in diagnostic cardiac specimens by immunofluorescence. Cardiovasc Pathol. 2008;18(4):205-16 - PMID: 18619857 - DOI: 10.1016/j.carpath.2008.05.004

Stone JR, Basso C, Baandrup UT, Bruneval P, Butany J, Gallagher PJ, Halushka MK, Miller DV, Padera RF, Radio SJ, Sheppard MN, Suvarna K, Tan CD, Thiene G, van der Wal AC, Veinot JP

Recommendations for processing cardiovascular surgical pathology specimens: a consensus statement from the Standards and Definitions Committee of the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology. Cardiovasc Pathol. 2011;21(1):2-16 - PMID: 21353600 - DOI: 10.1016/j.carpath.2011.01.001

Leone O, Veinot JP, Angelini A, Baandrup UT, Basso C, Berry G, Bruneval P, Burke M, Butany J, Calabrese F, d'Amati G, Edwards WD, Fallon JT, Fishbein MC, Gallagher PJ, Halushka MK, McManus B, Pucci A, Rodriguez ER, Saffitz JE, Sheppard MN, Steenbergen C, Stone JR, Tan C, Thiene G, van der Wal AC, Winters GL

2011 Consensus statement on endomyocardial biopsy from the Association for European Cardiovascular Pathology and the Society for Cardiovascular Pathology. Cardiovasc Pathol. 2011;21(4):245-74 - PMID: 22137237 - DOI: 10.1016/j.carpath.2011.10.001

Siddiquee Z, Zane NA, Smith RN, Stone JR

Dense IgG4 plasma cell infiltrates associated with chronic infectious aortitis: implications for the diagnosis of IgG4-related disease. Cardiovasc Pathol. 2012;21(6):470-5 - PMID: 22406174 - DOI: 10.1016/j.carpath.2012.02.001

Wang H, Albadawi H, Siddiquee Z, Stone JM, Panchenko MP, Watkins MT, Stone JR

Altered vascular activation due to deficiency of the NADPH oxidase component p22(phox.) Cardiovasc Pathol. 2013;23(1):35-42 - PMID: 24035466 - DOI: 10.1016/j.carpath.2013.08.003

Stone JR

Novel prognostic tissue markers in congestive heart failure. Cardiovasc Pathol. 2014;24(2):65-70 - PMID: 25453729 - DOI: 10.1016/j.carpath.2014.07.010

Stone JR, Bruneval P, Angelini A, Bartoloni G, Basso C, Batoroeva L, Buja LM, Butany J, d'Amati G, Fallon JT, Gittenberger-de Groot AC, Gouveia RH, Halushka MK, Kelly KL, Kholova I, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Suvarna SK, Tan CD, Thiene G, van der Wal AC, Veinot JP

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. Cardiovasc Pathol. 2015;24(5):267-278 - PMID: 26051917 - DOI: 10.1016/j.carpath.2015.05.001

Halushka MK, Angelini A, Bartoloni G, Basso C, Batoroeva L, Bruneval P, Buja LM, Butany J, d'Amati G, Fallon JT, Gallagher PJ, Gittenberger-de Groot AC, Gouveia RH, Kholova I, Kelly KL, Leone O, Litovsky SH, Maleszewski JJ, Miller DV, Mitchell RN, Preston SD, Pucci A, Radio SJ, Rodriguez ER, Sheppard MN, Stone JR, Suvarna SK, Tan CD, Thiene G, Veinot JP, van der Wal AC

Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association For European Cardiovascular Pathology: II. Noninflammatory degenerative diseases - nomenclature and diagnostic criteria. Cardiovasc Pathol. 2016;25(3):247-257 - PMID: 27031798 - DOI: 10.1016/j.carpath.2016.03.002

Stats MA, Stone JR

Varying levels of small microcalcifications and macrophages in ATTR and AL cardiac amyloidosis: implications for utilizing nuclear medicine studies to subtype amyloidosis. Cardiovasc Pathol. 2016;25(5):413-417 - PMID: 27469499 - DOI: 10.1016/j.carpath.2016.07.001

Li Y, Stone JR

The impact of splenectomy on human coronary artery atherosclerosis and vascular macrophage distribution. Cardiovasc Pathol. 2016;25(6):453-460 - PMID: 27614166 - DOI: 10.1016/j.carpath.2016.08.001

Huck A, Pozdnyakova O, Brunner A, Higgins JM, Fathi AT, Hasserjian RP

Prior cytopenia predicts worse clinical outcome in acute myeloid leukemia. Leuk Res. 2015;39(10):1034-40 - PMID: 26220865 - PMCID: PMC5764101 - DOI: 10.1016/j.leukres.2015.06.012

Wei CL, Valvano JW, Feldman MD, Nahrendorf M, Peshock R, Pearce JA

Volume catheter parallel conductance varies between end-systole and end-diastole. IEEE T Biomed Eng. 2007;54(8):1480-9 - PMID: 17694869 - DOI: 10.1109/TBME.2007.890732

Framme C, Walter A, Berger L, Prahs P, Alt C, Theisen-Kunde D, Kowal J, Brinkmann R

Selective Retina Therapy in Acute and Chronic-Recurrent Central Serous Chorioretinopathy. Ophthalmologica. 2015;234(4):177-188 - PMID: 26368551 - DOI: 10.1159/000439188

Kim Y, Choi Y, Weissleder R, Tung CH

Membrane permeable esterase-activated fluorescent imaging probe. Bioorg Med Chem Lett. 2007;17(18):5054-7 - PMID: 17664067 - PMCID: PMC1995663 - DOI: 10.1016/j.bmcl.2007.07.026

Mazitschek R, Patel V, Wirth D, Clardy J

Development of a fluorescence polarization based assay for histone deacetylase ligand discovery. Bioorg Med Chem Lett. 2008;18(9):2809-12 - PMID: 18430569 - PMCID: PMC2408937 - DOI: 10.1016/j.bmcl.2008.04.007

Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L

A stabilized demethoxyviridin derivative inhibits PI3 kinase. Bioorg Med Chem Lett. 2009;19(15):4223-7 - PMID: 19523825 - PMCID: PMC2877487 - DOI: 10.1016/j.bmcl.2009.05.105

Martyn DC, Cortese JF, Tyndall E, Dick J, Mazitschek R, Munoz B, Clardy J

Antiplasmodial activity of piperazine sulfonamides. Bioorg Med Chem Lett. 2009;20(1):218-21 - PMID: 19914069 - DOI: 10.1016/j.bmcl.2009.10.130

Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J

Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines. Bioorg Med Chem Lett. 2009;20(1):228-31 - PMID: 19914064 - DOI: 10.1016/j.bmcl.2009.10.133

Ghosh B, Zhao WN, Reis SA, Patnaik D, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ

Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation. Bioorg Med Chem Lett. 2016;26(4):1265-71 - PMID: 26804233 - PMCID: PMC4753070 - DOI: 10.1016/j.bmcl.2016.01.022

Aldana-Masangkay GI, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Hsieh YT, Kim YM, Lomenick B, Okemoto K, Landaw EM, Wang D, Mazitschek R, Bradner JE, Sakamoto KM

Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells. Leuk Lymphoma. 2011;52(8):1544-55 - PMID: 21699378 - PMCID: PMC4113006 - DOI: 10.3109/10428194.2011.570821

Haase A, Rigosi E, Frasnelli E, Trona F, Tessarolo F, Vinegoni C, Anfora G, Vallortigara G, Antolini R

A multimodal approach for tracing lateralisation along the olfactory pathway in the honeybee through electrophysiological recordings, morpho-functional imaging, and behavioural studies. Eur Biophys J. 2011;40(11):1247-1258 - PMID: 21956452 - PMCID: PMC3366498 - DOI: 10.1007/s00249-011-0748-6

Chang SY, Lo CS, Zhao XP, Liao MC, Chenier I, Bouley R, Ingelfinger JR, Chan JS, Zhang SL

Overexpression of angiotensinogen downregulates aquaporin 1 expression via modulation of Nrf2-HO-1 pathway in renal proximal tubular cells of transgenic mice. J Renin Angiotensin Aldosterone Syst. 2016;17(3):ePub - PMID: 27638854 - PMCID: PMC5843896 - DOI: 10.1177/1470320316668737

Bolondi G, Garuti C, Corradini E, Zoller H, Vogel W, Finkenstedt A, Babitt JL, Lin HY, Pietrangelo A

Altered hepatic BMP signaling pathway in human HFE hemochromatosis. Blood Cells Mol Dis. 2010;45(4):308-12 - PMID: 20863724 - PMCID: PMC3295241 - DOI: 10.1016/j.bcmd.2010.08.010

Je KH, Ryu WS, Lee SK, Kim EJ, Kim JY, Jang HJ, Park JE, Nahrendorf M, Schellingerhout D, Kim DE

Green-channel autofluorescence imaging: A novel and sensitive technique to delineate infarcts. J Neurosci Methods. 2017;279:22-32 - PMID: 28104485 - DOI: 10.1016/j.jneumeth.2017.01.007

Breton S, Lisanti MP, Tyszkowski R, McLaughlin M, Brown D

Basolateral distribution of caveolin-1 in the kidney. Absence from H+-atpase-coated endocytic vesicles in intercalated cells. J Histochem Cytochem. 1998;46(2):205-14 - PMID: 9446827 - DOI: 10.1177/002215549804600209

Swirski F, D'Sa A, Kianpour S, Inman M, Stampfli M

Prolonged ovalbumin exposure attenuates airway hyperresponsiveness and T cell function in mice. Int Arch Allergy Imm. 2006;141(2):130-40 - PMID: 16864992 - DOI: 10.1159/000094715

Shen S, Ding W, Ahmed S, Hu R, Opalacz A, Roth S, You Z, Wojtkiewicz GR, Lim G, Chen L, Mao J, Chen JW, Zhang Y

Ultrasmall Superparamagnetic Iron Oxide Imaging Identifies Tissue and Nerve Inflammation in Pain Conditions. Pain Med. 2018;19(4):686-692 - PMID: 29177411 - PMCID: PMC6659016 - DOI: 10.1093/pm/pnx267

Ripoll J, Ntziachristos V.

Quantitative point source photoacoustic inversion formulas for scattering and absorbing media Hys Rev E Stat Nonlin Soft Matter Phys. 2005;71(3 Pt 1):031912 - PMID: 15903464 - DOI: 10.1103/PhysRevE.71.031912

Figueiredo JL, Siegel C, Nahrendorf M, Weissleder R

Intraoperative Near-Infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury. World J Surg. 2010;34 (2):336-343 - PMID: 20033407 - PMCID: PMC2809822 - DOI: 10.1007/s00268-009-0332-8

Figueiredo JL, Nahrendorf M, Vinegoni C, Weissleder R

Intraoperative Near-infrared Fluorescent Cholangiography (NIRFC) in Mouse Models of Bile Duct Injury: Reply. World J Surg. 2011;35(3):694-5 - PMID: 20645091 - DOI: 10.1007/s00268-010-0728-5

Teixeira GV, Chikota H, Teixeira T, Manfro G, Pai SI, Tufano RP

Incidence of malignancy in thyroid nodules determined to be follicular lesions of undetermined significance on fine-needle aspiration. World J Surg. 2012;36(1):69-74 - PMID: 22057754 - DOI: 10.1007/s00268-011-1336-8

Dodd CH, Hsu HC, Chu WJ, Yang P, Zhang HG, Mountz JD Jr, Zinn K, Forder J, Josephson L, Weissleder R, Mountz JM, Mountz JD

Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles J Immunol Methods. 2001;256:89-105 - PMID: 11516758 - DOI: 10.1016/s0022-1759(01)00433-1

Kuzmin A, Purans J, Cazzanelli E, Vinegoni C, Mariotto G

XRD, EXAFS and Raman spectroscopy studies of pure ground WO3 and mixed W1-xRexO3-y polycrystals J Appl Phys. 1998;84:5515-24

Keliher EJ, Reiner T, Thurber GM, Upadhyay R, Weissleder R

Efficient (18)F-Labeling of Synthetic Exendin-4 Analogues for Imaging Beta Cells. ChemistryOpen. 2012;1(4):177-183 - PMID: 23997998 - PMCID: PMC3758109 - DOI: 10.1002/open.201200014

Zeglis BM, Emmetiere F, Pillarsetty N, Weissleder R, Lewis JS, Reiner T

Building Blocks for the Construction of Bioorthogonally Reactive Peptides via Solid-Phase Peptide Synthesis. ChemistryOpen. 2014;3(2):48-53 - PMID: 24808990 - PMCID: PMC4000166 - DOI: 10.1002/open.201402000

Simonova M, Shtanko O, Sergeyev N, Weissleder R, Bogdanov A Jr

Engineering of technetium-99m-binding artificial receptors for imaging gene expression J Gene Med. 2003;5:1056-66 - PMID: 14661181 - DOI: 10.1002/jgm.448

Diaz-Gil D, Fintelmann FJ, Molaei S, Elmi A, Hedgire SS, Harisinghani MG

Prediction of 5-year survival in advanced-stage ovarian cancer patients based on computed tomography peritoneal carcinomatosis index. Abdom Radiol. 2016;41(11):2196-2202 - PMID: 27338731 - DOI: 10.1007/s00261-016-0817-5

Hassanzadeh E, Glazer DI, Dunne RM, Fennessy FM, Harisinghani MG, Tempany CM

Prostate imaging reporting and data system version 2 (PI-RADS v2): a pictorial review. Abdom Radiol. 2017;42(1):278-289 - PMID: 27522352 - PMCID: PMC5247306 - DOI: 10.1007/s00261-016-0871-z

Hedgire SS, Kudrimoti S, Oliveira IS, Nadkarni N, McDermott S, Hahn PF, Mino-Kenudson M, Harisinghani MG

Extranodal lymphomas of abdomen and pelvis: imaging findings and differential diagnosis. Abdom Radiol. 2017;42(4):1096-1112 - PMID: 27866240 - DOI: 10.1007/s00261-016-0964-8

Baron JM, Higgins JM, Dzik WH

A Revised Timeline for the Origin of Plasmodium falciparum as a Human Pathogen. J Mol Evol. 2011;73(5-6):297-304 - PMID: 22183792 - DOI: 10.1007/s00239-011-9476-x

Giorgis F, Pirri CF, Vinegoni C, Pavesi L

Radiative emission properties of a-SiN:H based alloys, nanometric multilayers and light emitting devices J Lumin. 1998;80:423-427

Kilcoyne A, Price MC, McDermott S, Harisinghani MG

Imaging on nodal staging of prostate cancer. Future Oncol. 2016;13(6):551-565 - PMID: 27785926 - DOI: 10.2217/fon-2016-0216

Kim YI, Lee C, Lee H, Park IJ

Extracellular vesicles in colorectal cancer. Ann Coloproctol. 2025;41(5):379-392 - PMID: 41158051 - PMCID: PMC12569783 - DOI: 10.3393/ac.2025.00745.0106

Ross R, Harisinghani M

New clinical imaging modalities in prostate cancer. Hematol Oncol Clin N. 2006;20(4):811-30 - PMID: 16861116 - DOI: 10.1016/j.hoc.2006.03.009

Eisner BH, Kurtz MP, Harisinghani MG

Evolving Role of Magnetic Resonance Imaging in Renal Cancer Imaging. J Endourol. 2010;24(5):707-11 - PMID: 20433369 - DOI: 10.1089/end.2009.0507

de la Rosette J, Ahmed H, Barentsz J, Johansen TB, Brausi M, Emberton M, Frauscher F, Greene D, Harisinghani M, Haustermans K, Heidenreich A, Kovacs G, Mason M, Montironi R, Mouraviev V, de Reijke T, Taneja S, Thuroff S, Tombal B, Trachtenberg J, Wijkstra H, Polascik T

Focal therapy in prostate cancer-report from a consensus panel. J Endourol. 2010;24(5):775-80 - PMID: 20477543 - DOI: 10.1089/end.2009.0596

Petersein J, Saini S, Weissleder R

Liver. II: Iron oxide-based reticuloendothelial contrast agents for MR imaging. Clinical review. Magn Reson Imaging. 1996;4(1):53-60 - PMID: 8673716

Gupta H, Weissleder R

Targeted contrast agents in MR imaging. Magn Reson Imaging. 1996;4(1):171-84 - PMID: 8673713

Bader A, Reimer P, Knop E, Boker K, Christians U, Weissleder R, Sewing KF

An organotypical in vitro model of the liver parenchyma for uptake studies of diagnostic MR receptor agents. Magn Reson Imaging. 1996;13(7):991-1002 - PMID: 8583878 - DOI: 10.1016/0730-725x(95)00053-j

Schaffer BK, Linker C, Papisov M, Tsai E, Nossiff N, Shibata T, Bogdanov A, Brady TJ, Weissleder R

MION-ASF: biokinetics of an MR receptor agent. Magn Reson Imaging. 1993;11(3):411-7 - PMID: 7685055 - DOI: 10.1016/0730-725x(93)90074-n

Chen MC, Tsang YM, Stark DD, Weissleder R, Saini S, Brandhorst J, White DL, Engelstad BL, Ferrucci JT

Hepatic metastases: rat models for imaging research. Magn Reson Imaging. 1989;7(1):1-8 - PMID: 2918813 - DOI: 10.1016/0730-725x(89)90318-4

Weissleder R, Stark DD, Elizondo G, Hahn PF, Compton C, Saini S, Wittenberg J, Ferrucci JT

MRI of hepatic lymphoma. Magn Reson Imaging. 1989;6(6):675-81 - PMID: 3062298 - DOI: 10.1016/0730-725x(88)90092-6

Weissleder R, Stark DD, Compton CC, Simeone JF, Ferrucci JT

Cholecystitis: diagnosis by MR imaging. Magn Reson Imaging. 1988;6(3):345-8 - PMID: 3398743 - DOI: 10.1016/0730-725x(88)90412-2

Pinciroli R, Mietto C, Piriyapatsom A, Chenelle CT, Thomas JG, Pirrone M, Bry L, Wojtkiewicz GR, Nahrendorf MP, Kacmarek RM, Berra L

Endotracheal Tubes Cleaned With a Novel Mechanism for Secretion Removal: A Randomized Controlled Clinical Study. Respir Care. 2016;61(11):1431-1439 - PMID: 27460104 - DOI: 10.4187/respcare.04363

Hedgire S, Krebill C, Wojtkiewicz G, Oliveira I, Ghoshhajra BB, Hoffmann U, Harisinghani MG

Ultrasmall superparamagnetic iron oxide nanoparticle uptake as noninvasive marker of aortic wall inflammation on MRI: proof of concept study. Br J Radiol. 2018;91(1092):20180461 - PMID: 30160173 - PMCID: PMC6319856 - DOI: 10.1259/bjr.20180461

Hedgire S, Kilcoyne A, Tonyushkin A, Mao Y, Uyeda JW, Gervais DA, Harisinghani MG

Effect of androgen deprivation and radiation therapy on MRI fiber tractography in prostate cancer: Can we assess treatment response on imaging? Br J Radiol. 2018;92(1093):20170170 - PMID: 30209952 - PMCID: PMC6435068 - DOI: 10.1259/bjr.20170170

Cazzanelli E, Vinegoni C, Mariotto G, Kuzmin A, Purans J

Raman and XRD spectroscopic investigations of polymorphism in tungsten trioxide powders Solid State Ionics. 1999;123:67-74

Zhu H, Alt C, Webb RH, Melki S, Kochevar IE

Corneal Crosslinking With Rose Bengal and Green Light: Efficacy and Safety Evaluation. Cornea. 2016;35(9):1234-41 - PMID: 27362877 - DOI: 10.1097/ICO.0000000000000916

Soeken TA, Zhu H, DeMartelaere S, Davies BW, Kim M, Wang HC, Aden J, Grimm R, Alt C, Kochevar IE, Johnson AJ

Sealing of Corneal Lacerations Using Photoactivated Rose Bengal Dye and Amniotic Membrane. Cornea. 2018;37(2):211-217 - PMID: 29140861 - DOI: 10.1097/ICO.0000000000001389

Cazzanelli E, Vinegoni C, Mariotto G, Kuzmin A, Purans J

Comparative Raman study of the monoclinic-to-tetragonal phase transition in tungsten trioxide WO3 at high temperature and upon hydrogen insertion J Solid State Chem. 1999;143:24-32

Petersson M, Vinegoni C, Sunnerud H, Karlsson M

Statistics of PMD in recirculating loops. IEEE Photonic Tech L. 2003;15:1543-5

Vinegoni C, Chen H, Leblanc M, Schinn G, Wegmulller M, Gisin N

Distributed measurements of chromatic dispersion and nonlinear coefficient in low PMD dispersion shifted fibers IEEE Photonic Tech L. 2003;15:739-40

Wegmuller M, Demma S, Vinegoni C, Gisin N

Emulator of first- and second-order polarization mode dispersion. IEEE Photonic Tech L. 2002;14:630-2

Vinegoni C, Wegmuller M, Gisin N

Measurements of the nonlinear coefficient of standard SMF,DSF, and DSC fibers using a self-aligned interferometer and a Faraday mirror IEEE Photonic Tech L. 2001;13:1337-9

Wegmuller M, Legre M, Oberson P, Guinnard O, Guinnard L, Vinegoni C, Gisin N

Analysis of the polarization evolution in a ribbon cable using high resolution OFDR IEEE Photonic Tech L. 2000;13:145-7

Pauk M, Grgurevic L, Brkljacic J, Kufner V, Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt JL, Lin HY, Volarevic S, Vukicevic S

Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice. Int Orthop. 2014;39(1):161-172 - PMID: 25300398 - DOI: 10.1007/s00264-014-2550-4

Ueno T, Ikeda T, Ikeda K, Taniuchi H, Suda S, Yeung MY, Matsuno N

HMGB-1 as a Useful Prognostic Biomarker in Sepsis-Induced Organ Failure in Patients Undergoing PMX-DHP. J Surg Res. 2009;171(1):183-90 - PMID: 20338589 - DOI: 10.1016/j.jss.2009.11.708

Zhao T, Li Y, Liu B, Halaweish I, Mazitschek R, Alam HB

Selective inhibition of histone deacetylase 6 alters the composition of circulating blood cells in a lethal septic model. J Surg Res. 2014;190(2):647-54 - PMID: 24613069 - PMCID: PMC4267528 - DOI: 10.1016/j.jss.2014.01.056

Zhao Y, Zhou P, Liu B, Bambakidis T, Mazitschek R, Alam HB, Li Y

Protective effect of suberoylanilide hydroxamic acid against lipopolysaccharide-induced liver damage in rodents. J Surg Res. 2014;194(2):544-550 - PMID: 25479907 - PMCID: PMC4361238 - DOI: 10.1016/j.jss.2014.10.056

Erdem SS, Sazonova IY, Hara T, Jaffer FA, McCarthy JR

Detection and treatment of intravascular thrombi with magnetofluorescent nanoparticles. Method Enzymol. 2012;508:191-209 - PMID: 22449927 - DOI: 10.1016/B978-0-12-391860-4.00010-0

Lo Gullo R, Mishra S, Lira DA, Padole A, Otrakji A, Khawaja RD, Pourjabbar S, Singh S, Shepard JO, Digumarthy SR, Kalra MK, Stone JR

Quantification of interstitial fluid on whole body CT: comparison with whole body autopsy. Forensic Sci Med Pathol. 2015;11(4):488-496 - PMID: 26541472 - DOI: 10.1007/s12024-015-9728-y

McCormack CA, Lo Gullo R, Kalra MK, Louissaint A, Stone JR

Reliability of body size measurements obtained at autopsy: impact on the pathologic assessment of the heart. Forensic Sci Med Pathol. 2016;12(2):139-45 - PMID: 27020890 - DOI: 10.1007/s12024-016-9773-1

Xia Z, Huang X, Zhou X, Sun Y, Ntziachristos V, Wong S.

Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation IEEE T Inf Technol B. 0;12:569-578

Ueno T, Omura T, Takahashi T, Matsumoto H, Takahashi Y, Kakita A, Yamashina S

Liver transplantation using liver grafts preserved under high pressure. Artif Organs. 2005;29(10):849-55 - PMID: 16185349 - DOI: 10.1111/j.1525-1594.2005.00139.x

Bruckner C, McCarthy JR, Daniell HW,

A spectroscopic and computational study of the singlet and triplet excited states of synthetic beta-functionalized chlorins Chem Phys. 2003;294:285-303

Ross R, Harisinghani M

Prostate cancer imaging-what the urologic oncologist needs to know. Radiol Clin North Am. 2006;44(5):711-22 - PMID: 17030222 - DOI: 10.1016/j.rcl.2006.07.002

Hedgire SS, Pargaonkar VK, Elmi A, Harisinghani AM, Harisinghani MG

Pelvic nodal imaging. Radiol Clin North Am. 2012;50(6):1111-25 - PMID: 23122041 - DOI: 10.1016/j.rcl.2012.08.002

Kim YR, Savellano MD, Weissleder R, Bogdanov A Jr

Steady-state and dynamic contrast MR imaging of human prostate cancer xenograft tumors: a comparative study Technol Cancer Res T. 2002;1:489-95 - PMID: 12625776 - DOI: 10.1177/153303460200100609

Vinegoni C, Cazzanelli M, Trivelli A, Lunney GJ, Mariotto G, Levy J

Morphological and optical characterization of GaN prepared by pulsed laser ablation Surf Coat Tech. 2000;124:272-7

Yang A, Mitchell M, Di Capua J, Som A, Huang J, Weissleder R, Kalva S, Uppot R

Microwave Ablation for Resolution of Persistent Biloma Following Hepatectomy and Cholecystectomy: Case Report. Cardiovasc Intervent Radiol. 2021;45(3):387-390 - PMID: 34741197 - PMCID: PMC8570770 - DOI: 10.1007/s00270-021-02999-8

Kitson SL, Watters W, Moody TS, Chappell T, Mazitschek R

Nitrilase mediated mild hydrolysis of a carbon-14 nitrile for the radiosynthesis of 4-(7-hydroxycarbamoyl-[1-14 C-heptanoyl]-oxy)-benzoic acid methyl ester, [14 C]-SHP-141: a novel class I/II histone deacetylase (HDAC) inhibitor. J Labelled Comp Radiopharm. 2023;66(7-8):172-179 - PMID: 37186406 - DOI: 10.1002/jlcr.4026

Bogdanov AA Jr, Simonova M, Weissleder R

Engineering membrane proteins for nuclear medicine: applications for gene therapy and cell tracking Q J Nucl Med Mol IM. 2000;44:224-35 - PMID: 11105587

Saokar A, Braschi M, Harisinghani M

Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging. Abdom Imaging. 2006;31(6):660-7 - PMID: 16680506 - DOI: 10.1007/s00261-006-9006-2

Bouley R, Hawthorn G, Russo L, Lin HY, Ausiello D, Brown D

Aquaporin 2 (AQP2) and vasopressin receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in "endocytosis-resistant" membrane domains after vasopressin treatment. Abdom Imaging. 2005;:ePub - PMID: 16104839

Roedl JB, Blake MA, Holalkere NS, Mueller PR, Colen RR, Harisinghani MG

Lymph node staging in esophageal adenocarcinoma with PET-CT based on a visual analysis and based on metabolic parameters. Abdom Imaging. 2008;34(5):610-7 - PMID: 18830663 - DOI: 10.1007/s00261-008-9447-x

Quencer KB, Nimkin K, Mino-Kenudson M, Gee MS

Detecting active inflammation and fibrosis in pediatric Crohn's disease: prospective evaluation of MR-E and CT-E. Abdom Imaging. 2013;38(4):705-13 - PMID: 23361877 - PMCID: PMC4390174 - DOI: 10.1007/s00261-013-9981-z

Hedgire SS, Eberhardt SC, Borczuk R, McDermott S, Harisinghani MG

Interpretation and reporting multiparametric prostate MRI: a primer for residents and novices. Abdom Imaging. 2014;39(5):1036-51 - PMID: 24566965 - DOI: 10.1007/s00261-014-0097-x

Iyer VR, Hedgire SS, Hoskote SS, Borczuk D, Harisinghani MG

Retrospective cohort study of portacaval lymphadenopathy identified on multidetector CT and implications for follow-up. Abdom Imaging. 2015;40(6):1481-6 - PMID: 25516214 - DOI: 10.1007/s00261-014-0328-1

Lee DK, Nahrendorf M, Schellingerhout D, Kim DE

Will molecular optical imaging have clinically important roles in stroke management, and how? J Clin Neurol. 2010;6(1):10-8 - PMID: 20386638 - PMCID: PMC2851295 - DOI: 10.3988/jcn.2010.6.1.10

Weber GF, Swirski FK

Immunopathogenesis of abdominal sepsis. Langenbecks Arch Surg. 2014;399(1):1-9 - PMID: 24121723 - DOI: 10.1007/s00423-013-1129-7

Vieson MD, Gojmerac AM, Khan D, Dai R, van Duzer JH, Mazitschek R, Caudell DL, Liao X, Luo XM, Reilly CM

Treatment with a selective histone deacetylase 6 inhibitor decreases lupus nephritis in NZB/W mice. Histol Histopathol. 2017;32(12):1317-1332 - PMID: 28245046 - DOI: 10.14670/HH-11-885

Cazzanelli M, Vinegoni C, Lunney JG, O'Donnel KP, Middleton PG, Trager-Cowan C, Pavesi L

Luminescence properties of GaN thin films prepared by pulsed laser deposition Mat Sci Eng B-Solid. 1999;59:137-140

Harisinghani MG, Jhaveri KS, Weissleder R, Schima W, Saini S, Hahn PF, Mueller PR

MRI contrast agents for evaluating focal hepatic lesions Clin Radiol. 2001;56:714-25 - PMID: 11585393 - DOI: 10.1053/crad.2001.0764

Ross RW, Zietman AL, Xie W, Coen JJ, Dahl DM, Shipley WU, Kaufman DS, Islam T, Guimaraes AR, Weissleder R, Harisinghani M

Lymphotropic nanoparticle-enhanced magnetic resonance imaging (LNMRI) identifies occult lymph node metastases in prostate cancer patients prior to salvage radiation therapy. Clin Imaging. 2009;33(4):301-5 - PMID: 19559353 - DOI: 10.1016/j.clinimag.2009.01.013

Ventura E, Islam T, Gee MS, Mahmood U, Braschi M, Harisinghani MG

Detection of nodal metastatic disease in patients with non-small cell lung cancer: comparison of positron emission tomography (PET), contrast-enhanced computed tomography (CT), and combined PET-CT. Clin Imaging. 2010;34(1):20-28 - PMID: 20122515 - DOI: 10.1016/j.clinimag.2009.03.012

Saokar A, Islam T, Jantsch M, Saksena MA, Hahn PF, Harisinghani MG

Detection of lymph nodes in pelvic malignancies with computed tomography and magnetic resonance imaging. Clin Imaging. 2010;34(5):361-6 - PMID: 20813300 - DOI: 10.1016/j.clinimag.2009.07.004

Saokar A, Gee MS, Islam T, Mueller PR, Harisinghani MG

Appearance of primary lymphoid malignancies on lymphotropic nanoparticle-enhanced magnetic resonance imaging using ferumoxtran-10. Clin Imaging. 2010;34(6):448-52 - PMID: 21092874 - DOI: 10.1016/j.clinimag.2009.09.008

Hedgire SS, Elmi A, Nadkarni ND, Cao K, McDermott S, Harisinghani MG

Preoperative evaluation of perinephric fat invasion in patients with renal cell carcinoma: correlation with pathological findings. Clin Imaging. 2012;37(1):91-6 - PMID: 23206613 - DOI: 10.1016/j.clinimag.2012.03.005

Hedgire SS, Sainani NI, McDermott S, Hahn PF, Harisinghani MG

Mono-belly and beyond: spectrum of imaging manifestations of EBV infection in the abdomen. Clin Imaging. 2013;37(4):711-7 - PMID: 23317894 - DOI: 10.1016/j.clinimag.2012.10.003

Hedgire SS, Elmi A, Kambadakone AR, Yoon S, Blake M, Harisinghani MG

MDCT imaging of Alloderm biologic mesh spacers in the abdomen and pelvis - preliminary experience. Clin Imaging. 2014;38(3):279-82 - PMID: 24556330 - DOI: 10.1016/j.clinimag.2013.12.020

Hedgire SS, Tabatabaei S, McDermott S, Feldman A, Dahl DM, Harisinghani MG

Diversion ahead: imaging appearance of urinary diversions and reservoirs. Clin Imaging. 2014;38(4):418-427 - PMID: 24602415 - DOI: 10.1016/j.clinimag.2014.01.017

Silva AM, Ng TSC

Creating the freedom to thrive: Honoring the legacy of RSNA gold medalist, Deborah Levine, MD. Clin Imaging. 2023;106:110031 - PMID: 38128405 - DOI: 10.1016/j.clinimag.2023.110031

Blythe JA, Ng TSC

Ethical principles for practice building in the era of targeted radioligand therapy. Clin Imaging. 2024;116:110334 - PMID: 39488932 - DOI: 10.1016/j.clinimag.2024.110334

Rho S, Fialkowski KP, Harrington SG, Kako B, Zeman MN, Hyun H, Robertson M, Ng TSC

Strategies to enhance recruitment in nuclear medicine: A path forward. Clin Imaging. 2025;125:110572 - PMID: 40752450 - DOI: 10.1016/j.clinimag.2025.110572

Deffler C, Sedeh AE, Leitman E, Ng TSC, Chow DZ, Mahmood U, Heidari P, Mercaldo N, Esfahani SA

The role of PSMA PET/CT in identifying benign and malignant intracranial lesions in patients with prostate cancer. Clin Imaging. 2025;128:110620 - PMID: 40973568 - DOI: 10.1016/j.clinimag.2025.110620

Kako B, Strand ET, White MM, Carroll C, Seaman K, McCullough S, O'Shea A, Kaiser JA, Stanford L, Esfahani SA, Mahmood U, Heidari P, Ng TSC

Design and implementation of a patient management system for coordination of theranostics care at a major referral center. Clin Imaging. 2025;129:110673 - PMID: 41265114 - DOI: 10.1016/j.clinimag.2025.110673

Johnson J, Swirski F, Gajewska B, Wiley R, Fattouh R, Pacitto S, Wong J, Stampfli M, Jordana M

Divergent immune responses to house dust mite lead to distinct structural-functional phenotypes. Am J Physiol-Lung C. 2007;293:L730-9 - PMID: 17586699 - DOI: 10.1152/ajplung.00056.2007

Vinegoni C, Wegmuller M, Huttner B, Gisin N

Measurement of nonlinear polarization rotation in high birefringence optical fibers at telecom wavelength. 2000;2;314-184 J Opt A-Pure Appl Opt . 2000;2:314-184

Grimm J, Wunder A.

Current state of molecular imaging research Rofo-Fortschr Rontg. 2005;177(3):326-37 - PMID: 15719293 - DOI: 10.1055/s-2005-857946

Samir AE, Allegretti AS, Zhu Q, Dhyani M, Anvari A, Sullivan DA, Trottier CA, Dougherty S, Williams WW, Babitt JL, Wenger J, Thadhani RI, Lin HY

Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys. BMC Nephrol. 2015;16(1):119 - PMID: 26227484 - PMCID: PMC4521488 - DOI: 10.1186/s12882-015-0120-7

Gao M, Lewis G, Turner GM, Soubret A, Ntziachristos V.

Effects of background fluorescence in fluorescence molecular tomography Appl Optics. 2005;44(26):5468-74 - PMID: 16161661 - DOI: 10.1364/ao.44.005468

Faris GW, Ntziachristos V, Rector DM, Wang L

Topics in Biomedical Optics:introduction. Appl Optics. 2007;46(10):1595-6 - PMID: 17356600

Hooper BA, Domankevitz Y, Lin CP, Anderson RR

Precise, controlled laser delivery with evanescent optical waves. Appl Optics. 1999;38(25):5511-7 - PMID: 18324060 - DOI: 10.1364/ao.38.005511

Cazzanelli E, Mariotto G, Vinegoni C, Kuzmin A, Purans J

Color centers and polymorphism in pure and WO3 and mixed ReO3-WO3 powders. Ionics 2000;5;335-44 Ionics. 2000;5:335-44

Ryu WS, Schellingerhout D, Jeong SW, Nahrendorf M, Kim DE

Association between Serum Lipid Profiles and Early Neurological Deterioration in Acute Ischemic Stroke. J Stroke Cerebrovasc Dis. 2016;25(8):2024-30 - PMID: 27256172 - DOI: 10.1016/j.jstrokecerebrovasdis.2016.05.009

Ryu WS, Bae EK, Park SH, Jeong SW, Schellingerhout D, Nahrendorf M, Kim DE

Increased Left Ventricular Filling Pressure and Arterial Occlusion in Stroke Related to Atrial Fibrillation. J Stroke Cerebrovasc Dis. 2018;27(5):1275-1282 - PMID: 29310958 - DOI: 10.1016/j.jstrokecerebrovasdis.2017.12.009

Winkler DA, Burden FR, Yan B, Weissleder R, Tassa C, Shaw S, Epa VC

Modelling and predicting the biological effects of nanomaterials. SAR QSAR Environ Res. 2014;25(2):161-72 - PMID: 24625316 - DOI: 10.1080/1062936X.2013.874367

Graves EE, Culver JP, Ripoll J, Weissleder R, Ntziachristos V

Singular-value analysis and optimization of experimental parameters in fluorescence molecular tomography J Opt Soc Am A . 2004;21(2):231-41 - PMID: 14763766 - DOI: 10.1364/josaa.21.000231

Ong CS, Reinertsen E, Moonsamy P, Young K, Song S, Axtell AL, Wolfe SB, Mohan N, Jassar AS, Aguirre AD, Sundt TM

Late onset atrial fibrillation in patients undergoing surgical aortic valve replacement. J Card Surg. 2021;37(2):285-289 - PMID: 34699088 - DOI: 10.1111/jocs.16093

Linnoila JJ

Imaging in Autoimmune Neurology. Semin Neurol. 2018;38(3):371-378 - PMID: 30011416 - DOI: 10.1055/s-0038-1660476

Bradshaw MJ, Linnoila JJ

An Overview of Autoimmune and Paraneoplastic Encephalitides. Semin Neurol. 2018;38(3):330-343 - PMID: 30011413 - DOI: 10.1055/s-0038-1660821

van der Laan AM, Nahrendorf M, Piek JJ

Republished: Healing and adverse remodelling after acute myocardial infarction: role of the cellular immune response. Postgrad Med J. 2013;89(1047):52-8 - PMID: 23257717 - DOI: 10.1136/postgradmedj-2012-301623rep

Dip PV, Saw WG, Roessle M, Marshansky V, Grüber G

Solution structure of subunit a, a (104-363), of the Saccharomyces cerevisiae V-ATPase and the importance of its C-terminus in structure formation. J Bioenerg Biomembr. 2012;44(3):341-50 - PMID: 22562380 - DOI: 10.1007/s10863-012-9442-3

Coutinho AC, Krishnaraj A, Pires CE, Bittencourt LK, Guimaraes AR

Pelvic applications of diffusion magnetic resonance images. Magn Reson Imaging Clin N Am. 2011;19(1):133-57 - PMID: 21129639 - DOI: 10.1016/j.mric.2010.10.003

Harisinghani MG

The male pelvis. Magn Reson Imaging Clin N Am. 2014;22(2):xi - PMID: 24792681 - DOI: 10.1016/j.mric.2014.02.001

Sheth RA, Bittencourt LK, Guimaraes AR

Diffusion-Weighted Imaging of the Male Pelvis. Magn Reson Imaging Clin N Am. 2014;22(2):145-163 - PMID: 24792675 - DOI: 10.1016/j.mric.2014.01.003

Parsi S, Zhu C, Motlagh NJ, Kim D, Küllenberg EG, Kim HH, Gillani RL, Chen JW

Basic Science of Neuroinflammation and Involvement of the Inflammatory Response in Disorders of the Nervous System. Magn Reson Imaging Clin N Am. 2024;32(2):375-384 - PMID: 38555147 - PMCID: PMC10987041 - DOI: 10.1016/j.mric.2024.01.003

Tan W, Vinegoni C, Norman J, Desai T, Boppart S

Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Techniq. 2007;70(4):361-71 - PMID: 17262787 - DOI: 10.1002/jemt.20420

Harisinghani MG, Saini S, Weissleder R, Rubin D, deLange E, Harms S, Weinreb J, Small W, Sukerkar A, Brown JJ, Zelch J, Lucas M, Morris M, Hahn PF

Splenic imaging with ultrasmall superparamagnetic iron oxide ferumoxtran-10 (AMI-7227): preliminary observations J Comput Assist Tomogr. 2001;25:770-6 - PMID: 11584239 - DOI: 10.1097/00004728-200109000-00017

Li CS, Harisinghani MG, Lin WC, Braschi M, Hahn PF, Mueller PR

Enhancement Characteristics of Ultrasmall Superparamagnetic Iron Oxide Particle Within the Prostate Gland in Patients With Primary Prostate Cancer. J Comput Assist Tomogr. 2008;32:523-528 - PMID: 18664836 - DOI: 10.1097/RCT.0b013e318136e194

Prakash P, Kalra MK, Stone JR, Shepard JA, Digumarthy SR

Imaging findings of pericardial metastasis on chest computed tomography. J Comput Assist Tomogr. 2010;34(4):554-8 - PMID: 20657224 - DOI: 10.1097/RCT.0b013e3181d77d7e

Shenoy-Bhangle A, Nimkin K, Gee MS

Pediatric imaging: Current and emerging techniques. J Postgrad Med. 2010;56(2):98-102 - PMID: 20622388 - DOI: 10.4103/0022-3859.65273

Sanghvi D, Harisinghani MG

Modalities in modern radiology: A synopsis. J Postgrad Med. 2010;56(2):85-7 - PMID: 20622386 - DOI: 10.4103/0022-3859.65282

Ueno T, Sugino M, Nemoto H, Shoji H, Kakita A, Watanabe M

Effect over time of endotoxin adsorption therapy in sepsis. Ther Apher Dial. 2005;9(2):128-36 - PMID: 15828924 - DOI: 10.1111/j.1774-9987.2005.00230.x

Minami Y, Wang Z, Aguirre AD, Lee S, Uemura S, Soeda T, Vergallo R, Raffel OC, Barlis P, Itoh T, Lee H, Fujimoto J, Jang IK

Quantitative analysis of the side-branch orifice after bifurcation stenting using en-face processing of OCT images: a comparison between Xience V and Resolute Integrity stents. Coron Artery Dis. 2016;27(1):19-28 - PMID: 26554662 - PMCID: PMC4679565 - DOI: 10.1097/MCA.0000000000000319

Wang Z, Cho YS, Soeda T, Minami Y, Xing L, Jia H, Aguirre A, Vergallo R, Lee H, Fujimoto JG, Yu B, Jang IK

Three-dimensional morphological response of lipid-rich coronary plaques to statin therapy: a serial optical coherence tomography study. Coron Artery Dis. 2016;27(5):350-6 - PMID: 27105047 - PMCID: PMC4912393 - DOI: 10.1097/MCA.0000000000000370

Yamamoto E, Xing L, Higuma T, Minami Y, Bryniarski K, Zanchin T, Wang Z, Aguirre AD, Lee H, Jang IK

Dynamic neointimal pattern after drug-eluting stent implantation defined by optical coherence tomography. Coron Artery Dis. 2017;28(7):557-563 - PMID: 28704243 - DOI: 10.1097/MCA.0000000000000534

Dev S, Babitt JL

Overview of iron metabolism in health and disease. Hemodial Int. 2017;21 Suppl 1:S6-S20 - PMID: 28296010 - PMCID: PMC5977983 - DOI: 10.1111/hdi.12542

Horner B, Ferguson K, Randolph M, Spencer J, Carlson A, Hirsh E, Lin CP, Butler P

In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036

Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE

In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036

Horner BM, Ferguson KK, Randolph MA, Spencer JA, Carlson AL, Hirsh EL, Lin CP, Butler PE

In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts. J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036

Vinegoni C, Wegmuller M, Huttner B, Gisin N

All optical switching in a highly birefringent and a standard telecom fiber using a Faraday mirror stabilization scheme. Opt Commun. 2000;182:314-18

Lee H, Purdon AM, Westervelt RM

Micromanipulation of biological systems with microelectromagnets IEEE T Magn. 0;40(4):2991 - 2993

Karaosmanoglu AD, Gee MS

Sonographic findings of an adrenal leiomyosarcoma. J Ultrasound Med. 2010;29(9):1369-73 - PMID: 20733196 - DOI: 10.7863/jum.2010.29.9.1369

Weissleder R, Elizondo G, Stark DD

Sonographic diagnosis of subclavian and internal jugular vein thrombosis. J Ultrasound Med. 1987;6(10):577-87 - PMID: 3316690 - DOI: 10.7863/jum.1987.6.10.577

Shon SM, Jang HJ, Schellingerhout D, Kim JY, Ryu WS, Lee SK, Kim J, Park JY, Oh JH, Kang JW, Je KH, Park JE, Kim K, Kwon IC, Lee J, Nahrendorf M, Park JH, Kim DE

Cytokine Response to Diet and Exercise Affects Atheromatous Matrix Metalloproteinase-2/9 Activity in Mice. Circ J. 2017;81(10):1528-1536 - PMID: 28883215 - DOI: 10.1253/circj.CJ-16-1196

Gee MS, Harisinghani MG, Tabatabaei S

Molecular imaging in urologic surgery. Urol Clin N Am. 2009;36(2):125-32 - PMID: 19406314 - DOI: 10.1016/j.ucl.2009.02.007

González RG, Copen WA, Schaefer PW, Lev MH, Pomerantz SR, Rapalino O, Chen JW, Hunter GJ, Romero JM, Buchbinder BR, Larvie M, Hirsch JA, Gupta R

The Massachusetts General Hospital acute stroke imaging algorithm: an experience and evidence based approach. J Neurointerv Surg. 2013;5 Suppl 1:i7-i12 - PMID: 23493340 - PMCID: PMC3623036 - DOI: 10.1136/neurintsurg-2013-010715

Oklu R, Deipolyi AR, Wicky S, Ergul E, Deik AA, Chen JW, Hirsch JA, Wojtkiewicz GR, Clish CB

Identification of small compound biomarkers of pituitary adenoma: a bilateral inferior petrosal sinus sampling study. J Neurointerv Surg. 2013;6(7):541-6 - PMID: 24005126 - DOI: 10.1136/neurintsurg-2013-010821

Hilderbrand SA

Labels and probes for live cell imaging: overview and selection guide. Methods Mol Biol. 2009;591:17-45 - PMID: 19957122 - DOI: 10.1007/978-1-60761-404-3_2

Shah K

In Vivo Imaging of the Dynamics of Different Variants of EGFR in Glioblastomas. Methods Mol Biol. 2010;680:153-164 - PMID: 21153380 - DOI: 10.1007/978-1-60761-901-7_11

Jaffer FA

Intravital Fluorescence Microscopic Molecular Imaging of Atherosclerosis. Methods Mol Biol. 2010;680:131-140 - PMID: 21153378 - PMCID: PMC3051165 - DOI: 10.1007/978-1-60761-901-7_9

Shah K

Imaging Fate of Stem Cells at a Cellular Resolution in the Brains of Mice. Methods Mol Biol. 2010;680:91-101 - PMID: 21153375 - DOI: 10.1007/978-1-60761-901-7_6

Haun JB, Yoon TJ, Lee H, Weissleder R

Molecular Detection of Biomarkers and Cells Using Magnetic Nanoparticles and Diagnostic Magnetic Resonance. Methods Mol Biol. 2011;726:33-49 - PMID: 21424441 - DOI: 10.1007/978-1-61779-052-2_3

Wu JW, Runnels JM, Lin CP

Intravital imaging of hematopoietic stem cells in the mouse skull. Methods Mol Biol. 2014;1185:247-65 - PMID: 25062634 - DOI: 10.1007/978-1-4939-1133-2_17

Brettman AD, Tan PH, Tran K, Shaw SY

Applying the Logic of Genetic Interaction to Discover Small Molecules That Functionally Interact with Human Disease Alleles. Methods Mol Biol. 2015;1263:15-27 - PMID: 25618333 - PMCID: PMC4357233 - DOI: 10.1007/978-1-4939-2269-7_2

Ullal AV, Weissleder R

Photocleavable DNA Barcoding Antibodies for Multiplexed Protein Analysis in Single Cells. Methods Mol Biol. 2015;1346:47-54 - PMID: 26542714 - DOI: 10.1007/978-1-4939-2987-0_4

Conrad C, Miller MA, Bartsch JW, Schlomann U, Lauffenburger DA

Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method. Methods Mol Biol. 2017;1574:243-253 - PMID: 28315256 - DOI: 10.1007/978-1-4939-6850-3_18

Im H, Yang K, Lee H, Castro CM

Characterization of Extracellular Vesicles by Surface Plasmon Resonance. Methods Mol Biol. 2017;1660:133-141 - PMID: 28828653 - DOI: 10.1007/978-1-4939-7253-1_11

Min J, Allen M, Castro CM, Lee H, Weissleder R, Im H

Computational Optics for Point-of-Care Breast Cancer Profiling. Methods Mol Biol. 2022;2393:153-162 - PMID: 34837178 - PMCID: PMC9283060 - DOI: 10.1007/978-1-0716-1803-5_8

Matvey DO, Ng TSC, Miller MA

Confocal Imaging of Single-Cell Signaling in Orthotopic Models of Ovarian Cancer. Methods Mol Biol. 2022;2424:295-315 - PMID: 34918302 - DOI: 10.1007/978-1-0716-1956-8_19

Wissmeyer G, Kassab MB, Kawamura Y, Aguirre AD, Jaffer FA

Intravital Microscopy in Atherosclerosis Research. Methods Mol Biol. 2022;2419:645-658 - PMID: 35237994 - PMCID: PMC9052099 - DOI: 10.1007/978-1-0716-1924-7_40

Haase C, Richter D, Lin CP

Laser Micromachining of Bone as a Tool for Studying Bone Marrow Biology. Methods Mol Biol. 2023;2567:163-180 - PMID: 36255701 - PMCID: PMC10287113 - DOI: 10.1007/978-1-0716-2679-5_11

Jeong MH, Son T, Im H

Plasmon-Enhanced Characterization of Single Extracellular Vesicles. Methods Mol Biol. 2023;2668:3-13 - PMID: 37140785 - PMCID: PMC10394726 - DOI: 10.1007/978-1-0716-3203-1_1

Higgins JM

Red Blood Cell Population Dynamics. Clin Lab Med. 2014;35(1):43-57 - PMID: 25676371 - PMCID: PMC4717490 - DOI: 10.1016/j.cll.2014.10.002

Bell DL, Stapleton CJ, Terry AR, Stone JR, Ogilvy CS

Clinical presentation and treatment considerations of a ruptured posterior spinal artery pseudoaneurysm. J Clin Neurosci. 2014;21(7):1273-6 - PMID: 24572933 - DOI: 10.1016/j.jocn.2014.01.002

Weissleder R, Stark DD

Magnetic resonance imaging of liver tumors. Semin Ultrasound CT MR. 1989;10(1):63-77 - PMID: 2560665

Dejesus Allison SO, Javitt MC, Glanc P, Andreotti RF, Bennett GL, Brown DL, Dubinsky T, Harisinghani MG, Harris RD, Mitchell DG, Pandharipande PV, Pannu HK, Podrasky AE, Shipp TD, Siegel CL, Simpson L, Wong-You-Cheong JJ, Zelop CM

ACR Appropriateness Criteria® Multiple Gestations. Ultrasound Q. 2012;28(2):149-155 - PMID: 22634795 - DOI: 10.1097/RUQ.0b013e31824bfc06

Podrasky AE, Javitt MC, Glanc P, Dubinsky T, Harisinghani MG, Harris RD, Khati NJ, Mitchell DG, Pandharipande PV, Pannu HK, Shipp TD, Siegel CL, Simpson L, Wall DJ, Wong-You-Cheong JJ, Zelop CM

ACR Appropriateness Criteria® Second and Third Trimester Bleeding. Ultrasound Q. 2013;29(4):293-301 - PMID: 24263752 - DOI: 10.1097/RUQ.0000000000000044

Malka R, Lerner B

Classification of fluorescence in-situ hybridization images using belief networks Pattern Recogn Lett. 2004;25(16):1777-85

Liang JS, Lee SP, Pulli B, Chen JW, Kao SC, Tsang YM, Hsieh KL

Microstructural Changes in Absence Seizure Children: A Diffusion Tensor Magnetic Resonance Imaging Study. Pediatr Neonatol. 2015;57(4):318-25 - PMID: 26750405 - DOI: 10.1016/j.pedneo.2015.10.003

Perugino CA, Wallace ZS, Meyersohn N, Oliveira G, Stone JR, Stone JH

Large vessel involvement by IgG4-related disease. Medicine (Baltimore). 2016;95(28):e3344 - PMID: 27428181 - PMCID: PMC4956774 - DOI: 10.1097/MD.0000000000003344

Schellingerhout D, Josephson L

Molecular imaging of cell-based therapies. Neuroimag Clin N Am.. 2004;14(2):331-42 - PMID: 15182822 - DOI: 10.1016/j.nic.2004.03.009

Chen J, Wasserman B

Vulnerable plaque imaging. Neuroimag Clin N Am.. 2005;15:609-21, xi - PMID: 16360592 - DOI: 10.1016/j.nic.2005.08.005

Ssedyabane F, Obuku EA, Namisango E, Ngonzi J, Castro CM, Lee H, Randall TC, Ocan M, Apunyo R, Annet Kinengyere A, Kajabwangu R, Tahirah Kisawe A, Nambi Najjuma J, Tusubira D, Niyonzima N

The diagnostic accuracy of serum and plasma microRNAs in detection of cervical intraepithelial neoplasia and cervical cancer: A systematic review and meta-analysis. Gynecol Oncol Rep. 2024;54:101424 - PMID: 38939506 - PMCID: PMC11208915 - DOI: 10.1016/j.gore.2024.101424

Berry NC, Sosnovik DE

Cardiomyocyte Death: Insights from Molecular and Microstructural Magnetic Resonance Imaging. Pediatr Cardiol. 2011;32(3):290-6 - PMID: 21298427 - PMCID: PMC3078825 - DOI: 10.1007/s00246-011-9894-y

Malka R, Rom-Kedar V

Bacteria-phagocyte dynamics, axiomatic modelling and mass-action kinetics. Math Biosci Eng. 2011;8(2):475-502 - PMID: 21631141 - DOI: 10.3934/mbe.2011.8.475

Vinegoni C, Razansky D, Figueiredo JL, Fexon L, Pivovarov M, Nahrendorf M, Ntziachristos V, Weissleder R

Born Normalization for Fluorescence Optical Projection Tomography for Whole Heart Imaging J Vis Exp. 2009;28:1389 - PMID: 19578329 - PMCID: PMC2794886 - DOI: 10.3791/1389

Vinegoni C, Razansky D, Pitsouli C, Perrimon N, Ntziachristos V, Weissleder R

Mesoscopic fluorescence tomography for in-vivo imaging of developing Drosophila. J Vis Exp. 2009;(30):pii:1510 - PMID: 19696720 - PMCID: PMC2736679 - DOI: 10.3791/1510

Tassa C, Liong M, Hilderbrand S, Sandler JE, Reiner T, Keliher EJ, Weissleder R, Shaw SY

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications. J Vis Exp. 2013;(79):e50772 - PMID: 24084440 - PMCID: PMC3924759 - DOI: 10.3791/50772

Park D, Spencer JA, Lin CP, Scadden DT

Sequential In vivo Imaging of Osteogenic Stem/Progenitor Cells During Fracture Repair. J Vis Exp. 2014;(87):ePub - PMID: 24894331 - PMCID: PMC4206246 - DOI: 10.3791/51289

Mackay DD, Huesmann GR, Wu RI, Stone JR, Pless ML

Giant Cell Arteritis Causing Symmetric Bilateral Posterior Circulation Infarcts. J Clin Rheumatol. 2013;19(7):393-6 - PMID: 24048110 - DOI: 10.1097/RHU.0b013e3182a6ffc1

Petropoulos AE, Schaffer BK, Cheney ML, Enochs S, Zimmer C, Weissleder R

MR imaging of neuronal transport in the guinea pig facial nerve: initial findings. Acta Otolaryngol. 1995;115(4):512-6 - PMID: 7572127 - DOI: 10.3109/00016489509139358

Rabkin E, Hoerstrup S, Aikawa M, Mayer J, Schoen F

Evolution of cell phenotype and extracellular matrix in tissue-engineered heart valves during in-vitro maturation and in-vivo remodeling. J Heart Valve Dis. 2002;11:308-14; discussion 314 - PMID: 12056720

Rabkin-Aikawa E, Farber M, Aikawa M, Schoen F

Dynamic and reversible changes of interstitial cell phenotype during remodeling of cardiac valves. J Heart Valve Dis. 2004;13:841-7 - PMID: 15473488

Vinegoni C, Wegmuller M, Gisin N

Determination of the nonlinear coefficient n2/Aeff using a self-aligned interferometer and a Faraday mirror. . 2000;36;886 Electronic Lett. 2000;36:886-87

Islam T, Harisinghani MG

Overview of nanoparticle use in cancer imaging. Cancer Biomark. 2009;5:61-7 - PMID: 19414922 - DOI: 10.3233/CBM-2009-0578

Islam T, Josephson L

Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles. Cancer Biomark. 2009;5(2):99-107 - PMID: 19414927 - DOI: 10.3233/CBM-2009-0615

Harisinghani MG

Nanoparticle enhanced imaging. Cancer Biomark. 2009;5(2):59 - PMID: 19414921 - DOI: 10.3233/CBM-2009-0614

Islam T, Wolf G

The pharmacokinetics of the lymphotropic nanoparticle MRI contrast agent ferumoxtran-10. Cancer Biomark. 2009;5(2):69-73 - PMID: 19414923 - DOI: 10.3233/CBM-2009-0579

Sakamoto I, Takahashi T, Ueno T, Kakita A, Hayashi I, Yamashina S

Regeneration of Schwann cells during extrinsic hepatic reinnervation following liver transplantation in rats. Transpl P. 2003;35(1):573-4 - PMID: 12591537 - DOI: 10.1016/s0041-1345(02)03809-5

Kim CF, Jackson EL, Kirsch DG, Grimm J, Shaw AT, Lane K, Kissil J, Olive KP, Sweet-Cordero A, Weissleder R, Jacks T

Mouse Models of Human Non-Small-Cell Lung Cancer: Raising the Bar. Cold Spring Harb Symp Quant Biol. 2005;70:241-250 - PMID: 16869760 - DOI: 10.1101/sqb.2005.70.037

Wu X, Rabkin-Aikawa E, Guleserian K, Perry T, Masuda Y, Sutherland F, Schoen F, Mayer J, Bischoff J

Tissue-engineered microvessels on three-dimensional biodegradable scaffolds using human endothelial progenitor cells. Am J Phys. 2004;287:H480-7 - PMID: 15277191 - DOI: 10.1152/ajpheart.01232.2003

Libby P, Nahrendorf M, Weissleder R

Molecular imaging of atherosclerosis: a progress report. Tex Heart I J. 2010;37(3):324-7 - PMID: 20548813 - PMCID: PMC2879214

Fradley MG, Thakuria JV, Collins AB, Moore SA, Stone JR

Direct Tissue Evaluation via Immunofluorescence: in the Diagnosis of Hereditary Transthyretin Cardiac Amyloidosis. Tex Heart I J. 2012;39(1):71-5 - PMID: 22412233 - PMCID: PMC3298917

Swirski FK

Monocyte recruitment and macrophage proliferation in atherosclerosis. Kardiol Pol. 2014;72(4):311-4 - PMID: 24526549 - DOI: 10.5603/KP.a2014.0021

Zeller M, Hunter AD, McCarthy JR, Capetta SH, Bruckner C

Crystal and molecular structure of [5,10,15,20-tetrakisphenyl-2-ethoxy-3-oxa-chlorinato]Ag(II). J Chem Crystallogr. 2005;35(12):935-42

Yoon TJ, Shao H, Weissleder R, Lee H

Oxidation Kinetics and Magnetic Properties of Elemental Iron Nanoparticles Part. Part. Syst. Charact. 2013;30:667–671 - PMID: 24077230 - PMCID: PMC3783348 - DOI: 10.1002/ppsc.201300013

Shaw SY, Wang JC

DNA knot formation in aqueous solutions J Knot Theor Ramif. 1994;3:287-294

Lerner B, Malka R

Investigation of the K2 algorithm in learning Bayesian network classifiers Appl Artificial Intelligence . 2011;25(1):74-96

Wunderbaldinger P, Weissleder R

[Experimental and clinical approaches to lymph node imaging] Radiologe. 2001;41:121-30 - PMID: 11253097 - DOI: 10.1007/s001170050954

Weissleder R

[Experimental radiology in the USA] Radiologe. 2001;41:115 - PMID: 11253095 - DOI: 10.1007/s001170050952

Hogemann D, Basilion JP, Weissleder R

[Molecular imaging in magnetic resonance tomography and nuclear medicine] Radiologe. 2001;41:116-20 - PMID: 11253096 - DOI: 10.1007/s001170050953

Bremer C, Ntziachristos V, Mahmood U, Tung CH, Weissleder R

[Progress in optical imaging] Radiologe. 2001;41:131-7 - PMID: 11253098 - DOI: 10.1007/s001170050955

Bremer C, Bogdanov AA, Weissleder R

[Imaging of angiogenesis] Radiologe. 2001;41:138-45 - PMID: 11253099 - DOI: 10.1007/s001170050956

Nahrendorf M, Weissleder R

Advances in cardiovascular medicine through molecular imaging. Radiologe. 2007;47(1):18-24 - PMID: 17187263 - DOI: 10.1007/s00117-006-1450-z

Grimm J, Kircher MF, Weissleder R

Cell tracking : Principles and applications. Radiologe. 2007;47(1):25-33 - PMID: 17187264 - DOI: 10.1007/s00117-006-1449-5

Weissleder R, Imhof H

Molecular imaging -a new emphasis in radiology Radiologe. 2007;47(1):6-7 - PMID: 17136404 - DOI: 10.1007/s00117-006-1447-7

Reimer P, Weissleder R

[Development and experimental use of receptor-specific MR contrast media] Radiologe. 1996;36(2):153-63 - PMID: 8867433 - DOI: 10.1007/s001170050053

Rummeny E, Weissleder R, Stark DD, Elizondo G, Ferrucci JT

[Magnetic resonance tomography of focal liver and spleen lesions. Experiences using ferrite, a new RES-specific MR contrast medium] Radiologe. 1988;28(8):380-6 - PMID: 3174975

Weissleder R, Galarza D, Garza MA

Lupus nephritis: Classification, clinical features and treatment Rev Invest Clin. 1987;39:263-276

Bogdanov AA Jr, Chen JW, Kang HW, Weissleder R.

Magnetic resonance signal amplification probes Ernst Schering Res Found Workshop. 2005;49:147-57 - PMID: 15524215 - DOI: 10.1007/3-540-26809-x_8

Sosnovik D, Weissleder R

Magnetic resonance and fluorescence based molecular imaging technologies. Prog Drug Res. 2005;62:83-115 - PMID: 16329255 - DOI: 10.1007/3-7643-7426-8_3

Tsourkas A, Weissleder R

Illuminating the dynamics of intracellular activity with Mech Chem Biosyst. 2004;1:133-45 - PMID: 16783939

Mahmood U, Upadhyay R

Current and Future Imaging Paradigms in Colorectal Cancer Seminars in Colon and Rectal Surgery. 2007;18(2):132-138 - PMID: 18516215 - PMCID: PMC2084349 - DOI: 10.1053/j.scrs.2007.03.007

Romero P, Pittet M, Valmori D, Speiser D, Cerundolo V, Lienard D, Lejeune F, Cerottini J

Immune monitoring in cancer immunotherapy. Ernst Schering Res Found Workshop. 2000;(30):75-97 - PMID: 10943317 - DOI: 10.1007/978-3-662-04183-3_5

Sosnovik DE

Molecular imaging in cardiovascular magnetic resonance imaging: current perspective and future potential. Top Magn Reson Imaging. 2008;19:59-68 - PMID: 18690161 - PMCID: PMC2597277 - DOI: 10.1097/RMR.0b013e318176c57b

Miyazaki T,

Biology of Cholesterol Lowering in Atherosclerotic Plaques Immunol Endocrine and Metabolic Agents. 0;8(2):105-115

Shah K

Imaging neural stem cell fate in mouse model of glioma. Curr Protoc Stem Cell Biol. 2009;Chapter 5:Unit5A.1 - PMID: 19306259 - DOI: 10.1002/9780470151808.sc05a01s8

Osborn EA, Jaffer FA

The year in molecular imaging. J Am Coll Cardiol Img. 2009;2:97-113 - PMID: 19356541 - PMCID: PMC4802868 - DOI: 10.1016/j.jcmg.2008.11.001

Marks DL, Vinegoni C, Bredfeldt J, Boppart SA

Nonlinear Interferometric Vibrational Imaging. efficient detection of Coherent Anti-Stokes Raman Scattering OPN Special Issue, Optics in 2005. 2005;16:23

Razansky D, Vinegoni C, Ntziachristos V

Unprecedented in vivo views at the mesoscopic scale Biooptics World. 2009;2 (4):22-25

Sosnovik DE

Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach Curr Cardiovasc Imaging Rep. 2009;2:33-39

Nahrendorf M, Keliher E, Panizzi P, Zhang H, Hembrador S, Figueiredo JL, Aikawa E, Kelly K, Libby P, Weissleder R

18F-4V for PET-CT Imaging of VCAM-1 Expression in Atherosclerosis J Am Coll Cardiol Img. 2009;2:1213-1222 - PMID: 19833312 - PMCID: PMC2773129 - DOI: 10.1016/j.jcmg.2009.04.016

Rusanescu G, Weissleder R, Aikawa E

Notch signaling in cardiovascular disease and calcification. Curr Cardiol Review. 2008;4(3):148-56 - PMID: 19936191 - PMCID: PMC2780816 - DOI: 10.2174/157340308785160552

Lu J, Liong M, Sherman S, Xia T, Kovochich M, Nel AE, Zink JI, Tamanoi F

Mesoporous Silica Nanoparticles for Cancer Therapy: Energy-Dependent Cellular Uptake and Delivery of Paclitaxel to Cancer Cells. Nanobiotechnology. 2007;3(2):89-95 - PMID: 19936038 - PMCID: PMC2779038 - DOI: 10.1007/s12030-008-9003-3

Sosnovik DE, Caravan P

Molecular MRI of Atherosclerotic Plaque With Targeted Contrast Agents. Curr Cardiovasc Imaging Rep. 2009;2(2):87-94 - PMID: 20019886 - PMCID: PMC2794433 - DOI: 10.1007/s12410-009-0012-y

Sosnovik DE

Molecular Imaging of Myocardial Injury: A Magnetofluorescent Approach. Curr Cardiovasc Imaging Rep. 2009;2(1):33-39 - PMID: 20090858 - PMCID: PMC2808047 - DOI: 10.1007/s12410-009-0005-x

Haun JB, Yoon TJ, Lee H, Weissleder R

Magnetic nanoparticle biosensors. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;2(3):291-304 - PMID: 20336708 - DOI: 10.1002/wnan.84

McCarthy JR

Nanomedicine and Cardiovascular Disease. Curr Cardiovasc Imaging Rep. 2010;3(1):42-49 - PMID: 20369034 - PMCID: PMC2848940 - DOI: 10.1007/s12410-009-9002-3

Huang S, Sosnovik DE

Molecular and Microstructural Imaging of the Myocardium. Curr Cardiovasc Imaging Rep. 2010;3(1):26-33 - PMID: 20689659 - PMCID: PMC2916196 - DOI: 10.1007/s12410-010-9007-y

Chen HH, Josephson L, Sosnovik DE

Imaging of apoptosis in the heart with nanoparticle technology. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683 - DOI: 10.1002/wnan.115

Mohr U, Weissleder R

[Lymph node diagnosis with imaging methods. An overview with special reference to recent developments in the area of MR contrast media] Z Lymphol. 1996;20(1):15-20 - PMID: 8768044

Frank H, Weissleder R, Papisov M

[Presentation and quantification of acute myocardial infarct using antibody-bound MR contrast medium] Z Kardiol. 1995;84(4):311-5 - PMID: 7785304

Weissleder R, Bogdanov A, Papisov M

Drug targeting in magnetic resonance imaging. Magn Reson Q. 1992;8(1):55-63 - PMID: 1567758

Josephson L, Groman E, Weissleder R

Contrast agents for magnetic resonance imaging of the liver. Targeted Diagn Ther. 1992;4:163-87 - PMID: 1797156

Weissleder R, Stark DD

Magnetic resonance imaging of the liver. Magn Reson Q. 1989;5(2):97-121 - PMID: 2701280

Riojas GE, Weissleder R, Gonzalez HG, Miguel MC, Riojas AE, Morantes JG, Perez LET

Physical principles of magnetic resonance imaging Rev Mex Radiol. 1989;43:3-12

Contag C, Weissleder R, Bachmann M, Fraser S

Appllications of In Vivo Molecular Imaging in Biology and Medicine Neoreviews. 2000;1:233-240

Contag C, Fraser S, Weissleder, R

Strategies in in vivo molecular imaging Neoreviews. 2000;1:225-232

Neuberger T, Greiser A, Nahrendorf M, Jakob PM, Faber C, Webb AG

23Na microscopy of the mouse heart in vivo using density-weighted chemical shift imaging. MAGMA. 2004;17(3-6):196-200 - PMID: 15580377 - DOI: 10.1007/s10334-004-0048-6

Hucker WJ, Jaffer FA

F-FDG PET Imaging of Atherosclerosis-A New Approach to Detect Inflamed, High-Risk Coronary Plaques? Curr Cardiovasc Imaging Rep. 2011;4(1):1-3 - PMID: 21297872 - PMCID: PMC3032349 - DOI: 10.1007/s12410-010-9054-4

Chen HH, Josephson L, Sosnovik DE

Imaging of apoptosis in the heart with nanoparticle technology. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2011;3(1):86-99 - PMID: 20945336 - PMCID: PMC3086683 - DOI: 10.1002/wnan.115

Beck JS, Marsolais M, N

Dibutyryl cyclic adenosine monophosphate stimulates the sodium pump in rabbit renal cortical tubules. Ren Physiol Biochem. 1995;18(1):21-6 - PMID: 7533315 - DOI: 10.1159/000173895

Brown D, Sabolic I, Breton S

Polarized expression of membrane proteins in renal epithelial cells: involvement of specialized transport vesicles and intracellular pathways. Adv Nephrol Necker Hosp. 1998;27:297-315 - PMID: 9408453

Breton S

The cellular physiology of carbonic anhydrases. JOP. 2001;2(4 Suppl):159-64 - PMID: 11875253

Breton S, Smith PJS, Brown D

Presence de cellules acidifiantes dans l'epididyme et le canal deferent: implication de la pompe a protons Medecine/Sciences. 1997;13:57-61

Oei T, Hedgire S, Harisinghani M

Advanced cross-sectional imaging techniques for the detection and characterization of renal masses Imaging Med. 2011;3 (2):207-218

Kamberov YG, Kim J, Mazitschek R, Kuo WP, Whitman M

Microarray profiling reveals the Integrated Stress Response is activated by Halofuginone in mammary epithelial cells. BMC Res Notes. 2011;4(1):381 - PMID: 21974968 - PMCID: PMC3197508 - DOI: 10.1186/1756-0500-4-381

Tekirian TL, Merriam DE, Marshansky V, Miller J, Crowley AC, Chan H, Ausiello D, Brown D, Buxbaum JD, Xia W, Wasco W

Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments. Brain Res Mol Brain Res. 2001;96(1-2):14-20 - PMID: 11731004 - DOI: 10.1016/s0169-328x(01)00250-9

Thomas S, Waterman P, Chen S, Marinelli B, Seaman M, Rodig S, Ross RW, Josephson L, Weissleder R, Kelly KA

Development of Secreted Protein and Acidic and Rich in Cysteine (SPARC) Targeted Nanoparticles for the Prognostic Molecular Imaging of Metastatic Prostate Cancer J Nanomedic Nanotechnol. 2011;2(4):112 - PMID: 22319675 - PMCID: PMC3273319 - DOI: 10.4172/2157-7439.1000112

Zettergren E, Vickers D, Runnels J, Lin CP, Niedre MJ

Validation of a device for fluorescence sensing of rare circulating cells with diffusive light in an optical flow phantom model. Conf Proc IEEE Eng Med Biol Soc. 2011;2011:486-9 - PMID: 22254354 - PMCID: PMC3555486 - DOI: 10.1109/IEMBS.2011.6090071

Kirkin V, Mazitschek R, Krishnan J, Steffen A, Waltenberger J, Pepper MS, Giannis A, Sleeman JP

Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2. Eur J Biochem. 2001;268(21):5530-40 - PMID: 11683876 - DOI: 10.1046/j.1432-1033.2001.02476.x

Lerner B, Malka R

Learning Bayesian Networks for Cytogenetic Image Classification ICPR. 2006;2:772-5

Lerner B, Malka R

Belief Networks for Cytogenetic Image Classification 23rd IEEE Convention of Electrical and Electronics Engineers in Israel. 2004;6(7):297-300

Malka R, Wolach B, Gavrieli R, Shochat E, Rom-Kedar V

Bi-stability of phagocyte-bacteria interaction: when do neutrophils win the battle with Staphylococcus Aureus? 44th Annual Scientific Meeting of the European Society for Clinical Investigation, Bari, Italy. 2010;:ePub

Rosenthal A, Jaffer FA, Ntziachristos V

Intravascular multispectral optoacoustic tomography of atherosclerosis: prospects and challenges. Imaging Med. 2012;4(3):299-310 - PMID: 23144663 - PMCID: PMC3493570 - DOI: 10.2217/iim.12.20

Yui N, Lu HJ, Bouley R, Brown D

AQP2 is necessary for vasopressin- and forskolin-mediated filamentous actin depolymerization in renal epithelial cells. Biol Open. 2011;1(2):101-8 - PMID: 23213402 - PMCID: PMC3507199 - DOI: 10.1242/bio.2011042

Vinegoni C, Lee S, Gorbatov R, Weissleder R

Motion compensation using a suctioning stabilizer for intravital microscopy Intravital. 2012;1:115-121 - PMID: 24086796 - PMCID: PMC3786172 - DOI: 10.4161/intv.23017

Alt C, Runnels J, Teo G, Lin C

In vivo tracking of hematopoietic cells in the retina of chimeric mice with a scanning laser ophthalmoscope Intravital. 2012;1:132-140

Hedgire SS, Oei TN, McDermott S, Cao K, Patel M Z, Harisinghani MG

Multiparametric magnetic resonance imaging of prostate cancer. Indian J Radiol Imaging. 2012;22(3):160-9 - PMID: 23599562 - PMCID: PMC3624737 - DOI: 10.4103/0971-3026.107176

Cortez-Retamozo V, Engblom C, Pittet MJ

Remote control of macrophage production by cancer. OncoImmunology. 2013;2(5):e24183 - PMID: 23762799 - PMCID: PMC3667905 - DOI: 10.4161/onci.24183

Phillips JA, Mortensen LJ, Ruiz JP, Sridharan R, Kumar S, Torres M, Sharma P, Lin CP, Karp JM, Hauschka PV

Advances in Single-cell Tracking of Mesenchymal Stem Cells (MSCs) During Musculoskeletal Regeneration. Orthop J Harv Med Sch. 2012;14:22-28 - PMID: 24244929 - PMCID: PMC3824625

Coffey SE, Giedt RJ, Weissleder R

Automated analysis of clonal cancer cells by intravital imaging. Intravital. 2013;2(3):ePub - PMID: 24349895 - PMCID: PMC3859690 - DOI: 10.4161/intv.26138

Schietinger A, Arina A, Liu RB, Wells S, Huang J, Engels B, Bindokas V, Bartkowiak T, Lee D, Herrmann A, Piston DW, Pittet MJ, Lin PC, Zal T, Schreiber H

Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer. OncoImmunology. 2013;2(11):e26677 - PMID: 24482750 - PMCID: PMC3895414 - DOI: 10.4161/onci.26677

Liu CL, Bernstein BE, Schreiber SL

Whole Genome Amplification by T7-Based Linear Amplification of DNA (TLAD): I. CIP Treatment of Samples and Tailing Reaction with Terminal Transferase. CSH Protoc. 2008;2008:pdb.prot5002 - PMID: 21356834 - DOI: 10.1101/pdb.prot5002

Baron JM, Dighe AS, Arnaout R, Balis UJ, Black-Schaffer WS, Carter AB, Henricks WH, Higgins JM, Jackson BR, Kim J, Klepeis VE, Le LP, Louis DN, Mandelker D, Mermel CH, Michaelson JS, Nagarajan R, Platt ME, Quinn AM, Rao L, Shirts BH, Gilbertson JR

The 2013 symposium on pathology data integration and clinical decision support and the current state of field. J Pathol Inform. 2014;5:2 - PMID: 24672737 - PMCID: PMC3952400 - DOI: 10.4103/2153-3539.126145

Da Silva N, Meyer-Monard S, Menot ML, Parrado A, Lebel A, Balitrand N, Fenaux P, Micléa JM, Rousselot P, Degos L, Dombret H, Chomienne C

Functional G-CSF pathways in t(8;21) leukemic cells allow for differentiation induction and degradation of AML1-ETO. Hematol J. 2002;1(5):316-28 - PMID: 11920209 - DOI: 10.1038/sj.thj.6200047

Shelley CS, Da Silva N, Teodoridis JM

During U937 monocytic differentiation repression of the CD43 gene promoter is mediated by the single-stranded DNA binding protein Pur alpha. Br J Haematol. 2001;115(1):159-66 - PMID: 11722429 - DOI: 10.1046/j.1365-2141.2001.03066.x

Shelley CS, Da Silva N, Georgakis A, Chomienne C, Arnaout MA

Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb. Genomics. 1998;49(2):334-6 - PMID: 9598326 - DOI: 10.1006/geno.1998.5232

Da Silva N, Meyer-Monard S, Menot ML, Degos L, Baruchel A, Dombret H, Chomienne C

G-CSF activates STAT pathways in Kasumi-1 myeloid leukemic cells with the t(8; 21) translocation: basis for potential therapeutic efficacy. Cytokines Cell Mol Ther. 1997;3(2):75-80 - PMID: 9287246

Ali M, Pulli B, Chen JW

Molecular imaging of macrophage enzyme activity in cardiac inflammation. Curr Cardiovasc Imaging Rep. 2014;7(4):9258 - PMID: 24729833 - PMCID: PMC3979571 - DOI: 10.1007/s12410-014-9258-0

Core AB, Canali S, Babitt JL

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis. Front Pharmacol. 2014;5:104 - PMID: 24860505 - PMCID: PMC4026703 - DOI: 10.3389/fphar.2014.00104

Wang CY, Meynard D, Lin HY

The role of TMPRSS6/matriptase-2 in iron regulation and anemia. Front Pharmacol. 2014;5:114 - PMID: 24966834 - PMCID: PMC4053654 - DOI: 10.3389/fphar.2014.00114

Ausiello D, Shaw S

Quantitative human phenotyping: the next frontier in medicine. Trans Am Clin Climatol Assoc. 2014;125:219-28 - PMID: 25125736 - PMCID: PMC4112685

Ananthakrishnan AN, Cagan A, Gainer VS, Cheng SC, Cai T, Szolovits P, Shaw SY, Churchill S, Karlson EW, Murphy SN, Kohane I, Liao KP

Higher plasma vitamin D is associated with reduced risk of Clostridium difficile infection in patients with inflammatory bowel diseases. Aliment Pharmacol Ther. 2014;39(10):1136-42 - PMID: 24641590 - PMCID: PMC4187206 - DOI: 10.1111/apt.12706

Mietto C, Pinciroli R, Piriyapatsom A, Thomas JG, Bry L, Delaney ML, Du Bois A, Truelove J, Ackman JB, Wojtkiewicz GR, Nahrendorf M, Kacmarek RM, Berra L

Tracheal Tube Obstruction in Mechanically Ventilated Patients Assessed by High-resolution Computed Tomography. Anesthesiology. 2014;121(6):1226-1235 - PMID: 25254903 - DOI: 10.1097/ALN.0000000000000455

Swirski FK

Inflammation and repair in the ischaemic myocardium. Hamostaseologie. 2014;35(1):34-6 - PMID: 25375277 - DOI: 10.5482/HAMO-14-09-0045

Arystarkhova E, Ralph DL, Liu YB, Bouley R, McDonough AA, Sweadner KJ

Paradoxical activation of the sodium chloride cotransporter (NCC) without hypertension in kidney deficient in a regulatory subunit of Na,K-ATPase, FXYD2. Physiol Rep. 2014;2(12):ePub - PMID: 25472608 - PMCID: PMC4332208 - DOI: 10.14814/phy2.12226

Alieva M, Ritsma L, Giedt RJ, Weissleder R, van Rheenen J

Imaging windows for long-term intravital imaging: general overview Intravital. 2014;3:2: e29917

Ecker J, Oehme I, Mazitschek R, Korshunov A, Kool M, Hielscher T, Kiss J, Selt F, Konrad C, Lodrini M, Deubzer HE, von Deimling A, Kulozik AE, Pfister SM, Witt O, Milde T

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma. Acta Neuropathol Commun. 2015;3(1):22 - PMID: 25853389 - PMCID: PMC4382927 - DOI: 10.1186/s40478-015-0201-7

Stone JR

Diagnostic Biopsies of the Native Heart. Surg Pathol Clin. 2012;5(2):401-16 - PMID: 26838110 - DOI: 10.1016/j.path.2012.04.004

Sager HB, Nahrendorf M

Inflammation: a trigger for acute coronary syndrome. Q J Nucl Med Mol Imaging. 2016;60(3):185-193 - PMID: 27273431

Clardy SM, Kohler RH, Vinegoni C, Iwamoto Y, Keliher EJ, Weissleder R

Two-photon imaging of pancreatic beta cells in real time in vivo Technology. 2016;4(2):130-134

Swirski FK, Nahrendorf M, Libby P

Mechanisms of Myeloid Cell Modulation of Atherosclerosis. Microbiol Spectr. 2016;4(4):ePub - PMID: 27726819 - DOI: 10.1128/microbiolspec.MCHD-0026-2015

Kim J, Park JE, Nahrendorf M, Kim DE

Direct Thrombus Imaging in Stroke. J Stroke. 2016;18(3):286-296 - PMID: 27733029 - PMCID: PMC5066439 - DOI: 10.5853/jos.2016.00906

Im H, Lee H, Castro CM

Challenges influencing next generation technologies for precision medicine. Expert Rev Precis Med Drug Dev. 2016;1(2):121-123 - PMID: 28008420 - PMCID: PMC5166706 - DOI: 10.1080/23808993.2016.1165073

Christensen HL, Păunescu TG, Matchkov V, Barbuskaite D, Brown D, Damkier HH, Praetorius J

The V-ATPase is expressed in the choroid plexus and mediates cAMP-induced intracellular pH alterations. Physiol Rep. 2017;5(1):ePub - PMID: 28053225 - PMCID: PMC5256157 - DOI: 10.14814/phy2.13072

Miller M, Feng X, Li G, Rabitz H

Nonlinear bionetwork structure inference using the random sampling-high dimensional model representation (RS-HDMR) algorithm. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:6412-5 - PMID: 19964421 - DOI: 10.1109/IEMBS.2009.5333798

Im H, Wittenberg NJ, Lindquist NC, Oh SH

Atomic layer deposition (ALD): A versatile technique for plasmonics and nanobiotechnology. J Mater Res. 2012;27(4):663-671 - PMID: 22865951 - PMCID: PMC3410655 - DOI: 10.1557/jmr.2011.434

Bantz KC, Meyer AF, Wittenberg NJ, Im H, Kurtuluş O, Lee SH, Lindquist NC, Oh SH, Haynes CL

Recent progress in SERS biosensing. Phys Chem Chem Phys. 2011;13(24):11551-67 - PMID: 21509385 - PMCID: PMC3156086 - DOI: 10.1039/c0cp01841d

Lesuffleur A, Lim KS, Lindquist NC, Im H, Warrington AE, Rodriguez M, Oh SH

Plasmonic nanohole arrays for label-free kinetic biosensing in a lipid membrane environment. Conf Proc IEEE Eng Med Biol Soc. 2009;2009:1481-4 - PMID: 19963504 - DOI: 10.1109/IEMBS.2009.5332429

Huang X, Im H, Yarimaga O, Kim J, Jang D, Lee D, Kim H, Choi Y

Electrochemical behavior of needle-like and forest-like single-walled carbon nanotube electrodes J Electroanal Chem. 2006;594(1):27-34

Huang X, Choi Y, Im H, Yarimaga O, Yoon E, Kim H

Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques Sensors. 2006;6(7):756–782 - PMCID: PMC3894536

Kim SJ, Zhao B, Im H, Min J, Choi N, Castro CM, Weissleder R, Lee H, Lee K

Deep-learning based hologram classification for molecular diagnostics bioRxiv. 2017;192559:ePub - DOI: 10.1101/192559

Naxerova K, Jain RK

Using tumour phylogenetics to identify the roots of metastasis in humans. Nat Rev Clin Oncol. 2015;12(5):258-72 - PMID: 25601447 - DOI: 10.1038/nrclinonc.2014.238

Rogers MS, Novak K, Zurakowski D, Cryan LM, Blois A, Lifshits E, Bø TH, Oyan AM, Bender ER, Lampa M, Kang SY, Naxerova K, Kalland KH, Straume O, Akslen LA, Watnick RS, Folkman J, Naumov GN

Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Mol Cancer Res. 2014;12(5):754-64 - PMID: 24574516 - PMCID: PMC4020951 - DOI: 10.1158/1541-7786.MCR-13-0532-T

Lin HY, Yang KS, Curley C, Lee H, Welch MW, Wolpin BM, Weissleder R, Im H, Castro C

Bead Enhancement of EV Analysis bioRxiv. 2018;:ePub - DOI: 10.1101/269423

Sieg E, Brook M, Linnoila J, VanHaerents S

Neuropsychological assessment as an objective tool to monitor treatment response in anti-N-methyl-D-aspartate receptor encephalitis. BMJ Case Rep. 2018;2018:ePub - PMID: 29884664 - PMCID: PMC6011453 - DOI: 10.1136/bcr-2018-224169

Linnoila J, Pulli B, Armangué T, Planagumà J, Narsimhan R, Schob S, Zeller MWG, Dalmau J, Chen J

Mouse model of anti-NMDA receptor post-herpes simplex encephalitis. Neurol Neuroimmunol Neuroinflamm. 2018;6(2):e529 - PMID: 30697582 - PMCID: PMC6340334 - DOI: 10.1212/NXI.0000000000000529

Vinegoni C, Feruglio PF, Weissleder R

High dynamic range fluorescence imaging. IEEE J Sel Top Quantum Electron. 2018;25(1):ePub - PMID: 31598059 - PMCID: PMC6785194 - DOI: 10.1109/JSTQE.2018.2881608

Vinegoni C, Feruglio PF, Weissleder R

High dynamic range fluorescence imaging. IEEE J Sel Top Quantum Electron. 2018;25(1):ePub - PMID: 31598059 - PMCID: PMC6785194 - DOI: 10.1109/JSTQE.2018.2881608

Liao HW, Garris C, Pfirschke C, Rickelt S, Arlauckas S, Siwicki M, Kohler RH, Weissleder R, Sundvold-Gjerstad V, Sveinbjørnsson B, Rekdal Ø, Pittet MJ

LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects. Cell Stress. 2019;3(11):348-360 - PMID: 31799501 - PMCID: PMC6859426 - DOI: 10.15698/cst2019.11.204

Hansen S, Wood DK, Higgins JM

5-(Hydroxymethyl)furfural restores low-oxygen rheology of sickle trait blood in vitro. Br J Haematol. 2019;188(6):985-993 - PMID: 31889311 - PMCID: PMC7150585 - DOI: 10.1111/bjh.16251

Raisbeck JC, Allen M, Weissleder R, Im H, Lee H

Evolution Strategies Converges to Finite Differences arXiv. 2020;:ePub

Foy BH, Carlson JCT, Reinertsen E, Padros Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM

Elevated RDW is Associated with Increased Mortality Risk in COVID-19 medRxiv. 2020;:ePub - DOI: 10.1101/2020.05.05.20091702

Liu Z, Ahn MH, Kurokawa T, Ly A, Zhang G, Wang F, Yamada T, Sadagopan A, Cheng J, Ferrone CR, Liss AS, Honselmann KC, Wojtkiewicz GR, Ferrone S, Wang X

A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma. J Transl Med. 2020;18(1):255 - PMID: 32580742 - PMCID: PMC7315507 - DOI: 10.1186/s12967-020-02414-9

Moradi Tuchayi S, Tam J, Wojtkiewicz GR, Kawa NI, Javorsky E, Anderson RR, Garibyan L

Injectable slurry for selective destruction of neck adipose tissue in New Zealand obese mouse model. Sleep Breath. 2020;24(4):1715-1718 - PMID: 32474829 - DOI: 10.1007/s11325-020-02111-3

Koch PD, Pittet MJ, Weissleder R

The chemical biology of IL-12 production via the non-canonical NFkB pathway RSC Chemical Biology. 2020;1:166-176 - PMID: 34458756 - PMCID: PMC8341911 - DOI: 10.1039/d0cb00022a

Bachar Issa TH, Vinegoni C, Shaw A, Fumene Feruglio P, Weissleder R, Uminsky D

Video-Rate Acquisition Fluorescence Microscopy via Generative Adversarial Networks EasyChair. 2020;:ePub

Naranbhai V, Chang CC, Beltran WFG, Miller TE, Astudillo MG, Villalba JA, Yang D, Gelfand J, Bernstein BE, Feldman J, Hauser BM, Caradonna TM, Alter G, Murali MR, Jasrasaria R, Quinlan J, Xerras DC, Betancourt JR, Louis DN, Schmidt AG, Lennerz J, Poznansky MC, Iafrate AJ

High seroprevalence of anti-SARS-CoV-2 antibodies in Chelsea, Massachusetts. J Infect Dis. 2020;222(12):1955-1959 - PMID: 32906151 - PMCID: PMC7499676 - DOI: 10.1093/infdis/jiaa579

Yue H, Nowak RP, Overwijn D, Payne NC, Fischinger S, Atyeo C, Baden LR, Nilles EJ, Karlson EW, Yu XG, Li JZ, Alter G, Mazitschek R, Fischer ES

Rapid 'mix and read' assay for scalable detection of SARS-CoV-2 antibodies in patient plasma. medRxiv. 2020;:ePub - PMID: 32909004 - PMCID: PMC7480056 - DOI: 10.1101/2020.09.01.20184101

Foy BH, Carlson JCT, Reinertsen E, Padros I Valls R, Pallares Lopez R, Palanques-Tost E, Mow C, Westover MB, Aguirre AD, Higgins JM

Association of Red Blood Cell Distribution Width With Mortality Risk in Hospitalized Adults With SARS-CoV-2 Infection. JAMA Netw Open. 2020;3(9):e2022058 - PMID: 32965501 - PMCID: PMC7512057 - DOI: 10.1001/jamanetworkopen.2020.22058

Goulet DR, Foster JP, Zawistowski JS, Bevill SM, Noël MP, Olivares-Quintero JF, Sciaky N, Singh D, Santos C, Pattenden SG, Davis IJ, Johnson GL

Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer. Mol Cancer Res. 2020;18(11):1685-1698 - PMID: 32753473 - PMCID: PMC7642176 - DOI: 10.1158/1541-7786.MCR-19-1011

Bevill SM, Olivares-Quintero JF, Sciaky N, Golitz BT, Singh D, Beltran AS, Rashid NU, Stuhlmiller TJ, Hale A, Moorman NJ, Santos CM, Angus SP, Zawistowski JS, Johnson GL

GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer. Mol Cancer Res. 2019;17(7):1503-1518 - PMID: 31000582 - PMCID: PMC6610760 - DOI: 10.1158/1541-7786.MCR-18-1121

Yao Q, Epstein CB, Banskota S, Issner R, Kim Y, Bernstein BE, Pinello L, Asgari MM

Epigenetic alterations in keratinocyte carcinoma. J Invest Dermatol. 2020;141(5):1207-1218 - PMID: 33212152 - PMCID: PMC8068579 - DOI: 10.1016/j.jid.2020.10.018

Kim H, Choia SK, Ahn J, Yu H, Kyoungha Min K, Hong C, Shin IS, Lee S, Lee H, Im H, Ko JG, Kim E

Kaleidoscopic fluorescent arrays for machine-learning-based point-of-care chemical sensing Sensors and Actuators B: Chemical. 2020;329:129248 - DOI: 10.1016/j.snb.2020.129248

Kim J, Lee SK, Schellingerhout D, Nahrendorf M, Kim K, Kim J, Kim DE

Spectroscopic Assessment of Gold Nanoparticle Biodistribution Using Surface Plasmon Resonance Phenomena. ACS Biomater Sci Eng. 2019;5(12):6389-6394 - PMID: 33417791 - DOI: 10.1021/acsbiomaterials.9b01079

Sandoval DR, Clausen TM, Nora C, Cribbs AP, Denardo A, Clark AE, Garretson AF, Coker JKC, Narayanan A, Majowicz SA, Philpott M, Johansson C, Dunford JE, Spliid CB, Golden GJ, Payne NC, Tye MA, Nowell CJ, Griffis ER, Piermatteo A, Grunddal KV, Alle T, Magida JA, Hauser BM, Feldman J, Caradonna TM, Pu Y, Yin X, McVicar RN, Kwong EM, Weiss RJ, Downes M, Tsimikas S, Smidt AG, Ballatore C, Zengler K, Evans RM, Chanda SK, Croker BA, Leibel SL, Jose J, Mazitschek R, Oppermann U, Esko JD, Carlin AF, Gordts PLSM

The Prolyl-tRNA Synthetase Inhibitor Halofuginone Inhibits SARS-CoV-2 Infection. bioRxiv. 2021;:ePub - PMID: 33791697 - PMCID: PMC8010724 - DOI: 10.1101/2021.03.22.436522

Pai SI

HPV-associated head and neck cancers. Otolaryngol Clin North Am. 2012;45(4):xi-xii - PMID: 22793861 - DOI: 10.1016/j.otc.2012.05.003

Banik G, Betts CB, Liudahl SM, Sivagnanam S, Kawashima R, Cotechini T, Larson W, Goecks J, Pai SI, Clayburgh DR, Tsujikawa T, Coussens LM

High-dimensional multiplexed immunohistochemical characterization of immune contexture in human cancers. Methods Enzymol. 2019;635:1-20 - PMID: 32122539 - PMCID: PMC7390987 - DOI: 10.1016/bs.mie.2019.05.039

Pai SI, Cesano A, Marincola FM

The Paradox of Cancer Immune Exclusion: Immune Oncology Next Frontier. Cancer Treat Res. 2020;180:173-195 - PMID: 32215870 - PMCID: PMC7423459 - DOI: 10.1007/978-3-030-38862-1_6

Pierce RH, Campbell JS, Pai SI, Brody JD, Kohrt HE

In-situ tumor vaccination: Bringing the fight to the tumor. Hum Vaccin Immunother. 2015;11(8):1901-9 - PMID: 26055074 - PMCID: PMC4635874 - DOI: 10.1080/21645515.2015.1049779

Pai SI, Tufano RP

Reoperation for recurrent/persistent well-differentiated thyroid cancer. Otolaryngol Clin North Am. 2010;43(2):353-63, ix - PMID: 20510718 - DOI: 10.1016/j.otc.2010.02.004

Wolkow N, Jakobiec FA, Afrogheh AH, Kidd M, Eagle RC, Pai SI, Faquin WC

PD-L1 and PD-L2 Expression Levels Are Low in Primary and Secondary Adenoid Cystic Carcinomas of the Orbit: Therapeutic Implications. Ophthalmic Plast Reconstr Surg. 2020;36(5):444-450 - PMID: 31990894 - PMCID: PMC7423458 - DOI: 10.1097/IOP.0000000000001585

Loyo M, Pai SI

The molecular genetics of laryngeal cancer. Otolaryngol Clin North Am. 2008;41(4):657-72, v - PMID: 18570952 - DOI: 10.1016/j.otc.2008.01.019

Pai SI, Cohen EEW, Lin D, Fountzilas G, Kim ES, Mehlhorn H, Baste N, Clayburgh D, Lipworth L, Resteghini C, Shara N, Fujii T, Zhang J, Stokes M, Wang H, Twumasi-Ankrah P, Wildsmith S, Khaliq A, Melillo G, Shire N

SUPREME-HN: a retrospective biomarker study assessing the prognostic value of PD-L1 expression in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck. J Transl Med. 2019;17(1):429 - PMID: 31878938 - PMCID: PMC6933901 - DOI: 10.1186/s12967-019-02182-1

Ishida E, Lee J, Campbell JS, Chakravarty PD, Katori Y, Ogawa T, Johnson L, Mukhopadhyay A, Faquin WC, Lin DT, Wirth LJ, Pierce RH, Pai SI

Intratumoral delivery of an HPV vaccine elicits a broad anti-tumor immune response that translates into a potent anti-tumor effect in a preclinical murine HPV model. Cancer Immunol Immunother. 2019;68(8):1273-1286 - PMID: 31243491 - PMCID: PMC6684362 - DOI: 10.1007/s00262-019-02357-1

Wolkow N, Jakobiec FA, Afrogheh AH, Pai SI, Faquin WC

High Expression of Programmed Death Ligand 1 and Programmed Death Ligand 2 in Ophthalmic Sebaceous Carcinoma: The Case for a Clinical Trial of Checkpoint Inhibitors. Am J Ophthalmol. 2020;220:128-139 - PMID: 32730911 - PMCID: PMC9361189 - DOI: 10.1016/j.ajo.2020.07.031

Wolkow N, Jakobiec FA, Afrogheh AH, Eagle RC, Pai SI, Faquin WC

Programmed Cell Death 1 Ligand 1 and Programmed Cell Death 1 Ligand 2 Are Expressed in Conjunctival Invasive Squamous Cell Carcinoma: Therapeutic Implications. Am J Ophthalmol. 2019;200:226-241 - PMID: 30633894 - PMCID: PMC7456462 - DOI: 10.1016/j.ajo.2018.12.020

Wu AA, Niparko KJ, Pai SI

Immunotherapy for head and neck cancer. J Biomed Sci. 2008;15(3):275-89 - PMID: 18392689 - DOI: 10.1007/s11373-008-9247-x

Rosenbaum MW, Gigliotti BJ, Pai SI, Parangi S, Wachtel H, Mino-Kenudson M, Gunda V, Faquin WC

PD-L1 and IDO1 Are Expressed in Poorly Differentiated Thyroid Carcinoma. Endocr Pathol. 2018;29(1):59-67 - PMID: 29372535 - PMCID: PMC6500591 - DOI: 10.1007/s12022-018-9514-y

Tufano RP, Pai SI

Thyroid and parathyroid surgery. Preface. Otolaryngol Clin North Am. 2010;43(2):xiii-xiv - PMID: 20510709 - DOI: 10.1016/j.otc.2010.04.001

Best SR, Niparko KJ, Pai SI

Biology of human papillomavirus infection and immune therapy for HPV-related head and neck cancers. Otolaryngol Clin North Am. 2012;45(4):807-22 - PMID: 22793854 - PMCID: PMC3398423 - DOI: 10.1016/j.otc.2012.04.005

Pai SI, Tufano RP

Central compartment neck dissection for thyroid cancer. Technical considerations. ORL J Otorhinolaryngol Relat Spec. 2008;70(5):292-7 - PMID: 18971593 - DOI: 10.1159/000149831

Gooi Z, Ward BK, Mener DJ, Ozgursoy OB, Pai SI

A staged thyroidectomy approach for gastric bypass patients. Laryngoscope. 2014;125(4):1028-30 - PMID: 25043176 - DOI: 10.1002/lary.24835

Kartha VK, Alamoud KA, Sadykov K, Nguyen BC, Laroche F, Feng H, Lee J, Pai SI, Varelas X, Egloff AM, Snyder-Cappione JE, Belkina AC, Bais MV, Monti S, Kukuruzinska MA

Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer. Genome Med. 2018;10(1):54 - PMID: 30029671 - PMCID: PMC6053793 - DOI: 10.1186/s13073-018-0569-7

Mohan S, Pai SI, Bhattacharyya N

Adjuvant radiotherapy is not supported in patients with verrucous carcinoma of the oral cavity. Laryngoscope. 2017;127(6):1334-1338 - PMID: 28150306 - PMCID: PMC7388729 - DOI: 10.1002/lary.26443

Bishop JA, Guo TW, Smith DF, Wang H, Ogawa T, Pai SI, Westra WH

Human papillomavirus-related carcinomas of the sinonasal tract. Am J Surg Pathol. 2013;37(2):185-92 - PMID: 23095507 - PMCID: PMC3545097 - DOI: 10.1097/PAS.0b013e3182698673

Ahn J, Bishop JA, Akpeng B, Pai SI, Best SR

Xenograft model for therapeutic drug testing in recurrent respiratory papillomatosis. Ann Otol Rhinol Laryngol. 2014;124(2):110-5 - PMID: 25124839 - PMCID: PMC7423457 - DOI: 10.1177/0003489414546400

Gleber-Netto FO, Zhao M, Trivedi S, Wang J, Jasser S, McDowell C, Kadara H, Zhang J, Wang J, William WN, Lee JJ, Nguyen ML, Pai SI, Walline HM, Shin DM, Ferris RL, Carey TE, Myers JN, Pickering CR, Head and Neck Cancer Specialized Program of Research Excellence (SPORE) Human Immunodeficiency Virus (HIV) Supplement Consortium

Distinct pattern of TP53 mutations in human immunodeficiency virus-related head and neck squamous cell carcinoma. Cancer. 2017;124(1):84-94 - PMID: 29053175 - PMCID: PMC5785080 - DOI: 10.1002/cncr.31063

Zhang H, Kim S, Chen Z, Nannapaneni S, Chen AY, Moore CE, Sica G, Mosunjac M, Nguyen MLT, D'Souza G, Carey TE, Peterson LA, McHugh JB, Graham M, Komarck CM, Wolf GT, Walline HM, Bellile E, Riddell J, Pai SI, Sidransky D, Westra WH, William WN, Lee JJ, El-Naggar AK, Ferris RL, Seethala R, Grandis JR, Chen ZG, Saba NF, Shin DM, Head and Neck Cancer SPORE HIV supplement consortium

Prognostic biomarkers in patients with human immunodeficiency virus-positive disease with head and neck squamous cell carcinoma. Head Neck. 2017;39(12):2433-2443 - PMID: 28945296 - PMCID: PMC5808949 - DOI: 10.1002/hed.24911

Pai SI

Adaptive immune resistance in HPV-associated head and neck squamous cell carcinoma. OncoImmunology. 2013;2(5):e24065 - PMID: 23762795 - PMCID: PMC3667901 - DOI: 10.4161/onci.24065

Dʼsouza G, Carey TE, William WN, Nguyen ML, Ko EC, Riddell J, Pai SI, Gupta V, Walline HM, Lee JJ, Wolf GT, Shin DM, Grandis JR, Ferris RL

Epidemiology of head and neck squamous cell cancer among HIV-infected patients. J Acquir Immune Defic Syndr. 2014;65(5):603-10 - PMID: 24326607 - PMCID: PMC3999230 - DOI: 10.1097/QAI.0000000000000083

Pai SI, Wirth LJ

Checkpoint cluster: biomarkers of response. Emerg Top Life Sci. 2017;1(5):501-508 - PMID: 33525795 - DOI: 10.1042/ETLS20170077

Peng S, Mattox A, Best SR, Barbu AM, Burns JA, Akpeng B, Jeang J, Yang B, Ishida E, Hung CF, Wu TC, Pai SI

Identification of the murine H-2D(b) and human HLA-A*0201 MHC class I-restricted HPV6 E7-specific cytotoxic T lymphocyte epitopes. Cancer Immunol Immunother. 2016;65(3):261-71 - PMID: 26759151 - PMCID: PMC5690558 - DOI: 10.1007/s00262-016-1793-x

Walline HM, Carey TE, Goudsmit CM, Bellile EL, D'Souza G, Peterson LA, McHugh JB, Pai SI, Lee JJ, Shin DM, Ferris RL, HNC SPORE HIV supplement consortium

High-Risk HPV, Biomarkers, and Outcome in Matched Cohorts of Head and Neck Cancer Patients Positive and Negative for HIV. Mol Cancer Res. 2016;15(2):179-188 - PMID: 27899422 - PMCID: PMC5290187 - DOI: 10.1158/1541-7786.MCR-16-0255

Lin BM, Wang H, D'Souza G, Zhang Z, Fakhry C, Joseph AW, Drake VE, Sanguineti G, Westra WH, Pai SI

Long-term prognosis and risk factors among patients with HPV-associated oropharyngeal squamous cell carcinoma. Cancer. 2013;119(19):3462-71 - PMID: 23861037 - PMCID: PMC3788050 - DOI: 10.1002/cncr.28250

Lyford-Pike S, Westra WH, Loyo M, Peng S, Hung CF, Wu AA, Flint PW, Tunkel DE, Saunders JR, Pai SI

Differential expression of epidermal growth factor receptor in juvenile and adult-onset recurrent respiratory papillomatosis. Histopathology. 2010;57(5):768-70 - PMID: 21083608 - DOI: 10.1111/j.1365-2559.2010.03691.x

Wu G, Pai SI, Agrawal N, Richmon J, Dackiw A, Tufano RP

Profile of patients with completion thyroidectomy and assessment of their suitability for outpatient surgery. Otolaryngol Head Neck Surg. 2011;145(5):727-31 - PMID: 21860058 - DOI: 10.1177/0194599811416749

Cho YG, Chang X, Park IS, Yamashita K, Shao C, Ha PK, Pai SI, Sidransky D, Kim MS

Promoter methylation of leukemia inhibitory factor receptor gene in colorectal carcinoma. Int J Oncol. 2011;39(2):337-44 - PMID: 21617854 - PMCID: PMC3601031 - DOI: 10.3892/ijo.2011.1050

Anderson KS, Wong J, D'Souza G, Riemer AB, Lorch J, Haddad R, Pai SI, Longtine J, McClean M, LaBaer J, Kelsey KT, Posner M

Serum antibodies to the HPV16 proteome as biomarkers for head and neck cancer. Br J Cancer. 2011;104(12):1896-905 - PMID: 21654689 - PMCID: PMC3111202 - DOI: 10.1038/bjc.2011.171

Tsen SW, Wu CY, Meneshian A, Pai SI, Hung CF, Wu TC

Femtosecond laser treatment enhances DNA transfection efficiency in vivo. J Biomed Sci. 2009;16:36 - PMID: 19338665 - PMCID: PMC2669473 - DOI: 10.1186/1423-0127-16-36

Loyo M, Pai SI, Netto GJ, Tunkel DE

Aggressive recurrent respiratory papillomatosis in a neonate. Int J Pediatr Otorhinolaryngol. 2008;72(6):917-20 - PMID: 18423627 - DOI: 10.1016/j.ijporl.2008.02.022

Peng S, Best SR, Hung CF, Loyo M, Lyford-Pike S, Flint PW, Tunkel DE, Saunders JR, Wu TC, Pai SI

Characterization of human papillomavirus type 11-specific immune responses in a preclinical model. Laryngoscope. 2010;120(3):504-10 - PMID: 20025042 - PMCID: PMC2908018 - DOI: 10.1002/lary.20745

Sedaghat AR, Zhang Z, Begum S, Palermo R, Best S, Ulmer KM, Levine M, Zinreich E, Messing BP, Gold D, Wu AA, Niparko KJ, Kowalski J, Hirata RM, Saunders JR, Westra WH, Pai SI

Prognostic significance of human papillomavirus in oropharyngeal squamous cell carcinomas. Laryngoscope. 2009;119(8):1542-9 - PMID: 19522004 - DOI: 10.1002/lary.20533

Peng S, Lyford-Pike S, Akpeng B, Wu A, Hung CF, Hannaman D, Saunders JR, Wu TC, Pai SI

Low-dose cyclophosphamide administered as daily or single dose enhances the antitumor effects of a therapeutic HPV vaccine. Cancer Immunol Immunother. 2012;62(1):171-82 - PMID: 23011589 - PMCID: PMC3543472 - DOI: 10.1007/s00262-012-1322-5

Kim D, Hoory T, Monie A, Wu A, Hsueh WT, Pai SI, Hung CF

Delivery of chemotherapeutic agents using drug-loaded irradiated tumor cells to treat murine ovarian tumors. J Biomed Sci. 2010;17:61 - PMID: 20659328 - PMCID: PMC2918546 - DOI: 10.1186/1423-0127-17-61

Jara SM, Carson KA, Pai SI, Agrawal N, Richmon JD, Prescott JD, Dackiw A, Zeiger MA, Bishop JA, Tufano RP

The relationship between chronic lymphocytic thyroiditis and central neck lymph node metastasis in North American patients with papillary thyroid carcinoma. Surgery. 2013;154(6):1272-80; discussion 1280-2 - PMID: 24238047 - DOI: 10.1016/j.surg.2013.07.021

Bishop JA, Ogawa T, Stelow EB, Moskaluk CA, Koch WM, Pai SI, Westra WH

Human papillomavirus-related carcinoma with adenoid cystic-like features: a peculiar variant of head and neck cancer restricted to the sinonasal tract. Am J Surg Pathol. 2013;37(6):836-44 - PMID: 23598962 - PMCID: PMC3653997 - DOI: 10.1097/PAS.0b013e31827b1cd6

Park IS, Chang X, Loyo M, Wu G, Chuang A, Kim MS, Chae YK, Lyford-Pike S, Westra WH, Saunders JR, Sidransky D, Pai SI

Characterization of the methylation patterns in human papillomavirus type 16 viral DNA in head and neck cancers. Cancer Prev Res (Phila). 2011;4(2):207-17 - PMID: 21292634 - PMCID: PMC3079312 - DOI: 10.1158/1940-6207.CAPR-10-0147

Flint PW, Li ZB, Lehar M, Saito K, Pai SI

Laryngeal muscle surface receptors identified using random phage library. Laryngoscope. 2005;115(11):1930-7 - PMID: 16319601 - DOI: 10.1097/01.mlg.0000172273.98418.8d

Bishop JA, Ogawa T, Chang X, Illei PB, Gabrielson E, Pai SI, Westra WH

HPV analysis in distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma. Am J Surg Pathol. 2012;36(1):142-8 - PMID: 22173119 - PMCID: PMC3273906 - DOI: 10.1097/PAS.0b013e3182395c7b

Best SR, Ha PK, Blanco RG, Saunders JR, Zinreich ES, Levine MA, Pai SI, Walker M, Trachta J, Ulmer K, Murakami P, Thompson R, Califano JA, Messing BP

Factors associated with pharyngoesophageal stricture in patients treated with concurrent chemotherapy and radiation therapy for oropharyngeal squamous cell carcinoma. Head Neck. 2011;33(12):1727-34 - PMID: 21246640 - PMCID: PMC4695991 - DOI: 10.1002/hed.21657

Wu G, Fraser S, Pai SI, Farrag TY, Ladenson PW, Tufano RP

Determining the extent of lateral neck dissection necessary to establish regional disease control and avoid reoperation after previous total thyroidectomy and radioactive iodine for papillary thyroid cancer. Head Neck. 2011;34(10):1418-21 - PMID: 22052539 - DOI: 10.1002/hed.21937

Hillel AT, Fakhry C, Pai SI, Williams MF, Blanco RG, Zinreich ES, Levine MA, Westra WH, Saunders JR, Ha PK

Selective versus comprehensive neck dissection after chemoradiation for advanced oropharyngeal squamous cell carcinoma. Otolaryngol Head Neck Surg. 2009;141(6):737-42 - PMID: 19932847 - DOI: 10.1016/j.otohns.2009.09.010

Goldenberg D, Begum S, Westra WH, Khan Z, Sciubba J, Pai SI, Califano JA, Tufano RP, Koch WM

Cystic lymph node metastasis in patients with head and neck cancer: An HPV-associated phenomenon. Head Neck. 2008;30(7):898-903 - PMID: 18383529 - DOI: 10.1002/hed.20796

Kim TW, Hung CF, Zheng M, Boyd DA, He L, Pai SI, Wu TC

A DNA vaccine co-expressing antigen and an anti-apoptotic molecule further enhances the antigen-specific CD8+ T-cell immune response. J Biomed Sci. 2004;11(4):493-9 - PMID: 15153784 - DOI: 10.1007/BF02256098

Dong SM, Pai SI, Rha SH, Hildesheim A, Kurman RJ, Schwartz PE, Mortel R, McGowan L, Greenberg MD, Barnes WA, Sidransky D

Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma. Cancer Epidemiol Biomarkers Prev. 2002;11(1):3-6 - PMID: 11815394

Cheng WF, Hung CF, Pai SI, Hsu KF, He L, Ling M, Wu TC

Repeated DNA vaccinations elicited qualitatively different cytotoxic T lymphocytes and improved protective antitumor effects. J Biomed Sci. 2002;9(6 Pt 2):675-87 - PMID: 12432234 - DOI: 10.1159/000067285

Pai SI, Limb CJ, Nicol T, Williams MF

Leiomyosarcoma of the auricle. Otolaryngol Head Neck Surg. 2003;128(3):442-4 - PMID: 12646855 - DOI: 10.1067/mhn.2003.16

Lin LM, Pai SI, Flint PW

A retropharyngeal pseudoabscess in a patient with paroxysmal nocturnal hemoglobinuria. Otolaryngol Head Neck Surg. 2007;137(4):684-6 - PMID: 17903595 - DOI: 10.1016/j.otohns.2007.01.032

Nichols RC, Blinder J, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P

Assignment of two human autoantigen genes-isoleucyl-tRNA synthetase locates to 9q21 and lysyl-tRNA synthetase locates to 16q23-q24. Genomics. 1996;36(1):210-3 - PMID: 8812440 - DOI: 10.1006/geno.1996.0449

Nichols RC, Pai SI, Ge Q, Targoff IN, Plotz PH, Liu P

Localization of two human autoantigen genes by PCR screening and in situ hybridization--glycyl-tRNA synthetase locates to 7p15 and alanyl-tRNA synthetase locates to 16q22. Genomics. 1995;30(1):131-2 - PMID: 8595897 - DOI: 10.1006/geno.1995.0028

Pai SI, Goldstein BJ, Studeman KD, Westra WH, Tufano RP

Concurrent sporadic parathyroid adenoma and carcinoma. Am J Otolaryngol. 2006;27(5):346-8 - PMID: 16935182 - DOI: 10.1016/j.amjoto.2005.11.017

Friedmann AS, Malott KA, Memoli VA, Pai SI, Yu XM, North WG

Products of vasopressin gene expression in small-cell carcinoma of the lung. Br J Cancer. 1994;69(2):260-3 - PMID: 8297723 - PMCID: PMC1968694 - DOI: 10.1038/bjc.1994.49

Deyell M, Garris CS, Laughney AM

Cancer metastasis as a non-healing wound. Br J Cancer. 2021;124(9):1491-1502 - PMID: 33731858 - PMCID: PMC8076293 - DOI: 10.1038/s41416-021-01309-w

Garris CS, Blaho VA, Hla T, Han MH

Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond. Immunology. 2014;142(3):347-53 - PMID: 24597601 - PMCID: PMC4080950 - DOI: 10.1111/imm.12272

Hackney JA, Misaghi S, Senger K, Garris C, Sun Y, Lorenzo MN, Zarrin AA

DNA targets of AID evolutionary link between antibody somatic hypermutation and class switch recombination. Adv Immunol. 2009;101:163-89 - PMID: 19231595 - DOI: 10.1016/S0065-2776(08)01005-5

Bill R, Deschler DG, Pittet MJ, Pai SI, Sadow PM, Park JC

Diagnostic challenges and successful organ-preserving therapy in a case of secretory carcinoma of minor salivary glands. Cancer Rep (Hoboken). 2021;5(3):e1491 - PMID: 34231337 - PMCID: PMC8955062 - DOI: 10.1002/cnr2.1491

Foy BH, Sundt T, Carlson JCT, Aguirre AD, Higgins JM

White Blood Cell and Platelet Dynamics Define Human Inflammatory Recovery. medRxiv. 2021;:ePub - PMID: 34189534 - PMCID: PMC8240689 - DOI: 10.1101/2021.06.19.21259181

Spitzberg J, Ferguson S, Yang K, Peterson HM, Carlson JCT, Weissleder R

Multiplexed analysis of a single EV (MASEV) reveals unique biomarker composition with diagnostic impact bioRxiv. 2022;:ePub - DOI: 10.1101/2022.06.17.496607

Guo JA, Alshalalfa M, Kim DY, Hoffman HI, Shiau C, Su J, Hwang WL, Mahal BA

DNA repair and immune checkpoint blockade response. Cancer Genet. 2022;264-265:1-4 - PMID: 35245846 - DOI: 10.1016/j.cancergen.2022.02.007

Swami N, Hwang WL, Guo JA, Hoffman H, Abramowitz MC, Elbakouny Z, Beltran H, Chipidza F, Choueiri T, Pra AD, Huang F, Kaochar S, Kantoff P, Kim DW, Kishan AU, Kobetz E, Marinac C, Mucci LA, Muralidhar V, Pollack A, Sanford NN, Schaeffer EM, Spratt DE, Zhao SG, Rebbeck TR, Nguyen PL, Feng FY, Mahal BA, Alshalalfa M

Novel genomic signature predictive of response to immune checkpoint blockade: A pan-cancer analysis from project Genomics Evidence Neo-plasia Information Exchange (GENIE). Cancer Genet. 2021;258-259:61-68 - PMID: 34551377 - DOI: 10.1016/j.cancergen.2021.08.004

Mehta A, Hwang WL, Weekes C

The present and future of systemic and microenvironment-targeted therapy for pancreatic adenocarcinoma. Ann Pancreat Cancer. 2020;3:ePub - PMID: 33294843 - PMCID: PMC7720884 - DOI: 10.21037/apc-2020-pda-05

Grossberg AJ, Chu LC, Deig CR, Fishman EK, Hwang WL, Maitra A, Marks DL, Mehta A, Nabavizadeh N, Simeone DM, Weekes CD, Thomas CR

Multidisciplinary standards of care and recent progress in pancreatic ductal adenocarcinoma. CA Cancer J Clin. 2020;70(5):375-403 - PMID: 32683683 - PMCID: PMC7722002 - DOI: 10.3322/caac.21626

Hoffman HI, Guo JA, Hawkins MA, Bridgewater JA, Wo JY, Hong TS, Hwang WL

Silver Linings: An Opportunity to Improve Clinical Paradigms After the COVID-19 Pandemic. JCO Oncol Pract. 2020;16(9):532-534 - PMID: 32469687 - DOI: 10.1200/OP.20.00335

Kim DW, Buzurovic IM, Mahal BV, Hwang W, Oladeru OT, O'Farrell DA, Harris TC, Margalit DN, Lam M, Devlin PM

Combined interstitial and surface high-dose-rate brachytherapy treatment of squamous cell carcinoma of the hand. J Contemp Brachytherapy. 2020;12(1):48-52 - PMID: 32190070 - PMCID: PMC7073341 - DOI: 10.5114/jcb.2020.92408

Pike LRG, Royce TJ, Mahal AR, Kim DW, Hwang WL, Mahal BA, Sanford NN

Outcomes of HPV-Associated Squamous Cell Carcinoma of the Head and Neck: Impact of Race and Socioeconomic Status. J Natl Compr Canc Netw. 2020;18(2):177-184 - PMID: 32023531 - PMCID: PMC7384230 - DOI: 10.6004/jnccn.2019.7356

Lamba N, Hwang WL, Kim DW, Niemierko A, Marciscano AE, Mehan WA, Benayoun MD, Curry WT, Barker FG, Martuza RL, Dunn IF, Claus E, Bi WL, Aizer AA, Alexander BM, Oh KS, Loeffler JS, Shih HA

Atypical Histopathological Features and the Risk of Treatment Failure in Nonmalignant Meningiomas: A Multi-Institutional Analysis. World Neurosurg. 2019;133:e804-e812 - PMID: 31605839 - DOI: 10.1016/j.wneu.2019.10.002

Liu KX, Lamba N, Hwang WL, Niemierko A, DuBois SG, Haas-Kogan DA

Risk stratification by somatic mutation burden in Ewing sarcoma. Cancer. 2019;125(8):1357-1364 - PMID: 30602061 - DOI: 10.1002/cncr.31919

Hwang WL, Pike LRG, Royce TJ, Mahal BA, Loeffler JS

Safety of combining radiotherapy with immune-checkpoint inhibition. Nat Rev Clin Oncol. 2018;15(8):477-494 - PMID: 29872177 - DOI: 10.1038/s41571-018-0046-7

Hwang KL, Hwang WL, Bussière MR, Shih HA

The role of radiotherapy in the management of high-grade meningiomas. Chin Clin Oncol. 2017;6(Suppl 1):S5 - PMID: 28758409 - DOI: 10.21037/cco.2017.06.09

Hwang WL, Hwang KL, Miyamoto DT

The promise of circulating tumor cells for precision cancer therapy. Biomark Med. 2016;10(12):1269-1285 - PMID: 27924634 - PMCID: PMC5827810 - DOI: 10.2217/bmm-2016-0192

Hwang WL, Jagadeesh KA, Guo JA, Hoffman HI, Yadollahpour P, Mohan R, Drokhlyansky E, Van Wittenberghe N, Ashenberg O, Farhi S, Schapiro D, Reeves J, Zollinger DR, Eng G, Schenkel JM, Freed-Pastor WA, Rodrigues C, Gould J, Lambden C, Porter C, Tsankov A, Dionne D, Abbondanza D, Waldman J, Cuoco M, Nguyen L, Delorey T, Phillips D, Ciprani D, Kern M, Mehta A, Fuhrman K, Fropf R, Beechem J, Loeffler JS, Ryan DP, Weekes CD, Ting DT, Ferrone CR, Wo JY, Hong TS, Aguirre AJ, Rozenblatt-Rosen O, Mino-Kenudson M, Fernandez-del Castillo C, Liss AS, Jacks TE, Regev A

Single-nucleus and spatial transcriptomics of archival pancreatic cancer reveals multi-compartment reprogramming after neoadjuvant treatment bioRxiv. 2020;:ePub - DOI: 10.1101/2020.08.25.267336

Szu H, Hwang WL

Self-supervised backpropagation in stem cells IEEE Connections. 2003;1(3):8-9

Su F, Hwang WL, Mukherjee A, Chakrabarty K

Testing and diagnosis of realistic defects in digital microfluidic biochips Journal of Electronic Testing. 2007;23(2-3):219-33

Xu T, Hwang WL, Su F, Chakrabarty K.

Automated design of pin-constrained digital microfluidic biochips under droplet-interference constraints Journal on Emerging Technologies in Computing. 2007;3(3):14

Jo A, Green A, Medina JE, Iyer S, Ohman AW, McCarthy ET, Reinhardt F, Gerton T, Demehin D, Mishra R, Kolin DL, Zheng H, Crum CP, Weinberg RA, Rueda BR, Castro CM, Dinulescu DM, Lee H

Profiling extracellular vesicles in circulation enables the early detection of ovarian cancer. bioRxiv. 2023;:ePub - PMID: 36711872 - PMCID: PMC9882285 - DOI: 10.1101/2023.01.19.524549

Lutz EA, Jailkhani N, Momin N, Huang Y, Sheen A, Kang BH, Wittrup KD, Hynes RO

Intratumoral nanobody-IL-2 fusions that bind the tumor extracellular matrix suppress solid tumor growth in mice. PNAS Nexus. 2022;1(5):pgac244 - PMID: 36712341 - PMCID: PMC9802395 - DOI: 10.1093/pnasnexus/pgac244

Yin Z, Wu L, Zhang Y, Sun Y, Chen JW, Subudhi S, Ho W, Lee GY, Wang A, Gao X, Ren J, Zhu C, Zhang N, Ferraro GB, Muzikansky A, Zhang L, Stemmer-Rachamimov A, Mao J, Plotkin SR, Xu L

Co-Targeting IL-6 and EGFR signaling for the treatment of schwannomatosis and associated pain. bioRxiv. 2023;:ePub - PMID: 36798353 - PMCID: PMC9934519 - DOI: 10.1101/2023.02.06.527377

Shiau C, Cao J, Gregory MT, Gong D, Yin X, Cho JW, Wang PL, Su J, Wang S, Reeves JW, Kim TK, Kim Y, Guo JA, Lester NA, Schurman N, Barth JL, Weissleder R, Jacks T, Qadan M, Hong TS, Wo JY, Roberts H, Beechem JM, Fernandez-Del Castillo C, Mino-Kenudson M, Ting DT, Hemberg M, Hwang WL

Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis. bioRxiv. 2023;:ePub - PMID: 37425692 - PMCID: PMC10327107 - DOI: 10.1101/2023.06.28.546848

Stollmann A, Garcia-Guirado J, Hong JS, Im H, Lee H, Arroyo JO, Quidant R

Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform. arXiv. 2023;:ePub - PMID: 37608933 - PMCID: PMC10441434

Zhang LH, Tozzo V, Higgins JM, Ranganath R

Set Norm and Equivariant Skip Connections: Putting the Deep in Deep Sets. Proc Mach Learn Res. 2022;162:26559-26574 - PMID: 37645424 - PMCID: PMC10465016

Gustafsson K, Rhee C, Frodermann V, Scadden EW, Li D, Iwamoto Y, Palchaudhuri R, Hyzy SL, Boitano AE, Nahrendorf M, Scadden DT

CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer. bioRxiv. 2023;:ePub - PMID: 37732224 - PMCID: PMC10508759 - DOI: 10.1101/2023.09.05.556397

Foy BH, Petherbridge R, Roth M, Mow C, Patel HR, Patel CH, Ho SN, Lam E, Karczewski KJ, Tozzo V, Higgins JM

Hematologic setpoints are a stable and patient-specific deep phenotype. medRxiv. 2023;:ePub - PMID: 37808854 - PMCID: PMC10557837 - DOI: 10.1101/2023.09.26.23296146

Arroyo JO, Stollmann A, Garcia-Guirado J, Hong JS, Im H, Lee H, Quidant R

Molecular fingerprinting of biological nanoparticles with a label-free optofluidic platform. Res Sq. 2023;:ePub - PMID: 37886549 - PMCID: PMC10602063 - DOI: 10.21203/rs.3.rs-3309306/v1

Landeros C, Oh J, Weissleder R, Lee H

Deep Learning Pipeline for Automated Cell Profiling from Cyclic Imaging. Res Sq. 2023;:ePub - PMID: 38196620 - PMCID: PMC10775369 - DOI: 10.21203/rs.3.rs-3745061/v1

Alam R, Aguirre AD, Stultz CM

QTNet: Deep Learning for Estimating QT Intervals Using a Single Lead ECG. Annu Int Conf IEEE Eng Med Biol Soc. 2023;2023:1-4 - PMID: 38261472 - DOI: 10.1109/EMBC40787.2023.10341204

Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N

Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes. bioRxiv. 2024;:ePub - PMID: 38798619 - PMCID: PMC11118476 - DOI: 10.1101/2024.05.14.593897

Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB

KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes. bioRxiv. 2024;:ePub - PMID: 38798357 - PMCID: PMC11118371 - DOI: 10.1101/2024.05.14.593970

Payne NC, Ichikawa S, Woo CM, Mazitschek R

Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology. STAR Protoc. 2024;5(2):103129 - PMID: 38857155 - PMCID: PMC11193044 - DOI: 10.1016/j.xpro.2024.103129

Petrozziello T, Motlagh NJ, Monsanto RZB, Lei D, Murcar MG, Penney EB, Bragg DC, Fernandez-Cerado C, Legarda GP, Sy M, Muñoz E, Ang MC, Diesta CCE, Zhang C, Tanzi RE, Qureshi IA, Chen JW, Sadri-Vakili G

Targeting myeloperoxidase to reduce neuroinflammation in X-linked dystonia parkinsonism. medRxiv. 2024;:ePub - PMID: 38978657 - PMCID: PMC11230314 - DOI: 10.1101/2024.06.25.24309481

Momin N, Pabel S, Rudra A, Kumowski N, Lee IH, Mentkowski K, Yamazoe M, Stengel L, Muse CG, Seung H, Paccalet A, Gonzalez-Correa C, Jacobs EB, Grune J, Schloss MJ, Sossalla S, Wojtkiewicz G, Iwamoto Y, McMullen P, Mitchell RN, Ellinor PT, Anderson DG, Naxerova K, Nahrendorf M, Hulsmans M

Therapeutic Spp1 silencing in TREM2 + cardiac macrophages suppresses atrial fibrillation. bioRxiv. 2024;:ePub - PMID: 39149373 - PMCID: PMC11326243 - DOI: 10.1101/2024.08.10.607461

Quintana JM, Jiang F, Kang M, Valladolid Onecha V, Könik A, Qin L, Rodriguez VE, Hu H, Borges N, Khurana I, Banla LI, Le Fur M, Caravan P, Schuemann J, Bertolet A, Weissleder R, Miller MA, Ng TSC

Localized in vivo prodrug activation using radionuclides. bioRxiv. 2024;:ePub - PMID: 39211146 - PMCID: PMC11361159 - DOI: 10.1101/2024.08.02.606075

Uygun K, von Reiterdank IF, Mojoudi M, Bento R, Taggart M, Dinicu A, Wojtkiewicz G, Coert J, van der Molen AM, Weissleder R, Parekkadan B

Ex Vivo Machine Perfusion as a Platform for Lentiviral Gene Delivery in Rat Livers. Res Sq. 2024;:ePub - PMID: 39315250 - PMCID: PMC11419271 - DOI: 10.21203/rs.3.rs-4784505/v1

Wassenaar EC, Gorelick AN, Hung WT, Cheek DM, Kucukkose E, Lee IH, Blohmer M, Degner S, Giunta P, Wiezer RM, Raicu MG, Ubink I, Klaasen SJ, Lansu N, Watson EV, Corcoran RB, Boland G, Getz G, Kops GJ, Juric D, Lennerz JK, Boerma D, Kranenburg O, Naxerova K

A unique interplay of access and selection shapes peritoneal metastasis evolution in colorectal cancer. bioRxiv. 2024;:ePub - PMID: 39386634 - PMCID: PMC11463674 - DOI: 10.1101/2024.09.25.614736

Di Ianni E, Jeon J, Hu H, Quintana JM, Lee C, Haidar EA, Mohammadi S, Zargani-Piccardi A, Mahamdeh M, Hernández IC, Ng TSC, Breyne K, Lee H, Breakefield XO, Miller MA

Enhanced mRNA delivery using ultrasound-delivered click reactive anchors. bioRxiv. 2025;:ePub - PMID: 39975219 - PMCID: PMC11838329 - DOI: 10.1101/2025.01.28.635330

Tozzo V, Petherbridge R, James K, Hsu S, Michalopoulos C, Foy BH, Thaweethai T, Mow C, Maya J, Camero CB, Shook L, Gray KJ, Mauney L, Higgins JM, Powe CE

Hematologic dynamics during pregnancy and their association with obstetric complications: a retrospective cohort study. medRxiv. 2025;:ePub - PMID: 39990572 - PMCID: PMC11844592 - DOI: 10.1101/2025.02.13.25322250

Gong D, Liu R, Cui Y, Rhodes M, Bae JW, Beechem JM, Hwang WL

Integrated spatial morpho-transcriptomics predicts functional traits in pancreatic cancer. bioRxiv. 2025;:ePub - PMID: 40161804 - PMCID: PMC11952565 - DOI: 10.1101/2025.03.12.642933

Szafraniec HM, Bull F, Higgins JM, Stone HA, Krüger T, Pearce P, Wood DK

Suspension physics govern the multiscale dynamics of blood flow in sickle cell disease. bioRxiv. 2025;:ePub - PMID: 40161781 - PMCID: PMC11952557 - DOI: 10.1101/2025.03.13.642599

Lloyd HC, Li Y, Payne N, Zhao Z, Xu W, Kroupova A, Zollman D, Long T, Kabir F, Chen M, Freeman R, Feng EY, Xi S, Hsu YC, Ciulli A, Mazitschek R, Woo CM

A method for the detection and enrichment of endogenous cereblon substrates. bioRxiv. 2025;:ePub - PMID: 40196695 - PMCID: PMC11974815 - DOI: 10.1101/2025.03.24.645063

Tozzo V, Zhang LH, Ranganath R, Higgins JM

Transformer-based artificial intelligence on single-cell clinical data for homeostatic mechanism inference and rational biomarker discovery. medRxiv. 2025;:ePub - PMID: 40196278 - PMCID: PMC11974774 - DOI: 10.1101/2025.03.24.25324556

Palanques-Tost E, Pallarès-López R, Padrós-Valls R, Song S, Reinertsen E, Churchill TW, Stockwell P, Pomerantsev E, Garasic J, Sundt TM, Shah P, Houstis NE, Aguirre AD

Cardiac Output Estimation in the Intensive Care Unit. JACC Adv. 2025;4(5):101663 - PMID: 40286350 - PMCID: PMC12101535 - DOI: 10.1016/j.jacadv.2025.101663

Merz ML, Shoba VM, Pergu R, Severance ZC, Munkanatta Godage DNP, Deb A, Kwok HS, Singh P, Singh S, Allen JB, Tian W, Gosavi PM, Chaudhary SK, Anokhina V, Weisberg EL, Payne NC, He Y, Osadchey R, Shekhar M, Mazitschek R, Rees MG, Roth JA, Cui Q, Griffin JD, Liau BB, Choudhary A

Phosphorylation-inducing chimera rewires oncogenic kinase to trigger apoptosis. bioRxiv. 2025;:ePub - PMID: 40661463 - PMCID: PMC12259158 - DOI: 10.1101/2025.06.13.659082

Williams DC, Higgins JM, Wood DK

Quantifying the unique mechanical properties of irreversibly sickled cells in sickle cell disease. Blood Vessel Thromb Hemost. 2025;2(3):100077 - PMID: 40765910 - PMCID: PMC12320412 - DOI: 10.1016/j.bvth.2025.100077

Li J, Aguirre AD, Moura V, Jin J, Liu C, Zhong L, Sun C, Clifford G, Westover MB, Hong S

An Electrocardiogram Foundation Model Built on over 10 Million Recordings. NEJM AI. 2025;2(7):ePub - PMID: 40771651 - PMCID: PMC12327759 - DOI: 10.1056/aioa2401033

Arbesfeld-Qiu JM, Cho JW, Nguyen PTT, Lester NA, Su J, Guo JA, Hoffman H, Shiau C, Caldwell N, Muratani S, Galvan M, Proctor JE, Ely Z, Wang S, Ganci M, Dries R, Hong T, Wo J, Boland G, Fernandez-Del Castillo C, Ferrone C, Heaphy CM, Zhang ML, Mino-Kenudson M, Hemberg M, Hwang WL

Distinct malignant cell states and myeloid glutamate signaling associated with aggressive pancreatic neuroendocrine tumors. bioRxiv. 2025;:ePub - PMID: 40791359 - PMCID: PMC12338628 - DOI: 10.1101/2025.07.15.664730

Wang P, Lester N, Perrault E, Su J, Gong D, Shiau C, Cao J, Nguyen P, Bae JW, Olgun D, Hoffman H, Lam A, Huang-Gao J, Rahaman S, Guo J, Barth J, Caldwell N, Divakar P, Reeves J, Bahrami A, He S, Patrick M, Miller E, Ganci M, Cervantes-Jaramillo G, Hong T, Wo J, Roberts H, Weissleder R, Choi H, Fernandez-Del-Castillo C, Cormier K, Ting DT, Jacks T, Zheng L, Hemberg M, Mino-Kenudson M, Hwang WL

The Pdgfd-Pdgfrb axis orchestrates tumor-nerve crosstalk in pancreatic cancer. bioRxiv. 2025;:ePub - PMID: 40909696 - PMCID: PMC12407889 - DOI: 10.1101/2025.08.26.672505

Hron BM, Ng TSC, Najafi Khosroshahi F, Kourmouzi V, Drubach LA, Voss S, Rosen RL, Packard A

In vitro radionuclide labeling characteristics of blenderized tube feeds for quantitative gastric motility assessment. JPGN Rep. 2025;6(4):377-381 - PMID: 41245026 - PMCID: PMC12611584 - DOI: 10.1002/jpr3.70066

Cheek D, Blohmer M, Nowak M, Antal T, Naxerova K

Age distinguishes selection from causation in cancer genomes. bioRxiv. 2025;:ePub - PMID: 41279109 - PMCID: PMC12632451 - DOI: 10.1101/2025.10.06.680730