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Immune-remodeling mRNAs expressing IRF8 or NIK generate durable antitumor immunity in multiple cancer models.
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Bolli E, Wirapati P, Hicham M, Xie Y, Siwicki M, Duval F, Goubet AG, Kiss M, Zitti B, Zwahlen T, Mcdowell S, Bill R, Angerani S, Engblom C, Anderson S, Jiang A, Hartley O, Sykes DB, Jankovic M, Fournier N, Gunzer M, Tarussio D, Tissot S, Sadow PM, Faquin WC, Sade-Feldman M, Weissleder R, Pai S, Mercier F, Manguso R, Pittet MJ

CCL3 is produced by aged neutrophils across cancers and promotes tumor growth.
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Rabinowitz Z, Deutsch-Williams RJ, Weissleder R

Erasable FAP Targeted Spray-On Probe for Fluorescence-Guided Surgery.
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Kim HS, Oh J, Jeon J, Fei F, Parvanian S, Kohler R, Garris C, Weissleder R

A ribonucleotide carbohydrate system (iRNC) enhances antigen presentation and controls glioblastoma.
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Iqbal S, Hegde K, Arellano R, Uppot R, Zhao S, An T, Ellis H, Weissleder R

Percutaneous Endobiliary Radiofrequency Ablation (PERFA) for Unresectable Cholangiocarcinoma.
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Zong C, Lim K, Walker SA, Dai R, Jeong MH, George R, Jo JH, Iqbal S, Im H, Weissleder R

Do drugs with biliary toxicity cause cholangiocarcinoma?
bioRxiv. 2026;:ePub - PMID: 41959498 - PMCID: PMC13060385 - DOI: 10.64898/2026.03.31.715688
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