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Imaging in the era of molecular oncology Nature. 2008;452:580-589 - PMID: 18385732 - PMCID: PMC2708079 - DOI: 10.1038/nature06917

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Magnetic relaxation switches capable of sensing molecular interactions Nat Biotechnol. 2002;20:816-20 - PMID: 12134166 - DOI: 10.1038/nbt720

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Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells Nat Biotechnol. 2000;18:410-4 - PMID: 10748521 - DOI: 10.1038/74464

Weissleder R, Tung CH, Mahmood U, Bogdanov A Jr

In vivo imaging of tumors with protease-activated near-infrared fluorescent probes Nat Biotechnol. 1999;17:375-8 - PMID: 10207887 - DOI: 10.1038/7933

Ntziachristos V, Ripoll J, Wang L, Weissleder R

Looking and Listening to light: the evolution of whole-body photonic imaging Nat Biotechnol. 2005;23:313-320 - PMID: 15765087 - DOI: 10.1038/nbt1074

Weissleder R, Kelly K, Sun E, Shtatland T, Josephson L.

Cell-specific targeting of nanoparticles by multivalent attachment of small molecules Nat Biotechnol. 2005;23:1418-1423 - PMID: 16244656 - DOI: 10.1038/nbt1159

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Metabolic Biotinylation of Cell Surface Receptors for in vivo Imaging Nat Methods. 2006;3(5):391-396 - PMID: 16628210 - DOI: 10.1038/nmeth875

Vinegoni C, Pitsouli C, Razansky D, Perrimon N, Ntziachristos V

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Wurdinger T, Badr C, Pike L, de Kleine R, Weissleder R, Breakefield XO, Tannous BA

A secreted luciferase for ex vivo monitoring of in vivo processes. Nat Methods. 2008;5:171-173 - PMID: 18204457 - PMCID: PMC2699561 - DOI: 10.1038/nmeth.1177

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Therapeutic stem-cells for cancer treatment: hopes and hurdles in tactical warfare. Lancet Oncol. 2008;9(4):376-84 - PMID: 18374291 - DOI: 10.1016/S1470-2045(08)70099-8

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Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA

Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis Cancer Cell. 2002;1:269-77 - PMID: 12086863 - DOI: 10.1016/s1535-6108(02)00046-6

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The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell. 2006;9(6):485-95 - PMID: 16730237 - DOI: 10.1016/j.ccr.2006.04.022

Wurdinger T, Tannous BA, Saydam O, Skog J, Grau S, Soutschek J, Weissleder R, Breakefield XO, Krichevsky AM

miR-296 Regulates Growth Factor Receptor Overexpression in Angiogenic Endothelial Cells. Cancer Cell. 2008;14(5):382-393 - PMID: 18977327 - PMCID: PMC2597164 - DOI: 10.1016/j.ccr.2008.10.005

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Molecular Imaging in Cancer Science. 2006;312:1168-1171 - PMID: 16728630 - DOI: 10.1126/science.1125949

Shaw S, Wang J

Knotting of a DNA chain during ring closure. Science. 1993;260(5107):533-6 - PMID: 8475384 - DOI: 10.1126/science.8475384

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Optical coherence tomography. Science. 1991;254:1178-81 - PMID: 1957169 - PMCID: PMC4638169 - DOI: 10.1126/science.1957169

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The structure of haplotype blocks in the human genome. Science. 2002;296(5576):2225-9 - PMID: 12029063 - DOI: 10.1126/science.1069424

Reich DE, Schaffner SF, Daly MJ, McVean G, Mullikin JC, Higgins JM, Richter DJ, Lander ES, Altshuler D

Human genome sequence variation and the influence of gene history, mutation and recombination. Nat Genet. 2002;32(1):135-42 - PMID: 12161752 - DOI: 10.1038/ng947

Reiser J, Polu KR, Moller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR

TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005;37(7):739-44 - PMID: 15924139 - PMCID: PMC1360984 - DOI: 10.1038/ng1592

Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, Lin HY

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006;38(5):531-9 - PMID: 16604073 - DOI: 10.1038/ng1777

Nahrendorf M, Aikawa E, Figueiredo JL, Stangenberg L, van den Borne S, Blankesteijn M, Sosnovik D, Jaffer F, Tung CH, Weissleder R

Transglutaminase activity in acute infarcts predicts healing outcome and let ventricular remodelling : implications for FXIII therapy and antithrombin use in myocardial infarction Eur Heart J. 2008;29:445-454 - PMID: 18276618 - DOI: 10.1093/eurheartj/ehm558

Rabin O, Manuel Perez J, Grimm J, Wojtkiewicz G, Weissleder R

An X-ray computed tomography imaging agent based on long-circulating bismuth sulphide nanoparticles. Nat Mater. 2006;5(2):118-22 - PMID: 16444262 - DOI: 10.1038/nmat1571

Marten K, Bremer C, Khazaie K, Sameni M, Sloane B, Tung CH, Weissleder R

Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice Gastroenterology. 2002;122:406-14 - PMID: 11832455 - DOI: 10.1053/gast.2002.30990

Mahmood U, Wallace MB

Molecular imaging in gastrointestinal disease. Gastroenterology. 2007;132(1):11-4 - PMID: 17241854 - DOI: 10.1053/j.gastro.2006.12.013

Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K

Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity. Gastroenterology. 2008;134(4):1028-37 - PMID: 18395084 - DOI: 10.1053/j.gastro.2008.01.070

Rudin M, Weissleder R

Molecular imaging in drug discovery and development Nat Rev Drug Discov. 2003;2:123-31 - PMID: 12563303 - DOI: 10.1038/nrd1007

Im H, Huang XJ, Gu B, Choi YK

A dielectric-modulated field-effect transistor for biosensing. Nat Nanotechnol. 2007;2(7):430-4 - PMID: 18654328 - DOI: 10.1038/nnano.2007.180

Jaffer F, Weissleder R

Molecular Imaging in the Clinical Arena JAMA. 2005;293(7):855-62 - PMID: 15713776 - DOI: 10.1001/jama.293.7.855

Weissleder R, Ntziachristos V

Shedding light onto live molecular targets Nature Med. 2003;9:123-8 - PMID: 12514725 - DOI: 10.1038/nm0103-123

Ntziachristos V, Tung CH, Bremer C, Weissleder R

Fluorescence molecular tomography resolves protease activity in vivo Nature Med. 2002;8:757-60 - PMID: 12091907 - DOI: 10.1038/nm729

Bremer C, Tung CH, Weissleder R

In vivo molecular target assessment of matrix metalloproteinase inhibition Nature Med. 2001;7:743-8 - PMID: 11385514 - DOI: 10.1038/89126

Weissleder R, Moore A, Mahmood U, Bhorade R, Benveniste H, Chiocca EA, Basilion JP

In vivo magnetic resonance imaging of transgene expression Nature Med. 2000;6:351-5 - PMID: 10700241 - DOI: 10.1038/73219

Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T

A spatially and temporally restricted mouse model of soft tissue sarcoma. Nature Med. 2007;13(8):992-997 - PMID: 17676052 - DOI: 10.1038/nm1602

Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone. Nature Med. 2008;14(2):181-7 - PMID: 18193058 - DOI: 10.1038/nm1703

Kaushal S, Amiel G, Guleserian K, Shapira O, Perry T, Sutherland F, Rabkin E, Moran A, Schoen F, Atala A, Soker S, Bischoff J, Mayer J

Functional small-diameter neovessels created using endothelial progenitor cells expanded ex vivo. Nature Med. 2001;7:1035-40 - PMID: 11533707 - PMCID: PMC2818999 - DOI: 10.1038/nm0901-1035

Shimizu K, Sugiyama S, Aikawa M, Fukumoto Y, Rabkin E, Libby P, Mitchell R

Host bone-marrow cells are a source of donor intimal smooth- muscle-like cells in murine aortic transplant arteriopathy. Nature Med. 2001;7:738-41 - PMID: 11385513 - DOI: 10.1038/89121

Lee H, Sun E, Ham D, Weissleder R

Chip-NMR biosensor for detection and molecular analysis of cells. Nature Med. 2008;14(8):869-74 - PMID: 18607350 - PMCID: PMC2729055 - DOI: 10.1038/nm.1711

Engelman JA, Chen L, Tan X, Crosby K, Guimaraes AR, Upadhyay R, Maira M, McNamara K, Perera SA, Song Y, Chirieac LR, Kaur R, Lightbown A, Simendinger J, Li T, Padera RF, Garcia-Echeverria C, Weissleder R, Mahmood U, Cantley LC, Wong KK

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nature Med. 2008;14(12)::1351-1356 - PMID: 19029981 - PMCID: PMC2683415 - DOI: 10.1038/nm.1890

Dagia N, Gadhoum S, Knoblauch C, Spencer J, Zamiri P, Lin CP, Sackstein R

G-CSF induces E-selectin ligand expression on human myeloid cells. Nature Med. 2006;12:1185-90 - PMID: 16980970 - DOI: 10.1038/nm1470

Breton S, Smith PJ, Lui B, Brown D

Acidification of the male reproductive tract by a proton pumping (H+)-ATPase. Nature Med. 1996;2(4):470-2 - PMID: 8597961 - DOI: 10.1038/nm0496-470

Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R

In vivo imaging of proteolytic activity in atherosclerosis Circulation. 2002;105:2766-71 - PMID: 12057992 - DOI: 10.1161/01.cir.0000017860.20619.23

Jaffer FA, Tung CH, Wykrzykowska JJ, Ho NH, Houng AK, Reed GL, Weissleder R

Molecular Imaging of Factor XIIIa Activity in Thrombosis Using a Novel, Near-Infrared Fluorescent Contrast Agent That Covalently Links to Thrombi. Circulation. 2004;110(2):170-6 - PMID: 15210587 - DOI: 10.1161/01.CIR.0000134484.11052.44

Chen J, Tung CH, Allport JR, Chen S, Weissleder R, Huang PL.

Near-Infrared Fluorescent Imaging of Matrix Metalloproteinase Activity After Myocardial Infarction Circulation. 2005;111:1800-1805 - PMID: 15809374 - PMCID: PMC3733536 - DOI: 10.1161/01.CIR.0000160936.91849.9F

Nahrendorf M, Hu K, Frantz S, Jaffer F, Tung CH, Hiller KH, Voll S, Nordbeck P, Sosnovik D, Gattenlohner S, Novikov M, Dickneite G, Reed G, Jakob P, Rosenzweig A, Bauer W, Weissleder R, Ertl G.

Factor XIII Deficiency Causes Cardiac Rupture, Impairs Wound Healing, and Aggravates Cardiac Remodeling in Mice with Myocardial Infarction Circulation. 2006;113(9):1196-1202 - PMID: 16505171 - PMCID: PMC4066325 - DOI: 10.1161/CIRCULATIONAHA.105.602094

Heller EA, Liu E, Tager AM, Yuan Q, Lin AY, Ahluwalia N, Jones K, Koehn SL, Lok VM, Aikawa E, Moore KJ, Luster AD, Gerszten RE

Chemokine CXCL10 Promotes Atherogenesis by Modulating the Local Balance of Effector and Regulatory T Cells. Circulation. 2006;113(19):2301-12 - PMID: 16682613 - DOI: 10.1161/CIRCULATIONAHA.105.605121

Deguchi JO, Aikawa M, Tung CH, Aikawa E, Kim DE, Ntziachristos V, Weissleder R, Libby P

Inflammation in Atherosclerosis. Visualizing Matrix Metalloproteinase Action in Macrophages In Vivo. Circulation. 2006;114:55-62 - PMID: 16801460 - DOI: 10.1161/CIRCULATIONAHA.106.619056

Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R

Noninvasive Vascular Cell Adhesion Molecule-1 Imaging Identifies Inflammatory Activation of Cells in Atherosclerosis. Circulation. 2006;114:1504-1511 - PMID: 17000904 - DOI: 10.1161/CIRCULATIONAHA.106.646380

Aikawa E, Nahrendorf M, Sosnovik D, Lok VM, Jaffer FA, Aikawa M, Weissleder R

Multimodality Molecular Imaging Identifies Proteolytic and Osteogenic Activities in Early Aortic Valve Disease. Circulation. 2007;115:377-386 - PMID: 17224478 - DOI: 10.1161/CIRCULATIONAHA.106.654913

Sosnovik DE, Nahrendorf M, Deliolanis N, Novikov M, Aikawa E, Josephson L, Rosenzweig A, Weissleder R, Ntziachristos V

Fluorescence Tomography and Magnetic Resonance Imaging of Myocardial Macrophage Infiltration in Infarcted Myocardium In Vivo. Circulation. 2007;115:1384-1391 - PMID: 17339546 - DOI: 10.1161/CIRCULATIONAHA.106.663351

Jaffer FA, Kim DE, Quinti L, Tung CH, Aikawa E, Pande AN, Kohler RH, Shi GP, Libby P, Weissleder R

Optical Visualization of Cathepsin K Activity in Atherosclerosis With a Novel, Protease-Activatable Fluorescence Sensor. Circulation. 2007;115(17):2292-8 - PMID: 17420353 - DOI: 10.1161/CIRCULATIONAHA.106.660340

Sosnovik DE, Nahrendorf M, Weissleder R

Molecular magnetic resonance imaging in cardiovascular medicine. Circulation. 2007;115(15):2076-86 - PMID: 17438163 - DOI: 10.1161/CIRCULATIONAHA.106.658930

Jaffer FA, Libby P, Weissleder R

Molecular imaging of cardiovascular disease. Circulation. 2007;116(9):1052-61 - PMID: 17724271 - DOI: 10.1161/CIRCULATIONAHA.106.647164

Aikawa E, Nahrendorf M, Figueiredo JL, Swirski F, Shtatland T, Kohler RH, Jaffer F, Aikawa M, Weissleder R.

Osteogenesis associates with inflammation in early-stage atherosclerosis evaluated by molecular imaging in vivo. Circulation. 2007;116(24):2841-50 - PMID: 18040026 - DOI: 10.1161/CIRCULATIONAHA.107.732867

Nahrendorf M, Zhang H, Hembrador S, Panizzi P, Sosnovik D, Aikawa E, Libby P, Swirski F, Weissleder R.

Nanoparticle PET-CT imaging of macrophages in inflammatory atherosclerosis Circulation. 2007;117:379-387 - PMID: 18158358 - PMCID: PMC2663426 - DOI: 10.1161/CIRCULATIONAHA.107.741181

Kircher M, Grimm J, Swirski FK, Libby P, Gerszten R, Allport J, Weissleder R

Noninvasive in vivo imaging of monocyte trafficking to atherosclerotic lesions. Circulation. 2008;117:388-395 - PMID: 18172031 - PMCID: PMC2705289 - DOI: 10.1161/CIRCULATIONAHA.107.719765

Nahrendorf M*, Sosnovik D*, Chen JW, Panizzi P, Figueiredo JL, Aikawa E, Libby P, Swirski FK, Weissleder R

Activatable Magnetic Resonance Imaging Agent Reports Myeloperoxidase Activity in Healing Infarcts and Noninvasively Detects the Antiinflammatory Effects of Atorvastatin on Ischemia-Reperfusion Injury. Circulation. 2008;117(9):1153-60 - PMID: 18268141 - PMCID: PMC2673051 - DOI: 10.1161/CIRCULATIONAHA.107.756510

Libby P, Nahrendorf M, Pittet MJ, Swirski FK

Diversity of denizens of the atherosclerotic plaque: not all monocytes are created equal. Circulation. 2008;117(25):3168-70 - PMID: 18574058 - DOI: 10.1161/CIRCULATIONAHA.108.783068

Aikawa E, Whittaker P, Farber M, Mendelson K, Padera R, Aikawa M, Schoen F

Human semilunar cardiac valve remodeling by activated cells from fetus to adult: implications for postnatal adaptation, pathology, and tissue engineering. Circulation. 2006;113:1344-52 - PMID: 16534030 - DOI: 10.1161/CIRCULATIONAHA.105.591768

Aikawa M, Sugiyama S, Hill C, Voglic S, Rabkin E, Fukumoto Y, Schoen F, Witztum J, Libby P

Lipid lowering reduces oxidative stress and endothelial cell activation in rabbit atheroma. Circulation. 2002;106:1390-6 - PMID: 12221058 - DOI: 10.1161/01.cir.0000028465.52694.9b

Deguchi J, Aikawa E, Libby P, Vachon J, Inada M, Krane S, Whittaker P, Aikawa M

Matrix metalloproteinase-13/collagenase-3 deletion promotes collagen accumulation and organization in mouse atherosclerotic plaques. Circulation. 2005;112:2708-15 - PMID: 16230484 - DOI: 10.1161/CIRCULATIONAHA.105.562041

Lindsey M, Gannon J, Aikawa M, Schoen F, Rabkin E, Lopresti-Morrow L, Crawford J, Black S, Libby P, Mitchell P, Lee R

Selective matrix metalloproteinase inhibition reduces left ventricular remodeling but does not inhibit angiogenesis after myocardial infarction. Circulation. 2002;105:753-8 - PMID: 11839633 - DOI: 10.1161/hc0602.103674

Larose E, Yeghiazarians Y, Libby P, Yucel E, Aikawa M, Kacher D, Aikawa E, Kinlay S, Schoen F, Selwyn A, Ganz P

Characterization of human atherosclerotic plaques by intravascular magnetic resonance imaging. Circulation. 2005;112:2324-31 - PMID: 16203910 - DOI: 10.1161/CIRCULATIONAHA.105.538942

Heller E, Liu E, Tager A, Sinha S, Roberts J, Koehn S, Libby P, Aikawa E, Chen J, Huang P, Freeman M, Moore K, Luster A, Gerszten R

Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment. Circulation. 2005;112:578-86 - PMID: 16043658 - DOI: 10.1161/CIRCULATIONAHA.105.545616

Sutherland F, Perry T, Yu Y, Sherwood M, Rabkin E, Masuda Y, Garcia G, McLellan D, Engelmayr G, Sacks M, Schoen F, Mayer J

From stem cells to viable autologous semilunar heart valve. Circulation. 2005;111:2783-91 - PMID: 15927990 - DOI: 10.1161/CIRCULATIONAHA.104.498378

Fukumoto Y, Deguchi J, Libby P, Rabkin-Aikawa E, Sakata Y, Chin M, Hill C, Lawler P, Varo N, Schoen F, Krane S, Aikawa M

Genetically determined resistance to collagenase action augments interstitial collagen accumulation in atherosclerotic plaques. Circulation. 2004;110:1953-9 - PMID: 15451791 - DOI: 10.1161/01.CIR.0000143174.41810.10

Waller C, Hiller K, Kahler E, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer W

Serial magnetic resonance imaging of microvascular remodeling in the infarcted rat heart. Circulation. 2001;103(11):1564-9 - PMID: 11257086 - DOI: 10.1161/01.cir.103.11.1564

Rabkin E, Aikawa M, Stone J, Fukumoto Y, Libby P, Schoen F

Activated interstitial myofibroblasts express catabolic enzymes and mediate matrix remodeling in myxomatous heart valves. Circulation. 2001;104:2525-32 - PMID: 11714645 - DOI: 10.1161/hc4601.099489

Aikawa M, Rabkin E, Sugiyama S, Voglic S, Fukumoto Y, Furukawa Y, Shiomi M, Schoen F, Libby P

An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro. Circulation. 2001;103:276-83 - PMID: 11208689 - DOI: 10.1161/01.cir.103.2.276

Fukumoto Y, Libby P, Rabkin E, Hill C, Enomoto M, Hirouchi Y, Shiomi M, Aikawa M

Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits. Circulation. 2001;103:993-9 - PMID: 11181475 - DOI: 10.1161/01.cir.103.7.993

Aikawa M, Voglic S, Sugiyama S, Rabkin E, Taubman M, Fallon J, Libby P

Dietary lipid lowering reduces tissue factor expression in rabbit atheroma. Circulation. 1999;100:1215-22 - PMID: 10484543 - DOI: 10.1161/01.cir.100.11.1215

Aikawa M, Rabkin E, Okada Y, Voglic S, Clinton S, Brinckerhoff C, Sukhova G, Libby P

Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization. Circulation. 1998;97:2433-44 - PMID: 9641696 - DOI: 10.1161/01.cir.97.24.2433

Nakagawa T, Sukhova G, Rabkin E, Winters G, Schoen F, Libby P

Acute rejection accelerates graft coronary disease in transplanted rabbit hearts. Circulation. 1995;92:987-93 - PMID: 7641383 - DOI: 10.1161/01.cir.92.4.987

Jaffer FA, Vinegoni C, John MC, Aikawa E, Gold HK, Finn AV, Ntziachristos V, Libby P, Weissleder R

Real-Time Catheter Molecular Sensing of Inflammation in Proteolytically Active Atherosclerosis. Circulation. 2008;118(18):1802-9 - PMID: 18852366 - PMCID: PMC2729441 - DOI: 10.1161/CIRCULATIONAHA.108.785881

Mahmood U

Near infrared optical applications in molecular imaging. Earlier, more accurate assessment of disease presence, disease course, and efficacy of disease treatment. IEEE Eng Med Biol. 2004;23(4):58-66 - PMID: 15508386 - DOI: 10.1109/memb.2004.1337950

Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D

Arthritis critically dependent on innate immune system players Immunity. 2002;16:157-68 - PMID: 11869678 - DOI: 10.1016/s1074-7613(02)00275-3

Mempel T, Pittet M, Khazaie K, Weninger W, Weissleder R, von Boehmer H, von Adrian U.

Regulatory T cells reversibly suppress cytotoxic T cell function independent of effector differentiation Immunity. 2006;25(1):129-41 - PMID: 16860762 - DOI: 10.1016/j.immuni.2006.04.015

Gounari F, Chang R, Cowan J, Guo Z, Dose M, Gounaris E, Khazaie K.

Loss of adenomatous polyposis coli gene function disrupts thymic development Nat Immunol. 2005;6(8):800-9 - PMID: 16025118 - PMCID: PMC4662936 - DOI: 10.1038/ni1228

Binstadt BA, Patel PR, Alencar H, Nigrovic PA, Lee DM, Mahmood U, Weissleder R, Mathis D, Benoist C

Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat Immunol. 2006;7(3):284-92 - PMID: 16444258 - DOI: 10.1038/ni1306

Alsayed Y, Ngo H, Runnels J, Leleu X, Singha UK, Pitsillides CM, Spencer JA, Kimlinger T, Ghobrial JM, Jia X, Lu G, Timm M, Kumar A, Cote D, Veilleux I, Hedin KE, Roodman GD, Witzig TE, Kung AL, Hideshima T, Anderson KC, Lin CP, Ghobrial IM

Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma. Blood. 2007;109:2708-17 - PMID: 17119115 - PMCID: PMC1852222 - DOI: 10.1182/blood-2006-07-035857

Leleu X, Jia X, Runnels J, Ngo HT, Moreau AS, Farag M, Spencer JA, Pitsillides CM, Hatjiharissi E, Roccaro A, O'Sullivan G, McMillin DW, Moreno D, Kiziltepe T, Carrasco R, Treon SP, Hideshima T, Anderson KC, Lin CP, Ghobrial IM

The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia. Blood. 2007;110:4417-26 - PMID: 17761832 - PMCID: PMC2234792 - DOI: 10.1182/blood-2007-05-092098

Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood. 2008;111(10):5195-204 - PMID: 18326817 - PMCID: PMC2384142 - DOI: 10.1182/blood-2007-09-111567

Rufer N, Zippelius A, Batard P, Pittet M, Kurth I, Corthesy P, Cerottini J, Leyvraz S, Roosnek E, Nabholz M, Romero P

Ex vivo characterization of human CD8+ T subsets with distinct replicative history and partial effector functions. Blood. 2003;102:1779-87 - PMID: 12750165 - DOI: 10.1182/blood-2003-02-0420

Kerre T, De Smet G, De Smedt M, Zippelius A, Pittet M, Langerak A, De Bosscher J, Offner F, Vandekerckhove B, Plum J

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells. Blood. 2002;99:1620-6 - PMID: 11861276 - DOI: 10.1182/blood.v99.5.1620

Kunstfeld R, Hirakawa S, Hong Y-K, Schacht V, Lange-Asschenfeldt B, Velasco P, Lin CP, Fiebiger E, Wu Y, Hicklin D, Bohlen P, Detmar M

VEGF-A overexpression leads to lymphatic vessel enlargement and persistent skin inflammation Blood. 2004;104:1048-57

Higgins JM, Sloan SR

Stochastic modeling of human RBC alloimmunization: evidence for a distinct population of immunologic responders. Blood. 2008;112(6):2546-53 - PMID: 18535200 - DOI: 10.1182/blood-2008-03-146415

Mosley AJ, Meekings KN, McCarthy C, Shepherd D, Cerundolo V, Mazitschek R, Tanaka Y, Taylor GP, Bangham CR

Histone deacetylase inhibitors increase virus gene expression but decrease CD8+ cell antiviral function in HTLV-1 infection. Blood. 2006;108(12):3801-7 - PMID: 16912225 - DOI: 10.1182/blood-2006-03-013235

Nicolaou F, Teodoridis JM, Park H, Georgakis A, Farokhzad OC, Böttinger EP, Da Silva N, Rousselot P, Chomienne C, Ferenczi K, Arnaout MA, Shelley CS

CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD. Blood. 2003;101(10):4033-41 - PMID: 12576324 - DOI: 10.1182/blood-2002-01-0324

Da Silva N, Bharti A, Shelley CS

hnRNP-K and Pur(alpha) act together to repress the transcriptional activity of the CD43 gene promoter. Blood. 2002;100(10):3536-44 - PMID: 12411317 - DOI: 10.1182/blood.V100.10.3536

Hurtado-Lorenzo A, Skinner M, El Annan J, Futai M, Sun-Wada GH, Bourgoin S, Casanova J, Wildeman A, Bechoua S, Ausiello DA, Brown D, Marshansky V

V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway. Nat Cell Biol. 2006;8(2):124-36 - PMID: 16415858 - DOI: 10.1038/ncb1348

Jaffer F, Libby P, Weissleder R.

Molecular and Cellular Imaging of Atherosclerosis, Emerging Applications J Am Coll Cardiol. 2006;47:1328-1338 - PMID: 16580517 - DOI: 10.1016/j.jacc.2006.01.029

Nahrendorf M, Hu K, Hiller K, Galuppo P, Fraccarollo D, Schweizer G, Haase A, Ertl G, Bauer W, Bauersachs J

Impact of hydroxymethylglutaryl coenzyme a reductase inhibition on left ventricular remodeling after myocardial infarction: an experimental serial cardiac magnetic resonance imaging study. J Am Coll Cardiol. 2002;40(9):1695-700 - PMID: 12427425 - DOI: 10.1016/s0735-1097(02)02375-6

Korosoglou G, Weiss RG, Kedziorek DA, Walczak P, Gilson WD, Schar M, Sosnovik DE, Kraitchman DL, Boston RC, Bulte JW, Weissleder R, Stuber M

Noninvasive detection of macrophage-rich atherosclerotic plaque in hyperlipidemic rabbits using positive contrast magnetic resonance imaging. J Am Coll Cardiol. 2008;52:483-91 - PMID: 18672170 - PMCID: PMC2628468 - DOI: 10.1016/j.jacc.2008.03.063

Shah K, Tung CH, Chang CH, Slootweg E, O'Loughlin T, Breakefield XO, Weissleder R

In vivo imaging of HIV protease activity in amplicon vector-transduced gliomas Cancer Res. 2004;64:273-8 - PMID: 14729634 - DOI: 10.1158/0008-5472.can-03-1123

Grimm J, Perez JM, Josephson L, Weissleder R

Novel nanosensors for rapid analysis of telomerase activity Cancer Res. 2004;64:639-43 - PMID: 14744779 - DOI: 10.1158/0008-5472.can-03-2798

Zhao M, Josephson L, Tang Y, Weissleder R

Magnetic sensors for protease assays Angew Chem Int Ed Engl. 2003;42:1375-8 - PMID: 12671972 - DOI: 10.1002/anie.200390352

Petrovsky A, Schellenberger E, Josephson L, Weissleder R, Bogdanov A Jr

Near-infrared fluorescent imaging of tumor apoptosis Cancer Res. 2003;63:1936-42 - PMID: 12702586

Kircher MF, Allport, JR, Graves EE, Love V, Josephson L, Lichtman AH, Weissleder R

In vivo high resolution three-dimensional imaging of antigen-specific cytotoxic T-lymphocyte trafficking to tumors Cancer Res. 2003;63:6838-46 - PMID: 14583481

Kircher MF, Mahmood U, King RS, Weissleder R, Josephson L

A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation Cancer Res. 2003;63:8122-5 - PMID: 14678964

Pham W, Weissleder R, Tung CH

An azulene dimer as a near-infrared quencher Angew Chem Int Ed Engl. 2002;41:3659-62, 3519 - PMID: 12370922 - DOI: 10.1002/1521-3773(20021004)41:19<3659::AID-ANIE3659>3.0.CO;2-Q

Tung CH, Mahmood U, Bredow S, Weissleder R

In vivo imaging of proteolytic enzyme activity using a novel molecular reporter Cancer Res. 2000;60:4953-8 - PMID: 10987312

Simonova M, Wall A, Weissleder R, Bogdanov A Jr

Tyrosinase mutants are capable of prodrug activation in transfected nonmelanotic cells Cancer Res. 2000;60:6656-62 - PMID: 11118049

Tung CH, Zeng Q, Shah K, Kim DE, Schellingerhout D, Weissleder R

In Vivo Imaging of ?-Galactosidase Activity Using Far Red Fluorescent Switch Cancer Res. 2004;64:1579-1583 - PMID: 14996712 - DOI: 10.1158/0008-5472.can-03-3226

Tsourkas A, Hofstetter O, Hofstetter H, Weissleder R, Josephson L

Magnetic Relaxation Switch Immunosensors Detect Enantiomeric Impurities Angew Chem Int Ed Engl. 2004;43(18):2395-2399 - PMID: 15114571 - DOI: 10.1002/anie.200352998

Shah K, Tung CH, Yang K, Weissleder R, Breakefield XO

Inducible release of TRAIL fusion proteins from a proapoptotic form for tumor therapy Cancer Res. 2004;64(9):3236-42 - PMID: 15126365 - DOI: 10.1158/0008-5472.can-03-3516

Gondi CS, Lakka SS, Yanamandra N, Olivero WC, Dinh DH, Gujrati M, Tung CH, Weissleder R, Rao JS

Adenovirus-mediated expression of antisense urokinase plasminogen activator receptor and antisense cathepsin B inhibits tumor growth, invasion, and angiogenesis in gliomas. Cancer Res. 2004;64(12):4069-77 - PMID: 15205313 - DOI: 10.1158/0008-5472.CAN-04-1243

Kelly K, Alencar H, Funovics M, Mahmood U, Weissleder R

Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide. Cancer Res. 2004;64(17):6247-51 - PMID: 15342411 - DOI: 10.1158/0008-5472.CAN-04-0817

Montet X, Ntziachristos V, Grimm J, Weissleder R.

Tomographic Fluorescence Mapping of Tumor Targets Cancer Res. 2005;65 (14):6330-6336 - PMID: 16024635 - DOI: 10.1158/0008-5472.CAN-05-0382

Tang Y, Kim M, Carrasco D, Kung AL, Chin L, Weissleder R.

In vivo assessment of RAS-dependent maintenance of tumor angiogenesis by real-time magnetic resonance imaging Cancer Res. 2005;65(18):8324-30 - PMID: 16166309 - DOI: 10.1158/0008-5472.CAN-05-0027

Kim YR, Yudina A, Figueiredo J, Reichardt W, Hu-Lowe D, Petrovsky A, Kang HW, Torres D, Mahmood U, Weissleder R, Bogdanov AA Jr.

Detection of Early Antiangiogenic Effects in Human Colon Adenocarcinoma Xenografts: In vivo Changes of Tumor Blood Volume in Response to Experimental VEGFR Tyrosine Kinase Inhibitor Cancer Res. 2005;65(20):9253-60 - PMID: 16230386 - DOI: 10.1158/0008-5472.CAN-03-2619

Choi YD, Weissleder R, Tung CH.

Selective antitumor effect of novel protease-mediated photodynamic agent Cancer Res. 2006;66 (14):7225-7229 - PMID: 16849570 - DOI: 10.1158/0008-5472.CAN-06-0448

Arwert E, Hingtgen S, Figueiredo JL, Bergquist H, Mahmood U, Weissleder R, Shah K.

Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo Cancer Res. 2007;67 (15):7335-7342 - PMID: 17671203 - DOI: 10.1158/0008-5472.CAN-07-0077

Corsten MF, Miranda R, Kasmieh R, Krichevsky AM, Weissleder R, Shah K

MicroRNA-21 Knockdown Disrupts Glioma Growth In vivo and Displays Synergistic Cytotoxicity with Neural Precursor Cell Delivered S-TRAIL in Human Gliomas. Cancer Res. 2007;67(19):8994-9000 - PMID: 17908999 - DOI: 10.1158/0008-5472.CAN-07-1045

Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, van Rooijen N, Rachamimov AS, Hochberg FH, Weissleder R, Martuza RL, Chiocca EA

Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses. Cancer Res. 2007;67(19):9398-406 - PMID: 17909049 - PMCID: PMC2850558 - DOI: 10.1158/0008-5472.CAN-07-1063

Kelly KA, Setlur SR, Ross R, Anbazhagan R, Waterman P, Rubin MA, Weissleder R

Detection of early prostate cancer using a hepsin-targeted imaging agent. Cancer Res. 2008;68(7):2286-91 - PMID: 18381435 - PMCID: PMC2709884 - DOI: 10.1158/0008-5472.CAN-07-1349

Koh I, Hong R, Weissleder R, Josephson L

Sensitive NMR Sensors Detect Antibodies to Influenza. Angew Chem Int Ed Engl. 2008;47(22):4119-4121 - PMID: 18428168 - PMCID: PMC2668198 - DOI: 10.1002/anie.200800069

Zippelius A, Batard P, Rubio-Godoy V, Bioley G, Lienard D, Lejeune F, Rimoldi D, Guillaume P, Meidenbauer N, Mackensen A, Rufer N, Lubenow N, Speiser D, Cerottini J, Romero P, Pittet M

Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance. Cancer Res. 2004;64:2865-73 - PMID: 15087405 - DOI: 10.1158/0008-5472.can-03-3066

Meidenbauer N, Zippelius A, Pittet M, Laumer M, Vogl S, Heymann J, Rehli M, Seliger B, Schwarz S, Le Gal F, Dietrich P, Andreesen R, Romero P, Mackensen A

High frequency of functionally active Melan-a-specific T cells in a patient with progressive immunoproteasome-deficient melanoma. Cancer Res. 2004;64:6319-26 - PMID: 15342421 - DOI: 10.1158/0008-5472.CAN-04-1341

Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Lienard D, Gugerli O, Ferradini L, Robert C, Avril M, Zitvogel L, Angevin E

Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma. Cancer Res. 2004;64:2192-8 - PMID: 15026362 - DOI: 10.1158/0008-5472.can-03-2969

Valmori D, Pittet M, Vonarbourg C, Rimoldi D, Lienard D, Speiser D, Dunbar R, Cerundolo V, Cerottini J, Romero P

Analysis of the cytolytic T lymphocyte response of melanoma patients to the naturally HLA-A*0201-associated tyrosinase peptide 368-376. Cancer Res. 1999;59:4050-5 - PMID: 10463606

Valmori D, Dutoit V, Lienard D, Rimoldi D, Pittet M, Champagne P, Ellefsen K, Sahin U, Speiser D, Lejeune F, Cerottini J, Romero P

Naturally occurring human lymphocyte antigen-A2 restricted CD8+ T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients. Cancer Res. 2000;60:4499-506 - PMID: 10969798

Valmori D, Pittet M, Rimoldi D, Lienard D, Dunbar R, Cerundolo V, Lejeune F, Cerottini J, Romero P

An antigen-targeted approach to adoptive transfer therapy of cancer. Cancer Res. 1999;59:2167-73 - PMID: 10232604

Kelly K, Manos E, Jensen G, Nadauld L, Jones D

APRIL/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death. Cancer Res. 2000;60:1021-7 - PMID: 10706119

Georgakoudi I, Solban N, Novak J, Rice WL, Wei X, Hasan T, Lin CP

In vivo flow cytometry: a new method for enumerating circulating cancer cells. Cancer Res. 2004;64(15):5044-7 - PMID: 15289300 - PMCID: PMC2824432 - DOI: 10.1158/0008-5472.CAN-04-1058

Rosenbaum C, Baumhof P, Mazitschek R, Müller O, Giannis A, Waldmann H

Synthesis and biological evaluation of an indomethacin library reveals a new class of angiogenesis-related kinase inhibitors. Angew Chem Int Ed Engl. 2004;43(2):224-8 - PMID: 14695616 - DOI: 10.1002/anie.200352582

Huwe A, Mazitschek R, Giannis A

Small molecules as inhibitors of cyclin-dependent kinases. Angew Chem Int Ed Engl. 2003;42(19):2122-38 - PMID: 12761741 - DOI: 10.1002/anie.200200540

Stahl P, Kissau L, Mazitschek R, Giannis A, Waldmann H

Natural product derived receptor tyrosine kinase inhibitors: identification of IGF1R, Tie-2, and VEGFR-3 inhibitors. Angew Chem Int Ed Engl. 2002;41(7):1174-8 - PMID: 12491250 - DOI: 10.1002/1521-3773(20020402)41:7<1174::aid-anie1174>3.0.co;2-v

Stieber F, Mazitschek R, Soric N, Giannis A, Waldmann H

Traceless solid-phase synthesis of 2-aminothiazoles: receptor tyrosine kinase inhibitors with dual selectivity for Tie-2 and VEGFR-2. Angew Chem Int Ed Engl. 2002;41(24):4757-61 - PMID: 12481350 - DOI: 10.1002/anie.200290040

Mazitschek R, Mülbaier M, Giannis A

IBX-mediated oxidation of primary alcohols and aldehydes to form carboxylic acids. Angew Chem Int Ed Engl. 2002;41(21):4059-61 - PMID: 12412081 - DOI: 10.1002/1521-3773(20021104)41:21<4059::AID-ANIE4059>3.0.CO;2-R

Baumhof P, Mazitschek R, Giannis A

A Mild and Effective Method for the Transesterification of Carboxylic Acid Esters P.B. and R.M. are grateful to the Land Baden-Württemberg for a scholarship from the Landesgraduiertenförderung. Angew Chem Int Ed Engl. 2001;40(19):3672-3674 - PMID: 11592218 - DOI: 10.1002/1521-3773(20011001)40:19<3672::aid-anie3672>3.0.co;2-y

Wernert N, Stanjek A, Kiriakidis S, Hügel A, Jha HC, Mazitschek R, Giannis A

Inhibition of Angiogenesis In Vivo by ets-1 Antisense Oligonucleotides-Inhibition of Ets-1 Transcription Factor Expression by the Antibiotic Fumagillin. Angew Chem Int Ed Engl. 1999;38(21):3228-3231 - PMID: 10556911 - DOI: 10.1002/(sici)1521-3773(19991102)38:21<3228::aid-anie3228>3.0.co;2-8

Josephson L, Perez JM, Weissleder R

Magnetic Nanosensors for the Detection of Oligonucleotide Sequences. Angew Chem Int Ed Engl. 2001;40(17):3204-3206 - PMID: 29712059 - DOI: 10.1002/1521-3773(20010903)40:17<3204::AID-ANIE3204>3.0.CO;2-H

Kang TH, Lee JH, Song CK, Han HD, Shin BC, Pai SI, Hung CF, Trimble C, Lim JS, Kim TW, Wu TC

Epigallocatechin-3-gallate enhances CD8+ T cell-mediated antitumor immunity induced by DNA vaccination. Cancer Res. 2007;67(2):802-11 - PMID: 17234792 - PMCID: PMC3181129 - DOI: 10.1158/0008-5472.CAN-06-2638

Pai SI, Wu GS, Ozören N, Wu L, Jen J, Sidransky D, El-Deiry WS

Rare loss-of-function mutation of a death receptor gene in head and neck cancer. Cancer Res. 1998;58(16):3513-8 - PMID: 9721851

Insin N, Tracy JB, Lee H, Zimmer JP, Westervelt RM, Bawendi MG

Incorporation of iron oxide nanoparticles and quantum dots into silica microspheres. ACS Nano. 2008;2(2):197-202 - PMID: 19206619 - DOI: 10.1021/nn700344x

Jaffer FA, Weissleder R

Seeing within: molecular imaging of the cardiovascular system Circ Res. 2004;94(4):433-45 - PMID: 15001542 - DOI: 10.1161/01.RES.0000119321.18573.5A

Kelly KA, Allport JR, Tsourkas A, Shinde-Patil VR, Josephson L, Weissleder R.

Detection of Vascular Adhesion Molecule-1 Expression Using a Novel Multimodal Nanoparticle Circ Res. 2005;96(3):327-36 - PMID: 15653572 - DOI: 10.1161/01.RES.0000155722.17881.dd

Nahrendorf M, Sosnovik D, Waterman P, Swirski F, Pande A, Aikawa E, Figueiredo JL, Pittet M, Weissleder R.

Dual channel optical tomographic imaging of leukocyte recruitment and protease activity in the healing myocardial infarct Circ Res. 2007;100:1218-1225 - PMID: 17379832 - DOI: 10.1161/01.RES.0000265064.46075.31

Paruchuri S, Yang J, Aikawa E, Melero-Martin J, Khan Z, Loukogeorgakis S, Schoen F, Bischoff J

Human Pulmonary Valve Progenitor Cells Exhibit Endothelial/Mesenchymal Plasticity in Response to Vascular Endothelial Growth Factor-A and Transforming Growth Factor-{beta}2. Circ Res. 2006;99(8):861-9 - PMID: 16973908 - PMCID: PMC2810464 - DOI: 10.1161/01.RES.0000245188.41002.2c

Aikawa M, Rabkin E, Voglic S, Shing H, Nagai R, Schoen F, Libby P

Lipid lowering promotes accumulation of mature smooth muscle cells expressing smooth muscle myosin heavy chain isoforms in rabbit atheroma. Circ Res. 1998;83:1015-26 - PMID: 9815149 - DOI: 10.1161/01.res.83.10.1015

Perez JM, Simeone FJ, Saeki Y, Josephson L, Weissleder R

Viral-induced self-assembly of magnetic nanoparticles allows the detection of viral particles in biological media J Am Chem Soc. 2003;125:10192-3 - PMID: 12926940 - DOI: 10.1021/ja036409g

Perez JM, O'Loughin T, Simeone F J, Weissleder R, Josephson L

DNA-based magnetic nanoparticle assembly acts as a magnetic relaxation nanoswitch allowing screening of DNA-cleaving agents J Am Chem Soc. 2002;124:2856-7 - PMID: 11902860 - DOI: 10.1021/ja017773n

E.C. Wiener, F.P. Auteri, J.W. Chen, M.W. Brechbiel, O.A. Gansow, D.J. Schneider, R.L. Belford, R.B. Clarkson, P.C. Lauterbur

Molecular Dynamics of Ion-Chelate Complexes Attached to Starburst(TM) Dendrimers J Am Chem Soc. 1996;118:7774-7782

Hilderbrand S, Lim M, Lippard S

Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. J Am Chem Soc. 2004;126:4972-8 - PMID: 15080703 - DOI: 10.1021/ja038471j

Stahl P, Kissau L, Mazitschek R, Huwe A, Furet P, Giannis A, Waldmann H

Total synthesis and biological evaluation of the nakijiquinones. J Am Chem Soc. 2001;123(47):11586-93 - PMID: 11716712 - DOI: 10.1021/ja011413i

Syeda R, Holden MA, Hwang WL, Bayley H

Screening blockers against a potassium channel with a droplet interface bilayer array. J Am Chem Soc. 2008;130(46):15543-8 - PMID: 18950170 - DOI: 10.1021/ja804968g

Hwang WL, Chen M, Cronin B, Holden MA, Bayley H

Asymmetric droplet interface bilayers. J Am Chem Soc. 2008;130(18):5878-9 - PMID: 18407631 - DOI: 10.1021/ja802089s

Hwang WL, Holden MA, White S, Bayley H

Electrical behavior of droplet interface bilayer networks: experimental analysis and modeling. J Am Chem Soc. 2007;129(38):11854-64 - PMID: 17764183 - DOI: 10.1021/ja074071a

Harisinghani MG, Weissleder R

Sensitive, noninvasive detection of lymph node metastases. PLoS Med. 2004;1(3):e66 - PMID: 15630471 - PMCID: PMC539052 - DOI: 10.1371/journal.pmed.0010066

Kelly KA, Bardeesy N, Anbazhagan R, Gurumurthy S, Berger J, Alencar H, Depinho RA, Mahmood U, Weissleder R

Targeted Nanoparticles for Imaging Incipient Pancreatic Ductal Adenocarcinoma. PLoS Med. 2008;5(4):e85 - PMID: 18416599 - PMCID: PMC2292750 - DOI: 10.1371/journal.pmed.0050085

Zhang M, Alicot EM, Chiu I, Li J, Verna N, Vorup-Jensen T, Kessler B, Shimaoka M, Chan R, Friend D, Mahmood U, Weissleder R, Moore FD, Carroll MC

Identification of the target self-antigens in reperfusion injury. J Exp Med. 2006;203(1):141-152 - PMID: 16390934 - PMCID: PMC2118091 - DOI: 10.1084/jem.20050390

Wu HJ, Sawaya H, Binstadt B, Brickelmaier M, Blasius A, Gorelik L, Mahmood U, Weissleder R, Carulli J, Benoist C, Mathis D.

Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk J Exp Med. 2007;204:1911-1922 - PMID: 17646407 - PMCID: PMC2118664 - DOI: 10.1084/jem.20070285

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The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med. 2007;204(12):3037-47 - PMID: 18025128 - PMCID: PMC2118517 - DOI: 10.1084/jem.20070885

Zippelius A, Pittet M, Batard P, Rufer N, de Smedt M, Guillaume P, Ellefsen K, Valmori D, Lienard D, Plum J, MacDonald H, Speiser D, Cerottini J, Romero P

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Ueno T, Habicht A, Clarkson MR, Albin MJ, Yamaura K, Boenisch O, Popoola J, Wang Y, Yagita H, Akiba H, Ansari MJ, Yang J, Turka LA, Rothstein DM, Padera RF, Najafian N, Sayegh MH

The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest. 2008;118(2):742-51 - PMID: 18172549 - PMCID: PMC2157561 - DOI: 10.1172/JCI32451

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Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells. J Clin Invest. 2000;106(9):1115-26 - PMID: 11067864 - PMCID: PMC301414 - DOI: 10.1172/JCI9594

Choukroun GJ, Marshansky V, Gustafson CE, McKee M, Hajjar RJ, Rosenzweig A, Brown D, Bonventre JV

Cytosolic phospholipase A(2) regulates golgi structure and modulates intracellular trafficking of membrane proteins. J Clin Invest. 2000;106(8):983-93 - PMID: 11032858 - PMCID: PMC314339 - DOI: 10.1172/JCI8914

Turvey SE, Swart E, Denis MC, Mahmood U, Benoist C, Weissleder R, Mathis D.

Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes J Clin Invest. 2005;115(9):2454-2461 - PMID: 16110329 - PMCID: PMC1187933 - DOI: 10.1172/JCI25048

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Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata J Clin Invest. 2007;117(1):195-205 - PMID: 17200719 - PMCID: PMC1716211 - DOI: 10.1172/JCI29950

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Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction. J Clin Invest. 2000;106:55-62 - PMID: 10880048 - PMCID: PMC517910 - DOI: 10.1172/JCI8768

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Neuroprotection mediated by changes in the endothelial actin cytoskeleton. J Clin Invest. 2000;106:15-24 - PMID: 10880044 - PMCID: PMC314365 - DOI: 10.1172/JCI9639

Cortez-Retamozo V, Swirski FK, Waterman P, Yuan H, Figueiredo JL, Newton AP, Upadhyay R, Vinegoni C, Kohler R, Blois J, Smith A, Nahrendorf M, Josephson L, Weissleder R, Pittet MJ

Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation J Clin Invest. 2008;118(12):4058-66 - PMID: 19033674 - PMCID: PMC2579705 - DOI: 10.1172/JCI36335

Kalabis J, Oyama K, Okawa T, Nakagawa H, Michaylira CZ, Stairs DB, Figueiredo JL, Mahmood U, Diehl JA, Herlyn M, Rustgi AK

A subpopulation of mouse esophageal basal cells has properties of stem cells with the capacity for self-renewal and lineage specification. J Clin Invest. 2008;:ePub - PMID: 19005570 - PMCID: PMC2579884

Tung CH, Weissleder R

Arginine containing peptides as delivery vectors Adv Drug Deliv Rev. 2003;55:281-94 - PMID: 12564981 - DOI: 10.1016/s0169-409x(02)00183-7

Bogdanov AA, Lewin M, Weissleder R

Approaches and agents for imaging the vascular system Adv Drug Deliv Rev. 1999;37:279-293 - PMID: 10837740 - DOI: 10.1016/s0169-409x(98)00098-2

McCarthy JR, Weissleder R

Multifunctional magnetic nanoparticles for targeted imaging and therapy. Adv Drug Deliv Rev. 2008;60:1241-1251 - PMID: 18508157 - PMCID: PMC2583936 - DOI: 10.1016/j.addr.2008.03.014

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Long-circulating iron oxides for MR imaging Adv Drug Deliv Rev. 1995;16:321-334

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Switching modes for G protein-coupled receptor activation. Nat Chem Biol. 2006;2(8):395-6 - PMID: 16850011 - DOI: 10.1038/nchembio0806-395

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Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2007;4(1):33-41 - PMID: 18026094 - PMCID: PMC2727650 - DOI: 10.1038/nchembio.2007.54

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Conformational cross-talk between alpha(2A)-adrenergic and mu-opioid receptors controls cell signaling. Nat Chem Biol. 2008;4:126-131 - PMID: 18193048 - DOI: 10.1038/nchembio.64

Denis MC, Mahmood U, Benoist C, Mathis D, Weissleder R

Imaging inflammation of the pancreatic islets in type 1 diabetes. Proc Natl Acad Sci U S A. 2004;101(34):12634-9 - PMID: 15304647 - PMCID: PMC515109 - DOI: 10.1073/pnas.0404307101

Ntziachristos V, Schellenberger EA, Ripoll J, Yessayan D, Graves E, Bogdanov A Jr, Josephson L, Weissleder R

Visualization of antitumor treatment by means of fluorescence molecular tomography with an annexin V-Cy5.5 conjugate. Proc Natl Acad Sci U S A. 2004;101(33):12294-9 - PMID: 15304657 - PMCID: PMC514472 - DOI: 10.1073/pnas.0401137101

Chen ML, Pittet MJ, Gorelik L, Flavell RA, Weissleder R, von Boehmer H, Khazaie K.

Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-{beta} signals in vivo Proc Natl Acad Sci U S A. 2005;102(2):419-24 - PMID: 15623559 - PMCID: PMC544311 - DOI: 10.1073/pnas.0408197102

Grimm J, Kirsch DG, Windsor SD, Kim CF, Santiago PM, Ntziachristos V, Jacks T, Weissleder R.

Use of gene expression profiling to direct in vivo molecular imaging of lung cancer Proc Natl Acad Sci U S A. 2005;102(40):14404-14409 - PMID: 16183744 - PMCID: PMC1242291 - DOI: 10.1073/pnas.0503920102

Zacharakis G, Kambara H, Shih H, Ripoll J, Grimm J, Saeki Y, Weissleder R, Ntziachristos V.

Volumetric tomography of fluorescent proteins through small animals in vivo Proc Natl Acad Sci U S A. 2005;102:18252-18257 - PMID: 16344470 - PMCID: PMC1317905 - DOI: 10.1073/pnas.0504628102

Bardeesy N, Aguirre AJ, Chu GC, Cheng KH, Lopez LV, Hezel AF, Feng B, Brennan C, Weissleder R, Mahmood U, Hanahan D, Redston MS, Chin L, Depinho RA

Both p16Ink4a and the p19Arf-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci U S A. 2006;103:5947-5952 - PMID: 16585505 - PMCID: PMC1458678 - DOI: 10.1073/pnas.0601273103

Swirski FK, Pittet MJ, Kircher MF, Aikawa E, Jaffer FA, Libby P, Weissleder R

Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease. Proc Natl Acad Sci U S A. 2006;103(27):10340-5 - PMID: 16801531 - PMCID: PMC1502459 - DOI: 10.1073/pnas.0604260103

Fulci G, Breymann L,Gianni D, Kurozomi K, Rhee S, Yu J, Kaur B, Louis D, Weissleder R, Caligiuri M, Chiocca A.

Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses Proc Natl Acad Sci U S A. 2006;103:12873-12878 - PMID: 16908838 - PMCID: PMC1568940 - DOI: 10.1073/pnas.0605496103

Finberg KE, Wagner CA, Bailey MA, Paunescu TG, Breton S, Brown D, Giebisch G, Geibel JP, Lifton RP

The B1-subunit of the H(+) ATPase is required for maximal urinary acidification. Proc Natl Acad Sci U S A. 2005;102(38):13616-21 - PMID: 16174750 - PMCID: PMC1224669 - DOI: 10.1073/pnas.0506769102

Pittet M, Grimm J, Berger C, Tamura T, Wojtkiewicz G, Nahrendorf M, Romero P, Swirski F, Weissleder R.

In vivo imaging of T cell delivery to tumors after adoptive transfer therapy Proc Natl Acad Sci U S A. 2007;104:12457-12461 - PMID: 17640914 - PMCID: PMC1941490 - DOI: 10.1073/pnas.0704460104

Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K

Mast cells are an essential hematopoietic component for polyp development. Proc Natl Acad Sci U S A. 2007;104:19977-82 - PMID: 18077429 - PMCID: PMC2148408 - DOI: 10.1073/pnas.0704620104

Shaw SY, Westly EC, Pittet MJ, Subramanian A, Schreiber SL, Weissleder R

Perturbational profiling of nanomaterial biologic activity. Proc Natl Acad Sci U S A. 2008;105:7387-7392 - PMID: 18492802 - PMCID: PMC2396702 - DOI: 10.1073/pnas.0802878105

Gold L, Brown D, He Y, Shtatland T, Singer B, Wu Y

From oligonucleotide shapes to genomic SELEX: novel biological regulatory loops. Proc Natl Acad Sci U S A. 1997;94:59-64 - PMID: 8990161 - PMCID: PMC19236 - DOI: 10.1073/pnas.94.1.59

Hahn C, Ross K, Warrington I, Mazitschek R, Kanegai C, Wright R, Kung A, Golub T, Stegmaier K

Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation. Proc Natl Acad Sci U S A. 2008;105(28):9751-6 - PMID: 18607002 - PMCID: PMC2474517 - DOI: 10.1073/pnas.0710413105

Shaw S, Wang J

Chirality of DNA trefoils: implications in intramolecular synapsis of distant DNA segments. Proc Natl Acad Sci U S A. 1997;94(5):1692-7 - PMID: 9050840 - PMCID: PMC19978 - DOI: 10.1073/pnas.94.5.1692

Breckwoldt M*, Chen JW*, Stangenberg L, Aikawa E, Rodriguez E, Qiu S, Moskowitz M, Weissleder R

Tracking the Inflammatory Response in Stroke in Vivo by Sensing the Enzyme Myeloperoxidase Proc Natl Acad Sci U S A. 2008;105 (47):18584-18589 - PMID: 19011099 - PMCID: PMC2587593 - DOI: 10.1073/pnas.0803945105

Niedre MJ, de Kleine RH, Aikawa E, Kirsch DG, Weissleder R, Ntziachristos V

Early photon tomography allows fluorescence detection of lung carcinomas and disease progression in mice in vivo. Proc Natl Acad Sci U S A. 2008;105(49)::19126-19131 - PMID: 19015534 - PMCID: PMC2614726 - DOI: 10.1073/pnas.0804798105

Okazaki M, Ferrandon S, Vilardaga J, Bouxsein M, Potts J, Gardella T

Prolonged signaling at the parathyroid hormone receptor by peptide ligands targeted to a specific receptor conformation. Proc Natl Acad Sci U S A. 2008;105(43):16525-30 - PMID: 18946036 - PMCID: PMC2571912 - DOI: 10.1073/pnas.0808750105

Zhu H, Acquaviva J, Ramachandran P, Boskovitz A, Woolfenden S, Bronson R, Chen J, Weissleder R, Housman D, Charest A.

Oncogenic EGFR signaling cooperates with loss of tumor suppressor gene function in gliomagenesis Proc Natl Acad Sci U S A. 0;:ePub

Evans C, Potma E, Puoris'haag M, C

Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy. Proc Natl Acad Sci U S A. 2005;102:16807-12 - PMID: 16263923 - PMCID: PMC1283840 - DOI: 10.1073/pnas.0508282102

Higgins JM, Eddington DT, Bhatia SN, Mahadevan L

Sickle cell vasoocclusion and rescue in a microfluidic device. Proc Natl Acad Sci U S A. 2007;104(51):20496-500 - PMID: 18077341 - PMCID: PMC2154459 - DOI: 10.1073/pnas.0707122105

Kelloff GJ, Krohn KA, Larson SM, Weissleder R, Mankoff DA, Hoffman JM, Link JM, Guyton KZ, Eckelman WC, Scher HI, O

The progress and promise of molecular imaging probes in oncologic drug development. Clin Cancer Res. 2005;11(22):7967-85 - PMID: 16299226 - DOI: 10.1158/1078-0432.CCR-05-1302

Ayyoub M, Zippelius A, Pittet M, Rimoldi D, Valmori D, Cerottini J, Romero P, Lejeune F, Lienard D, Speiser D

Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1. Clin Cancer Res. 2003;9:669-77 - PMID: 12576434

Pittet M, Speiser D, Lienard D, Valmori D, Guillaume P, Dutoit V, Rimoldi D, Lejeune F, Cerottini J, Romero P

Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide. Clin Cancer Res. 2001;7:796s-803s - PMID: 11300475

Girnun GD, Chen L, Silvaggi J, Drapkin R, Chirieac LR, Padera RF, Upadhyay R, Vafai SB, Weissleder R, Mahmood U, Naseri E, Buckley S, Li D, Force J, McNamara K, Demetri G, Spiegelman BM, Wong KK

Regression of drug-resistant lung cancer by the combination of rosiglitazone and Carboplatin. Clin Cancer Res. 2008;14(20):6478-86 - PMID: 18927287 - PMCID: PMC2696122 - DOI: 10.1158/1078-0432.CCR-08-1128

Bazzaro M, Lin Z, Santillan A, Lee MK, Wang MC, Chan KC, Bristow RE, Mazitschek R, Bradner J, Roden RB

Ubiquitin proteasome system stress underlies synergistic killing of ovarian cancer cells by bortezomib and a novel HDAC6 inhibitor. Clin Cancer Res. 2008;14(22):7340-7 - PMID: 19010849 - PMCID: PMC2744414 - DOI: 10.1158/1078-0432.CCR-08-0642

Ha PK, Pai SI, Westra WH, Gillison ML, Tong BC, Sidransky D, Califano JA

Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res. 2002;8(5):1203-9 - PMID: 12006539

Capone RB, Pai SI, Koch WM, Gillison ML, Danish HN, Westra WH, Daniel R, Shah KV, Sidransky D

Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma. Clin Cancer Res. 2000;6(11):4171-5 - PMID: 11106228

Shah K, Russinova E, Gadella T, Willemse J, De Vries S

The Arabidopsis kinase-associated protein phosphatase controls internalization of the somatic embryogenesis receptor kinase 1. Gene Dev. 2002;16(13):1707-20 - PMID: 12101128 - PMCID: PMC186368 - DOI: 10.1101/gad.220402

de Sousa Lopes S, Roelen B, Monteiro R, Emmens R, Lin HY, Li E, Lawson K, Mummery C

BMP signaling mediated by ALK2 in the visceral endoderm is necessary for the generation of primordial germ cells in the mouse embryo. Gene Dev. 2004;18(15):1838-49 - PMID: 15289457 - PMCID: PMC517404 - DOI: 10.1101/gad.294004

Pittet M, Mempel T

Regulation of T Cell Migration and Effector Functions-Insights from in Vivo Imaging Studies Immunol Rev. 2007;:ePub

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Regulation of T-cell migration and effector functions: insights from in vivo imaging studies. Immunol Rev. 2008;221:107-29 - PMID: 18275478 - DOI: 10.1111/j.1600-065X.2008.00584.x

Romero P, Valmori D, Pittet M, Zippelius A, Rimoldi D, Levy F, Dutoit V, Ayyoub M, Rubio-Godoy V, Michielin O, Guillaume P, Batard P, Luescher I, Lejeune F, Lienard D, Rufer N, Dietrich P, Speiser D, Cerottini J

Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma. Immunol Rev. 2002;188:81-96 - PMID: 12445283 - DOI: 10.1034/j.1600-065x.2002.18808.x

McCarthy J, Jaffer F, Weissleder R.

A Macrophage Targeted Theranostic Nanoparticle for Biomedical Applications Small. 2006;2(8-9):983-987 - PMID: 17193154 - DOI: 10.1002/smll.200600139

Sun EY, Weissleder R, Josephson L.

Continuous Analyte Sensing with Magnetic Nanoswitches Small. 2006;(2) 10:1144-1147 - PMID: 17193579 - DOI: 10.1002/smll.200600204

Perez JM, Simeone FJ, Tsourkas A, Josephson L, Weissleder R

Peroxidase substrate nanosensors for MR imaging Nano Lett. 0;4:119-122

McCarthy JR, Perez JM, Brueckner C, Weissleder R

Polymeric Nanoparticle Preparation that Eradicates Tumors. Nano Lett. 2005;5:2552-6 - PMID: 16351214 - DOI: 10.1021/nl0519229

Quinti L, Weissleder R, Tung CH

A Fluorescent Nanosensor for Apoptotic Cells Nano Lett. 2006;6 (3):488-490 - PMID: 16522048 - DOI: 10.1021/nl0524694

Lee H, Purdon AM, Chu V, Westervelt RM

Controlled Assembly of Magnetic Nanoparticles from Magnetotactic Bacteria Using Microelectromagnets Arrays Nano Lett. 0;4(5):995

Tannous BA, Kim DE, Fernandez JL, Weissleder R, Breakefield XO.

Codon-optimized gaussia luciferase cDNA for Mammalian gene expression in culture and in vivo Mol Ther. 2005;11(3):435-43 - PMID: 15727940 - DOI: 10.1016/j.ymthe.2004.10.016

Shah K, Tung CH, Breakefield X, Weissleder R.

In vivo imaging of S-TRAIL-mediated tumor regression and apoptosis Mol Ther. 2005;11 (6):926-931 - PMID: 15922963 - DOI: 10.1016/j.ymthe.2005.01.017

Lamfers ML, Fulci G, Gianni D, Tang Y, Kurozumi K, Kaur B, Moeniralm S, Saeki Y, Carette JE, Weissleder R, Vandertop WP, van Beusechem VW, Dirven CM, Chiocca EA

Cyclophosphamide Increases Transgene Expression Mediated by an Oncolytic Adenovirus in Glioma-Bearing Mice Monitored by Bioluminescence Imaging. Mol Ther. 2006;4(6):779-88 - PMID: 16996314 - PMCID: PMC2819149 - DOI: 10.1016/j.ymthe.2006.08.008

Noh KH, Kang TH, Kim JH, Pai SI, Lin KY, Hung CF, Wu TC, Kim TW

Activation of Akt as a mechanism for tumor immune evasion. Mol Ther. 2008;17(3):439-47 - PMID: 19107122 - PMCID: PMC2835083 - DOI: 10.1038/mt.2008.255

Kurozumi K, Hardcastle J, Thakur R, Yang M, Christoforidis G, Fulci G, Hochberg F, Weissleder R, Carson W, Chiocca A, Kaur B.

Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy J Natl Cancer Inst. 2007;(99) 23:1768-1781 - PMID: 18042934 - DOI: 10.1093/jnci/djm229

Marshansky V, Futai M

The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function. Curr Opin Cell Biol. 2008;20(4):415-26 - PMID: 18511251 - PMCID: PMC7111286 - DOI: 10.1016/j.ceb.2008.03.015

Shah K, Bureau E, Kim DE, Yang K, Tang Y, Weissleder R, Breakefield XO.

Glioma therapy and real-time imaging of neural precursor cell migration and tumor regression Ann Neurol. 2005;57(1):34-41 - PMID: 15622535 - DOI: 10.1002/ana.20306

Johnson J, Wiley R, Fattouh R, Swirski F, Gajewska B, Coyle A, Gutierrez-Ramos J, Ellis R, Inman M, Jordana M

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling. Am J Resp Crit Care. 2004;169(3):378-85 - PMID: 14597485 - DOI: 10.1164/rccm.200308-1094OC

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Fluorescence Molecular Imaging. Annu Rev Biomed Eng. 2006;8:1-33 - PMID: 16834550 - DOI: 10.1146/annurev.bioeng.8.061505.095831

Nahrendorf M, Spindler M, Hu K, Bauer L, Ritter O, Nordbeck P, Quaschning T, Hiller K, Wallis J, Ertl G, Bauer W, Neubauer S

Creatine kinase knockout mice show left ventricular hypertrophy and dilatation, but unaltered remodeling post-myocardial infarction. Cardiovasc Res. 2005;65(2):419-27 - PMID: 15639481 - DOI: 10.1016/j.cardiores.2004.10.006

Nahrendorf M, Frantz S, Hu K, von zur Mahlen C, Tomaszewski M, Scheuermann H, Kaiser R, Jazbutyte V, Beer S, Bauer W, Neubauer S, Ertl G, Allolio B, Callies F

Effect of testosterone on post-myocardial infarction remodeling and function. Cardiovasc Res. 2003;57(2):370-8 - PMID: 12566109 - DOI: 10.1016/s0008-6363(02)00701-0

Pelzer T, Jazbutyte V, Hu K, Segerer S, Nahrendorf M, Nordbeck P, Bonz AW, Muck J, Fritzemeier KH, Hegele-Hartung C, Ertl G, Neyses L

The estrogen receptor-alpha agonist 16alpha-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats. Cardiovasc Res. 2005;67(4):604-12 - PMID: 15950203 - DOI: 10.1016/j.cardiores.2005.04.035

Hu K, Gaudron P, Anders HJ, Weidemann F, Turschner O, Nahrendorf M, Ertl G

Chronic effects of early started angiotensin converting enzyme inhibition and angiotensin AT1-receptor subtype blockade in rats with myocardial infarction: role of bradykinin. Cardiovasc Res. 1998;39(2):401-12 - PMID: 9798525 - DOI: 10.1016/s0008-6363(98)00090-x

Zaharchuk G, Mandeville JB, Bogdanov AA Jr, Weissleder R, Rosen BR, Marota JJ

Cerebrovascular dynamics of autoregulation and hypoperfusion. An MRI study of CBF and changes in total and microvascular cerebral blood volume during hemorrhagic hypotension Stroke. 1999;30:2197-204; discussion 2204-5 - PMID: 10512929 - DOI: 10.1161/01.str.30.10.2197

Kim DE, Schellingerhout D, Ishii K, Shah K, Weissleder R

Imaging of Stem Cell Recruitment to Ischemic Infarcts in a Murine Model Stroke. 2004;35:952-7 - PMID: 14988578 - DOI: 10.1161/01.STR.0000120308.21946.5D

Touhami M, Fauvel-Lafève F, Da Silva N, Chomienne C, Legrand C

Induction of thrombospondin-1 by all-trans retinoic acid modulates growth and differentiation of HL-60 myeloid leukemia cells. Leukemia. 1997;11(12):2137-42 - PMID: 9447832 - DOI: 10.1038/sj.leu.2400866

Gruss HJ, DaSilva N, Hu ZB, Uphoff CC, Goodwin RG, Drexler HG

Expression and regulation of CD30 ligand and CD30 in human leukemia-lymphoma cell lines. Leukemia. 1994;8(12):2083-94 - PMID: 7528856

DaSilva N, Hu ZB, Ma W, Rosnet O, Birnbaum D, Drexler HG

Expression of the FLT3 gene in human leukemia-lymphoma cell lines. Leukemia. 1994;8(5):885-8 - PMID: 8182945

Naxerova K, Bult CJ, Peaston A, Fancher K, Knowles BB, Kasif S, Kohane IS

Analysis of gene expression in a developmental context emphasizes distinct biological leitmotifs in human cancers. Genome Biol. 2008;9(7):R108 - PMID: 18611264 - PMCID: PMC2530866 - DOI: 10.1186/gb-2008-9-7-r108

Chen JW, Breckwoldt MO, Aikawa E, Chiang G, Weissleder R

Myeloperoxidase-targeted imaging of active inflammatory lesions in murine experimental autoimmune encephalomyelitis. Brain. 2008;131(Pt 4):1123-33 - PMID: 18234693 - PMCID: PMC4044727 - DOI: 10.1093/brain/awn004

Bogdanov A, Weissleder R

The development of in vivo imaging systems to study gene expression. Trends Biotechnol. 1998;16(1):5-10 - PMID: 9470227 - DOI: 10.1016/S0167-7799(97)01150-5

Zhao M, Weissleder R

Intracellular cargo delivery using tat peptide and derivatives Med Res Rev. 2004;24:1-12 - PMID: 14595670 - DOI: 10.1002/med.10056

Pittet M, Zippelius A, Valmori D, Speiser D, Cerottini J, Romero P

Melan-A/MART-1-specific CD8 T cells: from thymus to tumor. Trends Immunol. 2002;23:325-8 - PMID: 12103339 - DOI: 10.1016/s1471-4906(02)02244-5

Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bunemann M

Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends Pharmacol Sci. 2008;29(3):159-65 - PMID: 18262662 - DOI: 10.1016/j.tips.2007.12.002

Bogdanov AA, Callahan RJ, Wilkinson RA, Martin C, Cameron JA, Fischman AJ, Brady TJ, Weissleder R

Synthetic copolymer kit for radionuclide blood-pool imaging. J Nucl Med. 1994;35(11):1880-6 - PMID: 7965173

Izawa A*, Ueno T*, Jurewicz M, Ito T, Tanaka K, Takahashi M, Ikeda U, Sobolev O, Fiorina P, Smith RN, Hynes RO, Abdi R

Importance of donor- and recipient-derived selectins in cardiac allograft rejection. J Am Soc Nephrol. 2007;18(11):2929-36 - PMID: 17928506 - DOI: 10.1681/ASN.2006111261

Breton S, Marsolais M, Lapointe JY, Laprade R

Cell volume increases of physiologic amplitude activate basolateral K and CI conductances in the rabbit proximal convoluted tubule. J Am Soc Nephrol. 1996;7(10):2072-87 - PMID: 8915967 - DOI: 10.1681/ASN.V7102072

Breton S, Brown D

Cold-induced microtubule disruption and relocalization of membrane proteins in kidney epithelial cells. J Am Soc Nephrol. 1998;9(2):155-66 - PMID: 9527391 - DOI: 10.1681/ASN.V92155

Sabolić I, Herak-Kramberger CM, Breton S, Brown D

Na/K-ATPase in intercalated cells along the rat nephron revealed by antigen retrieval. J Am Soc Nephrol. 1999;10(5):913-22 - PMID: 10232676 - DOI: 10.1681/ASN.V105913

Vallet M, Picard N, Loffing-Cueni D, Fysekidis M, Bloch-Faure M, Desch

Pendrin regulation in mouse kidney primarily is chloride-dependent. J Am Soc Nephrol. 2006;17(8):2153-63 - PMID: 16825334 - DOI: 10.1681/ASN.2005101054

Russo LM, Sandoval RM, Campos SB, Molitoris BA, Comper WD, Brown D

Impaired Tubular Uptake Explains Albuminuria in Early Diabetic Nephropathy. J Am Soc Nephrol. 2008;20(3):489-94 - PMID: 19118149 - PMCID: PMC2653682 - DOI: 10.1681/ASN.2008050503

Choy E, Yelensky R, Bonakdar S, Plenge RM, Saxena R, De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C, Rivas M, Dermitzakis ET, Cahir-McFarland E, Kieff E, Hafler D, Daly MJ, Altshuler D

Genetic Analysis of Human Traits In Vitro: Drug Response and Gene Expression in Lymphoblastoid Cell Lines PLoS Genet. 2008;4(11):e1000287 - PMID: 19043577 - PMCID: PMC2583954 - DOI: 10.1371/journal.pgen.1000287

Ku M, Koche R, Rheinbay E, Mendenhall E, Endoh M, Mikkelsen T, Presser A, Nusbaum C, Xie X, Chi A, Adli M, Kasif S, Ptaszek L, Cowan C, Lander E, Koseki H, Bernstein B

Genomewide analysis of PRC1 and PRC2 occupancy identifies two classes of bivalent domains. PLoS Genet. 2008;4(10):e1000242 - PMID: 18974828 - PMCID: PMC2567431 - DOI: 10.1371/journal.pgen.1000242

Shtatland T, Gill S, Javornik B, Johansson H, Singer B, Uhlenbeck O, Zichi D, Gold L

Interactions of Escherichia coli RNA with bacteriophage MS2 coat protein: genomic SELEX. Nucleic Acids Res. 2000;28:E93 - PMID: 11058143 - PMCID: PMC113162 - DOI: 10.1093/nar/28.21.e93

Singer B, Shtatland T, Brown D, Gold L

Libraries for genomic SELEX. Nucleic Acids Res. 1997;25:781-6 - PMID: 9016629 - PMCID: PMC146522 - DOI: 10.1093/nar/25.4.781

Abrams E, Shtatland T, Lerman L

PCR assay for a polymorphic TaqI site in the human K-ras-2 gene on chromosome 12p (KRAS2). Nucleic Acids Res. 1991;19:4795 - PMID: 1679926 - PMCID: PMC328755 - DOI: 10.1093/nar/19.17.4795

Pittet M, Swirski F, Reynolds F, Josephson L, Weissleder R.

Labeling of immune cells for in vivo imaging using magnetofluorescent nanoparticles Nat Protoc. 2006;1(1):73-79 - PMID: 17406214 - DOI: 10.1038/nprot.2006.11

Bremer C, Mustafa M, Bogdanov A Jr, Ntziachristos V, Petrovsky A, Weissleder R

Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice Radiology. 2003;226:214-20 - PMID: 12511693 - DOI: 10.1148/radiol.2261012140

Mahmood U, Tung CH, Tang Y, Weissleder R

Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice Radiology. 2002;224:446-51 - PMID: 12147841 - DOI: 10.1148/radiol.2242011589

Bremer C, Tung CH, Bogdanov A Jr, Weissleder R

Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes Radiology. 2002;222:814-8 - PMID: 11867806 - DOI: 10.1148/radiol.2223010812

Weissleder R, Mahmood U

Molecular imaging Radiology. 2001;219:316-33 - PMID: 11323453 - DOI: 10.1148/radiology.219.2.r01ma19316

Moore A, Josephson L, Bhorade RM, Basilion JP, Weissleder R

Human transferrin receptor gene as a marker gene for MR imaging Radiology. 2001;221:244-50 - PMID: 11568347 - DOI: 10.1148/radiol.2211001784

Bremer C, Bredow S, Mahmood U, Weissleder R, Tung CH

Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model Radiology. 2001;221:523-9 - PMID: 11687699 - DOI: 10.1148/radiol.2212010368

Moore A, Marecos E, Bogdanov A Jr, Weissleder R

Tumoral distribution of long-circulating dextran-coated iron oxide nanoparticles in a rodent model Radiology. 2000;214:568-74 - PMID: 10671613 - DOI: 10.1148/radiology.214.2.r00fe19568

Weissleder R

Molecular imaging: exploring the next frontier Radiology. 1999;212:609-14 - PMID: 10478223 - DOI: 10.1148/radiology.212.3.r99se18609

Mahmood U, Tung CH, Bogdanov A Jr, Weissleder R

Near-infrared optical imaging of protease activity for tumor detection Radiology. 1999;213:866-70 - PMID: 10580968 - DOI: 10.1148/radiology.213.3.r99dc14866

Funovics MA, Weissleder R, Mahmood U

Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice. Radiology. 2004;231(3):659-66 - PMID: 15163807 - DOI: 10.1148/radiol.2313030831

Mahmood U

Can MR Imaging Be Used to Track Delivery of Intravascularly Administered Stem Cells? Radiology. 2004;233(3):625-6 - PMID: 15564396 - DOI: 10.1148/radiol.2333041190

Chen JW, Querol Sans M, Bogdanov Jr A, Weissleder R

Imaging of myeloperoxidase in mice by using novel amplifiable paramagnetic substrates Radiology. 2006;240 (2):473-81 - PMID: 16864673 - DOI: 10.1148/radiol.2402050994

Mahmood U

Can a clinically used chemoembolization vehicle improve transgene delivery? Radiology. 2006;240(3):619-20 - PMID: 16926318 - DOI: 10.1148/radiol.2403060761

Kim DE, Tsuji K, Kim YR, Mueller FJ, Eom HS, Snyder EY, Lo EH, Weissleder R, Schellingerhout D

Neural Stem Cell Transplant Survival in Brains of Mice: Assessing the Effect of Immunity and Ischemia by using Real-time Bioluminescent Imaging. Radiology. 2006;241(3):822-830 - PMID: 17114629 - DOI: 10.1148/radiol.2413050466

Montet X, Figueiredo JL, Alencar H, Ntziachristos V, Mahmood U, Weissleder R.

Tomographic fluorescence imaging of tumor vascular volume in mice. Radiology. 2007;242 (3):751-758 - PMID: 17325064 - DOI: 10.1148/radiol.2423052065

Alencar H, Funovics MA, Figueiredo J, Sawaya H, Weissleder R, Mahmood U

Colonic Adenocarcinomas: Near-Infrared Microcatheter Imaging of Smart Probes for Early Detection. Radiology. 2007;244(1):232-8 - PMID: 17507718 - DOI: 10.1148/radiol.2441052114

Upadhyay R, Sheth RA, Weissleder R, Mahmood U

Quantitative Real-time Catheter-based Fluorescence Molecular Imaging in Mice. Radiology. 2007;245(2):523-31 - PMID: 17940307 - DOI: 10.1148/radiol.2452061613

Nahrendorf M, Hiller K, Theisen D, Hu K, Waller C, Kaiser R, Haase A, Ertl G, Brinkmann R, Bauer W

Effect of transmyocardial laser revascularization on myocardial perfusion and left ventricular remodeling after myocardial infarction in rats. Radiology. 2002;225(2):487-93 - PMID: 12409584 - DOI: 10.1148/radiol.2252011325

Goldberg M, Gazelle G, Boland G, Hahn P, Mayo-Smith W, Pivovarov M, Halpern E, Wittenberg J

Focal hepatic lesions: effect of three-dimensional wavelet compression on detection at CT. Radiology. 1997;202:159-65 - PMID: 8988206 - DOI: 10.1148/radiology.202.1.8988206

Gee MS, Upadhyay R, Bergquist H, Alencar H, Reynolds F, Maricevich M, Weissleder R, Josephson L, Mahmood U

Human Breast Cancer Tumor Models: Molecular Imaging of Drug Susceptibility and Dosing during HER2/neu-targeted Therapy. Radiology. 2008;248(3):925-35 - PMID: 18647846 - PMCID: PMC2798096 - DOI: 10.1148/radiol.2482071496

Korosoglou G, Shah S, Vonken EJ, Gilson WD, Schar M, Tang L, Kraitchman DL, Boston RC, Sosnovik DE, Weiss RG, Weissleder R, Stuber M

Off-Resonance Angiography: A New Method to Depict Vessels--Phantom and Rabbit Studies. Radiology. 2008;249(2)::501-509 - PMID: 18780823 - PMCID: PMC2657865 - DOI: 10.1148/radiol.2491071706

de Marco G, Bogdanov A, Marecos E, Moore A, Simonova M, Weissleder R

MR imaging of gene delivery to the central nervous system with an artificial vector. Radiology. 1998;208(1):65-71 - PMID: 9646794 - DOI: 10.1148/radiology.208.1.9646794

Weissleder R, Simonova M, Bogdanova A, Bredow S, Enochs WS, Bogdanov A

MR imaging and scintigraphy of gene expression through melanin induction. Radiology. 1997;204(2):425-9 - PMID: 9240530 - DOI: 10.1148/radiology.204.2.9240530

Enochs WS, Petherick P, Bogdanova A, Mohr U, Weissleder R

Paramagnetic metal scavenging by melanin: MR imaging. Radiology. 1997;204(2):417-23 - PMID: 9240529 - DOI: 10.1148/radiology.204.2.9240529

Harisinghani MG, Saini S, Weissleder R, Halpern EF, Schima W, Rubin DL, Stillman AE, Sica GT, Small WC, Hahn PF

Differentiation of liver hemangiomas from metastases and hepatocellular carcinoma at MR imaging enhanced with blood-pool contrast agent Code-7227. Radiology. 1997;202(3):687-91 - PMID: 9051017 - DOI: 10.1148/radiology.202.3.9051017

Harika L, Weissleder R, Poss K, Papisov MI

Macromolecular intravenous contrast agent for MR lymphography: characterization and efficacy studies. Radiology. 1996;198(2):365-70 - PMID: 8596833 - DOI: 10.1148/radiology.198.2.8596833

Gupta H, Wilkinson RA, Bogdanov AA, Callahan RJ, Weissleder R

Inflammation: imaging with methoxy poly(ethylene glycol)-poly-L-lysine-DTPA, a long-circulating graft copolymer. Radiology. 1995;197(3):665-9 - PMID: 7480736 - DOI: 10.1148/radiology.197.3.7480736

Zimmer C, Weissleder R, Poss K, Bogdanova A, Wright SC, Enochs WS

MR imaging of phagocytosis in experimental gliomas. Radiology. 1995;197(2):533-8 - PMID: 7480707 - DOI: 10.1148/radiology.197.2.7480707

Zimmer C, Weissleder R, O'Connor D, LaPointe L, Brady TJ, Enochs WS

Cerebral iron oxide distribution: in vivo mapping with MR imaging. Radiology. 1995;196(2):521-7 - PMID: 7617871 - DOI: 10.1148/radiology.196.2.7617871

Gupta H, Weissleder R, Bogdanov AA, Brady TJ

Experimental gastrointestinal hemorrhage: detection with contrast-enhanced MR imaging and scintigraphy. Radiology. 1995;196(1):239-44 - PMID: 7784574 - DOI: 10.1148/radiology.196.1.7784574

Weissleder R

Liver MR imaging with iron oxides: toward consensus and clinical practice. Radiology. 1994;193(3):593-5 - PMID: 7972790 - DOI: 10.1148/radiology.193.3.7972790

Reimer P, Weissleder R, Shen T, Knoefel WT, Brady TJ

Pancreatic receptors: initial feasibility studies with a targeted contrast agent for MR imaging. Radiology. 1994;193(2):527-31 - PMID: 7972773 - DOI: 10.1148/radiology.193.2.7972773

van Everdingen KJ, Enochs WS, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R

Determinants of in vivo MR imaging of slow axonal transport. Radiology. 1994;193(2):485-91 - PMID: 7526413 - DOI: 10.1148/radiology.193.2.7526413

Weissleder R, Heautot JF, Schaffer BK, Nossiff N, Papisov MI, Bogdanov A, Brady TJ

MR lymphography: study of a high-efficiency lymphotrophic agent. Radiology. 1994;191(1):225-30 - PMID: 8134576 - DOI: 10.1148/radiology.191.1.8134576

Bogdanov AA, Weissleder R, Frank HW, Bogdanova AV, Nossif N, Schaffer BK, Tsai E, Papisov MI, Brady TJ

A new macromolecule as a contrast agent for MR angiography: preparation, properties, and animal studies. Radiology. 1993;187(3):701-6 - PMID: 8497616 - DOI: 10.1148/radiology.187.3.8497616

Reimer P, Weissleder R, Wittenberg J, Brady TJ

Receptor-directed contrast agents for MR imaging: preclinical evaluation with affinity assays. Radiology. 1992;182(2):565-9 - PMID: 1732982 - DOI: 10.1148/radiology.182.2.1732982

Weissleder R, Lee AS, Khaw BA, Shen T, Brady TJ

Antimyosin-labeled monocrystalline iron oxide allows detection of myocardial infarct: MR antibody imaging. Radiology. 1992;182(2):381-5 - PMID: 1732953 - DOI: 10.1148/radiology.182.2.1732953

Weissleder R, Lee AS, Fischman AJ, Reimer P, Shen T, Wilkinson R, Callahan RJ, Brady TJ

Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging. Radiology. 1991;181(1):245-9 - PMID: 1887040 - DOI: 10.1148/radiology.181.1.1887040

Reimer P, Weissleder R, Brady TJ, Yeager AE, Baldwin BH, Tennant BC, Wittenberg J

Experimental hepatocellular carcinoma: MR receptor imaging. Radiology. 1991;180(3):641-5 - PMID: 1871273 - DOI: 10.1148/radiology.180.3.1871273

Seneterre E, Weissleder R, Jaramillo D, Reimer P, Lee AS, Brady TJ, Wittenberg J

Bone marrow: ultrasmall superparamagnetic iron oxide for MR imaging. Radiology. 1991;179(2):529-33 - PMID: 2014305 - DOI: 10.1148/radiology.179.2.2014305

Reimer P, Weissleder R, Lee AS, Buettner S, Wittenberg J, Brady TJ

Asialoglycoprotein receptor function in benign liver disease: evaluation with MR imaging. Radiology. 1991;178(3):769-74 - PMID: 1994416 - DOI: 10.1148/radiology.178.3.1994416

Lee AS, Weissleder R, Brady TJ, Wittenberg J

Lymph nodes: microstructural anatomy at MR imaging. Radiology. 1991;178(2):519-22 - PMID: 1987619 - DOI: 10.1148/radiology.178.2.1987619

Reimer P, Weissleder R, Lee AS, Wittenberg J, Brady TJ

Receptor imaging: application to MR imaging of liver cancer. Radiology. 1990;177(3):729-34 - PMID: 2243978 - DOI: 10.1148/radiology.177.3.2243978

Hahn PF, Stark DD, Lewis JM, Saini S, Elizondo G, Weissleder R, Fretz CJ, Ferrucci JT

First clinical trial of a new superparamagnetic iron oxide for use as an oral gastrointestinal contrast agent in MR imaging. Radiology. 1990;175(3):695-700 - PMID: 2343116 - DOI: 10.1148/radiology.175.3.2343116

Weissleder R, Elizondo G, Wittenberg J, Lee AS, Josephson L, Brady TJ

Ultrasmall superparamagnetic iron oxide: an intravenous contrast agent for assessing lymph nodes with MR imaging. Radiology. 1990;175(2):494-8 - PMID: 2326475 - DOI: 10.1148/radiology.175.2.2326475

Weissleder R, Elizondo G, Wittenberg J, Rabito CA, Bengele HH, Josephson L

Ultrasmall superparamagnetic iron oxide: characterization of a new class of contrast agents for MR imaging. Radiology. 1990;175(2):489-93 - PMID: 2326474 - DOI: 10.1148/radiology.175.2.2326474

Elizondo G, Weissleder R, Stark DD, Guerra J, Garza J, Fretz CJ, Todd LE, Ferrucci JT

Hepatic cirrhosis and hepatitis: MR imaging enhanced with superparamagnetic iron oxide. Radiology. 1990;174(3 Pt 1):797-801 - PMID: 2305063 - DOI: 10.1148/radiology.174.3.2305063

Hahn PF, Stark DD, Weissleder R, Elizondo G, Saini S, Ferrucci JT

Clinical application of superparamagnetic iron oxide to MR imaging of tissue perfusion in vascular liver tumors. Radiology. 1990;174(2):361-6 - PMID: 2296646 - DOI: 10.1148/radiology.174.2.2296646

Fretz CJ, Elizondo G, Weissleder R, Hahn PF, Stark DD, Ferrucci JT

Superparamagnetic iron oxide-enhanced MR imaging: pulse sequence optimization for detection of liver cancer. Radiology. 1989;172(2):393-7 - PMID: 2748820 - DOI: 10.1148/radiology.172.2.2748820

Weissleder R, Thrall JH

The lymphatic system: diagnostic imaging studies. Radiology. 1989;172(2):315-7 - PMID: 2748809 - DOI: 10.1148/radiology.172.2.2748809

Weissleder R, Elizondo G, Josephson L, Compton CC, Fretz CJ, Stark DD, Ferrucci JT

Experimental lymph node metastases: enhanced detection with MR lymphography. Radiology. 1989;171(3):835-9 - PMID: 2717761 - DOI: 10.1148/radiology.171.3.2717761

Dousset M, Weissleder R, Hendrick RE, Stark DD, Fretz CJ, Elizondo G, Hahn PF, Saini S, Ferrucci JT

Short TI inversion-recovery imaging of the liver: pulse-sequence optimization and comparison with spin-echo imaging. Radiology. 1989;171(2):327-33 - PMID: 2704797 - DOI: 10.1148/radiology.171.2.2704797

Rummeny E, Weissleder R, Sironi S, Stark DD, Comptom CC, Hahn PF, Saini S, Wittenberg J, Ferrucci JT

Central scars in primary liver tumors: MR features, specificity, and pathologic correlation. Radiology. 1989;171(2):323-6 - PMID: 2539605 - DOI: 10.1148/radiology.171.2.2539605

Weissleder H, Weissleder R

Interstitial lymphangiography: initial clinical experience with a dimeric nonionic contrast agent. Radiology. 1989;170(2):371-4 - PMID: 2911660 - DOI: 10.1148/radiology.170.2.2911660

Weissleder R, Hahn PF, Stark DD, Elizondo G, Saini S, Todd LE, Wittenberg J, Ferrucci JT

Superparamagnetic iron oxide: enhanced detection of focal splenic tumors with MR imaging. Radiology. 1988;169(2):399-403 - PMID: 3174987 - DOI: 10.1148/radiology.169.2.3174987

Stark DD, Weissleder R, Elizondo G, Hahn PF, Saini S, Todd LE, Wittenberg J, Ferrucci JT

Superparamagnetic iron oxide: clinical application as a contrast agent for MR imaging of the liver. Radiology. 1988;168(2):297-301 - PMID: 3393649 - DOI: 10.1148/radiology.168.2.3393649

Weissleder H, Weissleder R

Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology. 1988;167(3):729-35 - PMID: 3363131 - DOI: 10.1148/radiology.167.3.3363131

Tsang YM, Stark DD, Chen MC, Weissleder R, Wittenberg J, Ferrucci JT

Hepatic micrometastases in the rat: ferrite-enhanced MR imaging. Radiology. 1988;167(1):21-4 - PMID: 3347724 - DOI: 10.1148/radiology.167.1.3347724

Weissleder R, Stark DD, Rummeny EJ, Compton CC, Ferrucci JT

Splenic lymphoma: ferrite-enhanced MR imaging in rats. Radiology. 1988;166(2):423-30 - PMID: 3336717 - DOI: 10.1148/radiology.166.2.3336717

Elizondo G, Weissleder R, Stark DD, Todd LE, Compton C, Wittenberg J, Ferrucci JT

Amebic liver abscess: diagnosis and treatment evaluation with MR imaging. Radiology. 1987;165(3):795-800 - PMID: 2891154 - DOI: 10.1148/radiology.165.3.2891154

Waller C, Kahler E, Hiller KH, Hu K, Nahrendorf M, Voll S, Haase A, Ertl G, Bauer WR

Myocardial perfusion and intracapillary blood volume in rats at rest and with coronary dilatation: MR imaging in vivo with use of a spin-labeling technique. Radiology. 2000;215(1):189-97 - PMID: 10751486 - DOI: 10.1148/radiology.215.1.r00ap07189

Brown D, Breton S

Sorting proteins to their target membranes. Kidney Int. 2000;57(3):816-24 - PMID: 10720934 - DOI: 10.1046/j.1523-1755.2000.00920.x

Russo LM, Sandoval RM, McKee M, Osicka TM, Collins AB, Brown D, Molitoris BA, Comper WD

The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: retrieval is disrupted in nephrotic states. Kidney Int. 2007;71(6):504-13 - PMID: 17228368 - DOI: 10.1038/sj.ki.5002041

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Controversies in nephrology: Response to ''renal albumin handling, facts, and artifacts'' Kidney Int. 2007;72(10):1195-7 - PMID: 17851467 - DOI: 10.1038/sj.ki.5002528

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Response to ''Albumin concentration in the Bowman's capsule: Multiphoton microscopy vs micropuncture technique'' Kidney Int. 2007;72:1411 - PMID: 18004315

Russo LM, Sandoval RM, Brown D, Molitoris BA, Comper WD

Response to ''On the origin of albuminuria'' Kidney Int. 2007;72:1409-10 - PMID: 18004312

Gutierrez O, Lin H

Refractory hyponatremia. Kidney Int. 2007;71(1):79-82 - PMID: 16985516 - DOI: 10.1038/sj.ki.5001845

Zalyapin EA, Bouley R, Hasler U, Vilardaga JP, Lin HY, Brown D, Ausiello DA

Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling. Kidney Int. 2008;74(12):1557-67 - PMID: 18813286 - PMCID: PMC3730289 - DOI: 10.1038/ki.2008.412

Miller RL, Lucero OM, Riemondy KA, Baumgartner BK, Brown D, Breton S, Nelson RD

The V-ATPase B1-subunit promoter drives expression of Cre recombinase in intercalated cells of the kidney. Kidney Int. 2008;75(4):435-9 - PMID: 19052537 - PMCID: PMC4301582 - DOI: 10.1038/ki.2008.569

Moore A, Bonner-Weir S, Weissleder R

Noninvasive in vivo measurement of beta-cell mass in mouse model of diabetes Diabetes. 2001;50:2231-6 - PMID: 11574403 - DOI: 10.2337/diabetes.50.10.2231

Russo LM, del Re E, Brown D, Lin HY

Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor. Diabetes. 2007;56(2):380-8 - PMID: 17259382 - DOI: 10.2337/db06-1018

Cruz DN, Perazella MA, Bellomo R, de Cal M, Polanco N, Corradi V, Lentini P, Nalesso F, Ueno T, Ranieri VM, Ronco C

Effectiveness of polymyxin B-immobilized fiber column in sepsis: a systematic review. Crit Care. 2008;11(2):R47 - PMID: 17448226 - PMCID: PMC2206475 - DOI: 10.1186/cc5780

Hewett J, Nery F, Niland B, Ge P, Tan P, Hadwiger P, Tannous B, Sah D, Breakefield X

siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells. Hum Mol Genet. 2008;17:1436-45 - PMID: 18258738 - PMCID: PMC2861568 - DOI: 10.1093/hmg/ddn032

McCarthy J, Kelly KA, Sun EY, Weissleder R.

Targeted delivery of multifunctional magnetic nanoparticles Nanomedicine. 2007;2(2):153-167 - PMID: 17716118 - DOI: 10.2217/17435889.2.2.153

Engelmayr G, Rabkin E, Sutherland F, Schoen F, Mayer J, Sacks M

The independent role of cyclic flexure in the early in vitro development of an engineered heart valve tissue. Biomaterials . 2005;26:175-87 - PMID: 15207464 - DOI: 10.1016/j.biomaterials.2004.02.035

Sosnovik DE, Weissleder R

Emerging concepts in molecular MRI. Curr Opin Biotech. 2007;18(1):4-10 - PMID: 17126545 - DOI: 10.1016/j.copbio.2006.11.001

Wunder A, Tung CH, Muller-Ladner U, Weissleder R, Mahmood U

In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response. Arth Rheum/AR C Res. 2004;50(8):2459-65 - PMID: 15334458 - DOI: 10.1002/art.20379

Izmailova ES, Paz N, Alencar H, Chun M, Schopf L, Hepperle M, Lane JH, Harriman G, Xu Y, Ocain T, Weissleder R, Mahmood U, Healy AM, Jaffee B

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. Arth Rheum/AR C Res. 2007;56(1):117-128 - PMID: 17195214 - DOI: 10.1002/art.22303

Mendenhall E, Bernstein B

Chromatin state maps: new technologies, new insights. Curr Opin Genet Dev. 2008;18(2):109-15 - PMID: 18339538 - PMCID: PMC2486450 - DOI: 10.1016/j.gde.2008.01.010

Khazaie K, von Boehmer H

The impact of CD4(+)CD25(+) Treg on tumor specific CD8(+) T cell cytotoxicity and cancer. Semin Cancer Biol. 2006;16(2):124-136 - PMID: 16443370 - DOI: 10.1016/j.semcancer.2005.11.006

Speiser D, Pittet M, Rimoldi D, Guillaume P, Luescher I, Lienard D, Lejeune F, Cerottini J, Romero P

Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells. Semin Cancer Biol. 2003;13:461-72 - PMID: 15001165 - DOI: 10.1016/j.semcancer.2003.09.010

Shah K, Tang Y, Breakefield X, Weissleder R

Real-time imaging of TRAIL-induced apoptosis of glioma tumors in vivo Oncogene. 2003;22:6865-72 - PMID: 14534533 - DOI: 10.1038/sj.onc.1206748

Trink B, Pai SI, Spunt SL, Raman V, Cairns P, Jen J, Gabrielson E, Sukumar S, Sidransky D

Absence of TSG101 transcript abnormalities in human cancers. Oncogene. 1998;16(21):2815-8 - PMID: 9652749 - DOI: 10.1038/sj.onc.1201795

Shih HA, Harisinghani M, Zietman AL, Wolfgang JA, Saksena M, Weissleder R.

Mapping of nodal disease in locally advanced prostate cancer: Rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy Int J Radiat Oncol Biol Phys. 2005;63(4):1262-9 - PMID: 16253781 - DOI: 10.1016/j.ijrobp.2005.07.952

Basilion JP, Yeon S, Botnar R

Magnetic Resonance Imaging: Utility as a Molecular Imaging Modality. Curr Top Dev Biol. 2005;70(c):1-33 - PMID: 16338335 - DOI: 10.1016/S0070-2153(05)70001-6

Mahmood U, Josephson L

Molecular MR Imaging Probes P IEEE. 0;93 (4):800-808

Shah K, Hingtgen S, Kasmieh R, Figueiredo JL, Garcia-Garcia E, Martinez-Serrano A, Breakefield X, Weissleder R

Bimodal viral vectors and in vivo imaging reveal the fate of human neural stem cells in experimental glioma model. J Neurosci. 2008;28:4406-13 - PMID: 18434519 - PMCID: PMC3021321 - DOI: 10.1523/JNEUROSCI.0296-08.2008

Samad T, Srinivasan A, Karchewski L, Jeong S, Campagna J, Ji R, Fabrizio D, Zhang Y, Lin HY, Bell E, Woolf C

DRAGON: a member of the repulsive guidance molecule-related family of neuronal- and muscle-expressed membrane proteins is regulated by DRG11 and has neuronal adhesive properties. J Neurosci. 2004;24(8):2027-36 - PMID: 14985445 - PMCID: PMC6730385 - DOI: 10.1523/JNEUROSCI.4115-03.2004

Lee H, Liu Y, Ham D, Westervelt RM

Integrated cell manipulation system--CMOS/microfluidic hybrid. Lab Chip. 2007;7(3):331-7 - PMID: 17330164 - DOI: 10.1039/b700373k

Lindquist NC, Lesuffleur A, Im H, Oh SH

Sub-micron resolution surface plasmon resonance imaging enabled by nanohole arrays with surrounding Bragg mirrors for enhanced sensitivity and isolation. Lab Chip. 2008;9(3):382-7 - PMID: 19156286 - DOI: 10.1039/b816735d

Tsourkas A, Newton G, Perez JM, Basilion J, Weissleder R.

Detection of Peroxidase-Mediated Dityrosine Formation with Enhanced Yellow Fluorescent Protein Anal Chem. 2005;77:2862-2867 - PMID: 15859603 - DOI: 10.1021/ac0480747

Taktak S, Sosnovik D, Cima MJ, Weissleder R, Josephson L

Multiparameter Magnetic Relaxation Switch Assays. Anal Chem. 2007;(79) 23:8863-9 - PMID: 17983206 - DOI: 10.1021/ac701976p

Jaffer FA, Tung CH, Gerszten RE, Weissleder R

In vivo imaging of thrombin activity in experimental thrombi with thrombin-sensitive near-infrared molecular probe Arterioscler Thromb Vasc Biol. 2002;22:1929-35 - PMID: 12426227 - DOI: 10.1161/01.atv.0000033089.56970.2d

Simoncini T, Rabkin E, Liao J

Molecular basis of cell membrane estrogen receptor interaction with phosphatidylinositol 3-kinase in endothelial cells. Arterioscler Thromb Vasc Biol. 2003;23:198-203 - PMID: 12588759 - DOI: 10.1161/01.atv.0000053846.71621.93

Querol M, Chen JW, Weissleder R, Bogdanov A Jr.

DTPA-bisamide-Based MR Sensor Agents for Peroxidase Imaging Org Lett. 2005;7(9):1719-22 - PMID: 15844889 - DOI: 10.1021/ol050208v

Bouffard J, Kim Y, Swager TM, Weissleder R, Hilderbrand SA

A Highly Selective Fluorescent Probe for Thiol Bioimaging. Org Lett. 2007;10 :37-40 - PMID: 18062694 - DOI: 10.1021/ol702539v

McCarthy JR, Jenkins HA, Bruckner C

Free base meso-tetraaryl-morpholinochlorins and porpholactone from meso-tetraaryl-2,3-dihydroxy-chlorin. Org Lett. 2003;5(1):19-22

Hilderbrand S, Weissleder R.

Optimized pH-responsive cyanine fluorochromes for detection of acidic environments Chem Commun. 2007;(26):2747-9 - PMID: 17594041 - DOI: 10.1039/b703764c

Kim YM, Hilderbrand S, Weissleder R, Tung CH

Sugar sensing based on induced pH changes Chem Commun. 2007;(22):2299-2301 - PMID: 17534523 - DOI: 10.1039/b700741h

McCarthy JR, Hyland MA, Bruckner C

Indaphyrin, a meso-tetraphenylsecochlorin-derived chromophore incorporating o-phenyl-to-β-linkages Chem Commun. 2003;:1738-9

Garanger E, Aikawa E, Reynolds F, Weissleder R, Josephson L

Simplified syntheses of complex multifunctional nanomaterials. Chem Commun. 2008;39:4792-4 - PMID: 18830495 - PMCID: PMC2692914 - DOI: 10.1039/b809537j

McCann CM, Waterman P, Figueiredo JL, Aikawa E, Weissleder R, Chen JW

Combined magnetic resonance and fluorescence imaging of the living mouse brain reveals glioma response to chemotherapy. Neuroimage. 2008;45(2):360-9 - PMID: 19154791 - PMCID: PMC2707831 - DOI: 10.1016/j.neuroimage.2008.12.022

Yuan H, Luo J, Weissleder R, Cantley L, Josephson L

Wortmannin-C20 Conjugates Generate Wortmannin. J Med Chem. 2006;49(2):740-747 - PMID: 16420059 - DOI: 10.1021/jm050699p

Galande A, Hilderbrand S, Weissleder R, Tung CH.

Enzyme-targeted fluorescent imaging probes on a multiple antigenic peptide core J Med Chem. 2006;49(15):4715-20 - PMID: 16854078 - DOI: 10.1021/jm051001a

Montet X, Funovics M, Montet-Abou K, Weissleder R, Josephson L.

Multivalent effects of RGD peptides obtained by nanoparticle display J Med Chem. 2006;49(20):6087-6093

Blois J, Yuan H, Smith A, Pacold ME, Weissleder R, Cantley LC, Josephson L

Slow Self-Activation Enhances The Potency of Viridin Prodrugs. J Med Chem. 2008;51(15):4699-707 - PMID: 18630894 - PMCID: PMC2663427 - DOI: 10.1021/jm800374f

Estiu G, Greenberg E, Harrison C, Kwiatkowski N, Mazitschek R, Bradner J, Wiest O

Structural origin of selectivity in class II-selective histone deacetylase inhibitors. J Med Chem. 2008;51:2898-906 - PMID: 18412327 - DOI: 10.1021/jm7015254

Kissau L, Stahl P, Mazitschek R, Giannis A, Waldmann H

Development of natural product-derived receptor tyrosine kinase inhibitors based on conservation of protein domain fold. J Med Chem. 2003;46(14):2917-31 - PMID: 12825933 - DOI: 10.1021/jm0307943

Kirkin V, Thiele W, Baumann P, Mazitschek R, Rohde K, Fellbrich G, Weich H, Waltenberger J, Giannis A, Sleeman JP

MAZ51, an indolinone that inhibits endothelial cell and tumor cell growth in vitro, suppresses tumor growth in vivo. Int J Cancer. 2004;112(6):986-93 - PMID: 15386354 - DOI: 10.1002/ijc.20509

Lewin M, Bredow S, Sergeyev N, Marecos E, Bogdanov A Jr, Weissleder R

In vivo assessment of vascular endothelial growth factor-induced angiogenesis Int J Cancer. 1999;83:798-802 - PMID: 10597197 - DOI: 10.1002/(sici)1097-0215(19991210)83:6<798::aid-ijc16>3.0.co;2-w

Alencar H, King R, Funovics M, Stout C, Weissleder R, Mahmood U.

A novel mouse model for segmental orthotopic colon cancer Int J Cancer. 2005;117(3):335-9 - PMID: 15900588 - DOI: 10.1002/ijc.21185

Figueiredo JL, Alencar H, Weissleder R, Mahmood U

Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer. Int J Cancer. 2006;118(11):2672-7 - PMID: 16380983 - DOI: 10.1002/ijc.21713

Gee MS, Upadhyay R, Bergquist H, Weissleder R, Josephson L, Mahmood U

Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment. Int J Cancer. 2007;(121) 11:2492-2500 - PMID: 17683072 - DOI: 10.1002/ijc.22995

Lacy-Hulbert A*, Ueno T*, Ito T, Jurewicz M, Izawa A, Smith RN, Chase CM, Tanaka K, Fiorina P, Russell PS, Auchincloss H, Sayegh MH, Hynes RO, Abdi R

Beta 3 integrins regulate lymphocyte migration and cytokine responses in heart transplant rejection. Am J Transplant. 2007;7(5):1080-90 - PMID: 17359504 - DOI: 10.1111/j.1600-6143.2007.01757.x

Bradner JE, McPherson OM, Mazitschek R, Barnes-Seeman D, Shen JP, Dhaliwal J, Stevenson KE, Duffner JL, Park SB, Neuberg DS, Nghiem P, Schreiber SL, Koehler AN

A robust small-molecule microarray platform for screening cell lysates. Chem Biol. 2006;13(5):493-504 - PMID: 16720270 - DOI: 10.1016/j.chembiol.2006.03.004

Law B, Curino A, Bugge TH, Weissleder R, Tung CH

Design, synthesis, and characterization of urokinase plasminogen-activator-sensitive near-infrared reporter. Chem Biol. 2004;11(1):99-106 - PMID: 15112999 - DOI: 10.1016/j.chembiol.2003.12.017

Yuan H, Barnes KR, Weissleder R, Cantley L, Josephson L

Covalent Reactions of Wortmannin under Physiological Conditions. Chem Biol. 2007;14(3):321-8 - PMID: 17379147 - DOI: 10.1016/j.chembiol.2007.02.007

Shepherd J, Hilderbrand SA, Waterman P, Heinecke JW, Weissleder R, Libby P

A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chem Biol. 2007;14:1221-31 - PMID: 18022561 - PMCID: PMC2785040 - DOI: 10.1016/j.chembiol.2007.10.005

Kozloff KM, Weissleder R, Mahmood U

Non-Invasive Optical Detection of Bone Mineral. J Bone Miner Res. 2007;(22) 8:1208-1216 - PMID: 17488196 - DOI: 10.1359/jbmr.070504

Sosnovik DE, Nahrendorf M, Weissleder R

Targeted imaging of myocardial damage. Nat Clin Pract Card. 2008;5 Suppl 2:S63-70 - PMID: 18641609 - PMCID: PMC2597275 - DOI: 10.1038/ncpcardio1115

Sosnovik DE, Nahrendorf M, Weissleder R

Magnetic nanoparticles for MR imaging: agents, techniques and cardiovascular applications. Basic Res Cardiol. 2008;103(2):122-30 - PMID: 18324368 - PMCID: PMC2597271 - DOI: 10.1007/s00395-008-0710-7

Nahrendorf M, Sosnovik DE, Weissleder R

MR-optical imaging of cardiovascular molecular targets. Basic Res Cardiol. 2008;103:87-94 - PMID: 18324364 - PMCID: PMC2664635 - DOI: 10.1007/s00395-008-0707-2

Groen A, Needleman D, Brangwynne C, Gradinaru C, Fowler B, Mazitschek R, Mitchison T

A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly. J Cell Sci. 2008;121(Pt 14):2293-300 - PMID: 18559893 - PMCID: PMC2902979 - DOI: 10.1242/jcs.024018

Tran AD, Marmo TP, Salam AA, Che S, Finkelstein E, Kabarriti R, Xenias HS, Mazitschek R, Hubbert C, Kawaguchi Y, Sheetz MP, Yao TP, Bulinski JC

HDAC6 deacetylation of tubulin modulates dynamics of cellular adhesions. J Cell Sci. 2007;120(Pt 8):1469-79 - PMID: 17389687 - DOI: 10.1242/jcs.03431

Sinusas AJ, Bengel F, Nahrendorf M, Epstein FH, Wu JC, Villanueva FS, Fayad ZA and Gropler RJ

Multimodality Cardiovascular Molecular Imaging, Part I Circ Cardiovasc Imaging. 2008;1(3):244-256 - PMID: 19808549 - DOI: 10.1161/CIRCIMAGING.108.824359

Nahrendorf M, Wiesmann F, Hiller K, Han H, Hu K, Waller C, Ruff J, Haase A, Ertl G, Bauer W

In vivo assessment of cardiac remodeling after myocardial infarction in rats by cine-magnetic resonance imaging. J Cardiovasc Magn Reson. 2001;2(3):171-80 - PMID: 11545114 - DOI: 10.3109/10976640009146565

Law B, Weissleder R, Tung CH

Peptide-based Biomaterials for Protease-Enhanced Drug Delivery Biomacromolecules. 2006;7(4):1261-1265 - PMID: 16602747 - DOI: 10.1021/bm050920f

Law B, Tung CH

Structural modification of protease inducible preprogrammed nanofiber precursor. Biomacromolecules. 2008;9:421-5 - PMID: 18177006 - DOI: 10.1021/bm7012026

Yoshida S, Shimada M, Ueno T, Kitamura Y, Matsuzaki S, Nishikubo S, Nagae M, Nakanishi K, Murata J, Yoshino M

Successful endoscopic submucosal dissection of duodenal cancer. Endoscopy. 2008;40 Suppl 2:E132-3 - PMID: 18633861 - DOI: 10.1055/s-2007-995685

Yoshida S, Shimada M, Ueno T, Kato A, Yoshino M

Latex hand glove: a safe and convenient device for the endoscopic removal of foreign bodies. Endoscopy. 2008;40 Suppl 2:E195-6 - PMID: 18709613 - DOI: 10.1055/s-2008-1077420

Yoshida S, Shimada M, Ueno T, Yoshino M

Exuberant mucosal granulation by a self-expanding metal stent leading to complete closure of esophageal perforation. Endoscopy. 2008;40 Suppl 2:E244-5 - PMID: 18991221 - DOI: 10.1055/s-2008-1077526

Schellenberger EA, Bogdanov A Jr, Petrovsky A, Ntziachristos V, Weissleder R, Josephson L

Optical imaging of apoptosis as a biomarker of tumor response to chemotherapy Neoplasia. 2003;5:187-92 - PMID: 12869301 - PMCID: PMC1502408 - DOI: 10.1016/S1476-5586(03)80050-7

Allport JR, Weissleder R

Murine Lewis lung carcinoma-derived endothelium expresses markers of endothelial activation and requires tumor-specific extracellular matrix in vitro Neoplasia. 2003;5:205-17 - PMID: 12869304 - PMCID: PMC1502407 - DOI: 10.1016/S1476-5586(03)80053-2

Messerli SM, Tang Y, Giovannini M, Bronson R, Weissleder R, Breakefield XO

Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2 Neoplasia. 2002;4:501-9 - PMID: 12407444 - PMCID: PMC1503664 - DOI: 10.1038/sj.neo.7900265

Melder RJ, Munn LL, Stoll BR, Marecos EM, Baxter LT, Weissleder R, Jain RK

Systemic distribution and tumor localization of adoptively transferred lymphocytes in mice: comparison with physiologically based pharmacokinetic model Neoplasia. 2002;4:3-8 - PMID: 11922388 - PMCID: PMC1503314 - DOI: 10.1038/sj/neo/7900209

Ichikawa T, Hogemann D, Saeki Y, Tyminski E, Terada K, Weissleder R, Chiocca EA, Basilion JP

MRI of transgene expression: correlation to therapeutic gene expression Neoplasia. 2002;4:523-30 - PMID: 12407446 - PMCID: PMC1503666 - DOI: 10.1038/sj.neo.7900266

Bogdanov AA Jr, Lin CP, Simonova M, Matuszewski L, Weissleder R

Cellular activation of the self-quenched fluorescent reporter probe in tumor microenvironment Neoplasia. 2002;4:228-36 - PMID: 11988842 - PMCID: PMC1531696 - DOI: 10.1038/sj/neo/7900238

Bogdanov A Jr, Marecos E, Cheng HC, Chandrasekaran L, Krutzsch HC, Roberts DD, Weissleder R

Treatment of experimental brain tumors with trombospondin-1 derived peptides: an in vivo imaging study Neoplasia. 1999;1:438-45 - PMID: 10933059 - PMCID: PMC1508110 - DOI: 10.1038/sj.neo.7900044

Hogemann-Savellano D, Bos E, Blondet C, Sato F, Abe T, Josephson L, Weissleder R, Gaudet J, Sgroi D, Peters PJ, Basilion JP.

The transferrin receptor: a potential molecular imaging marker for human cancer. Neoplasia. 2003;5(6):495-506 - PMID: 14965443 - PMCID: PMC1502574 - DOI: 10.1016/s1476-5586(03)80034-9

Messerli SM, Prabhakar S, Tang Y, Shah K, Cortes ML, Murthy V, Weissleder R, Breakefield XO, Tung CH

A novel method for imaging apoptosis using a caspase-1 near-infrared fluorescent probe. Neoplasia. 2004;6(2):95-105 - PMID: 15140398 - PMCID: PMC1502090 - DOI: 10.1593/neo.03214

Shinde Patil VR, Friedrich EB, Wolley AE, Gerszten RE, Allport JR, Weissleder R.

Bone Marrow-Derived lin(-)c-kit(+)Sca-1(+) Stem Cells Do Not Contribute to Vasculogenesis in Lewis Lung Carcinoma Neoplasia. 2005;7(3):234-40 - PMID: 15799823 - PMCID: PMC1501134 - DOI: 10.1593/neo.04523

Reichardt W, Hu-Lowe D, Torres D, Weissleder R, Bogdanov A Jr.

Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model Neoplasia. 2005;7(9):847-53 - PMID: 16229807 - PMCID: PMC1351316 - DOI: 10.1593/neo.05139

Funovics M, Montet X, Reynolds F, Weissleder R, Josephson L.

Nanoparticles for the Optical Imaging of Tumor E-selectin Neoplasia. 2005;7(10):904-11 - PMID: 16242073 - DOI: 10.1593/neo.05352

Alencar H, Mahmood U, Kawano Y, Hirata T, Weissleder R

Novel Multiwavelength Microscopic Scanner for Mouse Imaging. Neoplasia. 2005;7(11):977-983 - PMID: 16331883 - PMCID: PMC1502018 - DOI: 10.1593/neo.05376

Sato F, Fukuhara H, Basilion JP

Effects of hormone deprivation and 2-methoxyestradiol combination therapy on hormone-dependent prostate cancer in vivo. Neoplasia. 2005;7(9):838-46 - PMID: 16229806 - PMCID: PMC1501932 - DOI: 10.1593/neo.05145

Montet X, Montet-Abou K, Reynolds F, Weissleder R, Josephson L.

Nanoparticle Imaging of Integrins on Tumor Cells Neoplasia. 2006;8(3):214-222 - PMID: 16611415 - PMCID: PMC1578521 - DOI: 10.1593/neo.05769

Trehin R, Figueiredo JL, Pittet M, Weissleder R, Josephson L, Mahmood U.

Fluorescent Nanoparticle Uptake for Brain Tumor Visualization Neoplasia. 2006;8(4):302-311 - PMID: 16756722 - PMCID: PMC1600680 - DOI: 10.1593/neo.05751

Newton JR, Kelly KA, Mahmood U, Weissleder R, Deutscher SL

In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice. Neoplasia. 2006;8(9):772-80 - PMID: 16984734 - PMCID: PMC1584300 - DOI: 10.1593/neo.06331

Kelly KA, Waterman P, Weissleder R.

In vivo imaging of molecularly targeted phage Neoplasia. 2006;8 (12):1011-1018

Kock N, Kasmieh R, Weissleder R, Shah K

Tumor Therapy Mediated by Lentiviral Expression of shBcl-2 and S-TRAIL. Neoplasia. 2007;9(5):435-42 - PMID: 17534449 - PMCID: PMC1877976 - DOI: 10.1593/neo.07223

Harisinghani M, Ross R, Guimaraes A, Weissleder R

Utility of a New Bolus-Injectable Nanoparticle for Clinical Cancer Staging Neoplasia. 2007;(9)12:1160-1165 - PMID: 18084623 - PMCID: PMC2134912 - DOI: 10.1593/neo.07940

Kelly K, Jones D

Isolation of a colon tumor specific binding peptide using phage display selection. Neoplasia. 2003;5:437-44 - PMID: 14670181 - PMCID: PMC1550331 - DOI: 10.1016/s1476-5586(03)80046-5

Perez JM, Grimm J, Josephson L, Weissleder R

Integrated nanosensors to determine levels and functional activity of human telomerase. Neoplasia. 2008;10(10):1066-72 - PMID: 18813356 - PMCID: PMC2546593 - DOI: 10.1593/neo.08350

Kim DE, Jaffer FA, Weissleder R, Tung CH, Schellingerhout D.

Near-infrared fluorescent imaging of cerebral thrombi and blood-brain barrier disruption in a mouse model of cerebral venous sinus thrombosis J Cereb Blood Flow Metab. 2005;25(2):226-33 - PMID: 15678125 - DOI: 10.1038/sj.jcbfm.9600023

Mahmood U, Weissleder R

Near-infrared optical imaging of proteases in cancer Mol Cancer Ther. 2003;2:489-96 - PMID: 12748311

Law B, Quinti L, Choi YD, Weissleder R, Tung CH

A Mitochondrial Targeted Fusion Peptide Exhibits Remarkable Cytotoxicity Mol Cancer Ther. 2006;5 (8):1944-1949 - PMID: 16928814 - DOI: 10.1158/1535-7163.MCT-05-0509

Hingtgen S, Ren X, Terwilliger E, Classon M, Weissleder R, Shah K

Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol Cancer Ther. 2008;7(11):3575-85 - PMID: 19001440 - PMCID: PMC2748233 - DOI: 10.1158/1535-7163.MCT-08-0640

Framme C, Alt C, Schnell S, Brinkmann R, Lin CP

[Selective RPE laser treatment with a scanned cw laser beam in rabbits] Ophthalmologie. 2005;102(5):491-6 - PMID: 15883846 - DOI: 10.1007/s00347-004-1139-5

Vianello F, Papeta N, Chen T, Kraft P, White N, Hart WK, Kircher MF, Swart E, Rhee S, Palu G, Irimia D, Toner M, Weissleder R, Poznansky MC

Murine B16 Melanomas Expressing High Levels of the Chemokine Stromal-Derived Factor-1/CXCL12 Induce Tumor-Specific T Cell Chemorepulsion and Escape from Immune Control. J Immunol. 2006;176(5):2902-14 - PMID: 16493048 - DOI: 10.4049/jimmunol.176.5.2902

Campanella GS, Grimm J, Manice LA, Colvin RA, Medoff BD, Wojtkiewicz GR, Weissleder R, Luster AD

Oligomerization of CXCL10 Is Necessary for Endothelial Cell Presentation and In Vivo Activity. J Immunol. 2006;177:6991-8 - PMID: 17082614 - DOI: 10.4049/jimmunol.177.10.6991

Pittet M, Gati A, Le Gal F, Bioley G, Guillaume P, de Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Zippelius A

Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex. J Immunol. 2006;176:2330-6 - PMID: 16455990 - DOI: 10.4049/jimmunol.176.4.2330

Zippelius A, Bioley G, Le Gal F, Rufer N, Brandes M, Batard P, De Smedt M, Plum J, Speiser D, Cerottini J, Dietrich P, Romero P, Pittet M

Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues. J Immunol. 2004;172:2773-7 - PMID: 14978076 - DOI: 10.4049/jimmunol.172.5.2773

Pittet M, Rubio-Godoy V, Bioley G, Guillaume P, Batard P, Speiser D, Luescher I, Cerottini J, Romero P, Zippelius A

Alpha 3 domain mutants of peptide/MHC class I multimers allow the selective isolation of high avidity tumor-reactive CD8 T cells. J Immunol. 2003;171:1844-9 - PMID: 12902485 - DOI: 10.4049/jimmunol.171.4.1844

Dietrich P, Le Gal F, Dutoit V, Pittet M, Trautman L, Zippelius A, Cognet I, Widmer V, Walker P, Michielin O, Guillaume P, Connerotte T, Jotereau F, Coulie P, Romero P, Cerottini J, Bonneville M, Valmori D

Prevalent role of TCR alpha-chain in the selection of the preimmune repertoire specific for a human tumor-associated self-antigen. J Immunol. 2003;170:5103-9 - PMID: 12734356 - DOI: 10.4049/jimmunol.170.10.5103

Valmori D, Dutoit V, Schnuriger V, Quiquerez A, Pittet M, Guillaume P, Rubio-Godoy V, Walker P, Rimoldi D, Lienard D, Cerottini J, Romero P, Dietrich P

Vaccination with a Melan-A peptide selects an oligoclonal T cell population with increased functional avidity and tumor reactivity. J Immunol. 2002;168:4231-40 - PMID: 11937585 - DOI: 10.4049/jimmunol.168.8.4231

Pittet M, Zippelius A, Speiser D, Assenmacher M, Guillaume P, Valmori D, Lienard D, Lejeune F, Cerottini J, Romero P

Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases. J Immunol. 2001;166:7634-40 - PMID: 11390521 - DOI: 10.4049/jimmunol.166.12.7634

Speiser D, Colonna M, Ayyoub M, Cella M, Pittet M, Batard P, Valmori D, Guillaume P, Lienard D, Cerottini J, Romero P

The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells. J Immunol. 2001;167:6165-70 - PMID: 11714776 - DOI: 10.4049/jimmunol.167.11.6165

Pittet M, Speiser D, Valmori D, Cerottini J, Romero P

Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression. J Immunol. 2000;164:1148-52 - PMID: 10640724 - DOI: 10.4049/jimmunol.164.3.1148

Alvarez D, Swirski F, Yang T, Fattouh R, Croitoru K, Bramson J, Stampfli M, Jordana M

Inhalation tolerance is induced selectively in thoracic lymph nodes but executed pervasively at distant mucosal and nonmucosal tissues. J Immunol. 2006;176(4):2568-80 - PMID: 16456019 - DOI: 10.4049/jimmunol.176.4.2568

Gajewska B, Tafuri A, Swirski F, Walker T, Johnson J, Shea T, Shahinian A, Goncharova S, Mak T, Stampfli M, Jordana M

B7RP-1 is not required for the generation of Th2 responses in a model of allergic airway inflammation but is essential for the induction of inhalation tolerance. J Immunol. 2005;174(5):3000-5 - PMID: 15728513 - DOI: 10.4049/jimmunol.174.5.3000

Swirski F, Sajic D, Robbins C, Gajewska B, Jordana M, Stampfli M

Chronic exposure to innocuous antigen in sensitized mice leads to suppressed airway eosinophilia that is reversed by granulocyte macrophage colony-stimulating factor. J Immunol. 2002;169:3499-506 - PMID: 12244139 - DOI: 10.4049/jimmunol.169.7.3499

Romero P, Zippelius A, Kurth I, Pittet M, Touvrey C, Iancu E, Corthesy P, Devevre E, Speiser D, Rufer N

Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes. J Immunol. 2007;178(7):4112-9 - PMID: 17371966 - DOI: 10.4049/jimmunol.178.7.4112

Ito T*, Ueno T*, Clarkson MR, Yuan X, Jurewicz MM, Yagita H, Azuma M, Sharpe AH, Auchincloss H, Sayegh MH, Najafian N

Analysis of the role of negative T cell costimulatory pathways in CD4 and CD8 T cell-mediated alloimmune responses in vivo. J Immunol. 2005;174(11):6648-56 - PMID: 15905503 - DOI: 10.4049/jimmunol.174.11.6648

Izawa A, Yamaura K, Albin MJ, Jurewicz M, Tanaka K, Clarkson MR, Ueno T, Habicht A, Freeman GJ, Yagita H, Abdi R, Pearson T, Greiner DL, Sayegh MH, Najafian N

A novel alloantigen-specific CD8+PD1+ regulatory T cell induced by ICOS-B7h blockade in vivo. J Immunol. 2007;179(2):786-96 - PMID: 17617568 - DOI: 10.4049/jimmunol.179.2.786

Tanaka K, Albin MJ, Yuan X, Yamaura K, Habicht A, Murayama T, Grimm M, Waaga AM, Ueno T, Padera RF, Yagita H, Azuma M, Shin T, Blazar BR, Rothstein DM, Sayegh MH, Najafian N

PDL1 is required for peripheral transplantation tolerance and protection from chronic allograft rejection. J Immunol. 2007;179(8):5204-10 - PMID: 17911605 - PMCID: PMC2291549 - DOI: 10.4049/jimmunol.179.8.5204

Marshansky V, Wang X, Bertrand R, Luo H, Duguid W, Chinnadurai G, Kanaan N, Vu MD, Wu J

Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells. J Immunol. 2001;166(5):3130-42 - PMID: 11207265 - DOI: 10.4049/jimmunol.166.5.3130

Frank H, Loewe R, Loewe C, Oberhuber G, Schwaighofer B, Huber K, Weissleder R

Efficacy of thrombolytic therapy in pulmonary embolism determined by MION-enhanced MRA: an experimental study in rabbits. Invest Radiol. 1998;33(12):853-7 - PMID: 9851818 - DOI: 10.1097/00004424-199812000-00002

Cheng HC, Khan MA, Bogdanov A, Kwong K, Weissleder R

Relative blood volume measurements by magnetic resonance imaging facilitate detection of testicular torsion. Invest Radiol. 1997;32(12):763-9 - PMID: 9406017 - DOI: 10.1097/00004424-199712000-00007

Schulze E, Ferrucci JT, Poss K, Lapointe L, Bogdanova A, Weissleder R

Cellular uptake and trafficking of a prototypical magnetic iron oxide label in vitro. Invest Radiol. 1995;30(10):604-10 - PMID: 8557500 - DOI: 10.1097/00004424-199510000-00006

Weissleder R, Bogdanov A, Frank H, Nossiff N, Bogdanova A, Schaffer BK, Brady T, Wittenberg J

AUR Memorial Award 1993. A drug system (PDH) for interventional radiology. Synthesis, properties, and efficacy. Invest Radiol. 1993;28(12):1083-9 - PMID: 8307710 - DOI: 10.1097/00004424-199312000-00001

Reimer P, Weissleder R, Nickeleit V, Brady TJ

Animal models for magnetic resonance imaging research of the liver. Invest Radiol. 1992;27(5):390-3 - PMID: 1582824 - DOI: 10.1097/00004424-199205000-00014

Bremer C, Ntziachristos V, Weitkamp B, Theilmeier G, Heindel W, Weissleder R.

Optical Imaging of Spontaneous Breast Tumors Using Protease Sensing Invest Radiol. 2005;(6):321-327 - PMID: 15905717 - DOI: 10.1097/01.rli.0000163797.23172.90

Grüber G, Marshansky V

New insights into structure-function relationships between archeal ATP synthase (A1A0) and vacuolar type ATPase (V1V0). Bioessays. 2008;30(11-12):1096-109 - PMID: 18937357 - DOI: 10.1002/bies.20827

Deramaudt TB, Takaoka M, Upadhyay R, Bowser MJ, Porter J, Lee A, Rhoades B, Johnstone CN, Weissleder R, Hingorani SR, Mahmood U, Rustgi AK

N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell Migration, Invasion, and Tissue Architecture Disruption. Mol Cell Biol. 2006;26(11):4185-200 - PMID: 16705170 - PMCID: PMC1489079 - DOI: 10.1128/MCB.01055-05

Gabriely G, Wurdinger T, Kesari S, Esau C, Burchard J, Linsley P, Krichevsky A

MiR-21 Promotes Glioma Invasion by Targeting MMP Regulators. Mol Cell Biol. 2008;28(17):5369-80 - PMID: 18591254 - PMCID: PMC2519720 - DOI: 10.1128/MCB.00479-08

Shah K, Breakefield XO

HSV Amplicon Vectors for Cancer Therapy. Curr Gene Ther. 2006;6(3):361-70 - PMID: 16787187 - DOI: 10.2174/156652306777592063

Shayakul C, Breton S, Brown D, Alper SL

Gene therapy of inherited renal tubular disease. Am J Kidney Dis. 1999;34(2):374-9 - PMID: 10430991 - DOI: 10.1016/s0272-6386(99)70372-0

King JC, Moskowitz IP, Burgon PG, Ahmad F, Stone JR, Seidman JG, Lees JA

E2F3 plays an essential role in cardiac development and function. Cell Cycle. 2008;7(23):3775-80 - PMID: 19029823 - PMCID: PMC2723769 - DOI: 10.4161/cc.7.23.7240

Funovics MA, Alencar H, Montet X, Weissleder R, Mahmood U

Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization. Gastrointest Endosc. 2006;64(4):589-97 - PMID: 16996355 - DOI: 10.1016/j.gie.2006.02.048

Jaffer FA, Sosnovik DE, Nahrendorf M, Weissleder R

Molecular imaging of myocardial infarction. J Mol Cell Cardiol. 2006;41:921-933 - PMID: 17067633 - DOI: 10.1016/j.yjmcc.2006.09.008

Yen L, Magnier M, Weissleder R, Stockwell BR, Mulligan RC

Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA. 2006;12(5):797-806 - PMID: 16556935 - PMCID: PMC1440893 - DOI: 10.1261/rna.2300406

Lohse MJ, Hein P, Hoffmann C, Nikolaev VO, Vilardaga JP, Bunemann M

Kinetics of G-protein-coupled receptor signals in intact cells. Brit J Pharmacol. 2008;153 Suppl 1:S125-32 - PMID: 18193071 - PMCID: PMC2268076 - DOI: 10.1038/sj.bjp.0707656

Bredow S, Lewin M, Hofmann B, Marecos E, Weissleder R

Imaging of tumour neovasculature by targeting the TGF-beta binding receptor endoglin Eur J Cancer. 2000;36:675-81 - PMID: 10738134 - DOI: 10.1016/s0959-8049(99)00335-4

Weissleder R, Cheng HC, Marecos E, Kwong K, Bogdanov A

Non-invasive in vivo mapping of tumour vascular and interstitial volume fractions. Eur J Cancer. 1998;34(9):1448-54 - PMID: 9849430 - DOI: 10.1016/s0959-8049(98)00195-6

Stieber F, Grether U, Mazitschek R, Soric N, Giannis A, Waldmann H

Multistep solid-phase synthesis of an antibiotic and receptor tyrosine kinase inhibitors using the traceless phenylhydrazide linker. Chemistry. 2003;9(14):3282-91 - PMID: 12866072 - DOI: 10.1002/chem.200304821

Speiser D, Lienard D, Pittet M, Batard P, Rimoldi D, Guillaume P, Cerottini J, Romero P

In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells. Eur J Immunol. 2002;32:731-41 - PMID: 11870617 - DOI: 10.1002/1521-4141(200203)32:3<731::AID-IMMU731>3.0.CO;2-H

Speiser D, Migliaccio M, Pittet M, Valmori D, Lienard D, Lejeune F, Reichenbach P, Guillaume P, Lascher I, Cerottini J, Romero P

Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells. Eur J Immunol. 2001;31:459-66 - PMID: 11180110 - DOI: 10.1002/1521-4141(200102)31:2<459::aid-immu459>3.0.co;2-y

Speiser D, Valmori D, Rimoldi D, Pittet M, Lienard D, Cerundolo V, MacDonald H, Cerottini J, Romero P

CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients. Eur J Immunol. 1999;29:1990-9 - PMID: 10382762 - DOI: 10.1002/(SICI)1521-4141(199906)29:06<1990::AID-IMMU1990>3.0.CO;2-9

Swirski F, Gajewska B, Robbins C, D'Sa A, Johnson J, Pouladi M, Inman M, Stampfli M

Concomitant airway expression of granulocyte-macrophage colony-stimulating factor and decorin, a natural inhibitor of transforming growth factor-beta, breaks established inhalation tolerance. Eur J Immunol. 2004;34(9):2375-86 - PMID: 15307170 - DOI: 10.1002/eji.200425012

Galande A, Weissleder R, Tung CH.

An Effective Method of On-Resin Disulfide Bond Formation in Peptides J Comb Chem. 2005;7:174-177 - PMID: 15762743 - DOI: 10.1021/cc049839r

Weissleder R, Marfil A, Martinez HR, Rangel-Guerra RA

Limb girdle type muscular dystrophy associated with a Wolff-Parkinson-White syndrome. J Neurol Neurosurg Psych. 1987;50(4):500-1 - PMID: 3585373 - PMCID: PMC1031899 - DOI: 10.1136/jnnp.50.4.500

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Clinical pulmonary autograft valves: pathologic evidence of adaptive remodeling in the aortic site. J Thorac Cardiovasc Surg. 2004;128:552-61 - PMID: 15457156 - DOI: 10.1016/j.jtcvs.2004.04.016

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A rapid enzymatic method for the isolation of defined kidney tubule fragments from mouse. Pflug Arch Eur J Phy. 2003;446(5):623-32 - PMID: 12748863 - DOI: 10.1007/s00424-003-1082-3

Swirski F, Gajewska B, Alvarez D, Ritz S, Cundall M, Cates E, Coyle A, Gutierrez-Ramos J, Inman M, Jordana M, Stampfli M

Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice. Clin Exp Allergy. 2002;32:411-21 - PMID: 11940072 - DOI: 10.1046/j.1365-2222.2002.01291.x

Alvarez de la Rosa D, Paunescu TG, Els WJ, Helman SI, Canessa CM

Mechanisms of regulation of epithelial sodium channel by SGK1 in A6 cells. J Gen Physiol. 2004;124(4):395-407 - PMID: 15452200 - PMCID: PMC2233909 - DOI: 10.1085/jgp.200409120

Li C, Breton S, Morrison R, Cannon CL, Emma F, Sanchez-Olea R, Bear C, Strange K

Recombinant pICln forms highly cation-selective channels when reconstituted into artificial and biological membranes. J Gen Physiol. 1998;112(6):727-36 - PMID: 9834142 - PMCID: PMC2229450 - DOI: 10.1085/jgp.112.6.727

Xia Y, Sidis Y, Mukherjee A, Samad TA, Brenner G, Woolf CJ, Lin HY, Schneyer A

Localization and action of Dragon (repulsive guidance molecule b), a novel bone morphogenetic protein coreceptor, throughout the reproductive axis. Endocrinology. 2005;146(8):3614-21 - PMID: 15890774 - PMCID: PMC1351303 - DOI: 10.1210/en.2004-1676

Hilderbrand S, Lippard S

Cobalt chemistry with mixed aminotroponiminate salicylaldiminate ligands: synthesis, characterization, and nitric oxide reactivity. Inorg Chem. 2004;43:4674-82 - PMID: 15257596 - DOI: 10.1021/ic049776h

Hilderbrand S, Lippard S

Nitric oxide reactivity of fluorophore coordinated carboxylate-bridged diiron(II) and dicobalt(II) complexes. Inorg Chem. 2004;43:5294-301 - PMID: 15310207 - DOI: 10.1021/ic049649l

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Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorg Chem. 2004;43:2624-35 - PMID: 15074981 - DOI: 10.1021/ic035158+

Beaulieu V, Da Silva N, Pastor-Soler N, Brown CR, Smith PJ, Brown D, Breton S

Modulation of the actin cytoskeleton via gelsolin regulates vacuolar H+-ATPase recycling. J Biol Chem. 2005;280(9):8452-63 - PMID: 15591047 - DOI: 10.1074/jbc.M412750200

Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D

Heat shock protein 70 interacts with aquaporin-2 (AQP2) and regulates its trafficking. J Biol Chem. 2007;282(39):28721-32 - PMID: 17636261 - DOI: 10.1074/jbc.M611101200

Pietrement C, Da Silva N, Silberstein C, James M, Marsolais M, Van Hoek A, Brown D, Pastor-Soler N, Ameen N, Laprade R, Ramesh V, Breton S

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NFATc1 mediates vascular endothelial growth factor-induced proliferation of human pulmonary valve endothelial cells. J Biol Chem. 2003;278:1686-92 - PMID: 12427739 - PMCID: PMC2813494 - DOI: 10.1074/jbc.M210250200

Shah K, Vervoort J, de Vries S

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Xia Y, Yu P, Sidis Y, Beppu H, Bloch K, Schneyer A, Lin H

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4. J Biol Chem. 2007;282(25):18129-40 - PMID: 17472960 - DOI: 10.1074/jbc.M701679200

Babitt J, Zhang Y, Samad T, Xia Y, Tang J, Campagna J, Schneyer A, Woolf C, Lin HY

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor. J Biol Chem. 2005;280(33):29820-7 - PMID: 15975920 - DOI: 10.1074/jbc.M503511200

del Re E, Sidis Y, Fabrizio D, Lin HY, Schneyer A

Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system. J Biol Chem. 2004;279(51):53126-35 - PMID: 15475360 - DOI: 10.1074/jbc.M408090200

del Re E, Babitt J, Pirani A, Schneyer A, Lin HY

In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2. J Biol Chem. 2004;279(21):22765-72 - PMID: 14996829 - DOI: 10.1074/jbc.M401350200

Hasler U, Nunes P, Bouley R, Lu HA, Matsuzaki T, Brown D

Acute hypertonicity alters aquaporin-2 trafficking and induces a MAP kinase-dependent accumulation at the plasma membrane of renal epithelial cells. J Biol Chem. 2008;283(39):26643-61 - PMID: 18664568 - PMCID: PMC2546545 - DOI: 10.1074/jbc.M801071200

Schuetz A, Min J, Allali-Hassani A, Schapira M, Shuen M, Loppnau P, Mazitschek R, Kwiatkowski N, Lewis T, Maglathin R, McLean T, Bochkarev A, Plotnikov A, Vedadi M, Arrowsmith C

Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. J Biol Chem. 2008;283(17):11355-63 - PMID: 18285338 - PMCID: PMC2431080 - DOI: 10.1074/jbc.M707362200

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Breton S, Wiederhold T, Marshansky V, Nsumu NN, Ramesh V, Brown D

The B1 subunit of the H+ATPase is a PDZ domain-binding protein. Colocalization with NHE-RF in renal B-intercalated cells. J Biol Chem. 2000;275(24):18219-24 - PMID: 10748165 - DOI: 10.1074/jbc.M909857199

Pastor-Soler N, Beaulieu V, Litvin TN, Da Silva N, Chen Y, Brown D, Buck J, Levin LR, Breton S

Bicarbonate-regulated adenylyl cyclase (sAC) is a sensor that regulates pH-dependent V-ATPase recycling. J Biol Chem. 2003;278(49):49523-9 - PMID: 14512417 - PMCID: PMC3652382 - DOI: 10.1074/jbc.M309543200

van Balkom BW, van Raak M, Breton S, Pastor-Soler N, Bouley R, van der Sluijs P, Brown D, Deen PM

Hypertonicity is involved in redirecting the aquaporin-2 water channel into the basolateral, instead of the apical, plasma membrane of renal epithelial cells. J Biol Chem. 2002;278(2):1101-7 - PMID: 12374804 - DOI: 10.1074/jbc.M207339200

Samad TA, Rebbapragada A, Bell E, Zhang Y, Sidis Y, Jeong SJ, Campagna JA, Perusini S, Fabrizio DA, Schneyer AL, Lin HY, Brivanlou AH, Attisano L, Woolf CJ

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Maranda B, Brown D, Bourgoin S, Casanova JE, Vinay P, Ausiello DA, Marshansky V

Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomes. J Biol Chem. 2001;276(21):18540-50 - PMID: 11278939 - DOI: 10.1074/jbc.M011577200

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Restoration of liver mass after injury requires proliferative and not embryonic transcriptional patterns. J Biol Chem. 2007;282(15):11197-204 - PMID: 17227769 - DOI: 10.1074/jbc.M608441200

Zimmer C, Wright SC, Engelhardt RT, Johnson GA, Kramm C, Breakefield XO, Weissleder R

Tumor cell endocytosis imaging facilitates delineation of the glioma-brain interface. Exp Neurol. 1997;143(1):61-9 - PMID: 9000446 - DOI: 10.1006/exnr.1996.6350

Enochs WS, Schaffer B, Bhide PG, Nossiff N, Papisov M, Bogdanov A, Brady TJ, Weissleder R

MR imaging of slow axonal transport in vivo. Exp Neurol. 1993;123(2):235-42 - PMID: 8405287 - DOI: 10.1006/exnr.1993.1156

Pai SI, Lin YY, Macaes B, Meneshian A, Hung CF, Wu TC

Prospects of RNA interference therapy for cancer. Gene Ther. 2006;13(6):464-77 - PMID: 16341059 - DOI: 10.1038/sj.gt.3302694

Kim JW, Hung CF, Juang J, He L, Kim TW, Armstrong DK, Pai SI, Chen PJ, Lin CT, Boyd DA, Wu TC

Comparison of HPV DNA vaccines employing intracellular targeting strategies. Gene Ther. 2004;11(12):1011-8 - PMID: 14985791 - DOI: 10.1038/sj.gt.3302252

Wang TL, Ling M, Shih IM, Pham T, Pai SI, Lu Z, Kurman RJ, Pardoll DM, Wu TC

Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity. Gene Ther. 2000;7(9):726-33 - PMID: 10822298 - DOI: 10.1038/sj.gt.3301160

Bogdanov A Jr, Tung CH, Bredow S, Weissleder R

DNA binding chelates for nonviral gene delivery imaging Gene Ther. 2001;8:515-22 - PMID: 11319618 - DOI: 10.1038/sj.gt.3301410

Schellingerhout D, Rainov NG, Breakefield XO, Weissleder R

Quantitation of HSV mass distribution in a rodent brain tumor model Gene Ther. 2000;7:1648-55 - PMID: 11083473 - DOI: 10.1038/sj.gt.3301272

Shah K, Jacobs A, Breakefield XO, Weissleder R

Molecular imaging of gene therapy for cancer Gene Ther. 2004;11(15):1175-87 - PMID: 15141158 - DOI: 10.1038/sj.gt.3302278

Moore A, Basilion JP, Chiocca EA, Weissleder R

Measuring transferrin receptor gene expression by NMR imaging. Biochim Biophys Acta. 1998;1402(3):239-49 - PMID: 9606982 - DOI: 10.1016/s0167-4889(98)00002-0

Bogdanov A, Simonova M, Weissleder R

Design of metal-binding green fluorescent protein variants. Biochim Biophys Acta. 1998;1397(1):56-64 - PMID: 9545533 - DOI: 10.1016/s0167-4781(97)00221-2

Bogdanov AA, Martin C, Weissleder R, Brady TJ

Trapping of dextran-coated colloids in liposomes by transient binding to aminophospholipid: preparation of ferrosomes. Biochim Biophys Acta. 1994;1193(1):212-8 - PMID: 7518693 - DOI: 10.1016/0005-2736(94)90350-6

Da Silva N, Pietrement C, Brown D, Breton S

Segmental and cellular expression of aquaporins in the male excurrent duct. Biochim Biophys Acta. 2006;1758(8):1025-33 - PMID: 16935257 - DOI: 10.1016/j.bbamem.2006.06.026

Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R

SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration. J Leukocyte biol. 2006;81(3):748-56 - PMID: 17178915 - DOI: 10.1189/jlb.1105664

Weissleder R, Poss K, Wilkinson R, Zhou C, Bogdanov A

Quantitation of slow drug release from an implantable and degradable gentamicin conjugate by in vivo magnetic resonance imaging. Antimicrob Agents Chemother. 1995;39(4):839-45 - PMID: 7785981 - PMCID: PMC162639 - DOI: 10.1128/aac.39.4.839

Huang X, Im H, Lee D, Kim H, Choi Y

Ferrocene Functionalized Single-Walled Carbon Nanotube Bundles. Hybrid Interdigitated Construction Film for l-Glutamate Detection J Phys Chem C. 2007;111(3):1200-1206

Korngold EC, Jaffer FA, Weissleder R, Sosnovik DE

Noninvasive imaging of apoptosis in cardiovascular disease. Heart Fail Rev. 2008;13(2)::163-173 - PMID: 18074226 - PMCID: PMC2597223 - DOI: 10.1007/s10741-007-9068-4

Tung CH, Quinti L, Jaffer F, Weissleder R

A Branched Fluorescent Peptide Probe for Imaging of Activated Platelets Mol Pharmacol. 2005;2:92-95 - PMID: 15804182 - DOI: 10.1021/mp0499048

Duan Z, Bradner J, Greenberg E, Mazitschek R, Foster R, Mahoney J, Seiden MV

8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid (SD-1008), a novel janus kinase 2 inhibitor, increases chemotherapy sensitivity in human ovarian cancer cells. Mol Pharmacol. 2007;72(5):1137-45 - PMID: 17675586 - DOI: 10.1124/mol.107.038117

Bogdanov AA, Lin CP, Kang HW

Optical imaging of the adoptive transfer of human endothelial cells in mice using anti-human CD31 monoclonal antibody. Pharmacol Res. 2007;24:1186-92 - PMID: 17373582 - PMCID: PMC2795329 - DOI: 10.1007/s11095-006-9219-7

Roedl JB, Harisinghani MG, Colen RR, Fischman AJ, Blake MA, Mathisen DJ, Mueller PR

Assessment of treatment response and recurrence in esophageal carcinoma based on tumor length and standardized uptake value on positron emission tomography-computed tomography. Ann Thorac Surg. 2008;86:1131-8 - PMID: 18805147 - DOI: 10.1016/j.athoracsur.2008.05.019

Chen WT, Mahmood U, Weissleder R, Tung CH

Arthritis imaging using a near-infrared fluorescence folate-targeted probe Arthritis Res Ther. 2005;7:R310-R317 - PMID: 15743478 - PMCID: PMC1065321 - DOI: 10.1186/ar1483

Graves EE, Weissleder R, Ntziachristos V

Fluorescence molecular imaging of small animal tumor models. Curr Mol Med. 2004;4(4):419-30 - PMID: 15354872 - DOI: 10.2174/1566524043360555

Russo LM, Brown D, Lin HY

The soluble transforming growth factor-beta receptor: Advantages and applications. Int J Biochem Cell B. 2008;41(3):472-6 - PMID: 18339576 - DOI: 10.1016/j.biocel.2008.01.026

Robbins C, Dawe D, Goncharova S, Pouladi M, Drannik A, Swirski F, Cox G, Stampfli M

Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness. Am J Respir Cell Mol Biol. 2004;30(2):202-11 - PMID: 12920055 - DOI: 10.1165/rcmb.2003-0259OC

Pouladi M, Robbins C, Swirski F, Cundall M, McKenzie A, Jordana M, Shapiro S, Stampfli M

Interleukin-13-dependent expression of matrix metalloproteinase-12 is required for the development of airway eosinophilia in mice. Am J Respir Cell Mol Biol. 2004;30(1):84-90 - PMID: 12842850 - DOI: 10.1165/rcmb.2003-0051OC

Gajewska B, Swirski F, Alvarez D, Ritz S, Goncharova S, Cundall M, Snider D, Coyle A, Gutierrez-Ramos J, Stampfli M, Jordana M

Temporal-spatial analysis of the immune response in a murine model of ovalbumin-induced airways inflammation. Am J Respir Cell Mol Biol. 2001;25:326-34 - PMID: 11588010 - DOI: 10.1165/ajrcmb.25.3.4482

Lasser T, Ntziachristos V

Optimization of 360 degrees projection fluorescence molecular tomography. Med Image Anal. 2007;11(4):389-99 - PMID: 17524701 - DOI: 10.1016/j.media.2007.04.003

Nahrendorf M, Hiller K, Hu K, Ertl G, Haase A, Bauer W

Cardiac magnetic resonance imaging in small animal models of human heart failure. Med Image Anal. 2003;7(3):369-75 - PMID: 12946475 - DOI: 10.1016/s1361-8415(03)00011-2

Paranya G, Vineberg S, Dvorin E, Kaushal S, Roth S, Rabkin E, Schoen F, Bischoff J

Aortic valve endothelial cells undergo transforming growth factor-beta-mediated and non-transforming growth factor-beta-mediated transdifferentiation in vitro. Am J Pathol. 2001;159:1335-43 - PMID: 11583961 - PMCID: PMC1850524 - DOI: 10.1016/s0002-9440(10)62520-5

Muldoon LL, Nilaver G, Kroll RA, Pagel MA, Breakefield XO, Chiocca EA, Davidson BL, Weissleder R, Neuwelt EA

Comparison of intracerebral inoculation and osmotic blood-brain barrier disruption for delivery of adenovirus, herpesvirus, and iron oxide particles to normal rat brain. Am J Pathol. 1995;147(6):1840-51 - PMID: 7495307 - PMCID: PMC1869962

Jensen LJ, Schmitt BM, Berger UV, Nsumu NN, Boron WF, Hediger MA, Brown D, Breton S

Localization of sodium bicarbonate cotransporter (NBC) protein and messenger ribonucleic acid in rat epididymis. Biol Reprod. 1999;60(3):573-9 - PMID: 10026101 - DOI: 10.1095/biolreprod60.3.573

Jensen LJ, Stuart-Tilley AK, Peters LL, Lux SE, Alper SL, Breton S

Immunolocalization of AE2 anion exchanger in rat and mouse epididymis. Biol Reprod. 1999;61(4):973-80 - PMID: 10491632 - DOI: 10.1095/biolreprod61.4.973

Herak-Kramberger CM, Sabolić I, Blanusa M, Smith PJ, Brown D, Breton S

Cadmium inhibits vacuolar H(+)ATPase-mediated acidification in the rat epididymis. Biol Reprod. 2000;63(2):599-606 - PMID: 10906070 - DOI: 10.1095/biolreprod63.2.599

Herak-Kramberger CM, Breton S, Brown D, Kraus O, Sabolic I

Distribution of the vacuolar H+ atpase along the rat and human male reproductive tract. Biol Reprod. 2001;64(6):1699-707 - PMID: 11369598 - DOI: 10.1095/biolreprod64.6.1699

Pastor-Soler N, Bagnis C, Sabolic I, Tyszkowski R, McKee M, Van Hoek A, Breton S, Brown D

Aquaporin 9 expression along the male reproductive tract. Biol Reprod. 2001;65(2):384-93 - PMID: 11466204 - DOI: 10.1095/biolreprod65.2.384

Fisher JS, Pastor-Soler N, Sharpe RM, Breton S

Modulation of the onset of postnatal development of H(+)-ATPase-rich cells by steroid hormones in rat epididymis. Biol Reprod. 2002;67(4):1106-14 - PMID: 12297525 - DOI: 10.1095/biolreprod67.4.1106

Pastor-Soler N, Isnard-Bagnis C, Herak-Kramberger C, Sabolic I, Van Hoek A, Brown D, Breton S

Expression of aquaporin 9 in the adult rat epididymal epithelium is modulated by androgens. Biol Reprod. 2002;66(6):1716-22 - PMID: 12021052 - DOI: 10.1095/biolreprod66.6.1716

Da Silva N, Silberstein C, Beaulieu V, Pietrement C, Van Hoek AN, Brown D, Breton S

Postnatal expression of aquaporins in epithelial cells of the rat epididymis. Biol Reprod. 2005;74(2):427-38 - PMID: 16221990 - DOI: 10.1095/biolreprod.105.044735

Pietrement C, Sun-Wada GH, Silva ND, McKee M, Marshansky V, Brown D, Futai M, Breton S

Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis. Biol Reprod. 2005;74(1):185-94 - PMID: 16192400 - DOI: 10.1095/biolreprod.105.043752

Schulz RB, Ripoll J, Ntziachristos V

Experimental fluorescence tomography of tissues with noncontact measurements. IEEE T Med Imaging. 2004;23(4):492-500 - PMID: 15084074 - DOI: 10.1109/TMI.2004.825633

Zacharakis G, Ripoll J, Weissleder R, Ntziachristos V.

Fluorescent protein tomography scanner for small animal imaging IEEE T Med Imaging. 2005;24(7):878-85 - PMID: 16011317 - DOI: 10.1109/tmi.2004.843254

Marias K, Ripoll J, Meyer H, Ntziachristos V, Orphanoudakis S.

Image analysis for assessing molecular activity changes in time-dependent geometries IEEE T Med Imaging. 2005;24(7):894-900 - PMID: 16011319 - DOI: 10.1109/tmi.2005.848612

Soubret A, Ripoll J, Ntziachristos V.

Accuracy of fluorescent tomography in the presence of heterogeneities: study of the normalized Born ratio IEEE T Med Imaging. 2005;24(10):1377-86 - PMID: 16229423 - DOI: 10.1109/tmi.2005.857213

Hyde D, Miller E, Brooks DH, Ntziachristos V

A statistical approach to inverting the Born ratio. IEEE T Med Imaging. 2007;26 (7):893-905 - PMID: 17649903 - DOI: 10.1109/TMI.2007.895467

Lasser T, Soubret A, Ripoll J, Ntziachristos V

Surface Reconstruction for free-space 360 degrees fluorescence molecular tomography and the effects of animal motion. IEEE T Med Imaging. 2008;27(2):188-94 - PMID: 18334440 - DOI: 10.1109/TMI.2007.904662

Tang Y, Shah K, Messerli SM, Snyder E, Breakefield X, Weissleder R

In vivo tracking of neural progenitor cell migration to glioblastomas Hum Gene Ther. 2003;14:1247-54 - PMID: 12952596 - DOI: 10.1089/104303403767740786

Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X

Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery. Hum Gene Ther. 2005;16:1367-76 - PMID: 16390268 - DOI: 10.1089/hum.2005.16.1367

Messerli SM, Prabhakar S, Tang Y, Mahmood U, Weissleder R, Bronson R, Martuza R, Rabkin S, Breakefield XO

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2. Hum Gene Ther. 2006;17(1):20-30 - PMID: 16409122 - DOI: 10.1089/hum.2006.17.20

Schellingerhout D, Bogdanov A, Marecos E, Spear M, Breakefield X, Weissleder R

Mapping the in vivo distribution of herpes simplex virions. Hum Gene Ther. 1998;9(11):1543-9 - PMID: 9694153 - DOI: 10.1089/hum.1998.9.11-1543

Rainov NG, Zimmer C, Chase M, Kramm CM, Chiocca EA, Weissleder R, Breakefield XO

Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. Hum Gene Ther. 1995;6(12):1543-52 - PMID: 8664379 - DOI: 10.1089/hum.1995.6.12-1543

Ji H, Wang TL, Chen CH, Pai SI, Hung CF, Lin KY, Kurman RJ, Pardoll DM, Wu TC

Targeting human papillomavirus type 16 E7 to the endosomal/lysosomal compartment enhances the antitumor immunity of DNA vaccines against murine human papillomavirus type 16 E7-expressing tumors. Hum Gene Ther. 1999;10(17):2727-40 - PMID: 10584920 - DOI: 10.1089/10430349950016474

Sabolic I, Herak-Kramberger CM, Antolovic R, Breton S, Brown D

Loss of basolateral invaginations in proximal tubules of cadmium-intoxicated rats is independent of microtubules and clathrin. Toxicology. 2005;218(2-3):149-63 - PMID: 16288946 - DOI: 10.1016/j.tox.2005.10.009

Montet X, Yuan H, Weissleder R, Josephson L

Enzyme-based visualization of receptor-ligand binding in tissues. Lab Invest. 2006;86(5):517-25 - PMID: 16568109 - DOI: 10.1038/labinvest.3700404

Kang HW, Torres D, Wald L, Weissleder R, Bogdanov AA

Targeted imaging of human endothelial-specific marker in a model of adoptive cell transfer. Lab Invest. 2006;86(6):599-609 - PMID: 16607378 - DOI: 10.1038/labinvest.3700421

Lienard D, Rimoldi D, Marchand M, Dietrich P, van Baren N, Geldhof C, Batard P, Guillaume P, Ayyoub M, Pittet M, Zippelius A, Fleischhauer K, Lejeune F, Cerottini J, Romero P, Speiser D

Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA. Cancer Immunol Immunther. 2004;4:4 - PMID: 15149168

Kang HW, Weissleder R, Bogdanov A Jr

Targeting of MPEG-protected polyamino acid carrier to human E-selectin in vitro Amino Acids. 2002;23:301-8 - PMID: 12373551 - DOI: 10.1007/s00726-001-0142-2

Pham W, Lai WF, Weissleder R, Tung CH

High efficiency synthesis of a bioconjugatable near-infrared fluorochrome Bioconjug Chem. 2003;14:1048-51 - PMID: 13129411 - DOI: 10.1021/bc034070h

Moon, WK, Lin Y, O'Loughlin T, Tang Y, Kim DE, Weissleder R, Tung CH

Enhanced tumor detection using a folate receptor-targeted near-infrared fluorochrome conjugate Bioconjug Chem. 2003;14:539-45 - PMID: 12757377 - DOI: 10.1021/bc0340114

Koch AM, Reynolds F, Kircher MF, Merkle HP, Weissleder R, Josephson L

Uptake and metabolism of a dual fluorochrome Tat-nanoparticle in HeLa cells Bioconjug Chem. 2003;14:1115-21 - PMID: 14624624 - DOI: 10.1021/bc034123v

Zhao M, Kircher MF, Josephson L, Weissleder R

Differential conjugation of tat peptide to superparamagnetic nanoparticles and its effect on cellular uptake Bioconjug Chem. 2002;13:840-4 - PMID: 12121140 - DOI: 10.1021/bc0255236

Wunderbaldinger P, Josephson L, Weissleder R

Tat peptide directs enhanced clearance and hepatic permeability of magnetic nanoparticles Bioconjug Chem. 2002;13:264-8 - PMID: 11906263 - DOI: 10.1021/bc015563u

Lin Y, Weissleder R, Tung CH

Novel near-infrared cyanine fluorochromes: synthesis, properties, and bioconjugation Bioconjug Chem. 2002;13:605-10 - PMID: 12009952 - DOI: 10.1021/bc0155723

Kang HW, Josephson L, Petrovsky A, Weissleder R, Bogdanov A Jr

Magnetic resonance imaging of inducible E-selectin expression in human endothelial cell culture Bioconjug Chem. 2002;13:122-7 - PMID: 11792187 - DOI: 10.1021/bc0155521

Josephson L, Kircher MF, Mahmood U, Tang Y, Weissleder R

Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes Bioconjug Chem. 2002;13:554-60 - PMID: 12009946 - DOI: 10.1021/bc015555d

Hogemann D, Ntziachristos V, Josephson L, Weissleder R

High throughput magnetic resonance imaging for evaluating targeted nanoparticle probes Bioconjug Chem. 2002;13:116-21 - PMID: 11792186 - DOI: 10.1021/bc015549h

Weissleder R, Bogdanov A Jr, Tung CH, Weinmann HJ

Size optimization of synthetic graft copolymers for in vivo angiogenesis imaging Bioconjug Chem. 2001;12:213-9 - PMID: 11312682 - DOI: 10.1021/bc000091p

Hogemann D, Josephson L, Weissleder R, Basilion JP

Improvement of MRI probes to allow efficient detection of gene expression Bioconjug Chem. 2000;11:941-6 - PMID: 11087345 - DOI: 10.1021/bc000079x

Bhorade R, Weissleder R, Nakakoshi T, Moore A, Tung CH

Macrocyclic chelators with paramagnetic cations are internalized into mammalian cells via a HIV-tat derived membrane translocation peptide Bioconjug Chem. 2000;11:301-5 - PMID: 10821645 - DOI: 10.1021/bc990168d

Tung CH, Bredow S, Mahmood U, Weissleder R

Preparation of a cathepsin D sensitive near-infrared fluorescence probe for imaging Bioconjug Chem. 1999;10:892-6 - PMID: 10502358 - DOI: 10.1021/bc990052h

Josephson L, Tung CH, Moore A, Weissleder R

High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates Bioconjug Chem. 1999;10:186-91 - PMID: 10077466 - DOI: 10.1021/bc980125h

Kircher MF, Weissleder R, Josephson L

A dual fluorochrome probe for imaging proteases Bioconjug Chem. 2004;15:242-8 - PMID: 15025519 - DOI: 10.1021/bc034151d

Banerjee P, Reichardt W, Weissleder R, Bogdanov A Jr

Novel hyperbranched dendron for gene transfer in vitro and in vivo. Bioconjug Chem. 2004;15(5):960-8 - PMID: 15366948 - DOI: 10.1021/bc0342128

Schellenberger EA, Sosnovik D, Weissleder R, Josephson L

Magneto/Optical annexin v, a multimodal protein. Bioconjug Chem. 2004;15(5):1062-7 - PMID: 15366960 - DOI: 10.1021/bc049905i

Pham W, Choi Y, Weissleder R, Tung CH

Developing a Peptide-Based Near-Infrared Molecular Probe for Protease Sensing. Bioconjug Chem. 2004;15(6):1403-1407 - PMID: 15546208 - DOI: 10.1021/bc049924s

Metelev V, Weissleder R, Bogdanov A Jr

Synthesis and Properties of Fluorescent NF-kappaB-Recognizing Hairpin Oligodeoxyribonucleotide Decoys. Bioconjug Chem. 2004;15(6):1481-1487 - PMID: 15546218 - DOI: 10.1021/bc049916b

Tsourkas A, Shinde-Patil VR, Kelly KA, Patel P, Wolley A, Allport JR, Weissleder R.

In Vivo Imaging of Activated Endothelium Using an Anti-VCAM-1 Magneto optical Probe Bioconjug Chem. 2005;(3):576-581 - PMID: 15898724 - DOI: 10.1021/bc050002e

Yuan H, Luo J, Field S, Weissleder R, Cantley L, Josephson L.

Synthesis and Activity of C11-Modified Wortmannin Probes for P13 Kinase Bioconjug Chem. 2005;(3):669-675 - PMID: 15898736 - DOI: 10.1021/bc049714f

Reynolds F, Weissleder R, Josephson L.

Protamine as an efficient membrane-translocating Peptide Bioconjug Chem. 2005;16(5):1240-5 - PMID: 16173804 - DOI: 10.1021/bc0501451

Hilderbrand SA, Kelly KA, Weissleder R, Tung CH.

Monofunctional near-infrared fluorochromes for imaging applications Bioconjug Chem. 2005;16(5):1275-81 - PMID: 16173808 - DOI: 10.1021/bc0501799

Sun EY, Josephson L, Kelly KA, Weissleder R

Development of nanoparticle libraries for biosensing. Bioconjug Chem. 2006;17(1):109-13 - PMID: 16417258 - DOI: 10.1021/bc050290e

Banerjee P, Weissleder R, Bogdanov A

Linear Polyethyleneimine Grafted to a Hyperbranched Poly(ethylene glycol)-like Core: A Copolymer for Gene Delivery. Bioconjug Chem. 2006;17(1):125-31 - PMID: 16417260 - DOI: 10.1021/bc050083e

Galande A, Weissleder R, Tung CH.

Fluorescence Probe with a pH-Sensitive Trigger Bioconjug Chem. 2006;17 (2):255-257 - PMID: 16536452 - DOI: 10.1021/bc050330e

Montet X, Weissleder R, Josephson L.

Imaging pancreatic cancer with a peptide-nanoparticle conjugate targeted to normal pancreas Bioconjug Chem. 2006;17(4):905-911 - PMID: 16848396 - DOI: 10.1021/bc060035+

Lai KS, Ho NH, Cheng JD, Tung CH

Selective Fluorescence Probes for Dipeptidyl Peptidase Activity-Fibroblast Activation Protein and Dipeptidyl Peptidase IV. Bioconjug Chem. 2007;18(4):1246-50 - PMID: 17489551 - PMCID: PMC2562575 - DOI: 10.1021/bc0603586

Kim GY, Josephson L, Langer R, Cima MJ

Magnetic Relaxation Switch Detection of Human Chorionic Gonadotrophin. Bioconjug Chem. 2007;18(6):2024-8 - PMID: 17892270 - DOI: 10.1021/bc070110w

Law B, Weissleder R, Tung CH

Protease-Sensitive Fluorescent Nanofibers. Bioconjug Chem. 2007;(18) 6 ::1701-1704 - PMID: 17915958 - PMCID: PMC2528070 - DOI: 10.1021/bc070054z

Barnes KR, Blois J, Smith A, Yuan H, Reynolds F, Weissleder R, Cantley LC, Josephson L

Fate of a Bioactive Fluorescent Wortmannin Derivative in Cells. Bioconjug Chem. 2007;19:130-137 - PMID: 17988080 - DOI: 10.1021/bc7002204

Hilderbrand SA, Kelly KA, Niedre M, Weissleder R

Near Infrared Fluorescence-Based Bacteriophage Particles for Ratiometric pH Imaging. Bioconjug Chem. 2008;19(8):1635-9 - PMID: 18666791 - PMCID: PMC2705288 - DOI: 10.1021/bc800188p

Shao F, Weissleder R, Hilderbrand SA

Monofunctional Carbocyanine Dyes for Bio- and Bioorthogonal Conjugation. Bioconjug Chem. 2008;19(12): :2487-2491 - PMID: 19053316 - PMCID: PMC2656649 - DOI: 10.1021/bc800417b

Devaraj N, Weissleder R, Hilderbrand S

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging. Bioconjug Chem. 2008;19(12):2297-2299 - PMID: 19053305 - PMCID: PMC2677645 - DOI: 10.1021/bc8004446

Marecos E, Weissleder R, Bogdanov A

Antibody-mediated versus nontargeted delivery in a human small cell lung carcinoma model. Bioconjug Chem. 1998;9(2):184-91 - PMID: 9548533 - DOI: 10.1021/bc970146w

Shen TT, Bogdanov A, Bogdanova A, Poss K, Brady TJ, Weissleder R

Magnetically labeled secretin retains receptor affinity to pancreas acinar cells. Bioconjug Chem. 1996;7(3):311-6 - PMID: 8816953 - DOI: 10.1021/bc960003u

Bogdanov AA, Martin C, Bogdanova AV, Brady TJ, Weissleder R

An adduct of cis-diamminedichloroplatinum(II) and poly(ethylene glycol)poly(L-lysine)-succinate: synthesis and cytotoxic properties. Bioconjug Chem. 1996;7(1):144-9 - PMID: 8742003 - DOI: 10.1021/bc950089b

Yoshida S, Kurokohchi K, Ueno T, Yoshino M, Shimada M, Masaki T

Hepatic von Meyenburg complex: a trigger of severe portal hypertension. Liver Int. 2008;29(4):614-5 - PMID: 19018981 - PMCID: PMC2711260 - DOI: 10.1111/j.1478-3231.2008.01903.x

Shah K, Weissleder R

Molecular Optical Imaging: Applications Leading to the Development of Present Day Therapeutics NeuroRx. 2005;2:215-225 - PMID: 15897946 - PMCID: PMC1064987 - DOI: 10.1602/neurorx.2.2.215

Brown D, Hasler U, Nunes P, Bouley R, Lu H

Phosphorylation events and the modulation of aquaporin 2 cell surface expression. Curr Opin Nephrol Hypertens. 2008;17(5):491-8 - PMID: 18695390 - PMCID: PMC3774073 - DOI: 10.1097/MNH.0b013e3283094eb1

Marshansky V, Ausiello DA, Brown D

Physiological importance of endosomal acidification: potential role in proximal tubulopathies. Curr Opin Nephrol Hypertens. 2002;11(5):527-37 - PMID: 12187318 - DOI: 10.1097/00041552-200209000-00009

Huang X, Li Y, Im H, Yarimaga O, Kim J, Jang D, Cho S, Cai W, Choi Y

Morphology-controlled SWCNT/polymeric microsphere arrays by a wet chemical self-assembly technique and their application for sensors Nanotechnology. 2006;17(12):2988

Kozloff KM, Quinti L, Patntirapong S, Hauschka PV, Tung CH, Weissleder R, Mahmood U

Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo. Bone. 2008;44:190-198 - PMID: 19007918 - PMCID: PMC2656637 - DOI: 10.1016/j.bone.2008.10.036

Wunderbaldinger P, Josephson L, Weissleder R

Crosslinked iron oxides (CLIO): a new platform for the development of targeted MR contrast agents Acad Radiol. 2002;9 Suppl 2:S304-6 - PMID: 12188255 - DOI: 10.1016/s1076-6332(03)80210-6

Schellenberger EA, Hogemann D, Josephson L, Weissleder R

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Acad Radiol. 2002;9 Suppl 2:S310-1 - PMID: 12188257 - DOI: 10.1016/s1076-6332(03)80212-x

Ntziachristos, V, Bremer C, Tung C, Weissleder R

Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT) Acad Radiol. 2002;9 Suppl 2:S323-5 - PMID: 12188262 - DOI: 10.1016/s1076-6332(03)80217-9

Mahmood U, Weissleder R

Some tools for molecular imaging Acad Radiol. 2002;9:629-31 - PMID: 12061735 - DOI: 10.1016/s1076-6332(03)80306-9

Harisinghani MG, Barentsz JO, Hahn PF, Deserno W, de la Rosette J, Saini S, Marten K, Weissleder R

MR lymphangiography for detection of minimal nodal disease in patients with prostate cancer Acad Radiol. 2002;9 Suppl 2:S312-3 - PMID: 12188258 - DOI: 10.1016/s1076-6332(03)80213-1

Bremer C, Tung CH, Weissleder R

Molecular imaging of MMP expression and therapeutic MMP inhibition Acad Radiol. 2002;9 Suppl 2:S314-5 - PMID: 12188259 - DOI: 10.1016/s1076-6332(03)80214-3

Wagenaar DJ, Weissleder R, Hengerer A

Glossary of molecular imaging terminology Acad Radiol. 2001;8:409-20 - PMID: 11345272 - DOI: 10.1016/S1076-6332(03)80549-4

Bremer C, Weissleder R

In vivo imaging of gene expression Acad Radiol. 2001;8:15-23 - PMID: 11201452 - DOI: 10.1016/s1076-6332(03)80739-0

Harisinghani MG, Saini S, Hahn PF, Weissleder R, Mueller PR

MR imaging of lymph nodes in patients with primary abdominal and pelvic malignancies using ultrasmall superparamagnetic iron oxide (Combidex). Acad Radiol. 1998;5 Suppl 1:S167-9, discussion S183-4 - PMID: 9561072 - DOI: 10.1016/s1076-6332(98)80095-0

Lesuffleur A, Im H, Lindquist NC, Oh S

Periodic nanohole arrays with shape-enhanced plasmon resonance as real-time biosensors Appl Phys Lett. 2007;90:243110

Vinegoni C, Ralston T, Tan W, Luo W, Marks DL, Boppart SA

Integrated structural and functional imaging combining spectral-domain optical coherence and multiphoton microscopy Appl Phys Lett. 2006;88:051105

Marks DL, Vinegoni C, Bredfeldt JS, Boppart SA

Interferometric differentiation between resonant Coherent Anti-Stokes Raman Scattering and nonresonant four-wave-mixing processes Appl Phys Lett. 2004;85:5787-89

Pellegrini V, Colombelli R, Vinegoni C, Rubini S, Lantier R, Franciosi A, Beltram F, Pavesi L

Second harmonic generation in ZnSe microcavity. Appl. Phys. Lett. 1999;74:1945-47 Appl Phys Lett. 1999;74:1945-47

Cazzanelli M, Cole D, Donegan JF, Lunney JG, Middleton PG, O'Donnell KP, Vinegoni C, Pavesi L

Photoluminescence of localized excitons in pulsed laser deposited GaN Appl Phys Lett. 1998;73:3390-2

Hooper B, Domankevitz Y, Anderson R, Lin CP

Optical temperature probe Appl Phys Lett. 2001;78:2381-3

Lin CP, Kelly MW

Cavitation and acoustic emission around laser-heated microparticles Appl Phys Lett. 1998;72:2800

Hunt TP, Lee H, and Westervelt RM

Addressable micropost array for the dielectrophoretic manipulation of particles in fluid Appl Phys Lett. 0;85(26):6421-23

Lee H, Purdon AM, Westervelt RM

Manipulation of biological cells using a microelectromagnet matrix Appl Phys Lett. 0;85(6):1063-65

Taktak S, Weissleder R, Josephson L

Electrode Chemistry Yields a Nanoparticle-Based NMR Sensor for Calcium. Langmuir. 2008;24 (14):7596-7598 - PMID: 18558729 - PMCID: PMC2748273 - DOI: 10.1021/la8006298

Huang XJ, Ryu SW, Im HS, Choi YK

Wet chemical needlelike assemblies of single-walled carbon nanotubes on a silicon surface. Langmuir. 2007;23(3):991-4 - PMID: 17241002 - DOI: 10.1021/la063144l

Smith RN, Ueno T, Ito T, Tanaka K, Shea SP, Abdi R

Chemokines and chronic heart allograft rejection. Transplantation. 2007;84(3):442-4 - PMID: 17700176 - DOI: 10.1097/01.tp.0000277535.02541.30

Tremblay J, Chen H, Peng J, Kunes J, Vu MD, Der Sarkissian S, deBlois D, Bolton AE, Gaboury L, Marshansky V, Gouadon E, Hamet P

Renal ischemia-reperfusion injury in the rat is prevented by a novel immune modulation therapy. Transplantation. 2002;74(10):1425-33 - PMID: 12451244 - DOI: 10.1097/00007890-200211270-00015

Ansari MJ, Fiorina P, Dada S, Guleria I, Ueno T, Yuan X, Trikudanathan S, Smith RN, Freeman G, Sayegh MH

Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. Clin Immunol. 2007;126(2):140-7 - PMID: 17889619 - DOI: 10.1016/j.clim.2007.07.019

Pirri P, Vinegoni C, Pavesi L

Optical and photoluminescence properties of a-Si(1-x)Nx:H films deposited by PECVD Phys Rev B. 2000;61:4693-8

Giorgis F, Pirri CF, Vinegoni C, Pavesi L

Luminescence processes in amorphous silicon-nitride nanometric multilayers Phys Rev B. 1999;60:11572-76

Nahrendorf M, Weissleder R, Ertl G

Does FXIII Deficiency Impair Wound Healing after Myocardial Infarction? PLoS ONE. 2006;1:e48 - PMID: 17183677 - PMCID: PMC1762326 - DOI: 10.1371/journal.pone.0000048

Kelly KA, Carson J, McCarthy JR, Weissleder R

Novel Peptide Sequence ("IQ-tag") with High Affinity for NIR Fluorochromes Allows Protein and Cell Specific Labeling for In Vivo Imaging. PLoS ONE. 2007;2:e665 - PMID: 17653285 - PMCID: PMC1919420 - DOI: 10.1371/journal.pone.0000665

Swirski FK, Berger CR, Figueiredo JL, Mempel TR, von Andrian UH, Pittet MJ, Weissleder R

A near-infrared cell tracker reagent for multiscopic in vivo imaging and quantification of leukocyte immune responses. PLoS ONE. 2007;2(10):e1075 - PMID: 17957257 - PMCID: PMC2034600 - DOI: 10.1371/journal.pone.0001075

Gounaris E, Tung CH, Restaino C, Maehr R, Kohler R, Joyce JA, Plough HL, Barrett TA, Weissleder R, Khazaie K

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth. PLoS ONE. 2008;3:e2916 - PMID: 18698347 - PMCID: PMC2488397 - DOI: 10.1371/journal.pone.0002916

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A Highly Sensitive Assay for Monitoring the Secretory Pathway and ER Stress PLoS ONE. 0;6:e571

Jeong JH, Wang Z, Guimaraes AS, Ouyang X, Figueiredo JL, Ding Z, Jiang S, Guney I, Kang GH, Shin E, Hahn WC, Loda MF, Abate-Shen C, Weissleder R, Chin L

BRAF activation initiates but does not maintain invasive prostate adenocarcinoma. PLoS ONE. 2008;3(12):e3949 - PMID: 19079609 - PMCID: PMC2597248 - DOI: 10.1371/journal.pone.0003949

Da Silva N, Shum WW, El-Annan J, Paunescu TG, McKee M, Smith PJ, Brown D, Breton S

Relocalization of the V-ATPase B2 subunit to the apical membrane of epididymal clear cells of mice deficient in the B1 subunit. Am J Physiol Cell Physiol. 2007;293(1):C199-210 - PMID: 17392376 - DOI: 10.1152/ajpcell.00596.2006

Pastor-Soler NM, Hallows KR, Smolak C, Gong F, Brown D, Breton S

Alkaline pH- and cAMP-induced V-ATPase membrane accumulation is mediated by protein kinase A in epididymal clear cells. Am J Physiol Cell Physiol. 2008;294:C488-94 - PMID: 18160485 - PMCID: PMC4303256 - DOI: 10.1152/ajpcell.00537.2007

Roelen B, Cohen O, Raychowdhury M, Chadee D, Zhang Y, Kyriakis J, Alessandrini A, Lin H

Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation. Am J Physiol Cell Physiol. 2003;285(4):C823-30 - PMID: 12801888 - DOI: 10.1152/ajpcell.00053.2003

Paunescu TG, Jones AC, Tyszkowski R, Brown D

V-ATPase expression in the mouse olfactory epithelium. Am J Physiol Cell Physiol. 2008;295(4):C923-30 - PMID: 18667600 - PMCID: PMC2575830 - DOI: 10.1152/ajpcell.00237.2008

Nunes P, Hasler U, McKee M, Lu HA, Bouley R, Brown D

A fluorimetry-based ssYFP secretion assay to monitor vasopressin-induced exocytosis in LLC-PK1 cells expressing aquaporin-2 (AQP2). Am J Physiol Cell Physiol. 2008;295(6):C1476-87 - PMID: 18799651 - PMCID: PMC2603565 - DOI: 10.1152/ajpcell.00344.2008

Miller RL, Zhang P, Smith M, Beaulieu V, Paunescu TG, Brown D, Breton S, Nelson RD

V-ATPase B1-subunit promoter drives expression of EGFP in intercalated cells of kidney, clear cells of epididymis and airway cells of lung in transgenic mice. Am J Physiol Cell Physiol. 2005;288(5):C1134-44 - PMID: 15634743 - DOI: 10.1152/ajpcell.00084.2004

Paunescu TG, Da Silva N, Marshansky V, McKee M, Breton S, Brown D

Expression of the 56-kDa B2 subunit isoform of the vacuolar H(+)-ATPase in proton-secreting cells of the kidney and epididymis. Am J Physiol Cell Physiol. 2004;287(1):C149-62 - PMID: 15013950 - DOI: 10.1152/ajpcell.00464.2003

Paunescu TG, Blazer-Yost BL, Vlahos CJ, Helman SI

LY-294002-inhibitable PI 3-kinase and regulation of baseline rates of Na(+) transport in A6 epithelia. Am J Physiol Cell Physiol. 2000;279(1):C236-47 - PMID: 10898735 - DOI: 10.1152/ajpcell.2000.279.1.C236

Stevens AL, Breton S, Gustafson CE, Bouley R, Nelson RD, Kohan DE, Brown D

Aquaporin 2 is a vasopressin-independent, constitutive apical membrane protein in rat vas deferens. Am J Physiol Cell Physiol. 2000;278(4):C791-802 - PMID: 10751327 - DOI: 10.1152/ajpcell.2000.278.4.C791

Isnard-Bagnis C, Da Silva N, Beaulieu V, Yu AS, Brown D, Breton S

Detection of ClC-3 and ClC-5 in epididymal epithelium: immunofluorescence and RT-PCR after LCM. Am J Physiol Cell Physiol. 2003;284(1):C220-32 - PMID: 12475763 - DOI: 10.1152/ajpcell.00374.2001

El-Annan J, Brown D, Breton S, Bourgoin S, Ausiello DA, Marshansky V

Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ. Am J Physiol Cell Physiol. 2003;286(4):C768-78 - PMID: 14684384 - DOI: 10.1152/ajpcell.00250.2003

Bouley R, Lin HY, Raychowdhury MK, Marshansky V, Brown D, Ausiello DA

Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway. Am J Physiol Cell Physiol. 2005;288(6):C1390-401 - PMID: 15677378 - DOI: 10.1152/ajpcell.00353.2004

Lisi S, Botta R, Pinchera A, Collins AB, Refetoff S, Arvan P, Bu G, Grasso L, Marshansky V, Bechoua S, Hurtado-Lorenzo A, Marcocci C, Brown D, McCluskey RT, Marinò M

Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice. Am J Physiol Cell Physiol. 2005;290(4):C1160-7 - PMID: 16306127 - DOI: 10.1152/ajpcell.00382.2005

Zuk A, Bonventre JV, Brown D, Matlin KS

Polarity, integrin, and extracellular matrix dynamics in the postischemic rat kidney. Am J Physiol Cell Physiol. 1998;275(3):C711-C731 - PMID: 29585718 - DOI: 10.1152/ajpcell.1998.275.3.C711

Breton S, Hammar K, Smith PJS, Brown D

Proton secretion in the male reproductive tract: involvement of Cl--independent HCO 3 - transport. Am J Physiol Cell Physiol. 1998;275(4):C1134-C1142 - PMID: 29585324 - DOI: 10.1152/ajpcell.1998.275.4.C1134

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Paunescu TG, Helman SI

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Hink M, Shah K, Russinova E, de Vries S, Visser A

Fluorescence Fluctuation Analysis of AtSERK and BRI1 Oligomerization. Biophys J. 2007;94(3):1052-62 - PMID: 17905839 - PMCID: PMC2186235 - DOI: 10.1529/biophysj.107.112003

Pitsillides C, Joe E, Wei X, Anderson R, Lin C

Selective cell targeting with light-absorbing microparticles and nanoparticles. Biophys J. 2003;84:4023-32 - PMID: 12770906 - PMCID: PMC1302982 - DOI: 10.1016/S0006-3495(03)75128-5

Figueiredo JL, Passerotti CC, Sponholtz T, Nguyen HT, Weissleder R

A Novel Method of Imaging Calcium Urolithiasis Using Fluorescence. J Urolology. 2008;179:1610-1614 - PMID: 18295253 - DOI: 10.1016/j.juro.2007.11.100

Yip S, Aboody KS, Burns M, Imitola J, Boockvar JA, Allport J, Park KI, Teng YD, Lachyankar M, McIntosh T, O'Rourke DM, Khoury S, Weissleder R, Black PM, Weiss W, Snyder EY

Neural stem cell biology may be well suited for improving brain tumor therapies Cancer J. 2003;9:189-204 - PMID: 12952304 - DOI: 10.1097/00130404-200305000-00007

Funovics M, Weissleder R, Tung CH

Protease sensors for bioimaging Anal Bioanal Chem. 2003;377:956-63 - PMID: 12955390 - DOI: 10.1007/s00216-003-2199-0

Reynolds F, O'loughlin T, Weissleder R, Josephson L.

Method of Determining Nanoparticle Core Weight Anal Bioanal Chem. 2005;77(3):814-817 - PMID: 15679348 - DOI: 10.1021/ac049307x

Feldman AS, McDougal WS, Harisinghani MG

The potential of nanoparticle-enhanced imaging. Urol Oncol. 2008;26(1):65-73 - PMID: 18190834 - DOI: 10.1016/j.urolonc.2007.03.016

Huebert D, Kamal M, O'Donovan A, Bernstein B

Genome-wide analysis of histone modifications by ChIP-on-chip. Methods. 2006;40(4):365-9 - PMID: 17101450 - DOI: 10.1016/j.ymeth.2006.07.032

Nahrendorf M, Badea C, Hedlund LW, Figueiredo JL, Sosnovik DE, Johnson GA, Weissleder R

High Resolution Imaging of Murine Myocardial Infarction With Delayed Enhancement Cine Micro-CT. Am J Physiol-Heart C. 2007;292(6):3172-8 - PMID: 17322414 - PMCID: PMC2680216 - DOI: 10.1152/ajpheart.01307.2006

Nahrendorf M, Streif J, Hiller K, Hu K, Nordbeck P, Ritter O, Sosnovik D, Bauer L, Neubauer S, Jakob P, Ertl G, Spindler M, Bauer W

Multimodal functional cardiac MRI in creatine kinase-deficient mice reveals subtle abnormalities in myocardial perfusion and mechanics. Am J Physiol-Heart C. 2006;290(6):H2516-21 - PMID: 16415075 - DOI: 10.1152/ajpheart.01038.2005

Nahrendorf M, Hiller K, Greiser A, Kohler S, Neuberger T, Hu K, Waller C, Albrecht M, Neubauer S, Haase A, Ertl G, Bauer W

Chronic coronary artery stenosis induces impaired function of remote myocardium: MRI and spectroscopy study in rat. Am J Physiol-Heart C. 2003;285(6):H2712-21 - PMID: 12933339 - DOI: 10.1152/ajpheart.00233.2003

Nahrendorf M, Hu K, Fraccarollo D, Hiller K, Haase A, Bauer W, Ertl G

Time course of right ventricular remodeling in rats with experimental myocardial infarction. Am J Physiol-Heart C. 2003;284(1):H241-8 - PMID: 12388245 - DOI: 10.1152/ajpheart.00537.2002

Bouley R, Pastor-Soler N, Cohen O, McLaughlin M, Breton S, Brown D

Stimulation of AQP2 membrane insertion in renal epithelial cells in vitro and in vivo by the cGMP phosphodiesterase inhibitor sildenafil citrate (Viagra). Am J Physiol Renal Physiol. 2005;288(6):F1103-12 - PMID: 15644488 - DOI: 10.1152/ajprenal.00337.2004

Yi X, Bouley R, Lin HY, Bechoua S, Sun TX, Del Re E, Shioda T, Raychowdhury MK, Lu HA, Abou-Samra AB, Brown D, Ausiello DA

Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R. Am J Physiol Renal Physiol. 2007;292(5):F1303-13 - PMID: 17287200 - DOI: 10.1152/ajprenal.00441.2005

Paunescu TG, Da Silva N, Russo LM, McKee M, Lu HA, Breton S, Brown D

Association Of Soluble Adenylyl Cyclase (sAC) With The V-ATPase In Renal Epithelial Cells. Am J Physiol Renal Physiol. 2007;294(1):F130-8 - PMID: 17959750 - DOI: 10.1152/ajprenal.00406.2007

Paunescu TG, Russo LM, Da Silva N, Kovacikova J, Mohebbi N, Van Hoek AN, McKee M, Wagner CA, Breton S, Brown D

Compensatory membrane expression of the V-ATPase B2 subunit isoform in renal medullary intercalated cells of B1-deficient mice. Am J Physiol Renal Physiol. 2007;293(6):F1915-26 - PMID: 17898041 - DOI: 10.1152/ajprenal.00160.2007

Lu HA, Matsuzaki T, Bouley R, Hasler U, Qin Q, Brown D

The phosphorylation state of serine 256 is dominant over that of serine 261 in the regulation of AQP2 trafficking in renal epithelial cells. Am J Physiol Renal Physiol. 2008;295(1):F290-4 - PMID: 18434387 - PMCID: PMC2494506 - DOI: 10.1152/ajprenal.00072.2008

Breton S, Nsumu NN, Galli T, Sabolic I, Smith PJ, Brown D

Tetanus toxin-mediated cleavage of cellubrevin inhibits proton secretion in the male reproductive tract. Am J Physiol Renal Physiol. 2000;278(5):F717-25 - PMID: 10807583 - DOI: 10.1152/ajprenal.2000.278.5.F717

Silver RB, Breton S, Brown D

Potassium depletion increases proton pump (H(+)-ATPase) activity in intercalated cells of cortical collecting duct. Am J Physiol Renal Physiol. 2000;279(1):F195-202 - PMID: 10894802 - DOI: 10.1152/ajprenal.2000.279.1.F195

Bagnis C, Marshansky V, Breton S, Brown D

Remodeling the cellular profile of collecting ducts by chronic carbonic anhydrase inhibition. Am J Physiol Renal Physiol. 2001;280(3):F437-48 - PMID: 11181405 - DOI: 10.1152/ajprenal.2001.280.3.F437

Bagnis C, Marsolais M, Biemesderfer D, Laprade R, Breton S

Na+/H+-exchange activity and immunolocalization of NHE3 in rat epididymis. Am J Physiol Renal Physiol. 2001;280(3):F426-36 - PMID: 11181404 - DOI: 10.1152/ajprenal.2001.280.3.F426

Breton S, Inoue T, Knepper MA, Brown D

Antigen retrieval reveals widespread basolateral expression of syntaxin 3 in renal epithelia. Am J Physiol Renal Physiol. 2002;282(3):F523-9 - PMID: 11832435 - DOI: 10.1152/ajprenal.00128.2001

Zharkikh L, Zhu X, Stricklett PK, Kohan DE, Chipman G, Breton S, Brown D, Nelson RD

Renal principal cell-specific expression of green fluorescent protein in transgenic mice. Am J Physiol Renal Physiol. 2002;283(6):F1351-64 - PMID: 12426236 - DOI: 10.1152/ajprenal.0224.2001

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New insights into the regulation of V-ATPase-dependent proton secretion. Am J Physiol Renal Physiol. 2006;292(1):F1-10 - PMID: 17032935 - DOI: 10.1152/ajprenal.00340.2006

Lu H, Sun TX, Bouley R, Blackburn K, McLaughlin M, Brown D

Inhibition of endocytosis causes phosphorylation (S256)-independent plasma membrane accumulation of AQP2. Am J Physiol Renal Physiol. 2003;286(2):F233-43 - PMID: 14519593 - DOI: 10.1152/ajprenal.00179.2003

Alper SL, Stuart-Tilley AK, Biemesderfer D, Shmukler BE, Brown D

Immunolocalization of AE2 anion exchanger in rat kidney. Am J Physiol Renal Physiol. 1997;273(4):F601-F614 - PMID: 29587100 - DOI: 10.1152/ajprenal.1997.273.4.F601

Shayakul C, Kanai Y, Lee WS, Brown D, Rothstein JD, Hediger MA

Localization of the high-affinity glutamate transporter EAAC1 in rat kidney. Am J Physiol Renal Physiol. 1997;273(6):F1023-F1029 - PMID: 29586122 - DOI: 10.1152/ajprenal.1997.273.6.F1023

Kawachi H, Kurihara H, Topham PS, Brown D, Shia MA, Orikasa M, Shimizu F, Salant DJ

Slit diaphragm-reactive nephritogenic MAb 5-1-6 alters expression of ZO-1 in rat podocytes. Am J Physiol Renal Physiol. 1997;273(6):F984-F993 - PMID: 29586119 - DOI: 10.1152/ajprenal.1997.273.6.F984

Brown D, Lee R, Bonventre JV

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Blazer-Yost BL, Paunescu TG, Helman SI, Lee KD, Vlahos CJ

Phosphoinositide 3-kinase is required for aldosterone-regulated sodium reabsorption. Am J Physiol. 1999;277(3 Pt 1):C531-6 - PMID: 10484339 - DOI: 10.1152/ajpcell.1999.277.3.C531

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Beck JS, Breton S, Mairb

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Beck JS, Breton S, Giebisch G, Laprade R

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Breton S, Beck JS, Cardinal J, Giebisch G, Laprade R

Involvement and source of calcium in volume regulatory decrease of collapsed proximal convoluted tubule. Am J Physiol. 1992;263(4 Pt 2):F656-64 - PMID: 1415737 - DOI: 10.1152/ajprenal.1992.263.4.F656

Macri P, Breton S, Beck JS, Cardinal J, Laprade R

Basolateral K+, Cl-, and HCO3- conductances and cell volume regulation in rabbit PCT. Am J Physiol. 1993;264(2 Pt 2):F365-76 - PMID: 8447445 - DOI: 10.1152/ajprenal.1993.264.2.F365

Breton S, Beck JS, Laprade R

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Breton S, Alper SL, Gluck SL, Sly WS, Barker JE, Brown D

Depletion of intercalated cells from collecting ducts of carbonic anhydrase II-deficient (CAR2 null) mice. Am J Physiol. 1995;269(6 Pt 2):F761-74 - PMID: 8594870 - DOI: 10.1152/ajprenal.1995.269.6.F761

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Hypotonicity increases basolateral taurine permeability in rabbit proximal convoluted tubule. Am J Physiol. 1995;268(4 Pt 2):F595-603 - PMID: 7733316 - DOI: 10.1152/ajprenal.1995.268.4.F595

Breton S, Belachgar F, Marsolais M, Lapointe JY, Laprade R

Inhibition of basolateral potassium conductance by taurine in the proximal convoluted tubule. Am J Physiol. 1996;271(5 Pt 2):F1012-9 - PMID: 8945995 - DOI: 10.1152/ajprenal.1996.271.5.F1012

Breton S, Hammar K, Smith PJ, Brown D

Proton secretion in the male reproductive tract: involvement of Cl--independent HCO-3 transport. Am J Physiol. 1998;275(4 Pt 1):C1134-42 - PMID: 9755067 - DOI: 10.1152/ajpcell.1998.275.4.C1134

Emma F, Breton S, Morrison R, Wright S, Strange K

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Montet X, Rajopadhye M, Weissleder R.

An albumin-activated far-red fluorochrome for in vivo imaging ChemMedChem. 2006;1(1):66-69 - PMID: 16892337 - DOI: 10.1002/cmdc.200500028

Choi YD, McCarthy J, Weissleder R, Tung CH

Conjugation of a Photosensitizer to an Oligoarginine-based Cell-penetrating Peptide Increases the Efficacy of Photodynamic Therapy ChemMedChem. 2006;1(4):458-463 - PMID: 16892381 - DOI: 10.1002/cmdc.200500036

Choi Y, Weissleder R, Tung CH

Protease-mediated phototoxicity of a polylysine-chlorin(E6) conjugate. ChemMedChem. 2006;1:698-701 - PMID: 16902920 - DOI: 10.1002/cmdc.200600053

McCarthy JR, Weissleder R

Model Systems for Fluorescence and Singlet Oxygen Quenching by Metalloporphyrins. ChemMedChem. 2007;2:360-365 - PMID: 17245681 - DOI: 10.1002/cmdc.200600244

McCarthy JR, Hyland MA, Bruckner C.

Synthesis of indaphyrins: meso-tetraarylsecochlorin-based porphyrinoids containing direct o-phenyl-to-beta-linkages. Org Biomol Chem. 2004;2(10):1484-91

Mazitschek R, Huwe A, Giannis A

Synthesis and biological evaluation of novel fumagillin and ovalicin analogues. Org Biomol Chem. 2005;3(11):2150-4 - PMID: 15917904 - DOI: 10.1039/b503163j

Reimer P, Bader A, Weissleder R

Application of a stable cell culture assay for the functional assessment of novel MR contrast agents. Eur Radiol. 1997;7(4):527-31 - PMID: 9204333 - DOI: 10.1007/s003300050197

Lesuffleur A, Im H, Lindquist NC, Lim KS, Oh SH

Laser-illuminated nanohole arrays for multiplex plasmonic microarray sensing. Opt Express. 2008;16(1):219-24 - PMID: 18521151 - DOI: 10.1364/oe.16.000219

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Epi-illumination through the microscope objective applied to darkfield imaging and microspectroscopy of nanoparticle interaction with cells in culture. Opt Express. 2006;14(14):6535-42 - PMID: 19516830 - DOI: 10.1364/oe.14.006535

Salthouse C, Hilderbrand S, Weissleder R, Mahmood U

Design and demonstration of a small-animal up-conversion imager. Opt Express. 2008;16 (26):21731-7 - PMID: 19104605 - PMCID: PMC2717740 - DOI: 10.1364/oe.16.021731

Vinegoni C, Bredfeldt J, Marks D, Boppart S

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Lee H, Alt C, Pitsillides CM, Puoris'haag M, Lin CP

In vivo imaging flow cytometer. Opt Express. 2006;14:7789-800 - PMID: 19529148 - PMCID: PMC2801598 - DOI: 10.1364/oe.14.007789

Romero P, Pittet M, Dutoit V, Zippelius A, Lienard D, Lejeune F, Guillaume P, Rimoldi D, Valmori D, Speiser D, Cerottini J

Therapeutic cancer vaccines based on molecularly defined human tumor antigens. Vaccine. 2002;20(4):2-7 - PMID: 12477422 - DOI: 10.1016/s0264-410x(02)00380-8

Bouley R, Hawthorn G, Russo L, Lin H, Ausiello D, Brown D

Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment. Biol Cell. 2006;98(4):215-32 - PMID: 16563128 - DOI: 10.1042/BC20040054

Haller JL, Hyde D, Deliolanis N, de Kleine R, Niedre M, Ntziachristos V

Visualization of Pulmonary Inflammation Using Non-invasive Fluorescence Molecular Imaging. J Appl Physiol. 2008;104(3):795-802 - PMID: 18202169 - DOI: 10.1152/japplphysiol.00959.2007

Cazzanelli M, Vinegoni C, Pavesi L

Temperature dependence of the photo luminescence of all porous silicon microcavities. J. Appl. Phys. 1999;85;1760-4 J Appl Physiol. 1999;85:1760-4

Speiser D, Pittet M, Guillaume P, Lubenow N, Hoffman E, Cerottini J, Romero P

Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring. J Immunother. 2004;27:298-308 - PMID: 15235391 - DOI: 10.1097/00002371-200407000-00006

Farrar CT, Dai G, Novikov M, Rosenzweig A, Weissleder R, Rosen BR, Sosnovik DE

Impact of field strength and iron oxide nanoparticle concentration on the linearity and diagnostic accuracy of off-resonance imaging. NMR Biomed. 2008;21(5):453-63 - PMID: 17918777 - PMCID: PMC2629945 - DOI: 10.1002/nbm.1209

Framme C, Alt C, Schnell S, Sherwood M, Brinkmann R, Lin CP

Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam. Invest Ophth Vis Sci. 2007;48:1782-92 - PMID: 17389512 - DOI: 10.1167/iovs.06-0797

Wei X, Runnels J, Lin C

Selective uptake of indocyanine green by reticulocytes in circulation. Invest Ophth Vis Sci. 2003;44:4489-96 - PMID: 14507897 - PMCID: PMC2830078 - DOI: 10.1167/iovs.03-0041

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Stem-cell based therapies for brain tumors. Curr Opin Mol Ther. 2008;10:334-42 - PMID: 18683097

Montes M, Rufer N, Appay V, Reynard S, Pittet M, Speiser D, Guillaume P, Cerottini J, Romero P, Leyvraz S

Optimum in vitro expansion of human antigen-specific CD8 T cells for adoptive transfer therapy. Clin Exp Immunol. 2005;142:292-302 - PMID: 16232216 - PMCID: PMC1809512 - DOI: 10.1111/j.1365-2249.2005.02914.x

Ritz S, Cundall M, Gajewska B, Swirski F, Wiley R, Alvarez D, Coyle A, Stampfli M, Jordana M

The lung cytokine microenvironment influences molecular events in the lymph nodes during Th1 and Th2 respiratory mucosal sensitization to antigen in vivo. Clin Exp Immunol. 2004;138(2):213-20 - PMID: 15498029 - PMCID: PMC1809215 - DOI: 10.1111/j.1365-2249.2004.02618.x

Moffat BA, Reddy GR, McConville P, Hall DE, Chenevert TL, Kopelman RR, Philbert M, Weissleder R, Rehemtulla A, Ross BD

A novel polyacrylamide magnetic nanoparticle contrast agent for molecular imaging using MRI Mol Imaging. 2003;2:324-32 - PMID: 14717331 - DOI: 10.1162/15353500200303163

Lin Y, Weissleder R, Tung CH

Synthesis and properties of sulfhydryl-reactive near-infrared cyanine fluorochromes for fluorescence imaging Mol Imaging. 2003;2:87-92 - PMID: 12964306 - DOI: 10.1162/15353500200303121

Josephson L, Mahmood U, Wunderbaldinger P, Tang Y, Weissleder R

Pan and sentinel lymph node visualization using a near-infrared fluorescent probe Mol Imaging. 2003;2:18-23 - PMID: 12926234 - DOI: 10.1162/15353500200302154

Funovics MA, Alencar H, Su HS, Khazaie K, Weissleder R, Mahmood U

Miniaturized multichannel near infrared endoscope for mouse imaging Mol Imaging. 2003;2:350-7 - PMID: 14717334 - DOI: 10.1162/15353500200303166

Schellingerhout D, Accorsi R, Mahmood U, Idoine J, Lanza RC, Weissleder R

Coded aperture nuclear scintigraphy: a novel small animal imaging technique Mol Imaging. 2002;1:344-53 - PMID: 12926230 - DOI: 10.1162/15353500200221362

Schellenberger EA, Bogdanov A Jr, Hogemann D, Tait J, Weissleder R, Josephson L

Annexin V-CLIO: a nanoparticle for detecting apoptosis by MRI Mol Imaging. 2002;1:102-7 - PMID: 12920851 - DOI: 10.1162/15353500200202103

Ntziachristos, V, Bremer C, Graves EE, Ripoll J, Weissleder R

In vivo tomographic imaging of near-infrared fluorescent probes Mol Imaging. 2002;1:82-8 - PMID: 12920848 - DOI: 10.1162/15353500200201121

Kircher MF, Josephson L, Weissleder R

Ratio imaging of enzyme activity using dual wavelength optical reporters Mol Imaging. 2003;1:89-95 - PMID: 12920849 - DOI: 10.1162/15353500200201124

Bogdanov A Jr, Matuszewski L, Bremer C, Petrovsky A, Weissleder R

Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets Mol Imaging. 2002;1:16-23 - PMID: 12920857 - DOI: 10.1162/15353500200200001

Chen WT, Tung CH, Weissleder R

Imaging reactive oxygen species in arthritis. Mol Imaging. 2004;3(3):159-62 - PMID: 15530251 - DOI: 10.1162/15353500200404124

Gillies R, Hoffman J, Lam K, Menkens A, Piwnica-Worms D, Sullivan D, Weissleder R.

Meeting Report: High-Throughput Technologies for In Vivo Imaging Agents Mol Imaging. 2005;4:1-6

Wunder A, Schellenberger E, Mahmood U, Bogdanov A Jr, Muller-Ladner U, Weissleder R, Josephson L.

Methotrexate-induced accumulation of fluorescent annexin v in collagen-induced arthritis Mol Imaging. 2005;4(1):1-6 - PMID: 15967121 - DOI: 10.1162/15353500200504142

Montet-Abou K, Montet X, Weissleder R, Josephson L.

Transfection agent induced nanoparticle cell loading Mol Imaging. 2005;4(3):165-71 - PMID: 16194448 - DOI: 10.1162/15353500200505100

Pivovarov M, Bhandary G, Mahmood U, Zahlmann G, Naraghi M, Weissleder R

MIPortal: A High Capacity Server for Molecular Imaging Research. Mol Imaging. 2005;4(4):425-31 - PMID: 16285904 - DOI: 10.2310/7290.2005.05136

Chen WT, Khazaie K, Zhang G, Weissleder R, Tung CH

Detection of dysplastic intestinal adenomas using a fluorescent folate imaging probe Mol Imaging. 2005;4 (1):67-74 - PMID: 15912902

Kelly KA, Clemons PA, Yu AM, Weissleder R

High throughput identification of phage-derived imaging agents Mol Imaging. 2006;5(1):24-30 - PMID: 16779967

Sun EY, Josephson L, Weissleder R.

Clickable nanoparticles for targeted imaging Mol Imaging. 2006;(5) 2:122-128 - PMID: 16954026

Jaffer F, Nahrendorf M, Sosnovik D, Kelly KA, Aikawa E, Weissleder R

Cellular Imaging of Inflammation in Atherosclerosis Using Magnetofluorescent Nanomaterials Mol Imaging. 2006;(5) 2 :85-92 - PMID: 16954022

Zacharakis G, Shih H, Ripoll J, Weissleder R, Ntziachristos V

Normalized transillumination of fluorescent proteins in small animals. Mol Imaging. 2006;5 (2):153-9 - PMID: 16954030

Montet-Abou K, Montet X, Weissleder R, Josephson L

Cell internalization of magnetic nanoparticles using transfection agents. Mol Imaging. 2007;(6) 1:1-9 - PMID: 17311760

Garofalakis A, Zacharakis G, Meyer H, Economou EN, Mamalaki C, Papamatheakis J, Kioussis D, Ntziachristos V, Ripoll J

Three-dimensional in vivo imaging of green fluorescent protein-expressing T cells in mice with noncontact fluorescence molecular tomography. Mol Imaging. 2007;6(2):96-107 - PMID: 17445504

Sheth RA, Upadhyay R, Weissleder R, Mahmood U

Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems. Mol Imaging. 2007;6(3):147-55 - PMID: 17532881

Tam JM, Upadhyay R, Pittet MJ, Weissleder R, Mahmood U

Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging. Mol Imaging. 2007;6(4):269-76 - PMID: 17711782

Hiller K, Waller C, Nahrendorf M, Bauer W, Jakob P

Assessment of cardiovascular apoptosis in the isolated rat heart by magnetic resonance molecular imaging. Mol Imaging. 2006;5(2):115-21 - PMID: 16954025

Runnels J, Zamiri P, Spencer J, Veilleux I, Wei X, Bogdanov AA, Lin CP

Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy. Mol Imaging. 2006;5:31-40 - PMID: 16779968 - PMCID: PMC2801601

Wei X, Sipkins D, Pitsillides C, Novak J, Georgakoudi I, Lin C

Real-time detection of circulating apoptotic cells by in vivo flow cytometry. Mol Imaging. 2005;4:415-6 - PMID: 16285902 - PMCID: PMC2801924 - DOI: 10.2310/7290.2005.05148

Turner GM, Zacharakis G, Soubret A, Ripoll J, Ntziachristos V.

Complete-angle projection diffuse optical tomography by use of early photons Opt Lett. 2005;30(4):409-11 - PMID: 15762444 - DOI: 10.1364/ol.30.000409

Deliolanis N, Lasser T, Hyde D, Soubret A, Ripoll J, Ntziachristos V

Free-space fluorescence molecular tomography utilizing 360 degrees geometry projections. Opt Lett. 2007;32(4):382-4 - PMID: 17356660 - DOI: 10.1364/ol.32.000382

Razansky D, Vinegoni C, Ntziachristos V

Multispectral photoacoustic imaging of fluorochromes in small animals. Opt Lett. 2007;32(19):2891-3 - PMID: 17909608 - DOI: 10.1364/ol.32.002891

Alt C, Veilleux I, Lee H, Pitsillides CM, Cote D, Lin CP

Retinal flow cytometer. Opt Lett. 2007;32:3450-2 - PMID: 18059963 - PMCID: PMC2794483 - DOI: 10.1364/ol.32.003450

Biss DP, Sumorok D, Burns SA, Webb RH, Zhou Y, Bifano TG, Cote D, Veilleux I, Zamiri P, Lin CP

In vivo fluorescent imaging of the mouse retina using adaptive optics. Opt Lett. 2007;32:659-61 - PMID: 17308593 - PMCID: PMC2808135 - DOI: 10.1364/ol.32.000659

Razansky D, Vinegoni C, Ntziachristos V

Polarization-sensitive optoacoustic tomography of optically diffuse tissues. Opt Lett. 2008;33(20):2308-10 - PMID: 18923605 - DOI: 10.1364/ol.33.002308

Jones G, Marks D, Vinegoni C, Boppart S

High-spectral-resolution coherent anti-Stokes Raman scattering with interferometrically detected broadband chirped pulses. Opt Lett. 2006;31(10):1543-5 - PMID: 16642166 - DOI: 10.1364/ol.31.001543

Xu C, Vinegoni C, Ralston T, Luo W, Tan W, Boppart S

Spectroscopic spectral-domain optical coherence microscopy. Opt Lett. 2006;31:1079-81 - PMID: 16625909 - DOI: 10.1364/ol.31.001079

Novak J, Georgakoudi I, Wei X, Prossin A, Lin C

In vivo flow cytometer for real-time detection and quantification of circulating cells. Opt Lett. 2004;29:77-9 - PMID: 14719666 - PMCID: PMC2801600 - DOI: 10.1364/ol.29.000077

Lin C, Webb R

Fiber-coupled multiplexed confocal microscope. Opt Lett. 2000;25:954-6 - PMID: 18064238 - DOI: 10.1364/ol.25.000954

Swanson EA, Izatt JA, Hee MR, Huang D, Lin CP, Schuman JS, Puliafito CA, Fujimoto JG

In vivo retinal imaging by optical coherence tomography. Opt Lett. 1993;18(21):1864-6 - PMID: 19829430 - DOI: 10.1364/ol.18.001864

Ntziachristos V, Weissleder R

Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Opt Lett. 2001;26(12):893-5 - PMID: 18040483 - DOI: 10.1364/ol.26.000893

Ntziachristos V, Ripoll J, Weissleder R

Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Errata. Opt Lett. 2002;27(18):1652 - PMID: 18026531 - DOI: 10.1364/ol.27.001652

Ripoll J, Nieto-Vesperinas M, Weissleder R, Ntziachristos V

Fast analytical approximation for arbitrary geometries in diffuse optical tomography. Opt Lett. 2002;27(7):527-9 - PMID: 18007854 - DOI: 10.1364/ol.27.000527

Ntziachristos V, Ripoll J, Weissleder R

Would near-infrared fluorescence signals propagate through large human organs for clinical studies? Opt Lett. 2002;27(5):333-5 - PMID: 18007794 - DOI: 10.1364/ol.27.000333

Nahrendorf M, Hiller KH, Hu K, Zeijlemaker V, Griswold M, Bauer WR

Pacing in high field cardiac magnetic resonance imaging:. Pacing Clin Electrophysiol. 2004;27(5):671-4 - PMID: 15125728 - DOI: 10.1111/j.1540-8159.2004.00506.x

Veilleux I, Spencer JA, Biss DP, C

In vivo cell tracking with video rate multimodality laser scanning microscopy IEEE J Sel Top Quant. 2008;14:10:18

Lin CP, Kelly MW, Sibayan SA, Latina MA, Anderson RR

Selective Cell Killing by Microparticle Absorption of Pulsed Laser Radiation IEEE J Sel Top Quant. 1999;5:963-8

Allport JR, Shinde Patil VR, Weissleder R

Murine Neuronal Progenitor Cells are Preferentially Recruited to Tumor Vasculature via alpha(4)-integrin and SDF-1alpha-Dependent Mechanisms. Cancer Biol Ther. 2004;3(9):838-44 - PMID: 15254391 - DOI: 10.4161/cbt.3.9.1036

Shah K.

Current Advances in Molecular Imaging of Gene and Cell Therapy for Cancer Cancer Biol Ther. 2005;4(5):518-523 - PMID: 15908803 - DOI: 10.4161/cbt.4.5.1706

Dent P, Yacoub A, Park M, Sarkar D, Shah K, Curiel D, Grant S, Fisher P

Searching for a cure: Gene therapy for glioblastoma. Cancer Biol Ther. 2008;7(9):1335-40 - PMID: 18708757 - DOI: 10.4161/cbt.7.9.6408

Yacoub A, Hamed H, Emdad L, Dos Santos W, Gupta P, Broaddus W, Ramakrishnan V, Sarkar D, Shah K, Curiel D, Grant S, Fisher P, Dent P

MDA-7/IL-24 plus radiation enhance survival in animals with intracranial primary human GBM tumors. Cancer Biol Ther. 2008;7:917-33 - PMID: 18376144 - DOI: 10.4161/cbt.7.6.5928

Wunderbaldinger P, Josephson L, Bremer C, Moore A, Weissleder R

Detection of lymph node metastases by contrast-enhanced MRI in an experimental model Magn Reson Med. 2002;47:292-7 - PMID: 11810672 - DOI: 10.1002/mrm.10068

Moore, A, Sun PZ, Cory D, Hogemann D, Weissleder R, Lipes MA

MRI of insulitis in autoimmune diabetes Magn Reson Med. 2002;47:751-8 - PMID: 11948737 - DOI: 10.1002/mrm.10110

Kim YR, Savellano MD, Savellano DH, Weissleder R, Bogdanov A Jr

Measurement of tumor interstitial volume fraction: Method and implication for drug delivery Magn Reson Med. 2004;52(3):485-94 - PMID: 15334566 - DOI: 10.1002/mrm.20182

Chen JW, Pham W, Weissleder R, Bogdanov A Jr

Human myeloperoxidase: A potential target for molecular MR imaging in atherosclerosis. Magn Reson Med. 2004;52(5):1021-8 - PMID: 15508166 - DOI: 10.1002/mrm.20270

Sosnovik DE, Schellenberger EA, Nahrendorf M, Novikov MS, Matsui T, Dai G, Reynolds F, Grazette L, Rosenzweig A, Weissleder R, Josephson L.

Magnetic resonance imaging of cardiomyocyte apoptosis with a novel magneto-optical nanoparticle Magn Reson Med. 2005;54(3):718-724 - PMID: 16086367 - DOI: 10.1002/mrm.20617

Hong R, Cima MJ, Weissleder R, Josephson L

Magnetic microparticle aggregation for viscosity determination by MR. Magn Reson Med. 2008;59:515-520 - PMID: 18306403 - PMCID: PMC2740908 - DOI: 10.1002/mrm.21526

Schmitt M, Potthast A, Sosnovik DE, Polimeni JR, Wiggins GC, Triantafyllou C, Wald LL

A 128-channel receive-only cardiac coil for highly accelerated cardiac MRI at 3 Tesla. Magn Reson Med. 2008;59:1431-1439 - PMID: 18506789 - PMCID: PMC2548273 - DOI: 10.1002/mrm.21598

Streif J, Nahrendorf M, Hiller K, Waller C, Wiesmann F, Rommel E, Haase A, Bauer W

In vivo assessment of absolute perfusion and intracapillary blood volume in the murine myocardium by spin labeling magnetic resonance imaging. Magn Reson Med. 2005;53(3):584-92 - PMID: 15723416 - DOI: 10.1002/mrm.20327

Zaharchuk G, Bogdanov AA, Marota JJ, Shimizu-Sasamata M, Weisskoff RM, Kwong KK, Jenkins BG, Weissleder R, Rosen BR

Continuous assessment of perfusion by tagging including volume and water extraction (CAPTIVE): a steady-state contrast agent technique for measuring blood flow, relative blood volume fraction, and the water extraction fraction. Magn Reson Med. 1998;40(5):666-78 - PMID: 9797148 - DOI: 10.1002/mrm.1910400504

Mandeville JB, Marota JJ, Kosofsky BE, Keltner JR, Weissleder R, Rosen BR, Weisskoff RM

Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation. Magn Reson Med. 1998;39(4):615-24 - PMID: 9543424 - DOI: 10.1002/mrm.1910390415

Mandeville JB, Moore J, Chesler DA, Garrido L, Weissleder R, Weisskoff RM

Dynamic liver imaging with iron oxide agents: effects of size and biodistribution on contrast. Magn Reson Med. 1997;37(6):885-90 - PMID: 9178240 - DOI: 10.1002/mrm.1910370613

Harika L, Weissleder R, Poss K, Zimmer C, Papisov MI, Brady TJ

MR lymphography with a lymphotropic T1-type MR contrast agent: Gd-DTPA-PGM. Magn Reson Med. 1995;33(1):88-92 - PMID: 7891541 - DOI: 10.1002/mrm.1910330113

Shen T, Weissleder R, Papisov M, Bogdanov A, Brady TJ

Monocrystalline iron oxide nanocompounds (MION): physicochemical properties. Magn Reson Med. 1993;29(5):599-604 - PMID: 8505895 - DOI: 10.1002/mrm.1910290504

Weissleder R

Target-specific superparamagnetic MR contrast agents. Magn Reson Med. 1991;22(2):209-12; discussion 213-5 - PMID: 1812348 - DOI: 10.1002/mrm.1910220209

Streif JU, Herold V, Szimtenings M, Lanz TE, Nahrendorf M, Wiesmann F, Rommel E, Haase A

In vivo time-resolved quantitative motion mapping of the murine myocardium with phase contrast MRI. Magn Reson Med. 2003;49(2):315-21 - PMID: 12541252 - DOI: 10.1002/mrm.10342

Brown D, Breton S

Mitochondria-rich, proton-secreting epithelial cells. J Exp Biol. 1996;199(Pt 11):2345-58 - PMID: 9114500 - DOI: 10.1242/jeb.199.11.2345

Brown D, Smith PJ, Breton S

Role of V-ATPase-rich cells in acidification of the male reproductive tract. J Exp Biol. 1997;200(Pt 2):257-62 - PMID: 9050233 - DOI: 10.1242/jeb.200.2.257

Brown D, Breton S

H(+)V-ATPase-dependent luminal acidification in the kidney collecting duct and the epididymis/vas deferens: vesicle recycling and transcytotic pathways. J Exp Biol. 2000;203(Pt 1):137-45 - PMID: 10600682 - DOI: 10.1242/jeb.203.1.137

Addicks E, Mazitschek R, Giannis A

Synthesis and biological investigation of novel tricyclic benzodiazepinedione-based RGD analogues. Chembiochem. 2002;3(11):1078-88 - PMID: 12404633 - DOI: 10.1002/1439-7633(20021104)3:11<1078::AID-CBIC1078>3.0.CO;2-2

Tung CH, Ho NH, Zeng Q, Tang Y, Jaffer FA, Reed GL, Weissleder R

Novel Factor XIII Probes for Blood Coagulation Imaging Chembiochem. 2003;4:897-899 - PMID: 12964167 - DOI: 10.1002/cbic.200300602

Tung CH, Gerszten RE, Jaffer FA, Weissleder R

A novel near-infrared fluorescence sensor for detection of thrombin activation in blood Chembiochem. 2002;3:207-11 - PMID: 11921399 - DOI: 10.1002/1439-7633(20020301)3:2/3<207::AID-CBIC207>3.0.CO;2-B

Tung CH, Lin Y, Moon WK, Weissleder R

A receptor-targeted near-infrared fluorescence probe for in vivo tumor imaging Chembiochem. 2002;3:784-6 - PMID: 12203978 - DOI: 10.1002/1439-7633(20020802)3:8<784::AID-CBIC784>3.0.CO;2-X

Perez JM, Josephson L, Weissleder R

Use of magnetic nanoparticles as nanosensors to probe for molecular interactions Chembiochem. 2004;5:261-4 - PMID: 14997516 - DOI: 10.1002/cbic.200300730

Schellenberger EA, Reynolds F, Weissleder R, Josephson L

Surface-functionalized nanoparticle library yields probes for apoptotic cells Chembiochem. 2004;5:275-9 - PMID: 14997519 - DOI: 10.1002/cbic.200300713

Schellenberger EA, Weissleder R, Josephson L

Optimal modification of annexin v with fluorescent dyes Chembiochem. 2004;5:271-4 - PMID: 14997518 - DOI: 10.1002/cbic.200300741

Pham W, Kircher MF, Weissleder R, Tung CH

Enhancing membrane permeability by Fatty acylation of oligoarginine peptides. Chembiochem. 2004;5(8):1148-51 - PMID: 15300843 - DOI: 10.1002/cbic.200400063

Koch AM, Reynolds F, Merkle HP, Weissleder R, Josephson L.

Transport Of Surface-Modified Nanoparticles Through Cell Monolayers Chembiochem. 2005;6(2):337-345 - PMID: 15651046 - DOI: 10.1002/cbic.200400174

Law B, Weissleder R, Tung CH.

Mechanism-Based Fluorescent Reporter for Protein Kinase A Detection Chembiochem. 2005;6(8):1361-1367 - PMID: 16010698 - DOI: 10.1002/cbic.200500027

Ho NH, Weissleder R, Tung CH

A Self-Immolative Reporter For beta-Galactosidase Sensing. Chembiochem. 2007;8:560-566 - PMID: 17300128 - DOI: 10.1002/cbic.200600386

Remsen LG, McCormick CI, Roman-Goldstein S, Nilaver G, Weissleder R, Bogdanov A, HellstrÃ¶m I, Kroll RA, Neuwelt EA

MR of carcinoma-specific monoclonal antibody conjugated to monocrystalline iron oxide nanoparticles: the potential for noninvasive diagnosis. AJNR Am J Neuroradiol. 1996;17(3):411-8 - PMID: 8881233 - PMCID: PMC8337991

Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N

Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006;105:445-54 - PMID: 16961141 - DOI: 10.3171/jns.2006.105.3.445

J.W. Chen, R.L. Belford, R.B. Clarkson

Second-Sphere and Outer-Sphere Proton Relaxation of Paramagnetic Contrast Agents J Phys Chem B. 1998;102:2117-2130

J.W. Chen, R.B. Clarkson, R.L. Belford

Rotational Dynamics of MRI Paramagnetic Contrast Agents in Viscous Media J Phys Chem B. 1996;100:8093-8100

J.W. Chen, F.P. Auteri, D.E. Budil, R.L. Belford, R.B. Clarkson

Use of EPR to Investigate Rotational Dynamics of MRI Paramagnetic Contrast Agents J Phys Chem B. 1994;98:13452

Huang XJ, Im HS, Yarimaga O, Kim JH, Lee DH, Kim HS, Choi YK

Direct electrochemistry of uric acid at chemically assembled carboxylated single-walled carbon nanotubes netlike electrode. J Phys Chem B. 2006;110(43):21850-6 - PMID: 17064150 - DOI: 10.1021/jp063749q

Sullivan BM, Harrison-Lavoie KJ, Marshansky V, Lin HY, Kehrl JH, Ausiello DA, Brown D, Druey KM

RGS4 and RGS2 bind coatomer and inhibit COPI association with Golgi membranes and intracellular transport. Mol Biol Cell. 2000;11(9):3155-68 - PMID: 10982407 - PMCID: PMC14982 - DOI: 10.1091/mbc.11.9.3155

Cabrero JR, Serrador JM, Barreiro O, Mittelbrunn M, Naranjo-Suárez S, Martín-Cófreces N, Vicente-Manzanares M, Mazitschek R, Bradner JE, Avila J, Valenzuela-Fernández A, Sánchez-Madrid F

Lymphocyte chemotaxis is regulated by histone deacetylase 6, independently of its deacetylase activity. Mol Biol Cell. 2006;17(8):3435-45 - PMID: 16738306 - PMCID: PMC1525231 - DOI: 10.1091/mbc.E06-01-0008

Tung CH, Mueller S, Weissleder R

Novel branching membrane translocational peptide as gene delivery vector Bioorg Med Chem. 2002;10:3609-14 - PMID: 12213476 - DOI: 10.1016/s0968-0896(02)00248-1

Ho NH, Weissleder R, Tung CH

Development of a dual fluorogenic and chromogenic dipeptidyl peptidase IV substrate. Bioorg Med Chem. 2006;16:2599-2602 - PMID: 16517162 - DOI: 10.1016/j.bmcl.2006.02.045

Jayasena V, Brown D, Shtatland T, Gold L

In vitro selection of RNA specifically cleaved by bacteriophage T4 RegB endonuclease. Biochemistry-US. 1996;35:2349-56 - PMID: 8652576 - DOI: 10.1021/bi951879b

Senior S, Mans L, VanGuilder H, Kelly K, Hendrich M, Elgren T

Catecholase activity associated with copper-S100B. Biochemistry-US. 2003;42:4392-7 - PMID: 12693934 - DOI: 10.1021/bi0205799

Elgren T, Orville A, Kelly K, Lipscomb J, Ohlendorf D, Que L

Crystal structure and resonance Raman studies of protocatechuate 3,4-dioxygenase complexed with 3,4-dihydroxyphenylacetate. Biochemistry-US. 1997;36:11504-13 - PMID: 9298971 - DOI: 10.1021/bi970691k

Guimaraes AR, Rakhlin E, Weissleder R, Thayer SP

Magnetic resonance imaging monitors physiological changes with antihedgehog therapy in pancreatic adenocarcinoma xenograft model. Pancreas. 2008;37(4):440-4 - PMID: 18953259 - PMCID: PMC3806135 - DOI: 10.1097/MPA.0b013e31817c5113

Spear MA, Breakefield XO, Beltzer J, Schuback D, Weissleder R, Pardo FS, Ladner R

Isolation, characterization, and recovery of small peptide phage display epitopes selected against viable malignant glioma cells Cancer Gene Ther. 2001;8:506-11 - PMID: 11498772 - DOI: 10.1038/sj.cgt.7700334

Lin KY, Maricevich M, Bardeesy N, Weissleder R, Mahmood U

In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe. Transl Oncol. 2008;1:84-94 - PMID: 18633456 - PMCID: PMC2510813 - DOI: 10.1593/tlo.08118

Moore A, Marecos E, Simonova M, Weissleder R, Bogdanov A

Novel gliosarcoma cell line expressing green fluorescent protein: A model for quantitative assessment of angiogenesis. Microvasc Res. 1998;56(3):145-53 - PMID: 9828152 - DOI: 10.1006/mvre.1998.2102

Waller C, Hiller KH, Albrecht M, Hu K, Nahrendorf M, Gattenl

Microvascular adaptation to coronary stenosis in the rat heart in vivo: a serial magnetic resonance imaging study. Microvasc Res. 2003;66(3):173-82 - PMID: 14609522 - DOI: 10.1016/s0026-2862(03)00058-x

Graves EE, Ripoll J, Weissleder R, Ntziachristos V

A submillimeter resolution fluorescence molecular imaging system for small animal imaging Med Phys. 2003;30:901-11 - PMID: 12772999 - DOI: 10.1118/1.1568977

Ntziachristos V, Weissleder R

Charge-coupled-device based scanner for tomography of fluorescent near-infrared probes in turbid media Med Phys. 2002;29:803-9 - PMID: 12033576 - DOI: 10.1118/1.1470209

Turner GM, Soubret A, Ntziachristos V

Inversion with early photons. Med Phys. 2007;34(4):1405-11 - PMID: 17500472 - DOI: 10.1118/1.2437103

Razansky D, Ntziachristos V

Hybrid photoacoustic fluorescence molecular tomography using finite-element-based inversion. Med Phys. 2007;34(11):4293-301 - PMID: 18072494 - DOI: 10.1118/1.2786866

Allport JR, Weissleder R

In vivo imaging of gene and cell therapies Exp Hematol. 2001;29:1237-46 - PMID: 11698119 - DOI: 10.1016/s0301-472x(01)00739-1

O'Neill MJ, Weissleder R, Gervais DA, Hahn PF, Mueller PR

Tunneled peritoneal catheter placement under sonographic and fluoroscopic guidance in the palliative treatment of malignant ascites AJR Am J Roentgenol. 2001;177:615-8 - PMID: 11517056 - DOI: 10.2214/ajr.177.3.1770615

Harisinghani MG, Saini S, Weissleder R, Hahn PF, Yantiss RK, Tempany C, Wood BJ, Mueller PR

MR lymphangiography using ultrasmall superparamagnetic iron oxide in patients with primary abdominal and pelvic malignancies: radiographic-pathologic correlation AJR Am J Roentgenol. 1999;172:1347-51 - PMID: 10227514 - DOI: 10.2214/ajr.172.5.10227514

Harisinghani MG, Saksena MA, Hahn PF, King B, Kim J, Torabi MT, Weissleder R

Ferumoxtran-10-Enhanced MR Lymphangiography: Does Contrast-Enhanced Imaging Alone Suffice for Accurate Lymph Node Characterization? AJR Am J Roentgenol. 2006;186(1):144-8 - PMID: 16357394 - DOI: 10.2214/AJR.04.1287

Saksena M, Harisinghani M, Hahn P, Kim J, Saokar A, King B, Weissleder R

Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers. AJR Am J Roentgenol. 2006;187(6):W582-8 - PMID: 17114509 - DOI: 10.2214/AJR.05.0873

Goldberg M, Pivovarov M, Mayo-Smith W, Bhalla M, Blickman J, Bramson R, Boland G, Llewellyn H, Halpern E

Application of wavelet compression to digitized radiographs. AJR Am J Roentgenol. 1994;163:463-8 - PMID: 8037051 - DOI: 10.2214/ajr.163.2.8037051

Pandharipande PV, Harisinghani MG, Ozanne EM, Specht MC, Hur C, Lee JM, Gazelle GS

Staging MR Lymphangiography of the Axilla for Early Breast Cancer: Cost-Effectiveness Analysis. AJR Am J Roentgenol. 2008;191:1308-19 - PMID: 18941062 - DOI: 10.2214/AJR.07.3861

Callahan RJ, Bogdanov A, Fischman AJ, Brady TJ, Weissleder R

Preclinical evaluation and phase I clinical trial of a 99mTc-labeled synthetic polymer used in blood pool imaging. AJR Am J Roentgenol. 1998;171(1):137-43 - PMID: 9648777 - DOI: 10.2214/ajr.171.1.9648777

Weissleder R

Can gadolinium be safely given in renal failure? AJR Am J Roentgenol. 1996;167(1):278-9 - PMID: 8659405 - DOI: 10.2214/ajr.167.1.8659405

Lu DS, Saini S, Hahn PF, Goldberg M, Lee MJ, Weissleder R, Gerard B, Halpern E, Cats A

T2-weighted MR imaging of the upper part of the abdomen: should fat suppression be used routinely? AJR Am J Roentgenol. 1994;162(5):1095-100 - PMID: 8165989 - DOI: 10.2214/ajr.162.5.8165989

Frank H, Weissleder R, Bogdanov AA, Brady TJ

Detection of pulmonary emboli by using MR angiography with MPEG-PL-GdDTPA: an experimental study in rabbits. AJR Am J Roentgenol. 1994;162(5):1041-6 - PMID: 8165978 - DOI: 10.2214/ajr.162.5.8165978

Frank H, Weissleder R, Brady TJ

Enhancement of MR angiography with iron oxide: preliminary studies in whole-blood phantom and in animals. AJR Am J Roentgenol. 1994;162(1):209-13 - PMID: 8273667 - DOI: 10.2214/ajr.162.1.8273667

Chew FS, Weissleder R

Radiation-induced osteochondroma. AJR Am J Roentgenol. 1991;157(4):792 - PMID: 1892038 - DOI: 10.2214/ajr.157.4.1892038

Chew FS, Weissleder R

Mediastinal thymolipoma. AJR Am J Roentgenol. 1991;157(3):468 - PMID: 1872228 - DOI: 10.2214/ajr.157.3.1872228

Weissleder R, Reimer P, Lee AS, Wittenberg J, Brady TJ

MR receptor imaging: ultrasmall iron oxide particles targeted to asialoglycoprotein receptors. AJR Am J Roentgenol. 1990;155(6):1161-7 - PMID: 2122660 - DOI: 10.2214/ajr.155.6.2122660

Fretz CJ, Stark DD, Metz CE, Elizondo G, Weissleder R, Shen JH, Wittenberg J, Simeone J, Ferrucci JT

Detection of hepatic metastases: comparison of contrast-enhanced CT, unenhanced MR imaging, and iron oxide-enhanced MR imaging. AJR Am J Roentgenol. 1990;155(4):763-70 - PMID: 2119106 - DOI: 10.2214/ajr.155.4.2119106

Hahn PF, Stark DD, Saini S, Rummeny E, Elizondo G, Weissleder R, Wittenberg J, Ferrucci JT

The differential diagnosis of ringed hepatic lesions in MR imaging. AJR Am J Roentgenol. 1990;154(2):287-90 - PMID: 2153330 - DOI: 10.2214/ajr.154.2.2153330

Rummeny E, Saini S, Stark DD, Weissleder R, Compton CC, Ferrucci JT

Detection of hepatic metastases with MR imaging: spin-echo vs phase-contrast pulse sequences at 0.6 T. AJR Am J Roentgenol. 1989;153(6):1207-11 - PMID: 2683677 - DOI: 10.2214/ajr.153.6.1207

Rummeny E, Saini S, Wittenberg J, Compton C, Hahn PF, Mueller PR, Simeone JF, Stark DD, Weissleder R, Dousset MG

MR imaging of liver neoplasms. AJR Am J Roentgenol. 1989;152(3):493-9 - PMID: 2536996 - DOI: 10.2214/ajr.152.3.493

Weissleder R, Elizondo G, Stark DD, Hahn PF, Marfil J, Gonzalez JF, Saini S, Todd LE, Ferrucci JT

The diagnosis of splenic lymphoma by MR imaging: value of superparamagnetic iron oxide. AJR Am J Roentgenol. 1989;152(1):175-80 - PMID: 2783273 - DOI: 10.2214/ajr.152.1.175

Weissleder R, Stark DD, Engelstad BL, Bacon BR, Compton CC, White DL, Jacobs P, Lewis J

Superparamagnetic iron oxide: pharmacokinetics and toxicity. AJR Am J Roentgenol. 1989;152(1):167-73 - PMID: 2783272 - DOI: 10.2214/ajr.152.1.167

Rummeny E, Weissleder R, Stark DD, Saini S, Compton CC, Bennett W, Hahn PF, Wittenberg J, Malt RA, Ferrucci JT

Primary liver tumors: diagnosis by MR imaging. AJR Am J Roentgenol. 1989;152(1):63-72 - PMID: 2535770 - DOI: 10.2214/ajr.152.1.63

Wittenberg J, Stark DD, Forman BH, Hahn PF, Saini S, Weissleder R, Rummeny E, Ferrucci JT

Differentiation of hepatic metastases from hepatic hemangiomas and cysts by using MR imaging. AJR Am J Roentgenol. 1988;151(1):79-84 - PMID: 3259825 - DOI: 10.2214/ajr.151.1.79

Hahn PF, Weissleder R, Stark DD, Saini S, Elizondo G, Ferrucci JT

MR imaging of focal splenic tumors. AJR Am J Roentgenol. 1988;150(4):823-7 - PMID: 3279735 - DOI: 10.2214/ajr.150.4.823

Weissleder R, Saini S, Stark DD, Wittenberg J, Ferrucci JT

Dual-contrast MR imaging of liver cancer in rats. AJR Am J Roentgenol. 1988;150(3):561-6 - PMID: 3257610 - DOI: 10.2214/ajr.150.3.561

Weissleder R, Hahn PF, Stark DD, Rummeny E, Saini S, Wittenberg J, Ferrucci JT

MR imaging of splenic metastases: ferrite-enhanced detection in rats. AJR Am J Roentgenol. 1987;149(4):723-6 - PMID: 3498320 - DOI: 10.2214/ajr.149.4.723

Achilefu S, Contag CH, Savitsky AP, Weissleder R

Chemical and Genetic Sensors in Biomedical Research. J Biomed Opt. 2005;10(4):41201 - PMID: 23171967

Graves EE, Yessayan D, Turner G, Weissleder R, Ntziachristos V.

Validation of in vivo fluorochrome concentrations measured using fluorescence molecular tomography J Biomed Opt. 2005;10(4):44019 - PMID: 16178652 - DOI: 10.1117/1.1993427

Ntziachristos V, Turner G, Dunham J, Windsor S, Soubret A, Ripoll J, Shih HA

Planar fluorescence imaging using normalized data. J Biomed Opt. 2005;10(6):64007 - PMID: 16409072 - DOI: 10.1117/1.2136148

Pande AN, Kohler RH, Aikawa E, Weissleder R, Jaffer FA

Detection of macrophage activity in atherosclerosis in vivo using multichannel, high-resolution laser scanning fluorescence microscopy. J Biomed Opt. 2006;11(2):21009 - PMID: 16674184 - DOI: 10.1117/1.2186337

Hsiao JK, Law B, Weissleder R, Tung CH

In-vivo imaging of tumor associated urokinase-type plasminogen activator activity. J Biomed Opt. 2006;11(3):34013 - PMID: 16822063 - DOI: 10.1117/1.2204029

Niedre MJ, Turner GM, Ntziachristos V

Time-resolved imaging of optical coefficients through murine chest cavities. J Biomed Opt. 2006;11(6):064017 - PMID: 17212540 - DOI: 10.1117/1.2400702

Kim P, Puoris'haag M, Cote D, Lin CP, Yun SH

In vivo confocal and multiphoton microendoscopy. J Biomed Opt. 2008;13(1):010501 - PMID: 18315346 - PMCID: PMC2752311 - DOI: 10.1117/1.2839043

Deliolanis NC, Kasmieh R, Wurdinger T, Tannous BA, Shah K, Ntziachristos V

Performance of the red-shifted fluorescent proteins in deep-tissue molecular imaging applications. J Biomed Opt. 2008;13(4):044008 - PMID: 19021336 - PMCID: PMC2749214 - DOI: 10.1117/1.2967184

Lee H, Alt C, Pitsillides C, Lin CP

Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration. J Biomed Opt. 2007;12:064034 - PMID: 18163850 - DOI: 10.1117/1.2804078

Boutrus S, Greiner C, Hwu D, Chan M, Kuperwasser C, Lin CP, Georgakoudi I

Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells. J Biomed Opt. 2007;12:020507 - PMID: 17477705 - PMCID: PMC2798734 - DOI: 10.1117/1.2722733

Roegener J, Brinkmann R, Lin CP

Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells. J Biomed Opt. 2004;9:367-71 - PMID: 15065904 - DOI: 10.1117/1.1646413

Alt C, Framme C, Schnell S, Lee H, Brinkmann R, Lin CP

Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner. J Biomed Opt. 2006;10(6):064014 - PMID: 16409079 - DOI: 10.1117/1.2136314

Tung CH

Fluorescent peptide probes for in vivo diagnostic imaging. Biopolymers. 2004;76(5):391-403 - PMID: 15389488 - DOI: 10.1002/bip.20139

Querol Sans M*, Chen JW*, Weissleder R, Bogdanov AA

Myeloperoxidase Activity Imaging Using (67)Ga Labeled Substrate. Mol Imaging Biol. 2005;7(6):403-10 - PMID: 16292477 - DOI: 10.1007/s11307-005-0020-5

Kelly KA, Nahrendorf M, Yu AM, Reynolds F, Weissleder R

In Vivo Phage Display Selection Yields Atherosclerotic Plaque Targeted Peptides for Imaging. Mol Imaging Biol. 2006;8(4):201-7 - PMID: 16791746 - DOI: 10.1007/s11307-006-0043-6

Mazitschek R, Baumhof P, Giannis A

Peptidomimetics and angiogenesis. Mini Rev Med Chem. 2002;2(5):491-506 - PMID: 12370049 - DOI: 10.2174/1389557023405710

Spear MA, Herrlinger U, Rainov N, Pechan P, Weissleder R, Breakefield XO

Targeting gene therapy vectors to CNS malignancies. J Neurovirol. 1998;4(2):133-47 - PMID: 9584951 - DOI: 10.3109/13550289809114514

Chang K, Jaffer F

Advances in fluorescence imaging of the cardiovascular system. J Nucl Cardiol. 2008;15(3):417-28 - PMID: 18513648 - DOI: 10.1016/j.nuclcard.2008.03.001

Bouley R, Hasler U, Lu HA, Nunes P, Brown D

Bypassing vasopressin receptor signaling pathways in nephrogenic diabetes insipidus. Semin Nephrol. 2008;28:266-78 - PMID: 18519087 - PMCID: PMC2494582 - DOI: 10.1016/j.semnephrol.2008.03.010

Brown D

Aquaporins and vasopressin signaling in kidney health and disease: introduction. Semin Nephrol. 2008;28:215-6 - PMID: 18519082 - DOI: 10.1016/j.semnephrol.2008.03.001

Yeung CH, Breton S, Setiawan I, Xu Y, Lang F, Cooper TG

Increased luminal pH in the epididymis of infertile c-ros knockout mice and the expression of sodium-hydrogen exchangers and vacuolar proton pump H+-ATPase. Mol Reprod Dev. 2004;68(2):159-68 - PMID: 15095336 - DOI: 10.1002/mrd.20067

Ho NH, Weissleder R, Tung CH

Development of water-soluble far-red fluorogenic dyes for enzyme sensing Tetrahedron. 2006;62:578-585

McCarthy JR, Capetta SH, Melfi PJ, Bruckner C

Use of Ag(II) as a removable ion in porphyrin chemistry: Diol cleavage products of [meso-tetraphenyl-2,3-diolchlorinato]Ag(II) Tetrahedron. 2003;59:9137-46

Boiselle PM, Patz EF, Vining DJ, Weissleder R, Shepard JA, McLoud TC

Imaging of mediastinal lymph nodes: CT, MR, and FDG PET. Radiographics. 1998;18(5):1061-9 - PMID: 9747607 - DOI: 10.1148/radiographics.18.5.9747607

Bogdanov A, Wright SC, Marecos EM, Bogdanova A, Martin C, Petherick P, Weissleder R

A long-circulating co-polymer in "passive targeting" to solid tumors. J Drug Target. 1997;4(5):321-30 - PMID: 9169989 - DOI: 10.3109/10611869708995848

Salthouse CD, Weissleder R, Mahmood U

Development of a Time Domain Fluorimeter for Fluorescent Lifetime Multiplexing Analysis. IEEE T Biomed Circuits Syst. 2008;2(3):204-211 - PMID: 19830273 - PMCID: PMC2760943 - DOI: 10.1109/TBCAS.2008.2003195

Soubret A, Ntziachristos V

Fluorescence molecular tomography in the presence of background fluorescence. Phys Med Biol. 2006;51:3983-4001 - PMID: 16885619 - DOI: 10.1088/0031-9155/51/16/007

Papisov M, Weissleder R

Drug delivery to lymphatic tissue. Crit Rev Ther Drug Carrier Syst. 1996;13(1-2):57-84 - PMID: 8853959

Wiesmann F, Herold V, Streiff JU, Nahrendorf M, Neubauer S, Rommel E, Haase A

Novel insights into LV remodeling after murine myocardial infarction by in vivo magnetic resonance tissue velocity mapping. Int J Cardiovasc Imaging. 2004;20(4):289-91 - PMID: 15529911 - DOI: 10.1023/b:caim.0000041945.64887.f4

Breton S, Tyszkowski R, Sabolic I, Brown D

Postnatal development of H+ ATPase (proton-pump)-rich cells in rat epididymis. Histochem Cell Biol. 1999;111(2):97-105 - PMID: 10090570 - DOI: 10.1007/s004180050339

Marshansky V

The V-ATPase a2-subunit as a putative endosomal pH-sensor. Biochem Soc T. 2007;35:1092-9 - PMID: 17956287 - DOI: 10.1042/BST0351092

Kelly KA, Reynolds F, Weissleder R, Josephson L

Fluorescein isothiocyanate-hapten immunoassay for determination of peptide-cell interactions. Anal Biochem. 2004;330(2):181-5 - PMID: 15203322 - DOI: 10.1016/j.ab.2004.02.035

Law B, Hsiao JK, Bugge TH, Weissleder R, Tung CH.

Optical zymography for specific detection of urokinase plasminogen activator activity in biological samples Anal Biochem. 2005;338(1):151-158 - PMID: 15707946 - DOI: 10.1016/j.ab.2004.11.039

Shtatland T, Guettler D, Kossodo M, Pivovarov M, Weissleder R

PepBank - a database of peptides based on sequence text mining and public peptide data sources. BMC Bioinformatics. 2007;8(1):280 - PMID: 17678535 - PMCID: PMC1976427 - DOI: 10.1186/1471-2105-8-280

Rabkin-Aikawa E, Mayer J, Schoen F

Heart valve regeneration. Adv Biochem Eng Biot. 2005;94:141-79 - PMID: 15915872 - DOI: 10.1007/b100003

Schima W, Saini S, Petersein J, Weissleder R, Harisinghani M, Mayo-Smith W, Hahn PF

MR imaging of the liver with Gd-BOPTA: quantitative analysis of T1-weighted images at two different doses J Magn Reson Imaging. 1999;10:80-3 - PMID: 10398981 - DOI: 10.1002/(sici)1522-2586(199907)10:1<80::aid-jmri11>3.0.co;2-s

Hofmann, B, Bogdanov A Jr, Marecos E, Ebert W, Semmler W, Weissleder R

Mechanism of gadophrin-2 accumulation in tumor necrosis J Magn Reson Imaging. 1999;9:336-41 - PMID: 10077034 - DOI: 10.1002/(sici)1522-2586(199902)9:2<336::aid-jmri28>3.0.co;2-3

Enochs WS, Harsh G, Hochberg F, Weissleder R

Improved delineation of human brain tumors on MR images using a long-circulating, superparamagnetic iron oxide agent J Magn Reson Imaging. 1999;9:228-32 - PMID: 10077018 - DOI: 10.1002/(sici)1522-2586(199902)9:2<228::aid-jmri12>3.0.co;2-k

Korosoglou G, Tang L, Kedziorek D, Cosby K, Gilson WD, Vonken EJ, Schar M, Sosnovik D, Kraitchman DL, Weiss RG, Weissleder R, Stuber M

Positive contrast MR-lymphography using inversion recovery with ON-resonant water suppression (IRON). J Magn Reson Imaging. 2008;27(5):1175-1180 - PMID: 18425827 - PMCID: PMC2740932 - DOI: 10.1002/jmri.21337

Nahrendorf M, Wiesmann F, Hiller K, Hu K, Waller C, Ruff J, Lanz T, Neubauer S, Haase A, Ertl G, Bauer W

Serial cine-magnetic resonance imaging of left ventricular remodeling after myocardial infarction in rats. J Magn Reson Imaging. 2001;14(5):547-55 - PMID: 11747006 - DOI: 10.1002/jmri.1218

Reimer P, Bader A, Weissleder R

Preclinical assessment of hepatocyte-targeted MR contrast agents in stable human liver cell cultures. J Magn Reson Imaging. 1998;8(3):687-9 - PMID: 9626887 - DOI: 10.1002/jmri.1880080326

Moore A, Weissleder R, Bogdanov A

Uptake of dextran-coated monocrystalline iron oxides in tumor cells and macrophages. J Magn Reson Imaging. 1998;7(6):1140-5 - PMID: 9400860 - DOI: 10.1002/jmri.1880070629

Weissleder R, Cheng HC, Bogdanova A, Bogdanov A

Magnetically labeled cells can be detected by MR imaging. J Magn Reson Imaging. 1997;7(1):258-63 - PMID: 9039625 - DOI: 10.1002/jmri.1880070140

Stiskal M, Schwickert HC, Demsar F, Roberts TP, Szolar D, Weissleder R, Brasch RC

Contrast enhancement in experimental radiation-induced liver injury: comparison of hepatocellular and reticuloendothelial particulate contrast agents. J Magn Reson Imaging. 1997;6(2):286-90 - PMID: 9132091 - DOI: 10.1002/jmri.1880060205

Reimer P, Saini S, Kwong KK, Cohen MS, Weissleder R, Brady TJ

Dynamic gadolinium-enhanced echo-planar MR imaging of the liver: effect of pulse sequence and dose on enhancement. J Magn Reson Imaging. 1994;4(3):331-5 - PMID: 8061430 - DOI: 10.1002/jmri.1880040318

Enochs WS, Weissleder R

MR imaging of the peripheral nervous system. J Magn Reson Imaging. 1994;4(3):251-7 - PMID: 7520307 - DOI: 10.1002/jmri.1880040306

Weissleder R, Wang YM, Papisov M, Bogdanov A, Schaffer B, Brady TJ, Wittenberg J

Polymeric contrast agents for MR imaging of adrenal glands. J Magn Reson Imaging. 1993;3(1):93-7 - PMID: 8428107 - DOI: 10.1002/jmri.1880030116

Reimer P, Kwong KK, Weisskoff R, Cohen MS, Brady TJ, Weissleder R

Dynamic signal intensity changes in liver with superparamagnetic MR contrast agents. J Magn Reson Imaging. 1992;2(2):177-81 - PMID: 1562768 - DOI: 10.1002/jmri.1880020210

Weissleder R, Papisov M

Pharmaceutical iron oxides for MR imaging J Magn Reson Imaging. 1992;4:1-6

Sosnovik DE, Dai G, Nahrendorf M, Rosen BR, Seethamraju R

Cardiac MRI in mice at 9.4 Tesla with a transmit-receive surface coil and a cardiac-tailored intensity-correction algorithm. J Magn Reson Imaging. 2007;26(2):279-87 - PMID: 17654729 - DOI: 10.1002/jmri.20966

Streif JU, Hiller KH, Waller C, Nahrendorf M, Wiesmann F, Bauer WR, Rommel E, Haase A

In vivo assessment of absolute perfusion in the murine skeletal muscle with spin labeling MRI. Magnetic resonance imaging. J Magn Reson Imaging. 2003;17(1):147-52 - PMID: 12500285 - DOI: 10.1002/jmri.10229

Osborn EA, Jaffer FA

Advances in molecular imaging of atherosclerotic vascular disease. Curr Opin Cardiol. 2008;23:620-8 - PMID: 18830079 - PMCID: PMC3984946 - DOI: 10.1097/HCO.0b013e328310fc7e

Vinegoni C, Karlsson M, Petersson M, Sunnerud H

Statistics of polarization-dependent loss in a recirculating loop. J Lightwave Technol. 2004;22:968-76

Wegmuller M, Oberson P, Guinnard O, Huttner B, Guinnard L, Vinegoni C, Gisin N

Distributed gain measurements in Er-doped fibers with high resolution and accuracy using an Optical Frequency Domain Reflectometer. J Lightwave Technol. 2000;18:2127-32

Low A, O'Donnell C, Kathiresan S, Everett B, Chae C, Shaw S, Ellinor P, MacRae C

Aging syndrome genes and premature coronary artery disease. BMC Med Genet. 2005;6:38 - PMID: 16262891 - PMCID: PMC1289285 - DOI: 10.1186/1471-2350-6-38

Neuwelt EA, Weissleder R, Nilaver G, Kroll RA, Roman-Goldstein S, Szumowski J, Pagel MA, Jones RS, Remsen LG, McCormick CI

Delivery of virus-sized iron oxide particles to rodent CNS neurons. Neurosurgery. 1994;34(4):777-84 - PMID: 8008188 - DOI: 10.1227/00006123-199404000-00048

Da Silva N, Shum WW, Breton S

Regulation of vacuolar proton pumping ATPase-dependent luminal acidification in the epididymis. Asian J Androl. 2007;9(4):476-82 - PMID: 17589784 - DOI: 10.1111/j.1745-7262.2007.00299.x

Zhu B, Jaffer F, Nztiachristos V, Weissleder R

Development of a near infrared fluorescence catheter: operating characteristics and feasibility for atherosclerotic plaque detection J Phys D Appl Phys. 2005;38:2701-2707

Bogdanov A, Petherick P, Marecos E, Weissleder R

In vivo localization of diglycylcysteine-bearing synthetic peptides by nuclear imaging of oxotechnetate transchelation. Nucl Med Biol. 1997;24(8):739-42 - PMID: 9428599 - DOI: 10.1016/s0969-8051(97)00117-0

Weissleder R, Reimer P

Iron oxide based magnetopharmaceuticals for MR imaging Eur J Radiol. 1993;3:198-212

Ntziachristos V, Bremer C, Weissleder R

Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging Eur J Radiol. 2002;13:195-208 - PMID: 12541130 - DOI: 10.1007/s00330-002-1524-x

Bremer C, Ntziachristos V, Weissleder R

Optical-based molecular imaging: contrast agents and potential medical applications Eur J Radiol. 2002;13:231-43 - PMID: 12598985 - DOI: 10.1007/s00330-002-1610-0

Wunderbaldinger P, Bogdanov A, Weissleder R

New approaches for imaging in gene therapy Eur J Radiol. 2000;34:156-65 - PMID: 10927158 - DOI: 10.1016/s0720-048x(00)00196-0

Saksena MA, Saokar A, Harisinghani MG

Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging. Eur J Radiol. 2006;58(3):367-74 - PMID: 16472955 - DOI: 10.1016/j.ejrad.2005.12.041

Boland GW, Guimaraes AS, Mueller PR

Radiology report turnaround: expectations and solutions. Eur J Radiol. 2008;18(7):1326-8 - PMID: 18327594 - DOI: 10.1007/s00330-008-0905-1

Boland GW, Guimaraes AS, Mueller PR

The radiologist's conundrum: benefits and costs of increasing CT capacity and utilization. Eur J Radiol. 2008;19(1):9-11; discussion 12 - PMID: 18766347 - DOI: 10.1007/s00330-008-1159-7

Berteloot A, Malo C, Breton S, Brunette M

Fast sampling, rapid filtration apparatus: principal characteristics and validation from studies of D-glucose transport in human jejunal brush-border membrane vesicles. J Membr Biol. 1991;122(2):111-25 - PMID: 1895337 - DOI: 10.1007/BF01872635

Laprade R, Lapointe JY, Breton S, Duplain M, Cardinal J

Intracellular potassium activity in mammalian proximal tubule: effect of perturbations in transepithelial sodium transport. J Membr Biol. 1991;121(3):249-59 - PMID: 1865489 - DOI: 10.1007/BF01951558

Macri P, Breton S, Marsolais M, Lapointe J, Laprade R

Hypertonicity decreases basolateral K+ and Cl- conductances in rabbit proximal convoluted tubule. J Membr Biol. 1997;155(3):229-37 - PMID: 9050446 - DOI: 10.1007/s002329900175

Brinkmann R, Koop N, Ozdemir M, Alt C, Sch

Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam. Laser Surg Med. 2003;32:252-64 - PMID: 12696092 - DOI: 10.1002/lsm.10150

Lin C, Weaver Y, Birngruber R, Fujimoto J, Puliafito CP

Intraocular microsurgery with a picosecond Nd:YAG laser. Laser Surg Med. 1995;15:44-53 - PMID: 7997047 - DOI: 10.1002/lsm.1900150107

Brinkmann R, H

Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen. Laser Surg Med. 2000;27(5):451-64 - PMID: 11126439 - DOI: 10.1002/1096-9101(2000)27:5<451::AID-LSM1006>3.0.CO;2-1

Harisinghani MG, Saksena M, Ross RW, Tabatabaei S, Dahl D, McDougal S, Weissleder R

A pilot study of lymphotrophic nanoparticle-enhanced magnetic resonance imaging technique in early stage testicular cancer: a new method for noninvasive lymph node evaluation. Urology. 2005;66(5):1066-71 - PMID: 16286125 - DOI: 10.1016/j.urology.2005.05.049

Guimaraes AR, Tabatabei S, Dahl D, McDougal WS, Weissleder R, Harisinghani MG

Pilot Study Evaluating Use of Lymphotrophic Nanoparticle-Enhanced Magnetic Resonance Imaging for Assessing Lymph Nodes in Renal Cell Cancer. Urology. 2008;71(4):708-12 - PMID: 18295316 - DOI: 10.1016/j.urology.2007.11.096

Pittet M, Speiser D, Valmori D, Rimoldi D, Lienard D, Lejeune F, Cerottini J, Romero P

Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients. Int Immunopharmacol. 2001;1:1235-47 - PMID: 11460305 - DOI: 10.1016/s1567-5769(01)00048-0

Simonova M, Weissleder R, Sergeyev N, Vilissova N, Bogdanov A Jr

Targeting of green fluorescent protein expression to the cell surface Biochem Bioph Res Co. 1999;262:638-42 - PMID: 10471377 - DOI: 10.1006/bbrc.1999.1251

Choi HK, Yessayan D, Choi HJ, Schellenberger E, Bogdanov A, Josephson L, Weissleder R, Ntziachristos V.

Quantitative analysis of chemotherapeutic effects in tumors using in vivo staining and correlative histology Cell Oncol. 2005;27(3):183-90 - PMID: 16037639 - PMCID: PMC4615174 - DOI: 10.1155/2005/791936

Schoepf U, Marecos EM, Melder RJ, Jain RK, Weissleder R

Intracellular magnetic labeling of lymphocytes for in vivo trafficking studies. Biotechniques. 1998;24(4):642-6, 648-51 - PMID: 9564539 - DOI: 10.2144/98244rr01

Pham W, Weissleder R, Tung CH

A practical approach for the preparation of monofunctional azulenyl squaraine dye. Tetrahedron Lett. 2003;44(20):3975-3978 - PMID: 20740053 - PMCID: PMC2926986 - DOI: 10.1016/S0040-4039(03)00819-0

Pham W, Weissleder R, Tung CH

Intermolecular [8+2] cycloaddition reactions of 2H-3-methoxycarbonylcyclohepta[b]furan-2-one with vinyl ethers: an approach to bicyclo[5.3.0]azulene derivatives. Tetrahedron Lett. 2002;43(1):19-20 - PMID: 20740048 - PMCID: PMC2926969 - DOI: 10.1016/S0040-4039(01)02061-5

Hilderbrand SA, Weissleder R

One-Pot Synthesis of New Symmetric and Asymmetric Xanthene Dyes. Tetrahedron Lett. 2007;48(25):4383-4385 - PMID: 19834587 - PMCID: PMC2761723 - DOI: 10.1016/j.tetlet.2007.04.088

Panchenko MP, Silva N, Stone JR

Up-regulation of a hydrogen peroxide-responsive pre-mRNA binding protein in atherosclerosis and intimal hyperplasia. Cardiovasc Pathol. 2008;18(3):167-72 - PMID: 18508286 - PMCID: PMC2723736 - DOI: 10.1016/j.carpath.2008.03.008

Rabkin E, Schoen F

Cardiovascular tissue engineering. Cardiovasc Pathol. 2002;11:305-17 - PMID: 12459430 - DOI: 10.1016/s1054-8807(02)00130-8

Mendelson K, Aikawa E, Mettler B, Sales V, Martin D, Mayer J, Schoen F

Healing and remodeling of bioengineered pulmonary artery patches implanted in sheep. Cardiovasc Pathol. 2007;16:277-82 - PMID: 17868878 - DOI: 10.1016/j.carpath.2007.03.008

Collins AB, Smith RN, Stone JR

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Quantitative point source photoacoustic inversion formulas for scattering and absorbing media Hys Rev E Stat Nonlin Soft Matter Phys. 2005;71(3 Pt 1):031912 - PMID: 15903464 - DOI: 10.1103/PhysRevE.71.031912

Dodd CH, Hsu HC, Chu WJ, Yang P, Zhang HG, Mountz JD Jr, Zinn K, Forder J, Josephson L, Weissleder R, Mountz JM, Mountz JD

Normal T-cell response and in vivo magnetic resonance imaging of T cells loaded with HIV transactivator-peptide-derived superparamagnetic nanoparticles J Immunol Methods. 2001;256:89-105 - PMID: 11516758 - DOI: 10.1016/s0022-1759(01)00433-1

Kuzmin A, Purans J, Cazzanelli E, Vinegoni C, Mariotto G

XRD, EXAFS and Raman spectroscopy studies of pure ground WO3 and mixed W1-xRexO3-y polycrystals J Appl Phys. 1998;84:5515-24

Simonova M, Shtanko O, Sergeyev N, Weissleder R, Bogdanov A Jr

Engineering of technetium-99m-binding artificial receptors for imaging gene expression J Gene Med. 2003;5:1056-66 - PMID: 14661181 - DOI: 10.1002/jgm.448

Giorgis F, Pirri CF, Vinegoni C, Pavesi L

Radiative emission properties of a-SiN:H based alloys, nanometric multilayers and light emitting devices J Lumin. 1998;80:423-427

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New clinical imaging modalities in prostate cancer. Hematol Oncol Clin N. 2006;20(4):811-30 - PMID: 16861116 - DOI: 10.1016/j.hoc.2006.03.009

Petersein J, Saini S, Weissleder R

Liver. II: Iron oxide-based reticuloendothelial contrast agents for MR imaging. Clinical review. Magn Reson Imaging. 1996;4(1):53-60 - PMID: 8673716

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Targeted contrast agents in MR imaging. Magn Reson Imaging. 1996;4(1):171-84 - PMID: 8673713

Bader A, Reimer P, Knop E, Boker K, Christians U, Weissleder R, Sewing KF

An organotypical in vitro model of the liver parenchyma for uptake studies of diagnostic MR receptor agents. Magn Reson Imaging. 1996;13(7):991-1002 - PMID: 8583878 - DOI: 10.1016/0730-725x(95)00053-j

Schaffer BK, Linker C, Papisov M, Tsai E, Nossiff N, Shibata T, Bogdanov A, Brady TJ, Weissleder R

MION-ASF: biokinetics of an MR receptor agent. Magn Reson Imaging. 1993;11(3):411-7 - PMID: 7685055 - DOI: 10.1016/0730-725x(93)90074-n

Chen MC, Tsang YM, Stark DD, Weissleder R, Saini S, Brandhorst J, White DL, Engelstad BL, Ferrucci JT

Hepatic metastases: rat models for imaging research. Magn Reson Imaging. 1989;7(1):1-8 - PMID: 2918813 - DOI: 10.1016/0730-725x(89)90318-4

Weissleder R, Stark DD, Elizondo G, Hahn PF, Compton C, Saini S, Wittenberg J, Ferrucci JT

MRI of hepatic lymphoma. Magn Reson Imaging. 1989;6(6):675-81 - PMID: 3062298 - DOI: 10.1016/0730-725x(88)90092-6

Weissleder R, Stark DD, Compton CC, Simeone JF, Ferrucci JT

Cholecystitis: diagnosis by MR imaging. Magn Reson Imaging. 1988;6(3):345-8 - PMID: 3398743 - DOI: 10.1016/0730-725x(88)90412-2

Cazzanelli E, Vinegoni C, Mariotto G, Kuzmin A, Purans J

Raman and XRD spectroscopic investigations of polymorphism in tungsten trioxide powders Solid State Ionics. 1999;123:67-74

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Comparative Raman study of the monoclinic-to-tetragonal phase transition in tungsten trioxide WO3 at high temperature and upon hydrogen insertion J Solid State Chem. 1999;143:24-32

Petersson M, Vinegoni C, Sunnerud H, Karlsson M

Statistics of PMD in recirculating loops. IEEE Photonic Tech L. 2003;15:1543-5

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Distributed measurements of chromatic dispersion and nonlinear coefficient in low PMD dispersion shifted fibers IEEE Photonic Tech L. 2003;15:739-40

Wegmuller M, Demma S, Vinegoni C, Gisin N

Emulator of first- and second-order polarization mode dispersion. IEEE Photonic Tech L. 2002;14:630-2

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Measurements of the nonlinear coefficient of standard SMF,DSF, and DSC fibers using a self-aligned interferometer and a Faraday mirror IEEE Photonic Tech L. 2001;13:1337-9

Wegmuller M, Legre M, Oberson P, Guinnard O, Guinnard L, Vinegoni C, Gisin N

Analysis of the polarization evolution in a ribbon cable using high resolution OFDR IEEE Photonic Tech L. 2000;13:145-7

Xia Z, Huang X, Zhou X, Sun Y, Ntziachristos V, Wong S.

Registration of 3-D CT and 2-D Flat Images of Mouse via Affine Transformation IEEE T Inf Technol B. 0;12:569-578

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A spectroscopic and computational study of the singlet and triplet excited states of synthetic beta-functionalized chlorins Chem Phys. 2003;294:285-303

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Prostate cancer imaging-what the urologic oncologist needs to know. Radiol Clin North Am. 2006;44(5):711-22 - PMID: 17030222 - DOI: 10.1016/j.rcl.2006.07.002

Kim YR, Savellano MD, Weissleder R, Bogdanov A Jr

Steady-state and dynamic contrast MR imaging of human prostate cancer xenograft tumors: a comparative study Technol Cancer Res T. 2002;1:489-95 - PMID: 12625776 - DOI: 10.1177/153303460200100609

Vinegoni C, Cazzanelli M, Trivelli A, Lunney GJ, Mariotto G, Levy J

Morphological and optical characterization of GaN prepared by pulsed laser ablation Surf Coat Tech. 2000;124:272-7

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Engineering membrane proteins for nuclear medicine: applications for gene therapy and cell tracking Q J Nucl Med Mol IM. 2000;44:224-35 - PMID: 11105587

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Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging. Abdom Imaging. 2006;31(6):660-7 - PMID: 16680506 - DOI: 10.1007/s00261-006-9006-2

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Luminescence properties of GaN thin films prepared by pulsed laser deposition Mat Sci Eng B-Solid. 1999;59:137-140

Harisinghani MG, Jhaveri KS, Weissleder R, Schima W, Saini S, Hahn PF, Mueller PR

MRI contrast agents for evaluating focal hepatic lesions Clin Radiol. 2001;56:714-25 - PMID: 11585393 - DOI: 10.1053/crad.2001.0764

Johnson J, Swirski F, Gajewska B, Wiley R, Fattouh R, Pacitto S, Wong J, Stampfli M, Jordana M

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Measurement of nonlinear polarization rotation in high birefringence optical fibers at telecom wavelength. 2000;2;314-184 J Opt A-Pure Appl Opt . 2000;2:314-184

Grimm J, Wunder A.

Current state of molecular imaging research Rofo-Fortschr Rontg. 2005;177(3):326-37 - PMID: 15719293 - DOI: 10.1055/s-2005-857946

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Imaging cellular responses to mechanical stimuli within three-dimensional tissue constructs. Microsc Res Techniq. 2007;70(4):361-71 - PMID: 17262787 - DOI: 10.1002/jemt.20420

Harisinghani MG, Saini S, Weissleder R, Rubin D, deLange E, Harms S, Weinreb J, Small W, Sukerkar A, Brown JJ, Zelch J, Lucas M, Morris M, Hahn PF

Splenic imaging with ultrasmall superparamagnetic iron oxide ferumoxtran-10 (AMI-7227): preliminary observations J Comput Assist Tomogr. 2001;25:770-6 - PMID: 11584239 - DOI: 10.1097/00004728-200109000-00017

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All optical switching in a highly birefringent and a standard telecom fiber using a Faraday mirror stabilization scheme. Opt Commun. 2000;182:314-18

Lee H, Purdon AM, Westervelt RM

Micromanipulation of biological systems with microelectromagnets IEEE T Magn. 0;40(4):2991 - 2993

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Sonographic diagnosis of subclavian and internal jugular vein thrombosis. J Ultrasound Med. 1987;6(10):577-87 - PMID: 3316690 - DOI: 10.7863/jum.1987.6.10.577

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Classification of fluorescence in-situ hybridization images using belief networks Pattern Recogn Lett. 2004;25(16):1777-85

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MR imaging of neuronal transport in the guinea pig facial nerve: initial findings. Acta Otolaryngol. 1995;115(4):512-6 - PMID: 7572127 - DOI: 10.3109/00016489509139358

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Determination of the nonlinear coefficient n2/Aeff using a self-aligned interferometer and a Faraday mirror. . 2000;36;886 Electronic Lett. 2000;36:886-87

Sakamoto I, Takahashi T, Ueno T, Kakita A, Hayashi I, Yamashina S

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Mouse Models of Human Non-Small-Cell Lung Cancer: Raising the Bar. Cold Spring Harb Symp Quant Biol. 2005;70:241-250 - PMID: 16869760 - DOI: 10.1101/sqb.2005.70.037

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DNA knot formation in aqueous solutions J Knot Theor Ramif. 1994;3:287-294

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[Experimental and clinical approaches to lymph node imaging] Radiologe. 2001;41:121-30 - PMID: 11253097 - DOI: 10.1007/s001170050954

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Advances in cardiovascular medicine through molecular imaging. Radiologe. 2007;47(1):18-24 - PMID: 17187263 - DOI: 10.1007/s00117-006-1450-z

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Cell tracking : Principles and applications. Radiologe. 2007;47(1):25-33 - PMID: 17187264 - DOI: 10.1007/s00117-006-1449-5

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Molecular imaging -a new emphasis in radiology Radiologe. 2007;47(1):6-7 - PMID: 17136404 - DOI: 10.1007/s00117-006-1447-7

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Drug targeting in magnetic resonance imaging. Magn Reson Q. 1992;8(1):55-63 - PMID: 1567758

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Contrast agents for magnetic resonance imaging of the liver. Targeted Diagn Ther. 1992;4:163-87 - PMID: 1797156

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Magnetic resonance imaging of the liver. Magn Reson Q. 1989;5(2):97-121 - PMID: 2701280

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Physical principles of magnetic resonance imaging Rev Mex Radiol. 1989;43:3-12

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Appllications of In Vivo Molecular Imaging in Biology and Medicine Neoreviews. 2000;1:233-240

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Strategies in in vivo molecular imaging Neoreviews. 2000;1:225-232

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23Na microscopy of the mouse heart in vivo using density-weighted chemical shift imaging. MAGMA. 2004;17(3-6):196-200 - PMID: 15580377 - DOI: 10.1007/s10334-004-0048-6

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Tekirian TL, Merriam DE, Marshansky V, Miller J, Crowley AC, Chan H, Ausiello D, Brown D, Buxbaum JD, Xia W, Wasco W

Subcellular localization of presenilin 2 endoproteolytic C-terminal fragments. Brain Res Mol Brain Res. 2001;96(1-2):14-20 - PMID: 11731004 - DOI: 10.1016/s0169-328x(01)00250-9

Kirkin V, Mazitschek R, Krishnan J, Steffen A, Waltenberger J, Pepper MS, Giannis A, Sleeman JP

Characterization of indolinones which preferentially inhibit VEGF-C- and VEGF-D-induced activation of VEGFR-3 rather than VEGFR-2. Eur J Biochem. 2001;268(21):5530-40 - PMID: 11683876 - DOI: 10.1046/j.1432-1033.2001.02476.x

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Learning Bayesian Networks for Cytogenetic Image Classification ICPR. 2006;2:772-5

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Functional G-CSF pathways in t(8;21) leukemic cells allow for differentiation induction and degradation of AML1-ETO. Hematol J. 2002;1(5):316-28 - PMID: 11920209 - DOI: 10.1038/sj.thj.6200047

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During U937 monocytic differentiation repression of the CD43 gene promoter is mediated by the single-stranded DNA binding protein Pur alpha. Br J Haematol. 2001;115(1):159-66 - PMID: 11722429 - DOI: 10.1046/j.1365-2141.2001.03066.x

Shelley CS, Da Silva N, Georgakis A, Chomienne C, Arnaout MA

Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb. Genomics. 1998;49(2):334-6 - PMID: 9598326 - DOI: 10.1006/geno.1998.5232

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Kim TW, Hung CF, Zheng M, Boyd DA, He L, Pai SI, Wu TC

A DNA vaccine co-expressing antigen and an anti-apoptotic molecule further enhances the antigen-specific CD8+ T-cell immune response. J Biomed Sci. 2004;11(4):493-9 - PMID: 15153784 - DOI: 10.1007/BF02256098

Dong SM, Pai SI, Rha SH, Hildesheim A, Kurman RJ, Schwartz PE, Mortel R, McGowan L, Greenberg MD, Barnes WA, Sidransky D

Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma. Cancer Epidemiol Biomarkers Prev. 2002;11(1):3-6 - PMID: 11815394

Cheng WF, Hung CF, Pai SI, Hsu KF, He L, Ling M, Wu TC

Repeated DNA vaccinations elicited qualitatively different cytotoxic T lymphocytes and improved protective antitumor effects. J Biomed Sci. 2002;9(6 Pt 2):675-87 - PMID: 12432234 - DOI: 10.1159/000067285

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