Miller, Miles , PhD
Miles Miller received his A.B. in Chemistry from Princeton University, and his Ph.D. in Biological Engineering from the Massachusetts Institute of Technology (Advisors: Douglas Lauffenburger and Linda Griffith). He trained as a NIH postdoctoral fellow under Dr. Ralph Weissleder at MGH. He specializes in parsing mechanisms of cell signaling and drug action from a quantitative network-level perspective, with training in computational modeling, imaging, nanotechnology, cell signaling biology, and drug delivery.
Selected Publications (from total of 41)
Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease
It’s what’s inside that counts for nanoparticle vaccines
Modification of proteolytic activity matrix analysis (PrAMA) to measure ADAM10 and ADAM17 sheddase activities in cell and tissue lysates.
Less is more for anticancer therapy combinations
Nanotransfection brings progress that’s more than skin-deep
Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior
Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis.
Counting on carbon quantum dots to clear infection
Prediction of Anti-cancer Nanotherapy Efficacy by Imaging
Nano-palladium is a cellular catalyst for in vivo chemistry
Imaging of anticancer drug action in single cells
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts
Driver mutations take the wheel in invasive yet nonmalignant disease.
In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy
Nanoparticles improve economic mileage for CARs.