PI Bio

Lin, Herbert, MD, PhD

Phone: 617-726-5661

Selected Publications (from total of 66)

Liu J, Wang W, Liu M, Su L, Zhou H, Xia Y, Ran J, Lin HY, Yang B
Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway.
Cell Signal. 2016;28(12):1842-1851 - PMID: 27575743
Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt LM, Holderried TA, Seifert M, Sopper S, Fenn AM, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber GF, Harder NK, Chousterman BG, Arvedson TL, McKee M, Wang F, Lutz OM, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin HY, Swirski FK
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver
Nature Med. 2016;22(8):945-951 - PMID: 27428900 - PMCID: PMC4957133
Meng C, Liu W, Huang H, Wang Y, Chen B, Freeman GJ, Schneyer A, Lin HY, Xia Y
Repulsive Guidance Molecule b (RGMb) Is Dispensable for Normal Gonadal Function in Mice.
Biol Reprod. 2016;94(4):78 - PMID: 26911425
Nai A, Rubio A, Campanella A, Gourbeyre O, Artuso I, Bordini J, Gineste A, Latour C, Besson-Fournier C, Lin HY, Coppin H, Roth MP, Camaschella C, Silvestri L, Meynard D
Limiting hepatic Bmp-Smad signaling by matriptase-2 is required for erythropoietin-mediated hepcidin suppression in mice.
Blood. 2016;127(19):2327-36 - PMID: 26755707 - PMCID: PMC4865590
David V, Martin A, Isakova T, Spaulding C, Qi L, Ramirez V, Zumbrennen-Bullough KB, Sun CC, Lin HY, Babitt JL, Wolf M
Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production.
Kidney Int. 2015;89(1):135-46 - PMID: 26535997 - PMCID: PMC4854810
Schaefer B, Haschka D, Finkenstedt A, Petersen BS, Theurl I, Henninger B, Janecke AR, Wang CY, Lin HY, Veits L, Vogel W, Weiss G, Franke A, Zoller H
Impaired Hepcidin Expression in Alpha-1-Antitrypsin Deficiency Associated with Iron Overload and Progressive Liver Disease.
Hum Mol Genet. 2015;24(21):6254-63 - PMID: 26310624 - PMCID: PMC4599680
Samir AE, Allegretti AS, Zhu Q, Dhyani M, Anvari A, Sullivan DA, Trottier CA, Dougherty S, Williams WW, Babitt JL, Wenger J, Thadhani RI, Lin HY
Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys.
BMC Nephrol. 2015;16(1):119 - PMID: 26227484 - PMCID: PMC4521488
Tesfay L, Clausen KA, Kim JW, Hedge P, Wang X, Miller LD, Deng Z, Blanchette N, Arvedson T, Miranti CK, Babitt JL, Lin HY, Peehl DM, Torti FM, Torti SV
Hepcidin regulation in prostate and its disruption in prostate cancer.
Cancer Res. 2015;75(11):2254-63 - PMID: 25858146 - PMCID: PMC4454355
Pauk M, Grgurevic L, Brkljacic J, Kufner V, Bordukalo-Niksic T, Grabusic K, Razdorov G, Rogic D, Zuvic M, Oppermann H, Babitt JL, Lin HY, Volarevic S, Vukicevic S
Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice.
Int Orthop. 2014;39(1):161-172 - PMID: 25300398
Wang CY, Meynard D, Lin HY
The role of TMPRSS6/matriptase-2 in iron regulation and anemia.
Front Pharmacol. 2014;5:114 - PMID: 24966834 - PMCID: PMC4053654
Babitt JL, Lin HY
BuMPing iron with modified heparins.
Blood. 2014;123(10):1440-1 - PMID: 24627550 - PMCID: PMC3945857
Hilgendorf I, Theurl I, Gerhardt LM, Robbins CS, Weber GF, Gonen A, Iwamoto Y, Degousee N, Holderried TA, Winter C, Zirlik A, Lin HY, Sukhova GK, Butany J, Rubin BB, Witztum JL, Libby P, Nahrendorf M, Weissleder R, Swirski FK
Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating TH1 Adaptive Immunity.
Circulation. 2014;129(16):1677-87 - PMID: 24488984 - PMCID: PMC3997655
Meynard D, Sun CC, Wu Q, Chen W, Chen S, Nelson CN, Waters MJ, Babitt JL, Lin HY
Inflammation Regulates TMPRSS6 Expression via STAT5.
PLoS ONE. 2013;8(12):e82127 - PMID: 24376517 - PMCID: PMC3871639
Meynard D, Babitt JL, Lin HY
The liver: conductor of systemic iron regulation.
Blood. 2013;123(2):168-76 - PMID: 24200681 - PMCID: PMC3888285
Krause DS, Fulzele K, Catic A, Sun CC, Dombkowski D, Hurley MP, Lezeau S, Attar E, Wu JY, Lin HY, Divieti-Pajevic P, Hasserjian RP, Schipani E, Van Etten RA, Scadden DT
Differential regulation of myeloid leukemias by the bone marrow microenvironment.
Nature Med. 2013;19(11):1513-7 - PMID: 24162813 - PMCID: PMC3827980