Brown, Dennis, PhD
Dennis Brown is a Ph. D. cell biologist who specializes in the use of state-of-the art fluorescence imaging and electron microscopy techniques to follow and dissect physiologically-relevant membrane protein trafficking events in epithelial and non-epithelial cells. He serves as the Associate Director of the CSB and the Director of the MGH Program in Membrane Biology (PMB) which uses use state of the art technologies in the pursuit of important biological questions at the system level. He became Professor of Medicine at Harvard in 2001 and has been at MGH since 1985.
Hypertonic stress promotes autophagy and microtubule-dependent autophagosomal clusters.
Aquaporin-2 Inhibitors: Fishing in the Chemical Pool.
Defining Kidney Biology to Understand Renal Disease.
Regulation of Luminal Acidification by the V-ATPase.
Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.
High resolution helium ion scanning microscopy of the rat kidney.
Circulating aldosterone induces the apical accumulation of the proton pumping V-ATPase and increases proton secretion in clear cells in the caput epididymis.
Vasopressin induces apical expression of caveolin in rat kidney collecting duct principal cells.
Plasticity of basal cells during postnatal development in the rat epididymis.