mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation.
Blood. 2013;122(14):e23-e32 - PMID: 23980067 - PMCID: PMC3790516 - DOI: 10.1182/blood-2013-04-495119
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling.
A new image of the hematopoietic stem cell vascular niche.
Cell Stem Cell. 2013;13(5):514-6 - PMID: 24209758 - PMCID: PMC4148778 - DOI: 10.1016/j.stem.2013.10.012
Stress-induced hematopoietic failure in the absence of immediate early response gene X-1.
Haematologica. 2013;99(2):282-91 - PMID: 24056813 - PMCID: PMC3912958 - DOI: 10.3324/haematol.2013.092452
Quantification of Mesenchymal Stem Cell (MSC) Delivery to a Target Site Using In Vivo Confocal Microscopy.
PLoS ONE. 2013;8(10):e78145 - PMID: 24205131 - PMCID: PMC3812161 - DOI: 10.1371/journal.pone.0078145
Tracking single cells in live animals using a photoconvertible near-infrared cell membrane label.
Soluble Guanylate Cyclase α1-Deficient Mice: A Novel Murine Model for Primary Open Angle Glaucoma.
Improved diffuse fluorescence flow cytometer prototype for high sensitivity detection of rare circulating cells in vivo.
J Biomed Opt. 2013;18(7):77002 - PMID: 23831714 - PMCID: PMC3702234 - DOI: 10.1117/1.JBO.18.7.077002
Soluble Guanylate Cyclase a1-Deficient Mice: a novel murine model for Primary Open Angle Glaucoma.
Myocardial infarction accelerates atherosclerosis
Hypoxia promotes dissemination of multiple myeloma through acquisition of endothelial to mesenchymal transition-like features.
Blood. 2012;119(24):5782-94 - PMID: 22394600 - PMCID: PMC3382938 - DOI: 10.1182/blood-2011-09-380410
Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration.
Cell Stem Cell. 2012;10(3):259-72 - PMID: 22385654 - PMCID: PMC3652251 - DOI: 10.1016/j.stem.2012.02.003
Molecular imaging of fibrin deposition in deep vein thrombosis using fibrin-targeted near-infrared fluorescence.
JACC Cardiovasc Imaging. 2012;5(6):607-15 - PMID: 22698530 - PMCID: PMC3376390 - DOI: 10.1016/j.jcmg.2012.01.017
Tracking Mesenchymal Stem Cells with Iron Oxide Nanoparticle Loaded Poly(lactide-co-glycolide) Microparticles.
Inflammation Modulates Murine Venous Thrombosis Resolution In Vivo: Assessment by Multimodal Fluorescence Molecular Imaging.
Arterioscler Thromb Vasc Biol. 2012;32(11):2616-24 - PMID: 22995524 - PMCID: PMC3516622 - DOI: 10.1161/ATVBAHA.112.251983
Multifunctional nanoagent for thrombus-targeted fibrinolytic therapy.
Nanomedicine (Lond). 2012;7(7):1017-28 - PMID: 22348271 - PMCID: PMC3360120 - DOI: 10.2217/nnm.11.179
Three-color femtosecond source for simultaneous excitation of three fluorescent proteins in two-photon fluorescence microscopy.
Biomed Opt Express. 2012;3(9):1972-7 - PMID: 23024893 - PMCID: PMC3447541 - DOI: 10.1364/BOE.3.001972
Instrument for fluorescence sensing of circulating cells with diffuse light in mice in vivo.
J Biomed Opt. 2012;17(3):037001 - PMID: 22502573 - PMCID: PMC3380949 - DOI: 10.1117/1.JBO.17.3.037001
Tomographic sensing and localization of fluorescently labeled circulating cells in mice in vivo.
Phys Med Biol. 2012;57(14):4627-41 - PMID: 22750660 - PMCID: PMC3555500 - DOI: 10.1088/0031-9155/57/14/4627
Advances in Single-cell Tracking of Mesenchymal Stem Cells (MSCs) During Musculoskeletal Regeneration.
Orthop J Harv Med Sch. 2012;14:22-28 - PMID: 24244929 - PMCID: PMC3824625
In vivo tracking of hematopoietic cells in the retina of chimeric mice with a scanning laser ophthalmoscope
Intravital. 2012;1:132-140
In vivo imaging of T(reg) cells providing immune privilege to the haematopoietic stem-cell niche.
Cell-surface sensors for real-time probing of cellular environments.
Nat Nanotechnol. 2011;6(8):524-31 - PMID: 21765401 - PMCID: PMC3163485 - DOI: 10.1038/nnano.2011.101
P-selectin glycoprotein ligand regulates the interaction of multiple myeloma cells with the bone marrow microenvironment.
Defining the role of TORC1 and TORC2 in multiple myeloma.
Blood. 2011;118(26):6860-70 - PMID: 22045983 - PMCID: PMC3245208 - DOI: 10.1182/blood-2011-03-342394
Engineered cell homing.
Blood. 2011;118(25):e184-91 - PMID: 22034631 - PMCID: PMC3242725 - DOI: 10.1182/blood-2010-10-311464
Differential niche and Wnt requirements during acute myeloid leukemia progression.
Blood. 2011;118(10):2849-56 - PMID: 21765021 - PMCID: PMC3172801 - DOI: 10.1182/blood-2011-03-345165
IKKb regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways.
Diabetes impairs hematopoietic stem cell mobilization by altering niche function.
Sci Transl Med. 2011;3(104):104ra101 - PMID: 21998408 - PMCID: PMC3754876 - DOI: 10.1126/scitranslmed.3002191
FTY720 Blocks Egress of T Cells in Part by Abrogation of Their Adhesion on the Lymph Node Sinus.
An optical platform for cell tracking in adult zebrafish.
Cell labeling approaches for fluorescence-based in vivo flow cytometry.
In vivo evaluation of demyelination and remyelination in a nerve crush injury model.
Biomed Opt Express. 2011;2(9):2698-2708 - PMID: 22091449 - PMCID: PMC3184878 - DOI: 10.1364/BOE.2.002698
Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice.
Optical techniques for tracking multiple myeloma engraftment, growth, and response to therapy
Validation of a device for fluorescence sensing of rare circulating cells with diffusive light in an optical flow phantom model.
Conf Proc IEEE Eng Med Biol Soc. 2011;2011:486-9 - PMID: 22254354 - PMCID: PMC3555486 - DOI: 10.1109/IEMBS.2011.6090071
In vivo tracking of 'color-coded' effector, natural and induced regulatory T cells in the allograft response.
Regenerative Medicine Special Feature: Engineered vascularized bone grafts.
Proc Natl Acad Sci U S A. 2010;107(8):3311-6 - PMID: 20133604 - PMCID: PMC2840421 - DOI: 10.1073/pnas.0905445107
In vivo imaging of transplanted hematopoietic stem and progenitor cells in mouse calvarium bone marrow.
Imaging leukocyte trafficking in vivo with two-photon-excited endogenous tryptophan fluorescence.
Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells.
Exp Hematol. 2010;38(4):333-9 - PMID: 20167247 - PMCID: PMC3965294 - DOI: 10.1016/j.exphem.2010.02.003
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche.
Haematopoietic stem cells depend on Galpha(s)-mediated signalling to engraft bone marrow.
CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy.
Rho-A and Rac-1 GTPases play major and differential roles in SDF1-induced cell adhesion and chemotaxis in multiple myeloma.
microRNAs 15a and 16 regulate tumor proliferation in multiple myeloma.
Blood. 2009;113(26):6669-80 - PMID: 19401561 - PMCID: PMC2710922 - DOI: 10.1182/blood-2009-01-198408
Real-time in vivo assessment of the nerve microenvironment with coherent anti-Stokes Raman scattering microscopy.
Plast Reconstr Surg. 2009;123:123S-30S - PMID: 19182671 - DOI: 10.1097/PRS.0b013e318191c5b8
In vivo imaging of hematopoietic stem cells and their microenvironment.
J Biophotonics. 2009;2(11):619-631 - PMID: 19847800 - DOI: 10.1002/jbio.200910072
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036
In vivo observations of cell trafficking in allotransplanted vascularized skin flaps and conventional skin grafts.
J Plast Reconstr Aesthet Surg. 2009;63(4):711-9 - PMID: 19324598 - PMCID: PMC2835845 - DOI: 10.1016/j.bjps.2009.01.036
Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone.
Nature Med. 2008;14(2):181-7 - PMID: 18193058 - DOI: 10.1038/nm1703
In vivo cell tracking with video rate multimodality laser scanning microscopy
IEEE J Sel Top Quant. 2008;14:10:18
In vivo confocal and multiphoton microendoscopy.
Mechanisms of regulation of CXCR4/SDF-1 (CXCL12)-dependent migration and homing in multiple myeloma.
The Akt pathway regulates survival and homing in Waldenstrom macroglobulinemia.
Optical imaging of the adoptive transfer of human endothelial cells in mice using anti-human CD31 monoclonal antibody.
Pharmacol Res. 2007;24:1186-92 - PMID: 17373582 - PMCID: PMC2795329 - DOI: 10.1007/s11095-006-9219-7
Selective targeting of the retinal pigment epithelium in rabbit eyes with a scanning laser beam.
Invest Ophth Vis Sci. 2007;48:1782-92 - PMID: 17389512 - DOI: 10.1167/iovs.06-0797
Retinal flow cytometer.
In vivo fluorescent imaging of the mouse retina using adaptive optics.
Portable two-color in vivo flow cytometer for real-time detection of fluorescently-labeled circulating cells.
Optical detection of intracellular cavitation during selective laser targeting of the retinal pigment epithelium: dependence of cell death mechanism on pulse duration.
J Biomed Opt. 2007;12:064034 - PMID: 18163850 - DOI: 10.1117/1.2804078
G-CSF induces E-selectin ligand expression on human myeloid cells.
Nature Med. 2006;12:1185-90 - PMID: 16980970 - DOI: 10.1038/nm1470
An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues.
In vivo imaging flow cytometer.
Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in 'endocytosis-resistant' membrane domains after vasopressin treatment.
Biol Cell. 2006;98(4):215-32 - PMID: 16563128 - DOI: 10.1042/BC20040054
Imaging molecular expression on vascular endothelial cells by in vivo immunofluorescence microscopy.
Mol Imaging. 2006;5:31-40 - PMID: 16779968 - PMCID: PMC2801601
Selective targeting of the retinal pigment epithelium using an acousto-optic laser scanner.
J Biomed Opt. 2006;10(6):064014 - PMID: 16409079 - DOI: 10.1117/1.2136314
In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment.
Chemical imaging of tissue in vivo with video-rate coherent anti-Stokes Raman scattering microscopy.
Proc Natl Acad Sci U S A. 2005;102:16807-12 - PMID: 16263923 - PMCID: PMC1283840 - DOI: 10.1073/pnas.0508282102
[Selective RPE laser treatment with a scanned cw laser beam in rabbits]
Ophthalmologie. 2005;102(5):491-6 - PMID: 15883846 - DOI: 10.1007/s00347-004-1139-5
Real-time detection of circulating apoptotic cells by in vivo flow cytometry.
VEGF-A overexpression leads to lymphatic vessel enlargement and persistent skin inflammation
Blood. 2004;104:1048-57
In vivo flow cytometry: a new method for enumerating circulating cancer cells.
Cancer Res. 2004;64(15):5044-7 - PMID: 15289300 - PMCID: PMC2824432 - DOI: 10.1158/0008-5472.CAN-04-1058
In vivo flow cytometer for real-time detection and quantification of circulating cells.
Pump-probe detection of laser-induced microbubble formation in retinal pigment epithelium cells.
J Biomed Opt. 2004;9:367-71 - PMID: 15065904 - DOI: 10.1117/1.1646413
Selective cell targeting with light-absorbing microparticles and nanoparticles.
Biophys J. 2003;84:4023-32 - PMID: 12770906 - PMCID: PMC1302982 - DOI: 10.1016/S0006-3495(03)75128-5
Selective uptake of indocyanine green by reticulocytes in circulation.
Invest Ophth Vis Sci. 2003;44:4489-96 - PMID: 14507897 - PMCID: PMC2830078 - DOI: 10.1167/iovs.03-0041
Targeting of the retinal pigment epithelium (RPE) by means of a rapidly scanned continuous wave (CW) laser beam.
Laser Surg Med. 2003;32:252-64 - PMID: 12696092 - DOI: 10.1002/lsm.10150
Optical temperature probe
Appl Phys Lett. 2001;78:2381-3
Laser-beam-triggered microcavitation: a novel method for selective cell destruction.
2001;156:399-407 - PMID: 11554851 - DOI: 10.1667/0033-7587(2001)156[0399:lbtman]2.0.co;2
Fiber-coupled multiplexed confocal microscope.
Opt Lett. 2000;25:954-6 - PMID: 18064238 - DOI: 10.1364/ol.25.000954
Origin of retinal pigment epithelium cell damage by pulsed laser irradiance in the nanosecond to microsecond time regimen.
Laser Surg Med. 2000;27(5):451-64 - PMID: 11126439 - DOI: 10.1002/1096-9101(2000)27:5<451::AID-LSM1006>3.0.CO;2-1
Reactive oxidizing species produced near the plasma membrane induce apoptosis in bovine aorta endothelial cells.
2000;259:351-9 - PMID: 10964502 - DOI: 10.1006/excr.2000.4979
Selective Cell Killing by Microparticle Absorption of Pulsed Laser Radiation
IEEE J Sel Top Quant. 1999;5:963-8
Precise, controlled laser delivery with evanescent optical waves.
Appl Optics. 1999;38(25):5511-7 - PMID: 18324060 - DOI: 10.1364/ao.38.005511
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