Breton, Sylvie, PhD
Sylvie Breton is a PhD in Biophysics who specializes in the cell biology of membrane transport. She studies luminal acidification and intercellular communication networks in the kidney and epididymis. She became Professor of Medicine at Harvard Medical School in 2012, and she has been at MGH since 1994.
Selected Publications (from total of 117)
Reply to Edemir: Physiological regulation and single-cell RNA sequencing.
Extracellular Adenosine Stimulates Vacuolar ATPase-Dependent Proton Secretion in Medullary Intercalated Cells.
Pattern of protein expression in the epididymis of Oligoryzomys nigripes (Cricetidae, Sigmodontinae).
Transcriptomes of major renal collecting duct cell types in mouse identified by single-cell RNA-seq.
Relative contribution of clear cells and principal cells to luminal pH in the mouse epididymis.
The expression patterns of aquaporin 9, vacuolar H(+)-ATPase, and cytokeratin 5 in the epididymis of the common vampire bat.
The a3 isoform of subunit a of the vacuolar ATPase localizes to the plasma membrane of invasive breast tumor cells and is overexpressed in human breast cancer.
Tyrosine kinase-mediated axial motility of basal cells revealed by intravital imaging.
The MAPK/ERK-Signaling Pathway Regulates the Expression and Distribution of Tight Junction Proteins in the Mouse Proximal Epididymis.
Regulation of epithelial function, differentiation, and remodeling in the epididymis.
Mapping the H(+) (V)-ATPase interactome: identification of proteins involved in trafficking, folding, assembly and phosphorylation.
Localization of the gap junction protein, connexin 43, and E-cadherin/Cadherin-1 in the proximal mouse epididymis.
Mol Reprod Dev. 2015;82(10):723 - PMID: 26331361
Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor.
Role of Testicular Luminal Factors on Basal Cell Elongation and Proliferation in the Mouse Epididymis.
CFTR interacts with ZO-1 to regulate tight junction assembly and epithelial differentiation via the ZONAB pathway.